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Gene: Egf (epidermal growth factor) Mus musculus
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Symbol: Egf
Name: epidermal growth factor
Description: Exhibits epidermal growth factor receptor binding activity. Involved in several processes, including negative regulation of cholesterol efflux; positive regulation of cellular protein metabolic process; and positive regulation of cerebellar granule cell precursor proliferation. Localizes to the extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Zollinger-Ellison syndrome; hepatobiliary system cancer (multiple); lung cancer (multiple); malignant glioma (multiple); and primary hypomagnesemia (multiple). Is expressed in several structures, including 1st branchial arch; alimentary system; brain; genitourinary system; and liver and biliary system. Orthologous to human EGF (epidermal growth factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI790464; pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF)
Orthologs:
Homo sapiens (human) : EGF (epidermal growth factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egf (epidermal growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egf (epidermal growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : EGF (epidermal growth factor)
Canis lupus familiaris (dog) : EGF (epidermal growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egf (epidermal growth factor)
Sus scrofa (pig) : EGF (epidermal growth factor)
more info ...
Related Pseudogenes: Gm18238  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm383129,677,574 - 129,755,322 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373129,380,493 - 129,458,240 (-)NCBIGRCm37mm9NCBIm37
MGSCv363129,669,600 - 129,747,338 (-)NCBImm8
Celera3136,187,440 - 136,268,006 (-)NCBICelera
Cytogenetic Map3 G3NCBI
cM Map358.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Egf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10510
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.