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Gene: Egf (epidermal growth factor) Mus musculus
Symbol: Egf
Name: epidermal growth factor
Description: Exhibits epidermal growth factor receptor binding activity. Involved in several processes, including negative regulation of cholesterol efflux; positive regulation of cellular protein metabolic process; and positive regulation of cerebellar granule cell precursor proliferation. Localizes to the extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Zollinger-Ellison syndrome; hepatobiliary system cancer (multiple); lung cancer (multiple); malignant glioma (multiple); and primary hypomagnesemia (multiple). Is expressed in several structures, including 1st branchial arch; alimentary system; brain; genitourinary system; and liver and biliary system. Orthologous to human EGF (epidermal growth factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI790464; pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF)
Homo sapiens (human) : EGF (epidermal growth factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egf (epidermal growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egf (epidermal growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : EGF (epidermal growth factor)
Canis lupus familiaris (dog) : EGF (epidermal growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egf (epidermal growth factor)
Sus scrofa (pig) : EGF (epidermal growth factor)
more info ...
Related Pseudogenes: Gm18238  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383129,677,574 - 129,755,322 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373129,380,493 - 129,458,240 (-)NCBIGRCm37mm9NCBIm37
MGSCv363129,669,600 - 129,747,338 (-)NCBImm8
Celera3136,187,440 - 136,268,006 (-)NCBICelera
Cytogenetic Map3 G3NCBI
cM Map358.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Egf
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10510
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.