Rho (rhodopsin) - Rat Genome Database

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Gene: Rho (rhodopsin) Mus musculus
Analyze
Symbol: Rho
Name: rhodopsin
RGD ID: 11239
MGI Page MGI
Description: Predicted to enable G protein-coupled photoreceptor activity; retinal binding activity; and spectrin binding activity. Involved in photoreceptor cell maintenance. Acts upstream of or within several processes, including adaptation of rhodopsin mediated signaling; podosome assembly; and rod bipolar cell differentiation. Located in several cellular components, including rod photoreceptor outer segment; sperm head plasma membrane; and sperm midpiece. Is expressed in several structures, including brain; eye; and heart. Used to study retinitis pigmentosa and retinitis pigmentosa 4. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 1; fundus albipunctatus; night blindness; retinitis pigmentosa; and retinitis pigmentosa 4. Orthologous to human RHO (rhodopsin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: L opsin; Long Wavelength Sensitive opsin; LWS opsin; MGC21585; MGC25387; Noe; Noerg1; O; Opn2; Ops; opsin 2; R; Red Opsin; Rod Opsin; RP4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   SD-Tg(Rho*P23H)1LavRrrc  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396115,903,741 - 115,916,999 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6115,908,709 - 115,916,997 (+)EnsemblGRCm39 Ensembl
GRCm386115,926,754 - 115,940,038 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6115,931,748 - 115,940,036 (+)EnsemblGRCm38mm10GRCm38
MGSCv376115,881,945 - 115,888,848 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366115,897,546 - 115,904,449 (+)NCBIMGSCv36mm8
Celera6117,767,245 - 117,774,151 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal a-wave shape  (IAGP)
abnormal cone electrophysiology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal ocular fundus morphology  (IAGP)
abnormal photoreceptor outer segment morphology  (IAGP)
abnormal retina cone cell morphology  (IAGP)
abnormal retina horizontal cell morphology  (IAGP)
abnormal retina inner nuclear layer morphology  (IAGP)
abnormal retina layer morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina neuronal layer morphology  (IAGP)
abnormal retina outer nuclear layer morphology  (IAGP)
abnormal retina photoreceptor layer morphology  (IAGP)
abnormal retina photoreceptor morphology  (IAGP)
abnormal retina pigment epithelium morphology  (IAGP)
abnormal retina pigmentation  (IAGP)
abnormal retina rod bipolar cell morphology  (IAGP)
abnormal retina rod cell morphology  (IAGP)
abnormal retina rod cell outer segment morphology  (IAGP)
abnormal retina vasculature morphology  (IAGP)
abnormal retinol level  (IAGP)
abnormal rod electrophysiology  (IAGP)
abnormal vision  (IAGP)
absent b-wave  (IAGP)
absent photoreceptor outer segment  (IAGP)
decreased a-wave amplitude  (IAGP)
decreased b-wave amplitude  (IAGP)
decreased retina photoreceptor cell number  (IAGP)
decreased retina rod cell number  (IAGP)
decreased total retina thickness  (IAGP)
delayed dark adaptation  (IAGP)
disorganized photoreceptor inner segment  (IAGP)
disorganized photoreceptor outer segment  (IAGP)
disorganized retina layers  (IAGP)
disorganized retina outer nuclear layer  (IAGP)
increased retina apoptosis  (IAGP)
microgliosis  (IAGP)
photosensitivity  (IAGP)
retina degeneration  (IAGP)
retina detachment  (IAGP)
retina outer nuclear layer degeneration  (IAGP)
retina photoreceptor degeneration  (IAGP)
retina rod cell degeneration  (IAGP)
short photoreceptor outer segment  (IAGP)
short retina rod cell outer segment  (IAGP)
thin retina inner nuclear layer  (IAGP)
thin retina outer nuclear layer  (IAGP)
thin retina outer plexiform layer  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A homozygous p.Glu150Lys mutation in the opsin gene of two Pakistani families with autosomal recessive retinitis pigmentosa. Azam M, etal., Mol Vis. 2009 Dec 3;15:2526-34.
2. Aberrant retinal tight junction and adherens junction protein expression in an animal model of autosomal dominant Retinitis pigmentosa: the Rho(-/-) mouse. Campbell M, etal., Exp Eye Res. 2006 Sep;83(3):484-92. Epub 2006 Apr 27.
3. Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration. Choudhury S, etal., Cell Death Dis. 2013 Mar 7;4:e528. doi: 10.1038/cddis.2013.34.
4. Genes and mutations causing retinitis pigmentosa. Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
5. Mutations within the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa. Dryja TP, etal., N Engl J Med. 1990 Nov 8;323(19):1302-7.
6. Heterozygous missense mutation in the rhodopsin gene as a cause of congenital stationary night blindness. Dryja TP, etal., Nat Genet. 1993 Jul;4(3):280-3.
7. Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme. Gorbatyuk M, etal., Exp Eye Res. 2007 Jan;84(1):44-52. Epub 2006 Nov 1.
8. Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) mice. Kennan A, etal., Hum Mol Genet. 2002 Mar 1;11(5):547-57.
9. Transport of truncated rhodopsin and its effects on rod function and degeneration. Lee ES and Flannery JG, Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2868-76.
10. AAV delivery of wild-type rhodopsin preserves retinal function in a mouse model of autosomal dominant retinitis pigmentosa. Mao H, etal., Hum Gene Ther. 2011 May;22(5):567-75. doi: 10.1089/hum.2010.140. Epub 2011 Mar 7.
11. Functional characterization of a novel c.614-622del rhodopsin mutation in a French pedigree with retinitis pigmentosa. Maubaret C, etal., Mol Vis. 2012;18:581-7. Epub 2012 Mar 2.
12. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
13. MGDs mouse GO annotations MGD data from the GO Consortium
14. MGD IEA MGD IEA
15. Rhodopsin C110Y mutation causes a type 2 autosomal dominant retinitis pigmentosa. Milla E, etal., Ophthalmic Genet. 1998 Sep;19(3):131-9.
16. Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa. Mussolino C, etal., EMBO Mol Med. 2011 Mar;3(3):118-28. doi: 10.1002/emmm.201000119. Epub 2011 Jan 26.
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. Identification of two mutations of the RHO gene in two Chinese families with retinitis pigmentosa: correlation between genotype and phenotype. Pan Z, etal., Mol Vis. 2012;18:3013-20. Epub 2012 Dec 14.
19. Enhanced cone dysfunction in rats homozygous for the P23H rhodopsin mutation. Pinilla I, etal., Neurosci Lett. 2005 Jul 1-8;382(1-2):16-21. Epub 2005 Mar 17.
20. Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse. Pinto LH, etal., Vis Neurosci. 2005 Sep-Oct;22(5):619-29.
21. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
22. Mouse MP Annotation Import Pipeline RGD automated import pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Rhodopsin p.N78I dominant mutation causing sectorial retinitis pigmentosa in a pedigree with intrafamilial clinical heterogeneity. Rivera-De la Parra D, etal., Gene. 2013 Apr 25;519(1):173-6. doi: 10.1016/j.gene.2013.01.048. Epub 2013 Feb 9.
26. Mice with a D190N mutation in the gene encoding rhodopsin: a model for human autosomal-dominant retinitis pigmentosa. Sancho-Pelluz J, etal., Mol Med. 2012 May 9;18:549-55. doi: 10.2119/molmed.2011.00475.
27. Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives. Sun H Biochim Biophys Acta. 2012 Jan;1821(1):99-112. Epub 2011 Jun 17.
28. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait. Wright AF, etal., Nat Rev Genet. 2010 Apr;11(4):273-84. doi: 10.1038/nrg2717.
Additional References at PubMed
PMID:1311971   PMID:1378069   PMID:1418997   PMID:1421760   PMID:1572642   PMID:1572667   PMID:1579993   PMID:1783381   PMID:1978723   PMID:2341153   PMID:2844600   PMID:2918924  
PMID:7523628   PMID:7594541   PMID:7822160   PMID:8093645   PMID:8180471   PMID:8313988   PMID:8378322   PMID:8380565   PMID:8398150   PMID:8516292   PMID:8530061   PMID:8575777  
PMID:8576239   PMID:8586432   PMID:8627415   PMID:8630490   PMID:8681798   PMID:8910484   PMID:9020854   PMID:9330629   PMID:9364238   PMID:9600923   PMID:9697703   PMID:9751768  
PMID:9843205   PMID:9892703   PMID:10097103   PMID:10235537   PMID:10349636   PMID:10367972   PMID:10369877   PMID:10399916   PMID:10725384   PMID:10824261   PMID:10903183   PMID:10973734  
PMID:11042159   PMID:11053306   PMID:11055434   PMID:11076861   PMID:11086991   PMID:11157890   PMID:11217851   PMID:11222515   PMID:11222546   PMID:11278688   PMID:11333267   PMID:11404411  
PMID:11466416   PMID:11468275   PMID:11477108   PMID:11493566   PMID:11497420   PMID:11528395   PMID:11714849   PMID:11747369   PMID:11773008   PMID:11803178   PMID:11910029   PMID:11960024  
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PMID:16602821   PMID:16617297   PMID:16639027   PMID:16651659   PMID:16687517   PMID:16702404   PMID:16723493   PMID:16868010   PMID:16873665   PMID:16959241   PMID:16979686   PMID:17044933  
PMID:17108167   PMID:17122148   PMID:17122149   PMID:17194706   PMID:17198696   PMID:17251443   PMID:17251447   PMID:17272282   PMID:17360618   PMID:17389515   PMID:17436273   PMID:17460245  
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PMID:18326732   PMID:18385078   PMID:18400900   PMID:18425122   PMID:18460603   PMID:18495199   PMID:18514541   PMID:18596157   PMID:18614536   PMID:18626943   PMID:18641643   PMID:18834879  
PMID:18926818   PMID:18974269   PMID:18987029   PMID:18987202   PMID:19014374   PMID:19053287   PMID:19060896   PMID:19088125   PMID:19092805   PMID:19136713   PMID:19147682   PMID:19268277  
PMID:19279690   PMID:19332056   PMID:19348429   PMID:19361994   PMID:19416500   PMID:19544586   PMID:19661229   PMID:19661232   PMID:19741247   PMID:19805139   PMID:19828801   PMID:20017954  
PMID:20081859   PMID:20107170   PMID:20110327   PMID:20155952   PMID:20203194   PMID:20207741   PMID:20237275   PMID:20333246   PMID:20404157   PMID:20463215   PMID:20532191   PMID:20574023  
PMID:20574024   PMID:20576849   PMID:20592197   PMID:20619750   PMID:20637750   PMID:20671280   PMID:20702833   PMID:20713727   PMID:20806040   PMID:20875817   PMID:20926680   PMID:20949055  
PMID:21038881   PMID:21051333   PMID:21052544   PMID:21087508   PMID:21138975   PMID:21148103   PMID:21151604   PMID:21177258   PMID:21212183   PMID:21224384   PMID:21228385   PMID:21267068  
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PMID:21813673   PMID:21857657   PMID:21873635   PMID:21873685   PMID:22031837   PMID:22051675   PMID:22068599   PMID:22090505   PMID:22110080   PMID:22169101   PMID:22171059   PMID:22183357  
PMID:22183407   PMID:22222602   PMID:22228100   PMID:22258620   PMID:22275801   PMID:22281059   PMID:22289036   PMID:22323600   PMID:22549882   PMID:22570183   PMID:22589437   PMID:22627278  
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PMID:23468924   PMID:23524971   PMID:23551889   PMID:23649630   PMID:23652001   PMID:23704327   PMID:23716657   PMID:23734084   PMID:23746204   PMID:23793062   PMID:23926259   PMID:23932931  
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PMID:38089586   PMID:38190419   PMID:38365903  


Genomics

Comparative Map Data
Rho
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396115,903,741 - 115,916,999 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6115,908,709 - 115,916,997 (+)EnsemblGRCm39 Ensembl
GRCm386115,926,754 - 115,940,038 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6115,931,748 - 115,940,036 (+)EnsemblGRCm38mm10GRCm38
MGSCv376115,881,945 - 115,888,848 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366115,897,546 - 115,904,449 (+)NCBIMGSCv36mm8
Celera6117,767,245 - 117,774,151 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.72NCBI
RHO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383129,528,639 - 129,535,344 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3129,528,639 - 129,535,344 (+)EnsemblGRCh38hg38GRCh38
GRCh373129,247,482 - 129,254,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,730,172 - 130,736,877 (+)NCBINCBI36Build 36hg18NCBI36
Build 343130,730,179 - 130,736,885NCBI
Celera3127,674,318 - 127,681,023 (+)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3126,630,783 - 126,637,404 (+)NCBIHuRef
CHM1_13129,210,611 - 129,217,316 (+)NCBICHM1_1
T2T-CHM13v2.03132,273,081 - 132,279,773 (+)NCBIT2T-CHM13v2.0
Rho
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84150,653,205 - 150,658,367 (+)NCBIGRCr8
mRatBN7.24148,975,597 - 148,988,693 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4148,980,611 - 148,985,773 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4155,209,107 - 155,214,199 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04150,993,130 - 150,998,222 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04149,616,029 - 149,621,121 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04147,832,136 - 147,837,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4147,832,136 - 147,837,298 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,115,847 - 211,121,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44152,057,788 - 152,062,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14152,302,628 - 152,307,791 (+)NCBI
Celera4137,870,273 - 137,875,435 (+)NCBICelera
Cytogenetic Map4q42NCBI
Rho
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,787,337 - 17,791,982 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,787,337 - 17,791,982 (-)NCBIChiLan1.0ChiLan1.0
RHO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22127,461,364 - 127,471,171 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13127,466,088 - 127,473,896 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03126,586,510 - 126,593,028 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13133,938,419 - 133,944,928 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3133,938,419 - 133,944,928 (+)Ensemblpanpan1.1panPan2
RHO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1205,630,735 - 5,638,906 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha205,669,643 - 5,674,903 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0205,661,948 - 5,667,219 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl205,661,632 - 5,667,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1205,377,793 - 5,383,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0205,730,818 - 5,736,090 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0205,706,443 - 5,711,705 (-)NCBIUU_Cfam_GSD_1.0
Rho
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494218,008,183 - 18,014,175 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936602894,617 - 901,664 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936602896,730 - 901,480 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1368,908,578 - 68,913,651 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11368,908,578 - 68,913,651 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21376,135,867 - 76,140,946 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RHO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12251,513,611 - 51,520,589 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2251,515,081 - 51,519,974 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041114,957,244 - 114,963,876 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rho
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624872523,912 - 527,615 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624872523,892 - 528,278 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rho
337 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:858
Count of miRNA genes:490
Interacting mature miRNAs:593
Transcripts:ENSMUST00000032471
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687480321121480516Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined688982366122982564Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
4141699Ibdq2_minflammatory bowel disease QTL 2 (mouse)Not determined105982366120894102Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112246918125333748Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
8552704Cia43_mcollagen induced arthritis QTL 43 (mouse)Not determined6114159241119737532Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse

Markers in Region
Rho  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv376115,883,275 - 115,883,434UniSTSGRCm37
Celera6117,768,575 - 117,768,738UniSTS
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
cM Map651.5UniSTS
BB282502  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386115,938,056 - 115,938,185UniSTSGRCm38
MGSCv376115,888,074 - 115,888,203UniSTSGRCm37
Celera6117,773,377 - 117,773,506UniSTS
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
Whitehead/MRC_RH61196.9UniSTS
D6Mit44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386115,933,269 - 115,933,416UniSTSGRCm38
MGSCv376115,883,287 - 115,883,434UniSTSGRCm37
Celera6117,768,587 - 117,768,738UniSTS
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
Whitehead Genetic648.1UniSTS
Whitehead_YAC6 UniSTS
M55171  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386115,938,288 - 115,938,436UniSTSGRCm38
MGSCv376115,888,306 - 115,888,454UniSTSGRCm37
Celera6117,773,609 - 117,773,757UniSTS
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
Whitehead/MRC_RH61196.9UniSTS
PMC17675P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386115,935,110 - 115,935,627UniSTSGRCm38
MGSCv376115,885,128 - 115,885,645UniSTSGRCm37
Celera6117,770,432 - 117,770,949UniSTS
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
Rho  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386115,933,257 - 115,933,416UniSTSGRCm38
MGSCv376115,883,275 - 115,883,434UniSTSGRCm37
Celera6117,768,575 - 117,768,738UniSTS
Cytogenetic Map6E3UniSTS
Rho  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6E3UniSTS
cM Map651.5UniSTS
Rho  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6E3UniSTS


Related Rat Strains
The following Strains have been annotated to Rho


Expression


Sequence


RefSeq Acc Id: ENSMUST00000032471   ⟹   ENSMUSP00000032471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,908,709 - 115,916,997 (+)Ensembl
GRCm38.p6 Ensembl6115,931,748 - 115,940,036 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203284
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,911,699 - 115,913,005 (+)Ensembl
GRCm38.p6 Ensembl6115,934,738 - 115,936,044 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,912,158 - 115,913,189 (+)Ensembl
GRCm38.p6 Ensembl6115,935,197 - 115,936,228 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203531
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,908,886 - 115,911,059 (+)Ensembl
GRCm38.p6 Ensembl6115,931,925 - 115,934,098 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203877   ⟹   ENSMUSP00000144952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,911,302 - 115,913,913 (+)Ensembl
GRCm38.p6 Ensembl6115,934,341 - 115,936,952 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204493   ⟹   ENSMUSP00000145464
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,911,333 - 115,914,033 (+)Ensembl
GRCm38.p6 Ensembl6115,934,372 - 115,937,072 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204711   ⟹   ENSMUSP00000144768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6115,909,517 - 115,913,668 (+)Ensembl
GRCm38.p6 Ensembl6115,932,556 - 115,936,707 (+)Ensembl
RefSeq Acc Id: NM_145383   ⟹   NP_663358
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396115,908,869 - 115,916,999 (+)NCBI
GRCm386115,931,908 - 115,940,038 (+)NCBI
MGSCv376115,881,945 - 115,888,848 (+)RGD
Celera6117,767,245 - 117,774,151 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505860   ⟹   XP_006505923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396115,908,365 - 115,916,997 (+)NCBI
GRCm386115,931,404 - 115,940,036 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505861   ⟹   XP_006505924
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396115,903,741 - 115,916,997 (+)NCBI
GRCm386115,926,754 - 115,940,036 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321493   ⟹   XP_017176982
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396115,905,668 - 115,916,997 (+)NCBI
GRCm386115,928,707 - 115,940,036 (+)NCBI
Sequence:
RefSeq Acc Id: NP_663358   ⟸   NM_145383
- UniProtKB: Q8K0D8 (UniProtKB/Swiss-Prot),   Q96DZ2 (UniProtKB/Swiss-Prot),   P15409 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505924   ⟸   XM_006505861
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006505923   ⟸   XM_006505860
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017176982   ⟸   XM_017321493
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSMUSP00000144952   ⟸   ENSMUST00000203877
RefSeq Acc Id: ENSMUSP00000032471   ⟸   ENSMUST00000032471
RefSeq Acc Id: ENSMUSP00000145464   ⟸   ENSMUST00000204493
RefSeq Acc Id: ENSMUSP00000144768   ⟸   ENSMUST00000204711
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15409-F1-model_v2 AlphaFold P15409 1-348 view protein structure

Promoters
RGD ID:6890742
Promoter ID:EPDNEW_M8822
Type:multiple initiation site
Name:Rho_1
Description:Mus musculus rhodopsin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386115,931,908 - 115,931,968EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97914 AgrOrtholog
Ensembl Genes ENSMUSG00000030324 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032471 ENTREZGENE
  ENSMUST00000032471.9 UniProtKB/Swiss-Prot
  ENSMUST00000203877.2 UniProtKB/TrEMBL
  ENSMUST00000204493.2 UniProtKB/TrEMBL
  ENSMUST00000204711.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Opsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Retinal_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin_N UniProtKB/Swiss-Prot
KEGG Report mmu:212541 UniProtKB/Swiss-Prot
MGD MGI:97914 ENTREZGENE
NCBI Gene 212541 ENTREZGENE
PANTHER OPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHODOPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin_N UniProtKB/Swiss-Prot
PhenoGen Rho PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHODOPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUP8_MOUSE UniProtKB/TrEMBL
  A0A0N4SV48_MOUSE UniProtKB/TrEMBL
  A0A0N4SWC6_MOUSE UniProtKB/TrEMBL
  OPSD_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TPK4_MOUSE UniProtKB/TrEMBL
  Q8K0D8 ENTREZGENE
  Q96DZ2 ENTREZGENE
UniProt Secondary Q8K0D8 UniProtKB/Swiss-Prot
  Q96DZ2 UniProtKB/Swiss-Prot