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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ccdc136 | Mouse | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CCDC136 mRNA | CTD | PMID:21955143 | Ccdc136 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CCDC136 mRNA | CTD | PMID:22206623 | Ccdc136 | Mouse | 2-methylcholine | affects expression | ISO | CCDC136 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of CCDC136 mRNA | CTD | PMID:21179406 | Ccdc136 | Mouse | 2-palmitoylglycerol | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of CCDC136 mRNA | CTD | PMID:37199045 | Ccdc136 | Mouse | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | 3 more ... | CTD | PMID:32119087 | Ccdc136 | Mouse | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CCDC136 mRNA | CTD | PMID:26251327 | Ccdc136 | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCDC136 mRNA | CTD | PMID:28628672 | Ccdc136 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCDC136 mRNA | CTD | PMID:28628672 | Ccdc136 | Mouse | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of CCDC136 mRNA | CTD | PMID:28973697 | Ccdc136 | Mouse | 5-aza-2'-deoxycytidine | affects expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Decitabine affects the expression of CCDC136 mRNA | CTD | PMID:23300844 | Ccdc136 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of CCDC136 mRNA | CTD | PMID:30047161 | Ccdc136 | Mouse | acrylamide | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of CCDC136 mRNA | CTD | PMID:32763439 | Ccdc136 | Mouse | aflatoxin B1 | decreases methylation | ISO | CCDC136 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CCDC136 intron | CTD | PMID:30157460 | Ccdc136 | Mouse | all-trans-retinoic acid | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CCDC136 mRNA | CTD | PMID:21934132 and PMID:33167477 | Ccdc136 | Mouse | alpha-Zearalanol | multiple interactions | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of CCDC136 mRNA | CTD | PMID:35163327 | Ccdc136 | Mouse | amitrole | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of CCDC136 mRNA | CTD | PMID:30047161 | Ccdc136 | Mouse | antirheumatic drug | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CCDC136 mRNA | CTD | PMID:24449571 | Ccdc136 | Mouse | benzo[a]pyrene | decreases methylation | ISO | CCDC136 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CCDC136 promoter | CTD | PMID:27901495 | Ccdc136 | Mouse | benzo[a]pyrene | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of CCDC136 mRNA | CTD | PMID:32234424 | Ccdc136 | Mouse | benzo[a]pyrene | affects methylation | ISO | CCDC136 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CCDC136 exon | CTD | PMID:27901495 | Ccdc136 | Mouse | beta-lapachone | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of CCDC136 mRNA | CTD | PMID:38218311 | Ccdc136 | Mouse | bis(2-ethylhexyl) phthalate | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of CCDC136 mRNA | CTD | PMID:31163220 | Ccdc136 | Mouse | bisphenol A | increases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of CCDC136 mRNA | CTD | PMID:25181051 | Ccdc136 | Mouse | Brodifacoum | increases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of CCDC136 protein | CTD | PMID:28903499 | Ccdc136 | Mouse | C60 fullerene | increases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | fullerene C60 results in increased expression of CCDC136 mRNA | CTD | PMID:19167457 | Ccdc136 | Mouse | CGP 52608 | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CCDC136 gene] | CTD | PMID:28238834 | Ccdc136 | Mouse | chlordecone | decreases expression | EXP | | 6480464 | Chlordecone results in decreased expression of CCDC136 mRNA | CTD | PMID:33711761 | Ccdc136 | Mouse | cisplatin | affects expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Cisplatin affects the expression of CCDC136 mRNA | CTD | PMID:23300844 | Ccdc136 | Mouse | Cuprizon | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of CCDC136 mRNA | CTD | PMID:26577399 | Ccdc136 | Mouse | dexamethasone | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCDC136 mRNA | CTD | PMID:28628672 | Ccdc136 | Mouse | Dibutyl phosphate | affects expression | ISO | CCDC136 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of CCDC136 mRNA | CTD | PMID:37042841 | Ccdc136 | Mouse | dichloroacetic acid | decreases expression | EXP | | 6480464 | Dichloroacetic Acid results in decreased expression of CCDC136 mRNA | CTD | PMID:28962523 | Ccdc136 | Mouse | dorsomorphin | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc136 | Mouse | entinostat | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | entinostat | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | entinostat results in decreased expression of CCDC136 mRNA | CTD | PMID:26272509 | Ccdc136 | Mouse | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of CCDC136 mRNA | CTD | PMID:21955143 | Ccdc136 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of CCDC136 mRNA | CTD | PMID:30319688 | Ccdc136 | Mouse | ethyl methanesulfonate | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of CCDC136 mRNA | CTD | PMID:23649840 | Ccdc136 | Mouse | fipronil | increases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of CCDC136 mRNA | CTD | PMID:34044035 | Ccdc136 | Mouse | formaldehyde | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CCDC136 mRNA | CTD | PMID:23649840 | Ccdc136 | Mouse | indometacin | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCDC136 mRNA | CTD | PMID:28628672 | Ccdc136 | Mouse | menadione | decreases expression | EXP | | 6480464 | Vitamin K 3 results in decreased expression of CCDC136 mRNA | CTD | PMID:25270620 | Ccdc136 | Mouse | mercury dibromide | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of CCDC136 mRNA | CTD | PMID:26272509 | Ccdc136 | Mouse | mercury dibromide | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | methimazole | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of CCDC136 mRNA | CTD | PMID:30047161 | Ccdc136 | Mouse | methyl methanesulfonate | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of CCDC136 mRNA | CTD | PMID:23649840 | Ccdc136 | Mouse | methylmercury chloride | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CCDC136 mRNA | CTD | PMID:28001369 | Ccdc136 | Mouse | morphine | decreases expression | EXP | | 6480464 | Morphine results in decreased expression of CCDC136 mRNA | CTD | PMID:21955143 | Ccdc136 | Mouse | N-nitrosodiethylamine | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Diethylnitrosamine results in increased expression of CCDC136 mRNA | CTD | PMID:21527772 | Ccdc136 | Mouse | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CCDC136 mRNA | CTD | PMID:21955143 | Ccdc136 | Mouse | p-chloromercuribenzoic acid | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of CCDC136 mRNA | CTD | PMID:26272509 | Ccdc136 | Mouse | p-chloromercuribenzoic acid | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | panobinostat | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of CCDC136 mRNA | CTD | PMID:26272509 | Ccdc136 | Mouse | panobinostat | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | paracetamol | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CCDC136 mRNA | CTD | PMID:29067470 | Ccdc136 | Mouse | paraquat | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of CCDC136 mRNA | CTD | PMID:32680482 | Ccdc136 | Mouse | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of CCDC136 mRNA | CTD | PMID:37995155 | Ccdc136 | Mouse | perfluorooctanoic acid | multiple interactions | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of CCDC136 mRNA | CTD | PMID:35163327 | Ccdc136 | Mouse | phenylmercury acetate | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of CCDC136 mRNA | CTD | PMID:26272509 | Ccdc136 | Mouse | phenylmercury acetate | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | SB 431542 | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc136 | Mouse | silicon dioxide | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of CCDC136 mRNA | CTD | PMID:25895662 | Ccdc136 | Mouse | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of CCDC136 protein | CTD | PMID:28918527 | Ccdc136 | Mouse | sulfadimethoxine | decreases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of CCDC136 mRNA | CTD | PMID:30047161 | Ccdc136 | Mouse | sunitinib | increases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CCDC136 mRNA | CTD | PMID:31533062 | Ccdc136 | Mouse | temozolomide | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of CCDC136 mRNA | CTD | PMID:31758290 | Ccdc136 | Mouse | thioacetamide | increases expression | ISO | Ccdc136 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of CCDC136 mRNA | CTD | PMID:23411599 | Ccdc136 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of CCDC136 gene | CTD | PMID:35295148 | Ccdc136 | Mouse | trichostatin A | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CCDC136 mRNA | CTD | PMID:24935251 and PMID:26272509 | Ccdc136 | Mouse | trichostatin A | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | triphenyl phosphate | affects expression | ISO | CCDC136 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CCDC136 mRNA | CTD | PMID:37042841 | Ccdc136 | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of CCDC136 mRNA | CTD | PMID:33045310 | Ccdc136 | Mouse | valproic acid | increases methylation | ISO | CCDC136 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CCDC136 gene | CTD | PMID:29154799 | Ccdc136 | Mouse | valproic acid | decreases expression | ISO | CCDC136 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CCDC136 mRNA | CTD | PMID:23179753 more ... | Ccdc136 | Mouse | valproic acid | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | Ccdc136 | Mouse | vorinostat | multiple interactions | ISO | CCDC136 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC136 mRNA | CTD | PMID:27188386 | |