(+)-catechin decreases activity ISO RGD:1354178 6480464 Catechin results in decreased activity of DNMT1 protein CTD PMID:16037419 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1354178 6480464 epigallocatechin gallate binds to and results in decreased activity of DNMT1 protein, Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein] CTD PMID:14633667 , PMID:16037419 (-)-epigallocatechin 3-gallate increases expression ISO RGD:1354178 6480464 epigallocatechin gallate results in increased expression of DNMT1 mRNA CTD PMID:25839702 (-)-epigallocatechin 3-gallate decreases activity ISO RGD:1354178 6480464 epigallocatechin gallate results in decreased activity of DNMT1 protein CTD PMID:16037419 (S)-nicotine decreases expression ISO RGD:620979 6480464 Nicotine results in decreased expression of DNMT1 mRNA CTD PMID:28555334 (S)-nicotine multiple interactions ISO RGD:620979 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 1,2-dimethylhydrazine multiple interactions ISO RGD:620979 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in decreased expression of DNMT1 mRNA CTD PMID:27840820 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of DNMT1 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine increases expression EXP 6480464 1, 2-Dimethylhydrazine results in increased expression of DNMT1 mRNA CTD PMID:22206623 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile affects expression ISO RGD:620979 6480464 Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 1-chloro-2,4-dinitrobenzene affects binding ISO RGD:1354178 6480464 Dinitrochlorobenzene binds to DNMT1 protein CTD PMID:32991956 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of DNMT1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1354178 6480464 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]] more ... CTD PMID:20631324 more ... 17beta-estradiol increases expression ISO RGD:1354178 6480464 Estradiol results in increased expression of DNMT1 mRNA CTD PMID:30684530 , PMID:32030086 17beta-estradiol decreases phosphorylation ISO RGD:1354178 6480464 Estradiol results in decreased phosphorylation of DNMT1 protein CTD PMID:27026707 17beta-estradiol decreases expression ISO RGD:1354178 6480464 Estradiol results in decreased expression of DNMT1 mRNA CTD PMID:22952798 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:1354178 6480464 2 more ... CTD PMID:31675489 2,3',4,4',5-Pentachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:620979 6480464 Tetrachlorodibenzodioxin results in increased expression of DNMT1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:620979 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT1 mRNA CTD PMID:26455773 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1354178 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] promotes the reaction [DNMT1 protein binds to BRCA1 promoter] more ... CTD PMID:20631324 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:620979 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter]], Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter] CTD PMID:24136580 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of DNMT1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of DNMT1 mRNA CTD PMID:15667827 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT1 mRNA CTD PMID:16611356 2,6-dinitrotoluene affects expression ISO RGD:620979 6480464 2, 6-dinitrotoluene affects the expression of DNMT1 mRNA CTD PMID:21346803 3,3'-diindolylmethane decreases expression ISO RGD:1354178 6480464 3, 3'-diindolylmethane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression EXP 6480464 Dicarbethoxydihydrocollidine results in increased expression of DNMT1 mRNA CTD PMID:18098314 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 3-methylcholanthrene multiple interactions ISO RGD:620979 6480464 [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT1 mRNA CTD PMID:29741722 4,4'-sulfonyldiphenol increases expression ISO RGD:1354178 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT1 mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT1 protein CTD PMID:31601247 , PMID:32105160 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1354178 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [ESR1 protein binds to DNMT1 promoter] more ... CTD PMID:32105160 4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside decreases activity ISO RGD:1354178 6480464 lac dye results in decreased activity of DNMT1 protein CTD PMID:23839987 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of DNMT1 mRNA CTD PMID:28973697 5-(hydroxymethyl)cytosine multiple interactions ISO RGD:1354178 6480464 DNMT1 protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine], DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1354178 6480464 Decitabine affects the reaction [PARP1 protein affects the expression of DNMT1 mRNA] more ... CTD PMID:17621267 more ... 5-aza-2'-deoxycytidine multiple interactions ISO RGD:620979 6480464 Decitabine inhibits the reaction [Dust results in increased expression of DNMT1 mRNA] more ... CTD PMID:24211420 , PMID:30815999 5-aza-2'-deoxycytidine decreases expression EXP 6480464 Decitabine results in decreased expression of DNMT1 protein CTD PMID:19222872 , PMID:19679824 5-aza-2'-deoxycytidine affects response to substance ISO RGD:1354178 6480464 DNMT1 protein affects the susceptibility to Decitabine CTD PMID:17991895 5-aza-2'-deoxycytidine increases expression ISO RGD:1354178 6480464 Decitabine results in increased expression of DNMT1 mRNA CTD PMID:19117987 5-aza-2'-deoxycytidine decreases expression ISO RGD:1354178 6480464 Decitabine results in decreased expression of DNMT1 mRNA, Decitabine results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... 5-aza-2'-deoxycytidine increases degradation ISO RGD:1354178 6480464 Decitabine results in increased degradation of DNMT1 protein CTD PMID:19417133 5-aza-2'-deoxycytidine decreases activity ISO RGD:620979 6480464 Decitabine results in decreased activity of DNMT1 protein CTD PMID:21449042 5-aza-2'-deoxycytidine affects response to substance EXP 6480464 DNMT1 affects the susceptibility to Decitabine CTD PMID:14581508 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [Particulate Matter promotes the reaction [[ovalbumin-alum co-treated with Ovalbumin] results in increased expression of DNMT1 protein]], Decitabine inhibits the reaction [Particulate Matter results in increased expression of DNMT1 protein] CTD PMID:30481581 5-aza-2'-deoxycytidine decreases expression ISO RGD:620979 6480464 Decitabine results in decreased expression of DNMT1 protein CTD PMID:23423710 5-azacytidine multiple interactions ISO RGD:1354178 6480464 [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein, Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein] CTD PMID:19139132 , PMID:28901456 5-azacytidine decreases expression ISO RGD:1354178 6480464 Azacitidine results in decreased expression of DNMT1 protein CTD PMID:28901456 5-azacytidine decreases expression ISO RGD:620979 6480464 Azacitidine results in decreased expression of DNMT1 protein CTD PMID:19723570 , PMID:21224363 5-azacytidine multiple interactions ISO RGD:620979 6480464 [Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein, [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein CTD PMID:19723570 , PMID:21224363 6-prenylnaringenin multiple interactions ISO RGD:1354178 6480464 6-prenylnaringenin inhibits the reaction [DNMT1 protein binds to CYP1A1 promoter], 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]] CTD PMID:32986415 7,12-dimethyltetraphene increases expression ISO RGD:620979 6480464 9 more ... CTD PMID:12097258 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:24792773 7,12-dimethyltetraphene multiple interactions EXP 6480464 Butyric Acid affects the reaction [9 more ... CTD PMID:24792773 8-hydroxy-2'-deoxyguanosine affects abundance ISO RGD:1354178 6480464 DNMT1 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 8-hydroxy-2'-deoxyguanosine decreases activity ISO RGD:1354178 6480464 8-Hydroxy-2'-Deoxyguanosine results in decreased activity of DNMT1 protein CTD PMID:33052562 9-cis-retinoic acid multiple interactions ISO RGD:1354178 6480464 [Arsenicals co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA, [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA CTD PMID:34303791 acetamide increases expression ISO RGD:620979 6480464 acetamide results in increased expression of DNMT1 mRNA CTD PMID:31881176 acetic acid decreases expression ISO RGD:1354178 6480464 Acetic Acid results in decreased expression of DNMT1 protein CTD PMID:17065238 acrolein increases expression ISO RGD:620979 6480464 Acrolein results in increased expression of DNMT1 mRNA CTD PMID:35150775 acrylamide decreases expression ISO RGD:1354178 6480464 Acrylamide results in decreased expression of DNMT1 mRNA CTD PMID:32763439 aflatoxin B1 increases expression ISO RGD:620979 6480464 Aflatoxin B1 results in increased expression of DNMT1 mRNA CTD PMID:33354967 aldehydo-D-glucose increases expression ISO RGD:1354178 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 all-trans-retinoic acid decreases expression ISO RGD:1354178 6480464 Tretinoin results in decreased expression of DNMT1 mRNA CTD PMID:17273765 , PMID:33167477 allethrin multiple interactions ISO RGD:620979 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 amitriptyline decreases activity ISO RGD:620979 6480464 Amitriptyline results in decreased activity of DNMT1 protein CTD PMID:19924110 amphetamine decreases expression ISO RGD:620979 6480464 Amphetamine results in decreased expression of DNMT1 mRNA CTD PMID:30779732 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of DNMT1 protein] CTD PMID:22355787 arsane increases expression ISO RGD:620979 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:9380733 arsane affects response to substance ISO RGD:1354178 6480464 DNMT1 gene SNP affects the susceptibility to Arsenic CTD PMID:27292127 arsane increases expression ISO RGD:1354178 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:27838757 arsane affects methylation ISO RGD:1354178 6480464 Arsenic affects the methylation of DNMT1 gene CTD PMID:25304211 arsane decreases expression ISO RGD:620979 6480464 Arsenic results in decreased expression of DNMT1 protein CTD PMID:9380733 arsenic atom decreases expression ISO RGD:620979 6480464 Arsenic results in decreased expression of DNMT1 protein CTD PMID:9380733 arsenic atom increases expression ISO RGD:1354178 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:27838757 arsenic atom affects response to substance ISO RGD:1354178 6480464 DNMT1 gene SNP affects the susceptibility to Arsenic CTD PMID:27292127 arsenic atom affects methylation ISO RGD:1354178 6480464 Arsenic affects the methylation of DNMT1 gene CTD PMID:25304211 arsenic atom increases expression ISO RGD:620979 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:9380733 arsenous acid decreases expression ISO RGD:1354178 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA, Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA, [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA, Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:19679824 , PMID:23159075 arsenous acid decreases expression ISO RGD:620979 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA CTD PMID:29223816 arsenous acid multiple interactions ISO RGD:1354178 6480464 Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter] more ... CTD PMID:22558281 , PMID:28901456 arsenous acid increases expression ISO RGD:1354178 6480464 Arsenic Trioxide results in increased expression of DNMT1 mRNA CTD PMID:25534098 arsenous acid decreases activity ISO RGD:1354178 6480464 Arsenic Trioxide results in decreased activity of DNMT1 protein CTD PMID:20596618 atrazine decreases expression ISO RGD:1354178 6480464 Atrazine results in decreased expression of DNMT1 mRNA CTD PMID:22378314 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene inhibits the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter] CTD PMID:17682057 benzo[a]pyrene increases expression ISO RGD:1354178 6480464 Benzo(a)pyrene results in increased expression of DNMT1 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation ISO RGD:1354178 6480464 Benzo(a)pyrene results in increased methylation of DNMT1 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:1354178 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein] CTD PMID:21150308 benzo[a]pyrene increases degradation ISO RGD:1354178 6480464 Benzo(a)pyrene results in increased degradation of DNMT1 protein CTD PMID:21150308 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of DNMT1 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of DNMT1 mRNA CTD PMID:19770486 benzophenanthridine decreases expression ISO RGD:1354178 6480464 Benzophenanthridines analog results in decreased expression of DNMT1 mRNA CTD PMID:23117580 berberine decreases expression ISO RGD:1354178 6480464 Berberine results in decreased expression of DNMT1 mRNA CTD PMID:27311644 beta-naphthoflavone decreases expression ISO RGD:1354178 6480464 beta-Naphthoflavone results in decreased expression of DNMT1 mRNA CTD PMID:32858204 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of DNMT1 mRNA CTD PMID:26392148 bis(2-ethylhexyl) phthalate increases expression ISO RGD:620979 6480464 Diethylhexyl Phthalate results in increased expression of DNMT1 mRNA, Diethylhexyl Phthalate results in increased expression of DNMT1 protein CTD PMID:25280772 , PMID:30597186 bis(2-ethylhexyl) phthalate affects expression EXP 6480464 Diethylhexyl Phthalate affects the expression of DNMT1 mRNA CTD PMID:32628958 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of DNMT1 mRNA CTD PMID:25351189 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of DNMT1 mRNA CTD PMID:31211961 bisphenol A multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT1 mRNA], Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT1 mRNA] CTD PMID:22131059 , PMID:30892605 bisphenol A decreases methylation ISO RGD:1354178 6480464 bisphenol A results in decreased methylation of DNMT1 gene CTD PMID:31601247 bisphenol A multiple interactions ISO RGD:1354178 6480464 [bisphenol A co-treated with decabromobiphenyl ether] results in decreased expression of DNMT1 mRNA more ... CTD PMID:28597690 more ... bisphenol A decreases expression ISO RGD:1354178 6480464 bisphenol A results in decreased expression of DNMT1 mRNA, bisphenol A results in decreased expression of DNMT1 protein CTD PMID:28597690 more ... bisphenol A increases methylation ISO RGD:620979 6480464 bisphenol A results in increased methylation of DNMT1 gene CTD PMID:28505145 bisphenol A increases expression ISO RGD:1354178 6480464 bisphenol A results in increased expression of DNMT1 mRNA, bisphenol A results in increased expression of DNMT1 protein CTD PMID:28765096 more ... bisphenol A decreases expression ISO RGD:620979 6480464 bisphenol A results in decreased expression of DNMT1 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol A increases expression ISO RGD:620979 6480464 bisphenol A results in increased expression of DNMT1 mRNA, bisphenol A results in increased expression of DNMT1 protein CTD PMID:23791455 , PMID:32450286 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of DNMT1 exon CTD PMID:23716699 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of DNMT1 mRNA CTD PMID:23716699 , PMID:31201698 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of DNMT1 mRNA, bisphenol A results in increased expression of DNMT1 protein CTD PMID:25385582 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of DNMT1 mRNA, bisphenol A results in decreased expression of DNMT1 protein CTD PMID:21980460 more ... bisphenol F increases expression ISO RGD:1354178 6480464 bisphenol F results in increased expression of DNMT1 mRNA CTD PMID:31601247 bleomycin A2 affects response to substance ISO RGD:1354178 6480464 DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 Brodifacoum affects binding ISO RGD:1354178 6480464 bromfenacoum binds to DNMT1 protein CTD PMID:31595789 buta-1,3-diene decreases expression EXP 6480464 1 more ... CTD PMID:21147608 more ... butyric acid multiple interactions EXP 6480464 Butyric Acid affects the reaction [9 more ... CTD PMID:24792773 cadmium atom decreases activity ISO RGD:620979 6480464 Cadmium results in decreased activity of DNMT1 protein CTD PMID:21449042 cadmium atom affects response to substance ISO RGD:1354178 6480464 DNMT1 gene SNP affects the susceptibility to Cadmium CTD PMID:22382075 cadmium dichloride multiple interactions ISO RGD:1354178 6480464 [Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in decreased expression of ERCC1 mRNA more ... CTD PMID:22112500 cadmium dichloride decreases expression ISO RGD:620979 6480464 Cadmium Chloride results in decreased expression of DNMT1 mRNA, Cadmium Chloride results in decreased expression of DNMT1 protein CTD PMID:33865896 cadmium dichloride increases expression ISO RGD:1354178 6480464 Cadmium Chloride results in increased expression of DNMT1 mRNA, Cadmium Chloride results in increased expression of DNMT1 protein CTD PMID:22112500 more ... caffeine increases expression ISO RGD:620979 6480464 Caffeine results in increased expression of DNMT1 mRNA CTD PMID:24717552 calciol decreases expression ISO RGD:1354178 6480464 Cholecalciferol results in decreased expression of DNMT1 mRNA CTD PMID:21801466 calciol multiple interactions ISO RGD:1354178 6480464 Cholecalciferol promotes the reaction [Cladribine results in decreased expression of DNMT1 mRNA], Cladribine promotes the reaction [Cholecalciferol results in decreased expression of DNMT1 mRNA] CTD PMID:21801466 calcitriol decreases expression ISO RGD:1354178 6480464 Calcitriol results in decreased expression of DNMT1 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1354178 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT1 mRNA CTD PMID:21592394 cantharidin decreases expression ISO RGD:1354178 6480464 Cantharidin results in decreased expression of DNMT1 mRNA CTD PMID:32726682 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of DNMT1 mRNA CTD PMID:25554681 casticin decreases expression ISO RGD:1354178 6480464 casticin results in decreased expression of DNMT1 mRNA CTD PMID:32268151 casticin multiple interactions ISO RGD:1354178 6480464 casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein] more ... CTD PMID:32268151 casticin decreases activity ISO RGD:1354178 6480464 casticin results in decreased activity of DNMT1 protein CTD PMID:32268151 choline affects activity EXP 6480464 Choline affects the activity of DNMT1 protein CTD PMID:16855792 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 , PMID:25690533 chromium atom multiple interactions EXP 6480464 Chromium promotes the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter] CTD PMID:17682057 cisplatin decreases response to substance ISO RGD:620979 6480464 DNMT1 protein results in decreased susceptibility to Cisplatin CTD PMID:18314485 cisplatin decreases expression ISO RGD:620979 6480464 Cisplatin results in decreased expression of DNMT1 protein CTD PMID:19723570 cisplatin multiple interactions ISO RGD:620979 6480464 [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein CTD PMID:19723570 cisplatin decreases response to substance ISO RGD:1354178 6480464 DNMT1 protein results in decreased susceptibility to Cisplatin CTD PMID:18314485 , PMID:21458988 citalopram affects expression ISO RGD:620979 6480464 Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 cladribine decreases expression ISO RGD:1354178 6480464 Cladribine results in decreased expression of DNMT1 mRNA CTD PMID:21801466 cladribine multiple interactions ISO RGD:1354178 6480464 Cholecalciferol promotes the reaction [Cladribine results in decreased expression of DNMT1 mRNA], Cladribine promotes the reaction [Cholecalciferol results in decreased expression of DNMT1 mRNA] CTD PMID:21801466 clofibrate decreases expression ISO RGD:620979 6480464 Clofibrate results in decreased expression of DNMT1 mRNA, Clofibrate results in decreased expression of DNMT1 protein CTD PMID:28495587 cobalt dichloride decreases expression ISO RGD:1354178 6480464 cobaltous chloride results in decreased expression of DNMT1 mRNA CTD PMID:19320972 copper atom multiple interactions ISO RGD:1354178 6480464 [NSC 689534 binds to Copper] which results in decreased expression of DNMT1 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1354178 6480464 [NSC 689534 binds to Copper] which results in decreased expression of DNMT1 mRNA CTD PMID:20971185 coumestrol multiple interactions ISO RGD:1354178 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol increases expression ISO RGD:1354178 6480464 Coumestrol results in increased expression of DNMT1 mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO RGD:1354178 6480464 Asbestos more ... CTD PMID:32006662 Cuprizon increases expression ISO RGD:620979 6480464 Cuprizone results in increased expression of DNMT1 mRNA CTD PMID:26577399 curcumin decreases expression ISO RGD:1354178 6480464 Curcumin results in decreased expression of DNMT1 mRNA, Curcumin results in decreased expression of DNMT1 protein CTD PMID:23593078 curcumin affects expression EXP 6480464 Curcumin analog affects the expression of DNMT1 protein CTD PMID:29228771 curcumin increases activity ISO RGD:1354178 6480464 Curcumin results in increased activity of DNMT1 protein CTD PMID:27132804 curcumin multiple interactions ISO RGD:1354178 6480464 Curcumin promotes the reaction [Quercetin results in increased activity of DNMT1 protein], Quercetin promotes the reaction [Curcumin results in increased activity of DNMT1 protein] CTD PMID:27132804 curcumin decreases expression EXP 6480464 Curcumin analog results in decreased expression of DNMT1 protein CTD PMID:26991801 cyclophosphamide multiple interactions ISO RGD:1354178 6480464 Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein] CTD PMID:22007908 cyclophosphamide increases expression ISO RGD:1354178 6480464 Cyclophosphamide results in increased expression of DNMT1 protein CTD PMID:22007908 cyclophosphamide decreases methylation ISO RGD:1354178 6480464 Cyclophosphamide results in decreased methylation of DNMT1 protein CTD PMID:22007908 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of DNMT1 mRNA CTD PMID:19770486 cyclosporin A decreases expression ISO RGD:1354178 6480464 Cyclosporine results in decreased expression of DNMT1 mRNA CTD PMID:25562108 cyhalothrin multiple interactions ISO RGD:620979 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 cypermethrin multiple interactions ISO RGD:620979 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 D-glucose increases expression ISO RGD:1354178 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 daidzein multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 daidzein 7-O-beta-D-glucoside multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 DDE decreases expression ISO RGD:620979 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of DNMT1 mRNA CTD PMID:30153481 DDT decreases expression ISO RGD:620979 6480464 DDT results in decreased expression of DNMT1 mRNA CTD PMID:19797855 DDT increases expression ISO RGD:620979 6480464 DDT results in increased expression of DNMT1 mRNA, DDT results in increased expression of DNMT1 protein CTD PMID:25410620 decabromodiphenyl ether multiple interactions ISO RGD:1354178 6480464 [bisphenol A co-treated with decabromobiphenyl ether] results in decreased expression of DNMT1 mRNA CTD PMID:28597690 decabromodiphenyl ether decreases expression ISO RGD:1354178 6480464 decabromobiphenyl ether results in decreased expression of DNMT1 mRNA CTD PMID:28597690 deoxynivalenol increases expression ISO RGD:620979 6480464 deoxynivalenol results in increased expression of DNMT1 mRNA, deoxynivalenol results in increased expression of DNMT1 protein CTD PMID:32738333 deoxynivalenol affects phosphorylation EXP 6480464 deoxynivalenol affects the phosphorylation of DNMT1 protein CTD PMID:23352502 , PMID:23811945 desferrioxamine B increases expression ISO RGD:1354178 6480464 Deferoxamine results in increased expression of DNMT1 mRNA CTD PMID:23483119 desferrioxamine B decreases expression ISO RGD:1354178 6480464 Deferoxamine results in decreased expression of DNMT1 mRNA CTD PMID:23483119 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 diarsenic trioxide multiple interactions ISO RGD:1354178 6480464 Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter] more ... CTD PMID:22558281 , PMID:28901456 diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA, [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 diarsenic trioxide decreases activity ISO RGD:1354178 6480464 Arsenic Trioxide results in decreased activity of DNMT1 protein CTD PMID:20596618 diarsenic trioxide decreases expression ISO RGD:620979 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA CTD PMID:29223816 diarsenic trioxide decreases expression ISO RGD:1354178 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA, Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA, Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:19679824 , PMID:23159075 diarsenic trioxide increases expression ISO RGD:1354178 6480464 Arsenic Trioxide results in increased expression of DNMT1 mRNA CTD PMID:25534098 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of DNMT1 mRNA CTD PMID:21266533 , PMID:31318015 dicrotophos increases expression ISO RGD:1354178 6480464 dicrotophos results in increased expression of DNMT1 mRNA CTD PMID:28302478 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of DNMT1 mRNA CTD PMID:16714842 Difenacoum affects binding ISO RGD:1354178 6480464 difenacoum binds to DNMT1 protein CTD PMID:31595789 dihydro-beta-erythroidine multiple interactions ISO RGD:620979 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 dimethyl sulfate decreases expression ISO RGD:1354178 6480464 dimethyl sulfate results in decreased expression of DNMT1 protein CTD PMID:11912126 dimethyl sulfoxide decreases expression ISO RGD:1354178 6480464 Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 dioxygen increases expression ISO RGD:1354178 6480464 Oxygen deficiency results in increased expression of DNMT1 protein CTD PMID:18314485 dioxygen decreases expression ISO RGD:1354178 6480464 Oxygen deficiency results in decreased expression of DNMT1 mRNA CTD PMID:26516004 disodium selenite decreases expression ISO RGD:1354178 6480464 Sodium Selenite results in decreased expression of DNMT1 mRNA, Sodium Selenite results in decreased expression of DNMT1 protein CTD PMID:18676679 doxorubicin affects response to substance ISO RGD:1354178 6480464 DNMT1 protein affects the susceptibility to Doxorubicin CTD PMID:17991895 doxorubicin decreases expression ISO RGD:620979 6480464 Doxorubicin results in decreased expression of DNMT1 mRNA CTD PMID:30557669 doxorubicin multiple interactions ISO RGD:1354178 6480464 [Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]] which results in increased expression of RELN mRNA more ... CTD PMID:17065238 more ... elemental selenium affects activity ISO RGD:620979 6480464 Selenium affects the activity of DNMT1 protein CTD PMID:16632891 endosulfan increases expression ISO RGD:1354178 6480464 Endosulfan results in increased expression of DNMT1 mRNA, Endosulfan results in increased expression of DNMT1 protein CTD PMID:29054638 Enterolactone multiple interactions ISO RGD:1354178 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DNMT1 mRNA CTD PMID:19167446 entinostat multiple interactions ISO RGD:620979 6480464 [Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein CTD PMID:21224363 enzyme inhibitor multiple interactions ISO RGD:1354178 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DNMT1 protein CTD PMID:23301498 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of DNMT1 mRNA, Ethanol results in decreased expression of DNMT1 protein CTD PMID:23395981 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of DNMT1 mRNA CTD PMID:30319688 ethanol increases degradation EXP 6480464 Ethanol results in increased degradation of DNMT1 protein CTD PMID:23395981 ethanol multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of DNMT1 mRNA, benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein] CTD PMID:23395981 , PMID:30517762 etoposide decreases response to substance ISO RGD:620979 6480464 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 etoposide decreases response to substance ISO RGD:1354178 6480464 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 fenvalerate multiple interactions ISO RGD:620979 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 fisetin multiple interactions ISO RGD:1354178 6480464 [fisetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 Flocoumafen affects binding ISO RGD:1354178 6480464 flocoumafen binds to DNMT1 protein CTD PMID:31595789 folic acid affects expression ISO RGD:1354178 6480464 Folic Acid affects the expression of DNMT1 mRNA CTD PMID:17311948 , PMID:26492244 folic acid multiple interactions ISO RGD:1354178 6480464 APP protein affects the reaction [Folic Acid affects the expression of DNMT1 mRNA] CTD PMID:26492244 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of DNMT1 mRNA, Folic Acid results in increased expression of DNMT1 protein CTD PMID:30920123 folic acid affects expression EXP 6480464 Folic Acid affects the expression of DNMT1 mRNA CTD PMID:29986310 folic acid increases expression ISO RGD:1354178 6480464 Folic Acid results in increased expression of DNMT1 mRNA CTD PMID:23219837 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 more ... folic acid affects activity EXP 6480464 Folic Acid affects the activity of DNMT1 protein CTD PMID:16855792 formaldehyde increases expression ISO RGD:1354178 6480464 Formaldehyde results in increased expression of DNMT1 mRNA, Formaldehyde results in increased expression of DNMT1 protein CTD PMID:21745553 fulvestrant multiple interactions ISO RGD:1354178 6480464 [Fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA more ... CTD PMID:19016759 more ... fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT1 mRNA], Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT1 mRNA] CTD PMID:22131059 , PMID:30892605 fulvestrant decreases expression ISO RGD:1354178 6480464 Fulvestrant results in decreased expression of DNMT1 mRNA CTD PMID:19016759 , PMID:31601247 fumonisin B1 decreases activity ISO RGD:1354178 6480464 fumonisin B1 results in decreased activity of DNMT1 protein CTD PMID:24280379 gemcitabine multiple interactions ISO RGD:1354178 6480464 [DNMT1 protein binds to SFN promoter] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine] more ... CTD PMID:25189999 genistein decreases expression ISO RGD:1354178 6480464 Genistein results in decreased expression of DNMT1 mRNA, Genistein results in decreased expression of DNMT1 protein CTD PMID:16705744 more ... genistein increases expression ISO RGD:1354178 6480464 Genistein results in increased expression of DNMT1 mRNA CTD PMID:30684530 genistein multiple interactions ISO RGD:1354178 6480464 sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA] CTD PMID:30684530 genistein multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 genistein 7-O-beta-D-glucoside multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 glucaric acid multiple interactions EXP 6480464 Glucaric Acid affects the reaction [9 more ... CTD PMID:24792773 glucose increases expression ISO RGD:1354178 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 glycine betaine multiple interactions EXP 6480464 Betaine inhibits the reaction [CPT1A protein mutant form results in decreased expression of DNMT1 mRNA] CTD PMID:22945834 glycine betaine increases expression EXP 6480464 Betaine results in increased expression of DNMT1 mRNA CTD PMID:22945834 glycitein multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 glycitin multiple interactions ISO RGD:620979 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 glyphosate increases expression ISO RGD:1354178 6480464 glyphosate results in increased expression of DNMT1 mRNA CTD PMID:33803994 guggulsterone decreases expression ISO RGD:1354178 6480464 pregna-4 more ... CTD PMID:23593078 hexadecanoic acid increases phosphorylation ISO RGD:1354178 6480464 Palmitic Acid results in increased phosphorylation of DNMT1 protein CTD PMID:28073184 hexane decreases methylation ISO RGD:620979 6480464 n-hexane results in decreased methylation of DNMT1 promoter CTD PMID:23740543 homocysteine decreases activity ISO RGD:1354178 6480464 Homocysteine results in decreased activity of DNMT1 protein CTD PMID:17698632 homocysteine multiple interactions ISO RGD:1354178 6480464 DNMT1 protein affects the reaction [Homocysteine results in decreased expression of CCNA1 mRNA] CTD PMID:17698632 hydrogen peroxide increases expression ISO RGD:1354178 6480464 Hydrogen Peroxide results in increased expression of DNMT1 mRNA, Hydrogen Peroxide results in increased expression of DNMT1 protein CTD PMID:18314485 , PMID:27655674 hydrogen peroxide multiple interactions ISO RGD:1354178 6480464 [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA, [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased methylation of DNMT1 promoter CTD PMID:29854080 hydrogen peroxide decreases response to substance ISO RGD:620979 6480464 DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18314485 hydrogen peroxide decreases response to substance ISO RGD:1354178 6480464 DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18314485 hydroquinone decreases expression ISO RGD:1354178 6480464 hydroquinone results in decreased expression of DNMT1 mRNA, hydroquinone results in decreased expression of DNMT1 protein CTD PMID:22245671 more ... hydroquinone affects expression ISO RGD:1354178 6480464 hydroquinone affects the expression of DNMT1 mRNA CTD PMID:31899212 hydroxyurea affects response to substance ISO RGD:1354178 6480464 DNMT1 protein affects the susceptibility to Hydroxyurea CTD PMID:17991895 hypochlorous acid decreases expression EXP 6480464 Hypochlorous Acid results in decreased expression of DNMT1 mRNA CTD PMID:19376150 ionomycin multiple interactions ISO RGD:1354178 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein more ... CTD PMID:23775084 ivermectin decreases expression ISO RGD:1354178 6480464 Ivermectin results in decreased expression of DNMT1 protein CTD PMID:32959892 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 , PMID:25690533 lead diacetate decreases expression ISO RGD:620979 6480464 lead acetate results in decreased expression of DNMT1 mRNA, lead acetate results in decreased expression of DNMT1 protein CTD PMID:21117136 more ... lead diacetate multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which affects the expression of DNMT1 protein CTD PMID:29481626 lead diacetate increases expression ISO RGD:620979 6480464 lead acetate results in increased expression of DNMT1 mRNA, lead acetate results in increased expression of DNMT1 protein CTD PMID:22160880 , PMID:23246732 lead(0) decreases expression ISO RGD:1354178 6480464 Lead results in decreased expression of DNMT1 mRNA, Lead results in decreased expression of DNMT1 protein CTD PMID:22272629 lead(0) multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which affects the expression of DNMT1 protein CTD PMID:29481626 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of DNMT1 mRNA, Lead results in decreased expression of DNMT1 protein CTD PMID:27239543 lead(2+) decreases expression ISO RGD:1354178 6480464 Lead results in decreased expression of DNMT1 mRNA, Lead results in decreased expression of DNMT1 protein CTD PMID:22272629 lead(2+) multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which affects the expression of DNMT1 protein CTD PMID:29481626 lead(2+) decreases expression EXP 6480464 Lead results in decreased expression of DNMT1 mRNA, Lead results in decreased expression of DNMT1 protein CTD PMID:27239543 leptomycin B multiple interactions ISO RGD:1354178 6480464 [leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of DNMT1 mRNA CTD PMID:20803015 leptomycin B decreases expression ISO RGD:1354178 6480464 leptomycin B results in decreased expression of DNMT1 mRNA CTD PMID:20803015 linsidomine increases oxidation ISO RGD:620979 6480464 linsidomine results in increased oxidation of DNMT1 protein CTD PMID:28086193 magnesium atom decreases activity ISO RGD:1354178 6480464 Magnesium results in decreased activity of DNMT1 protein CTD PMID:16037419 magnesium atom multiple interactions ISO RGD:1354178 6480464 Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein] CTD PMID:16037419 methamphetamine decreases expression ISO RGD:620979 6480464 Methamphetamine results in decreased expression of DNMT1 mRNA CTD PMID:17254711 methamphetamine increases expression ISO RGD:620979 6480464 Methamphetamine results in increased expression of DNMT1 mRNA CTD PMID:17254711 methyl methanesulfonate decreases expression ISO RGD:1354178 6480464 Methyl Methanesulfonate results in decreased expression of DNMT1 protein CTD PMID:11912126 methyl methanesulfonate increases degradation ISO RGD:1354178 6480464 Methyl Methanesulfonate results in increased degradation of DNMT1 protein CTD PMID:11912126 methylarsonic acid decreases expression ISO RGD:620979 6480464 monomethylarsonic acid results in decreased expression of DNMT1 mRNA CTD PMID:17481689 methylmercury chloride decreases expression ISO RGD:620979 6480464 methylmercuric chloride results in decreased expression of DNMT1 mRNA CTD PMID:19636072 methylmercury chloride increases expression ISO RGD:1354178 6480464 methylmercuric chloride results in increased expression of DNMT1 protein CTD PMID:33454822 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of DNMT1 protein CTD PMID:33454822 mitomycin C decreases expression EXP 6480464 Mitomycin results in decreased expression of DNMT1 protein CTD PMID:27032448 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of DNMT1 mRNA CTD PMID:22401849 morphine increases expression EXP 6480464 Morphine results in increased expression of DNMT1 mRNA CTD PMID:33891991 myricetin multiple interactions ISO RGD:1354178 6480464 [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 myricetin decreases activity ISO RGD:1354178 6480464 myricetin results in decreased activity of DNMT1 protein CTD PMID:16037419 N-acetyl-L-cysteine multiple interactions ISO RGD:1354178 6480464 [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA more ... CTD PMID:29854080 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1354178 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein] CTD PMID:19417133 , PMID:21150308 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein] CTD PMID:23395981 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of DNMT1 CTD PMID:21154115 N-nitrosodiethylamine multiple interactions ISO RGD:620979 6480464 [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of DNMT1 mRNA CTD PMID:17854601 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of DNMT1 mRNA CTD PMID:19996281 N-nitrosodiethylamine multiple interactions EXP 6480464 AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNMT1 mRNA], RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNMT1 mRNA] CTD PMID:17854601 , PMID:19996281 nickel atom increases expression ISO RGD:1354178 6480464 Nickel results in increased expression of DNMT1 mRNA CTD PMID:25583101 nicotinamide multiple interactions EXP 6480464 Niacinamide affects the reaction [9 more ... CTD PMID:24792773 nicotine multiple interactions ISO RGD:620979 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 nicotine decreases expression ISO RGD:620979 6480464 Nicotine results in decreased expression of DNMT1 mRNA CTD PMID:28555334 okadaic acid multiple interactions ISO RGD:1354178 6480464 Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] CTD PMID:23775084 oxaliplatin multiple interactions ISO RGD:620979 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DNMT1 mRNA CTD PMID:25729387 ozone affects response to substance ISO RGD:1354178 6480464 DNMT1 gene polymorphism affects the susceptibility to Ozone CTD PMID:27219456 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of DNMT1 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1354178 6480464 Acetaminophen results in increased expression of DNMT1 mRNA CTD PMID:22230336 paraquat decreases expression ISO RGD:1354178 6480464 Paraquat results in decreased expression of DNMT1 mRNA, Paraquat results in decreased expression of DNMT1 protein CTD PMID:31189234 pelargonidin decreases expression EXP 6480464 pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of DNMT1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1354178 6480464 perfluorooctane sulfonic acid results in decreased expression of DNMT1 mRNA, perfluorooctane sulfonic acid results in decreased expression of DNMT1 protein CTD PMID:31508952 perfluorooctanoic acid decreases expression ISO RGD:1354178 6480464 perfluorooctanoic acid results in decreased expression of DNMT1 protein CTD PMID:26879310 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of DNMT1 mRNA CTD PMID:32320774 perfluorooctanoic acid multiple interactions EXP 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 phenobarbital increases expression ISO RGD:620979 6480464 Phenobarbital results in increased expression of DNMT1 mRNA, Phenobarbital results in increased expression of DNMT1 protein CTD PMID:25247799 , PMID:30141584 phenobarbital decreases expression ISO RGD:620979 6480464 Phenobarbital results in decreased expression of DNMT1 protein CTD PMID:28495587 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of DNMT1 mRNA CTD PMID:19482888 , PMID:23091169 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of DNMT1 protein CTD PMID:22581815 PhIP multiple interactions ISO RGD:620979 6480464 [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA CTD PMID:12097258 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1354178 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein more ... CTD PMID:23775084 piperonyl butoxide increases expression ISO RGD:620979 6480464 Piperonyl Butoxide results in increased expression of DNMT1 mRNA CTD PMID:22484513 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of DNMT1 mRNA CTD PMID:17426115 pirinixic acid decreases expression ISO RGD:620979 6480464 pirinixic acid results in decreased expression of DNMT1 protein CTD PMID:18639561 piroxicam increases expression ISO RGD:1354178 6480464 Piroxicam results in increased expression of DNMT1 mRNA CTD PMID:21858171 poly(I:C) multiple interactions ISO RGD:1354178 6480464 [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA, [Arsenicals co-treated with Poly I-C] results in increased expression of DNMT1 mRNA CTD PMID:34303791 procyanidin B2 increases expression ISO RGD:1354178 6480464 procyanidin B2 results in increased expression of DNMT1 mRNA CTD PMID:25839702 pterostilbene multiple interactions ISO RGD:1354178 6480464 [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT1 mRNA CTD PMID:26459286 Pyridostigmine bromide decreases expression ISO RGD:1354178 6480464 Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA CTD PMID:31175926 Pyridostigmine bromide multiple interactions ISO RGD:1354178 6480464 SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA] CTD PMID:31175926 quercetin multiple interactions ISO RGD:1354178 6480464 [Quercetin co-treated with COMT protein] results in decreased activity of DNMT1 protein more ... CTD PMID:16037419 , PMID:27132804 quercetin increases activity ISO RGD:1354178 6480464 Quercetin results in increased activity of DNMT1 protein CTD PMID:27132804 quercetin increases expression ISO RGD:1354178 6480464 Quercetin results in increased expression of DNMT1 mRNA CTD PMID:21632981 quercetin decreases expression ISO RGD:1354178 6480464 Quercetin results in decreased expression of DNMT1 mRNA CTD PMID:20596804 quinoline multiple interactions ISO RGD:1354178 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein] CTD PMID:19417133 quinoline increases degradation ISO RGD:1354178 6480464 quinoline analog results in increased degradation of DNMT1 protein CTD PMID:19417133 quinoline decreases activity EXP 6480464 quinoline analog results in decreased activity of DNMT1 protein CTD PMID:19417133 resveratrol multiple interactions ISO RGD:620979 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter]] CTD PMID:24136580 resveratrol decreases expression ISO RGD:1354178 6480464 resveratrol results in decreased expression of DNMT1 mRNA, resveratrol results in decreased expression of DNMT1 protein CTD PMID:21801466 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of DNMT1 protein CTD PMID:25505154 resveratrol multiple interactions ISO RGD:1354178 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of DNMT1 mRNA more ... CTD PMID:19167446 more ... rosmarinic acid decreases expression ISO RGD:1354178 6480464 rosmarinic acid results in decreased expression of DNMT1 protein CTD PMID:21078381 S-adenosyl-L-homocysteine decreases activity ISO RGD:1354178 6480464 S-Adenosylhomocysteine results in decreased activity of DNMT1 protein CTD PMID:16037419 S-adenosyl-L-homocysteine multiple interactions EXP 6480464 S-Adenosylhomocysteine inhibits the reaction [DNMT1 protein binds to OGG1 promoter] CTD PMID:22064374 S-adenosyl-L-homocysteine decreases activity EXP 6480464 S-Adenosylhomocysteine results in decreased activity of DNMT1 protein CTD PMID:22064374 S-adenosyl-L-methioninate multiple interactions ISO RGD:1354178 6480464 S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]], S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT1 protein] CTD PMID:22558281 S-adenosyl-L-methionine multiple interactions ISO RGD:1354178 6480464 S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]], S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT1 protein] CTD PMID:22558281 selenium atom affects activity ISO RGD:620979 6480464 Selenium affects the activity of DNMT1 protein CTD PMID:16632891 silicon dioxide multiple interactions ISO RGD:1354178 6480464 DNMT1 protein promotes the reaction [Silicon Dioxide results in increased methylation of PARP1 promoter] CTD PMID:22265868 sinefungin decreases activity ISO RGD:1354178 6480464 sinefungin results in decreased activity of DNMT1 protein CTD PMID:23671287 sirolimus multiple interactions ISO RGD:1354178 6480464 [fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA CTD PMID:19016759 sodium arsenite multiple interactions ISO RGD:1354178 6480464 [sodium arsenite co-treated with Estradiol] results in decreased expression of DNMT1 mRNA more ... CTD PMID:22952798 more ... sodium arsenite increases expression ISO RGD:1354178 6480464 sodium arsenite results in increased expression of DNMT1 mRNA, sodium arsenite results in increased expression of DNMT1 protein CTD PMID:31150806 more ... sodium arsenite multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA CTD PMID:20978746 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of DNMT1 mRNA CTD PMID:17558810 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of DNMT1 mRNA CTD PMID:19822182 sodium arsenite decreases expression ISO RGD:1354178 6480464 sodium arsenite results in decreased expression of DNMT1 mRNA, sodium arsenite results in decreased expression of DNMT1 protein CTD PMID:17107663 more ... sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of DNMT1 mRNA CTD PMID:27862939 Soman decreases expression ISO RGD:620979 6480464 Soman results in decreased expression of DNMT1 mRNA CTD PMID:19281266 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA more ... CTD PMID:28422052 , PMID:29127188 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of DNMT1 mRNA CTD PMID:28422052 sulforaphane decreases expression ISO RGD:1354178 6480464 sulforaphane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 sulforaphane multiple interactions ISO RGD:1354178 6480464 sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT1 mRNA], sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA] CTD PMID:30684530 T-2 toxin increases expression ISO RGD:620979 6480464 T-2 Toxin results in increased expression of DNMT1 mRNA, T-2 Toxin results in increased expression of DNMT1 protein CTD PMID:31279042 tamoxifen multiple interactions EXP 6480464 [arsenic trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA, [arsenic trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 temozolomide increases expression ISO RGD:1354178 6480464 Temozolomide results in increased expression of DNMT1 mRNA CTD PMID:31758290 testosterone multiple interactions ISO RGD:1354178 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT1 mRNA CTD PMID:21592394 testosterone multiple interactions ISO RGD:620979 6480464 [Testosterone co-treated with vinclozolin] results in increased expression of DNMT1 mRNA, Testosterone inhibits the reaction [vinclozolin results in decreased expression of DNMT1 mRNA] CTD PMID:20056826 testosterone decreases expression ISO RGD:1354178 6480464 Testosterone results in decreased expression of DNMT1 mRNA CTD PMID:21592394 tetrachloromethane increases expression ISO RGD:620979 6480464 Carbon Tetrachloride results in increased expression of DNMT1 mRNA, Carbon Tetrachloride results in increased expression of DNMT1 protein CTD PMID:22841775 more ... tetrachloromethane multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of DNMT1 mRNA CTD PMID:30517762 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of DNMT1 mRNA CTD PMID:27339419 , PMID:31919559 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of DNMT1 protein CTD PMID:24648495 thioacetamide increases expression ISO RGD:620979 6480464 Thioacetamide results in increased expression of DNMT1 mRNA CTD PMID:34492290 topotecan decreases expression ISO RGD:620979 6480464 Topotecan results in decreased expression of DNMT1 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:620979 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DNMT1 mRNA CTD PMID:25729387 Tributyltin oxide increases phosphorylation EXP 6480464 bis(tri-n-butyltin)oxide results in increased phosphorylation of DNMT1 protein CTD PMID:22174045 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of DNMT1 mRNA, Trichloroethylene results in increased expression of DNMT1 protein CTD PMID:22407948 , PMID:25549359 triclosan decreases expression ISO RGD:1354178 6480464 Triclosan results in decreased expression of DNMT1 mRNA, Triclosan results in decreased expression of DNMT1 protein CTD PMID:26970259 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of DNMT1 mRNA CTD PMID:19042947 trimethylarsine oxide decreases expression ISO RGD:620979 6480464 trimethylarsine oxide results in decreased expression of DNMT1 mRNA CTD PMID:17481689 triptonide affects expression EXP 6480464 triptonide affects the expression of DNMT1 mRNA CTD PMID:33045310 troglitazone decreases expression ISO RGD:1354178 6480464 troglitazone results in decreased expression of DNMT1 mRNA CTD PMID:19140230 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of DNMT1 mRNA CTD PMID:28973697 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of DNMT1 mRNA CTD PMID:30912803 uranium atom increases expression ISO RGD:620979 6480464 Uranium results in increased expression of DNMT1 mRNA CTD PMID:29024790 valproic acid decreases expression ISO RGD:620979 6480464 Valproic Acid results in decreased expression of DNMT1 mRNA CTD PMID:29427782 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of DNMT1 mRNA CTD PMID:18930951 vinclozolin multiple interactions ISO RGD:620979 6480464 [Testosterone co-treated with vinclozolin] results in increased expression of DNMT1 mRNA, Testosterone inhibits the reaction [vinclozolin results in decreased expression of DNMT1 mRNA] CTD PMID:20056826 vinclozolin increases expression ISO RGD:620979 6480464 vinclozolin results in increased expression of DNMT1 mRNA CTD PMID:23034163 vinclozolin decreases expression ISO RGD:620979 6480464 vinclozolin results in decreased expression of DNMT1 mRNA, vinclozolin results in decreased expression of DNMT1 protein CTD PMID:18042343 , PMID:20056826 vitamin E increases expression ISO RGD:1354178 6480464 Vitamin E results in increased expression of DNMT1 mRNA CTD PMID:29854080 withaferin A decreases expression ISO RGD:1354178 6480464 withaferin A results in decreased expression of DNMT1 mRNA, withaferin A results in decreased expression of DNMT1 protein CTD PMID:23593078 zearalenone increases expression ISO RGD:1354178 6480464 Zearalenone results in increased expression of DNMT1 mRNA CTD PMID:32119988
