Dnmt1 (DNA methyltransferase (cytosine-5) 1) - Rat Genome Database

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Gene: Dnmt1 (DNA methyltransferase (cytosine-5) 1) Mus musculus
Analyze
Symbol: Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
RGD ID: 1552151
MGI Page MGI
Description: Enables several functions, including DNA (cytosine-5-)-methyltransferase activity; nucleic acid binding activity; and zinc ion binding activity. Involved in DNA methylation-dependent heterochromatin assembly and maintenance of DNA methylation. Acts upstream of or within several processes, including DNA methylation; cellular response to bisphenol A; and negative regulation of macromolecule metabolic process. Located in nucleus; pericentric heterochromatin; and replication fork. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Graves' disease; autosomal dominant cerebellar ataxia, deafness and narcolepsy; hereditary sensory neuropathy; hereditary sensory neuropathy type 1E; and lung non-small cell carcinoma. Orthologous to human DNMT1 (DNA methyltransferase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cxxc9; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase MmuI; DNA MTase MmuI; Dnmt; Dnmt1o; m.MmuI; MCMT; Met-1; Met1; MommeD; MommeD2; MTa; MTase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,818,501 - 20,871,184 (-)NCBIGRCm39mm39
GRCm39 Ensembl920,818,505 - 20,871,184 (-)Ensembl
GRCm38920,907,206 - 20,959,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,907,209 - 20,959,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,711,653 - 20,757,317 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,657,611 - 20,703,267 (-)NCBImm8
Celera918,175,907 - 18,221,569 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
Alcoholic Fatty Liver  (IMP)
alopecia areata  (ISO)
anxiety disorder  (ISO)
asthma  (IEP,ISO)
Ataxia  (ISO)
autoimmune disease  (IMP)
autosomal dominant cerebellar ataxia, deafness and narcolepsy  (ISO)
Beckwith-Wiedemann syndrome  (ISO)
Binge Drinking  (IEP)
Brain Injuries  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
Carcinogenesis  (ISO)
carcinoma  (ISO)
cardiomyopathy  (IEP)
cerebellar ataxia  (ISO)
Charcot-Marie-Tooth disease  (ISO)
choline deficiency disease  (ISO)
chronic myeloid leukemia  (ISO)
clear cell renal cell carcinoma  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
dementia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
endometriosis of uterus  (ISO)
Experimental Arthritis  (ISO)
Fetal Growth Retardation  (ISO)
Graves' disease  (ISO)
Hearing Loss  (ISO)
hepatocellular carcinoma  (ISO)
hereditary sensory neuropathy  (ISO)
hereditary sensory neuropathy type 1E  (ISO)
Hyperalgesia  (ISO)
hypertrophic cardiomyopathy  (ISO)
liver cirrhosis  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
medulloblastoma  (ISO)
meningioma  (ISO)
middle cerebral artery infarction  (IMP)
mucoepidermoid carcinoma  (ISO)
myelodysplastic syndrome  (ISO)
Neoplasm Invasiveness  (ISO)
Oral Lichen Planus  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic ductal carcinoma  (ISO)
Pancreatic Intraepithelial Neoplasia  (ISO)
Peritoneal Fibrosis  (ISO)
Pituitary Stalk Interruption Syndrome  (ISO)
prostate adenocarcinoma  (IEP)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
Prostatic Neoplasms  (IEP,IMP,ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (IDA,ISO)
sleep disorder  (ISO)
spastic ataxia  (ISO)
Stomach Neoplasms  (ISO)
systemic lupus erythematosus  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
3,3'-diindolylmethane  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-(hydroxymethyl)cytosine  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
6-prenylnaringenin  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
8-hydroxy-2'-deoxyguanosine  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acetic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
amitriptyline  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzophenanthridine  (ISO)
berberine  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (ISO)
buta-1,3-diene  (EXP)
butyric acid  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calciol  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (EXP)
casticin  (ISO)
choline  (EXP)
chromium atom  (EXP)
cisplatin  (ISO)
citalopram  (ISO)
cladribine  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
DDE  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
Difenacoum  (ISO)
dihydro-beta-erythroidine  (ISO)
dimethyl sulfate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
etoposide  (ISO)
fenvalerate  (ISO)
fisetin  (ISO)
Flocoumafen  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fulvestrant  (EXP,ISO)
fumonisin B1  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glucaric acid  (EXP)
glucose  (ISO)
glycine betaine  (EXP)
glycitein  (ISO)
glycitin  (ISO)
glyphosate  (ISO)
guggulsterone  (ISO)
hexadecanoic acid  (ISO)
hexane  (ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyurea  (ISO)
hypochlorous acid  (EXP)
ionomycin  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
leptomycin B  (ISO)
linsidomine  (ISO)
magnesium atom  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (EXP,ISO)
mitomycin C  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
morphine  (EXP)
myricetin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nicotinamide  (EXP)
nicotine  (ISO)
okadaic acid  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pelargonidin  (EXP)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
PhIP  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
poly(I:C)  (ISO)
procyanidin B2  (ISO)
pterostilbene  (ISO)
Pyridostigmine bromide  (ISO)
quercetin  (ISO)
quinoline  (EXP,ISO)
resveratrol  (EXP,ISO)
rosmarinic acid  (ISO)
S-adenosyl-L-homocysteine  (EXP,ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sinefungin  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
Soman  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (EXP)
trimethylarsine oxide  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
tungsten  (EXP)
uranium atom  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vitamin E  (ISO)
withaferin A  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
brain development  (ISO)
C-5 methylation of cytosine  (IDA,IEA)
cellular response to amino acid stimulus  (IDA)
cellular response to bisphenol A  (IDA)
cellular response to lead ion  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
chromatin organization  (IEA)
DNA hypermethylation  (ISO)
DNA methylation  (IDA,IGI,IMP)
DNA methylation involved in embryo development  (IGI,IMP)
DNA methylation on cytosine  (IMP,ISO)
DNA methylation on cytosine within a CG sequence  (ISO)
DNA methylation-dependent heterochromatin assembly  (IDA)
maintenance of DNA methylation  (IMP,ISO)
methylation  (IEA)
negative regulation of gene expression  (IMP,ISO)
negative regulation of histone H3-K9 methylation  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,IMP)
negative regulation of transcription, DNA-templated  (IMP)
negative regulation of vascular associated smooth muscle cell apoptotic process  (ISO)
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching  (ISO)
neuron differentiation  (ISO)
positive regulation of DNA methylation-dependent heterochromatin assembly  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of histone H3-K4 methylation  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
Ras protein signal transduction  (ISO)
regulation of cell population proliferation  (IGI)
regulation of gene expression  (IMP)
response to activity  (ISO)
response to caffeine  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to heat  (ISO)
response to ionizing radiation  (ISO)
response to lead ion  (ISO)
response to lipopolysaccharide  (ISO)
response to nutrient levels  (ISO)
response to organic substance  (ISO)
response to testosterone  (ISO)
response to toxic substance  (ISO)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)
S-adenosylmethionine metabolic process  (ISO)
transcription, DNA-templated  (IMP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
PMID:1606615   PMID:1628623   PMID:3210246   PMID:4052092   PMID:7537636   PMID:7557385   PMID:7635139   PMID:7739908   PMID:8026645   PMID:8247133   PMID:8608936   PMID:8896980  
PMID:8898232   PMID:8917520   PMID:8940105   PMID:9160753   PMID:9211941   PMID:9278500   PMID:9358180   PMID:9449671   PMID:9679064   PMID:9771701   PMID:9794235   PMID:9830015  
PMID:9887097   PMID:10349636   PMID:10495277   PMID:10615135   PMID:10708765   PMID:10715201   PMID:10831840   PMID:10888872   PMID:10919675   PMID:10950864   PMID:10985851   PMID:11024297  
PMID:11042159   PMID:11063128   PMID:11076861   PMID:11137995   PMID:11157065   PMID:11290321   PMID:11382789   PMID:11399088   PMID:11728338   PMID:11820819   PMID:11884600   PMID:11888894  
PMID:11940649   PMID:11942627   PMID:11977983   PMID:12071960   PMID:12354094   PMID:12397175   PMID:12477932   PMID:12520002   PMID:12538347   PMID:12546714   PMID:12606374   PMID:12702868  
PMID:12702876   PMID:12799438   PMID:12829028   PMID:12904583   PMID:14511672   PMID:14519686   PMID:14595437   PMID:14610273   PMID:14612500   PMID:14681479   PMID:14749379   PMID:14761969  
PMID:14978102   PMID:15063176   PMID:15215866   PMID:15289832   PMID:15310660   PMID:15317747   PMID:15326356   PMID:15339928   PMID:15378011   PMID:15380515   PMID:15383570   PMID:15456861  
PMID:15486983   PMID:15489334   PMID:15509869   PMID:15516931   PMID:15522198   PMID:15533817   PMID:15550930   PMID:15618518   PMID:15634679   PMID:15671176   PMID:15735669   PMID:15782199  
PMID:15890782   PMID:15899874   PMID:15919778   PMID:15956212   PMID:15975555   PMID:16014513   PMID:16014911   PMID:16085498   PMID:16086268   PMID:16120212   PMID:16141072   PMID:16141073  
PMID:16174748   PMID:16226703   PMID:16283622   PMID:16288735   PMID:16329111   PMID:16424344   PMID:16491076   PMID:16565708   PMID:16585546   PMID:16602821   PMID:16606618   PMID:16824199  
PMID:16887828   PMID:16887963   PMID:16940357   PMID:17030625   PMID:17046852   PMID:17182866   PMID:17245608   PMID:17296936   PMID:17311920   PMID:17353267   PMID:17371843   PMID:17450140  
PMID:17576694   PMID:17621273   PMID:17673620   PMID:17682057   PMID:17893328   PMID:17931718   PMID:17967808   PMID:17982445   PMID:17989773   PMID:17994007   PMID:18048024   PMID:18157120  
PMID:18202356   PMID:18221528   PMID:18241125   PMID:18252747   PMID:18276606   PMID:18452947   PMID:18536344   PMID:18536530   PMID:18559477   PMID:18563322   PMID:18599511   PMID:18616936  
PMID:18667590   PMID:18784354   PMID:18799693   PMID:18845137   PMID:18852456   PMID:18922972   PMID:18977197   PMID:19098913   PMID:19109157   PMID:19155313   PMID:19262751   PMID:19433415  
PMID:19454658   PMID:19715692   PMID:19796624   PMID:19801979   PMID:19923434   PMID:20059948   PMID:20059953   PMID:20192920   PMID:20200229   PMID:20211142   PMID:20212170   PMID:20228804  
PMID:20300987   PMID:20348135   PMID:20352123   PMID:20387133   PMID:20404320   PMID:20412781   PMID:20418885   PMID:20439742   PMID:20489138   PMID:20547750   PMID:20548288   PMID:20573497  
PMID:20573698   PMID:20587527   PMID:20613874   PMID:20622006   PMID:20889571   PMID:21057543   PMID:21092094   PMID:21163962   PMID:21233130   PMID:21268065   PMID:21296890   PMID:21311766  
PMID:21321201   PMID:21354127   PMID:21362628   PMID:21383065   PMID:21427230   PMID:21452232   PMID:21459093   PMID:21492995   PMID:21497756   PMID:21518897   PMID:21518972   PMID:21553025  
PMID:21593412   PMID:21624812   PMID:21677750   PMID:21731673   PMID:21828137   PMID:21873635   PMID:21905163   PMID:21980391   PMID:21980460   PMID:22064703   PMID:22090490   PMID:22094255  
PMID:22134929   PMID:22269950   PMID:22323818   PMID:22345515   PMID:22349820   PMID:22354994   PMID:22362755   PMID:22445894   PMID:22559742   PMID:22580371   PMID:22641038   PMID:22722331  
PMID:22763785   PMID:22784989   PMID:22795133   PMID:22842467   PMID:22898819   PMID:22967183   PMID:22969435   PMID:23028046   PMID:23085235   PMID:23086144   PMID:23171847   PMID:23302691  
PMID:23325669   PMID:23393137   PMID:23406904   PMID:23431054   PMID:23453809   PMID:23463006   PMID:23535145   PMID:23548937   PMID:23554223   PMID:23576758   PMID:23636699   PMID:23641003  
PMID:23687305   PMID:23754744   PMID:23760957   PMID:23825703   PMID:23866265   PMID:23897429   PMID:23918800   PMID:23920106   PMID:23995786   PMID:24001767   PMID:24013172   PMID:24021675  
PMID:24025402   PMID:24027299   PMID:24105743   PMID:24183668   PMID:24253042   PMID:24278026   PMID:24335282   PMID:24362762   PMID:24368767   PMID:24371119   PMID:24457600   PMID:24586322  
PMID:24599782   PMID:24637118   PMID:24782312   PMID:24924148   PMID:24944101   PMID:24952961   PMID:25092339   PMID:25136103   PMID:25300248   PMID:25389311   PMID:25446526   PMID:25487288  
PMID:25496779   PMID:25533200   PMID:25561507   PMID:25578964   PMID:25659757   PMID:25662615   PMID:25680957   PMID:25820252   PMID:25892014   PMID:25908435   PMID:25939752   PMID:25982413  
PMID:26023099   PMID:26030024   PMID:26098213   PMID:26139044   PMID:26241757   PMID:26339596   PMID:26383849   PMID:26482727   PMID:26553800   PMID:26573818   PMID:26576615   PMID:26592967  
PMID:26602018   PMID:26606905   PMID:26751286   PMID:26808831   PMID:26921474   PMID:26999257   PMID:27003684   PMID:27122033   PMID:27149841   PMID:27151458   PMID:27240213   PMID:27251626  
PMID:27488808   PMID:27516062   PMID:27545441   PMID:27618282   PMID:27681438   PMID:27693117   PMID:27713144   PMID:27752090   PMID:27824296   PMID:27826835   PMID:27841881   PMID:27865785  
PMID:27882346   PMID:27886214   PMID:27892467   PMID:27895551   PMID:27956497   PMID:28069743   PMID:28106784   PMID:28119131   PMID:28173052   PMID:28190767   PMID:28215845   PMID:28317850  
PMID:28318634   PMID:28334952   PMID:28369487   PMID:28378742   PMID:28406523   PMID:28447752   PMID:28451635   PMID:28472596   PMID:28564603   PMID:28614801   PMID:28671696   PMID:28709638  
PMID:28842251   PMID:28919262   PMID:28924038   PMID:28928282   PMID:28943313   PMID:29027601   PMID:29100015   PMID:29117290   PMID:29145563   PMID:29146735   PMID:29164502   PMID:29191807  
PMID:29445148   PMID:29471350   PMID:29482658   PMID:29513653   PMID:29522357   PMID:29551912   PMID:29673587   PMID:29691401   PMID:29700293   PMID:29912614   PMID:29955131   PMID:29970123  
PMID:30061411   PMID:30140294   PMID:30186101   PMID:30190513   PMID:30232292   PMID:30307477   PMID:30341171   PMID:30392929   PMID:30457570   PMID:30487604   PMID:30518531   PMID:30530687  
PMID:30659795   PMID:30659837   PMID:30850438   PMID:30975723   PMID:31001916   PMID:31040226   PMID:31104361   PMID:31142766   PMID:31154022   PMID:31162944   PMID:31182635   PMID:31209294  
PMID:31242446   PMID:31285763   PMID:31361780   PMID:31530896   PMID:31558711   PMID:31748268   PMID:31959742   PMID:32061563   PMID:32123907   PMID:32144273   PMID:32147726   PMID:32222282  
PMID:32325033   PMID:32514790   PMID:32561758   PMID:32667642   PMID:32690947   PMID:32709850   PMID:32751461   PMID:32819567   PMID:32892421   PMID:32961871   PMID:33205075   PMID:33259831  
PMID:33310192   PMID:33483902   PMID:33670788   PMID:33836591   PMID:33998651   PMID:34140676   PMID:34161765   PMID:34166371   PMID:34362460   PMID:34504806   PMID:34516921   PMID:34533678  
PMID:34586646   PMID:34815492   PMID:34824202   PMID:34903641   PMID:34986190   PMID:34990407   PMID:35486848  


Genomics

Comparative Map Data
Dnmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,818,501 - 20,871,184 (-)NCBIGRCm39mm39
GRCm39 Ensembl920,818,505 - 20,871,184 (-)Ensembl
GRCm38920,907,206 - 20,959,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,907,209 - 20,959,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,711,653 - 20,757,317 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,657,611 - 20,703,267 (-)NCBImm8
Celera918,175,907 - 18,221,569 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.66NCBI
DNMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,133,346 - 10,194,953 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1910,133,342 - 10,231,286 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,244,022 - 10,305,629 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,105,022 - 10,166,811 (-)NCBINCBI36hg18NCBI36
Build 341910,105,022 - 10,166,811NCBI
Celera1910,139,454 - 10,201,147 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,824,670 - 9,886,268 (-)NCBIHuRef
CHM1_11910,244,307 - 10,306,021 (-)NCBICHM1_1
T2T-CHM13v2.01910,259,569 - 10,321,116 (-)NCBI
Dnmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,440,611 - 19,486,659 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl819,440,611 - 19,486,659 (-)Ensembl
Rnor_6.0821,922,515 - 21,968,495 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,922,515 - 21,968,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0821,978,830 - 22,024,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,926,995 - 19,973,256 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1819,927,666 - 19,973,220 (-)NCBI
Celera820,835,612 - 20,881,380 (-)NCBICelera
Cytogenetic Map8q13NCBI
Dnmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,465,480 - 1,505,462 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,465,529 - 1,505,379 (-)NCBIChiLan1.0ChiLan1.0
DNMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11910,342,478 - 10,390,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,342,478 - 10,406,972 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0199,681,847 - 9,745,334 (-)NCBIMhudiblu_PPA_v0panPan3
DNMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,872,213 - 50,928,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,879,527 - 50,928,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,741,748 - 50,797,884 (+)NCBI
ROS_Cfam_1.02051,393,895 - 51,450,128 (+)NCBI
ROS_Cfam_1.0 Ensembl2051,401,720 - 51,450,127 (+)Ensembl
UMICH_Zoey_3.12050,599,735 - 50,657,798 (+)NCBI
UNSW_CanFamBas_1.02051,028,945 - 51,085,072 (+)NCBI
UU_Cfam_GSD_1.02051,269,676 - 51,325,956 (+)NCBI
Dnmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,789,213 - 209,834,531 (+)NCBI
SpeTri2.0NW_004936659520,181 - 565,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl268,981,564 - 69,029,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1268,981,564 - 69,040,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,309,511 - 69,357,838 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,199,006 - 9,263,890 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl69,199,003 - 9,263,607 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607410,795,260 - 10,857,063 (+)NCBIVero_WHO_p1.0
Dnmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,315,251 - 2,358,711 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248282,316,042 - 2,358,866 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,926,456 - 20,926,554UniSTSGRCm38
MGSCv37920,730,900 - 20,730,998UniSTSGRCm37
Celera918,195,154 - 18,195,252UniSTS
Cytogenetic Map9A3UniSTS
cM Map95.0UniSTS
PMC133764P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,941,343 - 20,941,681UniSTSGRCm38
MGSCv37920,745,787 - 20,746,125UniSTSGRCm37
Celera918,210,039 - 18,210,377UniSTS
Cytogenetic Map9A3UniSTS
cM Map95.0UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,926,651 - 20,926,828UniSTSGRCm38
MGSCv37920,731,095 - 20,731,272UniSTSGRCm37
Celera918,195,349 - 18,195,526UniSTS
Cytogenetic Map9A3UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
cM Map95.0UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
cM Map95.0UniSTS
Dnmt1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,923,754 - 20,924,131UniSTSGRCm38
MGSCv37920,728,198 - 20,728,575UniSTSGRCm37
Celera918,192,452 - 18,192,829UniSTS
Cytogenetic Map9A3UniSTS
cM Map95.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000122211296Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir185mmu-miR-185-5pOncomiRDBexternal_infoNANA21962230
Mir185mmu-miR-185-5pOncomiRDBexternal_infoNANA23318422
Mir342mmu-miR-342-3pOncomiRDBexternal_infoNANA21565830
Mir152mmu-miR-152-3pOncomiRDBexternal_infoNANA23318422
Mir152mmu-miR-152-3pOncomiRDBexternal_infoNANA22935141
Mir152mmu-miR-152-3pOncomiRDBexternal_infoNANA20841484
Mir152mmu-miR-152-3pOncomiRDBexternal_infoNANA20578129
Mir152mmu-miR-152-3pOncomiRDBexternal_infoNANA20146264
Mir148ammu-miR-148a-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23532995
Mir148ammu-miR-148a-3pOncomiRDBexternal_infoNANA22935141
Mir148ammu-miR-148a-3pOncomiRDBexternal_infoNANA20146264
Mir140mmu-miR-140-3pOncomiRDBexternal_infoNANA22898998

Predicted Target Of
Summary Value
Count of predictions:291
Count of miRNA genes:88
Interacting mature miRNAs:92
Transcripts:ENSMUST00000004202, ENSMUST00000177754, ENSMUST00000178110
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001199431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001314011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC170598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF036007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF036008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF036009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF162282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF175432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK636383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U70051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X14805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X77486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000004202   ⟹   ENSMUSP00000004202
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,818,505 - 20,864,275 (-)Ensembl
GRCm38.p6 Ensembl920,907,209 - 20,952,979 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177754   ⟹   ENSMUSP00000136982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,818,505 - 20,871,184 (-)Ensembl
GRCm38.p6 Ensembl920,907,209 - 20,959,888 (-)Ensembl
RefSeq Acc Id: ENSMUST00000178110   ⟹   ENSMUSP00000136669
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,818,505 - 20,863,919 (-)Ensembl
GRCm38.p6 Ensembl920,907,209 - 20,952,623 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214964
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,818,514 - 20,820,275 (-)Ensembl
GRCm38.p6 Ensembl920,907,218 - 20,908,979 (-)Ensembl
RefSeq Acc Id: ENSMUST00000215545
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,840,387 - 20,864,141 (-)Ensembl
GRCm38.p6 Ensembl920,929,091 - 20,952,845 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,843,491 - 20,848,485 (-)Ensembl
GRCm38.p6 Ensembl920,932,195 - 20,937,189 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216540   ⟹   ENSMUSP00000150433
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,818,817 - 20,863,901 (-)Ensembl
GRCm38.p6 Ensembl920,907,521 - 20,952,605 (-)Ensembl
RefSeq Acc Id: NM_001199431   ⟹   NP_001186360
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,502 - 20,864,275 (-)NCBI
GRCm38920,907,206 - 20,952,979 (-)NCBI
Celera918,175,904 - 18,228,582 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199432   ⟹   NP_001186361
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,502 - 20,871,184 (-)NCBI
GRCm38920,907,206 - 20,959,888 (-)NCBI
Celera918,175,904 - 18,228,582 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199433   ⟹   NP_001186362
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,502 - 20,863,919 (-)NCBI
GRCm38920,907,206 - 20,952,623 (-)NCBI
Celera918,175,904 - 18,228,582 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001314011   ⟹   NP_001300940
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,502 - 20,864,275 (-)NCBI
GRCm38920,907,206 - 20,952,979 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010066   ⟹   NP_034196
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,502 - 20,864,275 (-)NCBI
GRCm38920,907,206 - 20,952,979 (-)NCBI
MGSCv37920,711,653 - 20,757,317 (-)RGD
Celera918,175,904 - 18,228,582 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509988   ⟹   XP_006510051
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,501 - 20,864,270 (-)NCBI
GRCm38920,907,209 - 20,952,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242393   ⟹   XP_011240695
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,818,501 - 20,863,856 (-)NCBI
GRCm38920,907,209 - 20,951,909 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001186360 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186361 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186362 (Get FASTA)   NCBI Sequence Viewer  
  NP_001300940 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391614 (Get FASTA)   NCBI Sequence Viewer  
  NP_034196 (Get FASTA)   NCBI Sequence Viewer  
  XP_006510051 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240695 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40061 (Get FASTA)   NCBI Sequence Viewer  
  AAC52900 (Get FASTA)   NCBI Sequence Viewer  
  AAC53551 (Get FASTA)   NCBI Sequence Viewer  
  AAF19352 (Get FASTA)   NCBI Sequence Viewer  
  AAF60965 (Get FASTA)   NCBI Sequence Viewer  
  AAF97695 (Get FASTA)   NCBI Sequence Viewer  
  AAH48148 (Get FASTA)   NCBI Sequence Viewer  
  AAH53047 (Get FASTA)   NCBI Sequence Viewer  
  AAI19484 (Get FASTA)   NCBI Sequence Viewer  
  BAB28743 (Get FASTA)   NCBI Sequence Viewer  
  BAE22880 (Get FASTA)   NCBI Sequence Viewer  
  BAE25447 (Get FASTA)   NCBI Sequence Viewer  
  BAE27713 (Get FASTA)   NCBI Sequence Viewer  
  CAA32910 (Get FASTA)   NCBI Sequence Viewer  
  EDL25139 (Get FASTA)   NCBI Sequence Viewer  
  EDL25140 (Get FASTA)   NCBI Sequence Viewer  
  EDL25141 (Get FASTA)   NCBI Sequence Viewer  
  EDL25142 (Get FASTA)   NCBI Sequence Viewer  
  EDL25143 (Get FASTA)   NCBI Sequence Viewer  
  EDL25144 (Get FASTA)   NCBI Sequence Viewer  
  EDL25145 (Get FASTA)   NCBI Sequence Viewer  
  P13864 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_034196   ⟸   NM_010066
- Peptide Label: isoform 2
- UniProtKB: P13864 (UniProtKB/Swiss-Prot),   Q3UHZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186361   ⟸   NM_001199432
- Peptide Label: isoform 3
- UniProtKB: P13864 (UniProtKB/Swiss-Prot),   J3QNW0 (UniProtKB/TrEMBL),   Q3UHZ3 (UniProtKB/TrEMBL),   Q3UWN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186360   ⟸   NM_001199431
- Peptide Label: isoform 1
- UniProtKB: P13864 (UniProtKB/Swiss-Prot),   Q3UHZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186362   ⟸   NM_001199433
- Peptide Label: isoform 4
- UniProtKB: P13864 (UniProtKB/Swiss-Prot),   Q3UHZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510051   ⟸   XM_006509988
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011240695   ⟸   XM_011242393
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001300940   ⟸   NM_001314011
- Peptide Label: isoform 5
- UniProtKB: P13864 (UniProtKB/Swiss-Prot),   Q3UHZ3 (UniProtKB/TrEMBL),   Q7TSJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000136669   ⟸   ENSMUST00000178110
RefSeq Acc Id: ENSMUSP00000150433   ⟸   ENSMUST00000216540
RefSeq Acc Id: ENSMUSP00000136982   ⟸   ENSMUST00000177754
RefSeq Acc Id: ENSMUSP00000004202   ⟸   ENSMUST00000004202
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P13864-F1-model_v2 AlphaFold P13864 1-1620 view protein structure

Promoters
RGD ID:6848403
Promoter ID:MM_ACW:49728
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:DNMT1.NSEP07-UNSPLICED,   DNMT1.QSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,712,196 - 20,713,047 (-)MPROMDB
RGD ID:6844433
Promoter ID:MM_KWN:56534
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:UC009OJN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,717,646 - 20,718,297 (-)MPROMDB
RGD ID:6848404
Promoter ID:MM_ACW:49731
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney,   Spleen
Transcripts:DNMT1.MSEP07,   DNMT1.RSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,728,966 - 20,729,466 (-)MPROMDB
RGD ID:6844437
Promoter ID:MM_KWN:56535
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000004202,   NM_010066,   UC009OJO.1,   UC009OJQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,757,071 - 20,757,571 (-)MPROMDB
RGD ID:8668902
Promoter ID:EPDNEW_M12482
Type:multiple initiation site
Name:Dnmt1_2
Description:Mus musculus DNA methyltransferase (cytosine-5) 1 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12483  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38920,952,577 - 20,952,637EPDNEW
RGD ID:8668904
Promoter ID:EPDNEW_M12483
Type:initiation region
Name:Dnmt1_1
Description:Mus musculus DNA methyltransferase (cytosine-5) 1 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12482  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38920,952,817 - 20,952,877EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:94912 AgrOrtholog
Ensembl Genes ENSMUSG00000004099 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000004202 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000136669 UniProtKB/TrEMBL
  ENSMUSP00000136982 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000150433 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000004202 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000177754 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000178110 UniProtKB/TrEMBL
  ENSMUST00000216540 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BAH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAH_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_DNA_meth_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MeTfrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_meth_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cytosine_MeTrfase1_RFD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DMAP1-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CXXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13433 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:94912 ENTREZGENE
NCBI Gene 13433 ENTREZGENE
Pfam BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DMAP_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_methylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT1-RFD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-CXXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnmt1 PhenoGen
PIRSF DNMT1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS C5METTRFRASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MTASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MTASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DMAP1_BIND UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_MT_C5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_CXXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DMAP_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DNMT1_MOUSE UniProtKB/Swiss-Prot
  J3QNW0 ENTREZGENE, UniProtKB/TrEMBL
  P13864 ENTREZGENE
  Q0VDW2_MOUSE UniProtKB/TrEMBL
  Q3UHZ3 ENTREZGENE, UniProtKB/TrEMBL
  Q3UPE8_MOUSE UniProtKB/TrEMBL
  Q3UWN4 ENTREZGENE, UniProtKB/TrEMBL
  Q7TSJ0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P97413 UniProtKB/Swiss-Prot
  Q80ZU3 UniProtKB/Swiss-Prot
  Q9CSC6 UniProtKB/Swiss-Prot
  Q9QXX6 UniProtKB/Swiss-Prot