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Gene: Dnmt1 (DNA methyltransferase (cytosine-5) 1) Mus musculus
Symbol: Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Description: Exhibits several functions, including DNA (cytosine-5-)-methyltransferase activity; nucleic acid binding activity; and zinc ion binding activity. Involved in several processes, including DNA metabolic process; cellular response to amino acid stimulus; and negative regulation of gene expression. Localizes to nucleus; pericentric heterochromatin; and replication fork. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Graves' disease; autosomal dominant cerebellar ataxia, deafness and narcolepsy; hereditary sensory neuropathy; and hereditary sensory neuropathy type 1E. Orthologous to human DNMT1 (DNA methyltransferase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Cxxc9; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase MmuI; DNA MTase MmuI; Dnmt; Dnmt1o; m.MmuI; MCMT; Met-1; Met1; MommeD2; MTase
Homo sapiens (human) : DNMT1 (DNA methyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnmt1 (DNA methyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnmt1 (DNA methyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNMT1 (DNA methyltransferase 1)
Canis lupus familiaris (dog) : DNMT1 (DNA methyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnmt1 (DNA methyltransferase 1)
Sus scrofa (pig) : DNMT1 (DNA methyltransferase 1)
Chlorocebus sabaeus (African green monkey) : DNMT1 (DNA methyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Dnmt1 (DNA methyltransferase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl920,907,209 - 20,959,888 (-)EnsemblGRCm38mm10GRCm38
GRCm38920,907,206 - 20,959,888 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37920,711,653 - 20,757,317 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,657,611 - 20,703,267 (-)NCBImm8
Celera918,175,907 - 18,221,569 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dnmt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552151
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.