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Gene: Ppard (peroxisome proliferator activator receptor delta) Mus musculus
Symbol: Ppard
Name: peroxisome proliferator activator receptor delta
Description: Exhibits DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including animal organ development; keratinocyte migration; and regulation of gene expression. Localizes to nuclear chromatin. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Used to study Huntington's disease and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta); PARTICIPATES IN acute myeloid leukemia pathway; Wnt signaling pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; (S)-naringenin; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mPPAR(delta); Nr1c2; NUC-1; NUC1; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; peroxisome proliferator-activated receptor delta; PPAR-beta; PPAR-delta; PPAR[b]; Pparb; Pparb/d; PPARdelta; PPARdelta/beta
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1728,232,700 - 28,301,474 (+)EnsemblGRCm38mm10GRCm38
GRCm381728,232,754 - 28,301,469 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371728,369,699 - 28,438,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,960,392 - 28,029,058 (+)NCBImm8
Celera1728,786,405 - 28,855,326 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ppard
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731946
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.