Ppard (peroxisome proliferator activator receptor delta) - Rat Genome Database

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Gene: Ppard (peroxisome proliferator activator receptor delta) Mus musculus
Analyze
Symbol: Ppard
Name: peroxisome proliferator activator receptor delta
RGD ID: 731946
MGI Page MGI
Description: Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including negative regulation of myoblast differentiation; positive regulation of skeletal muscle tissue regeneration; and regulation of gene expression. Acts upstream of or within several processes, including keratinocyte migration; keratinocyte proliferation; and positive regulation of phosphatidylinositol 3-kinase signaling. Located in chromatin and nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Used to study Huntington's disease and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta); PARTICIPATES IN acute myeloid leukemia pathway; Wnt signaling pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; (S)-naringenin; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mPPAR(delta); Nr1; Nr1c2; NUC; NUC-1; NUC1; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; P; Peroxisome proliferator-activated receptor beta; peroxisome proliferator-activated receptor delta; Ppa; PPAR; PPAR-beta; PPAR-delta; PPAR[b]; Pparb; Pparb/d; PPARdelta; PPARdelta/beta
RGD Orthologs
Human
Rat
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,451,657 - 28,520,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl1728,451,674 - 28,520,448 (+)Ensembl
GRCm381728,232,754 - 28,301,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,232,700 - 28,301,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,369,699 - 28,438,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,960,392 - 28,029,058 (+)NCBImm8
Celera1728,786,405 - 28,855,326 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(5Z,8Z,11Z,13E)-15-HETE  (EXP)
(S)-naringenin  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1,4-bis(2-ethylhexyl) sulfosuccinate  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-D  (ISO)
2-bromohexadecanoic acid  (EXP,ISO)
2-Ethylhexanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
6-propyl-2-thiouracil  (ISO)
9E,11E-octadecadienoic acid  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-linolenic acid  (EXP,ISO)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimonite  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arachidonic acid  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
aspartame  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bezafibrate  (EXP,ISO)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
butyric acid  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
casticin  (ISO)
celecoxib  (ISO)
CHIR 99021  (EXP)
chlorpyrifos  (ISO)
cilnidipine  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
Clofop  (ISO)
cobalt dichloride  (ISO)
conjugated linoleic acid  (EXP,ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
Di-n-decyl phthalate  (ISO)
Di-n-hexyl phthalate  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
dichloromethane  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diheptyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
Dimethyl phthalate  (ISO)
dipentyl phthalate  (ISO)
dipropyl phthalate  (ISO)
doxorubicin  (ISO)
ellagic acid  (ISO)
enalaprilat dihydrate  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
felodipine  (ISO)
fenofibrate  (EXP,ISO)
fluoranthene  (EXP)
flusilazole  (ISO)
fluvalinate  (ISO)
fructose  (EXP)
furan  (ISO)
gemcitabine  (EXP)
gemfibrozil  (EXP,ISO)
glucose  (ISO)
glyphosate  (ISO)
graphene oxide  (EXP)
griseofulvin  (EXP)
GW 2433  (ISO)
GW 501516  (EXP,ISO)
GW 7647  (ISO)
HET0016  (ISO)
hexadecanoic acid  (ISO)
hydroquinone  (ISO)
idarubicin  (ISO)
imidacloprid  (ISO)
indometacin  (ISO)
isorhamnetin  (ISO)
lacidipine  (ISO)
linoleic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
mithramycin  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (EXP,ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (EXP,ISO)
monohexyl phthalate  (ISO)
Monomethyl phthalate  (ISO)
monooctyl phthalate  (ISO)
monosodium L-glutamate  (EXP)
N-nitrosodiethylamine  (ISO)
nemorubicin  (ISO)
niclosamide  (ISO)
nimesulide  (EXP,ISO)
NMN zwitterion  (EXP)
norathyriol  (ISO)
octanoic acid  (EXP)
okadaic acid  (ISO)
oleic acid  (EXP,ISO)
orlistat  (ISO)
paracetamol  (ISO)
perflubutane  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorohexanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phenylephrine  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phthalic acid  (ISO)
phytanic acid  (ISO)
pioglitazone  (EXP,ISO)
Pirarubicin  (ISO)
pirinixic acid  (EXP,ISO)
pitavastatin  (ISO)
pitavastatin(1-)  (ISO)
prostaglandin E2  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
rebaudioside A  (EXP)
resveratrol  (EXP,ISO)
Ro 41-5253  (ISO)
rotenone  (ISO)
rutin  (ISO)
SB 203580  (ISO)
sirolimus  (EXP)
Sodium oleate  (ISO)
Soman  (ISO)
steviol  (EXP)
stevioside  (EXP)
streptozocin  (EXP,ISO)
sulindac  (EXP,ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
telmisartan  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thiabendazole  (ISO)
titanium dioxide  (EXP)
trichloroethene  (EXP)
triphenylstannane  (ISO)
Triptolide  (EXP)
tunicamycin  (EXP)
tyrphostin AG 1478  (ISO)
urethane  (ISO)
valproic acid  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adipose tissue development  (IMP)
apoptotic process  (ISO)
apoptotic signaling pathway  (ISO)
axon ensheathment  (IMP)
cell differentiation  (IBA,IDA,IMP)
cell-substrate adhesion  (IMP)
cellular response to hypoxia  (IGI)
cellular response to lipopolysaccharide  (ISO)
decidualization  (ISO)
embryo implantation  (IDA,ISO,TAS)
epidermis development  (TAS)
fatty acid beta-oxidation  (IEP)
fatty acid metabolic process  (IBA)
fatty acid oxidation  (ISO)
fatty acid transport  (IEP)
heart development  (ISO)
hormone-mediated signaling pathway  (IBA)
keratinocyte migration  (IMP)
keratinocyte proliferation  (IMP)
lipid metabolic process  (IMP,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cholesterol storage  (IBA)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of epithelial cell proliferation  (IGI)
negative regulation of inflammatory response  (IBA,ISO)
negative regulation of myoblast differentiation  (IMP)
negative regulation of pri-miRNA transcription by RNA polymerase II  (IDA)
negative regulation of smooth muscle cell migration  (ISO)
negative regulation of smooth muscle cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,IDA)
phospholipid biosynthetic process  (ISO)
placenta development  (IMP)
positive regulation of cell population proliferation  (IMP)
positive regulation of epidermis development  (ISO)
positive regulation of fatty acid metabolic process  (IBA)
positive regulation of fatty acid oxidation  (ISO)
positive regulation of gene expression  (IMP)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of myoblast proliferation  (IMP)
positive regulation of phosphatidylinositol 3-kinase signaling  (IDA)
positive regulation of skeletal muscle tissue regeneration  (IMP)
positive regulation of transcription by RNA polymerase II  (IBA)
positive regulation of transcription, DNA-templated  (ISO)
proteoglycan metabolic process  (ISO)
regulation of cell population proliferation  (IGI,IMP)
regulation of fat cell differentiation  (IMP)
regulation of insulin secretion  (NAS)
regulation of lipid metabolic process  (IBA)
regulation of skeletal muscle satellite cell proliferation  (IMP)
regulation of transcription, DNA-templated  (IEA)
response to activity  (ISO)
response to glucose  (ISO)
response to lipid  (IBA)
response to organic substance  (ISO)
response to vitamin A  (ISO)
vasodilation  (ISO)
vitamin A metabolic process  (ISO)
wound healing  (IMP)

Cellular Component
chromatin  (IDA)
nucleus  (IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal brain morphology  (IAGP)
abnormal circulating protein level  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal compact bone volume  (IAGP)
abnormal energy expenditure  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IEA)
abnormal fat cell morphology  (IAGP)
abnormal gonadal fat pad morphology  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal hair follicle peg morphology  (IAGP)
abnormal keratinocyte adhesion  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal lipid level  (IAGP)
abnormal myelination  (IAGP)
abnormal placenta development  (IAGP)
abnormal response to exercise  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin morphology  (IAGP)
abnormal stratum corneum lipid matrix formation  (IAGP)
colon polyps  (IAGP)
decreased abdominal fat pad weight  (IAGP)
decreased aerobic running capacity  (IAGP)
decreased body size  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone mineral density of femur  (IAGP)
decreased bone stiffness  (IAGP)
decreased bone strength  (IAGP)
decreased bone volume  (IAGP)
decreased brain size  (IAGP)
decreased cholesterol level  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased energy dissipated prior to femur fracture  (IAGP)
decreased fetal size  (IAGP)
decreased interscapular fat pad weight  (IAGP)
decreased keratinocyte proliferation  (IAGP)
decreased lean body mass  (IAGP)
decreased liver cholesterol level  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased mesenteric fat pad weight  (IAGP)
decreased placental labyrinth size  (IAGP)
decreased skeletal muscle mass  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased thermal nociceptive threshold  (IEA)
delayed wound healing  (IAGP)
dilated lateral ventricles  (IEA)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
epidermal hyperplasia  (IAGP)
hypoglycemia  (IAGP)
impaired glucose tolerance  (IAGP)
impaired osteoblast differentiation  (IAGP)
increased bone marrow adipose tissue amount  (IAGP)
increased bone resorption  (IAGP)
increased circulating triglyceride level  (IAGP)
increased circulating VLDL cholesterol level  (IAGP)
increased fatty acids level  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased intestinal adenocarcinoma incidence  (IAGP)
increased intestinal adenoma incidence  (IAGP)
increased keratinocyte apoptosis  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased osteoclast cell number  (IAGP)
increased sebaceous gland adenoma incidence  (IAGP)
increased skin papilloma incidence  (IAGP)
increased skin tumor incidence  (IAGP)
increased total body fat amount  (IAGP)
increased tumor incidence  (IAGP)
intestine polyps  (IAGP)
muscle weakness  (IAGP)
postnatal growth retardation  (IAGP)
prenatal lethality  (IAGP)
prenatal lethality, complete penetrance  (IEA)
prenatal lethality, incomplete penetrance  (IAGP)
reduced fertility  (IAGP)
skin inflammation  (IAGP)
thick epidermis  (IAGP)
thin hypodermis  (IAGP)
thin skin  (IAGP)
underdeveloped hair follicles  (IAGP)
References

Additional References at PubMed
PMID:7588749   PMID:7836471   PMID:8041794   PMID:8240342   PMID:8672143   PMID:8827514   PMID:8889548   PMID:8910358   PMID:9211064   PMID:9918810   PMID:9933587   PMID:10349636  
PMID:10385625   PMID:10393183   PMID:10464095   PMID:10512203   PMID:10713135   PMID:10754535   PMID:10803598   PMID:10866668   PMID:10872826   PMID:11042159   PMID:11076861   PMID:11089532  
PMID:11217851   PMID:11511099   PMID:11514592   PMID:11595815   PMID:11751632   PMID:11756685   PMID:11779158   PMID:11903058   PMID:11923467   PMID:11940593   PMID:12056592   PMID:12059785  
PMID:12118038   PMID:12419217   PMID:12436047   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12540828   PMID:12705865   PMID:12740443   PMID:12763589   PMID:12782154   PMID:12878168  
PMID:12904583   PMID:12943711   PMID:12962497   PMID:12970571   PMID:14502600   PMID:14525942   PMID:14525954   PMID:14610273   PMID:14677574   PMID:14681479   PMID:14684157   PMID:14758356  
PMID:15001550   PMID:15001574   PMID:15033975   PMID:15048110   PMID:15102088   PMID:15210844   PMID:15247146   PMID:15328533   PMID:15380519   PMID:15470497   PMID:15475963   PMID:15480419  
PMID:15489334   PMID:15578089   PMID:15618518   PMID:15632134   PMID:15708854   PMID:15713628   PMID:15730864   PMID:15840001   PMID:15917308   PMID:15944338   PMID:16021179   PMID:16141072  
PMID:16141073   PMID:16166081   PMID:16239641   PMID:16418176   PMID:16467150   PMID:16492734   PMID:16511591   PMID:16581799   PMID:16618765   PMID:16672050   PMID:16698033   PMID:16751185  
PMID:16806672   PMID:16946080   PMID:17084713   PMID:17148604   PMID:17254750   PMID:17275789   PMID:17328923   PMID:17333240   PMID:17380536   PMID:17382197   PMID:17389768   PMID:17418807  
PMID:17437057   PMID:17451173   PMID:17466944   PMID:17637826   PMID:17641685   PMID:17669420   PMID:17671688   PMID:17682064   PMID:17713572   PMID:17962186   PMID:17965409   PMID:17967808  
PMID:17973082   PMID:18007025   PMID:18037994   PMID:18038451   PMID:18096720   PMID:18287559   PMID:18323470   PMID:18330480   PMID:18337495   PMID:18337509   PMID:18354499   PMID:18407349  
PMID:18442472   PMID:18443198   PMID:18445701   PMID:18492772   PMID:18522830   PMID:18522831   PMID:18593727   PMID:18622026   PMID:18622687   PMID:18674809   PMID:18772483   PMID:18799693  
PMID:18799709   PMID:18997443   PMID:19101649   PMID:19197156   PMID:19201410   PMID:19265701   PMID:19294764   PMID:19345188   PMID:19351742   PMID:19389799   PMID:19415321   PMID:19435887  
PMID:19436036   PMID:19513536   PMID:19577614   PMID:19595695   PMID:19633434   PMID:19654299   PMID:19660859   PMID:19675577   PMID:19748995   PMID:19805517   PMID:19838202   PMID:19850007  
PMID:19998413   PMID:20001953   PMID:20009009   PMID:20059953   PMID:20075336   PMID:20209098   PMID:20211142   PMID:20300524   PMID:20378851   PMID:20406305   PMID:20412781   PMID:20427759  
PMID:20445066   PMID:20448152   PMID:20477906   PMID:20624891   PMID:20685850   PMID:20709805   PMID:20729546   PMID:20932939   PMID:21059653   PMID:21070867   PMID:21106494   PMID:21131905  
PMID:21192919   PMID:21205987   PMID:21220704   PMID:21267068   PMID:21300064   PMID:21400612   PMID:21400663   PMID:21426320   PMID:21458563   PMID:21459324   PMID:21511721   PMID:21593381  
PMID:21617181   PMID:21677750   PMID:21725906   PMID:21736821   PMID:21750705   PMID:21798999   PMID:21843327   PMID:21873635   PMID:21884692   PMID:21940900   PMID:22040534   PMID:22072715  
PMID:22090424   PMID:22135324   PMID:22154759   PMID:22179221   PMID:22335598   PMID:22340791   PMID:22538808   PMID:22685301   PMID:22902876   PMID:22916190   PMID:22933110   PMID:22982455  
PMID:22988430   PMID:23077782   PMID:23093780   PMID:23105114   PMID:23176727   PMID:23273766   PMID:23374874   PMID:23500098   PMID:23507144   PMID:23535650   PMID:23542786   PMID:23606724  
PMID:23619236   PMID:23639976   PMID:23811944   PMID:23823620   PMID:23851158   PMID:23861559   PMID:23918045   PMID:23954156   PMID:23977003   PMID:23995233   PMID:24011070   PMID:24069449  
PMID:24086110   PMID:24107399   PMID:24169546   PMID:24203162   PMID:24205877   PMID:24213576   PMID:24268737   PMID:24486511   PMID:24621497   PMID:24639079   PMID:24644281   PMID:24681603  
PMID:24763687   PMID:24864274   PMID:24898257   PMID:24920036   PMID:24952961   PMID:24958459   PMID:25116175   PMID:25149191   PMID:25209981   PMID:25275593   PMID:25279796   PMID:25331977  
PMID:25523142   PMID:25556996   PMID:25662586   PMID:25713055   PMID:25728706   PMID:25753425   PMID:25921579   PMID:25943561   PMID:26028469   PMID:26080426   PMID:26105792   PMID:26242735  
PMID:26253087   PMID:26332891   PMID:26362775   PMID:26642438   PMID:26668503   PMID:26768366   PMID:26935695   PMID:27008868   PMID:27053360   PMID:27150147   PMID:27179975   PMID:27283742  
PMID:27315062   PMID:27345255   PMID:27422605   PMID:27486236   PMID:27597886   PMID:27765815   PMID:27810934   PMID:27856609   PMID:27860527   PMID:27913621   PMID:27935639   PMID:28050012  
PMID:28122051   PMID:28291835   PMID:28404991   PMID:28467934   PMID:28526781   PMID:28555083   PMID:28683290   PMID:28698213   PMID:28751364   PMID:29187400   PMID:29233935   PMID:29289645  
PMID:29346772   PMID:29367760   PMID:29693165   PMID:29882512   PMID:29967008   PMID:30012602   PMID:30213948   PMID:30241392   PMID:30257885   PMID:30580435   PMID:30679176   PMID:30885780  
PMID:30983568   PMID:31062503   PMID:31144304   PMID:31163124   PMID:31321239   PMID:31578267   PMID:31618976   PMID:31688905   PMID:31830829   PMID:31919912   PMID:32066953   PMID:32143325  
PMID:32202512   PMID:32247042   PMID:32315292   PMID:32439961   PMID:32575793   PMID:32651456   PMID:32817369   PMID:32824862   PMID:32892421   PMID:33326461   PMID:34107251  


Genomics

Comparative Map Data
Ppard
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,451,657 - 28,520,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl1728,451,674 - 28,520,448 (+)Ensembl
GRCm381728,232,754 - 28,301,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,232,700 - 28,301,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,369,699 - 28,438,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,960,392 - 28,029,058 (+)NCBImm8
Celera1728,786,405 - 28,855,326 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.64NCBI
PPARD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl635,342,558 - 35,428,191 (+)EnsemblGRCh38hg38GRCh38
GRCh38635,342,558 - 35,428,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37635,310,335 - 35,395,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36635,418,313 - 35,503,933 (+)NCBINCBI36hg18NCBI36
Build 34635,418,363 - 35,501,149NCBI
Celera636,864,336 - 36,949,951 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef635,031,309 - 35,116,788 (+)NCBIHuRef
CHM1_1635,312,398 - 35,397,989 (+)NCBICHM1_1
Ppard
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2206,298,785 - 6,363,970 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl206,298,785 - 6,363,968 (+)Ensembl
Rnor_6.0207,818,289 - 7,883,482 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,818,289 - 7,885,333 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02010,018,464 - 10,083,772 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,479,108 - 6,544,255 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1206,479,323 - 6,543,249 (+)NCBI
Celera207,855,191 - 7,920,274 (+)NCBICelera
RH 3.4 Map2075.52RGD
Cytogenetic Map20p12NCBI
PPARD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,222,589 - 31,295,212 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,222,533 - 31,295,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,141,634 - 36,215,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPARD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11736,695,546 - 36,779,554 (-)NCBI
ChlSab1.1 Ensembl1736,695,494 - 36,779,577 (-)Ensembl
Vero_WHO_p1.0NW_02366604435,262,151 - 35,340,486 (+)NCBI
Ppard
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475422,021,465 - 22,084,320 (-)NCBI

Position Markers
MARC_45800-45801:1102973340:2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,298,404 - 28,298,940UniSTSGRCm38
MGSCv371728,435,349 - 28,435,885UniSTSGRCm37
Celera1728,852,273 - 28,852,809UniSTS
Cytogenetic Map17A3.3UniSTS
Ppard  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371728,434,033 - 28,435,394UniSTSGRCm37
Celera1728,850,957 - 28,852,318UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map1713.5UniSTS
L28116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,299,897 - 28,299,971UniSTSGRCm38
MGSCv371728,436,842 - 28,436,916UniSTSGRCm37
Celera1728,853,766 - 28,853,840UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead_YAC17 UniSTS
PMC117556P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,295,513 - 28,295,872UniSTSGRCm38
MGSCv371728,432,458 - 28,432,817UniSTSGRCm37
Celera1728,849,382 - 28,849,741UniSTS
Cytogenetic Map17A3.3UniSTS
D17Aus7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,293,269 - 28,293,448UniSTSGRCm38
MGSCv371728,430,214 - 28,430,393UniSTSGRCm37
Celera1728,847,138 - 28,847,317UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map1716.4UniSTS
Ppard  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,297,088 - 28,298,449UniSTSGRCm38
MGSCv371728,434,033 - 28,435,394UniSTSGRCm37
Celera1728,850,957 - 28,852,318UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map1713.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17128979566Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17128979566Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17128979566Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17130809908Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17765701129268449Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171661519333600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
12903990Opfaq5_mopen field activity QTL 5 (mouse)172573195128773124Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
12904013Cfq12_mconditioned fear QTL 12 (mouse)172660980730445981Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172765914543574223Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1636
Count of miRNA genes:621
Interacting mature miRNAs:760
Transcripts:ENSMUST00000002320, ENSMUST00000123020, ENSMUST00000142226, ENSMUST00000144200, ENSMUST00000166744, ENSMUST00000169040
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB221579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ417879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ420919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ420920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ420921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ420922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY283201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA978861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF057405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U01665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U10375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_011145   ⟹   NP_035275
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,451,728 - 28,520,443 (+)NCBI
GRCm381728,232,754 - 28,301,469 (+)ENTREZGENE
MGSCv371728,369,699 - 28,438,414 (+)RGD
Celera1728,786,405 - 28,855,326 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036160408   ⟹   XP_036016301
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,499,238 - 28,520,446 (+)NCBI
RefSeq Acc Id: XM_036160409   ⟹   XP_036016302
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,499,243 - 28,520,446 (+)NCBI
RefSeq Acc Id: XM_036160410   ⟹   XP_036016303
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,451,688 - 28,520,446 (+)NCBI
RefSeq Acc Id: XM_036160411   ⟹   XP_036016304
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,451,657 - 28,520,446 (+)NCBI
RefSeq Acc Id: XM_036160412   ⟹   XP_036016305
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,451,688 - 28,520,446 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_035275   ⟸   NM_011145
- UniProtKB: P35396 (UniProtKB/Swiss-Prot),   Q546I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_036016304   ⟸   XM_036160411
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036016303   ⟸   XM_036160410
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036016305   ⟸   XM_036160412
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036016301   ⟸   XM_036160408
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036016302   ⟸   XM_036160409
- Peptide Label: isoform X2
Protein Domains
NR LBD   Nuclear receptor

Promoters
RGD ID:13675332
Promoter ID:EPDNEW_M21815
Type:initiation region
Name:Ppard_1
Description:Mus musculus peroxisome proliferator activator receptor delta, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21816  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381728,232,741 - 28,232,801EPDNEW
RGD ID:13675336
Promoter ID:EPDNEW_M21816
Type:single initiation site
Name:Ppard_2
Description:Mus musculus peroxisome proliferator activator receptor delta, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21815  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381728,255,150 - 28,255,210EPDNEW
RGD ID:6828493
Promoter ID:MM_KWN:22847
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_011145,   OTTMUST00000056747,   UC008BQJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361728,369,529 - 28,370,029 (+)MPROMDB
RGD ID:6847432
Promoter ID:MM_ACW:22233
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:PPARDAND1810013A23RIK.FSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361728,431,631 - 28,432,131 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:101884 AgrOrtholog
Ensembl Genes ENSMUSG00000002250 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000002320 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000133077 UniProtKB/TrEMBL
  ENSMUSP00000156734 UniProtKB/TrEMBL
  ENSMUSP00000156879 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000002320 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000166744 UniProtKB/TrEMBL
  ENSMUST00000169040 UniProtKB/TrEMBL
  ENSMUST00000232879 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 1Cnucl_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1Cnucl_rcpt_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:101884 ENTREZGENE
NCBI Gene 19015 ENTREZGENE
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PPARD RGD
PhenoGen Ppard PhenoGen
PRINTS PROXISOMEPAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROXISOMPABR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2W7W2_MOUSE UniProtKB/TrEMBL
  A0A3B2WD72_MOUSE UniProtKB/TrEMBL
  E9PV57_MOUSE UniProtKB/TrEMBL
  P35396 ENTREZGENE, UniProtKB/Swiss-Prot
  Q546I3 ENTREZGENE, UniProtKB/TrEMBL
  Q7TSY1_MOUSE UniProtKB/TrEMBL
UniProt Secondary P37239 UniProtKB/Swiss-Prot