Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3) - Rat Genome Database

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Gene: Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3) Mus musculus
Analyze
Symbol: Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
RGD ID: 736867
MGI Page MGI
Description: Predicted to have ABC-type transporter activity and anion transmembrane transporter activity. Predicted to be involved in anion transport; drug transmembrane transport; and xenobiotic transport. Localizes to basolateral plasma membrane and integral component of plasma membrane. Is expressed in alimentary system and liver. Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3); PARTICIPATES IN doxorubicin pharmacokinetics pathway; etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; INTERACTS WITH (RS)-coclaurine; (RS)-norcoclaurine; (S)-coclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700019L09Rik; ABC31; ATP-binding cassette protein C3; ATP-binding cassette sub-family C member 3; ATP-binding cassette transporter; canalicular multispecific organic anion transporter 2; MLP2; MOAT-D; MR; MRP3; multidrug resistance-associated protein 3; transporter
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,234,121 - 94,283,843 (-)NCBIGRCm39mm39
GRCm39 Ensembl1194,234,121 - 94,283,823 (-)Ensembl
GRCm381194,343,295 - 94,393,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,343,295 - 94,392,997 (-)EnsemblGRCm38mm10GRCm38
MGSCv371194,204,609 - 94,254,290 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,159,385 - 94,209,066 (-)NCBImm8
Celera11103,962,067 - 104,011,589 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(-)-anisomycin  (ISO)
(RS)-coclaurine  (EXP)
(RS)-norcoclaurine  (EXP)
(S)-coclaurine  (EXP)
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-phenylenediamine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 17-glucosiduronic acid  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetamidofluorene  (ISO)
2-amino-4,6-dinitrotoluene  (ISO)
2-nitrofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5(6)-carboxy-2',7'-dichlorofluorescein  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (ISO)
acetaminophen O-beta-D-glucosiduronic acid  (EXP,ISO)
acrolein  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
alfacalcidol  (EXP)
all-trans-retinoic acid  (EXP,ISO)
allyl alcohol  (EXP)
alpha-hexachlorocyclohexane  (ISO)
alpha-pinene  (ISO)
amikacin  (ISO)
amiodarone  (EXP,ISO)
ampicillin  (ISO)
angelicin  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
atorvastatin calcium  (EXP)
ATP  (EXP)
azathioprine  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
beta-hexachlorocyclohexane  (EXP)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bosentan  (ISO)
bromobenzene  (ISO)
buserelin  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (ISO)
caffeine  (EXP)
calcein am  (ISO)
calcipotriol  (ISO)
calcitriol  (EXP,ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cefalotin  (EXP)
chenodeoxycholic acid  (EXP,ISO)
chloroacetaldehyde  (ISO)
chloroform  (ISO)
chloroprene  (EXP)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
cholate  (ISO)
cholic acid  (EXP,ISO)
choline  (EXP,ISO)
chrysin  (ISO)
ciprofibrate  (EXP)
ciprofloxacin  (EXP)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
clothianidin  (ISO)
clotrimazole  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
coniferyl aldehyde  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
coumarin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (EXP,ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (EXP,ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
Di-n-octyl phthalate  (EXP)
diallyl disulfide  (ISO)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dichloroacetic acid  (EXP)
diethylstilbestrol  (ISO)
Diglycolic acid  (ISO)
dimethylarsinic acid  (ISO)
diosgenin  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
doxycycline  (ISO)
emodin  (EXP,ISO)
endosulfan  (ISO)
enilconazole  (EXP,ISO)
epoxiconazole  (EXP,ISO)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (EXP)
etoposide  (ISO)
felbamate  (ISO)
fenofibrate  (ISO)
Fexofenadine hydrochloride  (EXP)
fipronil  (EXP,ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furosemide  (ISO)
gamma-hexachlorocyclohexane  (ISO)
geneticin  (ISO)
genistein  (EXP,ISO)
ginsenoside Rg1  (EXP)
glutathione  (ISO)
glyburide  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinate  (EXP)
glycyrrhetinic acid  (EXP)
glycyrrhizinic acid  (EXP)
GW 4064  (EXP)
Hexachloro-1,3-butadiene  (ISO)
hexachlorobenzene  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
imipenem hydrate  (EXP)
indole-3-methanol  (ISO)
indometacin  (ISO)
isoniazide  (ISO)
isoprenaline  (EXP,ISO)
L-methionine  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leukotriene C4  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP,ISO)
macitentan  (ISO)
menadione  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methoxsalen  (ISO)
methylarsonic acid  (ISO)
methyltestosterone  (ISO)
metronidazole  (EXP)
metyrapone  (ISO)
mifepristone  (EXP,ISO)
MK 571  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzoylglycine  (ISO)
N-hydroxy-PhIP  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Vinyl-2-pyrrolidone  (ISO)
naloxone  (ISO)
nefazodone  (ISO)
neomycin  (EXP)
nickel sulfate  (ISO)
nifedipine  (ISO)
nimesulide  (ISO)
nocodazole  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
oltipraz  (EXP,ISO)
omeprazole  (ISO)
orphenadrine  (ISO)
ozone  (ISO)
p-menthan-3-ol  (EXP)
p-toluidine  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
parthenolide  (ISO)
PCB138  (ISO)
pentachlorophenol  (EXP)
perfluorodecanoic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perhexiline  (ISO)
phenethyl caffeate  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenytoin  (ISO)
PhIP  (EXP)
physcion  (ISO)
piperonyl butoxide  (EXP,ISO)
Pirarubicin  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
pravastatin  (ISO)
prednisone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
probenecid  (ISO)
prochloraz  (EXP,ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
propane-1,2-diol  (EXP)
propiconazole  (EXP,ISO)
psoralen  (ISO)
pyrazinecarboxamide  (ISO)
pyrrolidines  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
rifampicin  (ISO)
rosuvastatin calcium  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
senecionine  (EXP,ISO)
Senkirkine  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sorafenib  (ISO)
spironolactone  (EXP,ISO)
stilbene oxide  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
sulindac  (ISO)
tamoxifen  (EXP,ISO)
tauro-beta-muricholic acid  (ISO)
taurochenodeoxycholic acid  (ISO)
taurocholic acid  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetraphene  (EXP)
thiacloprid  (EXP,ISO)
thioacetamide  (ISO)
thiophanate-methyl  (EXP)
ticlopidine  (ISO)
titanium dioxide  (EXP)
Tolvaptan  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimethylarsine oxide  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
verapamil  (ISO)
vincristine  (ISO)
yohimbine  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)
ziram  (EXP)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
1. Aleksandrova MI, etal., Bull Exp Biol Med. 2013 Feb;154(4):508-11.
2. Bartholomae S, etal., Pediatr Blood Cancer. 2016 Feb;63(2):242-7. doi: 10.1002/pbc.25785. Epub 2015 Oct 29.
3. Hardwick RN, etal., Drug Metab Dispos. 2012 Mar;40(3):450-60. doi: 10.1124/dmd.111.041095. Epub 2011 Nov 23.
4. Hasegawa Y, etal., J Pharm Pharmacol. 2010 Mar;62(3):310-4. doi: 10.1211/jpp.62.03.0004.
5. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Konig J, etal., Int J Cancer. 2005 Jun 20;115(3):359-67.
7. Kuroda M, etal., J Gastroenterol Hepatol. 2004 Feb;19(2):146-53.
8. Lickteig AJ, etal., Drug Metab Dispos. 2007 Oct;35(10):1970-8. Epub 2007 Jul 19.
9. Lu H and Klaassen C, Drug Metab Dispos. 2008 Jan;36(1):16-23. Epub 2007 Sep 12.
10. McGill MR and Jaeschke H, Pharm Res. 2013 Sep;30(9):2174-87. doi: 10.1007/s11095-013-1007-6. Epub 2013 Mar 6.
11. MGD and Homologene mouse data transfer
12. MGD data from the GO Consortium
13. MGD IEA
14. Naud J, etal., J Pharmacol Exp Ther. 2007 Mar;320(3):978-85. Epub 2006 Nov 29.
15. Nishiya T, etal., Toxicol Sci. 2006 Jun;91(2):651-9. Epub 2006 Mar 16.
16. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
17. Pipeline to import KEGG annotations from KEGG into RGD
18. Pipeline to import SMPDB annotations from SMPDB into RGD
19. RGD automated import pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. Thorn CF, etal., Pharmacogenet Genomics. 2011 Jul;21(7):440-6. doi: 10.1097/FPC.0b013e32833ffb56.
23. Villanueva SS, etal., Drug Metab Dispos. 2008 Mar;36(3):475-80. Epub 2007 Dec 20.
24. Zuniga-Garcia V, etal., Dig Dis Sci. 2015 Aug;60(8):2373-83. doi: 10.1007/s10620-015-3633-9. Epub 2015 Apr 5.
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12837754   PMID:12951053   PMID:14681479   PMID:15802388   PMID:15814571   PMID:15824121   PMID:15886284  
PMID:16141072   PMID:16141073   PMID:16225954   PMID:16250050   PMID:16785251   PMID:16890532   PMID:17204408   PMID:17273943   PMID:17485564   PMID:17845218   PMID:18292224   PMID:18717763  
PMID:19088030   PMID:19443695   PMID:19497955   PMID:19889793   PMID:19996279   PMID:20578149   PMID:21267068   PMID:21677750   PMID:21756856   PMID:21841039   PMID:21873635   PMID:22166395  
PMID:22232210   PMID:23747249   PMID:25952649   PMID:26073088   PMID:26416771   PMID:27480124   PMID:27525577   PMID:29617656  


Genomics

Comparative Map Data
Abcc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,234,121 - 94,283,843 (-)NCBIGRCm39mm39
GRCm39 Ensembl1194,234,121 - 94,283,823 (-)Ensembl
GRCm381194,343,295 - 94,393,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,343,295 - 94,392,997 (-)EnsemblGRCm38mm10GRCm38
MGSCv371194,204,609 - 94,254,290 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,159,385 - 94,209,066 (-)NCBImm8
Celera11103,962,067 - 104,011,589 (-)NCBICelera
Cytogenetic Map11DNCBI
ABCC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1750,634,777 - 50,692,253 (+)EnsemblGRCh38hg38GRCh38
GRCh381750,634,881 - 50,692,253 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371748,712,242 - 48,769,614 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361746,067,227 - 46,124,062 (+)NCBINCBI36hg18NCBI36
Build 341746,067,226 - 46,124,061NCBI
Celera1745,173,593 - 45,230,401 (+)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1744,080,218 - 44,136,477 (+)NCBIHuRef
CHM1_11748,776,209 - 48,833,053 (+)NCBICHM1_1
Abcc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21079,296,681 - 79,342,749 (-)NCBI
Rnor_6.0 Ensembl1082,047,863 - 82,117,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01082,047,308 - 82,116,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01081,896,621 - 81,938,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01081,879,487 - 81,880,151 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41082,986,552 - 83,030,799 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1078,085,499 - 78,131,465 (-)NCBICelera
Cytogenetic Map10q26NCBI
Abcc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,087,570 - 11,130,482 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,087,246 - 11,130,108 (-)NCBIChiLan1.0ChiLan1.0
ABCC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,551,953 - 26,596,330 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,551,268 - 26,595,646 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,944,553 - 25,988,893 (+)NCBI
ROS_Cfam_1.0927,346,054 - 27,390,624 (+)NCBI
UMICH_Zoey_3.1926,113,720 - 26,158,047 (+)NCBI
UNSW_CanFamBas_1.0926,372,406 - 26,416,803 (+)NCBI
UU_Cfam_GSD_1.0926,502,563 - 26,547,109 (+)NCBI
Abcc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,988,457 - 26,035,171 (+)NCBI
SpeTri2.0NW_00493649011,039,968 - 11,086,670 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,920,821 - 26,978,363 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,920,764 - 26,978,389 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,060,930 - 27,117,540 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCC3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11642,646,316 - 42,703,124 (-)NCBI
ChlSab1.1 Ensembl1642,646,812 - 42,702,852 (-)Ensembl
Vero_WHO_p1.0NW_02366607713,362,436 - 13,419,564 (-)NCBI
Abcc3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247956,516,384 - 6,558,332 (+)NCBI

Position Markers
RH136225  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381194,343,439 - 94,343,641UniSTSGRCm38
MGSCv371194,204,753 - 94,204,955UniSTSGRCm37
Celera11103,962,211 - 103,962,413UniSTS
Cytogenetic Map11DUniSTS
D17945  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381194,343,306 - 94,343,458UniSTSGRCm38
MGSCv371194,204,620 - 94,204,772UniSTSGRCm37
Celera11103,962,078 - 103,962,230UniSTS
Cytogenetic Map11DUniSTS
Whitehead_YAC11 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187800372103383289Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118880876299190771Mouse
1301313Pas5a_mpulmonary adenoma susceptibility 5a (mouse)Not determined118907597898974942Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
1300847Par1_mpulmonary adenoma resistance 1 (mouse)Not determined119417295396276595Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir665mmu-miR-665-3pMirecordsexternal_info{changed}NA21559394

Predicted Target Of
Summary Value
Count of predictions:805
Count of miRNA genes:438
Interacting mature miRNAs:501
Transcripts:ENSMUST00000021231, ENSMUST00000126566, ENSMUST00000140985, ENSMUST00000151124, ENSMUST00000155253, ENSMUST00000178136
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001363187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_029600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_879762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF534127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF534128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF534129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY795569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY841885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000021231   ⟹   ENSMUSP00000021231
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,343,298 - 94,392,976 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126566
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,374,623 - 94,392,997 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140985
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,343,655 - 94,351,186 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151124
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,364,855 - 94,392,920 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155253
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,364,210 - 94,367,923 (-)Ensembl
RefSeq Acc Id: ENSMUST00000178136   ⟹   ENSMUSP00000136343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1194,343,295 - 94,392,976 (-)Ensembl
RefSeq Acc Id: NM_001363187   ⟹   NP_001350116
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,234,121 - 94,283,816 (-)NCBI
GRCm381194,343,295 - 94,392,990 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001363189   ⟹   NP_001350118
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,234,121 - 94,283,816 (-)NCBI
GRCm381194,343,295 - 94,392,990 (-)NCBI
Sequence:
RefSeq Acc Id: NM_029600   ⟹   NP_083876
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,234,121 - 94,283,816 (-)NCBI
GRCm381194,343,295 - 94,392,990 (-)NCBI
MGSCv371194,204,609 - 94,254,290 (-)RGD
Celera11103,962,067 - 104,011,589 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_879762
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,236,944 - 94,283,843 (-)NCBI
GRCm381194,343,295 - 94,393,017 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083876   ⟸   NM_029600
- Peptide Label: isoform 2
- UniProtKB: B2RX12 (UniProtKB/Swiss-Prot),   A0A0R4J015 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001350118   ⟸   NM_001363189
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001350116   ⟸   NM_001363187
- Peptide Label: isoform 1
RefSeq Acc Id: ENSMUSP00000136343   ⟸   ENSMUST00000178136
RefSeq Acc Id: ENSMUSP00000021231   ⟸   ENSMUST00000021231
Promoters
RGD ID:6820238
Promoter ID:MM_KWN:9249
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000003820
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361194,213,226 - 94,213,726 (-)MPROMDB
RGD ID:6846944
Promoter ID:MM_ACW:8628
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ABCC3.FSEP07,   YOHANA.ASEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361194,220,341 - 94,220,841 (+)MPROMDB
RGD ID:6820239
Promoter ID:MM_KWN:9251
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Liver
Transcripts:ENSMUST00000107806,   NM_029600,   OTTMUST00000003817,   OTTMUST00000003818,   UC007KYO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361194,253,941 - 94,254,441 (-)MPROMDB
RGD ID:8676202
Promoter ID:EPDNEW_M16131
Type:multiple initiation site
Name:Abcc3_2
Description:Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16132  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381194,371,746 - 94,371,806EPDNEW
RGD ID:8676204
Promoter ID:EPDNEW_M16132
Type:initiation region
Name:Abcc3_1
Description:Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16131  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381194,392,973 - 94,393,033EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923658 AgrOrtholog
Ensembl Genes ENSMUSG00000020865 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000021231 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000136343 ENTREZGENE
Ensembl Transcript ENSMUST00000021231 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000178136 ENTREZGENE
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Multidrug-R_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:76408 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1923658 ENTREZGENE
NCBI Gene 76408 ENTREZGENE
Pfam ABC_membrane UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ABCC3 RGD
PhenoGen Abcc3 PhenoGen
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs MRP_assoc_pro UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J015 ENTREZGENE, UniProtKB/TrEMBL
  B2RX12 ENTREZGENE, UniProtKB/Swiss-Prot
  Q59DK8_MOUSE UniProtKB/TrEMBL
  Q9CVX4_MOUSE UniProtKB/TrEMBL
UniProt Secondary J3QML2 UniProtKB/Swiss-Prot
  Q3U1W8 UniProtKB/Swiss-Prot
  Q56PH0 UniProtKB/Swiss-Prot
  Q59DK9 UniProtKB/Swiss-Prot
  Q59DL0 UniProtKB/Swiss-Prot
  Q5SUF4 UniProtKB/Swiss-Prot
  Q80ZK8 UniProtKB/Swiss-Prot