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Gene: Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3) Mus musculus
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Symbol: Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Description: Predicted to have ATPase activity; ATPase-coupled transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Predicted to be involved in anion transmembrane transport; canalicular bile acid transport; and xenobiotic transport. Localizes to integral component of plasma membrane. Is expressed in alimentary system and liver. Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3); PARTICIPATES IN doxorubicin pharmacokinetics pathway; etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; INTERACTS WITH (RS)-coclaurine; (RS)-norcoclaurine; (S)-coclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700019L09Rik; ABC31; ATP-binding cassette protein C3; ATP-binding cassette sub-family C member 3; ATP-binding cassette transporter; canalicular multispecific organic anion transporter 2; MLP2; MOAT-D; MRP3; multidrug resistance-associated protein 3; transporter
Orthologs:
Homo sapiens (human) : ABCC3 (ATP binding cassette subfamily C member 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abcc3 (ATP binding cassette subfamily C member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc3 (ATP binding cassette subfamily C member 3)
Canis lupus familiaris (dog) : ABCC3 (ATP binding cassette subfamily C member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc3 (ATP binding cassette subfamily C member 3)
Sus scrofa (pig) : ABCC3 (ATP binding cassette subfamily C member 3)
Chlorocebus sabaeus (African green monkey) : ABCC3 (ATP binding cassette subfamily C member 3)
Heterocephalus glaber (naked mole-rat) : Abcc3 (ATP binding cassette subfamily C member 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1194,343,295 - 94,392,997 (-)EnsemblGRCm38mm10GRCm38
GRCm381194,343,295 - 94,393,017 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371194,204,609 - 94,254,290 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,159,385 - 94,209,066 (-)NCBImm8
Celera11103,962,067 - 104,011,589 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abcc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736867
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.