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Gene: Cpt1a (carnitine palmitoyltransferase 1a, liver) Mus musculus
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Symbol: Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
RGD ID: 10390
Description: Exhibits palmitoleoyltransferase activity. Predicted to be involved in several processes, including carnitine metabolic process; positive regulation of fatty acid beta-oxidation; and regulation of insulin secretion. Localizes to mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Used to study carnitine palmitoyltransferase I deficiency. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH (+)-dexrazoxane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C730027G07; carnitine O-palmitoyltransferase 1, liver isoform; carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1, liver; CP; Cpt; CPT I; Cpt1; CPT1-L; CPTI; CPTI-L; L-CPT I
Orthologs:
Homo sapiens (human) : CPT1A (carnitine palmitoyltransferase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cpt1a (carnitine palmitoyltransferase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpt1a (carnitine palmitoyltransferase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CPT1A (carnitine palmitoyltransferase 1A)
Canis lupus familiaris (dog) : CPT1A (carnitine palmitoyltransferase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpt1a (carnitine palmitoyltransferase 1A)
Sus scrofa (pig) : CPT1A (carnitine palmitoyltransferase 1A)
Chlorocebus sabaeus (African green monkey) : CPT1A (carnitine palmitoyltransferase 1A)
Heterocephalus glaber (naked mole-rat) : Cpt1a (carnitine palmitoyltransferase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl193,322,334 - 3,385,733 (+)EnsemblGRCm38mm10GRCm38
GRCm38193,322,326 - 3,385,735 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,323,301 - 3,385,733 (+)NCBIGRCm37mm9NCBIm37
MGSCv36193,334,513 - 3,385,732 (+)NCBImm8
Celera193,192,535 - 3,255,204 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cpt1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10390
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.