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Gene: Cpt1a (carnitine palmitoyltransferase 1a, liver) Mus musculus
Symbol: Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
RGD ID: 10390
Description: Exhibits palmitoleoyltransferase activity. Predicted to be involved in several processes, including carnitine metabolic process; positive regulation of fatty acid beta-oxidation; and regulation of insulin secretion. Localizes to mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Used to study carnitine palmitoyltransferase I deficiency. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH (+)-dexrazoxane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C730027G07; carnitine O-palmitoyltransferase 1, liver isoform; carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1, liver; CP; Cpt; CPT I; Cpt1; CPT1-L; CPTI; CPTI-L; L-CPT I
Homo sapiens (human) : CPT1A (carnitine palmitoyltransferase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cpt1a (carnitine palmitoyltransferase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpt1a (carnitine palmitoyltransferase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CPT1A (carnitine palmitoyltransferase 1A)
Canis lupus familiaris (dog) : CPT1A (carnitine palmitoyltransferase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpt1a (carnitine palmitoyltransferase 1A)
Sus scrofa (pig) : CPT1A (carnitine palmitoyltransferase 1A)
Chlorocebus sabaeus (African green monkey) : CPT1A (carnitine palmitoyltransferase 1A)
Heterocephalus glaber (naked mole-rat) : Cpt1a (carnitine palmitoyltransferase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl193,322,334 - 3,385,733 (+)EnsemblGRCm38mm10GRCm38
GRCm38193,322,326 - 3,385,735 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,323,301 - 3,385,733 (+)NCBIGRCm37mm9NCBIm37
MGSCv36193,334,513 - 3,385,732 (+)NCBImm8
Celera193,192,535 - 3,255,204 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cpt1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10390
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.