Pvr (poliovirus receptor) - Rat Genome Database
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Gene: Pvr (poliovirus receptor) Mus musculus
Analyze
Symbol: Pvr
Name: poliovirus receptor
RGD ID: 736514
MGI Page MGI
Description: Exhibits dynein light chain binding activity. Involved in cell migration and cell-cell adhesion. Localizes to cell surface and plasma membrane. Orthologous to human PVR (PVR cell adhesion molecule); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3830421F03Rik; CD155; D7Ertd458; D7Ertd458e; HVED; mE4; necl; necl-5; PVS; Ta; Taa1; Tage; Tage4; tumor-associated antigen 1
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,637,503 - 19,655,068 (-)NCBIGRCm39mm39
GRCm38719,903,578 - 19,921,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,903,578 - 19,921,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,488,927 - 20,506,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv36719,062,100 - 19,079,613 (-)NCBImm8
Celera717,310,717 - 17,327,912 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bromobenzene  (ISO)
cadmium dichloride  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chloroform  (ISO)
cisplatin  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
D-glucose  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
fluoranthene  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
glucose  (EXP)
glycidol  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphite  (ISO)
indole-3-methanol  (ISO)
isoprenaline  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (EXP)
ranitidine  (ISO)
rotenone  (ISO)
silicon dioxide  (EXP)
Soman  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
torcetrapib  (ISO)
trichloroethene  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)

References

Additional References at PubMed
PMID:8678999   PMID:8980189   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11751937   PMID:12466851   PMID:12477932   PMID:12520002  
PMID:12740392   PMID:12759359   PMID:14652024   PMID:14871893   PMID:15213219   PMID:15688018   PMID:15752754   PMID:16141072   PMID:16141073   PMID:16249389   PMID:17145500   PMID:17156749  
PMID:17286202   PMID:17314315   PMID:17352739   PMID:17446174   PMID:17621371   PMID:17637752   PMID:17893876   PMID:17971293   PMID:18298801   PMID:18973187   PMID:19056733   PMID:19380711  
PMID:19688744   PMID:20008292   PMID:20048123   PMID:20964795   PMID:21267068   PMID:21416464   PMID:21677750   PMID:21873635   PMID:22027834   PMID:22072781   PMID:22209676   PMID:22282193  
PMID:22429743   PMID:23349877   PMID:23539219   PMID:24034254   PMID:24658051   PMID:24817116   PMID:24948196   PMID:25384044   PMID:25818301   PMID:25972481   PMID:26588911   PMID:26689152  
PMID:26840537   PMID:27733379   PMID:29757192   PMID:30315271   PMID:30591568   PMID:31022697   PMID:32274496  


Genomics

Comparative Map Data
Pvr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,637,503 - 19,655,068 (-)NCBIGRCm39mm39
GRCm38719,903,578 - 19,921,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,903,578 - 19,921,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,488,927 - 20,506,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv36719,062,100 - 19,079,613 (-)NCBImm8
Celera717,310,717 - 17,327,912 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
PVR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1944,643,798 - 44,666,162 (+)EnsemblGRCh38hg38GRCh38
GRCh381944,643,910 - 44,666,162 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371945,147,098 - 45,169,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,839,066 - 49,858,690 (+)NCBINCBI36hg18NCBI36
Build 341949,839,065 - 49,858,689NCBI
Celera1941,951,144 - 41,973,471 (+)NCBI
Cytogenetic Map19q13.31NCBI
HuRef1941,579,341 - 41,601,754 (+)NCBIHuRef
CHM1_11945,149,748 - 45,172,111 (+)NCBICHM1_1
Pvr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0180,820,306 - 80,835,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,820,050 - 80,835,701 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,085,555 - 82,100,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,213,654 - 79,229,063 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1179,291,499 - 79,307,163 (-)NCBI
Celera174,018,461 - 74,033,867 (-)NCBICelera
Cytogenetic Map1q21NCBI
RH 3.4 Map1819.8RGD
PVR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11950,196,980 - 50,216,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,196,980 - 50,217,006 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01941,592,042 - 41,614,397 (+)NCBIMhudiblu_PPA_v0panPan3
PVR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1110,697,911 - 110,754,296 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11110,692,906 - 110,713,209 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
PVR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1651,161,320 - 51,178,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,020,048 - 47,038,024 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234825
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,127,864 - 38,141,612 (+)NCBI

Position Markers
D7Ertd458e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38719,903,595 - 19,903,843UniSTSGRCm38
MGSCv37720,488,944 - 20,489,192UniSTSGRCm37
Celera717,310,734 - 17,310,982UniSTS
Cytogenetic Map7A3UniSTS
cM Map74.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301377Mprf_mmaternal performance (mouse)Not determined7120266693Mouse
10043984Pbft4_mpercent body fat 4 (mouse)Not determined7120266693Mouse
1301177Vent3_mventricular size 3 (mouse)Not determined7120463409Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120463409Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121695147Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121818048Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121818048Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121818048Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7269777136697919Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7330353225179993Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7346321287493512Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360000072900000Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined71028944244289559Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71060637344606511Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71278145246781452Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71278145246781452Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1333306047333196Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71343577947435779Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71360000047700000Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71690336849509583Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71899486940024609Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71958059053580679Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:984
Count of miRNA genes:550
Interacting mature miRNAs:664
Transcripts:ENSMUST00000043517, ENSMUST00000159261, ENSMUST00000159413, ENSMUST00000160572
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_027514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB195430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ563420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY276828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS458409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000043517   ⟹   ENSMUSP00000039205
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl719,903,578 - 19,921,160 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159261
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl719,917,277 - 19,921,113 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl719,905,071 - 19,910,864 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160572
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl719,915,764 - 19,921,113 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208861
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl719,914,024 - 19,914,762 (-)Ensembl
RefSeq Acc Id: NM_027514   ⟹   NP_081790
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,637,503 - 19,655,068 (-)NCBI
GRCm38719,903,578 - 19,921,143 (-)ENTREZGENE
MGSCv37720,488,927 - 20,506,492 (-)RGD
Celera717,310,717 - 17,327,912 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081790   ⟸   NM_027514
- Peptide Label: precursor
- UniProtKB: Q8K094 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000039205   ⟸   ENSMUST00000043517
Protein Domains
Ig-like

Promoters
RGD ID:6892138
Promoter ID:EPDNEW_M9520
Type:initiation region
Name:Pvr_1
Description:Mus musculus poliovirus receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38719,921,113 - 19,921,173EPDNEW
RGD ID:6841892
Promoter ID:MM_KWN:49112
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   MEF_B6
Transcripts:OTTMUST00000081421
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36720,495,991 - 20,496,842 (-)MPROMDB
RGD ID:6841888
Promoter ID:MM_KWN:49115
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000078105,   OTTMUST00000078106,   OTTMUST00000078107
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36720,506,361 - 20,507,232 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107741 AgrOrtholog
Ensembl Genes ENSMUSG00000040511 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000039205 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000043517 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report mmu:52118 UniProtKB/TrEMBL
MGD MGI:107741 ENTREZGENE
NCBI Gene 52118 ENTREZGENE
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Pvr PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniGene Mm.227506 ENTREZGENE
UniProt Q60977_MOUSE UniProtKB/TrEMBL
  Q8BVF6_MOUSE UniProtKB/TrEMBL
  Q8K094 ENTREZGENE, UniProtKB/TrEMBL
  Q91WP1_MOUSE UniProtKB/TrEMBL