Dnmt3a (DNA methyltransferase 3A) - Rat Genome Database

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Gene: Dnmt3a (DNA methyltransferase 3A) Mus musculus
Analyze
Symbol: Dnmt3a
Name: DNA methyltransferase 3A
RGD ID: 1620920
MGI Page MGI
Description: Enables DNA binding activity; S-adenosylmethionine-dependent methyltransferase activity; and chromatin binding activity. Involved in DNA methylation involved in gamete generation; hypermethylation of CpG island; and regulation of gene expression by genetic imprinting. Acts upstream of or within several processes, including DNA methylation involved in embryo development; cellular response to amino acid stimulus; and negative regulation of transcription, DNA-templated. Located in chromosome; cytoplasm; and nucleus. Is expressed in several structures, including brain; early conceptus; reproductive system; sensory organ; and urethra. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndrome; and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AU015806; cysteine methyltransferase DNMT3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase MmuIIIA; DNA MTase MmuIIIA; m.MmuIIIA; MmuIIIA; W91664
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Dnmt3a-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,851,559 - 3,964,443 (+)NCBIGRCm39mm39
GRCm39 Ensembl123,856,007 - 3,964,443 (+)Ensembl
GRCm38123,801,559 - 3,914,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,806,007 - 3,914,443 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,806,980 - 3,914,443 (+)NCBIGRCm37mm9NCBIm37
MGSCv36123,835,027 - 3,914,455 (+)NCBImm8
Celera123,763,156 - 3,842,112 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5-(hydroxymethyl)cytosine  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
amphetamine  (ISO)
androgen antagonist  (ISO)
aripiprazole  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
buta-1,3-diene  (EXP)
Butylparaben  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
citalopram  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-penicillamine  (EXP)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
DDE  (ISO)
DDT  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
Difenacoum  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzacamene  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
Flocoumafen  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fulvestrant  (EXP)
fumonisin B1  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gibberellin A3  (ISO)
glycitein  (ISO)
glycitin  (ISO)
glyphosate  (ISO)
guggulsterone  (ISO)
hexane  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
isoprenaline  (EXP,ISO)
L-methionine  (EXP,ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
microcystin-LR  (ISO)
mitomycin C  (EXP)
Monobutylphthalate  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-methylformamide  (EXP)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
procyanidin B2  (ISO)
pterostilbene  (ISO)
quartz  (ISO)
quinoline  (EXP)
resveratrol  (ISO)
S-adenosyl-L-methioninate  (EXP,ISO)
S-adenosyl-L-methionine  (EXP,ISO)
Salinomycin  (ISO)
sinefungin  (EXP)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (EXP)
troglitazone  (EXP)
tungsten  (EXP)
tyrphostin AG 1478  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vinyl carbamate  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
withaferin A  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Cavuoto P and Fenech MF, Cancer Treat Rev. 2012 Oct;38(6):726-36. doi: 10.1016/j.ctrv.2012.01.004. Epub 2012 Feb 17.
2. Cowin PA, etal., Endocrinology. 2010 Feb;151(2):783-92. doi: 10.1210/en.2009-0982. Epub 2010 Jan 7.
3. Dawson MA and Kouzarides T, Cell. 2012 Jul 6;150(1):12-27. doi: 10.1016/j.cell.2012.06.013.
4. Delatte B, etal., EMBO J. 2014 Jun 2;33(11):1198-211. doi: 10.15252/embj.201488290. Epub 2014 May 13.
5. El Ghannam D, etal., Blood Cells Mol Dis. 2014 Jun-Aug;53(1-2):61-6. doi: 10.1016/j.bcmd.2014.01.004. Epub 2014 Feb 8.
6. Fan H, etal., BMC Med. 2010 Feb 3;8:12. doi: 10.1186/1741-7015-8-12.
7. Feng Y, etal., J Nutr Biochem. 2013 Jul;24(7):1373-80. doi: 10.1016/j.jnutbio.2012.11.005. Epub 2013 Jan 17.
8. Feng YJ, etal., Zhonghua Yi Xue Za Zhi. 2013 Dec 24;93(48):3822-5.
9. Grossmann V, etal., Genes Chromosomes Cancer. 2013 Apr;52(4):410-22. doi: 10.1002/gcc.22039. Epub 2013 Jan 23.
10. Imai S, etal., J Neurosci. 2011 Oct 26;31(43):15294-9. doi: 10.1523/JNEUROSCI.0921-11.2011.
11. Jiang JX, etal., PLoS One. 2013 Aug 7;8(8):e69089. doi: 10.1371/journal.pone.0069089. eCollection 2013.
12. LaPlant Q, etal., Nat Neurosci. 2010 Sep;13(9):1137-43. doi: 10.1038/nn.2619. Epub 2010 Aug 22.
13. Li W, etal., Leuk Lymphoma. 2015 Apr;56(4):1066-71. doi: 10.3109/10428194.2014.947607. Epub 2014 Nov 10.
14. Lin J, etal., PLoS One. 2011;6(10):e26906. doi: 10.1371/journal.pone.0026906. Epub 2011 Oct 31.
15. Liu WB, etal., Toxicol Appl Pharmacol. 2011 Feb 15;251(1):70-8. doi: 10.1016/j.taap.2010.12.002. Epub 2010 Dec 14.
16. Liu X and Guo SW, Gynecol Obstet Invest. 2012;74(2):100-8. Epub 2012 May 4.
17. Liu YN, etal., J Huazhong Univ Sci Technolog Med Sci. 2015 Jun;35(3):337-42. doi: 10.1007/s11596-015-1434-1. Epub 2015 Jun 14.
18. Majumder S, etal., J Biol Chem. 2002 May 3;277(18):16048-58. Epub 2002 Feb 13.
19. Marcucci G, etal., J Clin Oncol. 2012 Mar 1;30(7):742-50. doi: 10.1200/JCO.2011.39.2092. Epub 2012 Jan 30.
20. Mayle A, etal., Blood. 2015 Jan 22;125(4):629-38.
21. Mizuno S, etal., Blood. 2001 Mar 1;97(5):1172-9.
22. Morey SR, etal., Cancer Res. 2006 Dec 15;66(24):11659-67.
23. Pandi G, etal., PLoS One. 2013;8(3):e58039. doi: 10.1371/journal.pone.0058039. Epub 2013 Mar 13.
24. Park HJ, etal., Cancer Lett. 2006 Feb 28;233(2):271-8.
25. Pipeline to import KEGG annotations from KEGG into RGD
26. RGD automated import pipeline
27. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
28. RGD automated import pipeline for gene-chemical interactions
29. Sehgal AR, etal., Clin Cancer Res. 2015 Apr 1;21(7):1614-20. doi: 10.1158/1078-0432.CCR-14-0327. Epub 2015 Jan 21.
30. Tao J, etal., J Clin Immunol. 2008 Sep;28(5):432-9. doi: 10.1007/s10875-008-9223-2. Epub 2008 Aug 6.
31. Walter MJ, etal., Leukemia. 2011 Jul;25(7):1153-8. doi: 10.1038/leu.2011.44. Epub 2011 Mar 18.
32. Wong M, etal., Front Cell Neurosci. 2013 Dec 25;7:279. doi: 10.3389/fncel.2013.00279. eCollection 2013.
33. Wu X, etal., Neurosci Bull. 2013 Dec;29(6):685-92. doi: 10.1007/s12264-013-1345-8. Epub 2013 May 28.
34. Wu Y, etal., Fertil Steril. 2007 Jan;87(1):24-32. Epub 2006 Nov 1.
35. Zhang YY, etal., Leuk Res. 2015 Oct;39(10):1041-7. doi: 10.1016/j.leukres.2015.06.015. Epub 2015 Jul 6.
Additional References at PubMed
PMID:8772199   PMID:8889548   PMID:9662389   PMID:10349636   PMID:10555141   PMID:10575238   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11350943  
PMID:11399089   PMID:11821381   PMID:11919202   PMID:11934864   PMID:12138111   PMID:12351185   PMID:12370304   PMID:12406579   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12616525  
PMID:12787669   PMID:12869530   PMID:12897133   PMID:12904583   PMID:14610273   PMID:14681479   PMID:14752048   PMID:14760703   PMID:14998934   PMID:14998998   PMID:15063176   PMID:15215868  
PMID:15310660   PMID:15317747   PMID:15456861   PMID:15456878   PMID:15489334   PMID:15522198   PMID:15533817   PMID:15567719   PMID:15616584   PMID:15634679   PMID:15671018   PMID:15672446  
PMID:15735669   PMID:15739230   PMID:15757890   PMID:15919778   PMID:16026162   PMID:16141072   PMID:16141073   PMID:16283622   PMID:16288735   PMID:16322236   PMID:16362968   PMID:16395332  
PMID:16439359   PMID:16472822   PMID:16501171   PMID:16565708   PMID:16584789   PMID:16602821   PMID:16631596   PMID:16682412   PMID:16725135   PMID:16824199   PMID:16840553   PMID:16973295  
PMID:16999741   PMID:17048991   PMID:17175537   PMID:17182866   PMID:17420264   PMID:17439403   PMID:17445268   PMID:17477386   PMID:17485486   PMID:17579209   PMID:17616512   PMID:17687327  
PMID:17713477   PMID:17938196   PMID:17982445   PMID:17989773   PMID:17994007   PMID:18157120   PMID:18191145   PMID:18241125   PMID:18365873   PMID:18381894   PMID:18452947   PMID:18536344  
PMID:18536530   PMID:18541703   PMID:18544626   PMID:18559477   PMID:18667590   PMID:18757295   PMID:18784354   PMID:18799693   PMID:18823905   PMID:18932249   PMID:18945701   PMID:18953337  
PMID:19161295   PMID:19228594   PMID:19386473   PMID:19509302   PMID:19625655   PMID:19632198   PMID:19680236   PMID:19727073   PMID:19798101   PMID:19921333   PMID:20011505   PMID:20059948  
PMID:20059953   PMID:20132320   PMID:20211142   PMID:20228804   PMID:20348135   PMID:20362542   PMID:20367604   PMID:20385583   PMID:20489138   PMID:20507910   PMID:20547484   PMID:20548288  
PMID:20573497   PMID:20577743   PMID:20651149   PMID:20889571   PMID:20966256   PMID:21047779   PMID:21057502   PMID:21057543   PMID:21092094   PMID:21118511   PMID:21172419   PMID:21174446  
PMID:21194568   PMID:21233130   PMID:21262766   PMID:21267068   PMID:21452232   PMID:21454628   PMID:21481189   PMID:21566127   PMID:21576263   PMID:21589869   PMID:21624812   PMID:21677750  
PMID:21695170   PMID:21706000   PMID:21731673   PMID:21905163   PMID:22011581   PMID:22056672   PMID:22086334   PMID:22090490   PMID:22134929   PMID:22138693   PMID:22190484   PMID:22269950  
PMID:22315408   PMID:22387999   PMID:22516971   PMID:22580371   PMID:22584578   PMID:22714992   PMID:22751036   PMID:22761581   PMID:22837034   PMID:22898819   PMID:22913541   PMID:23284304  
PMID:23293288   PMID:23393137   PMID:23399934   PMID:23444399   PMID:23611774   PMID:23641003   PMID:23665319   PMID:23772023   PMID:23825703   PMID:23866265   PMID:23920106   PMID:24074865  
PMID:24124161   PMID:24127215   PMID:24167195   PMID:24183668   PMID:24194600   PMID:24270360   PMID:24292811   PMID:24357321   PMID:24362762   PMID:24457600   PMID:24497509   PMID:24530979  
PMID:24599402   PMID:24645644   PMID:24698270   PMID:24837369   PMID:24895120   PMID:24937014   PMID:24941955   PMID:24952961   PMID:25123312   PMID:25130491   PMID:25147181   PMID:25335909  
PMID:25349213   PMID:25389311   PMID:25392496   PMID:25416276   PMID:25445743   PMID:25476147   PMID:25476906   PMID:25487288   PMID:25569111   PMID:25634742   PMID:25639876   PMID:25706873  
PMID:25713087   PMID:25762136   PMID:25766529   PMID:25772072   PMID:25801914   PMID:25821913   PMID:25822089   PMID:26003733   PMID:26023099   PMID:26030024   PMID:26059604   PMID:26098432  
PMID:26417043   PMID:26482727   PMID:26576615   PMID:26595813   PMID:26631740   PMID:26674863   PMID:26710888   PMID:26751286   PMID:26791204   PMID:26808831   PMID:26812015   PMID:26843651  
PMID:26876596   PMID:26952936   PMID:27010239   PMID:27016502   PMID:27122033   PMID:27134162   PMID:27149841   PMID:27240213   PMID:27300438   PMID:27306334   PMID:27335278   PMID:27344947  
PMID:27387481   PMID:27415617   PMID:27428748   PMID:27516062   PMID:27545441   PMID:27582468   PMID:27626380   PMID:27636998   PMID:27677595   PMID:27681438   PMID:27690235   PMID:27824296  
PMID:27826835   PMID:27841873   PMID:27841881   PMID:27865785   PMID:27906176   PMID:27939986   PMID:27956497   PMID:28114345   PMID:28167789   PMID:28267064   PMID:28270689   PMID:28317850  
PMID:28321121   PMID:28425913   PMID:28451635   PMID:28461508   PMID:28614801   PMID:28648661   PMID:28712054   PMID:28849714   PMID:28872462   PMID:28976982   PMID:29027601   PMID:29056337  
PMID:29074627   PMID:29091029   PMID:29146735   PMID:29162810   PMID:29164502   PMID:29236683   PMID:29254152   PMID:29326230   PMID:29572461   PMID:29617651   PMID:29728415   PMID:29748607  
PMID:29750576   PMID:29765016   PMID:29850805   PMID:30001199   PMID:30058429   PMID:30102379   PMID:30186101   PMID:30321403   PMID:30366920   PMID:30385711   PMID:30487604   PMID:30518531  
PMID:30530687   PMID:30638145   PMID:30644360   PMID:30684388   PMID:30692594   PMID:30759395   PMID:30834655   PMID:30850438   PMID:30975723   PMID:31015495   PMID:31027045   PMID:31124216  
PMID:31361780   PMID:31435645   PMID:31467060   PMID:31530896   PMID:31558711   PMID:31634469   PMID:31703632   PMID:31784358   PMID:31784360   PMID:31792207   PMID:31823782   PMID:32027825  
PMID:32052888   PMID:32061563   PMID:32123907   PMID:32159514   PMID:32173286   PMID:32220332   PMID:32222282   PMID:32325033   PMID:32353257   PMID:32445940   PMID:32514790   PMID:32561758  
PMID:32581223   PMID:32589877   PMID:32674113   PMID:32756009   PMID:32892421   PMID:33110091   PMID:33159179   PMID:33238114   PMID:33513138   PMID:33850140   PMID:33986537   PMID:34315901  


Genomics

Comparative Map Data
Dnmt3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,851,559 - 3,964,443 (+)NCBIGRCm39mm39
GRCm39 Ensembl123,856,007 - 3,964,443 (+)Ensembl
GRCm38123,801,559 - 3,914,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,806,007 - 3,914,443 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,806,980 - 3,914,443 (+)NCBIGRCm37mm9NCBIm37
MGSCv36123,835,027 - 3,914,455 (+)NCBImm8
Celera123,763,156 - 3,842,112 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
DNMT3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl225,227,855 - 25,342,590 (-)EnsemblGRCh38hg38GRCh38
GRCh38225,227,874 - 25,342,590 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37225,450,743 - 25,565,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36225,309,349 - 25,418,963 (-)NCBINCBI36hg18NCBI36
Celera225,296,144 - 25,405,816 (-)NCBI
Cytogenetic Map2p23.3NCBI
HuRef225,193,733 - 25,302,862 (-)NCBIHuRef
CHM1_1225,385,740 - 25,495,369 (-)NCBICHM1_1
Dnmt3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2626,791,517 - 26,902,161 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl626,822,609 - 26,896,687 (+)Ensembl
Rnor_6.0628,205,375 - 28,346,052 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl628,235,695 - 28,340,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0638,044,960 - 38,082,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0638,132,683 - 38,149,613 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,802,612 - 26,878,878 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,805,564 - 26,881,831 (+)NCBI
Celera626,297,300 - 26,371,904 (+)NCBICelera
Cytogenetic Map6q14NCBI
Dnmt3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,269,952 - 7,367,059 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,264,431 - 7,367,059 (-)NCBIChiLan1.0ChiLan1.0
DNMT3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A25,331,095 - 25,441,785 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A25,331,095 - 25,412,605 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A25,229,593 - 25,344,733 (-)NCBIMhudiblu_PPA_v0panPan3
DNMT3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11719,489,524 - 19,563,074 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1719,492,193 - 19,563,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1719,382,990 - 19,486,679 (-)NCBI
ROS_Cfam_1.01719,761,597 - 19,865,311 (-)NCBI
UMICH_Zoey_3.11719,495,608 - 19,599,241 (-)NCBI
UNSW_CanFamBas_1.01719,505,342 - 19,609,205 (-)NCBI
UU_Cfam_GSD_1.01719,551,811 - 19,655,519 (-)NCBI
Dnmt3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629263,826,309 - 63,930,744 (-)NCBI
SpeTri2.0NW_0049364936,963,406 - 7,013,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNMT3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3113,528,926 - 113,609,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13113,501,972 - 113,609,148 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23120,579,692 - 120,663,698 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNMT3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11482,313,414 - 82,427,170 (+)NCBI
ChlSab1.11482,313,414 - 82,427,170 (+)NCBI
ChlSab1.1 Ensembl1482,402,826 - 82,420,819 (+)Ensembl
Vero_WHO_p1.0NW_02366604529,732,050 - 29,846,532 (-)NCBI
Dnmt3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247387,481,084 - 7,581,332 (-)NCBI

Position Markers
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,899,943 - 3,900,012UniSTSGRCm38
MGSCv37123,899,943 - 3,900,012UniSTSGRCm37
Celera123,827,803 - 3,827,872UniSTS
Cytogenetic Map12A2-A3UniSTS
cM Map12 UniSTS
AU015806  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,908,667 - 3,908,795UniSTSGRCm38
MGSCv37123,908,667 - 3,908,795UniSTSGRCm37
Celera123,836,336 - 3,836,464UniSTS
Cytogenetic Map12A2-A3UniSTS
Whitehead/MRC_RH1225.08UniSTS
RH125299  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,908,793 - 3,908,913UniSTSGRCm38
MGSCv37123,908,793 - 3,908,913UniSTSGRCm37
Celera123,836,462 - 3,836,582UniSTS
Cytogenetic Map12A2-A3UniSTS
UniSTS:236800  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,912,482 - 3,912,681UniSTSGRCm38
MGSCv37123,912,482 - 3,912,681UniSTSGRCm37
Celera123,840,151 - 3,840,350UniSTS
Cytogenetic Map12A2-A3UniSTS
RH139204  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,908,152 - 3,908,365UniSTSGRCm38
MGSCv37123,908,152 - 3,908,365UniSTSGRCm37
Celera123,835,821 - 3,836,034UniSTS
Cytogenetic Map12A2-A3UniSTS
MARC_26721-26722:1034781098:3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,901,651 - 3,902,438UniSTSGRCm38
MGSCv37123,901,651 - 3,902,438UniSTSGRCm37
Celera123,829,320 - 3,830,107UniSTS
Cytogenetic Map12A2-A3UniSTS
RH130466  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,906,818 - 3,907,755UniSTSGRCm38
MGSCv37123,906,818 - 3,907,755UniSTSGRCm37
Celera123,834,487 - 3,835,424UniSTS
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,899,218 - 3,899,696UniSTSGRCm38
MGSCv37123,899,218 - 3,899,696UniSTSGRCm37
Celera123,827,078 - 3,827,556UniSTS
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS
cM Map12 UniSTS
AU015806  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,908,676 - 3,908,882UniSTSGRCm38
MGSCv37123,908,676 - 3,908,882UniSTSGRCm37
Celera123,836,345 - 3,836,551UniSTS
Cytogenetic Map12A2-A3UniSTS
Whitehead/MRC_RH1223.73UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS
Dnmt3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A2-A3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122368579Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122368579Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122368579Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122368579Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124612697Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124612697Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127870733Mouse
4141112Tglq2a_mtriglyceride QTL 2a (mouse)Not determined12127870733Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127870733Mouse
9850128Tglq5_mtriglyceride QTL 5 (mouse)Not determined12127870733Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130383077Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132708755Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133380338Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1229013334290301Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12360000029700000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir29b-1mmu-miR-29b-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI19959559
Mir29b-1mmu-miR-29b-3pMirtarbaseexternal_infoLuciferase reporter assay//mRAP//Northern blotFunctional MTI19509302
Mir29b-1mmu-miR-29b-3pOncomiRDBexternal_infoNANA23100393
Mir29b-1mmu-miR-29b-3pOncomiRDBexternal_infoNANA19211935
Mir29b-1mmu-miR-29b-3pOncomiRDBexternal_infoNANA17890317
Mir143mmu-miR-143-3pOncomiRDBexternal_infoNANA19638978
Mir29cmmu-miR-29c-3pOncomiRDBexternal_infoNANA17890317
Mir29ammu-miR-29a-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI19959559
Mir29ammu-miR-29a-3pOncomiRDBexternal_infoNANA17890317
Mir29b-2mmu-miR-29b-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI19959559
Mir29b-2mmu-miR-29b-3pMirtarbaseexternal_infoLuciferase reporter assay//mRAP//Northern blotFunctional MTI19509302
Mir29b-2mmu-miR-29b-3pOncomiRDBexternal_infoNANA23100393
Mir29b-2mmu-miR-29b-3pOncomiRDBexternal_infoNANA19211935
Mir29b-2mmu-miR-29b-3pOncomiRDBexternal_infoNANA17890317

Predicted Target Of
Summary Value
Count of predictions:8555
Count of miRNA genes:1029
Interacting mature miRNAs:1579
Transcripts:ENSMUST00000020991, ENSMUST00000085826, ENSMUST00000111186, ENSMUST00000172509, ENSMUST00000172689, ENSMUST00000172719, ENSMUST00000172749, ENSMUST00000172816, ENSMUST00000172879, ENSMUST00000172913, ENSMUST00000173197, ENSMUST00000173700, ENSMUST00000174102, ENSMUST00000174272, ENSMUST00000174483, ENSMUST00000174733, ENSMUST00000174774, ENSMUST00000174817
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC159324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF068625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF480164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF503865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF503866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF503867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE855330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM963211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ042850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB058054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB590809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF580263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ104461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN526792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020991   ⟹   ENSMUSP00000020991
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,857,030 - 3,964,443 (+)Ensembl
GRCm38.p6 Ensembl123,807,030 - 3,914,443 (+)Ensembl
RefSeq Acc Id: ENSMUST00000085826
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,856,498 - 3,917,484 (+)Ensembl
GRCm38.p6 Ensembl123,806,498 - 3,867,484 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111186   ⟹   ENSMUSP00000106817
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,941,744 - 3,964,443 (+)Ensembl
GRCm38.p6 Ensembl123,891,744 - 3,914,443 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172509   ⟹   ENSMUSP00000133869
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,857,058 - 3,946,995 (+)Ensembl
GRCm38.p6 Ensembl123,807,058 - 3,896,995 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172689   ⟹   ENSMUSP00000133543
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,941,728 - 3,957,842 (+)Ensembl
GRCm38.p6 Ensembl123,891,728 - 3,907,842 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172719   ⟹   ENSMUSP00000133501
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,856,527 - 3,923,381 (+)Ensembl
GRCm38.p6 Ensembl123,806,527 - 3,873,381 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172749   ⟹   ENSMUSP00000134567
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,945,593 - 3,947,365 (+)Ensembl
GRCm38.p6 Ensembl123,895,593 - 3,897,365 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172816   ⟹   ENSMUSP00000134632
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,911,021 - 3,916,162 (+)Ensembl
GRCm38.p6 Ensembl123,861,021 - 3,866,162 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172879   ⟹   ENSMUSP00000134689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,944,824 - 3,945,676 (+)Ensembl
GRCm38.p6 Ensembl123,894,824 - 3,895,676 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172913   ⟹   ENSMUSP00000134496
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,956,816 - 3,958,547 (+)Ensembl
GRCm38.p6 Ensembl123,906,816 - 3,908,547 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173197   ⟹   ENSMUSP00000133567
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,916,191 - 3,926,062 (+)Ensembl
GRCm38.p6 Ensembl123,866,191 - 3,876,062 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173700
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,856,007 - 3,888,814 (+)Ensembl
GRCm38.p6 Ensembl123,806,007 - 3,838,814 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174102   ⟹   ENSMUSP00000134480
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,935,449 - 3,946,121 (+)Ensembl
GRCm38.p6 Ensembl123,885,449 - 3,896,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174272
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,947,420 - 3,949,685 (+)Ensembl
GRCm38.p6 Ensembl123,897,420 - 3,899,685 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174483   ⟹   ENSMUSP00000133938
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,899,635 - 3,957,887 (+)Ensembl
GRCm38.p6 Ensembl123,849,635 - 3,907,887 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174733   ⟹   ENSMUSP00000134492
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,950,281 - 3,956,792 (+)Ensembl
GRCm38.p6 Ensembl123,900,281 - 3,906,792 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174774   ⟹   ENSMUSP00000134529
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,944,869 - 3,946,976 (+)Ensembl
GRCm38.p6 Ensembl123,894,869 - 3,896,976 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174817   ⟹   ENSMUSP00000134009
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl123,857,160 - 3,963,491 (+)Ensembl
GRCm38.p6 Ensembl123,807,160 - 3,913,491 (+)Ensembl
RefSeq Acc Id: NM_001271753   ⟹   NP_001258682
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,857,160 - 3,964,443 (+)NCBI
GRCm38123,807,160 - 3,914,443 (+)NCBI
Celera123,763,156 - 3,842,112 (+)NCBI
Sequence:
RefSeq Acc Id: NM_007872   ⟹   NP_031898
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,856,980 - 3,964,443 (+)NCBI
GRCm38123,806,980 - 3,914,443 (+)NCBI
MGSCv37123,806,980 - 3,914,443 (+)RGD
Celera123,763,156 - 3,842,112 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_153743   ⟹   NP_714965
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,941,744 - 3,964,443 (+)NCBI
GRCm38123,891,744 - 3,914,443 (+)NCBI
MGSCv37123,806,980 - 3,914,443 (+)RGD
Celera123,763,156 - 3,842,112 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514953   ⟹   XP_006515016
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,856,474 - 3,964,442 (+)NCBI
GRCm38123,806,474 - 3,914,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006514956   ⟹   XP_006515019
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,851,559 - 3,964,442 (+)NCBI
GRCm38123,801,559 - 3,914,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030246538   ⟹   XP_030102398
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,856,498 - 3,964,442 (+)NCBI
GRCm38123,806,498 - 3,914,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030246539   ⟹   XP_030102399
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,884,750 - 3,964,442 (+)NCBI
GRCm38123,834,695 - 3,914,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030246540   ⟹   XP_030102400
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,874,525 - 3,964,442 (+)NCBI
GRCm38123,824,521 - 3,914,442 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_031898   ⟸   NM_007872
- Peptide Label: isoform 1
- UniProtKB: O88508 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_714965   ⟸   NM_153743
- Peptide Label: isoform 2
- UniProtKB: O88508 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001258682   ⟸   NM_001271753
- Peptide Label: isoform 1
- UniProtKB: O88508 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515019   ⟸   XM_006514956
- Peptide Label: isoform X1
- UniProtKB: O88508 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515016   ⟸   XM_006514953
- Peptide Label: isoform X1
- UniProtKB: O88508 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030102398   ⟸   XM_030246538
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030102400   ⟸   XM_030246540
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030102399   ⟸   XM_030246539
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000106817   ⟸   ENSMUST00000111186
RefSeq Acc Id: ENSMUSP00000020991   ⟸   ENSMUST00000020991
RefSeq Acc Id: ENSMUSP00000134689   ⟸   ENSMUST00000172879
RefSeq Acc Id: ENSMUSP00000134632   ⟸   ENSMUST00000172816
RefSeq Acc Id: ENSMUSP00000134496   ⟸   ENSMUST00000172913
RefSeq Acc Id: ENSMUSP00000133869   ⟸   ENSMUST00000172509
RefSeq Acc Id: ENSMUSP00000133543   ⟸   ENSMUST00000172689
RefSeq Acc Id: ENSMUSP00000134567   ⟸   ENSMUST00000172749
RefSeq Acc Id: ENSMUSP00000133501   ⟸   ENSMUST00000172719
RefSeq Acc Id: ENSMUSP00000134492   ⟸   ENSMUST00000174733
RefSeq Acc Id: ENSMUSP00000134009   ⟸   ENSMUST00000174817
RefSeq Acc Id: ENSMUSP00000134529   ⟸   ENSMUST00000174774
RefSeq Acc Id: ENSMUSP00000134480   ⟸   ENSMUST00000174102
RefSeq Acc Id: ENSMUSP00000133938   ⟸   ENSMUST00000174483
RefSeq Acc Id: ENSMUSP00000133567   ⟸   ENSMUST00000173197
Protein Domains
ADD   PWWP   SAM-dependent MTase C5-type

Promoters
RGD ID:8677818
Promoter ID:EPDNEW_M16940
Type:initiation region
Name:Dnmt3a_2
Description:Mus musculus DNA methyltransferase 3A , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16941  EPDNEW_M16942  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38123,806,564 - 3,806,624EPDNEW
RGD ID:8677820
Promoter ID:EPDNEW_M16941
Type:initiation region
Name:Dnmt3a_1
Description:Mus musculus DNA methyltransferase 3A , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16940  EPDNEW_M16942  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38123,807,051 - 3,807,111EPDNEW
RGD ID:6846962
Promoter ID:MM_ACW:9736
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver
Transcripts:DNMT3A.OSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36123,834,461 - 3,834,961 (+)MPROMDB
RGD ID:8677822
Promoter ID:EPDNEW_M16942
Type:initiation region
Name:Dnmt3a_3
Description:Mus musculus DNA methyltransferase 3A , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16940  EPDNEW_M16941  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38123,834,805 - 3,834,865EPDNEW
RGD ID:6822857
Promoter ID:MM_KWN:11066
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung
Transcripts:NM_153743,   UC007MXD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36123,891,221 - 3,891,877 (+)MPROMDB
RGD ID:6846960
Promoter ID:MM_ACW:9741
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:DNMT3A.HSEP07,   DNMT3A.NSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36123,894,639 - 3,895,139 (+)MPROMDB
RGD ID:6848609
Promoter ID:MM_TRO:1882
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:MTR018151.12.20.10
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36123,897,301 - 3,897,801 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1261827 AgrOrtholog
Ensembl Genes ENSMUSG00000020661 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020991 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106817 UniProtKB/Swiss-Prot
  ENSMUSP00000133501 UniProtKB/TrEMBL
  ENSMUSP00000133543 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000133567 UniProtKB/TrEMBL
  ENSMUSP00000133869 UniProtKB/TrEMBL
  ENSMUSP00000133938 UniProtKB/TrEMBL
  ENSMUSP00000134009 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000134480 UniProtKB/TrEMBL
  ENSMUSP00000134492 UniProtKB/TrEMBL
  ENSMUSP00000134496 UniProtKB/TrEMBL
  ENSMUSP00000134529 UniProtKB/TrEMBL
  ENSMUSP00000134567 UniProtKB/TrEMBL
  ENSMUSP00000134632 UniProtKB/TrEMBL
  ENSMUSP00000134689 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020991 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111186 UniProtKB/Swiss-Prot
  ENSMUST00000172509 UniProtKB/TrEMBL
  ENSMUST00000172689 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000172719 UniProtKB/TrEMBL
  ENSMUST00000172749 UniProtKB/TrEMBL
  ENSMUST00000172816 UniProtKB/TrEMBL
  ENSMUST00000172879 UniProtKB/TrEMBL
  ENSMUST00000172913 UniProtKB/TrEMBL
  ENSMUST00000173197 UniProtKB/TrEMBL
  ENSMUST00000174102 UniProtKB/TrEMBL
  ENSMUST00000174483 UniProtKB/TrEMBL
  ENSMUST00000174733 UniProtKB/TrEMBL
  ENSMUST00000174774 UniProtKB/TrEMBL
  ENSMUST00000174817 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro ADD UniProtKB/Swiss-Prot
  ADD_DNMT3A UniProtKB/Swiss-Prot
  C5_DNA_meth_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MeTfrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT3_ADD UniProtKB/Swiss-Prot
  DNMT3A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13435 UniProtKB/Swiss-Prot
MGD MGI:1261827 ENTREZGENE
NCBI Gene 13435 ENTREZGENE
PANTHER PTHR23068:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ADD_DNMT3 UniProtKB/Swiss-Prot
  DNA_methylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnmt3a PhenoGen
PROSITE ADD UniProtKB/Swiss-Prot
  C5_MTASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_MT_C5 UniProtKB/Swiss-Prot
SMART PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DNM3A_MOUSE UniProtKB/Swiss-Prot
  G3UX07_MOUSE UniProtKB/TrEMBL
  G3UX63_MOUSE UniProtKB/TrEMBL
  G3UXY2_MOUSE UniProtKB/TrEMBL
  G3UY43_MOUSE UniProtKB/TrEMBL
  G3UZF8_MOUSE UniProtKB/TrEMBL
  G3UZG8_MOUSE UniProtKB/TrEMBL
  G3UZH2_MOUSE UniProtKB/TrEMBL
  G3UZK0_MOUSE UniProtKB/TrEMBL
  G3UZN5_MOUSE UniProtKB/TrEMBL
  G3UZU0_MOUSE UniProtKB/TrEMBL
  G3UZY8_MOUSE UniProtKB/TrEMBL
  O88508 ENTREZGENE
  Q3TYD7_MOUSE UniProtKB/TrEMBL
  Q3UWR0_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TZK8 UniProtKB/Swiss-Prot
  Q3UH24 UniProtKB/Swiss-Prot
  Q8CJ60 UniProtKB/Swiss-Prot
  Q922J0 UniProtKB/Swiss-Prot
  Q9CSE1 UniProtKB/Swiss-Prot