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Gene: Dnmt3a (DNA methyltransferase 3A) Mus musculus
Symbol: Dnmt3a
Name: DNA methyltransferase 3A
Description: Exhibits DNA (cytosine-5-)-methyltransferase activity; DNA binding activity; and chromatin binding activity. Involved in several processes, including DNA methylation; regulation of gene expression by genetic imprinting; and regulation of nucleobase-containing compound metabolic process. Localizes to the chromosome and cytoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia; myelodysplastic syndrome; precursor T-lymphoblastic lymphoma/leukemia; precursor lymphoblastic lymphoma/leukemia; and stomach cancer. Is expressed in several structures, including 1st branchial arch; central nervous system; limb mesenchyme; reproductive system; and urethra. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AU015806; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase MmuIIIA; DNA MTase MmuIIIA; m.MmuIIIA; MmuIIIA; W91664
Homo sapiens (human) : DNMT3A (DNA methyltransferase 3 alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnmt3a (DNA methyltransferase 3 alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnmt3a (DNA methyltransferase 3 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : DNMT3A (DNA methyltransferase 3 alpha)
Canis lupus familiaris (dog) : DNMT3A (DNA methyltransferase 3 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnmt3a (DNA methyltransferase 3 alpha)
Sus scrofa (pig) : DNMT3A (DNA methyltransferase 3 alpha)
more info ...
Related Pseudogenes: Dnmt3a-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl123,806,007 - 3,914,443 (+)Ensembl
GRCm38123,801,559 - 3,914,443 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37123,806,980 - 3,914,443 (+)NCBIGRCm37mm9NCBIm37
MGSCv36123,835,027 - 3,914,455 (+)NCBImm8
Celera123,763,156 - 3,842,112 (+)NCBICelera
Cytogenetic Map12 A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dnmt3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620920
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.