(+)-catechin multiple interactions ISO RGD:69423 6480464 Catechin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:23365609 (-)-cotinine multiple interactions ISO RGD:69423 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 (-)-demecolcine decreases expression ISO RGD:69473 6480464 Demecolcine results in decreased expression of SREBF1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:69473 6480464 epigallocatechin gallate results in decreased expression of SREBF1 mRNA CTD PMID:20816778 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 (2,4,5-trichlorophenoxy)acetic acid increases expression EXP 6480464 2 more ... CTD PMID:18579281 (25R)-cholest-5-ene-3beta,26-diol decreases expression ISO RGD:69423 6480464 27-hydroxycholesterol results in decreased expression of SREBF1 mRNA, 27-hydroxycholesterol results in decreased expression of SREBF1 protein CTD PMID:28167099 (R)-carnitine multiple interactions ISO RGD:69423 6480464 Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 (R)-lipoic acid multiple interactions ISO RGD:69423 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22464149 (S)-nicotine decreases expression ISO RGD:69473 6480464 Nicotine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:31622651 (S)-nicotine multiple interactions ISO RGD:69423 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 (S)-nicotine increases expression ISO RGD:69423 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:29155039 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of SREBF1 mRNA CTD PMID:18925944 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:69423 6480464 o, p'-DDT affects the expression of SREBF1 mRNA CTD PMID:17984292 1,10-phenanthroline multiple interactions ISO RGD:69473 6480464 [1 more ... CTD PMID:21355074 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose multiple interactions EXP 6480464 beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA], beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 protein] CTD PMID:30721698 1,3-dichloropropan-2-ol increases expression EXP 6480464 1 more ... CTD PMID:24333398 , PMID:30092300 1,3-dichloropropan-2-ol multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 1,3-dichloropropan-2-ol increases expression ISO RGD:69473 6480464 1 more ... CTD PMID:29305303 1,3-dichloropropan-2-ol multiple interactions ISO RGD:69473 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions ISO RGD:69473 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 1-benzylpiperazine increases expression ISO RGD:69423 6480464 N-benzylpiperazine results in increased expression of SREBF1 mRNA CTD PMID:26821219 1-naphthyl isothiocyanate decreases expression ISO RGD:69423 6480464 1-Naphthylisothiocyanate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 , PMID:25380136 1-naphthyl isothiocyanate increases expression ISO RGD:69423 6480464 1-Naphthylisothiocyanate results in increased expression of SREBF1 mRNA CTD PMID:30723492 14-Deoxy-11,12-didehydroandrographolide multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:30248417 17alpha-ethynylestradiol decreases expression ISO RGD:69423 6480464 Ethinyl Estradiol results in decreased expression of SREBF1 mRNA CTD PMID:17108234 17alpha-ethynylestradiol multiple interactions EXP 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 17beta-estradiol multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 , PMID:31730885 17beta-estradiol decreases expression ISO RGD:69423 6480464 Estradiol results in decreased expression of SREBF1 mRNA, Estradiol results in decreased expression of SREBF1 protein CTD PMID:26164745 17beta-estradiol multiple interactions EXP 6480464 1 more ... CTD PMID:21768169 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:69473 6480464 Dihydrotestosterone results in increased expression of SREBF1 mRNA CTD PMID:16541421 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:20005886 , PMID:21851831 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 2 more ... CTD PMID:21851831 more ... 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:69473 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SREBF1 mRNA CTD PMID:24058054 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69423 6480464 Tetrachlorodibenzodioxin results in increased expression of SREBF1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69423 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA CTD PMID:21215274 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SREBF1 mRNA CTD PMID:21846477 , PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of SREBF1 protein CTD PMID:18295293 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 2 more ... CTD PMID:16054899 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69473 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA CTD PMID:20106945 2,3,7,8-Tetrachlorodibenzofuran multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [2 more ... CTD PMID:34097992 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2 more ... CTD PMID:34097992 2,4-dinitrotoluene affects expression ISO RGD:69423 6480464 2, 4-dinitrotoluene affects the expression of SREBF1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO RGD:69423 6480464 2, 6-dinitrotoluene affects the expression of SREBF1 mRNA CTD PMID:21346803 2-amino-2-deoxy-D-glucopyranose 6-phosphate decreases expression EXP 6480464 glucosamine 6-phosphate results in decreased expression of SREBF1 protein CTD PMID:19427183 2-deoxy-D-glucose increases expression EXP 6480464 Deoxyglucose results in increased expression of SREBF1 mRNA CTD PMID:10913129 2-naphthylamine decreases expression ISO RGD:69473 6480464 2-Naphthylamine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 22-Hydroxycholesterol increases expression EXP 6480464 22-hydroxycholesterol results in increased expression of SREBF1 mRNA, 22-hydroxycholesterol results in increased expression of SREBF1 protein CTD PMID:16763553 22-Hydroxycholesterol multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 22-Hydroxycholesterol multiple interactions EXP 6480464 22-hydroxycholesterol promotes the reaction [SREBF1 protein binds to ALDH1A1 promoter], 22-hydroxycholesterol promotes the reaction [SREBF1 protein binds to ALDH1A2 promoter] CTD PMID:16763553 25-hydroxycholesterol increases expression EXP 6480464 25-hydroxycholesterol results in increased expression of SREBF1 protein CTD PMID:19260826 25-hydroxycholesterol multiple interactions ISO RGD:69473 6480464 [25-hydroxycholesterol co-treated with Cholesterol] results in decreased cleavage of SREBF1 protein CTD PMID:27324795 26-hydroxycholesterol decreases expression ISO RGD:69423 6480464 27-hydroxycholesterol results in decreased expression of SREBF1 mRNA, 27-hydroxycholesterol results in decreased expression of SREBF1 protein CTD PMID:28167099 28-Homobrassinolide increases expression ISO RGD:69423 6480464 homobrassinolide results in increased expression of SREBF1 mRNA CTD PMID:21491949 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23994337 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:69423 6480464 3 more ... CTD PMID:26693162 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of SREBF1 mRNA CTD PMID:30496566 3,3',5-triiodo-L-thyronine decreases activity ISO RGD:69423 6480464 Triiodothyronine results in decreased activity of SREBF1 protein CTD PMID:23209300 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:69473 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA, rosemarinic acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA] CTD PMID:33476690 3,3',5-triiodo-L-thyronine decreases expression ISO RGD:69423 6480464 Triiodothyronine results in decreased expression of SREBF1 mRNA CTD PMID:23209300 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:69423 6480464 SIRT1 protein affects the reaction [Triiodothyronine results in decreased activity of SREBF1 protein], SIRT1 protein affects the reaction [Triiodothyronine results in decreased expression of SREBF1 mRNA] CTD PMID:23209300 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:11101056 more ... 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:26200599 more ... 3-phenylprop-2-enal multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of SREBF1 mRNA] CTD PMID:21401097 3-phenylprop-2-enal decreases expression EXP 6480464 cinnamaldehyde results in decreased expression of SREBF1 mRNA CTD PMID:21401097 3H-1,2-dithiole-3-thione increases expression ISO RGD:69423 6480464 1, 2-dithiol-3-thione results in increased expression of SREBF1 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression ISO RGD:69423 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SREBF1 mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SREBF1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:69473 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SREBF1 mRNA CTD PMID:27003841 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SREBF1 mRNA CTD PMID:30145421 4-nonylphenol increases expression ISO RGD:69423 6480464 4-nonylphenol results in increased expression of SREBF1 mRNA CTD PMID:24388992 4-phenylbutyric acid multiple interactions ISO RGD:69423 6480464 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of SREBF1 mRNA] CTD PMID:25398788 4-tert-Octylphenol decreases expression ISO RGD:69423 6480464 4-tert-octylphenol results in decreased expression of SREBF1 mRNA, 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 5-aza-2'-deoxycytidine multiple interactions ISO RGD:69473 6480464 [Decitabine co-treated with Depsipeptides] results in increased expression of SREBF1 mRNA CTD PMID:17064661 5-fluorouracil affects expression ISO RGD:69473 6480464 Fluorouracil affects the expression of SREBF1 mRNA CTD PMID:34151400 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime decreases expression ISO RGD:69473 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expression ISO RGD:69473 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:27180240 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO RGD:69473 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 , PMID:30611723 8'-apo-beta,psi-caroten-8'-al increases expression ISO RGD:69473 6480464 apocarotenal results in increased expression of SREBF1 mRNA CTD PMID:17034753 8-Br-cAMP decreases expression ISO RGD:69473 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SREBF1 mRNA CTD PMID:22079614 9-cis,11-trans-octadecadienoic acid affects expression EXP 6480464 cis-9, trans-11-conjugated linoleic acid affects the expression of SREBF1 mRNA CTD PMID:17327424 9-cis-retinoic acid multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 acadesine multiple interactions ISO RGD:69473 6480464 acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of SREBF1 protein] CTD PMID:33508418 acetaldehyde increases expression ISO RGD:69473 6480464 Acetaldehyde results in increased expression of SREBF1 protein CTD PMID:12612910 acetaldehyde increases expression ISO RGD:69423 6480464 Acetaldehyde results in increased expression of SREBF1 protein CTD PMID:12036955 acetamide decreases expression ISO RGD:69423 6480464 acetamide results in decreased expression of SREBF1 mRNA CTD PMID:31881176 acetylleucyl-leucyl-norleucinal multiple interactions ISO RGD:69473 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [SGA 360 results in increased degradation of and results in decreased expression of SREBF1 protein] CTD PMID:31225620 acrolein multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF1 mRNA CTD PMID:32699268 acrylamide multiple interactions EXP 6480464 Acrylamide promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SREBF1 protein], Acrylamide promotes the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:30409764 aflatoxin B1 affects expression ISO RGD:69473 6480464 Aflatoxin B1 affects the expression of SREBF1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:69473 6480464 Aflatoxin B1 results in decreased expression of SREBF1 mRNA CTD PMID:21641981 , PMID:27153756 aflatoxin B1 multiple interactions ISO RGD:69423 6480464 [sulforaphane co-treated with Aflatoxin B1] affects the expression of SREBF1 mRNA CTD PMID:25450479 alcohol increases expression EXP 6480464 Alcohols results in increased expression of SREBF1 protein CTD PMID:28803762 alcohol multiple interactions EXP 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of SREBF1 protein], Glutathione inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 aldehydo-D-glucosamine 6-phosphate decreases expression EXP 6480464 glucosamine 6-phosphate results in decreased expression of SREBF1 protein CTD PMID:19427183 aldehydo-D-glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... aldehydo-D-glucose multiple interactions EXP 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... aldehydo-D-glucose increases expression ISO RGD:69423 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 aldehydo-D-glucose multiple interactions ISO RGD:69423 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 aldehydo-D-glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 aldrin increases expression EXP 6480464 Aldrin results in increased expression of SREBF1 mRNA CTD PMID:18579281 all-trans-retinoic acid multiple interactions EXP 6480464 AGN 193109 inhibits the reaction [Tretinoin results in increased expression of SREBF1 mRNA] CTD PMID:16505366 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of SREBF1 mRNA CTD PMID:16505366 alliin multiple interactions ISO RGD:69473 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 allopurinol multiple interactions ISO RGD:69473 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23647015 allopurinol multiple interactions ISO RGD:69423 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] more ... CTD PMID:23647015 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of SREBF1 mRNA CTD PMID:10913129 alpha-linolenic acid decreases expression ISO RGD:69423 6480464 alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA CTD PMID:14563831 alpha-pinene multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF1 mRNA CTD PMID:32699268 amiodarone decreases expression ISO RGD:69423 6480464 Amiodarone results in decreased expression of SREBF1 mRNA CTD PMID:17202758 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of SREBF1 mRNA CTD PMID:28962527 amiodarone increases expression ISO RGD:69473 6480464 Amiodarone results in increased expression of SREBF1 mRNA CTD PMID:32651653 amitriptyline multiple interactions ISO RGD:69473 6480464 Amitriptyline results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 amlexanox multiple interactions EXP 6480464 amlexanox inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA] CTD PMID:32905826 amlexanox decreases expression EXP 6480464 amlexanox results in decreased expression of SREBF1 mRNA CTD PMID:32905826 ammonium chloride affects expression ISO RGD:69423 6480464 Ammonium Chloride affects the expression of SREBF1 mRNA CTD PMID:16483693 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:69473 6480464 pyrazolanthrone inhibits the reaction [FGF7 protein results in increased expression of SREBF1 protein] CTD PMID:16162944 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 aristolochic acid decreases expression ISO RGD:69473 6480464 aristolochic acid I results in decreased expression of SREBF1 mRNA CTD PMID:33212167 arsane multiple interactions EXP 6480464 [APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 protein CTD PMID:22719926 arsenic atom multiple interactions EXP 6480464 [APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 protein CTD PMID:22719926 arsenous acid multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 , PMID:30237538 arsenous acid decreases expression ISO RGD:69473 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 more ... atazanavir sulfate multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 atorvastatin calcium multiple interactions ISO RGD:69423 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein], Atorvastatin inhibits the reaction [Fructose results in increased activity of SREBF1 protein] CTD PMID:19053045 , PMID:32259528 atrazine multiple interactions EXP 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA CTD PMID:24440342 Azaspiracid increases expression ISO RGD:69473 6480464 azaspiracid results in increased expression of SREBF1 mRNA CTD PMID:28939011 AZD4547 decreases expression ISO RGD:69473 6480464 AZD4547 results in decreased expression of SREBF1 protein CTD PMID:26853465 azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with Dietary Fats] affects the expression of SREBF1 mRNA CTD PMID:24726979 baicalein decreases expression EXP 6480464 baicalein results in decreased expression of SREBF1 protein CTD PMID:24560969 benzene affects expression ISO RGD:69423 6480464 Benzene affects the expression of SREBF1 mRNA CTD PMID:15878777 benzene increases expression ISO RGD:69473 6480464 Benzene results in increased expression of SREBF1 mRNA CTD PMID:19162166 benzo[a]pyrene increases mutagenesis ISO RGD:69473 6480464 Benzo(a)pyrene results in increased mutagenesis of SREBF1 gene CTD PMID:25435355 benzo[a]pyrene multiple interactions ISO RGD:69473 6480464 Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]], Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]] CTD PMID:31730885 benzo[a]pyrene affects methylation ISO RGD:69473 6480464 Benzo(a)pyrene affects the methylation of SREBF1 promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:69473 6480464 Benzo(a)pyrene results in decreased methylation of SREBF1 3' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:69423 6480464 Benzo(a)pyrene results in increased expression of SREBF1 mRNA CTD PMID:26303333 benzo[a]pyrene decreases expression ISO RGD:69473 6480464 Benzo(a)pyrene results in decreased expression of SREBF1 mRNA CTD PMID:18247414 more ... benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene affects the reaction [GCLM gene mutant form results in decreased expression of SREBF1 mRNA] more ... CTD PMID:24291350 , PMID:31730885 benzylpenicillin multiple interactions EXP 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 mRNA] more ... CTD PMID:20564506 berberine decreases expression ISO RGD:69473 6480464 Berberine results in decreased expression of SREBF1 mRNA CTD PMID:26478571 beta-carotene increases expression ISO RGD:69473 6480464 beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 beta-D-glucosamine 6-sulfate decreases expression EXP 6480464 glucosamine 6-O-sulfate results in decreased expression of SREBF1 mRNA, glucosamine 6-O-sulfate results in decreased expression of SREBF1 protein CTD PMID:19520133 beta-hexachlorocyclohexane decreases expression EXP 6480464 beta-hexachlorocyclohexane results in decreased expression of SREBF1 mRNA CTD PMID:25270620 beta-hexachlorocyclohexane increases expression ISO RGD:69473 6480464 beta-hexachlorocyclohexane results in increased expression of SREBF1 mRNA, beta-hexachlorocyclohexane results in increased expression of SREBF1 protein CTD PMID:27203212 beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of SREBF1 mRNA CTD PMID:23994337 betulin decreases expression ISO RGD:69473 6480464 betulin results in decreased expression of SREBF1 protein CTD PMID:27447558 betulin decreases cleavage ISO RGD:69473 6480464 betulin results in decreased cleavage of SREBF1 protein CTD PMID:29950559 betulin multiple interactions ISO RGD:69473 6480464 [Gefitinib co-treated with betulin] results in decreased expression of SREBF1 protein, betulin affects the reaction [BRAF protein affects the reaction [Vemurafenib results in decreased cleavage of SREBF1 protein]] CTD PMID:27447558 , PMID:29950559 bexarotene increases expression ISO RGD:69423 6480464 bexarotene results in increased expression of SREBF1 mRNA CTD PMID:23292798 bexarotene increases expression ISO RGD:69473 6480464 Bexarotene results in increased expression of SREBF1 mRNA CTD PMID:32123961 bexarotene multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 , PMID:32123961 bezafibrate multiple interactions ISO RGD:69473 6480464 SREBF1 protein inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 bezafibrate multiple interactions ISO RGD:69423 6480464 Bezafibrate inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of SREBF1 mRNA, Bezafibrate results in increased expression of SREBF1 protein CTD PMID:19124612 bezafibrate multiple interactions EXP 6480464 [Bezafibrate results in decreased expression of SREBF1] which results in decreased abundance of Triglycerides more ... CTD PMID:19124612 bezafibrate decreases expression EXP 6480464 Bezafibrate results in decreased expression of SREBF1 mRNA, Bezafibrate results in decreased expression of SREBF1 protein CTD PMID:19124612 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:23756648 , PMID:30722647 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:69423 6480464 Diethylhexyl Phthalate results in decreased expression of SREBF1 protein CTD PMID:30597186 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:69423 6480464 Diethylhexyl Phthalate promotes the reaction [Dietary Fats results in increased expression of SREBF1 mRNA], Diethylhexyl Phthalate promotes the reaction [SREBF1 protein binds to SLC2A2 promoter] CTD PMID:30597186 , PMID:33166671 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SREBF1 mRNA alternative form, bisphenol A affects the expression of SREBF1 protein CTD PMID:21932408 bisphenol A affects expression ISO RGD:69473 6480464 bisphenol A affects the expression of SREBF1 mRNA CTD PMID:30903817 bisphenol A decreases expression ISO RGD:69423 6480464 bisphenol A results in decreased expression of SREBF1 mRNA CTD PMID:28657538 bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of SREBF1 promoter CTD PMID:27502578 , PMID:28796629 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of SREBF1 promoter CTD PMID:27334623 bisphenol A increases response to substance EXP 6480464 SREBF1 mRNA results in increased susceptibility to bisphenol A CTD PMID:27502578 bisphenol A increases expression ISO RGD:69423 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:20019905 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SREBF1 mRNA CTD PMID:24959901 bisphenol A multiple interactions ISO RGD:69423 6480464 bisphenol A inhibits the reaction [SREBF1 protein binds to CPT1A promoter] more ... CTD PMID:25112833 more ... bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:23756648 more ... bisphenol A increases expression ISO RGD:69473 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:25047013 more ... bisphenol A multiple interactions ISO RGD:69473 6480464 MIR192 mRNA inhibits the reaction [bisphenol A results in increased expression of SREBF1 mRNA] more ... CTD PMID:27014939 , PMID:28483554 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:21932408 more ... Bisphenol A diglycidyl ether decreases expression ISO RGD:69423 6480464 2, 2-bis(4-glycidyloxyphenyl)propane results in decreased expression of SREBF1 protein CTD PMID:22726273 boric acid multiple interactions EXP 6480464 boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:28285642 bromobenzene decreases expression ISO RGD:69423 6480464 bromobenzene results in decreased expression of SREBF1 mRNA CTD PMID:32479839 buspirone decreases expression ISO RGD:69423 6480464 Buspirone results in decreased expression of SREBF1 mRNA CTD PMID:24136188 buta-1,3-diene decreases expression EXP 6480464 1, 3-butadiene results in decreased expression of SREBF1 mRNA CTD PMID:21147608 butyric acid multiple interactions ISO RGD:69473 6480464 Butyric Acid inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF1 mRNA] CTD PMID:29751049 butyric acid multiple interactions EXP 6480464 Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA] CTD PMID:29751049 C60 fullerene increases expression ISO RGD:69423 6480464 fullerene C60 results in increased expression of SREBF1 mRNA CTD PMID:19167457 Cacalol decreases expression ISO RGD:69473 6480464 cacalol results in decreased expression of SREBF1 protein CTD PMID:20665104 Cacalol multiple interactions ISO RGD:69473 6480464 cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter] CTD PMID:20665104 cadmium atom multiple interactions ISO RGD:69423 6480464 [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein, myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 cadmium atom decreases expression ISO RGD:69423 6480464 Cadmium results in decreased expression of SREBF1 mRNA CTD PMID:28315714 cadmium dichloride decreases expression ISO RGD:69423 6480464 Cadmium Chloride results in decreased expression of SREBF1 mRNA CTD PMID:25993096 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SREBF1 mRNA CTD PMID:26352046 caffeine increases expression ISO RGD:69423 6480464 Caffeine results in increased expression of SREBF1 mRNA, Caffeine results in increased expression of SREBF1 protein CTD PMID:30776459 calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of SREBF1 mRNA CTD PMID:16368784 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of SREBF1 mRNA CTD PMID:31052254 carbendazim increases expression EXP 6480464 carbendazim results in increased expression of SREBF1 mRNA CTD PMID:26071454 CARBENOXOLONE affects activity ISO RGD:69423 6480464 Carbenoxolone affects the activity of SREBF1 protein CTD PMID:31077719 CARBENOXOLONE multiple interactions ISO RGD:69423 6480464 Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SREBF1 mRNA] CTD PMID:31077719 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25620056 carbon nanotube increases expression ISO RGD:69473 6480464 Nanotubes, Carbon results in increased expression of SREBF1 mRNA CTD PMID:31047983 carvedilol multiple interactions ISO RGD:69423 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:22413959 cerivastatin multiple interactions ISO RGD:69473 6480464 SREBF1 protein inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 chenodeoxycholic acid decreases expression ISO RGD:69473 6480464 Chenodeoxycholic Acid results in decreased expression of SREBF1 mRNA CTD PMID:16269825 chenodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 chenodeoxycholic acid multiple interactions EXP 6480464 Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 protein] CTD PMID:27773935 chitosan multiple interactions ISO RGD:69423 6480464 [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA], Chitosan inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:28987369 chloroethene increases expression EXP 6480464 Vinyl Chloride results in increased expression of SREBF1 mRNA CTD PMID:18579281 chlorohydrocarbon increases expression ISO RGD:69473 6480464 Hydrocarbons, Chlorinated results in increased expression of SREBF1 mRNA CTD PMID:27203212 chlorpyrifos multiple interactions ISO RGD:69423 6480464 Dietary Fats promotes the reaction [Chlorpyrifos results in increased expression of SREBF1 mRNA] CTD PMID:33994353 cholate multiple interactions ISO RGD:69423 6480464 [cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of SREBF1 mRNA CTD PMID:25814186 cholesterol multiple interactions EXP 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA, [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 cholesterol multiple interactions ISO RGD:69473 6480464 [25-hydroxycholesterol co-treated with Cholesterol] results in decreased cleavage of SREBF1 protein CTD PMID:27324795 choline multiple interactions EXP 6480464 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2 more ... CTD PMID:19593819 more ... choline multiple interactions ISO RGD:69423 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA, geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of SREBF1 mRNA CTD PMID:18353800 cis-caffeic acid multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 cisplatin multiple interactions ISO RGD:69473 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SREBF1 mRNA CTD PMID:27392435 citalopram multiple interactions ISO RGD:69473 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 clofazimine increases expression ISO RGD:69423 6480464 Clofazimine results in increased expression of SREBF1 mRNA CTD PMID:31393584 clofibrate decreases expression ISO RGD:69423 6480464 Clofibrate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 clofibrate increases expression ISO RGD:69473 6480464 Clofibrate results in increased expression of SREBF1 mRNA CTD PMID:27089845 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of SREBF1 mRNA CTD PMID:23811191 clofibrate multiple interactions EXP 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA] CTD PMID:17585979 clomipramine multiple interactions ISO RGD:69473 6480464 Clomipramine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 clozapine increases expression ISO RGD:69473 6480464 Clozapine results in increased expression of SREBF1 mRNA CTD PMID:17052361 clozapine increases expression EXP 6480464 Clozapine results in increased expression of SREBF1 mRNA, Clozapine results in increased expression of SREBF1 protein CTD PMID:19682446 , PMID:20564506 clozapine multiple interactions EXP 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 mRNA], Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 protein] CTD PMID:20564506 cobalt dichloride decreases expression ISO RGD:69473 6480464 cobaltous chloride results in decreased expression of SREBF1 mRNA CTD PMID:19320972 cobalt dichloride increases expression ISO RGD:69473 6480464 cobaltous chloride results in increased expression of SREBF1 mRNA CTD PMID:19376846 , PMID:22917661 copper atom multiple interactions ISO RGD:69423 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of SREBF1 mRNA more ... CTD PMID:23112546 , PMID:25813056 copper atom decreases expression EXP 6480464 Copper results in decreased expression of SREBF1 mRNA CTD PMID:17205981 copper atom affects localization ISO RGD:69423 6480464 Copper deficiency affects the localization of SREBF1 protein CTD PMID:11110846 copper atom multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of SREBF1 mRNA CTD PMID:20971185 , PMID:24690739 copper(0) multiple interactions ISO RGD:69423 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of SREBF1 mRNA more ... CTD PMID:23112546 , PMID:25813056 copper(0) affects localization ISO RGD:69423 6480464 Copper deficiency affects the localization of SREBF1 protein CTD PMID:11110846 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of SREBF1 mRNA CTD PMID:17205981 copper(0) multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of SREBF1 mRNA CTD PMID:20971185 , PMID:24690739 corticosterone multiple interactions ISO RGD:69423 6480464 [Corticosterone co-treated with oleoyl-estrone] affects the expression of SREBF1 mRNA CTD PMID:19545626 corticosterone multiple interactions EXP 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 cortisol multiple interactions ISO RGD:69473 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA more ... CTD PMID:30776459 , PMID:33476690 cortisol increases expression ISO RGD:69473 6480464 Hydrocortisone results in increased expression of SREBF1 mRNA CTD PMID:30776459 Cuprizon increases expression ISO RGD:69423 6480464 Cuprizone results in increased expression of SREBF1 mRNA CTD PMID:26577399 , PMID:27523638 curcumin decreases expression ISO RGD:69423 6480464 Curcumin results in decreased expression of SREBF1 mRNA CTD PMID:27208389 curcumin affects expression EXP 6480464 Curcumin affects the expression of SREBF1 mRNA, Curcumin affects the expression of SREBF1 protein CTD PMID:27208389 cyclosporin A decreases expression ISO RGD:69473 6480464 Cyclosporine results in decreased expression of SREBF1 mRNA CTD PMID:20106945 more ... cyclosporin A multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 cyclosporin A increases expression ISO RGD:69473 6480464 Cyclosporine results in increased expression of SREBF1 mRNA CTD PMID:25562108 cyhalothrin increases expression ISO RGD:69423 6480464 cyhalothrin results in increased expression of SREBF1 mRNA CTD PMID:27348886 D-gluconic acid multiple interactions ISO RGD:69423 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 D-glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... D-glucose multiple interactions EXP 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... D-glucose multiple interactions ISO RGD:69423 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 D-glucose increases expression ISO RGD:69423 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 D-glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 D-penicillamine multiple interactions EXP 6480464 Penicillamine promotes the reaction [ATP7B protein mutant form results in decreased expression of SREBF1 mRNA] CTD PMID:22945834 dabrafenib decreases cleavage ISO RGD:69473 6480464 dabrafenib results in decreased cleavage of SREBF1 protein CTD PMID:29950559 dabrafenib multiple interactions ISO RGD:69473 6480464 [BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein CTD PMID:29950559 dapagliflozin multiple interactions ISO RGD:69423 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein], dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein] CTD PMID:32259528 DDE multiple interactions ISO RGD:69473 6480464 Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:26200599 DDE increases expression ISO RGD:69473 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of SREBF1 protein CTD PMID:27203212 deoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 deoxypodophyllotoxin multiple interactions ISO RGD:69473 6480464 deoxypodophyllotoxin inhibits the reaction [TO-901317 results in increased expression of SREBF1 mRNA] more ... CTD PMID:30148990 deoxypodophyllotoxin multiple interactions EXP 6480464 deoxypodophyllotoxin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:30148990 depsipeptide multiple interactions ISO RGD:69473 6480464 [decitabine co-treated with Depsipeptides] results in increased expression of SREBF1 mRNA CTD PMID:17064661 depsipeptide increases expression ISO RGD:69473 6480464 Depsipeptides results in increased expression of SREBF1 mRNA CTD PMID:17064661 desferrioxamine B multiple interactions ISO RGD:69473 6480464 [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] CTD PMID:34648812 desmosterol increases expression EXP 6480464 Desmosterol results in increased expression of SREBF1 mRNA, Desmosterol results in increased expression of SREBF1 protein CTD PMID:19260826 dexamethasone multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:11101056 more ... dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SREBF1 mRNA CTD PMID:31053639 dexamethasone multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 more ... dexamethasone increases expression ISO RGD:69473 6480464 Dexamethasone results in increased expression of SREBF1 mRNA CTD PMID:25047013 , PMID:27003841 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:22138249 Diallyl sulfide multiple interactions ISO RGD:69473 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:22138249 diarsenic trioxide decreases expression ISO RGD:69473 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 more ... diarsenic trioxide multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 , PMID:30237538 dibutyl phthalate decreases expression ISO RGD:69423 6480464 Dibutyl Phthalate results in decreased expression of SREBF1 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO RGD:69473 6480464 [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein more ... CTD PMID:33508418 dibutyl phthalate multiple interactions ISO RGD:69423 6480464 Dibutyl Phthalate promotes the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:33508418 dibutyl phthalate increases expression ISO RGD:69423 6480464 Dibutyl Phthalate results in increased expression of SREBF1 protein CTD PMID:33508418 dibutyl phthalate increases expression ISO RGD:69473 6480464 Dibutyl Phthalate results in increased expression of SREBF1 protein CTD PMID:33508418 dichloroacetic acid increases expression EXP 6480464 Dichloroacetic Acid results in increased expression of SREBF1 mRNA CTD PMID:28962523 diethyl maleate decreases expression ISO RGD:69423 6480464 diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 diethylstilbestrol multiple interactions EXP 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Diethylstilbestrol results in increased expression of SREBF1 protein] CTD PMID:22710028 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of SREBF1 mRNA, Diethylstilbestrol results in increased expression of SREBF1 protein CTD PMID:22710028 dihydroartemisinin multiple interactions ISO RGD:69423 15036816 Dihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver] RGD dihydroartemisinin multiple interactions ISO RGD:69473 6480464 [artenimol co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] more ... CTD PMID:27939985 dimethyl sulfoxide increases expression ISO RGD:69423 15092090 DMSO increases expression of Srebf1 mRNA in rat liver, reaction inhibited by INT-767 RGD dioxygen multiple interactions ISO RGD:69473 6480464 [FV-429 compound co-treated with Oxygen deficiency] affects the expression of SREBF1 protein more ... CTD PMID:24503013 , PMID:34648812 dioxygen increases expression ISO RGD:69473 6480464 Oxygen deficiency results in increased expression of SREBF1 mRNA, Oxygen deficiency results in increased expression of SREBF1 protein CTD PMID:34648812 dioxygen decreases expression ISO RGD:69473 6480464 Oxygen deficiency results in decreased expression of SREBF1 protein CTD PMID:24503013 disodium selenite decreases methylation EXP 6480464 Sodium Selenite results in decreased methylation of SREBF1 exon CTD PMID:28810182 disodium selenite multiple interactions ISO RGD:69423 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 disodium selenite increases expression EXP 6480464 Sodium Selenite results in increased expression of SREBF1 mRNA CTD PMID:28810182 disulfiram multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 dorsomorphin multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:23319015 more ... dorsomorphin multiple interactions ISO RGD:69423 6480464 dorsomorphin inhibits the reaction [Resveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of SREBF1 mRNA]] CTD PMID:24633463 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of SREBF1 mRNA] CTD PMID:21401097 doxorubicin decreases expression ISO RGD:69473 6480464 Doxorubicin results in decreased expression of SREBF1 mRNA CTD PMID:29803840 doxorubicin decreases expression ISO RGD:69423 6480464 Doxorubicin results in decreased expression of SREBF1 mRNA CTD PMID:32289291 efavirenz decreases expression ISO RGD:69473 6480464 efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:28810182 elemental selenium multiple interactions ISO RGD:69423 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 elemental selenium increases expression ISO RGD:69423 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:19022953 endosulfan decreases expression ISO RGD:69423 6480464 Endosulfan results in decreased expression of SREBF1 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:69473 6480464 entinostat results in increased expression of SREBF1 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SREBF1 mRNA CTD PMID:27188386 erythromycin A multiple interactions EXP 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 erythromycin A increases expression EXP 6480464 Erythromycin results in increased expression of SREBF1 mRNA CTD PMID:27503388 erythromycin estolate decreases expression ISO RGD:69423 6480464 Erythromycin Estolate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 ethanol multiple interactions EXP 6480464 5 more ... CTD PMID:12036955 more ... ethanol decreases expression ISO RGD:69473 6480464 Ethanol results in decreased expression of SREBF1 protein CTD PMID:28062356 ethanol increases expression ISO RGD:69423 15036816 ethanol increases expression of Srebf1 mRNA and protein in liver RGD ethanol increases expression ISO RGD:69423 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:12036955 more ... ethanol increases expression EXP 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:18620774 more ... ethanol multiple interactions ISO RGD:69473 6480464 5 more ... CTD PMID:22138249 more ... ethanol increases expression ISO RGD:69473 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:22138249 more ... ethanol affects localization ISO RGD:69423 6480464 Ethanol affects the localization of SREBF1 protein CTD PMID:19371623 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of SREBF1 mRNA CTD PMID:22173916 , PMID:28882574 ethanol decreases expression ISO RGD:69423 6480464 Ethanol results in decreased expression of SREBF1 mRNA CTD PMID:16098508 ethanol increases activity EXP 6480464 Ethanol results in increased activity of SREBF1 protein CTD PMID:18620774 ethanol multiple interactions ISO RGD:69423 6480464 [Dietary Fats co-treated with Ethanol] results in increased expression of SREBF1 mRNA more ... CTD PMID:18239056 more ... ethyl methanesulfonate decreases expression ISO RGD:69473 6480464 Ethyl Methanesulfonate results in decreased expression of SREBF1 mRNA CTD PMID:23649840 ezetimibe decreases expression ISO RGD:69473 6480464 Ezetimibe results in decreased expression of SREBF1 mRNA CTD PMID:16177187 fenofibrate multiple interactions ISO RGD:69473 6480464 Fenofibrate inhibits the reaction [Fatty Acids more ... CTD PMID:24735863 fenofibrate multiple interactions ISO RGD:69423 6480464 [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] CTD PMID:26973390 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of SREBF1 mRNA CTD PMID:23063693 fenofibrate multiple interactions EXP 6480464 Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA] more ... CTD PMID:19593819 , PMID:23063693 folic acid affects localization EXP 6480464 Folic Acid affects the localization of SREBF1 protein CTD PMID:25733650 formaldehyde decreases expression ISO RGD:69473 6480464 Formaldehyde results in decreased expression of SREBF1 mRNA CTD PMID:23649840 fructose multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Fructose affects the localization of SREBF1 protein alternative form] more ... CTD PMID:15066988 , PMID:22698815 fructose increases expression EXP 6480464 Fructose results in increased expression of SREBF1 mRNA, Fructose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... fructose affects localization EXP 6480464 Fructose affects the localization of SREBF1 protein alternative form CTD PMID:22698815 fructose increases expression ISO RGD:69423 6480464 Fructose results in increased expression of SREBF1 mRNA, Fructose results in increased expression of SREBF1 protein CTD PMID:11934685 more ... fructose multiple interactions ISO RGD:69423 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein] more ... CTD PMID:17188681 more ... fructose affects response to substance EXP 6480464 SREBF1 promoter SNP affects the susceptibility to Fructose CTD PMID:15123654 fumonisin B1 decreases expression EXP 6480464 fumonisin B1 results in decreased expression of SREBF1 mRNA CTD PMID:16221962 furan decreases expression ISO RGD:69423 6480464 furan results in decreased expression of SREBF1 mRNA CTD PMID:26194646 gadolinium trichloride multiple interactions ISO RGD:69423 6480464 gadolinium chloride inhibits the reaction [[Fructose co-treated with Copper deficiency] results in increased expression of SREBF1 protein] CTD PMID:25813056 galactose increases expression EXP 6480464 Galactose results in increased expression of SREBF1 mRNA CTD PMID:10913129 gamma-hexachlorocyclohexane decreases expression ISO RGD:69423 6480464 Hexachlorocyclohexane results in decreased expression of SREBF1 mRNA CTD PMID:17785943 Ganoderic acid A multiple interactions EXP 6480464 [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF1 mRNA, [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF1 protein CTD PMID:29852127 Ganoderic acid A decreases expression ISO RGD:69473 6480464 ganoderic acid A results in decreased expression of SREBF1 mRNA, ganoderic acid A results in decreased expression of SREBF1 protein CTD PMID:29852127 Gastrodin multiple interactions EXP 6480464 gastrodin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26634892 gefitinib multiple interactions ISO RGD:69473 6480464 [Gefitinib co-treated with betulin] results in decreased expression of SREBF1 protein CTD PMID:27447558 genistein multiple interactions EXP 6480464 [Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of SREBF1 mRNA CTD PMID:27181934 genistein multiple interactions ISO RGD:69473 6480464 Genistein inhibits the reaction [TO-901317 results in increased expression of SREBF1 protein] CTD PMID:29702089 gentamycin increases expression ISO RGD:69423 6480464 Gentamicins results in increased expression of SREBF1 mRNA CTD PMID:33387578 geraniol multiple interactions ISO RGD:69423 6480464 geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 ginsenoside Re multiple interactions EXP 6480464 ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:21971952 ginsenoside Re decreases expression ISO RGD:69473 6480464 ginsenoside Re results in decreased expression of SREBF1 mRNA CTD PMID:21971952 Ginsenoside Rh4 multiple interactions EXP 6480464 ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA] CTD PMID:33359794 glucagon multiple interactions EXP 6480464 Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA], Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SREBF1 mRNA] CTD PMID:29988851 glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... glucose multiple interactions EXP 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... glucose multiple interactions ISO RGD:69423 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 glucose increases expression ISO RGD:69423 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 glycerol 2-phosphate multiple interactions ISO RGD:69473 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 glycochenodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glyphosate increases expression EXP 6480464 glyphosate results in increased expression of SREBF1 mRNA CTD PMID:31374489 gold atom multiple interactions ISO RGD:69473 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA CTD PMID:28433809 gold(0) multiple interactions ISO RGD:69473 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA CTD PMID:28433809 guggulsterone multiple interactions ISO RGD:69423 15036816 Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver]] RGD guggulsterone multiple interactions EXP 6480464 pregna-4 more ... CTD PMID:27773935 GW 3965 increases expression ISO RGD:69423 6480464 GW 3965 results in increased expression of SREBF1 mRNA CTD PMID:28315714 GW 3965 multiple interactions EXP 6480464 GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA], GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] CTD PMID:31421115 GW 3965 increases expression ISO RGD:69473 6480464 GW 3965 results in increased expression of SREBF1 mRNA, GW 3965 results in increased expression of SREBF1 protein CTD PMID:16107141 more ... GW 3965 multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA more ... CTD PMID:23651738 more ... GW 4064 decreases expression ISO RGD:69473 6480464 GW 4064 results in decreased expression of SREBF1 mRNA CTD PMID:16269825 GW 4064 multiple interactions ISO RGD:69473 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA CTD PMID:30611723 GW 6471 multiple interactions ISO RGD:69473 6480464 GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein], GW 6471 inhibits the reaction [Dibutyl Phthalate results in increased expression of SREBF1 protein] CTD PMID:33508418 GW 7647 multiple interactions ISO RGD:69473 6480464 [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA CTD PMID:30611723 herbacetin multiple interactions EXP 6480464 herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:29653099 hexadecanoic acid multiple interactions ISO RGD:69473 6480464 ATG5 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]] more ... CTD PMID:25943029 , PMID:30208301 hexadecanoic acid multiple interactions EXP 6480464 acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA] more ... CTD PMID:30208301 more ... hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of SREBF1 mRNA more ... CTD PMID:29414781 more ... hexadecanoic acid multiple interactions ISO RGD:69423 6480464 [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein more ... CTD PMID:26190035 , PMID:26854922 hexadecanoic acid increases expression ISO RGD:69473 6480464 Palmitic Acid results in increased expression of SREBF1 protein CTD PMID:25943029 , PMID:30208301 Honokiol decreases expression ISO RGD:69423 6480464 honokiol results in decreased expression of SREBF1 mRNA CTD PMID:19371623 Honokiol multiple interactions ISO RGD:69423 6480464 honokiol inhibits the reaction [Ethanol affects the localization of SREBF1 protein] more ... CTD PMID:19371623 Honokiol affects localization ISO RGD:69423 6480464 honokiol affects the localization of SREBF1 protein CTD PMID:19371623 hydrazines decreases expression EXP 6480464 Hydrazines results in decreased expression of SREBF1 mRNA CTD PMID:21647536 hydrogen peroxide increases expression ISO RGD:69473 6480464 Hydrogen Peroxide results in increased expression of SREBF1 mRNA CTD PMID:29317476 imidacloprid increases expression EXP 6480464 imidacloprid results in increased expression of SREBF1 mRNA CTD PMID:27960282 imipramine multiple interactions ISO RGD:69473 6480464 Imipramine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 indole-3-methanol affects expression ISO RGD:69423 6480464 indole-3-carbinol affects the expression of SREBF1 mRNA CTD PMID:21396975 kahweol decreases expression ISO RGD:69473 6480464 kahweol results in decreased expression of SREBF1 mRNA, kahweol results in decreased expression of SREBF1 protein CTD PMID:30205135 kahweol multiple interactions ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [kahweol results in decreased expression of SREBF1 protein], kahweol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SREBF1 protein] CTD PMID:30205135 ketamine increases expression ISO RGD:69423 6480464 Ketamine results in increased expression of SREBF1 mRNA CTD PMID:20080153 ketotifen increases expression ISO RGD:69473 6480464 Ketotifen results in increased expression of SREBF1 mRNA CTD PMID:27089845 L-ascorbic acid multiple interactions ISO RGD:69473 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 L-methionine multiple interactions EXP 6480464 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2 more ... CTD PMID:19593819 more ... L-methionine multiple interactions ISO RGD:69423 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA, geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 L-serine decreases expression ISO RGD:69473 6480464 Serine results in decreased expression of SREBF1 mRNA CTD PMID:29098664 linoleic acid decreases expression ISO RGD:69423 6480464 Linoleic Acid results in decreased expression of SREBF1 mRNA CTD PMID:14563831 lipoic acid multiple interactions ISO RGD:69423 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22464149 lipopolysaccharide affects localization EXP 6480464 Lipopolysaccharides affects the localization of SREBF1 protein CTD PMID:21689150 lipopolysaccharide multiple interactions ISO RGD:69473 6480464 Butyric Acid inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF1 mRNA] CTD PMID:29751049 lipopolysaccharide increases expression ISO RGD:69473 6480464 Lipopolysaccharides results in increased expression of SREBF1 mRNA, Lipopolysaccharides results in increased expression of SREBF1 protein CTD PMID:29751049 , PMID:33677747 lipopolysaccharide multiple interactions EXP 6480464 Melatonin inhibits the reaction [Lipopolysaccharides affects the localization of SREBF1 protein] CTD PMID:21689150 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of SREBF1 mRNA CTD PMID:16847310 lithocholic acid multiple interactions EXP 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of SREBF1 mRNA] CTD PMID:20359477 lithocholic acid decreases expression EXP 6480464 Lithocholic Acid results in decreased expression of SREBF1 mRNA CTD PMID:20359477 losartan multiple interactions ISO RGD:69423 6480464 Losartan inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein] more ... CTD PMID:19109942 , PMID:25398788 lovastatin multiple interactions EXP 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of SREBF1 mRNA CTD PMID:29852127 lovastatin increases expression ISO RGD:69473 6480464 Lovastatin results in increased expression of SREBF1 mRNA CTD PMID:32739440 luteolin multiple interactions EXP 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of SREBF1 mRNA] CTD PMID:32407927 LY294002 multiple interactions ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF7 protein results in increased expression of SREBF1 protein] more ... CTD PMID:16162944 , PMID:30205135 LY294002 decreases expression ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SREBF1 protein CTD PMID:30205135 LY294002 multiple interactions ISO RGD:69423 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849 , PMID:25398788 magnesium atom multiple interactions ISO RGD:69423 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 Magnolol affects localization ISO RGD:69423 6480464 magnolol affects the localization of SREBF1 protein CTD PMID:19371623 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Lipopolysaccharides affects the localization of SREBF1 protein] CTD PMID:21689150 metformin multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 metformin multiple interactions ISO RGD:69423 6480464 Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA], Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein] CTD PMID:31100278 metformin decreases expression ISO RGD:69423 6480464 Metformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 methyl methanesulfonate decreases expression ISO RGD:69473 6480464 Methyl Methanesulfonate results in decreased expression of SREBF1 mRNA CTD PMID:23649840 mevastatin increases cleavage EXP 6480464 mevastatin results in increased cleavage of SREBF1 protein CTD PMID:16330322 mevastatin multiple interactions EXP 6480464 EIF2S1 protein modified form inhibits the reaction [mevastatin results in increased cleavage of SREBF1 protein] CTD PMID:16330322 mevastatin decreases expression ISO RGD:69423 6480464 mevastatin results in decreased expression of SREBF1 protein CTD PMID:17526932 microcystin-LR decreases expression EXP 6480464 cyanoginosin LR results in decreased expression of SREBF1 mRNA CTD PMID:17654400 miquelianin multiple interactions ISO RGD:69423 6480464 quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA], quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 mirtazapine multiple interactions ISO RGD:69473 6480464 mirtazapine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 mono(2-ethylhexyl) phthalate increases expression ISO RGD:69473 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SREBF1 mRNA CTD PMID:23118965 mono(2-ethylhexyl) phthalate affects expression EXP 6480464 mono-(2-ethylhexyl)phthalate affects the expression of SREBF1 mRNA CTD PMID:27181934 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of SREBF1 mRNA CTD PMID:27181934 monocrotophos increases expression ISO RGD:69423 6480464 Monocrotophos results in increased expression of SREBF1 mRNA CTD PMID:32267039 monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of SREBF1 mRNA, Sodium Glutamate results in increased expression of SREBF1 protein CTD PMID:19724016 monosodium L-glutamate multiple interactions EXP 6480464 3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of SREBF1 mRNA] more ... CTD PMID:19001666 more ... monosodium L-glutamate affects expression ISO RGD:69423 6480464 Sodium Glutamate affects the expression of SREBF1 mRNA CTD PMID:31077719 monosodium L-glutamate multiple interactions ISO RGD:69423 6480464 Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SREBF1 mRNA] CTD PMID:31077719 monosodium L-glutamate decreases expression ISO RGD:69423 6480464 Sodium Glutamate results in decreased expression of SREBF1 mRNA CTD PMID:26092479 Muraglitazar increases expression ISO RGD:69423 6480464 muraglitazar results in increased expression of SREBF1 mRNA CTD PMID:21515302 myricetin multiple interactions ISO RGD:69423 6480464 myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:69473 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF1 protein] CTD PMID:26125464 N-methylformamide decreases expression EXP 6480464 methylformamide analog results in decreased expression of SREBF1 mRNA, methylformamide results in decreased expression of SREBF1 mRNA CTD PMID:17040096 N-methylnicotinate multiple interactions EXP 6480464 trigonelline inhibits the reaction [[Cholesterol more ... CTD PMID:30208301 N-methylnicotinate multiple interactions ISO RGD:69473 6480464 ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]], trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] CTD PMID:30208301 N-nitrosodiethylamine decreases expression ISO RGD:69473 6480464 Diethylnitrosamine results in decreased expression of SREBF1 mRNA CTD PMID:21527772 N-nitrosodimethylamine decreases expression ISO RGD:69423 6480464 Dimethylnitrosamine results in decreased expression of SREBF1 mRNA CTD PMID:25380136 N-Nitrosopyrrolidine decreases expression ISO RGD:69473 6480464 N-Nitrosopyrrolidine results in decreased expression of SREBF1 mRNA CTD PMID:32234424 naloxone decreases expression ISO RGD:69423 6480464 Naloxone results in decreased expression of SREBF1 mRNA CTD PMID:17522070 naringin multiple interactions EXP 6480464 naringin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22198281 nefazodone decreases expression ISO RGD:69423 6480464 nefazodone results in decreased expression of SREBF1 mRNA CTD PMID:24136188 nefazodone multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 nelfinavir affects localization ISO RGD:69473 6480464 Nelfinavir affects the localization of SREBF1 protein CTD PMID:21355074 nelfinavir increases expression ISO RGD:69473 6480464 Nelfinavir results in increased expression of SREBF1 protein CTD PMID:16940799 nelfinavir decreases expression ISO RGD:69473 6480464 Nelfinavir results in decreased expression of SREBF1 protein alternative form CTD PMID:21355074 nelfinavir multiple interactions ISO RGD:69473 6480464 Nelfinavir inhibits the reaction [MBTPS2 protein results in increased cleavage of and results in increased activity of SREBF1 protein] CTD PMID:21355074 nelfinavir decreases cleavage ISO RGD:69473 6480464 Nelfinavir results in decreased cleavage of SREBF1 protein CTD PMID:21355074 nelfinavir increases stability ISO RGD:69473 6480464 Nelfinavir results in increased stability of SREBF1 protein CTD PMID:21355074 nevirapine increases expression ISO RGD:69473 6480464 Nevirapine results in increased expression of SREBF1 mRNA CTD PMID:21619898 nevirapine decreases expression ISO RGD:69423 6480464 Nevirapine metabolite results in decreased expression of SREBF1 mRNA CTD PMID:23947594 nicotinamide multiple interactions ISO RGD:69473 6480464 Niacinamide inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of SREBF1 protein]] CTD PMID:23319015 nicotine decreases expression ISO RGD:69473 6480464 Nicotine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 nicotine increases expression EXP 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:31622651 nicotine multiple interactions ISO RGD:69423 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 nicotine increases expression ISO RGD:69423 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:29155039 nimesulide decreases expression ISO RGD:69423 6480464 nimesulide results in decreased expression of SREBF1 mRNA CTD PMID:24136188 O-methyleugenol decreases expression ISO RGD:69473 6480464 methyleugenol results in decreased expression of SREBF1 mRNA CTD PMID:32234424 obeticholic acid multiple interactions ISO RGD:69423 15036816 Obeticholic acid inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver] RGD obeticholic acid decreases expression ISO RGD:69473 6480464 obeticholic acid results in decreased expression of SREBF1 mRNA CTD PMID:27939613 obeticholic acid multiple interactions ISO RGD:69473 6480464 obeticholic acid inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:27939985 olanzapine multiple interactions EXP 6480464 olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA], olanzapine results in increased activity of and results in increased expression of SREBF1 protein CTD PMID:17651982 olanzapine increases expression EXP 6480464 olanzapine results in increased expression of SREBF1 mRNA CTD PMID:17651982 olaparib multiple interactions EXP 6480464 [Dietary Fats co-treated with olaparib] results in decreased expression of SREBF1 mRNA CTD PMID:27984176 oleanolic acid multiple interactions ISO RGD:69473 6480464 Oleanolic Acid promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA] CTD PMID:28796629 oleic acid increases expression ISO RGD:69423 6480464 Oleic Acid results in increased expression of SREBF1 mRNA CTD PMID:23395669 oleic acid increases expression ISO RGD:69473 6480464 Oleic Acid results in increased expression of SREBF1 mRNA, Oleic Acid results in increased expression of SREBF1 protein CTD PMID:31730885 oleic acid multiple interactions EXP 6480464 [N-(oxo-5 more ... CTD PMID:30165350 oleic acid multiple interactions ISO RGD:69423 6480464 [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein more ... CTD PMID:23395669 more ... oleic acid decreases expression ISO RGD:69473 6480464 Oleic Acid results in decreased expression of SREBF1 mRNA, Oleic Acid results in decreased expression of SREBF1 protein CTD PMID:15949695 more ... oleic acid multiple interactions ISO RGD:69473 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:23603006 more ... oleuropein multiple interactions ISO RGD:69423 6480464 oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of SREBF1 protein] CTD PMID:27019295 Olmesartan medoxomil decreases expression ISO RGD:69423 6480464 Olmesartan Medoxomil results in decreased expression of SREBF1 mRNA CTD PMID:18501344 orlistat decreases expression ISO RGD:69473 6480464 Orlistat results in decreased expression of SREBF1 protein CTD PMID:32045588 orlistat multiple interactions ISO RGD:69473 6480464 Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased expression of SREBF1 protein] CTD PMID:32045588 oroxylin A multiple interactions ISO RGD:69473 6480464 5 more ... CTD PMID:29476730 oroxylin A multiple interactions EXP 6480464 5 more ... CTD PMID:29476730 ozone decreases expression ISO RGD:69423 6480464 Ozone results in decreased expression of SREBF1 mRNA CTD PMID:25838073 ozone multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA more ... CTD PMID:32699268 p-menthan-3-ol decreases expression ISO RGD:69473 6480464 Menthol results in decreased expression of SREBF1 mRNA CTD PMID:26760959 p-tert-Amylphenol decreases expression ISO RGD:69423 6480464 4-tert-octylphenol results in decreased expression of SREBF1 mRNA, 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 paclitaxel multiple interactions ISO RGD:69473 6480464 [FV-429 compound co-treated with Paclitaxel] inhibits the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] more ... CTD PMID:34648812 paracetamol multiple interactions EXP 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA] CTD PMID:17585979 paracetamol multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 paracetamol decreases expression ISO RGD:69473 6480464 Acetaminophen results in decreased expression of SREBF1 mRNA CTD PMID:29067470 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of SREBF1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:69423 6480464 Acetaminophen results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... Paxilline multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA, [CD 3254 co-treated with paxilline] results in increased expression of SREBF1 mRNA CTD PMID:32123961 Paxilline increases expression ISO RGD:69473 6480464 paxilline results in increased expression of SREBF1 mRNA CTD PMID:32123961 PD 168393 multiple interactions ISO RGD:69423 6480464 PD168393 inhibits the reaction [Glucose results in increased activity of and results in increased cleavage of SREBF1 protein] CTD PMID:22031849 penconazole increases expression EXP 6480464 penconazole results in increased expression of SREBF1 mRNA CTD PMID:31733957 perfluorododecanoic acid increases expression ISO RGD:69423 6480464 perfluorododecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:23353032 perfluorononanoic acid increases expression ISO RGD:69423 6480464 perfluoro-n-nonanoic acid results in increased expression of SREBF1 mRNA CTD PMID:22648072 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:69423 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF1 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:69473 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF1 mRNA CTD PMID:32253466 perfluorooctane-1-sulfonic acid increases cleavage EXP 6480464 perfluorooctane sulfonic acid results in increased cleavage of SREBF1 protein CTD PMID:28288859 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of SREBF1 mRNA CTD PMID:26548598 perfluorooctane-1-sulfonic acid increases expression ISO RGD:69423 6480464 perfluorooctane sulfonic acid results in increased expression of SREBF1 mRNA CTD PMID:18692542 , PMID:21723365 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of SREBF1 mRNA CTD PMID:25092180 , PMID:30657992 perfluorooctanoic acid decreases expression ISO RGD:69473 6480464 perfluorooctanoic acid results in decreased expression of SREBF1 mRNA CTD PMID:32253466 perfluorooctanoic acid multiple interactions EXP 6480464 [perfluorooctanoic acid co-treated with Dietary Fats] results in increased expression of SREBF1 mRNA CTD PMID:30711707 perfluorooctanoic acid increases cleavage EXP 6480464 perfluorooctanoic acid results in increased cleavage of SREBF1 protein CTD PMID:25092180 perfluorooctanoic acid increases expression ISO RGD:69423 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:21723365 perfluorooctanoic acid increases expression ISO RGD:69473 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:21723365 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:25092180 permethrin multiple interactions EXP 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 phenformin decreases expression ISO RGD:69423 6480464 Phenformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA] CTD PMID:19482888 phenobarbital decreases expression ISO RGD:69473 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:21768169 phenobarbital multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA] more ... CTD PMID:21768169 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of SREBF1 mRNA CTD PMID:23091169 phenobarbital decreases expression ISO RGD:69423 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:19162173 , PMID:28520973 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:19482888 picolinic acid affects localization EXP 6480464 picolinic acid affects the localization of SREBF1 protein CTD PMID:16870493 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SREBF1 mRNA more ... CTD PMID:15777286 more ... pirinixic acid increases expression ISO RGD:69423 6480464 pirinixic acid results in increased expression of SREBF1 mRNA CTD PMID:19162173 pirinixic acid multiple interactions ISO RGD:69423 6480464 [[[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides, [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein CTD PMID:19248225 pirinixic acid increases cleavage EXP 6480464 pirinixic acid results in increased cleavage of SREBF1 protein CTD PMID:15777286 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of SREBF1 mRNA CTD PMID:17426115 , PMID:18301758 platycodin D multiple interactions ISO RGD:69473 6480464 dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of SREBF1 mRNA]] more ... CTD PMID:23319015 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:69423 6480464 Pregnenolone Carbonitrile results in decreased expression of SREBF1 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of SREBF1 mRNA CTD PMID:28903501 pregnenolone 16alpha-carbonitrile multiple interactions EXP 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of SREBF1 mRNA] CTD PMID:20359477 progesterone multiple interactions EXP 6480464 1 more ... CTD PMID:21768169 progesterone multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 progesterone increases expression ISO RGD:69423 6480464 Progesterone results in increased expression of SREBF1 mRNA CTD PMID:20726854 propamocarb decreases expression EXP 6480464 propamocarb results in decreased expression of SREBF1 mRNA CTD PMID:29137890 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of SREBF1 mRNA CTD PMID:21278054 propiconazole multiple interactions ISO RGD:69473 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of SREBF1 mRNA CTD PMID:30989312 propiconazole decreases expression ISO RGD:69473 6480464 propiconazole results in decreased expression of SREBF1 mRNA CTD PMID:30989312 , PMID:33575850 puerarin multiple interactions EXP 6480464 puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of SREBF1 mRNA] CTD PMID:31273855 Pyridostigmine bromide multiple interactions EXP 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 quercetin multiple interactions ISO RGD:69423 6480464 Quercetin inhibits the reaction [Glucose results in increased expression of SREBF1 protein] more ... CTD PMID:23647015 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SREBF1 protein] more ... CTD PMID:18586010 more ... quercetin increases expression ISO RGD:69473 6480464 Quercetin results in increased expression of SREBF1 mRNA CTD PMID:21632981 quercetin multiple interactions ISO RGD:69473 6480464 Quercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of SREBF1 mRNA] more ... CTD PMID:23647015 , PMID:24648896 raffinose decreases expression ISO RGD:69473 6480464 Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 raffinose decreases expression EXP 6480464 Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 raloxifene multiple interactions ISO RGD:69473 6480464 [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA CTD PMID:19059307 reactive oxygen species affects expression ISO RGD:69473 6480464 Reactive Oxygen Species affects the expression of SREBF1 mRNA CTD PMID:25800948 resveratrol decreases expression EXP 6480464 [resveratrol results in decreased expression of SREBF1 mRNA] which results in decreased expression of FASN mRNA more ... CTD PMID:22659145 , PMID:23090186 resveratrol decreases expression ISO RGD:69473 6480464 Resveratrol results in decreased expression of SREBF1 mRNA CTD PMID:30776459 resveratrol decreases expression ISO RGD:69423 6480464 resveratrol results in decreased expression of SREBF1 mRNA CTD PMID:23209300 resveratrol multiple interactions EXP 6480464 [resveratrol co-treated with Dietary Fats] results in decreased expression of SREBF1 mRNA more ... CTD PMID:18755807 more ... resveratrol increases expression ISO RGD:69473 6480464 resveratrol results in increased expression of SREBF1 protein modified form CTD PMID:22153697 resveratrol multiple interactions ISO RGD:69473 6480464 [Resveratrol results in increased activity of and results in increased cleavage of [SREBF1 protein co-treated with SREBF2 protein]] which results in increased expression of LDLR mRNA more ... CTD PMID:22153697 more ... resveratrol multiple interactions ISO RGD:69423 6480464 [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] more ... CTD PMID:18239056 more ... risperidone multiple interactions EXP 6480464 Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 mRNA], Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 protein] CTD PMID:20564506 risperidone increases expression EXP 6480464 Risperidone results in increased expression of SREBF1 mRNA, Risperidone results in increased expression of SREBF1 protein CTD PMID:20564506 ritonavir multiple interactions EXP 6480464 Ritonavir promotes the reaction [[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SREBF1 protein] CTD PMID:11101056 rotenone increases expression ISO RGD:69473 6480464 Rotenone results in increased expression of SREBF1 mRNA CTD PMID:17651460 rotenone decreases expression ISO RGD:69423 6480464 Rotenone results in decreased expression of SREBF1 mRNA CTD PMID:19693701 , PMID:28374803 S-allylcysteine decreases expression ISO RGD:69473 6480464 S-allylcysteine results in decreased expression of SREBF1 protein CTD PMID:23465592 S-allylcysteine multiple interactions ISO RGD:69473 6480464 dorsomorphin inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein] more ... CTD PMID:23465592 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression ISO RGD:69423 6480464 Buthionine Sulfoximine results in decreased expression of SREBF1 mRNA CTD PMID:20482862 salubrinal multiple interactions ISO RGD:69423 6480464 salubrinal inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] more ... CTD PMID:25398788 SB 431542 multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SREBF1 mRNA CTD PMID:27188386 scopoletin multiple interactions ISO RGD:69423 6480464 Scopoletin inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:26115886 selenium atom increases expression ISO RGD:69423 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:19022953 selenium atom multiple interactions ISO RGD:69423 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 selenium atom increases expression EXP 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:28810182 selenomethionine decreases methylation EXP 6480464 Selenomethionine results in decreased methylation of SREBF1 exon CTD PMID:28810182 selenomethionine increases expression EXP 6480464 Selenomethionine results in increased expression of SREBF1 mRNA CTD PMID:28810182 silibinin multiple interactions ISO RGD:69473 6480464 fatostatin promotes the reaction [Silybin results in decreased cleavage of SREBF1 protein], Silybin results in decreased cleavage of and results in increased phosphorylation of SREBF1 protein CTD PMID:25294820 silibinin decreases response to substance ISO RGD:69473 6480464 SREBF1 protein results in decreased susceptibility to Silybin CTD PMID:25294820 simvastatin decreases expression ISO RGD:69423 6480464 Simvastatin results in decreased expression of SREBF1 mRNA CTD PMID:25055962 simvastatin increases localization ISO RGD:69473 6480464 Simvastatin results in increased localization of SREBF1 protein CTD PMID:17655842 sirolimus decreases expression EXP 6480464 Sirolimus results in decreased expression of SREBF1 mRNA CTD PMID:15358118 sirtinol multiple interactions ISO RGD:69473 6480464 sirtinol inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein] CTD PMID:23465592 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SREBF1 mRNA CTD PMID:23221991 more ... sodium arsenite decreases expression ISO RGD:69423 6480464 sodium arsenite results in decreased expression of SREBF1 mRNA CTD PMID:32593899 sodium arsenite affects expression ISO RGD:69473 6480464 sodium arsenite affects the expression of SREBF1 protein CTD PMID:27932253 sodium cholate multiple interactions EXP 6480464 [Cholesterol more ... CTD PMID:27394961 sodium dichromate affects expression ISO RGD:69423 6480464 sodium bichromate affects the expression of SREBF1 mRNA CTD PMID:22110744 starch multiple interactions ISO RGD:69423 6480464 Starch analog inhibits the reaction [Rapeseed Oil metabolite results in increased expression of SREBF1 mRNA] CTD PMID:27363782 stavudine multiple interactions ISO RGD:69423 6480464 Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 stavudine increases expression ISO RGD:69423 6480464 Stavudine results in increased expression of SREBF1 mRNA CTD PMID:18299183 streptozocin multiple interactions ISO RGD:69423 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA more ... CTD PMID:23647015 more ... streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA more ... CTD PMID:29420703 more ... streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of SREBF1 protein CTD PMID:22031849 , PMID:29420703 streptozocin decreases expression ISO RGD:69423 6480464 Streptozocin results in decreased expression of SREBF1 protein CTD PMID:28822685 streptozocin increases expression ISO RGD:69423 6480464 Streptozocin results in increased expression of SREBF1 mRNA, Streptozocin results in increased expression of SREBF1 protein CTD PMID:23647015 sucrose multiple interactions EXP 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA, [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 sucrose multiple interactions ISO RGD:69423 6480464 [Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 mRNA more ... CTD PMID:31175915 sulforaphane multiple interactions ISO RGD:69423 6480464 [sulforaphane co-treated with Aflatoxin B1] affects the expression of SREBF1 mRNA CTD PMID:25450479 sulforaphane decreases expression ISO RGD:69473 6480464 sulforaphane results in decreased expression of SREBF1 mRNA CTD PMID:31838189 sulforaphane multiple interactions ISO RGD:69473 6480464 sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA] CTD PMID:28796629 sunitinib increases expression ISO RGD:69473 6480464 Sunitinib results in increased expression of SREBF1 mRNA CTD PMID:31533062 tamoxifen multiple interactions ISO RGD:69473 6480464 [Tamoxifen co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA CTD PMID:19059307 tartrazine multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 tauroursodeoxycholic acid multiple interactions ISO RGD:69423 6480464 ursodoxicoltaurine inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] CTD PMID:25398788 tebuconazole multiple interactions ISO RGD:69473 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of SREBF1 mRNA CTD PMID:30989312 tebuconazole increases expression ISO RGD:69473 6480464 tebuconazole results in increased expression of SREBF1 mRNA CTD PMID:30989312 testosterone increases expression EXP 6480464 Testosterone results in increased expression of SREBF1 mRNA CTD PMID:16579987 testosterone cypionate multiple interactions EXP 6480464 [testosterone 17 beta-cypionate co-treated with Dietary Fats] results in increased expression of SREBF1 mRNA CTD PMID:29704577 testosterone cypionate increases expression EXP 6480464 testosterone 17 beta-cypionate results in increased expression of SREBF1 mRNA CTD PMID:29704577 tetrachloromethane decreases expression ISO RGD:69423 6480464 Carbon Tetrachloride results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SREBF1 mRNA CTD PMID:27339419 , PMID:31919559 tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of SREBF1 mRNA CTD PMID:16917069 tetracycline increases expression ISO RGD:69473 6480464 Tetracycline results in increased expression of SREBF1 mRNA CTD PMID:27089845 tetracycline decreases expression ISO RGD:69423 6480464 Tetracycline results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... tetramethylpyrazine multiple interactions EXP 6480464 NFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA]] more ... CTD PMID:27837167 thapsigargin multiple interactions ISO RGD:69473 6480464 Thapsigargin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] CTD PMID:23106379 thapsigargin multiple interactions ISO RGD:69423 6480464 Thapsigargin promotes the reaction [SREBF1 protein binds to TGFB1 promoter] CTD PMID:25398788 thapsigargin increases cleavage ISO RGD:69423 6480464 Thapsigargin results in increased cleavage of SREBF1 protein CTD PMID:25398788 theophylline decreases expression ISO RGD:69423 6480464 Theophylline results in decreased expression of SREBF1 mRNA CTD PMID:17522070 thioacetamide decreases expression ISO RGD:69423 6480464 Thioacetamide results in decreased expression of SREBF1 mRNA CTD PMID:23411599 thymol multiple interactions EXP 6480464 Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:26680107 thymol sulfate(1-) multiple interactions EXP 6480464 Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:26680107 topiramate increases expression ISO RGD:69423 6480464 topiramate results in increased expression of SREBF1 mRNA CTD PMID:16979414 trametinib multiple interactions ISO RGD:69473 6480464 trametinib affects the reaction [[BRAF protein affects the susceptibility to Vemurafenib] which affects the cleavage of SREBF1 protein] CTD PMID:29950559 trans-caffeic acid multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 tributyl phosphate increases expression ISO RGD:69473 6480464 tributyl phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 tributylstannane multiple interactions ISO RGD:69473 6480464 tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:25932594 tributylstannane increases expression ISO RGD:69473 6480464 tributyltin results in increased expression of SREBF1 mRNA CTD PMID:28011154 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of SREBF1 mRNA CTD PMID:23322813 , PMID:25932594 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of SREBF1 mRNA CTD PMID:25270620 Tributyltin oxide increases expression ISO RGD:69423 6480464 bis(tri-n-butyltin)oxide results in increased expression of SREBF1 mRNA CTD PMID:17553608 triclosan affects expression ISO RGD:69473 6480464 Triclosan affects the expression of SREBF1 mRNA CTD PMID:31714634 triolein multiple interactions EXP 6480464 Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]], Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] CTD PMID:15066988 triphenyl phosphate increases expression ISO RGD:69473 6480464 triphenyl phosphate results in increased expression of SREBF1 mRNA CTD PMID:28934090 , PMID:30966736 tris(2-butoxyethyl) phosphate increases expression ISO RGD:69473 6480464 tris(2-butoxyethyl) phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 Tris(2-ethylhexyl) phosphate increases expression ISO RGD:69473 6480464 tris(2-ethylhexyl)phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 troglitazone multiple interactions ISO RGD:69423 6480464 [[[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides, [troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein CTD PMID:19248225 troglitazone multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with troglitazone co-treated with INS protein] results in increased expression of SREBF1 mRNA CTD PMID:27003841 troglitazone decreases expression ISO RGD:69423 6480464 troglitazone results in decreased expression of SREBF1 mRNA CTD PMID:10900012 troglitazone decreases expression ISO RGD:69473 6480464 troglitazone results in decreased expression of SREBF1 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO RGD:69423 6480464 trovafloxacin results in decreased expression of SREBF1 mRNA CTD PMID:24136188 tunicamycin increases cleavage EXP 6480464 Tunicamycin results in increased cleavage of SREBF1 protein CTD PMID:22414386 tunicamycin multiple interactions EXP 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of SREBF1 mRNA] CTD PMID:32407927 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of SREBF1 mRNA CTD PMID:32407927 tunicamycin increases cleavage ISO RGD:69423 6480464 Tunicamycin results in increased cleavage of SREBF1 protein CTD PMID:25398788 tunicamycin multiple interactions ISO RGD:69473 6480464 HNRNPA1 mutant form inhibits the reaction [Tunicamycin results in increased expression of SREBF1 protein], Tunicamycin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] CTD PMID:23106379 tunicamycin increases expression ISO RGD:69423 6480464 Tunicamycin results in increased expression of SREBF1 protein CTD PMID:23106379 tunicamycin multiple interactions ISO RGD:69423 6480464 HNRNPA1 mutant form inhibits the reaction [Tunicamycin results in increased expression of SREBF1 protein], Tunicamycin promotes the reaction [SREBF1 protein binds to TGFB1 promoter] CTD PMID:23106379 , PMID:25398788 tunicamycin increases expression ISO RGD:69473 6480464 Tunicamycin results in increased expression of SREBF1 protein CTD PMID:23106379 tyrphostin AG 1478 multiple interactions ISO RGD:69423 6480464 RTKI cpd inhibits the reaction [Glucose results in increased activity of and results in increased cleavage of SREBF1 protein] CTD PMID:22031849 valdecoxib decreases expression ISO RGD:69423 6480464 valdecoxib results in decreased expression of SREBF1 mRNA CTD PMID:24136188 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of SREBF1 mRNA CTD PMID:17292431 , PMID:17963808 valproic acid multiple interactions ISO RGD:69473 6480464 NR1H3 protein affects the reaction [Valproic Acid results in increased expression of SREBF1 mRNA], NR1H3 protein promotes the reaction [Valproic Acid results in increased expression of SREBF1 mRNA] CTD PMID:30003287 valproic acid decreases expression ISO RGD:69473 6480464 Valproic Acid results in decreased expression of SREBF1 mRNA CTD PMID:29154799 valproic acid affects expression ISO RGD:69473 6480464 Valproic Acid affects the expression of SREBF1 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:69473 6480464 Valproic Acid results in increased expression of SREBF1 mRNA, Valproic Acid results in increased expression of SREBF1 protein CTD PMID:25716160 more ... vemurafenib multiple interactions ISO RGD:69473 6480464 [BRAF protein affects the susceptibility to Vemurafenib] which affects the cleavage of SREBF1 protein more ... CTD PMID:29950559 vemurafenib decreases expression ISO RGD:69473 6480464 Vemurafenib results in decreased expression of SREBF1 mRNA alternative form CTD PMID:29950559 vemurafenib decreases cleavage ISO RGD:69473 6480464 Vemurafenib results in decreased cleavage of SREBF1 protein CTD PMID:29950559 vincristine decreases expression ISO RGD:69473 6480464 Vincristine results in decreased expression of SREBF1 mRNA CTD PMID:23649840 wortmannin multiple interactions ISO RGD:69423 6480464 Wortmannin inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], Wortmannin inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849 , PMID:25398788 xylose increases expression EXP 6480464 Xylose results in increased expression of SREBF1 mRNA CTD PMID:10913129 Y-27632 multiple interactions ISO RGD:69423 6480464 Y 27632 inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849
