Srebf1 (sterol regulatory element binding transcription factor 1) - Rat Genome Database

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Gene: Srebf1 (sterol regulatory element binding transcription factor 1) Mus musculus
Analyze
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
RGD ID: 69474
MGI Page MGI
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including mRNA transcription by RNA polymerase II; regulation of lipid metabolic process; and regulation of transcription by RNA polymerase II. Localizes to cytoplasm; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in disease of metabolism and type 2 diabetes mellitus. Orthologous to human SREBF1 (sterol regulatory element binding transcription factor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADD-; ADD-1; ADD1; adipocyte determination- and differentiation-dependent factor 1; bHLHd; bHLHd1; D630008H06; SRE; SREB; SREBP; SREBP-1; SREBP-1a; SREBP-1c; SREBP1; SREBP1c; sterol regulatory element binding factor 1; sterol regulatory element-binding protein 1; sterol regulatory element-binding transcription factor 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,089,910 - 60,113,407 (-)NCBIGRCm39mm39
GRCm39 Ensembl1160,089,915 - 60,113,407 (-)Ensembl
GRCm381160,199,084 - 60,224,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,199,089 - 60,222,581 (-)EnsemblGRCm38mm10GRCm38
MGSCv371160,012,591 - 60,034,106 (-)NCBIGRCm37mm9NCBIm37
MGSCv361160,015,284 - 60,036,799 (-)NCBImm8
Celera1166,655,030 - 66,676,425 (+)NCBICelera
Cytogenetic Map11B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-cotinine  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(2,4,5-trichlorophenoxy)acetic acid  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-carnitine  (ISO)
(R)-lipoic acid  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,10-phenanthroline  (ISO)
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose  (EXP)
1,3-dichloropropan-2-ol  (EXP,ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-benzylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose 6-phosphate  (EXP)
2-deoxy-D-glucose  (EXP)
2-naphthylamine  (ISO)
22-Hydroxycholesterol  (EXP,ISO)
25-hydroxycholesterol  (EXP,ISO)
26-hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-phenylprop-2-enal  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
4-tert-Octylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
8-Br-cAMP  (ISO)
9-cis,11-trans-octadecadienoic acid  (EXP)
9-cis-retinoic acid  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
alcohol  (EXP)
aldehydo-D-glucosamine 6-phosphate  (EXP)
aldehydo-D-glucose  (EXP,ISO)
aldrin  (EXP)
all-trans-retinoic acid  (EXP)
alliin  (ISO)
allopurinol  (ISO)
alpha-D-galactose  (EXP)
alpha-linolenic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP,ISO)
amitriptyline  (ISO)
amlexanox  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP,ISO)
atorvastatin calcium  (ISO)
atrazine  (EXP)
Azaspiracid  (ISO)
AZD4547  (ISO)
azoxystrobin  (EXP)
baicalein  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzylpenicillin  (EXP)
berberine  (EXP,ISO)
beta-carotene  (ISO)
beta-D-glucosamine 6-sulfate  (EXP)
beta-hexachlorocyclohexane  (EXP,ISO)
beta-naphthoflavone  (EXP)
betulin  (ISO)
bexarotene  (ISO)
bezafibrate  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
boric acid  (EXP)
bromobenzene  (ISO)
buspirone  (ISO)
buta-1,3-diene  (EXP)
butyric acid  (EXP,ISO)
C60 fullerene  (ISO)
Cacalol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (EXP)
carbendazim  (EXP)
CARBENOXOLONE  (ISO)
carbon nanotube  (EXP,ISO)
carvedilol  (ISO)
cerivastatin  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chitosan  (ISO)
chloroethene  (EXP)
chlorohydrocarbon  (ISO)
cholate  (ISO)
cholesterol  (EXP,ISO)
choline  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
citalopram  (ISO)
clofazimine  (ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clozapine  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (EXP,ISO)
cortisol  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
D-gluconic acid  (ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (EXP)
dabrafenib  (ISO)
DDE  (ISO)
deoxypodophyllotoxin  (EXP,ISO)
depsipeptide  (ISO)
desmosterol  (EXP)
dexamethasone  (EXP,ISO)
Diallyl sulfide  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
diethyl maleate  (ISO)
diethylstilbestrol  (EXP)
dihydroartemisinin  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
elemental selenium  (EXP,ISO)
endosulfan  (ISO)
entinostat  (ISO)
erythromycin A  (EXP)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ezetimibe  (ISO)
fenofibrate  (EXP,ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (EXP,ISO)
fumonisin B1  (EXP)
furan  (ISO)
gadolinium trichloride  (ISO)
galactose  (EXP)
gamma-hexachlorocyclohexane  (ISO)
Gastrodin  (EXP)
gefitinib  (ISO)
genistein  (EXP,ISO)
geraniol  (ISO)
ginsenoside Re  (EXP,ISO)
glucagon  (EXP)
glucose  (EXP,ISO)
glutathione  (EXP)
glycerol 2-phosphate  (ISO)
glyphosate  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
guggulsterone  (EXP,ISO)
GW 3965  (EXP,ISO)
GW 4064  (ISO)
GW 7647  (ISO)
herbacetin  (EXP)
hexadecanoic acid  (EXP,ISO)
Honokiol  (ISO)
hydrazines  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
imipramine  (ISO)
indole-3-methanol  (ISO)
kahweol  (ISO)
ketamine  (ISO)
ketotifen  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP,ISO)
linoleic acid  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP)
losartan  (ISO)
lovastatin  (EXP,ISO)
luteolin  (EXP)
LY294002  (ISO)
magnesium atom  (ISO)
Magnolol  (ISO)
melatonin  (EXP)
metformin  (ISO)
methyl methanesulfonate  (ISO)
mevastatin  (EXP,ISO)
microcystin-LR  (EXP)
miquelianin  (ISO)
mirtazapine  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monocrotophos  (ISO)
monosodium L-glutamate  (EXP,ISO)
myricetin  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-methylformamide  (EXP)
N-methylnicotinate  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
naloxone  (ISO)
naringin  (EXP)
nefazodone  (ISO)
nelfinavir  (ISO)
nevirapine  (ISO)
nicotinamide  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
olanzapine  (EXP)
olaparib  (EXP)
oleanolic acid  (ISO)
oleic acid  (EXP,ISO)
oleuropein  (ISO)
Olmesartan medoxomil  (ISO)
oroxylin A  (EXP,ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
Paxilline  (ISO)
PD 168393  (ISO)
penconazole  (EXP)
perfluorododecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
picolinic acid  (EXP)
pirinixic acid  (EXP,ISO)
platycodin D  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP,ISO)
propamocarb  (EXP)
propiconazole  (EXP,ISO)
puerarin  (EXP)
Pyridostigmine bromide  (EXP)
quercetin  (EXP,ISO)
raffinose  (EXP,ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
risperidone  (EXP)
ritonavir  (EXP)
rotenone  (ISO)
S-allylcysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salubrinal  (ISO)
SB 431542  (ISO)
scopoletin  (ISO)
selenium atom  (EXP,ISO)
selenomethionine  (EXP)
silibinin  (ISO)
simvastatin  (ISO)
sirolimus  (EXP)
sirtinol  (ISO)
sodium arsenite  (EXP,ISO)
sodium cholate  (EXP)
sodium dichromate  (ISO)
starch  (ISO)
stavudine  (ISO)
streptozocin  (EXP,ISO)
sucrose  (EXP,ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
tebuconazole  (ISO)
testosterone  (EXP)
testosterone cypionate  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP,ISO)
tetramethylpyrazine  (EXP)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (ISO)
thymol  (EXP)
thymol sulfate(1-)  (EXP)
topiramate  (ISO)
trametinib  (ISO)
trans-caffeic acid  (ISO)
tributyl phosphate  (ISO)
tributylstannane  (EXP,ISO)
Tributyltin oxide  (EXP,ISO)
triclosan  (ISO)
triolein  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP,ISO)
tyrphostin AG 1478  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vemurafenib  (ISO)
vincristine  (ISO)
wortmannin  (ISO)
xylose  (EXP)
Y-27632  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
cellular response to fatty acid  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to starvation  (IDA,ISO)
cholesterol metabolic process  (ISO)
circadian rhythm  (IEP)
fat cell differentiation  (IMP)
insulin receptor signaling pathway  (IDA)
lipid biosynthetic process  (IDA)
lipid localization  (ISO)
lipid metabolic process  (IEA)
lung development  (ISO)
mRNA transcription by RNA polymerase II  (IDA)
negative regulation of insulin secretion  (IMP)
negative regulation of transcription by RNA polymerase II  (IDA,IGI)
positive regulation of cholesterol biosynthetic process  (IDA,IMP,ISO)
positive regulation of fatty acid biosynthetic process  (TAS)
positive regulation of histone deacetylation  (IDA)
positive regulation of innate immune response  (IMP)
positive regulation of lipid biosynthetic process  (IMP)
positive regulation of pri-miRNA transcription by RNA polymerase II  (IDA,ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
positive regulation of transcription, DNA-templated  (IDA,ISO)
positive regulation of triglyceride biosynthetic process  (IDA,IMP)
regulation of autophagy of mitochondrion  (ISO)
regulation of fatty acid metabolic process  (IMP)
regulation of heart rate by chemical signal  (IMP)
regulation of insulin secretion  (IMP)
regulation of lipid storage  (ISO)
regulation of protein stability  (ISO)
regulation of protein targeting to mitochondrion  (ISO)
regulation of transcription by RNA polymerase II  (IBA,IDA,IMP,ISO)
regulation of transcription, DNA-templated  (IDA)
response to cAMP  (ISO)
response to drug  (ISO)
response to ethanol  (ISO)
response to fatty acid  (ISO)
response to food  (ISO)
response to glucagon  (ISO)
response to glucose  (IMP)
response to lipid  (ISO)
response to organic cyclic compound  (ISO)
response to peptide hormone  (ISO)
response to progesterone  (ISO)
response to retinoic acid  (ISO)
SREBP signaling pathway  (ISO)
steroid metabolic process  (IEA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Cho EJ, etal., J Pharm Pharmacol. 2007 May;59(5):687-94.
2. Desai M, etal., Reprod Sci. 2008 Oct;15(8):785-96.
3. Hu YB, etal., Drug Des Devel Ther. 2018 Jul 16;12:2213-2221. doi: 10.2147/DDDT.S170518. eCollection 2018.
4. Ishigaki N, etal., Biochem Biophys Res Commun. 2007 Dec 21;364(3):502-8. Epub 2007 Oct 16.
5. Jiang T, etal., J Am Soc Nephrol. 2005 Aug;16(8):2385-94. Epub 2005 Jun 8.
6. Jun H, etal., Histochem Cell Biol. 2009 Mar;131(3):327-45. Epub 2008 Dec 2.
7. Kim JM, etal., Exp Mol Med. 2006 Aug 31;38(4):385-92.
8. Li Y, etal., Diabetes Metab Res Rev. 2008 Sep;24(6):498-506.
9. Liu JX, etal., Diabetes Res Clin Pract. 2008 Oct;82(1):42-7. Epub 2008 Aug 8.
10. MGD and Homologene mouse data transfer
11. MGD data from the GO Consortium
12. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. Osborne TF and Espenshade PJ, Genes Dev. 2009 Nov 15;23(22):2578-91.
14. Ota T, etal., Gastroenterology. 2007 Jan;132(1):282-93. Epub 2006 Oct 12.
15. Pallottini V, etal., J Cell Biochem. 2006 Aug 1;98(5):1044-53.
16. Park HJ, etal., Circ Res. 2009 May 7.
17. Pipeline to import KEGG annotations from KEGG into RGD
18. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
19. Proctor G, etal., Diabetes. 2006 Sep;55(9):2502-9.
20. RGD automated import pipeline
21. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. RGD automated import pipeline for gene-chemical interactions
23. Sajan MP, etal., Diabetologia. 2009 Jun;52(6):1197-207. Epub 2009 Apr 9.
24. Wang Z, etal., Diabetes. 2005 Aug;54(8):2328-35.
25. Wu J, etal., Am J Physiol. 1999 Dec;277(6 Pt 1):E1087-94.
26. Xu W, etal., Toxicol Appl Pharmacol. 2017 Jan 15;315:23-34. doi: 10.1016/j.taap.2016.12.001. Epub 2016 Dec 6.
Additional References at PubMed
PMID:8827514   PMID:8833906   PMID:8889548   PMID:9062340   PMID:9062341   PMID:9329978   PMID:9337407   PMID:9890958   PMID:10049592   PMID:10052151   PMID:10064584   PMID:10349636  
PMID:10514488   PMID:10585467   PMID:10585468   PMID:10588675   PMID:10922068   PMID:10949029   PMID:10982846   PMID:11042159   PMID:11076861   PMID:11090130   PMID:11208732   PMID:11217851  
PMID:11309661   PMID:11394880   PMID:11739104   PMID:11781189   PMID:11782483   PMID:11792729   PMID:11829742   PMID:11875060   PMID:11923308   PMID:11929849   PMID:12032166   PMID:12036955  
PMID:12048207   PMID:12086931   PMID:12163031   PMID:12242332   PMID:12477932   PMID:12520002   PMID:12576519   PMID:12736163   PMID:12855691   PMID:12897148   PMID:12897158   PMID:12904583  
PMID:12975478   PMID:14512514   PMID:14522948   PMID:14633850   PMID:14654692   PMID:14662765   PMID:14668345   PMID:14681479   PMID:14722127   PMID:14755333   PMID:14985341   PMID:14985368  
PMID:14988238   PMID:15037635   PMID:15062879   PMID:15066988   PMID:15123650   PMID:15123654   PMID:15187085   PMID:15462672   PMID:15509573   PMID:15589694   PMID:15618518   PMID:15627654  
PMID:15637161   PMID:15680331   PMID:15782199   PMID:15851526   PMID:15855315   PMID:15896329   PMID:16046411   PMID:16054068   PMID:16054077   PMID:16100574   PMID:16106047   PMID:16141072  
PMID:16141073   PMID:16249184   PMID:16316337   PMID:16407292   PMID:16498401   PMID:16644917   PMID:16794015   PMID:16804073   PMID:16879892   PMID:16890542   PMID:16943421   PMID:17074803  
PMID:17107947   PMID:17188681   PMID:17273973   PMID:17290224   PMID:17296605   PMID:17439953   PMID:17456898   PMID:17484888   PMID:17636037   PMID:17651982   PMID:17662109   PMID:17666524  
PMID:17880923   PMID:17890326   PMID:17919187   PMID:17921436   PMID:17967808   PMID:18060044   PMID:18086558   PMID:18178930   PMID:18202130   PMID:18226595   PMID:18287559   PMID:18347010  
PMID:18395093   PMID:18395094   PMID:18413311   PMID:18458149   PMID:18557763   PMID:18627005   PMID:18669923   PMID:18682402   PMID:18769020   PMID:18782084   PMID:18791464   PMID:18799693  
PMID:18838740   PMID:19056350   PMID:19110480   PMID:19155087   PMID:19244231   PMID:19254698   PMID:19403048   PMID:19459730   PMID:19564420   PMID:19605464   PMID:19633360   PMID:19666523  
PMID:19682428   PMID:19721697   PMID:19741146   PMID:19786558   PMID:19808675   PMID:19811452   PMID:19874695   PMID:19915177   PMID:20005944   PMID:20032468   PMID:20037162   PMID:20059953  
PMID:20145241   PMID:20179320   PMID:20211142   PMID:20385813   PMID:20412781   PMID:20554776   PMID:20575761   PMID:20595232   PMID:20670887   PMID:20686481   PMID:20720008   PMID:20739508  
PMID:20817729   PMID:20847591   PMID:20863500   PMID:20943752   PMID:21093473   PMID:21145868   PMID:21245029   PMID:21267068   PMID:21357625   PMID:21440680   PMID:21459323   PMID:21531336  
PMID:21540177   PMID:21546605   PMID:21549685   PMID:21757781   PMID:21816276   PMID:21871872   PMID:21873635   PMID:21911492   PMID:21953514   PMID:22031849   PMID:22035958   PMID:22090424  
PMID:22318315   PMID:22331133   PMID:22355693   PMID:22361881   PMID:22384276   PMID:22415588   PMID:22493063   PMID:22511764   PMID:22521878   PMID:22710480   PMID:22872236   PMID:22984430  
PMID:22988430   PMID:23000402   PMID:23126661   PMID:23347184   PMID:23348573   PMID:23419397   PMID:23542164   PMID:23563690   PMID:23637738   PMID:23727646   PMID:23734208   PMID:23774190  
PMID:23823476   PMID:23850470   PMID:23891753   PMID:23924694   PMID:23945440   PMID:23981283   PMID:23999723   PMID:24300912   PMID:24379443   PMID:24398675   PMID:24425205   PMID:24603613  
PMID:24606891   PMID:24606892   PMID:24847504   PMID:24931346   PMID:24993831   PMID:25013763   PMID:25016220   PMID:25249504   PMID:25348957   PMID:25398788   PMID:25533663   PMID:25817536  
PMID:25971371   PMID:26147081   PMID:26220403   PMID:26271478   PMID:26282207   PMID:26332085   PMID:26388522   PMID:26508642   PMID:26510459   PMID:26555260   PMID:26685326   PMID:26721591  
PMID:26835538   PMID:26851362   PMID:26873854   PMID:26935028   PMID:26973245   PMID:27008858   PMID:27125672   PMID:27166182   PMID:27252523   PMID:27307439   PMID:27382175   PMID:27412556  
PMID:27452504   PMID:27477273   PMID:27524233   PMID:27545894   PMID:27627966   PMID:27659424   PMID:27679530   PMID:27689697   PMID:27826032   PMID:27866836   PMID:27888103   PMID:27901044  
PMID:27930960   PMID:27958883   PMID:27974211   PMID:28027595   PMID:28041958   PMID:28244871   PMID:28256090   PMID:28270440   PMID:28364022   PMID:28449683   PMID:28467654   PMID:28701079  
PMID:28796629   PMID:28827316   PMID:28855656   PMID:29113994   PMID:29244870   PMID:29269047   PMID:29315766   PMID:29335275   PMID:29352167   PMID:29356058   PMID:29385670   PMID:29472293  
PMID:29555473   PMID:29587401   PMID:29618580   PMID:29668871   PMID:29679236   PMID:29723221   PMID:29857051   PMID:29950673   PMID:29952285   PMID:30074985   PMID:30154417   PMID:30181160  
PMID:30352876   PMID:30354203   PMID:30356113   PMID:30430717   PMID:30530672   PMID:30700132   PMID:30821074   PMID:30935969   PMID:31144451   PMID:31270208   PMID:31451658   PMID:31479733  
PMID:31875875   PMID:31998789   PMID:32301540   PMID:32516576   PMID:32595040   PMID:33003626   PMID:33591268  


Genomics

Comparative Map Data
Srebf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,089,910 - 60,113,407 (-)NCBIGRCm39mm39
GRCm39 Ensembl1160,089,915 - 60,113,407 (-)Ensembl
GRCm381160,199,084 - 60,224,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,199,089 - 60,222,581 (-)EnsemblGRCm38mm10GRCm38
MGSCv371160,012,591 - 60,034,106 (-)NCBIGRCm37mm9NCBIm37
MGSCv361160,015,284 - 60,036,799 (-)NCBImm8
Celera1166,655,030 - 66,676,425 (+)NCBICelera
Cytogenetic Map11B2NCBI
SREBF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1717,810,399 - 17,837,011 (-)EnsemblGRCh38hg38GRCh38
GRCh381717,811,334 - 17,837,017 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371717,714,648 - 17,740,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,656,111 - 17,681,050 (-)NCBINCBI36hg18NCBI36
Build 341717,656,110 - 17,681,050NCBI
Celera1718,654,135 - 18,680,982 (-)NCBI
Cytogenetic Map17p11.2NCBI
HuRef1717,466,908 - 17,494,061 (-)NCBIHuRef
CHM1_11717,723,458 - 17,749,109 (-)NCBICHM1_1
Srebf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21045,007,637 - 45,029,650 (-)NCBI
Rnor_6.0 Ensembl1046,570,996 - 46,593,009 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01046,570,996 - 46,593,021 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01046,326,015 - 46,348,035 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,461,684 - 46,483,646 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1044,264,866 - 44,286,830 (-)NCBICelera
Cytogenetic Map10q22NCBI
Srebf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955577171,425 - 186,046 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955577171,425 - 183,669 (+)NCBIChiLan1.0ChiLan1.0
SREBF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11738,405,794 - 38,432,045 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1738,405,794 - 38,432,045 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01733,458,196 - 33,484,643 (+)NCBIMhudiblu_PPA_v0panPan3
SREBF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,663,809 - 41,686,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,663,773 - 41,686,776 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha541,802,335 - 41,825,236 (+)NCBI
ROS_Cfam_1.0541,769,693 - 41,792,654 (+)NCBI
UMICH_Zoey_3.1541,737,352 - 41,760,245 (+)NCBI
UNSW_CanFamBas_1.0541,684,736 - 41,707,631 (+)NCBI
UU_Cfam_GSD_1.0541,876,687 - 41,899,587 (+)NCBI
Srebf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,447,521 - 61,458,579 (+)NCBI
SpeTri2.0NW_0049367411,408,669 - 1,419,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SREBF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,733,907 - 60,751,265 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,733,967 - 60,750,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SREBF1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11616,847,603 - 16,874,239 (-)NCBI
ChlSab1.1 Ensembl1616,845,491 - 16,859,554 (-)Ensembl
Srebf1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248493,602,103 - 3,623,922 (+)NCBI

Position Markers
RH132247  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381160,199,212 - 60,199,409UniSTSGRCm38
MGSCv371160,012,714 - 60,012,911UniSTSGRCm37
Celera1166,676,105 - 66,676,302UniSTS
Cytogenetic Map11B2UniSTS
Srebf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B2UniSTS
cM Map11 UniSTS
PMC134715P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381160,206,002 - 60,206,081UniSTSGRCm38
MGSCv371160,019,504 - 60,019,583UniSTSGRCm37
Celera1166,669,572 - 66,669,651UniSTS
Cytogenetic Map11B2UniSTS
PMC164762P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381160,210,509 - 60,210,829UniSTSGRCm38
MGSCv371160,024,011 - 60,024,331UniSTSGRCm37
Celera1166,664,825 - 66,665,145UniSTS
Cytogenetic Map11B2UniSTS
PMC166346P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381160,210,543 - 60,210,766UniSTSGRCm38
MGSCv371160,024,045 - 60,024,268UniSTSGRCm37
Celera1166,664,888 - 66,665,111UniSTS
Cytogenetic Map11B2UniSTS
GDB:592807  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Celera1166,674,846 - 66,675,044UniSTS
Cytogenetic Map11B2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2495
Count of miRNA genes:715
Interacting mature miRNAs:954
Transcripts:ENSMUST00000020846, ENSMUST00000129869, ENSMUST00000134660, ENSMUST00000136215, ENSMUST00000136426, ENSMUST00000141161, ENSMUST00000144942, ENSMUST00000147967, ENSMUST00000149238, ENSMUST00000154620, ENSMUST00000154925, ENSMUST00000156304
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001313979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB046200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB072350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF374266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY965048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY288773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020846   ⟹   ENSMUSP00000020846
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,199,089 - 60,220,604 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129869
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,201,364 - 60,202,215 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134660   ⟹   ENSMUSP00000122934
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,199,089 - 60,207,188 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136215
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,206,950 - 60,222,581 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136426
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,202,659 - 60,203,488 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141161
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,200,130 - 60,201,040 (-)Ensembl
RefSeq Acc Id: ENSMUST00000144942   ⟹   ENSMUSP00000120777
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,200,463 - 60,210,465 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147967
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,205,959 - 60,210,392 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149238
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,203,101 - 60,204,290 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154620
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,204,189 - 60,206,112 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154925
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,201,801 - 60,203,857 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156304
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,201,366 - 60,202,624 (-)Ensembl
RefSeq Acc Id: NM_001313979   ⟹   NP_001300908
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,910 - 60,111,453 (-)NCBI
GRCm381160,199,084 - 60,220,627 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001358314   ⟹   NP_001345243
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,910 - 60,101,297 (-)NCBI
GRCm381160,199,084 - 60,210,471 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001358315   ⟹   NP_001345244
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,910 - 60,113,407 (-)NCBI
GRCm381160,199,084 - 60,222,581 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011480   ⟹   NP_035610
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,910 - 60,111,453 (-)NCBI
GRCm381160,199,084 - 60,220,627 (-)NCBI
MGSCv371160,012,591 - 60,034,106 (-)RGD
Celera1166,655,030 - 66,676,425 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532716   ⟹   XP_006532779
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,920 - 60,101,315 (-)NCBI
GRCm381160,199,094 - 60,210,485 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245748   ⟹   XP_030101608
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,920 - 60,100,086 (-)NCBI
GRCm381160,199,094 - 60,209,260 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156490   ⟹   XP_036012383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,920 - 60,100,164 (-)NCBI
RefSeq Acc Id: XM_036156491   ⟹   XP_036012384
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,089,920 - 60,098,414 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_035610   ⟸   NM_011480
- Peptide Label: isoform a precursor
- UniProtKB: Q9WTN3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532779   ⟸   XM_006532716
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001300908   ⟸   NM_001313979
- Peptide Label: isoform b
- UniProtKB: Q9WTN3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001345244   ⟸   NM_001358315
- Peptide Label: isoform d
RefSeq Acc Id: NP_001345243   ⟸   NM_001358314
- Peptide Label: isoform c
RefSeq Acc Id: XP_030101608   ⟸   XM_030245748
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000120777   ⟸   ENSMUST00000144942
RefSeq Acc Id: ENSMUSP00000020846   ⟸   ENSMUST00000020846
RefSeq Acc Id: ENSMUSP00000122934   ⟸   ENSMUST00000134660
RefSeq Acc Id: XP_036012383   ⟸   XM_036156490
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036012384   ⟸   XM_036156491
- Peptide Label: isoform X2
Protein Domains
bHLH

Promoters
RGD ID:6822227
Promoter ID:MM_KWN:7688
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000012902
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,014,096 - 60,015,542 (-)MPROMDB
RGD ID:6822225
Promoter ID:MM_KWN:7689
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000012869,   OTTMUST00000012900
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,015,681 - 60,016,762 (-)MPROMDB
RGD ID:6822221
Promoter ID:MM_KWN:7690
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000012866,   OTTMUST00000012867,   OTTMUST00000012868
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,016,891 - 60,017,982 (-)MPROMDB
RGD ID:6822224
Promoter ID:MM_KWN:7691
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000012875
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,019,191 - 60,020,067 (-)MPROMDB
RGD ID:6822222
Promoter ID:MM_KWN:7692
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   BoneMarrow_2Hour,   Liver,   Lung
Transcripts:OTTMUST00000012871
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,020,481 - 60,021,412 (-)MPROMDB
RGD ID:6822219
Promoter ID:MM_KWN:7693
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000064158,   OTTMUST00000012872,   OTTMUST00000012874
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,023,741 - 60,024,867 (-)MPROMDB
RGD ID:6822220
Promoter ID:MM_KWN:7694
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000108737,   NM_011480,   UC007JFO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,033,716 - 60,034,302 (-)MPROMDB
RGD ID:6822223
Promoter ID:MM_KWN:7695
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000012873
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,036,186 - 60,036,686 (-)MPROMDB
RGD ID:8674868
Promoter ID:EPDNEW_M15465
Type:initiation region
Name:Srebf1_1
Description:Mus musculus sterol regulatory element binding transcriptionfactor 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381160,220,594 - 60,220,654EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107606 AgrOrtholog
Ensembl Genes ENSMUSG00000020538 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020846 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000120777 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000122934 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020846 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000134660 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000144942 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20787 UniProtKB/Swiss-Prot
MGD MGI:107606 ENTREZGENE
NCBI Gene 20787 ENTREZGENE
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Srebf1 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MQK3_MOUSE UniProtKB/TrEMBL
  F6XZS9_MOUSE UniProtKB/TrEMBL
  Q3TYX1_MOUSE UniProtKB/TrEMBL
  Q9WTN3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3U458 UniProtKB/Swiss-Prot
  Q3UDJ3 UniProtKB/Swiss-Prot
  Q5SRX5 UniProtKB/Swiss-Prot
  Q8C733 UniProtKB/Swiss-Prot
  Q99JK7 UniProtKB/Swiss-Prot