(+)-dexrazoxane multiple interactions EXP 6480464 [Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP12 mRNA CTD PMID:26873546 (+)-pilocarpine multiple interactions ISO RGD:621758 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 (+)-Tetrandrine increases cleavage ISO RGD:1348077 6480464 tetrandrine results in increased cleavage of CASP12 protein CTD PMID:26822499 (R)-noradrenaline multiple interactions ISO RGD:621758 6480464 CAT protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP12 protein alternative form] CTD PMID:16338971 (R)-noradrenaline increases cleavage ISO RGD:621758 6480464 Norepinephrine results in increased cleavage of CASP12 protein alternative form CTD PMID:16338971 (S)-nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 (S)-nicotine multiple interactions ISO RGD:621758 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:621758 6480464 2 more ... CTD PMID:19414516 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:621758 6480464 o, p'-DDT results in increased expression of CASP12 mRNA CTD PMID:22937105 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of CASP12 mRNA CTD PMID:26682919 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene increases expression ISO RGD:621758 6480464 Mitotane analog results in increased expression of CASP12 mRNA, Mitotane results in increased expression of CASP12 mRNA CTD PMID:23485034 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1348077 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases cleavage EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-naphthyl isothiocyanate increases expression ISO RGD:621758 6480464 1-Naphthylisothiocyanate results in increased expression of CASP12 mRNA CTD PMID:25380136 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:621758 6480464 2 more ... CTD PMID:19576244 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:621758 6480464 2 more ... CTD PMID:19576244 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:621758 6480464 2 more ... CTD PMID:19576244 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:621758 6480464 2 more ... CTD PMID:19576244 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CASP12 mRNA CTD PMID:21570461 2,4,6-trinitrobenzenesulfonic acid increases cleavage ISO RGD:621758 6480464 Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein CTD PMID:30503585 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:621758 6480464 Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form], Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 2,4-dinitrotoluene affects expression ISO RGD:621758 6480464 2, 4-dinitrotoluene affects the expression of CASP12 mRNA CTD PMID:21346803 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 2-aminoethoxydiphenylborane multiple interactions ISO RGD:621758 6480464 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of CASP12 mRNA CTD PMID:25172293 4,4'-diaminodiphenylmethane increases expression ISO RGD:621758 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CASP12 mRNA CTD PMID:25380136 4-aminophenol multiple interactions ISO RGD:621758 6480464 4-aminophenol results in increased activity of and results in increased cleavage of CASP12 protein more ... CTD PMID:17567590 , PMID:17567592 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [arsenic trioxide results in increased expression of CASP12 protein modified form] more ... CTD PMID:17459145 more ... 4-phenylbutyric acid multiple interactions ISO RGD:1348077 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein] CTD PMID:28245985 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of CASP12 mRNA CTD PMID:21319176 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CASP12 mRNA CTD PMID:30807115 aflatoxin B1 decreases methylation ISO RGD:1348077 6480464 Aflatoxin B1 results in decreased methylation of CASP12 gene CTD PMID:27153756 aldehydo-D-glucose increases cleavage EXP 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 aldehydo-D-glucose multiple interactions EXP 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 all-trans-retinoic acid multiple interactions ISO RGD:1348077 6480464 [Tretinoin co-treated with Paclitaxel] results in increased expression of CASP12 protein CTD PMID:17701358 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CASP12 mRNA CTD PMID:22498432 alpha-naphthoflavone increases cleavage EXP 6480464 alpha-naphthoflavone results in increased cleavage of CASP12 protein CTD PMID:30508555 aluminium atom multiple interactions EXP 6480464 [aluminum chloride results in increased abundance of Aluminum] which results in increased expression of CASP12 mRNA CTD PMID:29635646 aluminium(0) multiple interactions EXP 6480464 [aluminum chloride results in increased abundance of Aluminum] which results in increased expression of CASP12 mRNA CTD PMID:29635646 aluminium(3+) multiple interactions EXP 6480464 [aluminum chloride results in increased abundance of Aluminum] which results in increased expression of CASP12 mRNA CTD PMID:29635646 ammonium chloride affects expression ISO RGD:621758 6480464 Ammonium Chloride affects the expression of CASP12 mRNA CTD PMID:16483693 ammonium chloride increases expression ISO RGD:621758 6480464 Ammonium Chloride results in increased expression of CASP12 protein CTD PMID:16483693 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:621758 6480464 pyrazolanthrone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein], Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein] CTD PMID:20493918 arsenic acid increases activity ISO RGD:621758 6480464 arsenic acid results in increased activity of CASP12 protein CTD PMID:18226606 arsenite(3-) multiple interactions ISO RGD:621758 6480464 Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein] more ... CTD PMID:18077580 , PMID:18226606 arsenite(3-) increases expression ISO RGD:1348077 6480464 arsenite results in increased expression of CASP12 protein CTD PMID:26677073 arsenite(3-) increases activity ISO RGD:621758 6480464 arsenite results in increased activity of CASP12 protein CTD PMID:18077580 , PMID:18226606 BAPTA increases expression ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 BAPTA multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 benzo[e]pyrene increases activity ISO RGD:621758 6480464 benzo(e)pyrene results in increased activity of CASP12 protein CTD PMID:19899995 benzo[e]pyrene increases activity ISO RGD:1348077 6480464 benzo(e)pyrene results in increased activity of CASP12 protein CTD PMID:18586875 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CASP12 mRNA CTD PMID:20807545 bisphenol A increases expression ISO RGD:621758 6480464 bisphenol A results in increased expression of CASP12 mRNA CTD PMID:25181051 bortezomib increases cleavage EXP 6480464 Bortezomib results in increased cleavage of CASP12 protein CTD PMID:15509775 , PMID:16357177 brefeldin A increases activity EXP 6480464 Brefeldin A results in increased activity of CASP12 protein CTD PMID:20493918 brefeldin A multiple interactions EXP 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein] CTD PMID:20493918 cadmium atom multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:19442655 cadmium atom increases activity EXP 6480464 Cadmium results in increased activity of CASP12 protein CTD PMID:20600546 cadmium dichloride increases activity EXP 6480464 Cadmium Chloride results in increased activity of CASP12 protein CTD PMID:17588656 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CASP12 mRNA CTD PMID:25409916 Chikusetsusaponin-V multiple interactions ISO RGD:1348077 6480464 chikusetsusaponin V inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA] CTD PMID:25073091 chloroacetic acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein] more ... CTD PMID:25451595 chloroquine multiple interactions ISO RGD:621758 6480464 Chloroquine promotes the reaction [cadmium acetate results in increased expression of CASP12 protein] CTD PMID:29870746 chlorpyrifos affects expression ISO RGD:621758 6480464 Chlorpyrifos affects the expression of CASP12 mRNA CTD PMID:17452286 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA CTD PMID:20938992 cimetidine multiple interactions EXP 6480464 Cimetidine inhibits the reaction [Ethanol results in increased expression of CASP12 protein] CTD PMID:27983966 cisplatin multiple interactions ISO RGD:1348077 6480464 [vorinostat co-treated with Cisplatin] results in increased activity of CASP12 protein CTD PMID:19280190 cisplatin increases expression ISO RGD:621758 6480464 Cisplatin results in increased expression of CASP12 mRNA, Cisplatin results in increased expression of CASP12 protein CTD PMID:23603837 cisplatin multiple interactions ISO RGD:621758 6480464 Cisplatin results in increased cleavage of and results in increased activity of CASP12 protein more ... CTD PMID:17567590 , PMID:23603837 cisplatin affects cleavage ISO RGD:621758 6480464 Cisplatin affects the cleavage of CASP12 protein CTD PMID:20071420 cisplatin increases cleavage EXP 6480464 Cisplatin results in increased cleavage of CASP12 protein CTD PMID:16357177 , PMID:21616140 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in decreased expression of CASP12 mRNA more ... CTD PMID:21616140 , PMID:23625948 citric acid multiple interactions ISO RGD:1348077 6480464 [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 clofibric acid multiple interactions ISO RGD:621758 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CASP12 mRNA CTD PMID:17602206 cobalt dichloride decreases expression ISO RGD:621758 6480464 cobaltous chloride results in decreased expression of CASP12 mRNA CTD PMID:24386269 corticosterone decreases expression ISO RGD:621758 6480464 Corticosterone results in decreased expression of CASP12 mRNA CTD PMID:15755911 curcumin increases expression EXP 6480464 Curcumin results in increased expression of CASP12 protein CTD PMID:21793155 curcumin multiple interactions ISO RGD:621758 6480464 Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:25541178 D-glucose increases cleavage EXP 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 D-glucose multiple interactions EXP 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 DDE increases expression ISO RGD:621758 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CASP12 mRNA CTD PMID:21384494 demethoxycurcumin multiple interactions ISO RGD:1348077 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form] CTD PMID:26264395 desferrioxamine B multiple interactions ISO RGD:1348077 6480464 Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:23764342 diazinon affects expression ISO RGD:621758 6480464 Diazinon affects the expression of CASP12 mRNA CTD PMID:17452286 dieldrin affects expression ISO RGD:621758 6480464 Dieldrin affects the expression of CASP12 mRNA CTD PMID:22546817 diethylstilbestrol increases activity ISO RGD:621758 6480464 Diethylstilbestrol results in increased activity of CASP12 protein CTD PMID:20932895 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of CASP12 mRNA, Cacodylic Acid results in increased expression of CASP12 protein CTD PMID:22246474 dioxygen increases cleavage EXP 6480464 Oxygen deficiency results in increased cleavage of CASP12 protein CTD PMID:24680926 doxorubicin multiple interactions ISO RGD:621758 6480464 Doxorubicin results in increased cleavage of and results in increased activity of CASP12 protein, pifithrin inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:15556633 , PMID:16687611 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CASP12 mRNA CTD PMID:26873546 doxorubicin multiple interactions EXP 6480464 [Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP12 mRNA CTD PMID:26873546 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of CASP12 protein CTD PMID:20656019 edaravone multiple interactions ISO RGD:621758 6480464 Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein] CTD PMID:21429313 emodin decreases expression EXP 6480464 Emodin results in decreased expression of CASP12 mRNA CTD PMID:21319176 endosulfan decreases expression ISO RGD:621758 6480464 Endosulfan results in decreased expression of CASP12 mRNA CTD PMID:29391264 ethanol increases cleavage EXP 6480464 Ethanol results in increased cleavage of CASP12 protein CTD PMID:28119953 ethanol multiple interactions EXP 6480464 Cimetidine inhibits the reaction [Ethanol results in increased expression of CASP12 protein] more ... CTD PMID:27983966 , PMID:28119953 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CASP12 protein CTD PMID:27983966 ethanol increases activity ISO RGD:1348077 6480464 Ethanol results in increased activity of CASP12 protein CTD PMID:24224909 ethanol multiple interactions ISO RGD:1348077 6480464 resveratrol inhibits the reaction [Ethanol results in increased activity of CASP12 protein], resveratrol inhibits the reaction [Ethanol results in increased expression of CASP12 protein modified form] CTD PMID:24224909 ethanol increases expression ISO RGD:1348077 6480464 Ethanol results in increased expression of CASP12 protein modified form CTD PMID:24224909 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 excitatory amino acid agonist multiple interactions EXP 6480464 Excitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein, Plant Extracts inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein] CTD PMID:28315776 fisetin increases expression ISO RGD:1348077 6480464 fisetin results in increased expression of CASP12 protein CTD PMID:28181380 fisetin multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 flutamide decreases expression ISO RGD:621758 6480464 Flutamide results in decreased expression of CASP12 mRNA CTD PMID:24793618 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA, Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP12 protein modified form] CTD PMID:20938992 , PMID:29068127 furan increases expression ISO RGD:621758 6480464 furan results in increased expression of CASP12 mRNA CTD PMID:22079235 furosemide affects expression ISO RGD:621758 6480464 Furosemide affects the expression of CASP12 mRNA CTD PMID:17497460 geneticin increases cleavage ISO RGD:1348077 6480464 antibiotic G 418 results in increased cleavage of CASP12 protein CTD PMID:15241557 gentamycin multiple interactions ISO RGD:621758 6480464 Gentamicins results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:17567590 glucose increases cleavage EXP 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 glucose multiple interactions EXP 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 GW 4064 decreases expression EXP 6480464 GW 4064 results in decreased expression of CASP12 mRNA CTD PMID:26655953 heparin multiple interactions EXP 6480464 Heparin inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 hydralazine multiple interactions EXP 6480464 Hydralazine inhibits the reaction [Ethanol results in increased cleavage of CASP12 protein] CTD PMID:28119953 hydrogen peroxide increases expression ISO RGD:621758 6480464 Hydrogen Peroxide results in increased expression of CASP12 protein modified form CTD PMID:22081883 hydrogen peroxide increases activity ISO RGD:621758 6480464 Hydrogen Peroxide results in increased activity of CASP12 protein CTD PMID:25065601 hydrogen peroxide increases cleavage EXP 6480464 Hydrogen Peroxide results in increased cleavage of CASP12 protein CTD PMID:20878536 hydrogen peroxide multiple interactions ISO RGD:621758 6480464 calycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased expression of CASP12 protein modified form], PBK protein inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP12 protein] CTD PMID:22081883 , PMID:25065601 hydroxamic acid multiple interactions ISO RGD:621758 6480464 Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form] CTD PMID:30503585 icosanoid multiple interactions ISO RGD:621758 6480464 Eicosanoids analog inhibits the reaction [Cisplatin results in increased expression of CASP12 mRNA], Eicosanoids analog inhibits the reaction [Cisplatin results in increased expression of CASP12 protein] CTD PMID:23603837 iron(III) nitrilotriacetate increases expression ISO RGD:621758 6480464 ferric nitrilotriacetate results in increased expression of CASP12 mRNA CTD PMID:23208426 isoflurane decreases expression ISO RGD:621758 6480464 Isoflurane results in decreased expression of CASP12 mRNA CTD PMID:16978161 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of CASP12 mRNA CTD PMID:25808816 KN-93 multiple interactions ISO RGD:621758 6480464 KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA CTD PMID:20938992 lead(0) increases expression ISO RGD:621758 6480464 Lead results in increased expression of CASP12 mRNA CTD PMID:24791885 lead(2+) increases expression ISO RGD:621758 6480464 Lead results in increased expression of CASP12 mRNA CTD PMID:24791885 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of CASP12 protein CTD PMID:28245985 lipopolysaccharide multiple interactions ISO RGD:1348077 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein] CTD PMID:28245985 lipopolysaccharide increases expression ISO RGD:1348077 6480464 Lipopolysaccharides results in increased expression of CASP12 protein CTD PMID:28245985 lipopolysaccharide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein] CTD PMID:28245985 lithium atom multiple interactions ISO RGD:621758 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 lithium hydride multiple interactions ISO RGD:621758 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 lithium(1+) multiple interactions ISO RGD:621758 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 manganese(II) chloride increases cleavage EXP 6480464 manganese chloride results in increased cleavage of CASP12 protein CTD PMID:26064043 manganese(II) chloride multiple interactions ISO RGD:621758 6480464 SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein] CTD PMID:23934647 manganese(II) chloride increases cleavage ISO RGD:621758 6480464 manganese chloride results in increased cleavage of CASP12 protein CTD PMID:25732873 manganese(II) chloride increases expression ISO RGD:621758 6480464 manganese chloride results in increased expression of CASP12 mRNA, manganese chloride results in increased expression of CASP12 protein CTD PMID:23934647 more ... manganese(II) chloride multiple interactions ISO RGD:1348077 6480464 Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein], manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:23764342 manganese(II) chloride multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein] CTD PMID:26064043 meglumine amidotrizoate increases cleavage ISO RGD:621758 6480464 Diatrizoate Meglumine results in increased cleavage of CASP12 protein CTD PMID:20071420 melatonin multiple interactions ISO RGD:621758 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein] more ... CTD PMID:17645694 more ... methamphetamine increases expression ISO RGD:621758 6480464 Methamphetamine results in increased expression of CASP12 mRNA, Methamphetamine results in increased expression of CASP12 protein CTD PMID:28619521 , PMID:29705343 methamphetamine multiple interactions ISO RGD:1348077 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein] CTD PMID:29705343 methamphetamine increases expression ISO RGD:1348077 6480464 Methamphetamine results in increased expression of CASP12 protein CTD PMID:29705343 methamphetamine increases cleavage ISO RGD:621758 6480464 Methamphetamine results in increased cleavage of CASP12 protein CTD PMID:28070110 methamphetamine multiple interactions ISO RGD:621758 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein], Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein] CTD PMID:28070110 , PMID:29705343 methapyrilene increases expression ISO RGD:621758 6480464 Methapyrilene results in increased expression of CASP12 mRNA CTD PMID:17450226 methylseleninic acid multiple interactions ISO RGD:1348077 6480464 HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein] CTD PMID:16204082 methylseleninic acid increases cleavage ISO RGD:1348077 6480464 methylselenic acid results in increased cleavage of CASP12 protein CTD PMID:16204082 minocycline multiple interactions ISO RGD:621758 6480464 Minocycline inhibits the reaction [APP protein alternative form results in increased activity of CASP12 protein], Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein] CTD PMID:17406652 , PMID:22245251 minocycline decreases expression ISO RGD:621758 6480464 Minocycline results in decreased expression of CASP12 mRNA, Minocycline results in decreased expression of CASP12 protein CTD PMID:14998631 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein], Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] CTD PMID:21616140 , PMID:25451595 N-acetyl-L-cysteine multiple interactions ISO RGD:621758 6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein] more ... CTD PMID:18077580 more ... N-methyl-4-phenylpyridinium increases expression ISO RGD:1348077 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA CTD PMID:25073091 N-methyl-4-phenylpyridinium increases expression ISO RGD:621758 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA CTD PMID:28801915 N-methyl-4-phenylpyridinium increases methylation ISO RGD:621758 6480464 1-Methyl-4-phenylpyridinium results in increased methylation of CASP12 gene CTD PMID:28801915 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:621758 6480464 pyrazolanthrone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein], TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 N-methyl-4-phenylpyridinium increases cleavage ISO RGD:621758 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein CTD PMID:24140863 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:1348077 6480464 chikusetsusaponin V inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA], TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 , PMID:25073091 N-nitrosodiethylamine multiple interactions ISO RGD:621758 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CASP12 mRNA more ... CTD PMID:17602206 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of CASP12 mRNA CTD PMID:24535843 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP12 mRNA CTD PMID:24535843 N-nitrosodimethylamine increases expression ISO RGD:621758 6480464 Dimethylnitrosamine results in increased expression of CASP12 mRNA CTD PMID:25380136 nickel sulfate increases expression ISO RGD:621758 6480464 nickel sulfate results in increased expression of CASP12 mRNA, nickel sulfate results in increased expression of CASP12 protein CTD PMID:28296042 nickel sulfate multiple interactions ISO RGD:621758 6480464 Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA] more ... CTD PMID:28296042 nicotine multiple interactions ISO RGD:621758 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 ochratoxin A increases expression ISO RGD:621758 6480464 ochratoxin A results in increased expression of CASP12 mRNA CTD PMID:23208426 paclitaxel decreases expression ISO RGD:1348077 6480464 Paclitaxel results in decreased expression of CASP12 protein CTD PMID:17701358 paclitaxel multiple interactions ISO RGD:1348077 6480464 [Tretinoin co-treated with Paclitaxel] results in increased expression of CASP12 protein CTD PMID:17701358 paclitaxel increases expression ISO RGD:1348077 6480464 Paclitaxel results in increased expression of CASP12 protein CTD PMID:18098270 paracetamol increases cleavage EXP 6480464 Acetaminophen results in increased cleavage of CASP12 protein CTD PMID:14747384 paracetamol multiple interactions EXP 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [Acetaminophen results in increased expression of CASP12 mRNA] CTD PMID:12540782 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CASP12 mRNA CTD PMID:12540782 paraoxon multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] more ... CTD PMID:20079824 paraoxon increases expression EXP 6480464 Paraoxon results in increased expression of CASP12 protein CTD PMID:20079824 paraquat multiple interactions ISO RGD:621758 6480464 Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein], NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of CASP12 mRNA] CTD PMID:22245251 , PMID:22678742 paraquat increases activity ISO RGD:621758 6480464 Paraquat results in increased activity of CASP12 protein CTD PMID:24912633 paraquat increases expression ISO RGD:621758 6480464 Paraquat results in increased expression of CASP12 mRNA, Paraquat results in increased expression of CASP12 protein CTD PMID:22678742 paraquat increases degradation ISO RGD:621758 6480464 Paraquat results in increased degradation of CASP12 protein CTD PMID:22245251 perfluorooctanoic acid increases expression ISO RGD:621758 6480464 perfluorooctanoic acid results in increased expression of CASP12 mRNA CTD PMID:16221955 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP12 mRNA, NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CASP12 mRNA] CTD PMID:19482888 , PMID:24535843 phenobarbital multiple interactions ISO RGD:621758 6480464 [DMU-212 co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of CASP12 mRNA CTD PMID:27048571 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CASP12 mRNA CTD PMID:19482888 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1348077 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 procaine multiple interactions EXP 6480464 Procaine inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 quartz increases expression ISO RGD:1348077 6480464 Quartz results in increased expression of CASP12 protein CTD PMID:29729927 quercetin multiple interactions ISO RGD:1348077 6480464 [temozolomide co-treated with Quercetin] results in increased expression of CASP12 protein CTD PMID:24126416 resveratrol multiple interactions ISO RGD:1348077 6480464 CASP12 mutant form inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] more ... CTD PMID:24224909 , PMID:24264887 resveratrol affects expression ISO RGD:621758 6480464 resveratrol affects the expression of CASP12 mRNA CTD PMID:17959022 resveratrol increases expression ISO RGD:1348077 6480464 resveratrol results in increased expression of CASP12 protein CTD PMID:24264887 rotenone increases expression EXP 6480464 Rotenone results in increased expression of CASP12 mRNA CTD PMID:25428620 rotenone multiple interactions ISO RGD:621758 6480464 salubrinal inhibits the reaction [Rotenone results in increased cleavage of CASP12 protein] CTD PMID:26446018 rotenone increases cleavage ISO RGD:621758 6480464 Rotenone results in increased cleavage of CASP12 protein CTD PMID:26446018 rotenone increases activity EXP 6480464 Rotenone results in increased activity of CASP12 protein CTD PMID:17459145 rotenone multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased activity of CASP12 protein], salubrinal inhibits the reaction [Rotenone results in increased expression of CASP12 mRNA] CTD PMID:17459145 , PMID:25428620 rubimaillin increases activity ISO RGD:1348077 6480464 rubimaillin results in increased activity of CASP12 protein CTD PMID:19716835 rubimaillin multiple interactions ISO RGD:1348077 6480464 BCL2L1 protein inhibits the reaction [rubimaillin results in increased activity of CASP12 protein] CTD PMID:19716835 ruthenium red multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 S-adenosyl-L-methioninate decreases expression EXP 6480464 S-Adenosylmethionine results in decreased expression of CASP12 mRNA CTD PMID:18098314 S-adenosyl-L-methionine decreases expression EXP 6480464 S-Adenosylmethionine results in decreased expression of CASP12 mRNA CTD PMID:18098314 salubrinal multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] more ... CTD PMID:21616140 , PMID:25428620 salubrinal multiple interactions ISO RGD:621758 6480464 salubrinal inhibits the reaction [arsenite results in increased activity of CASP12 protein], salubrinal inhibits the reaction [Rotenone results in increased cleavage of CASP12 protein] CTD PMID:18226606 , PMID:26446018 simvastatin multiple interactions ISO RGD:1348077 6480464 Simvastatin results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:19253821 sirolimus decreases cleavage EXP 6480464 Sirolimus results in decreased cleavage of CASP12 protein CTD PMID:20511674 sirolimus multiple interactions ISO RGD:621758 6480464 Sirolimus inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein] CTD PMID:29870746 sodium arsenite multiple interactions ISO RGD:621758 6480464 Melatonin inhibits the reaction [sodium arsenite results in decreased expression of CASP12 protein], Melatonin inhibits the reaction [sodium arsenite results in increased activity of CASP12 protein] CTD PMID:17645694 , PMID:18715270 sodium arsenite decreases expression ISO RGD:621758 6480464 sodium arsenite results in decreased expression of CASP12 protein CTD PMID:17645694 , PMID:17681577 sodium arsenite increases activity ISO RGD:621758 6480464 sodium arsenite results in increased activity of CASP12 protein CTD PMID:18715270 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of CASP12 mRNA CTD PMID:30225638 streptozocin increases cleavage EXP 6480464 Streptozocin results in increased cleavage of CASP12 protein CTD PMID:24967692 streptozocin multiple interactions ISO RGD:621758 6480464 Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:25541178 streptozocin increases cleavage ISO RGD:621758 6480464 Streptozocin results in increased cleavage of CASP12 protein CTD PMID:25541178 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CASP12 protein modified form CTD PMID:23499715 streptozocin multiple interactions EXP 6480464 FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form], sulforafan inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:23499715 , PMID:24967692 succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CASP12 mRNA CTD PMID:26378955 sulforaphane multiple interactions EXP 6480464 sulforafan inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:24967692 sulfur dioxide multiple interactions ISO RGD:621758 6480464 Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 tauroursodeoxycholic acid multiple interactions ISO RGD:1348077 6480464 tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein] CTD PMID:12198651 temozolomide multiple interactions ISO RGD:1348077 6480464 [temozolomide co-treated with Quercetin] results in increased expression of CASP12 protein CTD PMID:24126416 temozolomide increases expression ISO RGD:1348077 6480464 temozolomide results in increased expression of CASP12 protein CTD PMID:24126416 TEMPO multiple interactions ISO RGD:621758 6480464 TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA], TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] CTD PMID:28296042 tetrachloromethane affects expression ISO RGD:621758 6480464 Carbon Tetrachloride affects the expression of CASP12 protein CTD PMID:16092975 tetrachloromethane increases expression ISO RGD:621758 6480464 Carbon Tetrachloride results in increased expression of CASP12 mRNA CTD PMID:31150632 thapsigargin multiple interactions ISO RGD:1348077 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form] more ... CTD PMID:12198651 more ... thapsigargin increases expression ISO RGD:1348077 6480464 Thapsigargin results in increased expression of CASP12 protein modified form CTD PMID:26264395 thapsigargin increases activity ISO RGD:1348077 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:24224909 thapsigargin increases activity ISO RGD:621758 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:18477628 thapsigargin increases cleavage ISO RGD:621758 6480464 Thapsigargin results in increased cleavage of CASP12 protein alternative form CTD PMID:16338971 thapsigargin increases activity EXP 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:20493918 thapsigargin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein], Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of CASP12 protein modified form] CTD PMID:20493918 , PMID:27638049 thapsigargin increases cleavage ISO RGD:1348077 6480464 Thapsigargin results in increased cleavage of CASP12 protein CTD PMID:12198651 thioacetamide multiple interactions ISO RGD:621758 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CASP12 mRNA CTD PMID:23830814 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of CASP12 mRNA CTD PMID:27760801 tributylstannane increases expression ISO RGD:621758 6480464 tributyltin results in increased expression of CASP12 protein CTD PMID:26079211 trichlorfon multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] more ... CTD PMID:19631781 trichostatin A decreases expression ISO RGD:621758 6480464 trichostatin A results in decreased expression of CASP12 mRNA CTD PMID:23558232 Triptolide increases expression EXP 6480464 triptolide results in increased expression of CASP12 protein CTD PMID:26990902 tunicamycin increases cleavage EXP 6480464 Tunicamycin results in increased cleavage of CASP12 protein CTD PMID:17003819 tunicamycin increases activity ISO RGD:1348077 6480464 Tunicamycin results in increased activity of CASP12 protein CTD PMID:24224909 tunicamycin multiple interactions ISO RGD:1348077 6480464 resveratrol inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:24224909 tunicamycin increases activity ISO RGD:621758 6480464 Tunicamycin results in increased activity of CASP12 protein CTD PMID:18477628 tunicamycin multiple interactions ISO RGD:621758 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 urethane decreases expression EXP 6480464 Urethane results in decreased expression of CASP12 protein CTD PMID:12400877 verapamil multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 vorinostat multiple interactions ISO RGD:1348077 6480464 [vorinostat co-treated with Cisplatin] results in increased activity of CASP12 protein CTD PMID:19280190 zinc atom increases expression ISO RGD:621758 6480464 Zinc deficiency results in increased expression of CASP12 mRNA CTD PMID:19111725 zinc dichloride multiple interactions ISO RGD:1348077 6480464 [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 zinc oxide increases expression ISO RGD:621758 6480464 Zinc Oxide results in increased expression of CASP12 mRNA CTD PMID:23232460 zinc oxide increases activity EXP 6480464 Zinc Oxide analog results in increased activity of CASP12 protein CTD PMID:25680694 zinc(0) increases expression ISO RGD:621758 6480464 Zinc deficiency results in increased expression of CASP12 mRNA CTD PMID:19111725
Gene-Chemical Interaction Annotations
