Casp12 (caspase 12) - Rat Genome Database

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Gene: Casp12 (caspase 12) Mus musculus
Analyze
Symbol: Casp12
Name: caspase 12
RGD ID: 731442
MGI Page MGI
Description: Exhibits cysteine-type endopeptidase activity. Involved in endoplasmic reticulum unfolded protein response; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and self proteolysis. Localizes to endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human CASP12 (caspase 12 (gene/pseudogene)); PARTICIPATES IN Alzheimer's disease pathway; amyotrophic lateral sclerosis pathway; apoptotic cell death pathway; INTERACTS WITH (+)-dexrazoxane; (S)-nicotine; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CASP-12; caspase-12
RGD Orthologs
Human
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3995,345,419 - 5,373,034 (+)NCBIGRCm39mm39
GRCm39 Ensembl95,345,430 - 5,373,032 (+)Ensembl
GRCm3895,345,442 - 5,373,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl95,345,430 - 5,373,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv3795,345,476 - 5,373,034 (+)NCBIGRCm37mm9NCBIm37
MGSCv3695,345,502 - 5,373,034 (+)NCBImm8
Celera3117,331,063 - 117,358,628 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-pilocarpine  (ISO)
(+)-Tetrandrine  (ISO)
(R)-noradrenaline  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-aminoethoxydiphenylborane  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4,5,3',4',5'-Hexachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-aminophenol  (ISO)
4-phenylbutyric acid  (EXP,ISO)
acetamide  (ISO)
acrylamide  (EXP)
acrylonitrile  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-naphthoflavone  (EXP)
aluminium atom  (EXP)
aluminium(0)  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (EXP)
arsenic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
BAPTA  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (EXP)
brefeldin A  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
Chikusetsusaponin-V  (ISO)
chloroacetic acid  (EXP)
chlorohydrocarbon  (ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
chromium(6+)  (ISO)
cimetidine  (EXP)
cisplatin  (EXP,ISO)
citric acid  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
corticosterone  (ISO)
curcumin  (EXP,ISO)
D-glucose  (EXP)
DDE  (ISO)
demethoxycurcumin  (ISO)
desferrioxamine B  (ISO)
Diacetoxyscirpenol  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP)
doxorubicin  (EXP,ISO)
edaravone  (ISO)
emodin  (EXP)
endosulfan  (ISO)
ethanol  (EXP,ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP)
excitatory amino acid agonist  (EXP)
fisetin  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
furosemide  (ISO)
geneticin  (ISO)
gentamycin  (ISO)
glucose  (EXP)
GW 4064  (EXP)
heparin  (EXP)
hydralazine  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroxamic acid  (ISO)
icosanoid  (ISO)
iron(III) nitrilotriacetate  (ISO)
isoflurane  (ISO)
ketoconazole  (EXP)
KN-93  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
manganese(II) chloride  (EXP,ISO)
meglumine amidotrizoate  (ISO)
melatonin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (ISO)
minocycline  (ISO)
Mitotane  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP,ISO)
ochratoxin A  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
paraoxon  (EXP)
paraquat  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
poly(guanylic acid)  (ISO)
potassium dichromate  (ISO)
procaine  (EXP)
quartz  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rimonabant  (EXP)
rotenone  (EXP,ISO)
rubimaillin  (ISO)
ruthenium red  (ISO)
S-adenosyl-L-methioninate  (EXP)
S-adenosyl-L-methionine  (EXP)
salubrinal  (EXP,ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
streptozocin  (EXP,ISO)
succimer  (EXP)
sulforaphane  (EXP)
sulfur dioxide  (ISO)
tauroursodeoxycholic acid  (ISO)
temozolomide  (ISO)
TEMPO  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (ISO)
thymoquinone  (ISO)
titanium dioxide  (EXP)
tributylstannane  (ISO)
trichlorfon  (ISO)
trichostatin A  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
tunicamycin  (EXP,ISO)
urethane  (EXP)
verapamil  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc oxide  (EXP,ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Atkin JD, etal., J Biol Chem. 2006 Oct 6;281(40):30152-65. Epub 2006 Jul 17.
2. Biswas J, etal., Cell Signal. 2018 Jan;42:211-226. doi: 10.1016/j.cellsig.2017.10.018. Epub 2017 Nov 7.
3. Blas-Valdivia V, etal., Acta Histochem. 2015 Oct;117(8):811-9. doi: 10.1016/j.acthis.2015.07.003. Epub 2015 Jul 31.
4. Cai J, etal., Neurosci Lett. 2008 Aug 22;441(2):167-72. Epub 2008 May 24.
5. Chen J, etal., Neurosci Lett. 2008 Oct 10;443(3):134-9. Epub 2008 Jul 26.
6. Dong Y, etal., Int J Clin Exp Pathol. 2015 Dec 1;8(12):15871-8. eCollection 2015.
7. Duan XC, etal., CNS Neurosci Ther. 2017 Jul;23(7):554-566. doi: 10.1111/cns.12703. Epub 2017 May 19.
8. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
9. Kubisch CH, etal., Am J Physiol Gastrointest Liver Physiol. 2006 Aug;291(2):G238-45. Epub 2006 Mar 30.
10. Lakshmanan AP, etal., Int J Biochem Cell Biol. 2013 Feb;45(2):438-47. doi: 10.1016/j.biocel.2012.09.017. Epub 2012 Sep 29.
11. Larner SF, etal., J Neurochem. 2004 Jan;88(1):78-90.
12. Li JH, etal., Hepatobiliary Pancreat Dis Int. 2018 Feb;17(1):32-38. doi: 10.1016/j.hbpd.2018.01.006. Epub 2018 Feb 2.
13. Li SS, etal., Ren Fail. 2015 Jun;37(5):890-5. doi: 10.3109/0886022X.2015.1015427. Epub 2015 Feb 24.
14. Li Y, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2014 Jan;37(1):30-5.
15. Liu Y, etal., Zhonghua Gan Zang Bing Za Zhi. 2005 Aug;13(8):563-6.
16. Liu Y, etal., Zhonghua Xin Xue Guan Bing Za Zhi. 2016 Jun 24;44(6):494-500.
17. Lu JF, etal., Fa Yi Xue Za Zhi. 2018 Aug;34(4):347-351. doi: 10.12116/j.issn.1004-5619.2018.04.001. Epub 2018 Aug 25.
18. MGD data from the GO Consortium
19. MGD IEA
20. Mouw G, etal., Neuroreport 2003 Feb 10;14(2):183-6.
21. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
22. Pipeline to import KEGG annotations from KEGG into RGD
23. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
24. RGD automated import pipeline
25. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26. RGD automated import pipeline for gene-chemical interactions
27. Sima AA and Li ZG, Diabetes. 2005 May;54(5):1497-505.
28. Sun HL, etal., Exp Clin Endocrinol Diabetes. 2009 Jul;117(7):336-44. Epub 2009 Mar 19.
29. Sun Y, etal., Acta Biochim Pol. 2008;55(3):511-6. Epub 2008 Sep 12.
30. Sun Y, etal., Curr Vasc Pharmacol. 2017;15(2):174-183. doi: 10.2174/1570161114666161025100656.
31. Wan S, etal., Neurol Res. 2009 Feb 11.
32. Wang D, etal., Neurourol Urodyn. 2017 Jan;36(1):65-72. doi: 10.1002/nau.22886. Epub 2015 Sep 14.
33. Wiberg R, etal., Neuroreport. 2018 Jun 13;29(9):779-785. doi: 10.1097/WNR.0000000000001031.
34. Yan Z, etal., Sheng Li Xue Bao. 2017 Aug 25;69(4):367-377.
35. Yang H, etal., Autophagy. 2020 Feb;16(2):271-288. doi: 10.1080/15548627.2019.1606647. Epub 2019 Apr 21.
36. Yu B, etal., BMC Neurosci. 2014 Oct 21;15:115. doi: 10.1186/s12868-014-0115-5.
37. Yu H, etal., J Cell Mol Med. 2016 Apr;20(4):623-31. doi: 10.1111/jcmm.12739. Epub 2016 Feb 12.
38. Zhang GG, etal., Peptides. 2009 Jun;30(6):1109-16. Epub 2009 May 3.
39. Zhang H, etal., Neurosci Bull. 2008 Feb;24(1):7-12.
40. Zhao Y, etal., Zhonghua Yi Xue Za Zhi. 2014 Oct 21;94(38):3024-8.
Additional References at PubMed
PMID:9038361   PMID:10087912   PMID:10349636   PMID:10377054   PMID:10618441   PMID:10638761   PMID:10739653   PMID:10882126   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11278723  
PMID:11526440   PMID:11964391   PMID:12045204   PMID:12097332   PMID:12477932   PMID:12699784   PMID:12847083   PMID:14532116   PMID:14561754   PMID:15059849   PMID:15210718   PMID:15313203  
PMID:15489334   PMID:15542627   PMID:15701691   PMID:15880263   PMID:15975932   PMID:15996037   PMID:16141072   PMID:16141073   PMID:16566922   PMID:16597616   PMID:16625199   PMID:16954146  
PMID:17088543   PMID:17245644   PMID:17394578   PMID:17399692   PMID:17913437   PMID:18309324   PMID:18329614   PMID:19000842   PMID:19164919   PMID:19801895   PMID:20057499   PMID:20226691  
PMID:20299359   PMID:20368330   PMID:20818395   PMID:20876354   PMID:21086719   PMID:21677750   PMID:21873635   PMID:22212133   PMID:22869374   PMID:24879640   PMID:25561786   PMID:25943459  
PMID:26207309   PMID:26494620   PMID:26582949   PMID:27251234   PMID:28082356   PMID:29943814   PMID:30154447  


Genomics

Comparative Map Data
Casp12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3995,345,419 - 5,373,034 (+)NCBIGRCm39mm39
GRCm39 Ensembl95,345,430 - 5,373,032 (+)Ensembl
GRCm3895,345,442 - 5,373,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl95,345,430 - 5,373,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv3795,345,476 - 5,373,034 (+)NCBIGRCm37mm9NCBIm37
MGSCv3695,345,502 - 5,373,034 (+)NCBImm8
Celera3117,331,063 - 117,358,628 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
CASP12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11104,885,718 - 104,898,670 (-)EnsemblGRCh38hg38GRCh38
GRCh3811104,885,718 - 104,898,460 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711104,756,445 - 104,769,187 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611104,262,627 - 104,274,607 (-)NCBINCBI36hg18NCBI36
Build 3411104,262,626 - 104,274,607NCBI
Cytogenetic Map11q22.3NCBI
HuRef11100,688,549 - 100,700,548 (-)NCBIHuRef
CHM1_111104,639,398 - 104,652,341 (-)NCBICHM1_1
Casp12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.282,642,296 - 2,669,549 (+)NCBI
Rnor_6.0 Ensembl82,659,865 - 2,686,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.082,658,892 - 2,686,160 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.082,680,961 - 2,711,365 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.482,082,933 - 2,110,511 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.182,082,932 - 2,110,511 (+)NCBI
Celera84,241,433 - 4,268,684 (+)NCBICelera
Cytogenetic Map8q11NCBI
CASP12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1527,162,840 - 27,176,964 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl527,161,700 - 27,177,683 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha527,093,663 - 27,107,789 (+)NCBI
ROS_Cfam_1.0527,199,590 - 27,213,717 (+)NCBI
UMICH_Zoey_3.1527,241,103 - 27,255,223 (+)NCBI
UNSW_CanFamBas_1.0527,127,410 - 27,141,630 (+)NCBI
UU_Cfam_GSD_1.0527,286,329 - 27,300,448 (+)NCBI

Position Markers
Casp12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A1UniSTS
cM Map91.11UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902908Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130430544Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:834
Count of miRNA genes:410
Interacting mature miRNAs:470
Transcripts:ENSMUST00000027009, ENSMUST00000138308, ENSMUST00000149520, ENSMUST00000151332, ENSMUST00000151788
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC104914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC141637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY675223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY675224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027009   ⟹   ENSMUSP00000027009
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl95,345,430 - 5,373,032 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138308
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl95,345,496 - 5,354,448 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149520
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl95,345,479 - 5,353,445 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151332   ⟹   ENSMUSP00000122201
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl95,345,504 - 5,358,823 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151788   ⟹   ENSMUSP00000121565
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl95,345,476 - 5,372,881 (+)Ensembl
RefSeq Acc Id: NM_009808   ⟹   NP_033938
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3995,345,476 - 5,373,034 (+)NCBI
GRCm3895,345,476 - 5,373,034 (+)NCBI
MGSCv3795,345,476 - 5,373,034 (+)RGD
Celera3117,331,063 - 117,358,628 (-)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509840   ⟹   XP_006509903
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3995,345,419 - 5,372,651 (+)NCBI
GRCm3895,345,442 - 5,372,651 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036154581   ⟹   XP_036010474
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3995,345,568 - 5,372,651 (+)NCBI
RefSeq Acc Id: XM_036154582   ⟹   XP_036010475
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3995,345,580 - 5,372,651 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_033938   ⟸   NM_009808
- UniProtKB: O08736 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006509903   ⟸   XM_006509840
- Peptide Label: isoform X3
- UniProtKB: E9Q575 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000027009   ⟸   ENSMUST00000027009
RefSeq Acc Id: ENSMUSP00000121565   ⟸   ENSMUST00000151788
RefSeq Acc Id: ENSMUSP00000122201   ⟸   ENSMUST00000151332
RefSeq Acc Id: XP_036010474   ⟸   XM_036154581
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036010475   ⟸   XM_036154582
- Peptide Label: isoform X2
Protein Domains
CARD   CASPASE_P10   CASPASE_P20

Promoters
RGD ID:6844284
Promoter ID:MM_KWN:56303
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   MEF_B4,   MEF_B6
Transcripts:NM_009808,   OTTMUST00000084912,   OTTMUST00000084914,   OTTMUST00000084915,   OTTMUST00000084916
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3695,345,286 - 5,345,786 (+)MPROMDB
RGD ID:8668734
Promoter ID:EPDNEW_M12398
Type:initiation region
Name:Casp12_1
Description:Mus musculus caspase 12 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3895,345,498 - 5,345,558EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1312922 AgrOrtholog
Ensembl Genes ENSMUSG00000025887 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000027009 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000121565 UniProtKB/TrEMBL
  ENSMUSP00000122201 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027009 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000151332 UniProtKB/TrEMBL
  ENSMUST00000151788 UniProtKB/TrEMBL
InterPro CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase_his_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12364 UniProtKB/Swiss-Prot
MGD MGI:1312922 ENTREZGENE
NCBI Gene 12364 ENTREZGENE
PANTHER PTHR10454 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10454:SF134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Casp12 PhenoGen
PRINTS IL1BCENZYME UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CASc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CASPC_MOUSE UniProtKB/Swiss-Prot
  D6RCG7_MOUSE UniProtKB/TrEMBL
  E9Q575 ENTREZGENE, UniProtKB/TrEMBL
  O08736 ENTREZGENE
  Q6B836_MOUSE UniProtKB/TrEMBL
  Q6B837_MOUSE UniProtKB/TrEMBL
  Q8BQQ5_MOUSE UniProtKB/TrEMBL
  Q8BSX6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TT82 UniProtKB/Swiss-Prot