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Gene: Casp12 (caspase 12) Mus musculus
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Symbol: Casp12
Name: caspase 12
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity; cysteine-type peptidase activity (ortholog); endopeptidase activity (ortholog); INVOLVED IN apoptotic process; endoplasmic reticulum unfolded protein response; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; PARTICIPATES IN Alzheimer's disease pathway; amyotrophic lateral sclerosis pathway; apoptotic cell death pathway; ASSOCIATED WITH abnormal locomotor coordination; decreased sensitivity to induced cell death; decreased susceptibility to bacterial infection; ASSOCIATED WITH Acute Liver Failure (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN endoplasmic reticulum; cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (+)-dexrazoxane; (S)-nicotine; 1,1-dichloroethene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CASP-12; caspase-12
Orthologs:
Homo sapiens (human) : CASP12 (caspase 12 (gene/pseudogene))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp12 (caspase 12)  Alliance
Canis lupus familiaris (dog) : CASP12 (caspase 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3895,345,442 - 5,373,034 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3795,345,476 - 5,373,034 (+)NCBIGRCm37mm9NCBIm37
MGSCv3695,345,502 - 5,373,034 (+)NCBImm8
Celera3117,331,063 - 117,358,628 (-)NCBICelera
Cytogenetic Map9 A1NCBI
cM Map92.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Casp12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731442
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.