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Gene: Mapk3 (mitogen-activated protein kinase 3) Mus musculus
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Symbol: Mapk3
Name: mitogen-activated protein kinase 3
Description: Exhibits MAP kinase activity; MAP kinase kinase activity; and phosphotyrosine residue binding activity. Involved in several processes, including Bergmann glial cell differentiation; animal organ development; and positive regulation of cellular metabolic process. Localizes to the cytosol; nucleus; and pseudopodium. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and nervous system. Orthologous to human MAPK3 (mitogen-activated protein kinase 3); PARTICIPATES IN ceramide signaling pathway; endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH (+)-alpha-viniferin; (+)-catechin; (+)-pilocarpine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Erk-1; Erk1; Ert2; Esrk1; extracellular signal-regulated kinase 1; insulin-stimulated MAP2 kinase; MAP kinase 3; microtubule-associated protein 2 kinase; Mnk1; Mtap2k; p44; p44 MAP kinase; p44erk1; p44mapk; pp42/MAP kinase; Prkm3
Orthologs:
Homo sapiens (human) : MAPK3 (mitogen-activated protein kinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapk3 (mitogen activated protein kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk3 (mitogen-activated protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK3 (mitogen-activated protein kinase 3)
Canis lupus familiaris (dog) : MAPK3 (mitogen-activated protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk3 (mitogen-activated protein kinase 3)
Sus scrofa (pig) : MAPK3 (mitogen-activated protein kinase 3)
more info ...
Related Pseudogenes: Gm14854   Gm18659   Gm18661   Gm5675  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm387126,759,626 - 126,765,816 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377133,903,140 - 133,909,330 (+)NCBIGRCm37mm9NCBIm37
MGSCv367126,550,780 - 126,556,964 (+)NCBImm8
Celera7126,607,166 - 126,613,155 (+)NCBICelera
Cytogenetic Map7 F3NCBI
cM Map769.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model