Mapk3 (mitogen-activated protein kinase 3) - Rat Genome Database
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Gene: Mapk3 (mitogen-activated protein kinase 3) Mus musculus
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Symbol: Mapk3
Name: mitogen-activated protein kinase 3
RGD ID: 619571
MGI Page MGI
Description: Exhibits MAP kinase activity; MAP kinase kinase activity; and phosphotyrosine residue binding activity. Involved in several processes, including animal organ development; positive regulation of macromolecule metabolic process; and positive regulation of response to external stimulus. Localizes to cytosol; nucleus; and pseudopodium. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and nervous system. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3); PARTICIPATES IN ceramide signaling pathway; endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH (+)-alpha-tocopherol; (+)-alpha-viniferin; (+)-catechin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Erk; Erk-; Erk-1; Erk1; Ert2; Esr; Esrk1; extracellular signal-regulated kinase 1; insulin-stimulated MAP2 kinase; MAP kinase 3; microtubule-associated protein 2 kinase; Mnk1; Mtap; Mtap2k; p44; p44 MAP kinase; p44er; p44erk1; p44m; p44mapk; pp42/MAP kinase; Prk; Prkm3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm14854   Gm18659   Gm18661   Gm5675  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,358,798 - 126,364,988 (+)NCBIGRCm39mm39
GRCm387126,759,626 - 126,765,816 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,759,601 - 126,765,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv377133,903,140 - 133,909,330 (+)NCBIGRCm37mm9NCBIm37
MGSCv367126,550,780 - 126,556,964 (+)NCBImm8
Celera7126,607,166 - 126,613,154 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model