Apoa1 (apolipoprotein A-I) - Rat Genome Database

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Gene: Apoa1 (apolipoprotein A-I) Mus musculus
Symbol: Apoa1
Name: apolipoprotein A-I
RGD ID: 10173
Description: Enables several functions, including cholesterol transfer activity; high-density lipoprotein particle binding activity; and identical protein binding activity. Acts upstream of or within several processes, including cholesterol biosynthetic process; cholesterol efflux; and regulation of intestinal cholesterol absorption. Located in extracellular space. Is expressed in embryo; intestine; liver; and stomach. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial visceral amyloidosis; hypolipoproteinemia (multiple); non-alcoholic steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Al; Alp-1; Ap; apo-AI; Apoa-1; apoA-I; apolipoprotein A1; Brp-; Brp-14; Ltw-; Ltw-1; Lvtw; Lvtw-1; MGC102525; Se; Sep; Sep-1; Sep-2; Sep2
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39946,139,928 - 46,141,767 (+)NCBIGRCm39mm39
GRCm39 Ensembl946,139,878 - 46,141,764 (+)Ensembl
GRCm38946,228,630 - 46,230,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl946,228,580 - 46,230,466 (+)EnsemblGRCm38mm10GRCm38
MGSCv37946,036,713 - 46,038,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36945,979,705 - 45,981,461 (+)NCBImm8
Celera943,517,584 - 43,519,420 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map925.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
Acute Tubulointerstitial Nephritis  (ISO)
adenocarcinoma  (ISO)
Alzheimer's disease  (ISO)
arteriosclerosis  (ISO)
atherosclerosis  (ISO)
Behcet's disease  (ISO)
Budd-Chiari syndrome  (ISO)
cardiomyopathy  (ISO)
cardiovascular system disease  (ISO)
cerebral amyloid angiopathy  (IMP)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (ISO)
Chronic Hepatitis B  (ISO)
chronic kidney disease  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Death  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
Drug Eruptions  (ISO)
Dwarfism  (ISO)
Edema  (ISO)
end stage renal disease  (IDA,ISO)
Endotoxemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Familial Amyloid Polyneuropathies  (ISO)
Familial Amyloidosis  (ISO)
familial isolated deficiency of vitamin E  (ISO)
familial visceral amyloidosis  (ISO)
fatty liver disease  (ISO)
hepatitis C  (ISO)
hepatoblastoma  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hypercholesterolemia  (ISO)
Hyperlipoproteinemia Type II  (ISO)
hypertension  (ISO)
hyperthyroidism  (ISO)
Hypertriglyceridemia  (ISO)
Hypoalphalipoproteinemias  (ISO)
hypolipoproteinemia  (ISO)
Hypoproteinemia  (ISO)
Hypoxia  (ISO)
idiopathic pulmonary fibrosis  (ISO)
Inflammation  (ISO)
intellectual disability  (ISO)
Kidney Reperfusion Injury  (ISO)
lipid metabolism disorder  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
major depressive disorder  (ISO)
malignant mesothelioma  (ISO)
membranous glomerulonephritis  (ISO)
Metabolic Syndrome  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
nephrotic syndrome  (ISO)
non-alcoholic fatty liver disease  (IMP)
non-alcoholic steatohepatitis  (ISO)
obesity  (IEP,ISO)
ocular hypertension  (ISO)
pancreatic cancer  (ISO)
Parkinson's disease  (ISO)
Pediatric Obesity  (ISO)
polycystic kidney disease  (IGI)
primary hypoalphalipoproteinemia 1  (ISO)
primary hypoalphalipoproteinemia 2  (ISO)
pulmonary fibrosis  (IEP)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (IDA,ISO)
Tangier disease  (ISO)
transitional cell carcinoma  (ISO)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-taxifolin  (ISO)
(-)-ephedrine  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-bromohexadecanoic acid  (ISO)
26-hydroxycholesterol  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP,ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arachidonic acid  (ISO)
aristolochic acid  (ISO)
atazanavir sulfate  (ISO)
atenolol  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-D-glucosamine  (ISO)
bezafibrate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bucladesine  (EXP)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caesium atom  (ISO)
caffeine  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
cholesterol  (EXP,ISO)
choline  (ISO)
chromium atom  (ISO)
chromium trinitrate  (EXP)
chromium(6+)  (EXP)
ciprofibrate  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
Clofop  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (ISO)
cyproterone acetate  (ISO)
D-glucose  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
dichlorine  (ISO)
diethyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
disodium selenite  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ezetimibe  (ISO)
fenofibrate  (EXP,ISO)
fingolimod hydrochloride  (ISO)
flavonoids  (ISO)
folic acid  (EXP,ISO)
folpet  (EXP)
fonofos  (ISO)
fructose  (EXP,ISO)
fulvestrant  (ISO)
gemfibrozil  (EXP,ISO)
genistein  (ISO)
ginsenoside Rf  (EXP)
glucose  (ISO)
glutathione  (EXP)
glyburide  (ISO)
glycerol  (ISO)
glycidol  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycolaldehyde  (EXP)
glyoxal  (EXP)
GW 4064  (EXP,ISO)
GW 501516  (EXP,ISO)
GW 7647  (ISO)
high-density lipoprotein cholesterol  (EXP,ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
linalool  (ISO)
linoleic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lovastatin  (ISO)
mastoparan  (ISO)
menadione  (EXP)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
morphine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
Nandrolone decanoate  (ISO)
nefazodone  (ISO)
nevirapine  (ISO)
nickel atom  (ISO)
nicotinic acid  (EXP,ISO)
nifedipine  (ISO)
nitrofen  (ISO)
nitroglycerin  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
p-menthan-3-ol  (ISO)
palmitoleic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
PCB138  (ISO)
pentetic acid  (ISO)
perfluorobutyric acid  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
pirinixic acid  (EXP,ISO)
Polyoxyethylene dioleate  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
probucol  (EXP)
propanal  (ISO)
prostaglandin E2  (ISO)
prostaglandin J2  (ISO)
Ptaquiloside  (EXP)
pyrazinecarboxamide  (ISO)
pyrogallol  (EXP)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
resveratrol  (ISO)
rosuvastatin calcium  (ISO)
rotenone  (ISO)
salicylates  (ISO)
sarin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (EXP,ISO)
stigmasterol  (EXP)
streptozocin  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tartrazine  (ISO)
taurocholic acid  (ISO)
tauroursodeoxycholic acid  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
tolcapone  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
U-73122  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
warfarin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (IMP)
animal organ regeneration  (ISO)
axon regeneration  (IGI)
blood vessel endothelial cell migration  (IMP)
cholesterol biosynthetic process  (IBA,IMP)
cholesterol efflux  (IBA,IDA,IMP,ISO)
cholesterol homeostasis  (IBA,ISO)
cholesterol import  (ISO)
cholesterol metabolic process  (IGI,IMP,ISO)
cholesterol transport  (IDA,IMP,ISO)
endothelial cell proliferation  (IMP)
ERK1 and ERK2 cascade  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
glucocorticoid metabolic process  (IMP)
high-density lipoprotein particle assembly  (IBA,ISO)
high-density lipoprotein particle remodeling  (ISO)
integrin-mediated signaling pathway  (ISO)
lipid metabolic process  (IEA)
lipid storage  (IMP)
lipid transport  (IEA)
lipoprotein biosynthetic process  (IGI,IMP)
lipoprotein metabolic process  (IBA)
negative chemotaxis  (ISO)
negative regulation of cell adhesion molecule production  (ISO)
negative regulation of cytokine production involved in immune response  (ISO)
negative regulation of heterotypic cell-cell adhesion  (ISO)
negative regulation of hydrolase activity  (IGI)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-1 beta production  (ISO)
negative regulation of lipase activity  (ISO)
negative regulation of response to cytokine stimulus  (ISO)
negative regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
negative regulation of very-low-density lipoprotein particle remodeling  (ISO)
peptidyl-methionine modification  (ISO)
peripheral nervous system axon regeneration  (ISO)
phosphatidylcholine biosynthetic process  (ISO)
phosphatidylcholine metabolic process  (IBA)
phospholipid efflux  (IBA,ISO)
phospholipid homeostasis  (ISO)
phospholipid metabolic process  (IMP)
phospholipid transport  (ISO)
positive regulation of cholesterol efflux  (ISO)
positive regulation of cholesterol esterification  (IBA,ISO)
positive regulation of fatty acid biosynthetic process  (IBA)
positive regulation of hydrolase activity  (ISO)
positive regulation of lipid biosynthetic process  (IBA)
positive regulation of lipoprotein lipase activity  (IBA)
positive regulation of phagocytosis  (ISO)
positive regulation of phospholipid efflux  (ISO)
positive regulation of Rho protein signal transduction  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of substrate adhesion-dependent cell spreading  (ISO)
positive regulation of triglyceride catabolic process  (IBA)
protein localization  (IMP)
protein oxidation  (ISO)
protein stabilization  (ISO)
regulation of Cdc42 protein signal transduction  (ISO)
regulation of intestinal cholesterol absorption  (IBA,IDA)
regulation of protein phosphorylation  (IDA)
response to estrogen  (ISO)
response to nutrient  (ISO)
response to xenobiotic stimulus  (ISO)
reverse cholesterol transport  (IBA,ISO)
steroid metabolic process  (IEA)
transforming growth factor beta receptor signaling pathway  (ISO)
triglyceride homeostasis  (IBA,ISO)
very-low-density lipoprotein particle remodeling  (IBA)
vitamin transport  (ISO)


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Additional References at PubMed
PMID:447069   PMID:478292   PMID:1280258   PMID:1352323   PMID:1477475   PMID:1478650   PMID:1496008   PMID:1596360   PMID:1596514   PMID:1639271   PMID:1703299   PMID:1768618  
PMID:1917889   PMID:1981995   PMID:2138915   PMID:2175917   PMID:2383242   PMID:2499515   PMID:2512252   PMID:2576007   PMID:2792009   PMID:2885918   PMID:3085096   PMID:3132994  
PMID:3729925   PMID:3749510   PMID:3865183   PMID:3866909   PMID:4980192   PMID:6099394   PMID:6403543   PMID:6457599   PMID:6572912   PMID:6735174   PMID:6785912   PMID:6800944  
PMID:6929943   PMID:7295297   PMID:7387621   PMID:7411019   PMID:7488287   PMID:7615825   PMID:7751823   PMID:7798939   PMID:7803821   PMID:8049247   PMID:8075642   PMID:8105016  
PMID:8241102   PMID:8268669   PMID:8281015   PMID:8288233   PMID:8482578   PMID:8560269   PMID:8631787   PMID:8647961   PMID:8661715   PMID:8672132   PMID:8672141   PMID:8682656  
PMID:8798380   PMID:8827514   PMID:8833906   PMID:8940144   PMID:9144079   PMID:9160753   PMID:9186920   PMID:9275209   PMID:9300780   PMID:9325076   PMID:9327769   PMID:9415807  
PMID:9416903   PMID:9507992   PMID:9611252   PMID:9616220   PMID:9684752   PMID:9743230   PMID:9795222   PMID:9832509   PMID:10049364   PMID:10073953   PMID:10087289   PMID:10349636  
PMID:10357841   PMID:10521374   PMID:10549415   PMID:10559220   PMID:10559507   PMID:10632725   PMID:10652269   PMID:10766851   PMID:10866673   PMID:10926756   PMID:11002334   PMID:11042159  
PMID:11076861   PMID:11093738   PMID:11116096   PMID:11217851   PMID:11278646   PMID:11371557   PMID:11477092   PMID:11478940   PMID:11701467   PMID:11744719   PMID:11983814   PMID:11991719  
PMID:12000760   PMID:12050168   PMID:12062424   PMID:12117740   PMID:12181325   PMID:12231556   PMID:12231569   PMID:12235173   PMID:12351695   PMID:12401887   PMID:12466851   PMID:12471038  
PMID:12477932   PMID:12488454   PMID:12511593   PMID:12547832   PMID:12748967   PMID:12810823   PMID:12829028   PMID:12859204   PMID:12869555   PMID:12928428   PMID:12937162   PMID:12951361  
PMID:14592847   PMID:14595002   PMID:14610273   PMID:14643015   PMID:14729855   PMID:14974682   PMID:14983036   PMID:14993246   PMID:14999024   PMID:15060137   PMID:15102887   PMID:15188057  
PMID:15210842   PMID:15265030   PMID:15269218   PMID:15375180   PMID:15466405   PMID:15489334   PMID:15520446   PMID:15520449   PMID:15604097   PMID:15632021   PMID:15649902   PMID:15654758  
PMID:15793583   PMID:15797865   PMID:15834127   PMID:15911702   PMID:15922294   PMID:15995171   PMID:16061955   PMID:16099465   PMID:16109169   PMID:16141072   PMID:16141073   PMID:16151025  
PMID:16204232   PMID:16245952   PMID:16285990   PMID:16339487   PMID:16423356   PMID:16497661   PMID:16498401   PMID:16554055   PMID:16931800   PMID:17071966   PMID:17206937   PMID:17222401  
PMID:17389516   PMID:17534071   PMID:17615369   PMID:17615385   PMID:17634284   PMID:17681174   PMID:17711302   PMID:17906976   PMID:17916774   PMID:17928634   PMID:17936760   PMID:18033752  
PMID:18042552   PMID:18188184   PMID:18205410   PMID:18218986   PMID:18246469   PMID:18385134   PMID:18403724   PMID:18458046   PMID:18508577   PMID:18540024   PMID:18554416   PMID:18617288  
PMID:18678879   PMID:18722179   PMID:18767813   PMID:18775511   PMID:19106236   PMID:19120689   PMID:19239199   PMID:19286630   PMID:19423573   PMID:19433476   PMID:19433579   PMID:19538736  
PMID:19636841   PMID:19786567   PMID:20193037   PMID:20360851   PMID:20376577   PMID:20430747   PMID:20498409   PMID:20537649   PMID:20637749   PMID:20817832   PMID:20833724   PMID:20974999  
PMID:21267068   PMID:21288012   PMID:21482781   PMID:21504968   PMID:21600874   PMID:21622630   PMID:21677750   PMID:21756353   PMID:21771977   PMID:21858084   PMID:21870882   PMID:21873635  
PMID:21889608   PMID:21944998   PMID:21968112   PMID:22259189   PMID:22267484   PMID:22402133   PMID:22427535   PMID:22576368   PMID:22652597   PMID:22666383   PMID:22805347   PMID:22845860  
PMID:23055941   PMID:23118226   PMID:23132909   PMID:23322769   PMID:23425306   PMID:23429073   PMID:23456478   PMID:23499549   PMID:23581552   PMID:23658016   PMID:23720750   PMID:23889245  
PMID:23920041   PMID:23990662   PMID:24123812   PMID:24170386   PMID:24219083   PMID:24334873   PMID:24407029   PMID:24464187   PMID:24520415   PMID:24523407   PMID:24603680   PMID:24650562  
PMID:24759932   PMID:24797128   PMID:25117703   PMID:25415591   PMID:25465389   PMID:25550459   PMID:25561462   PMID:25593328   PMID:25948084   PMID:25969427   PMID:25982508   PMID:26044581  
PMID:26170061   PMID:26279300   PMID:26368306   PMID:26466956   PMID:26510953   PMID:26556891   PMID:26989082   PMID:27088511   PMID:27105909   PMID:27150392   PMID:27199144   PMID:27514935  
PMID:27647324   PMID:27806983   PMID:27890613   PMID:28378742   PMID:28577569   PMID:28981086   PMID:28982731   PMID:28986362   PMID:29074589   PMID:29183962   PMID:29578333   PMID:29618729  
PMID:29991652   PMID:30104731   PMID:30290792   PMID:30635405   PMID:30742993   PMID:30821416   PMID:31002190   PMID:31084613   PMID:31101050   PMID:31336888   PMID:31907281   PMID:32325033  
PMID:32477466   PMID:32681583   PMID:32759326   PMID:32810603   PMID:33020907   PMID:33309975   PMID:33827950   PMID:34270107   PMID:34348153  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39946,139,928 - 46,141,767 (+)NCBIGRCm39mm39
GRCm39 Ensembl946,139,878 - 46,141,764 (+)Ensembl
GRCm38946,228,630 - 46,230,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl946,228,580 - 46,230,466 (+)EnsemblGRCm38mm10GRCm38
MGSCv37946,036,713 - 46,038,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36945,979,705 - 45,981,461 (+)NCBImm8
Celera943,517,584 - 43,519,420 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map925.36NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl11116,835,751 - 116,837,622 (-)EnsemblGRCh38hg38GRCh38
GRCh3811116,835,751 - 116,837,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711116,706,467 - 116,708,666 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611116,211,679 - 116,213,548 (-)NCBINCBI36hg18NCBI36
Celera11113,864,272 - 113,866,141 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11112,638,728 - 112,640,597 (-)NCBIHuRef
CHM1_111116,591,221 - 116,593,090 (-)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2846,527,251 - 46,529,035 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl846,527,144 - 46,529,035 (+)Ensembl
Rnor_6.0850,525,091 - 50,526,875 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl850,525,091 - 50,526,875 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0849,151,163 - 49,152,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera846,109,311 - 46,111,065 (+)NCBICelera
RH 3.4 Map8472.0RGD
Cytogenetic Map8q22NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495541218,170,331 - 18,172,298 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541218,170,331 - 18,172,298 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.111115,606,136 - 115,608,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11115,606,136 - 115,608,122 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011111,673,539 - 111,675,428 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1516,740,071 - 16,742,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl516,740,130 - 16,741,943 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha516,792,234 - 16,794,244 (+)NCBI
ROS_Cfam_1.0516,686,357 - 16,688,357 (+)NCBI
UMICH_Zoey_3.1516,823,454 - 16,825,453 (+)NCBI
UNSW_CanFamBas_1.0516,726,037 - 16,728,039 (+)NCBI
UU_Cfam_GSD_1.0516,768,944 - 16,770,956 (+)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440494799,189,637 - 99,191,475 (-)NCBI
SpeTri2.0NW_0049365422,111,055 - 2,112,626 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl944,216,393 - 44,218,978 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1944,216,481 - 44,218,360 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2949,288,730 - 49,290,611 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9p12-p11NCBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.11108,201,967 - 108,203,902 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1108,201,439 - 108,203,609 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604317,846,715 - 17,848,683 (+)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_00462478412,249,283 - 12,251,215 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,230,130 - 46,230,326UniSTSGRCm38
MGSCv37946,038,213 - 46,038,409UniSTSGRCm37
Celera943,519,084 - 43,519,280UniSTS
Cytogenetic Map9A2-A4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37946,037,061 - 46,037,929UniSTSGRCm37
Celera943,517,932 - 43,518,800UniSTS
Cytogenetic Map9A2-A4UniSTS
cM Map927.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,228,709 - 46,229,046UniSTSGRCm38
MGSCv37946,036,792 - 46,037,129UniSTSGRCm37
Celera943,517,663 - 43,518,000UniSTS
Cytogenetic Map9A2-A4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,228,709 - 46,229,148UniSTSGRCm38
MGSCv37946,036,792 - 46,037,231UniSTSGRCm37
Celera943,517,663 - 43,518,102UniSTS
Cytogenetic Map9A2-A4UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A2-A4UniSTS
cM Map927.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,228,978 - 46,229,846UniSTSGRCm38
MGSCv37946,037,061 - 46,037,929UniSTSGRCm37
Celera943,517,932 - 43,518,800UniSTS
Cytogenetic Map9A2-A4UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91245867446458818Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91347987947479879Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91550045549500594Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91550045549500594Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91550045549500594Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91550045549500594Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91583833149838331Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91583833149838331Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91583833149838331Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91610000050100000Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91610000050100000Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91679834550798345Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91706754451067647Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined92003211054032229Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92024206654242196Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92039490154395074Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92039490154395074Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92039490154395074Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92039490154395074Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92094144454941444Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92500000069000000Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92567618959676285Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92567618959676285Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92567618959676285Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92567618959676285Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92688512460885255Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92688512460885255Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92688512460885255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92733989761340026Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92938163163381774Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92938163163381774Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93014186664141979Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93082861764828723Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93252326366523557Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93254112166541246Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93259987266600121Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93297840266978536Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93319972567199840Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93406754473531973Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93512317869123299Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93512317869123299Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93512317869123299Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93682494749509211Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93703211050199840Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93791224471912244Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93819229172192291Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93819229172192291Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93819229172192291Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93949260173492601Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94050829851897370Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94050829874700643Mouse
11532693Sluc39_msusceptibility to lung cancer 39 (mouse)94073407848440176Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94089776474897921Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94357343177573577Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94357343177573577Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94452089278520980Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:329
Count of miRNA genes:278
Interacting mature miRNAs:301
Transcripts:ENSMUST00000034588, ENSMUST00000132155
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.



Nucleotide Sequences
RefSeq Transcripts NM_009692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU755007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L04149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L04151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S80442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034588   ⟹   ENSMUSP00000034588
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl946,139,878 - 46,141,764 (+)Ensembl
GRCm38.p6 Ensembl946,228,580 - 46,230,466 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132155   ⟹   ENSMUSP00000150525
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl946,140,019 - 46,141,271 (+)Ensembl
GRCm38.p6 Ensembl946,228,721 - 46,229,973 (+)Ensembl
RefSeq Acc Id: NM_009692   ⟹   NP_033822
RefSeq Status: REVIEWED
Mouse AssemblyChrPosition (strand)Source
GRCm39946,139,928 - 46,141,767 (+)NCBI
GRCm38946,228,630 - 46,230,469 (+)NCBI
MGSCv37946,036,713 - 46,038,549 (+)RGD
Celera943,517,584 - 43,519,423 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_033822   ⟸   NM_009692
- Peptide Label: preproprotein
- UniProtKB: Q00623 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034588   ⟸   ENSMUST00000034588
RefSeq Acc Id: ENSMUSP00000150525   ⟸   ENSMUST00000132155

RGD ID:6844173
Promoter ID:MM_KWN:57217
SO ACC ID:SO:0000170
Tissues & Cell Lines:Brain,   Liver,   Lung
Transcripts:OTTMUST00000071093,   OTTMUST00000071094
Mouse AssemblyChrPosition (strand)Source
MGSCv36946,036,839 - 46,037,339 (+)MPROMDB
RGD ID:6848908
Promoter ID:MM_TRO:9972
SO ACC ID:SO:0000170
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Mouse AssemblyChrPosition (strand)Source
MGSCv36946,037,441 - 46,038,342 (+)MPROMDB
RGD ID:8669476
Promoter ID:EPDNEW_M12769
Type:initiation region
Description:Mus musculus apolipoprotein A-I , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm38946,228,709 - 46,228,769EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88049 AgrOrtholog
Ensembl Genes ENSMUSG00000032083 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034588 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000150525 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034588 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000132155 UniProtKB/TrEMBL
InterPro ApoA_E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11806 UniProtKB/Swiss-Prot
Pfam Apolipoprotein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Apoa1 PhenoGen
UniProt Secondary O08855 UniProtKB/Swiss-Prot
  O09042 UniProtKB/Swiss-Prot
  Q8BPD5 UniProtKB/Swiss-Prot