Esr1 Mouse (-)-bursehernin affects binding ISO ESR1 (Homo sapiens) 6480464 bursehernin binds to ESR1 protein CTD PMID:35631411 Esr1 Mouse (-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of ESR1 protein CTD PMID:34600025 and PMID:35863485 Esr1 Mouse (-)-matairesinol affects binding ISO ESR1 (Homo sapiens) 6480464 matairesinol binds to ESR1 protein CTD PMID:35631411 Esr1 Mouse (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ESR1 mRNA CTD PMID:36331819 Esr1 Mouse (2,4,5-trichlorophenoxy)acetic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:16626760 Esr1 Mouse (24S)-24-hydroxycholesterol multiple interactions ISO ESR1 (Homo sapiens) 6480464 24-hydroxycholesterol binds to and results in decreased activity of ESR1 protein and 24-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17873880 Esr1 Mouse (25R)-cholest-5-ene-3beta,26-diol multiple interactions EXP 6480464 ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA] and ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] CTD PMID:17873880 Esr1 Mouse (25R)-cholest-5-ene-3beta,26-diol affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to 27-hydroxycholesterol CTD PMID:17873880 Esr1 Mouse (25R)-cholest-5-ene-3beta,26-diol increases degradation ISO ESR1 (Homo sapiens) 6480464 27-hydroxycholesterol results in increased degradation of ESR1 protein CTD PMID:17872378 Esr1 Mouse (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO ESR1 (Homo sapiens) 6480464 27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR1 protein more ... CTD PMID:17872378 and PMID:17873880 Esr1 Mouse (3-phenoxyphenyl)methanol multiple interactions ISO ESR1 (Homo sapiens) 6480464 3-phenoxybenzylalcohol binds to and results in increased activity of ESR1 protein CTD PMID:16395479 and PMID:33049310 Esr1 Mouse (3-phenoxyphenyl)methanol decreases expression ISO ESR1 (Homo sapiens) 6480464 3-phenoxybenzylalcohol results in decreased expression of ESR1 mRNA CTD PMID:20397420 Esr1 Mouse (E)-thiamethoxam decreases expression EXP 6480464 Thiamethoxam results in decreased expression of ESR1 protein CTD PMID:33533595 Esr1 Mouse (E)-thiamethoxam affects binding ISO ESR1 (Homo sapiens) 6480464 Thiamethoxam binds to ESR1 protein CTD PMID:31550567 Esr1 Mouse (R)-camphor multiple interactions ISO ESR1 (Homo sapiens) 6480464 Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse (R)-linalyl acetate increases activity ISO ESR1 (Homo sapiens) 6480464 linalyl acetate results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse (R)-linalyl acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 Esr1 Mouse (R)-salsolinol increases activity ISO ESR1 (Homo sapiens) 6480464 salsolinol results in increased activity of ESR1 protein CTD PMID:24020587 Esr1 Mouse (R,R,R)-alpha-tocopherol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA] and [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 Esr1 Mouse (S)-colchicine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Colchicine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse (S)-naringenin affects activity ISO ESR1 (Homo sapiens) 6480464 naringenin affects the activity of ESR1 protein CTD PMID:15185748 Esr1 Mouse (S)-naringenin increases expression ISO ESR1 (Homo sapiens) 6480464 naringenin metabolite results in increased expression of ESR1 mRNA and naringenin results in increased expression of ESR1 mRNA CTD PMID:30153467 and PMID:36235125 Esr1 Mouse (S)-naringenin decreases expression ISO ESR1 (Homo sapiens) 6480464 naringenin results in decreased expression of ESR1 mRNA more ... CTD PMID:24586459 and PMID:30153467 Esr1 Mouse (S)-naringenin affects binding ISO ESR1 (Homo sapiens) 6480464 naringenin binds to ESR1 protein CTD PMID:19913605 and PMID:22692793 Esr1 Mouse (S)-naringenin affects binding EXP 6480464 naringenin binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse (S)-naringenin affects binding ISO Esr1 (Rattus norvegicus) 6480464 naringenin binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse (S)-naringenin increases activity ISO ESR1 (Homo sapiens) 6480464 naringenin results in increased activity of ESR1 protein CTD PMID:10854714 and PMID:16118406 Esr1 Mouse (S)-naringenin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naringenin binds to ESR1 protein] which results in increased activity of ALPL protein more ... CTD PMID:10397250 more ... Esr1 Mouse (S)-nicotine decreases expression ISO ESR1 (Homo sapiens) 6480464 Nicotine results in decreased expression of ESR1 mRNA CTD PMID:27552315 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects binding EXP 6480464 2 more ... CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects activity EXP 6480464 2 more ... CTD PMID:21251949 and PMID:23611293 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases activity ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:20143881 more ... Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:10579340 and PMID:25549949 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases response to substance EXP 6480464 ESR1 protein results in increased susceptibility to 2 more ... CTD PMID:21252393 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 [Estradiol co-treated with 2 more ... CTD PMID:10965916 more ... Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression EXP 6480464 2 more ... CTD PMID:11509743 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects binding ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:10579340 more ... Esr1 Mouse 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases response to substance EXP 6480464 ESR1 protein results in increased susceptibility to 1 more ... CTD PMID:21252393 Esr1 Mouse 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane multiple interactions EXP 6480464 ESR1 protein affects the susceptibility to [1 more ... CTD PMID:21252393 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o more ... CTD PMID:11922773 more ... Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression EXP 6480464 o and p'-DDT results in decreased expression of ESR1 mRNA CTD PMID:28263910 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases activity ISO ESR1 (Homo sapiens) 6480464 o and p'-DDT results in increased activity of ESR1 protein CTD PMID:15064155 more ... Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects binding ISO Esr1 (Rattus norvegicus) 6480464 o and p'-DDT binds to ESR1 protein CTD PMID:11086226 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [o more ... CTD PMID:28531659 and PMID:9860891 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases activity ISO Esr1 (Rattus norvegicus) 6480464 o and p'-DDT results in increased activity of ESR1 protein CTD PMID:28531659 and PMID:9860891 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects binding EXP 6480464 o and p'-DDT binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO ESR1 (Homo sapiens) 6480464 o and p'-DDT results in increased expression of ESR1 mRNA CTD PMID:11922773 Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO ESR1 (Homo sapiens) 6480464 o more ... CTD PMID:11867264 more ... Esr1 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects binding ISO ESR1 (Homo sapiens) 6480464 o and p'-DDT binds to ESR1 protein CTD PMID:12676605 more ... Esr1 Mouse 1,1-dichloroethene decreases expression EXP 6480464 vinylidene chloride results in decreased expression of ESR1 mRNA CTD PMID:26682919 Esr1 Mouse 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of ESR1 mRNA CTD PMID:26388957 Esr1 Mouse 1,3-dichlorobenzene increases activity ISO ESR1 (Homo sapiens) 6480464 1 and 3-dichlorobenzene results in increased activity of ESR1 protein CTD PMID:12558164 Esr1 Mouse 1,4-dichlorobenzene increases activity ISO ESR1 (Homo sapiens) 6480464 4-dichlorobenzene results in increased activity of ESR1 protein CTD PMID:12558164 Esr1 Mouse 1,4-dithiothreitol multiple interactions ISO ESR1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Dithiothreitol results in increased activity of ESR1 protein] and Tamoxifen inhibits the reaction [Dithiothreitol results in increased activity of ESR1 protein] CTD PMID:22403704 Esr1 Mouse 1-(3-(trifluoromethyl)phenyl)piperazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:23026265 Esr1 Mouse 1-Amino-2,4-dibromoanthraquinone multiple interactions ISO ESR1 (Homo sapiens) 6480464 1-amino-2 and 4-dibromoanthraquinone binds to and results in increased activity of ESR1 protein CTD PMID:20707409 Esr1 Mouse 1-bromopropane multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CCN5 mRNA] and ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA] CTD PMID:23384675 Esr1 Mouse 1-chloro-2,4-dinitrobenzene affects expression ISO ESR1 (Homo sapiens) 6480464 Dinitrochlorobenzene affects the expression of ESR1 mRNA CTD PMID:19527780 Esr1 Mouse 1-Hydroxypyrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 1-hydroxypyrene binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 10H-phenothiazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 phenothiazine binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 16alpha-Bromo-17beta-estradiol affects binding ISO ESR1 (Homo sapiens) 6480464 16 alpha-bromo-17 beta-estradiol binds to ESR1 protein CTD PMID:9751507 Esr1 Mouse 16alpha-Bromo-17beta-estradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 16 alpha-bromo-17 beta-estradiol inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:9751507 Esr1 Mouse 17alpha-ethynylestradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of SCARB1 protein modified form] more ... CTD PMID:17559906 more ... Esr1 Mouse 17alpha-ethynylestradiol increases expression ISO ESR1 (Homo sapiens) 6480464 Ethinyl Estradiol results in increased expression of ESR1 mRNA CTD PMID:29783106 Esr1 Mouse 17alpha-ethynylestradiol increases methylation EXP 6480464 Ethinyl Estradiol results in increased methylation of ESR1 exon CTD PMID:31463084 Esr1 Mouse 17alpha-ethynylestradiol increases activity ISO ESR1 (Homo sapiens) 6480464 Ethinyl Estradiol results in increased activity of ESR1 protein CTD PMID:11331656 more ... Esr1 Mouse 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ESR1 mRNA and Ethinyl Estradiol results in increased expression of ESR1 protein CTD PMID:16606610 more ... Esr1 Mouse 17alpha-ethynylestradiol affects binding ISO ESR1 (Homo sapiens) 6480464 Ethinyl Estradiol binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse 17alpha-ethynylestradiol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Ethinyl Estradiol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse 17alpha-ethynylestradiol affects binding EXP 6480464 Ethinyl Estradiol binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 17alpha-ethynylestradiol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of ESR1 protein CTD PMID:11731036 more ... Esr1 Mouse 17alpha-ethynylestradiol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of ESR1 more ... CTD PMID:11218048 more ... Esr1 Mouse 17alpha-ethynylestradiol increases activity ISO Esr1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse 17alpha-ethynylestradiol affects expression ISO Esr1 (Rattus norvegicus) 6480464 Ethinyl Estradiol affects the expression of ESR1 mRNA CTD PMID:20170705 Esr1 Mouse 17alpha-ethynylestradiol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR1 mRNA more ... CTD PMID:17161848 more ... Esr1 Mouse 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ESR1 mRNA CTD PMID:17942748 Esr1 Mouse 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of ESR1 mRNA CTD PMID:17555576 Esr1 Mouse 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA] more ... CTD PMID:12072388 more ... Esr1 Mouse 17alpha-hydroxyprogesterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 17-alpha-Hydroxyprogesterone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 17beta-estradiol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of ESR1 protein] more ... CTD PMID:10433208 more ... Esr1 Mouse 17beta-estradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 (+)-JQ1 compound inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to XBP1 promoter]] more ... CTD PMID:10922479 more ... Esr1 Mouse 17beta-estradiol affects expression ISO ESR1 (Homo sapiens) 6480464 Estradiol affects the expression of ESR1 mRNA and Estradiol affects the expression of ESR1 protein CTD PMID:28880708 and PMID:30664189 Esr1 Mouse 17beta-estradiol increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to Estradiol CTD PMID:29134746 and PMID:29890199 Esr1 Mouse 17beta-estradiol increases activity ISO ESR1 (Homo sapiens) 6480464 Estradiol analog results in increased activity of ESR1 protein more ... CTD PMID:11331656 more ... Esr1 Mouse 17beta-estradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 more ... CTD PMID:10397250 more ... Esr1 Mouse 17beta-estradiol affects localization ISO ESR1 (Homo sapiens) 6480464 Estradiol affects the localization of ESR1 protein CTD PMID:15947004 more ... Esr1 Mouse 17beta-estradiol increases expression ISO ESR1 (Homo sapiens) 6480464 Estradiol results in increased expression of ESR1 mRNA more ... CTD PMID:11922773 more ... Esr1 Mouse 17beta-estradiol affects expression ISO Esr1 (Rattus norvegicus) 6480464 Estradiol affects the expression of ESR1 mRNA and Estradiol affects the expression of ESR1 protein CTD PMID:22389237 and PMID:27463640 Esr1 Mouse 17beta-estradiol increases splicing ISO Esr1 (Rattus norvegicus) 6480464 Estradiol results in increased splicing of ESR1 mRNA CTD PMID:24236210 Esr1 Mouse 17beta-estradiol affects activity EXP 6480464 Estradiol affects the activity of ESR1 protein CTD PMID:23611293 Esr1 Mouse 17beta-estradiol affects response to substance EXP 6480464 ESR1 affects the susceptibility to Estradiol CTD PMID:10709760 Esr1 Mouse 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of ESR1 mRNA and Estradiol results in decreased expression of ESR1 protein CTD PMID:11145618 more ... Esr1 Mouse 17beta-estradiol increases activity ISO Esr1 (Rattus norvegicus) 6480464 Estradiol results in increased activity of ESR1 protein CTD PMID:11750080 more ... Esr1 Mouse 17beta-estradiol increases abundance EXP 6480464 ESR1 protein mutant form results in increased abundance of Estradiol CTD PMID:22989549 Esr1 Mouse 17beta-estradiol increases ubiquitination ISO ESR1 (Homo sapiens) 6480464 Estradiol results in increased ubiquitination of ESR1 protein CTD PMID:12612060 Esr1 Mouse 17beta-estradiol increases degradation ISO ESR1 (Homo sapiens) 6480464 Estradiol results in increased degradation of ESR1 protein CTD PMID:10922479 more ... Esr1 Mouse 17beta-estradiol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Estradiol results in increased expression of ESR1 mRNA more ... CTD PMID:12062901 more ... Esr1 Mouse 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ESR1 mRNA more ... CTD PMID:10825672 more ... Esr1 Mouse 17beta-estradiol affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 mRNA affects the susceptibility to Estradiol and ESR1 protein affects the susceptibility to Estradiol CTD PMID:17275032 more ... Esr1 Mouse 17beta-estradiol decreases response to substance EXP 6480464 ESR1 protein mutant form results in decreased susceptibility to Estradiol CTD PMID:19920132 Esr1 Mouse 17beta-estradiol affects binding EXP 6480464 Estradiol binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse 17beta-estradiol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Estradiol binds to ESR1 protein CTD PMID:11086226 more ... Esr1 Mouse 17beta-estradiol increases activity EXP 6480464 Estradiol results in increased activity of ESR1 protein CTD PMID:18446233 more ... Esr1 Mouse 17beta-estradiol decreases expression ISO ESR1 (Homo sapiens) 6480464 Estradiol results in decreased expression of ESR1 more ... CTD PMID:11867264 more ... Esr1 Mouse 17beta-estradiol affects localization ISO Esr1 (Rattus norvegicus) 6480464 Estradiol affects the localization of ESR1 protein CTD PMID:19479021 Esr1 Mouse 17beta-estradiol increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of ESR1 protein and Estradiol results in increased phosphorylation of ESR1 protein alternative form CTD PMID:12441364 more ... Esr1 Mouse 17beta-estradiol affects binding ISO ESR1 (Homo sapiens) 6480464 [Estradiol binds to ESR1 protein] which binds to NCOA2 protein more ... CTD PMID:10964929 more ... Esr1 Mouse 17beta-estradiol affects activity ISO ESR1 (Homo sapiens) 6480464 Estradiol affects the activity of ESR1 protein CTD PMID:18635651 Esr1 Mouse 17beta-estradiol affects abundance ISO ESR1 (Homo sapiens) 6480464 ESR1 gene polymorphism affects the abundance of Estradiol CTD PMID:16061840 Esr1 Mouse 17beta-estradiol increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 Estradiol results in increased phosphorylation of ESR1 protein CTD PMID:17323972 Esr1 Mouse 17beta-estradiol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of ESR1 mRNA more ... CTD PMID:12008023 more ... Esr1 Mouse 17beta-estradiol affects activity ISO Esr1 (Rattus norvegicus) 6480464 Estradiol affects the activity of ESR1 protein CTD PMID:15746884 Esr1 Mouse 17beta-estradiol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 3-phenoxybenzoic acid inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] more ... CTD PMID:10580743 more ... Esr1 Mouse 17beta-estradiol 17-glucosiduronic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of ESR1 protein CTD PMID:25813982 Esr1 Mouse 17beta-estradiol 3-benzoate affects expression ISO Esr1 (Rattus norvegicus) 6480464 estradiol 3-benzoate affects the expression of ESR1 mRNA CTD PMID:15925091 and PMID:19350480 Esr1 Mouse 17beta-estradiol 3-benzoate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 methyl palmitate inhibits the reaction [estradiol 3-benzoate results in increased expression of ESR1 protein] CTD PMID:32967526 Esr1 Mouse 17beta-estradiol 3-benzoate affects binding EXP 6480464 estradiol 3-benzoate binds to ESR1 protein CTD PMID:11162928 Esr1 Mouse 17beta-estradiol 3-benzoate increases expression ISO Esr1 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased expression of ESR1 mRNA and estradiol 3-benzoate results in increased expression of ESR1 protein CTD PMID:15716488 more ... Esr1 Mouse 17beta-estradiol 3-benzoate increases methylation ISO Esr1 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased methylation of ESR1 exon and estradiol 3-benzoate results in increased methylation of ESR1 intron CTD PMID:22016562 Esr1 Mouse 17beta-estradiol 3-benzoate affects binding ISO ESR1 (Homo sapiens) 6480464 estradiol 3-benzoate binds to ESR1 protein CTD PMID:11162928 Esr1 Mouse 17beta-estradiol 3-benzoate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in decreased expression of ESR1 and estradiol 3-benzoate results in decreased expression of ESR1 protein CTD PMID:15375486 and PMID:15778002 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Dihydrotestosterone co-treated with Estradiol] results in decreased expression of ESR1 protein more ... CTD PMID:12676605 more ... Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Dihydrotestosterone results in increased phosphorylation of ESR1 protein CTD PMID:25969534 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO ESR1 (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of ESR1 protein alternative form CTD PMID:25969534 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to Dihydrotestosterone CTD PMID:22275727 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one affects binding EXP 6480464 Dihydrotestosterone binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one affects binding ISO ESR1 (Homo sapiens) 6480464 Dihydrotestosterone binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse 17beta-hydroxy-5alpha-androstan-3-one increases activity ISO Esr1 (Rattus norvegicus) 6480464 Dihydrotestosterone results in increased activity of ESR1 protein CTD PMID:11750080 Esr1 Mouse 1H-pyrazole affects binding ISO ESR1 (Homo sapiens) 6480464 pyrazole analog binds to ESR1 protein CTD PMID:17909483 Esr1 Mouse 2,2',4,4',5,5'-hexachlorobiphenyl affects binding ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:16293362 Esr1 Mouse 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [[Hydrocarbons more ... CTD PMID:31923581 Esr1 Mouse 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:23756648 more ... Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:29112739 Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:26988655 Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases activity ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:19672399 Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:23398518 more ... Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 ESR1 gene mutant form inhibits the reaction [2 more ... CTD PMID:29112739 Esr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether decreases response to substance EXP 6480464 ESR1 gene mutant form results in decreased susceptibility to 2 more ... CTD PMID:29112739 Esr1 Mouse 2,2',4,5'-Tetrabromodiphenyl ether multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:23603053 Esr1 Mouse 2,2'-Bisphenol F multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 and 2'-bisphenol F binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 2,2'-Dihydroxy-4-methoxybenzophenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 dioxybenzone binds to and results in increased activity of ESR1 protein CTD PMID:16079615 Esr1 Mouse 2,2':5',2''-terthiophene affects binding ISO ESR1 (Homo sapiens) 6480464 alpha-terthienyl analog binds to ESR1 protein CTD PMID:27999363 Esr1 Mouse 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene affects binding ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:14579009 more ... Esr1 Mouse 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene affects binding EXP 6480464 2 more ... CTD PMID:19913605 Esr1 Mouse 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:14579009 Esr1 Mouse 2,3,3',4,4',5-Hexachlorobiphenyl affects binding ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:16293362 Esr1 Mouse 2,3,4,5-Tetrachloro-4'-biphenylol multiple interactions ISO ESR1 (Homo sapiens) 6480464 2' more ... CTD PMID:10964929 and PMID:11530281 Esr1 Mouse 2,3,4,5-Tetrachloro-4'-biphenylol affects binding ISO ESR1 (Homo sapiens) 6480464 2' more ... CTD PMID:10964929 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ESR1 mRNA CTD PMID:21570461 and PMID:24058054 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Esr1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of ESR1 mRNA CTD PMID:23238561 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ESR1 mRNA and Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein CTD PMID:12612060 more ... Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases degradation ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased degradation of ESR1 protein CTD PMID:10922479 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases ubiquitination ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased ubiquitination of ESR1 protein CTD PMID:12612060 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to Tetrachlorodibenzodioxin CTD PMID:11281733 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of ESR1 mRNA CTD PMID:20348232 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased activity of ESR1 protein CTD PMID:19574409 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ESR1 mRNA and Tetrachlorodibenzodioxin results in increased expression of ESR1 protein CTD PMID:11399792 more ... Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ESR1 mRNA CTD PMID:16254025 more ... Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 CGA protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ESR1 protein] CTD PMID:12128104 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases activity EXP 6480464 Tetrachlorodibenzodioxin results in decreased activity of ESR1 protein CTD PMID:17991765 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:12612060 more ... Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ESR1 mRNA and Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein CTD PMID:12021401 more ... Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO ESR1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of ESR1 mRNA and Tetrachlorodibenzodioxin affects the expression of ESR1 protein CTD PMID:17960587 and PMID:22298810 Esr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein] more ... CTD PMID:10922479 more ... Esr1 Mouse 2,3-bis(4-hydroxyphenyl)propionitrile multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:19264808 and PMID:24425189 Esr1 Mouse 2,4,5-trichlorophenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:33049310 Esr1 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:19672399 more ... Esr1 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO Esr1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:16414171 Esr1 Mouse 2,4-Dihydroxybenzophenone increases expression ISO ESR1 (Homo sapiens) 6480464 2 and 4-dihydroxybenzophenone analog results in increased expression of ESR1 mRNA CTD PMID:18973785 Esr1 Mouse 2,4-Dihydroxybenzophenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:11823001 more ... Esr1 Mouse 2,4-Dihydroxybenzophenone affects binding ISO ESR1 (Homo sapiens) 6480464 2 and 4-dihydroxybenzophenone binds to ESR1 protein CTD PMID:11823001 and PMID:19913605 Esr1 Mouse 2,6-diisopropylnaphthalene multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 and 6-diisopropylnaphthalene binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse 2,6-dimethylnaphthalene multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 and 6-dimethylnaphthalene binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse 2-acetamidofluorene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 2-Acetylaminofluorene results in decreased expression of ESR1 mRNA CTD PMID:19167416 Esr1 Mouse 2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-amino-(1 more ... CTD PMID:16533016 Esr1 Mouse 2-Aminoanthraquinone multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-aminoanthraquinone binds to and results in increased activity of ESR1 protein CTD PMID:20707409 Esr1 Mouse 2-benzyl-4-chlorophenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 clorophene binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 2-benzyl-4-chlorophenol affects activity EXP 6480464 clorophene affects the activity of ESR1 protein CTD PMID:21251949 Esr1 Mouse 2-hydroxy-17beta-estradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] CTD PMID:9048584 Esr1 Mouse 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester multiple interactions ISO ESR1 (Homo sapiens) 6480464 homosalate binds to and results in increased activity of ESR1 protein and Polystyrenes promotes the reaction [homosalate results in increased expression of ESR1 mRNA] CTD PMID:24004914 and PMID:38381479 Esr1 Mouse 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester increases expression ISO ESR1 (Homo sapiens) 6480464 homosalate results in increased expression of ESR1 mRNA CTD PMID:38381479 Esr1 Mouse 2-hydroxyestrone affects binding ISO ESR1 (Homo sapiens) 6480464 2-hydroxyestrone binds to ESR1 protein CTD PMID:16728493 Esr1 Mouse 2-hydroxyestrone multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-hydroxyestrone binds to and results in increased activity of ESR1 protein CTD PMID:17713618 Esr1 Mouse 2-methoxyethanol increases expression ISO Esr1 (Rattus norvegicus) 6480464 methyl cellosolve results in increased expression of ESR1 mRNA CTD PMID:19643169 Esr1 Mouse 2-sec-butylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 2-sec-butylphenol binds to ESR1 protein CTD PMID:12598185 Esr1 Mouse 2-tert-butylhydroquinone multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-tert-butylhydroquinone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 2-tert-Butylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 2-tert-butylphenol binds to ESR1 protein CTD PMID:12598185 and PMID:19913605 Esr1 Mouse 22-Hydroxycholesterol multiple interactions ISO ESR1 (Homo sapiens) 6480464 22-hydroxycholesterol binds to and results in decreased activity of ESR1 protein and 22-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17873880 Esr1 Mouse 25-hydroxycholesterol multiple interactions ISO ESR1 (Homo sapiens) 6480464 25-hydroxycholesterol binds to and results in decreased activity of ESR1 protein and 25-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17873880 Esr1 Mouse 26-hydroxycholesterol increases degradation ISO ESR1 (Homo sapiens) 6480464 27-hydroxycholesterol results in increased degradation of ESR1 protein CTD PMID:17872378 Esr1 Mouse 26-hydroxycholesterol multiple interactions ISO ESR1 (Homo sapiens) 6480464 27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR1 protein more ... CTD PMID:17872378 and PMID:17873880 Esr1 Mouse 26-hydroxycholesterol affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to 27-hydroxycholesterol CTD PMID:17873880 Esr1 Mouse 26-hydroxycholesterol multiple interactions EXP 6480464 ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA] and ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] CTD PMID:17873880 Esr1 Mouse 3',5'-cyclic AMP multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein] more ... CTD PMID:19766106 and PMID:20360387 Esr1 Mouse 3',5'-cyclic AMP increases activity ISO ESR1 (Homo sapiens) 6480464 Cyclic AMP results in increased activity of ESR1 protein CTD PMID:20360387 Esr1 Mouse 3,3',4,4',5-pentachlorobiphenyl affects binding ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16489053 Esr1 Mouse 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:37080397 Esr1 Mouse 3,3',4,4',5-pentachlorobiphenyl increases expression ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16489053 and PMID:26519613 Esr1 Mouse 3,3',4,4',5-pentachlorobiphenyl affects expression ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:21703328 Esr1 Mouse 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16489053 and PMID:26519613 Esr1 Mouse 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16972788 and PMID:26519613 Esr1 Mouse 3,3',4,4'-tetrachlorobiphenyl increases expression ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:26519613 Esr1 Mouse 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:19467301 Esr1 Mouse 3,3',4,4'-tetrachlorobiphenyl affects binding ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16293362 Esr1 Mouse 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of ESR1 protein CTD PMID:12505372 Esr1 Mouse 3,3',5,5'-tetrabromobisphenol A affects expression ISO Esr1 (Rattus norvegicus) 6480464 tetrabromobisphenol A affects the expression of ESR1 mRNA CTD PMID:26988606 Esr1 Mouse 3,3',5,5'-tetrabromobisphenol A multiple interactions ISO ESR1 (Homo sapiens) 6480464 tetrabromobisphenol A binds to and results in increased activity of ESR1 protein and tetrabromobisphenol A inhibits the reaction [Coumestrol binds to ESR1 protein modified form] CTD PMID:23398518 and PMID:29152682 Esr1 Mouse 3,3',5,5'-tetrabromobisphenol A affects binding ISO ESR1 (Homo sapiens) 6480464 tetrabromobisphenol A binds to ESR1 protein CTD PMID:11693576 and PMID:12753421 Esr1 Mouse 3,3',5-triiodo-L-thyronine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Tamoxifen inhibits the reaction [Triiodothyronine results in decreased expression of ESR1 mRNA] and Triiodothyronine binds to and results in increased activity of ESR1 protein CTD PMID:19942988 and PMID:33049310 Esr1 Mouse 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of ESR1 mRNA CTD PMID:34571837 Esr1 Mouse 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Triiodothyronine] results in increased expression of ESR1 mRNA and Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of ESR1 mRNA] CTD PMID:34571837 Esr1 Mouse 3,3',5-triiodo-L-thyronine decreases expression ISO ESR1 (Homo sapiens) 6480464 Triiodothyronine results in decreased expression of ESR1 mRNA CTD PMID:19942988 Esr1 Mouse 3,3'-diindolylmethane multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16972788 and PMID:23583297 Esr1 Mouse 3,3'-diindolylmethane decreases expression ISO ESR1 (Homo sapiens) 6480464 3 and 3'-diindolylmethane results in decreased expression of ESR1 CTD PMID:19223575 Esr1 Mouse 3,3'-Dimethylbenzidine multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-tolidine binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol increases activity ISO ESR1 (Homo sapiens) 6480464 fluorotelomer alcohols results in increased activity of ESR1 protein CTD PMID:17603182 Esr1 Mouse 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol multiple interactions ISO ESR1 (Homo sapiens) 6480464 fluorotelomer alcohols promotes the reaction [ESR1 protein binds to NCOA2 protein] CTD PMID:17603182 Esr1 Mouse 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol increases expression ISO ESR1 (Homo sapiens) 6480464 fluorotelomer alcohols results in increased expression of ESR1 mRNA CTD PMID:16393665 Esr1 Mouse 3,5-di-tert-Butyl-4-hydroxybenzaldehyde multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 and 5-di-tert-butyl-4-hydroxybenzaldehyde binds to and results in decreased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse 3,6-diaminoacridine increases activity ISO ESR1 (Homo sapiens) 6480464 Proflavine results in increased activity of ESR1 protein CTD PMID:30818834 Esr1 Mouse 3,7-dihydropurine-6-thione increases expression ISO Esr1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of ESR1 mRNA CTD PMID:23358152 Esr1 Mouse 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid decreases activity ISO Esr1 (Rattus norvegicus) 6480464 3-(2 more ... CTD PMID:20410157 Esr1 Mouse 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 [Estradiol co-treated with bisindolylmaleimide I] results in increased expression of ESR1 mRNA CTD PMID:12927369 Esr1 Mouse 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione increases expression EXP 6480464 bisindolylmaleimide I results in increased expression of ESR1 protein CTD PMID:12927369 Esr1 Mouse 3-iodoprop-2-yn-1-yl butylcarbamate multiple interactions ISO ESR1 (Homo sapiens) 6480464 3-iodo-2-propynylbutylcarbamate binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR1 protein and [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ESR1 mRNA CTD PMID:26944108 and PMID:28849599 Esr1 Mouse 3-isobutyl-1-methyl-7H-xanthine increases activity ISO ESR1 (Homo sapiens) 6480464 1-Methyl-3-isobutylxanthine results in increased activity of ESR1 protein CTD PMID:28711546 Esr1 Mouse 3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one multiple interactions ISO ESR1 (Homo sapiens) 6480464 alpha-isomethylionone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 3-methylcholanthrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Methylcholanthrene results in increased expression of ESR1 mRNA] more ... CTD PMID:16489053 more ... Esr1 Mouse 3-methylcholanthrene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Methylcholanthrene results in decreased expression of ESR1 mRNA CTD PMID:29094188 Esr1 Mouse 3-methylcholanthrene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA] CTD PMID:29094188 Esr1 Mouse 3-methylcholanthrene increases expression ISO Esr1 (Rattus norvegicus) 6480464 Methylcholanthrene results in increased expression of ESR1 mRNA CTD PMID:23273579 Esr1 Mouse 3-methylcholanthrene decreases expression ISO ESR1 (Homo sapiens) 6480464 Methylcholanthrene results in decreased expression of ESR1 mRNA CTD PMID:20348232 Esr1 Mouse 3-methylcholanthrene increases expression ISO ESR1 (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of ESR1 mRNA CTD PMID:16489053 Esr1 Mouse 3-methylcholanthrene increases activity ISO ESR1 (Homo sapiens) 6480464 Methylcholanthrene results in increased activity of ESR1 protein CTD PMID:16257430 Esr1 Mouse 3-methylcholanthrene affects binding ISO ESR1 (Homo sapiens) 6480464 Methylcholanthrene binds to ESR1 protein CTD PMID:16489053 Esr1 Mouse 3-methylquinoline multiple interactions ISO ESR1 (Homo sapiens) 6480464 3-methylquinoline inhibits the reaction [Estradiol binds to ESR1 protein] and Hydralazine inhibits the reaction [3-methylquinoline results in increased activity of ESR1 protein] CTD PMID:30896932 Esr1 Mouse 3-methylquinoline increases activity ISO ESR1 (Homo sapiens) 6480464 3-methylquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse 3-phenoxybenzoic acid decreases activity ISO Esr1 (Rattus norvegicus) 6480464 3-phenoxybenzoic acid results in decreased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse 3-phenoxybenzoic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 3-phenoxybenzoic acid inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] CTD PMID:24388911 Esr1 Mouse 3-phenoxybenzoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 3-phenoxybenzoic acid inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] CTD PMID:24388911 Esr1 Mouse 4'-epidoxorubicin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Epirubicin binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse 4'-hydroxydiclofenac affects activity ISO ESR1 (Homo sapiens) 6480464 4'-hydroxydiclofenac affects the activity of ESR1 protein CTD PMID:29777833 Esr1 Mouse 4,4'-sulfonyldiphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ESR1 protein more ... CTD PMID:22507746 more ... Esr1 Mouse 4,4'-sulfonyldiphenol increases acetylation ISO ESR1 (Homo sapiens) 6480464 bisphenol S results in increased acetylation of ESR1 protein CTD PMID:37315367 Esr1 Mouse 4,4'-sulfonyldiphenol decreases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol S results in decreased expression of ESR1 mRNA and bisphenol S results in decreased expression of ESR1 protein CTD PMID:31995776 more ... Esr1 Mouse 4,4'-sulfonyldiphenol increases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol S results in increased expression of ESR1 protein CTD PMID:36565802 Esr1 Mouse 4,4'-sulfonyldiphenol increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 bisphenol S results in increased phosphorylation of ESR1 protein CTD PMID:32105160 Esr1 Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of ESR1 mRNA CTD PMID:30196065 more ... Esr1 Mouse 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bisphenol S results in decreased expression of ESR1 mRNA and bisphenol S results in decreased expression of ESR1 protein CTD PMID:29526645 and PMID:36310694 Esr1 Mouse 4,4'-sulfonyldiphenol affects binding ISO ESR1 (Homo sapiens) 6480464 bisphenol S binds to ESR1 protein CTD PMID:30143207 Esr1 Mouse 4,4'-sulfonyldiphenol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [1 and 3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole results in decreased activity of ESR1 protein] which results in increased susceptibility to bisphenol S CTD PMID:25723814 Esr1 Mouse 4,4'-sulfonyldiphenol increases activity ISO ESR1 (Homo sapiens) 6480464 bisphenol S metabolite results in increased activity of ESR1 protein and bisphenol S results in increased activity of ESR1 protein CTD PMID:23714657 more ... Esr1 Mouse 4,4'-thiodiphenol affects binding ISO ESR1 (Homo sapiens) 6480464 bis(4-oxyphenyl)sulfide binds to ESR1 protein CTD PMID:31836225 Esr1 Mouse 4,4'-thiodiphenol increases expression ISO ESR1 (Homo sapiens) 6480464 bis(4-oxyphenyl)sulfide results in increased expression of ESR1 protein CTD PMID:27880919 Esr1 Mouse 4,4'-thiodiphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:27880919 Esr1 Mouse 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fadrozole binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 4-Acetyl-6-tert-butyl-1,1-dimethylindane multiple interactions ISO ESR1 (Homo sapiens) 6480464 acetyl tert-butyl dimethylindan binds to and results in increased activity of ESR1 protein CTD PMID:17762842 Esr1 Mouse 4-chloro-3,5-dimethylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 chloroxylenol binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 4-ethylphenol affects localization EXP 6480464 4-ethylphenol affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse 4-ethylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-ethylphenol binds to ESR1 protein CTD PMID:12598185 and PMID:19913605 Esr1 Mouse 4-hexylbenzene-1,3-diol increases activity ISO ESR1 (Homo sapiens) 6480464 Hexylresorcinol results in increased activity of ESR1 protein CTD PMID:19063592 Esr1 Mouse 4-hydroxy-17beta-estradiol affects binding ISO ESR1 (Homo sapiens) 6480464 4-hydroxyestradiol binds to ESR1 protein CTD PMID:15993745 Esr1 Mouse 4-hydroxy-17beta-estradiol increases expression ISO ESR1 (Homo sapiens) 6480464 4-hydroxyestradiol results in increased expression of ESR1 protein CTD PMID:23685341 Esr1 Mouse 4-hydroxy-17beta-estradiol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] and [4-hydroxyestradiol results in increased activity of ESR1 protein] promotes the reaction [ESR1 protein binds to TFF1 promoter] CTD PMID:20540524 and PMID:9048584 Esr1 Mouse 4-Hydroxy-N-desmethyltamoxifen multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [[Tamoxifen co-treated with N-desmethyltamoxifen co-treated with afimoxifene] results in increased stability of ESR1 protein] CTD PMID:19244106 Esr1 Mouse 4-Hydroxy-N-desmethyltamoxifen increases degradation ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen results in increased degradation of ESR1 protein CTD PMID:19244106 Esr1 Mouse 4-Hydroxy-N-desmethyltamoxifen decreases expression ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen results in decreased expression of ESR1 mRNA and 4-hydroxy-N-desmethyltamoxifen results in decreased expression of ESR1 protein CTD PMID:19244106 Esr1 Mouse 4-Hydroxyazobenzene increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-hydroxyazobenzene results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse 4-Hydroxybenzophenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxybenzophenone binds to and results in increased activity of ESR1 protein and 4-hydroxybenzophenone inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:11354909 more ... Esr1 Mouse 4-Hydroxybenzophenone affects binding ISO ESR1 (Homo sapiens) 6480464 4-hydroxybenzophenone binds to ESR1 protein CTD PMID:11354909 Esr1 Mouse 4-Hydroxybenzophenone increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-hydroxybenzophenone results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of ESR1 mRNA CTD PMID:28973697 Esr1 Mouse 4-Hydroxytestosterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 4 and 17 beta-dihydroxy-4-androstene-3-one inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] CTD PMID:29702199 Esr1 Mouse 4-methylquinoline increases activity ISO ESR1 (Homo sapiens) 6480464 4-methylquinoline analog results in increased activity of ESR1 protein and 4-methylquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse 4-nitrophenol increases expression ISO Esr1 (Rattus norvegicus) 6480464 4-nitrophenol results in increased expression of ESR1 mRNA and 4-nitrophenol results in increased expression of ESR1 protein CTD PMID:24070737 and PMID:27172127 Esr1 Mouse 4-nitrophenol affects expression ISO Esr1 (Rattus norvegicus) 6480464 4-nitrophenol affects the expression of ESR1 protein CTD PMID:27172127 Esr1 Mouse 4-nonylphenol affects localization EXP 6480464 4-nonylphenol affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse 4-nonylphenol decreases expression EXP 6480464 4-nonylphenol analog results in decreased expression of ESR1 mRNA and 4-nonylphenol analog results in decreased expression of ESR1 protein CTD PMID:27086933 Esr1 Mouse 4-nonylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-nonylphenol binds to ESR1 protein CTD PMID:11518614 more ... Esr1 Mouse 4-nonylphenol multiple interactions EXP 6480464 4-nonylphenol inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] CTD PMID:22056370 Esr1 Mouse 4-nonylphenol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 4-nonylphenol results in decreased expression of ESR1 mRNA and 4-nonylphenol results in decreased expression of ESR1 protein CTD PMID:24388992 Esr1 Mouse 4-nonylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-nonylphenol results in increased activity of ESR1 protein CTD PMID:17174995 Esr1 Mouse 4-nonylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 4-nonylphenol results in increased activity of ESR1 protein and 4-nonylphenol results in increased activity of ESR1 protein mutant form CTD PMID:17141713 more ... Esr1 Mouse 4-nonylphenol decreases expression ISO ESR1 (Homo sapiens) 6480464 4-nonylphenol results in decreased expression of ESR1 mRNA CTD PMID:16393665 Esr1 Mouse 4-nonylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-nonylphenol binds to and results in increased activity of ESR1 protein more ... CTD PMID:11530281 more ... Esr1 Mouse 4-octylphenol affects localization EXP 6480464 4-octylphenol affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse 4-octylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [4-octylphenol co-treated with ESR1 protein] results in increased expression of LTF mRNA CTD PMID:21783566 Esr1 Mouse 4-octylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-octylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-octylphenol affects binding EXP 6480464 4-octylphenol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse 4-octylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-octylphenol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse 4-octylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 4-octylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-Propylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-propylphenol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse 4-Propylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-propylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-Propylphenol affects localization EXP 6480464 4-propylphenol affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse 4-Propylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 4-propylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-terpineol multiple interactions ISO ESR1 (Homo sapiens) 6480464 NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein] CTD PMID:31393563 Esr1 Mouse 4-terpineol increases activity ISO ESR1 (Homo sapiens) 6480464 terpinenol-4 results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse 4-tert-Butylcyclohexyl acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-tert-butylcyclohexyl acetate binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse 4-tert-butylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 butylphen results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-tert-butylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 butylphen binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse 4-tert-butylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 butylphen binds to ESR1 protein CTD PMID:12598185 and PMID:19913605 Esr1 Mouse 4-tert-butylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 butylphen results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse 4-tert-Octylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol binds to and results in increased activity of ESR1 protein more ... CTD PMID:10964929 more ... Esr1 Mouse 4-tert-Octylphenol affects binding ISO Esr1 (Rattus norvegicus) 6480464 4-tert-octylphenol binds to ESR1 protein CTD PMID:11086226 Esr1 Mouse 4-tert-Octylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse 4-tert-Octylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of ESR1 mRNA and 4-tert-octylphenol results in decreased expression of ESR1 protein CTD PMID:23557686 and PMID:30061528 Esr1 Mouse 4-tert-Octylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased activity of ESR1 protein mutant form CTD PMID:17141713 Esr1 Mouse 4-tert-Octylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol binds to ESR1 protein CTD PMID:10964929 more ... Esr1 Mouse 4-tert-Octylphenol affects binding EXP 6480464 4-tert-octylphenol binds to ESR1 protein CTD PMID:11162928 Esr1 Mouse 4-tert-Octylphenol multiple interactions EXP 6480464 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA] and Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of ESR1 mRNA] CTD PMID:23557686 and PMID:30061528 Esr1 Mouse 4-tert-Octylphenol increases expression ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased expression of ESR1 mRNA CTD PMID:12737316 Esr1 Mouse 4-vinylcyclohexene dioxide affects expression EXP 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of ESR1 mRNA CTD PMID:20829426 Esr1 Mouse 5-(hydroxymethyl)cytosine multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] and ESR1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 Esr1 Mouse 5-(hydroxymethyl)cytosine decreases abundance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:32105160 Esr1 Mouse 5-aza-2'-deoxycytidine increases expression ISO ESR1 (Homo sapiens) 6480464 Decitabine results in increased expression of ESR1 mRNA CTD PMID:18701604 more ... Esr1 Mouse 5-aza-2'-deoxycytidine decreases methylation ISO ESR1 (Homo sapiens) 6480464 Decitabine results in decreased methylation of ESR1 promoter CTD PMID:34534549 Esr1 Mouse 5-aza-2'-deoxycytidine multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Decitabine co-treated with TFAP2C protein] results in increased expression of ESR1 mRNA more ... CTD PMID:17533736 more ... Esr1 Mouse 5-aza-2'-deoxycytidine decreases stability ISO ESR1 (Homo sapiens) 6480464 Decitabine results in decreased stability of ESR1 mRNA CTD PMID:17891453 Esr1 Mouse 5-aza-2'-deoxycytidine decreases expression ISO ESR1 (Homo sapiens) 6480464 Decitabine results in decreased expression of ESR1 mRNA and Decitabine results in decreased expression of ESR1 protein CTD PMID:17891453 and PMID:19027819 Esr1 Mouse 5-azacytidine increases expression ISO ESR1 (Homo sapiens) 6480464 Azacitidine results in increased expression of ESR1 protein CTD PMID:22558281 Esr1 Mouse 5alpha-pregnane-3,20-dione increases expression ISO ESR1 (Homo sapiens) 6480464 5-alpha-Dihydroprogesterone results in increased expression of ESR1 mRNA CTD PMID:17683929 Esr1 Mouse 6-methylquinoline increases activity ISO ESR1 (Homo sapiens) 6480464 6-methylquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse 6-oxocampestanol increases expression ISO ESR1 (Homo sapiens) 6480464 6-oxocampestanol results in increased expression of ESR1 protein CTD PMID:32001316 Esr1 Mouse 6-prenylnaringenin multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein] more ... CTD PMID:32986415 Esr1 Mouse 6-prenylnaringenin decreases expression ISO ESR1 (Homo sapiens) 6480464 6-prenylnaringenin results in decreased expression of ESR1 protein CTD PMID:32986415 Esr1 Mouse 6alpha-methylprednisolone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Methylprednisolone binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse 7,12-dimethyltetraphene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:16891317 Esr1 Mouse 7,12-dimethyltetraphene multiple interactions ISO ESR1 (Homo sapiens) 6480464 9 more ... CTD PMID:33049310 Esr1 Mouse 7,12-dimethyltetraphene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Estradiol co-treated with 9 more ... CTD PMID:16891317 Esr1 Mouse 8-methylquinoline multiple interactions ISO ESR1 (Homo sapiens) 6480464 8-methylquinoline inhibits the reaction [Estradiol binds to ESR1 protein] and Hydralazine inhibits the reaction [8-methylquinoline results in increased activity of ESR1 protein] CTD PMID:30896932 Esr1 Mouse 8-methylquinoline increases activity ISO ESR1 (Homo sapiens) 6480464 8-methylquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse 9-cis-retinoic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Melatonin promotes the reaction [Alitretinoin results in decreased expression of ESR1 mRNA] CTD PMID:16051031 Esr1 Mouse 9-cis-retinoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 Alitretinoin inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:19340624 Esr1 Mouse 9-cis-retinoic acid decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Alitretinoin results in decreased expression of ESR1 mRNA CTD PMID:16051031 Esr1 Mouse 9-phenanthrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 9-phenanthrol binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse acetamide decreases expression ISO Esr1 (Rattus norvegicus) 6480464 acetamide results in decreased expression of ESR1 mRNA CTD PMID:31881176 Esr1 Mouse acetochlor multiple interactions ISO ESR1 (Homo sapiens) 6480464 acetochlor binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse acetylcholine multiple interactions EXP 6480464 ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Acetylcholine] and ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine co-treated with Acetylcholine] CTD PMID:17158209 Esr1 Mouse acrolein affects expression ISO ESR1 (Homo sapiens) 6480464 Acrolein affects the expression of ESR1 mRNA CTD PMID:19527780 Esr1 Mouse adenosine increases expression EXP 6480464 Adenosine results in increased expression of ESR1 protein CTD PMID:29360751 Esr1 Mouse adenosine increases expression ISO ESR1 (Homo sapiens) 6480464 Adenosine results in increased expression of ESR1 protein CTD PMID:29360751 Esr1 Mouse afimoxifene multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [[Tamoxifen co-treated with N-desmethyltamoxifen co-treated with afimoxifene] results in increased stability of ESR1 protein] more ... CTD PMID:10614829 more ... Esr1 Mouse afimoxifene increases activity ISO ESR1 (Homo sapiens) 6480464 afimoxifene results in increased activity of ESR1 protein CTD PMID:28704378 Esr1 Mouse afimoxifene affects folding ISO ESR1 (Homo sapiens) 6480464 afimoxifene affects the folding of ESR1 protein CTD PMID:18678925 Esr1 Mouse afimoxifene affects binding EXP 6480464 afimoxifene binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse afimoxifene decreases activity ISO ESR1 (Homo sapiens) 6480464 afimoxifene results in decreased activity of ESR1 protein CTD PMID:14754635 more ... Esr1 Mouse afimoxifene multiple interactions EXP 6480464 afimoxifene binds to and affects the folding of ESR1 protein mutant form and ESR1 protein promotes the reaction [afimoxifene results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 and PMID:27721470 Esr1 Mouse afimoxifene increases expression ISO ESR1 (Homo sapiens) 6480464 afimoxifene results in increased expression of ESR1 protein CTD PMID:19244106 Esr1 Mouse afimoxifene affects binding ISO ESR1 (Homo sapiens) 6480464 [afimoxifene binds to ESR1 protein] which binds to TFF1 protein and afimoxifene binds to ESR1 protein CTD PMID:10397250 more ... Esr1 Mouse aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of ESR1 mRNA and Aflatoxin B1 results in decreased expression of ESR1 protein CTD PMID:19770486 and PMID:29274131 Esr1 Mouse aflatoxin B1 increases methylation ISO ESR1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ESR1 intron CTD PMID:30157460 Esr1 Mouse aflatoxin B1 decreases expression ISO ESR1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of ESR1 mRNA CTD PMID:28965971 Esr1 Mouse Aflatoxin B2 alpha increases methylation ISO ESR1 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of ESR1 intron CTD PMID:30157460 Esr1 Mouse alachlor affects binding ISO ESR1 (Homo sapiens) 6480464 alachlor binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse alachlor multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein] and alachlor inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 and PMID:9168004 Esr1 Mouse aldehydo-D-glucose increases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse aldehydo-D-glucose increases abundance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased abundance of Glucose CTD PMID:31520823 Esr1 Mouse aldehydo-D-glucose multiple interactions ISO ESR1 (Homo sapiens) 6480464 Endosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose] CTD PMID:31520823 Esr1 Mouse aldehydo-D-glucose increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of ESR1 protein CTD PMID:23690508 Esr1 Mouse aldehydo-D-glucose multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA more ... CTD PMID:18426865 and PMID:37606869 Esr1 Mouse aldehydo-D-glucose decreases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in decreased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse aldicarb multiple interactions ISO ESR1 (Homo sapiens) 6480464 Aldicarb inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 Esr1 Mouse aldrin affects binding ISO ESR1 (Homo sapiens) 6480464 Aldrin binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse aldrin increases activity ISO ESR1 (Homo sapiens) 6480464 Aldrin results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26022396 Esr1 Mouse aldrin increases expression ISO ESR1 (Homo sapiens) 6480464 Aldrin results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse aldrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA and Aldrin inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 and PMID:21295777 Esr1 Mouse alizarin multiple interactions ISO ESR1 (Homo sapiens) 6480464 alizarin binds to and results in increased activity of ESR1 protein CTD PMID:20707409 Esr1 Mouse all-trans-phytoene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 Esr1 Mouse all-trans-phytofluene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 Esr1 Mouse all-trans-retinoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] CTD PMID:16730657 Esr1 Mouse all-trans-retinoic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 mRNA] more ... CTD PMID:17161848 and PMID:21964460 Esr1 Mouse all-trans-retinoic acid affects expression ISO Esr1 (Rattus norvegicus) 6480464 Tretinoin affects the expression of ESR1 mRNA CTD PMID:11751013 Esr1 Mouse all-trans-retinoic acid increases expression ISO ESR1 (Homo sapiens) 6480464 Tretinoin results in increased expression of ESR1 protein CTD PMID:17387344 Esr1 Mouse all-trans-retinol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Vitamin A inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:19340624 Esr1 Mouse alpha-hexachlorocyclohexane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 alpha-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 Esr1 Mouse alpha-hexachlorocyclohexane increases activity ISO ESR1 (Homo sapiens) 6480464 alpha-hexachlorocyclohexane results in increased activity of ESR1 protein CTD PMID:26022396 Esr1 Mouse alpha-mangostin multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [mangostin results in increased activity of CASP7 protein] CTD PMID:24480042 Esr1 Mouse alpha-mangostin decreases expression ISO ESR1 (Homo sapiens) 6480464 mangostin results in decreased expression of ESR1 protein CTD PMID:24480042 Esr1 Mouse alpha-mangostin affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to mangostin CTD PMID:24480042 Esr1 Mouse alpha-Methylstyrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 alpha-methylstyrol binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse alpha-naphthoflavone affects binding ISO ESR1 (Homo sapiens) 6480464 [alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein CTD PMID:10620335 Esr1 Mouse alpha-naphthoflavone multiple interactions ISO ESR1 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Estradiol binds to ESR1 protein]] more ... CTD PMID:15253042 and PMID:35181438 Esr1 Mouse alpha-naphthoflavone multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA and alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA] CTD PMID:22975028 and PMID:29094188 Esr1 Mouse alpha-terpineol multiple interactions ISO ESR1 (Homo sapiens) 6480464 alpha-terpineol binds to and results in increased activity of ESR1 protein and NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:27633901 and PMID:31393563 Esr1 Mouse alpha-terpineol increases activity ISO ESR1 (Homo sapiens) 6480464 alpha-terpineol results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse alpha-Zearalanol affects binding ISO ESR1 (Homo sapiens) 6480464 Zeranol binds to ESR1 protein CTD PMID:19913605 and PMID:30742918 Esr1 Mouse alpha-Zearalanol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Zeranol co-treated with butylbenzyl phthalate] affects the expression of ESR1 protein CTD PMID:35163327 Esr1 Mouse alpha-Zearalanol increases activity ISO ESR1 (Homo sapiens) 6480464 Zeranol results in increased activity of ESR1 protein CTD PMID:11331656 Esr1 Mouse alpha-Zearalanol affects binding EXP 6480464 Zeranol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse alpha-Zearalanol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Zeranol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse aluminium atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 [aluminum chlorhydrate results in increased abundance of Aluminum] inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein] more ... CTD PMID:31945389 Esr1 Mouse aluminium(0) multiple interactions ISO ESR1 (Homo sapiens) 6480464 [aluminum chlorhydrate results in increased abundance of Aluminum] inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein] more ... CTD PMID:31945389 Esr1 Mouse amsacrine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Amsacrine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse androgen antagonist multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Pesticides co-treated with Phthalic Acids co-treated with Androgen Antagonists] results in increased expression of ESR1 mRNA CTD PMID:29945228 Esr1 Mouse androst-4-ene-3,17-dione multiple interactions ISO ESR1 (Homo sapiens) 6480464 Androstenedione binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse androst-5-ene-3beta,17beta-diol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Androstenediol inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] CTD PMID:9048584 Esr1 Mouse androstane-3,17-diol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Androstane-3 more ... CTD PMID:17003281 Esr1 Mouse anethole affects binding ISO Esr1 (Rattus norvegicus) 6480464 anethole analog binds to ESR1 protein CTD PMID:27420082 Esr1 Mouse anethole affects binding ISO ESR1 (Homo sapiens) 6480464 anethole metabolite binds to ESR1 protein CTD PMID:12818366 Esr1 Mouse anethole multiple interactions ISO ESR1 (Homo sapiens) 6480464 anethole metabolite inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12818366 Esr1 Mouse anilines multiple interactions ISO ESR1 (Homo sapiens) 6480464 Aniline Compounds binds to and results in decreased activity of ESR1 protein and Aniline Compounds binds to and results in increased activity of ESR1 protein CTD PMID:12820998 and PMID:25123791 Esr1 Mouse anthracene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein and AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein] CTD PMID:30980910 Esr1 Mouse antirheumatic drug decreases expression ISO ESR1 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of ESR1 mRNA CTD PMID:24449571 Esr1 Mouse apigenin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Apigenin binds to and results in increased activity of ESR1 protein more ... CTD PMID:14579009 more ... Esr1 Mouse apigenin increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 Apigenin results in increased phosphorylation of ESR1 protein CTD PMID:17323972 Esr1 Mouse apigenin increases activity ISO ESR1 (Homo sapiens) 6480464 Apigenin results in increased activity of ESR1 protein CTD PMID:16118406 more ... Esr1 Mouse apigenin decreases expression ISO ESR1 (Homo sapiens) 6480464 Apigenin results in decreased expression of ESR1 protein CTD PMID:16541309 Esr1 Mouse apigenin affects binding ISO ESR1 (Homo sapiens) 6480464 Apigenin binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of ESR1 CTD PMID:21664404 Esr1 Mouse Aroclor 1254 affects expression ISO Esr1 (Rattus norvegicus) 6480464 Chlorodiphenyl (54% Chlorine) affects the expression of ESR1 mRNA CTD PMID:34858468 Esr1 Mouse Aroclor 1254 multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Chlorodiphenyl (54% Chlorine)] results in decreased expression of ESR1 mRNA CTD PMID:23804495 Esr1 Mouse Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ESR1 protein CTD PMID:24216299 Esr1 Mouse arsane decreases methylation EXP 6480464 Arsenic results in decreased methylation of ESR1 promoter CTD PMID:15026472 Esr1 Mouse arsane multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of ESR1 mRNA CTD PMID:35747940 Esr1 Mouse arsane decreases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic results in decreased expression of ESR1 mRNA and Arsenic results in decreased expression of ESR1 protein CTD PMID:33047385 Esr1 Mouse arsane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 4 more ... CTD PMID:32402895 and PMID:35993674 Esr1 Mouse arsane increases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic results in increased expression of ESR1 mRNA CTD PMID:17306315 Esr1 Mouse arsane increases expression EXP 6480464 Arsenic results in increased expression of ESR1 mRNA and Arsenic results in increased expression of ESR1 protein CTD PMID:15026472 and PMID:19450653 Esr1 Mouse arsenic atom decreases methylation EXP 6480464 Arsenic results in decreased methylation of ESR1 promoter CTD PMID:15026472 Esr1 Mouse arsenic atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of ESR1 mRNA CTD PMID:35747940 Esr1 Mouse arsenic atom decreases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic results in decreased expression of ESR1 mRNA and Arsenic results in decreased expression of ESR1 protein CTD PMID:33047385 Esr1 Mouse arsenic atom multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 4 more ... CTD PMID:32402895 and PMID:35993674 Esr1 Mouse arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of ESR1 mRNA and Arsenic results in increased expression of ESR1 protein CTD PMID:15026472 and PMID:19450653 Esr1 Mouse arsenic atom increases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic results in increased expression of ESR1 mRNA CTD PMID:17306315 Esr1 Mouse arsenite(3-) affects binding ISO ESR1 (Homo sapiens) 6480464 arsenite binds to ESR1 protein CTD PMID:15963345 Esr1 Mouse arsenite(3-) increases expression ISO ESR1 (Homo sapiens) 6480464 arsenite results in increased expression of ESR1 mRNA CTD PMID:31646340 Esr1 Mouse arsenite(3-) increases expression ISO Esr1 (Rattus norvegicus) 6480464 arsenite results in increased expression of ESR1 mRNA CTD PMID:25543096 Esr1 Mouse arsenite(3-) increases methylation ISO ESR1 (Homo sapiens) 6480464 arsenite results in increased methylation of ESR1 promoter CTD PMID:23974009 Esr1 Mouse arsenite(3-) multiple interactions ISO ESR1 (Homo sapiens) 6480464 arsenite inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:11014213 Esr1 Mouse arsenite(3-) decreases expression ISO ESR1 (Homo sapiens) 6480464 arsenite results in decreased expression of ESR1 mRNA and arsenite results in decreased expression of ESR1 protein CTD PMID:11014213 Esr1 Mouse arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of ESR1 mRNA CTD PMID:18991936 Esr1 Mouse arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of ESR1 protein CTD PMID:34050381 Esr1 Mouse arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ESR1 mRNA and Arsenic Trioxide results in increased expression of ESR1 protein CTD PMID:15073043 and PMID:23159075 Esr1 Mouse arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased methylation of ESR1 gene more ... CTD PMID:23159075 Esr1 Mouse arsenous acid decreases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of ESR1 mRNA and Arsenic Trioxide results in decreased expression of ESR1 protein CTD PMID:12014631 more ... Esr1 Mouse arsenous acid decreases methylation EXP 6480464 Arsenic Trioxide results in decreased methylation of ESR1 promoter CTD PMID:15073043 Esr1 Mouse arsenous acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Arsenic Trioxide results in decreased methylation of ESR1 promoter] which results in increased expression of ESR1 mRNA more ... CTD PMID:15283693 more ... Esr1 Mouse arsenous acid decreases methylation ISO ESR1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased methylation of ESR1 gene and Arsenic Trioxide results in decreased methylation of ESR1 promoter CTD PMID:21687957 and PMID:23159075 Esr1 Mouse arsenous acid increases expression ISO ESR1 (Homo sapiens) 6480464 [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA more ... CTD PMID:20458559 more ... Esr1 Mouse artesunate multiple interactions ISO ESR1 (Homo sapiens) 6480464 artesunate binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse atrazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Atrazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein] more ... CTD PMID:14579009 more ... Esr1 Mouse atrazine increases expression EXP 6480464 Atrazine results in increased expression of ESR1 protein CTD PMID:33766575 Esr1 Mouse atrazine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Atrazine results in increased expression of ESR1 mRNA and Atrazine results in increased expression of ESR1 protein CTD PMID:23200735 and PMID:34600026 Esr1 Mouse atrazine decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of ESR1 mRNA CTD PMID:22285353 Esr1 Mouse atrazine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Atrazine inhibits the reaction [Bucladesine results in increased expression of ESR1 mRNA] more ... CTD PMID:15056801 more ... Esr1 Mouse atrazine affects binding ISO ESR1 (Homo sapiens) 6480464 Atrazine binds to ESR1 protein CTD PMID:14579009 and PMID:8858116 Esr1 Mouse avobenzone multiple interactions ISO ESR1 (Homo sapiens) 6480464 avobenzone binds to and results in increased activity of ESR1 protein CTD PMID:15537743 Esr1 Mouse azadirachtin A increases expression EXP 6480464 azadirachtin results in increased expression of ESR1 mRNA and azadirachtin results in increased expression of ESR1 protein CTD PMID:31225646 Esr1 Mouse azadirachtin A affects binding ISO ESR1 (Homo sapiens) 6480464 azadirachtin binds to ESR1 protein CTD PMID:31225646 Esr1 Mouse azadirachtin A multiple interactions EXP 6480464 1 more ... CTD PMID:31225646 Esr1 Mouse azinphos-methyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 Azinphosmethyl binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse baicalein multiple interactions ISO ESR1 (Homo sapiens) 6480464 baicalein inhibits the reaction [Cholesterol and LDL analog results in decreased expression of ESR1 mRNA] CTD PMID:38230788 Esr1 Mouse baicalein affects binding ISO ESR1 (Homo sapiens) 6480464 baicalein binds to ESR1 protein CTD PMID:38230788 Esr1 Mouse bazedoxifene affects binding ISO ESR1 (Homo sapiens) 6480464 bazedoxifene binds to ESR1 protein CTD PMID:15961563 Esr1 Mouse bazedoxifene multiple interactions EXP 6480464 bazedoxifene affects the reaction [Oxygen deficiency affects the expression of ESR1 protein alternative form] and bazedoxifene affects the reaction [Oxygen deficiency affects the expression of ESR1 protein] CTD PMID:28859903 Esr1 Mouse bazedoxifene increases activity ISO ESR1 (Homo sapiens) 6480464 bazedoxifene results in increased activity of ESR1 protein CTD PMID:28704378 Esr1 Mouse bendiocarb multiple interactions ISO ESR1 (Homo sapiens) 6480464 bendiocarb inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 Esr1 Mouse benidipine decreases activity ISO ESR1 (Homo sapiens) 6480464 benidipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse benomyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 Benomyl binds to and results in increased activity of ESR1 protein and Benomyl inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 and PMID:16626760 Esr1 Mouse benomyl affects binding ISO ESR1 (Homo sapiens) 6480464 Benomyl binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse benzamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to CTSD promoter]] more ... CTD PMID:17157789 Esr1 Mouse benzo[a]pyrene affects activity ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the activity of ESR1 protein CTD PMID:20624995 Esr1 Mouse benzo[a]pyrene decreases methylation ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of ESR1 3' UTR CTD PMID:27901495 Esr1 Mouse benzo[a]pyrene affects methylation ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ESR1 5' UTR more ... CTD PMID:27901495 and PMID:30157460 Esr1 Mouse benzo[a]pyrene increases activity ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased activity of ESR1 protein CTD PMID:26022396 and PMID:28728110 Esr1 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ESR1 mRNA and Benzo(a)pyrene results in decreased expression of ESR1 protein CTD PMID:19770486 and PMID:26149760 Esr1 Mouse benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene inhibits the reaction [NR2E3 protein binds to ESR1 promoter] and Benzo(a)pyrene promotes the reaction [KDM1A protein binds to ESR1 promoter] CTD PMID:26149760 Esr1 Mouse benzo[a]pyrene decreases expression ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ESR1 mRNA and Benzo(a)pyrene results in decreased expression of ESR1 protein CTD PMID:26149760 Esr1 Mouse benzo[a]pyrene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of ESR1 mRNA and Benzo(a)pyrene results in decreased expression of ESR1 protein CTD PMID:17583486 more ... Esr1 Mouse benzo[a]pyrene decreases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in decreased susceptibility to Benzo(a)pyrene CTD PMID:21920623 Esr1 Mouse benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ESR1 mRNA CTD PMID:22228805 Esr1 Mouse benzo[a]pyrene increases expression ISO ESR1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of ESR1 mRNA CTD PMID:11922773 and PMID:22316170 Esr1 Mouse benzo[a]pyrene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Benzo(a)pyrene affects the reaction [Ethinyl Estradiol results in decreased expression of ESR1 protein] CTD PMID:17583486 Esr1 Mouse benzo[a]pyrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with chrysene] results in increased expression of ESR1 mRNA more ... CTD PMID:11922773 more ... Esr1 Mouse benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of ESR1 protein CTD PMID:21392559 Esr1 Mouse benzo[b]fluoranthene increases activity ISO ESR1 (Homo sapiens) 6480464 benzo(b)fluoranthene results in increased activity of ESR1 protein CTD PMID:28728110 Esr1 Mouse benzo[d]isothiazol-3-one multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 and 2-benzisothiazoline-3-one inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:14702633 Esr1 Mouse benzo[d]isothiazol-3-one decreases activity ISO ESR1 (Homo sapiens) 6480464 1 and 2-benzisothiazoline-3-one results in decreased activity of ESR1 protein CTD PMID:14702633 Esr1 Mouse benzo[e]pyrene affects methylation ISO ESR1 (Homo sapiens) 6480464 benzo(e)pyrene affects the methylation of ESR1 intron CTD PMID:30157460 Esr1 Mouse Benzo[k]fluoranthene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 benzo(k)fluoranthene results in decreased expression of ESR1 protein CTD PMID:18634860 and PMID:21783948 Esr1 Mouse benzoates increases activity ISO ESR1 (Homo sapiens) 6480464 Benzoates results in increased activity of ESR1 protein CTD PMID:16756374 Esr1 Mouse benzophenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzophenone binds to and results in increased activity of ESR1 protein CTD PMID:16079615 and PMID:27633901 Esr1 Mouse benzophenones increases activity ISO Esr1 (Rattus norvegicus) 6480464 Benzophenones results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse benzothiophene multiple interactions EXP 6480464 benzothiophene analog binds to and results in increased activity of ESR1 protein CTD PMID:15713417 Esr1 Mouse Benzoyl peroxide multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Benzoyl Peroxide binds to and results in decreased activity of ESR1 protein CTD PMID:15348454 Esr1 Mouse benzyl benzoate multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyl benzoate inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:19338011 Esr1 Mouse Benzyl parahydroxybenzoate multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzylparaben binds to and results in increased activity of ESR1 protein CTD PMID:23220609 and PMID:23567241 Esr1 Mouse Benzyl salicylate increases activity ISO ESR1 (Homo sapiens) 6480464 benzyl salicylate results in increased activity of ESR1 protein CTD PMID:22197706 Esr1 Mouse Benzyl salicylate multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyl salicylate inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:19338011 Esr1 Mouse berberine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Berberine inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse beryllium atom increases methylation ISO Esr1 (Rattus norvegicus) 6480464 Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 Esr1 Mouse beryllium dihydride increases methylation ISO Esr1 (Rattus norvegicus) 6480464 Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 Esr1 Mouse beryllium(0) increases methylation ISO Esr1 (Rattus norvegicus) 6480464 Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 Esr1 Mouse beta-carotene multiple interactions ISO ESR1 (Homo sapiens) 6480464 beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] more ... CTD PMID:17051425 and PMID:19340624 Esr1 Mouse beta-hexachlorocyclohexane decreases expression ISO ESR1 (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA and beta-hexachlorocyclohexane results in decreased expression of ESR1 protein CTD PMID:12948864 and PMID:20206645 Esr1 Mouse beta-hexachlorocyclohexane increases expression ISO ESR1 (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse beta-hexachlorocyclohexane multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA] and fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA] CTD PMID:20206645 Esr1 Mouse beta-hexachlorocyclohexane increases expression EXP 6480464 beta-hexachlorocyclohexane results in increased expression of ESR1 protein CTD PMID:15541753 Esr1 Mouse beta-hexachlorocyclohexane increases activity ISO ESR1 (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26022396 Esr1 Mouse beta-hexachlorocyclohexane multiple interactions EXP 6480464 [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of ESR1 mRNA and beta-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:16758953 and PMID:21278053 Esr1 Mouse beta-naphthoflavone decreases expression ISO Esr1 (Rattus norvegicus) 6480464 beta-Naphthoflavone results in decreased expression of ESR1 mRNA CTD PMID:20607812 Esr1 Mouse beta-naphthoflavone affects binding ISO ESR1 (Homo sapiens) 6480464 [beta-Naphthoflavone binds to AHR protein] which binds to ESR1 protein CTD PMID:10620335 Esr1 Mouse beta-naphthoflavone multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA CTD PMID:22975028 Esr1 Mouse beta-tocopherol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA] and [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 Esr1 Mouse beta-Zearalanol increases activity ISO ESR1 (Homo sapiens) 6480464 taleranol results in increased activity of ESR1 protein CTD PMID:11331656 and PMID:25455890 Esr1 Mouse bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of ESR1 mRNA CTD PMID:17849452 Esr1 Mouse bicalutamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 bicalutamide binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse bifenthrin decreases expression ISO ESR1 (Homo sapiens) 6480464 bifenthrin results in decreased expression of ESR1 mRNA CTD PMID:20097460 Esr1 Mouse bifenthrin affects binding ISO ESR1 (Homo sapiens) 6480464 bifenthrin binds to ESR1 protein CTD PMID:32278787 Esr1 Mouse bifenthrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 bifenthrin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse biochanin A multiple interactions ISO ESR1 (Homo sapiens) 6480464 biochanin A binds to and results in increased activity of ESR1 protein and biochanin A inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 more ... Esr1 Mouse biochanin A multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Fulvestrant co-treated with biochanin A] results in decreased expression of ESR1 protein and [Fulvestrant co-treated with biochanin A] results in increased expression of ESR1 mRNA CTD PMID:34848279 Esr1 Mouse biochanin A decreases expression ISO Esr1 (Rattus norvegicus) 6480464 biochanin A results in decreased expression of ESR1 protein CTD PMID:34848279 Esr1 Mouse biochanin A affects binding ISO ESR1 (Homo sapiens) 6480464 biochanin A binds to ESR1 protein CTD PMID:12598185 more ... Esr1 Mouse biphenyl decreases activity ISO ESR1 (Homo sapiens) 6480464 biphenyl results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse biphenyl-2-ol decreases expression ISO ESR1 (Homo sapiens) 6480464 2-phenylphenol results in decreased expression of ESR1 mRNA CTD PMID:12822488 Esr1 Mouse biphenyl-2-ol affects binding ISO ESR1 (Homo sapiens) 6480464 2-phenylphenol binds to ESR1 protein CTD PMID:12598185 Esr1 Mouse biphenyl-2-ol increases expression ISO ESR1 (Homo sapiens) 6480464 2-phenylphenol results in increased expression of ESR1 mRNA CTD PMID:12737316 Esr1 Mouse biphenyl-4,4'-diol affects binding ISO ESR1 (Homo sapiens) 6480464 4 and 4'-dihydroxybiphenyl binds to ESR1 protein CTD PMID:12161000 and PMID:12753421 Esr1 Mouse biphenyl-4-ol increases expression ISO ESR1 (Homo sapiens) 6480464 4-phenylphenol results in increased expression of ESR1 mRNA CTD PMID:12737316 Esr1 Mouse biphenyl-4-ol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-phenylphenol binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse biphenyl-4-ol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-phenylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse biphenyl-4-ol increases activity ISO ESR1 (Homo sapiens) 6480464 4-phenylphenol results in increased activity of ESR1 protein CTD PMID:18028983 Esr1 Mouse biphenyl-4-ol affects binding ISO ESR1 (Homo sapiens) 6480464 4-phenylphenol binds to ESR1 protein CTD PMID:12753421 and PMID:31836225 Esr1 Mouse bis(2-ethylhexyl) phthalate increases activity ISO ESR1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased activity of ESR1 protein CTD PMID:16756374 Esr1 Mouse bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of ESR1 mRNA and Diethylhexyl Phthalate results in increased expression of ESR1 protein CTD PMID:34718101 and PMID:35550907 Esr1 Mouse bis(2-ethylhexyl) phthalate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased expression of ESR1 mRNA and Diethylhexyl Phthalate results in decreased expression of ESR1 protein CTD PMID:28871463 and PMID:36435455 Esr1 Mouse bis(2-ethylhexyl) phthalate decreases expression ISO ESR1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of ESR1 mRNA CTD PMID:30851587 Esr1 Mouse bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of ESR1 and Diethylhexyl Phthalate results in decreased expression of ESR1 mRNA CTD PMID:24811840 and PMID:32619501 Esr1 Mouse bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein more ... CTD PMID:23756648 more ... Esr1 Mouse bis(2-ethylhexyl) phthalate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA more ... CTD PMID:25031359 more ... Esr1 Mouse bis(2-ethylhexyl) phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of 2-ethyl-5-carboxypentyl phthalate] which results in decreased expression of ESR1 protein more ... CTD PMID:15840436 more ... Esr1 Mouse bisphenol A multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:10964929 more ... Esr1 Mouse bisphenol A increases response to substance EXP 6480464 ESR1 protein results in increased susceptibility to bisphenol A CTD PMID:37855322 Esr1 Mouse bisphenol A increases acetylation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in increased acetylation of ESR1 protein CTD PMID:37315367 Esr1 Mouse bisphenol A decreases methylation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of ESR1 gene and bisphenol A results in decreased methylation of ESR1 promoter CTD PMID:31601247 more ... Esr1 Mouse bisphenol A increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A results in increased phosphorylation of ESR1 protein CTD PMID:32429515 Esr1 Mouse bisphenol A affects methylation ISO ESR1 (Homo sapiens) 6480464 bisphenol A affects the methylation of ESR1 promoter CTD PMID:29643374 Esr1 Mouse bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of ESR1 exon and bisphenol A results in increased methylation of ESR1 promoter CTD PMID:29161229 and PMID:31463084 Esr1 Mouse bisphenol A increases methylation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in increased methylation of ESR1 gene and bisphenol A results in increased methylation of ESR1 promoter CTD PMID:27271280 and PMID:32466334 Esr1 Mouse bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of ESR1 promoter CTD PMID:27334623 Esr1 Mouse bisphenol A increases activity ISO ESR1 (Homo sapiens) 6480464 bisphenol A analog results in increased activity of ESR1 protein more ... CTD PMID:11145352 more ... Esr1 Mouse bisphenol A decreases activity ISO ESR1 (Homo sapiens) 6480464 bisphenol A metabolite results in decreased activity of ESR1 protein and bisphenol A results in decreased activity of ESR1 protein CTD PMID:15116845 Esr1 Mouse bisphenol A increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of ESR1 protein CTD PMID:25534675 more ... Esr1 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ESR1 mRNA and bisphenol A results in increased expression of ESR1 protein CTD PMID:12505546 more ... Esr1 Mouse bisphenol A decreases expression ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A analog results in decreased expression of ESR1 mRNA more ... CTD PMID:11896564 more ... Esr1 Mouse bisphenol A increases activity EXP 6480464 bisphenol A results in increased activity of ESR1 protein CTD PMID:18446233 more ... Esr1 Mouse bisphenol A decreases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol A analog results in decreased expression of ESR1 mRNA more ... CTD PMID:12753421 more ... Esr1 Mouse bisphenol A increases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in increased expression of ESR1 mRNA and bisphenol A results in increased expression of ESR1 protein CTD PMID:12737316 more ... Esr1 Mouse bisphenol A increases expression ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of ESR1 more ... CTD PMID:11108262 more ... Esr1 Mouse bisphenol A affects localization ISO ESR1 (Homo sapiens) 6480464 bisphenol A affects the localization of ESR1 protein CTD PMID:20678512 and PMID:23562765 Esr1 Mouse bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of ESR1 protein CTD PMID:21813366 more ... Esr1 Mouse bisphenol A decreases degradation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in decreased degradation of ESR1 protein CTD PMID:14702340 Esr1 Mouse bisphenol A increases degradation ISO ESR1 (Homo sapiens) 6480464 bisphenol A results in increased degradation of ESR1 protein CTD PMID:14702340 Esr1 Mouse bisphenol A affects binding ISO ESR1 (Homo sapiens) 6480464 bisphenol A analog binds to ESR1 protein more ... CTD PMID:10964929 more ... Esr1 Mouse bisphenol A increases activity ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A results in increased activity of ESR1 protein CTD PMID:11750080 more ... Esr1 Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ESR1 mRNA and bisphenol A results in decreased expression of ESR1 protein CTD PMID:12927369 more ... Esr1 Mouse bisphenol A affects binding EXP 6480464 bisphenol A binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse bisphenol A affects expression ISO ESR1 (Homo sapiens) 6480464 bisphenol A affects the expression of ESR1 and bisphenol A affects the expression of ESR1 mRNA CTD PMID:20170705 and PMID:26021997 Esr1 Mouse bisphenol A affects activity ISO ESR1 (Homo sapiens) 6480464 bisphenol A affects the activity of ESR1 protein CTD PMID:18635651 Esr1 Mouse bisphenol A affects binding ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A binds to ESR1 protein CTD PMID:11086226 more ... Esr1 Mouse bisphenol A affects expression ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of ESR1 more ... CTD PMID:17592034 more ... Esr1 Mouse bisphenol A affects activity EXP 6480464 bisphenol A affects the activity of ESR1 protein CTD PMID:21251949 Esr1 Mouse bisphenol A multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA more ... CTD PMID:10580743 more ... Esr1 Mouse bisphenol A increases methylation ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of ESR1 gene and bisphenol A results in increased methylation of ESR1 promoter CTD PMID:21827818 and PMID:28505145 Esr1 Mouse bisphenol A affects localization ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A affects the localization of ESR1 protein CTD PMID:19479021 Esr1 Mouse bisphenol A affects localization EXP 6480464 bisphenol A affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ESR1 more ... CTD PMID:20599497 more ... Esr1 Mouse bisphenol A multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased phosphorylation of ESR1 protein] more ... CTD PMID:10965916 more ... Esr1 Mouse bisphenol A affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 affects the susceptibility to bisphenol A more ... CTD PMID:19492024 more ... Esr1 Mouse Bisphenol A diglycidyl ether multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:32619634 Esr1 Mouse bisphenol A dimethacrylate multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:11145352 and PMID:37696476 Esr1 Mouse Bisphenol A glycidylmethacrylate increases activity ISO ESR1 (Homo sapiens) 6480464 Bisphenol A-Glycidyl Methacrylate results in increased activity of ESR1 protein CTD PMID:11145352 Esr1 Mouse Bisphenol A glycidylmethacrylate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Bisphenol A-Glycidyl Methacrylate co-treated with 2 more ... CTD PMID:11145352 and PMID:37696476 Esr1 Mouse Bisphenol B multiple interactions ISO ESR1 (Homo sapiens) 6480464 [bisphenol B co-treated with bisphenol A] results in increased expression of ESR1 protein more ... CTD PMID:21256200 more ... Esr1 Mouse Bisphenol B affects localization EXP 6480464 bisphenol B affects the localization of ESR1 protein CTD PMID:33392205 Esr1 Mouse Bisphenol B increases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol B results in increased expression of ESR1 protein CTD PMID:38133387 Esr1 Mouse Bisphenol B increases activity ISO ESR1 (Homo sapiens) 6480464 bisphenol B results in increased activity of ESR1 protein CTD PMID:30582956 more ... Esr1 Mouse Bisphenol B affects binding ISO ESR1 (Homo sapiens) 6480464 bisphenol B binds to ESR1 protein CTD PMID:30143207 Esr1 Mouse Bisphenol B decreases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol B results in decreased expression of ESR1 protein CTD PMID:24856822 Esr1 Mouse Bisphenol B increases activity ISO Esr1 (Rattus norvegicus) 6480464 bisphenol B results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse Bisphenol B affects activity EXP 6480464 bisphenol B affects the activity of ESR1 protein CTD PMID:23611293 Esr1 Mouse bisphenol F affects binding ISO Esr1 (Rattus norvegicus) 6480464 4 and 4'-bisphenol F binds to ESR1 protein CTD PMID:27420082 Esr1 Mouse bisphenol F decreases expression ISO ESR1 (Homo sapiens) 6480464 bisphenol F results in decreased expression of ESR1 protein CTD PMID:31995776 and PMID:34831106 Esr1 Mouse bisphenol F affects binding ISO ESR1 (Homo sapiens) 6480464 bisphenol F binds to ESR1 protein CTD PMID:31836225 Esr1 Mouse bisphenol F increases activity ISO ESR1 (Homo sapiens) 6480464 4 more ... CTD PMID:30582956 more ... Esr1 Mouse bisphenol F increases expression EXP 6480464 4 and 4'-bisphenol F results in increased expression of ESR1 mRNA CTD PMID:30196065 Esr1 Mouse bisphenol F multiple interactions ISO ESR1 (Homo sapiens) 6480464 4 more ... CTD PMID:15110108 more ... Esr1 Mouse bisphenol F increases expression ISO ESR1 (Homo sapiens) 6480464 4 more ... CTD PMID:18973785 and PMID:30195206 Esr1 Mouse bisphenol F diglycidyl ether multiple interactions ISO ESR1 (Homo sapiens) 6480464 bisphenol F diglycidyl ether analog inhibits the reaction [Coumestrol binds to ESR1 protein] and bisphenol F diglycidyl ether inhibits the reaction [Coumestrol binds to ESR1 protein] CTD PMID:32619634 Esr1 Mouse bortezomib multiple interactions ISO ESR1 (Homo sapiens) 6480464 Bortezomib binds to and results in decreased activity of ESR1 protein and Bortezomib inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:25752796 and PMID:30818834 Esr1 Mouse brassinolide decreases expression ISO ESR1 (Homo sapiens) 6480464 brassinolide results in decreased expression of ESR1 CTD PMID:20833159 Esr1 Mouse bromocriptine multiple interactions EXP 6480464 [Bromocriptine co-treated with Estradiol] results in increased expression of ESR1 protein CTD PMID:11786374 Esr1 Mouse bromoethane increases expression ISO ESR1 (Homo sapiens) 6480464 bromoethane results in increased expression of ESR1 mRNA and bromoethane results in increased expression of ESR1 protein CTD PMID:15922381 Esr1 Mouse bromoethane increases expression EXP 6480464 bromoethane results in increased expression of ESR1 mRNA and bromoethane results in increased expression of ESR1 protein CTD PMID:15922381 Esr1 Mouse Bromofos increases activity ISO ESR1 (Homo sapiens) 6480464 bromophos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse Bromophos-ethyl increases activity ISO ESR1 (Homo sapiens) 6480464 ethyl bromophos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse bromuconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 bromuconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse bucladesine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Bucladesine results in increased expression of ESR1 mRNA CTD PMID:21693180 Esr1 Mouse bucladesine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Quercetin co-treated with Bucladesine] results in increased expression of ESR1 mRNA and Atrazine inhibits the reaction [Bucladesine results in increased expression of ESR1 mRNA] CTD PMID:21693180 and PMID:23200735 Esr1 Mouse butylated hydroxyanisole increases activity ISO ESR1 (Homo sapiens) 6480464 Butylated Hydroxyanisole results in increased activity of ESR1 protein CTD PMID:16756374 and PMID:19063592 Esr1 Mouse butylated hydroxyanisole affects binding ISO ESR1 (Homo sapiens) 6480464 Butylated Hydroxyanisole binds to ESR1 protein CTD PMID:12822488 and PMID:14579009 Esr1 Mouse butylated hydroxyanisole multiple interactions ISO ESR1 (Homo sapiens) 6480464 Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12822488 and PMID:14579009 Esr1 Mouse butylated hydroxyanisole decreases expression ISO ESR1 (Homo sapiens) 6480464 Butylated Hydroxyanisole results in decreased expression of ESR1 mRNA CTD PMID:12822488 Esr1 Mouse Butylbenzyl phthalate decreases methylation ISO ESR1 (Homo sapiens) 6480464 butylbenzyl phthalate results in decreased methylation of ESR1 gene and butylbenzyl phthalate results in decreased methylation of ESR1 promoter CTD PMID:16326419 and PMID:22949852 Esr1 Mouse Butylbenzyl phthalate decreases expression ISO ESR1 (Homo sapiens) 6480464 butylbenzyl phthalate results in decreased expression of ESR1 mRNA and butylbenzyl phthalate results in decreased expression of ESR1 protein CTD PMID:30851587 Esr1 Mouse Butylbenzyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein more ... CTD PMID:28013214 more ... Esr1 Mouse Butylbenzyl phthalate increases activity ISO ESR1 (Homo sapiens) 6480464 butylbenzyl phthalate results in increased activity of ESR1 protein CTD PMID:28571686 Esr1 Mouse Butylbenzyl phthalate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Zeranol co-treated with butylbenzyl phthalate] affects the expression of ESR1 protein CTD PMID:35163327 Esr1 Mouse Butylbenzyl phthalate affects binding EXP 6480464 butylbenzyl phthalate binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse Butylbenzyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 butylbenzyl phthalate binds to ESR1 protein CTD PMID:19913605 more ... Esr1 Mouse Butylbenzyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 butylbenzyl phthalate binds to and results in increased activity of ESR1 protein more ... CTD PMID:15840436 more ... Esr1 Mouse Butylparaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer] more ... CTD PMID:20362049 more ... Esr1 Mouse Butylparaben decreases activity ISO ESR1 (Homo sapiens) 6480464 butylparaben results in decreased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse Butylparaben decreases methylation ISO Esr1 (Rattus norvegicus) 6480464 butylparaben results in decreased methylation of ESR1 promoter CTD PMID:26888303 Esr1 Mouse Butylparaben decreases expression ISO Esr1 (Rattus norvegicus) 6480464 butylparaben results in decreased expression of ESR1 mRNA and butylparaben results in decreased expression of ESR1 protein CTD PMID:19654335 and PMID:27444704 Esr1 Mouse Butylparaben increases expression ISO Esr1 (Rattus norvegicus) 6480464 butylparaben results in increased expression of ESR1 mRNA and butylparaben results in increased expression of ESR1 protein CTD PMID:26888303 Esr1 Mouse Butylparaben increases activity ISO ESR1 (Homo sapiens) 6480464 butylparaben results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse Butylparaben increases expression ISO ESR1 (Homo sapiens) 6480464 butylparaben results in increased expression of ESR1 mRNA and butylparaben results in increased expression of ESR1 protein CTD PMID:25128701 Esr1 Mouse Butylparaben multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides more ... CTD PMID:15204698 more ... Esr1 Mouse Butylparaben decreases expression ISO ESR1 (Homo sapiens) 6480464 butylparaben results in decreased expression of ESR1 mRNA CTD PMID:23524099 Esr1 Mouse Butylparaben affects binding ISO ESR1 (Homo sapiens) 6480464 butylparaben binds to ESR1 protein and butylparaben metabolite binds to ESR1 protein CTD PMID:11193391 more ... Esr1 Mouse Butylparaben affects binding ISO Esr1 (Rattus norvegicus) 6480464 butylparaben binds to ESR1 protein CTD PMID:15204698 and PMID:20132880 Esr1 Mouse cadmium atom decreases expression ISO ESR1 (Homo sapiens) 6480464 Cadmium results in decreased expression of ESR1 mRNA and Cadmium results in decreased expression of ESR1 protein CTD PMID:17125913 and PMID:31646340 Esr1 Mouse cadmium atom increases splicing ISO Esr1 (Rattus norvegicus) 6480464 Cadmium results in increased splicing of ESR1 mRNA CTD PMID:24236210 Esr1 Mouse cadmium atom increases expression ISO Esr1 (Rattus norvegicus) 6480464 Cadmium results in increased expression of ESR1 mRNA more ... CTD PMID:24236210 Esr1 Mouse cadmium atom multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Cadmium promotes the reaction [Estradiol results in increased expression of ESR1 mRNA] and Estradiol promotes the reaction [Cadmium results in increased expression of ESR1 mRNA] CTD PMID:24236210 Esr1 Mouse cadmium atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased ubiquitination of ESR1 protein more ... CTD PMID:10770491 more ... Esr1 Mouse cadmium atom increases activity ISO ESR1 (Homo sapiens) 6480464 Cadmium results in increased activity of ESR1 protein and Cadmium results in increased activity of ESR1 protein mutant form CTD PMID:16635015 Esr1 Mouse cadmium dichloride decreases expression ISO ESR1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of ESR1 protein CTD PMID:17125913 Esr1 Mouse cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of ESR1 protein CTD PMID:37482142 Esr1 Mouse cadmium dichloride increases expression ISO ESR1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ESR1 protein CTD PMID:30682495 Esr1 Mouse cadmium dichloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased ubiquitination of ESR1 protein more ... CTD PMID:20219890 more ... Esr1 Mouse cadmium dichloride increases activity ISO ESR1 (Homo sapiens) 6480464 Cadmium Chloride results in increased activity of ESR1 protein CTD PMID:17716812 Esr1 Mouse cadmium dichloride affects localization ISO ESR1 (Homo sapiens) 6480464 Cadmium Chloride affects the localization of ESR1 protein CTD PMID:20219890 Esr1 Mouse cadmium dichloride increases splicing ISO Esr1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased splicing of ESR1 mRNA CTD PMID:24236210 Esr1 Mouse cadmium dichloride multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Cadmium Chloride promotes the reaction [Estradiol results in increased expression of ESR1 mRNA] and Estradiol promotes the reaction [Cadmium Chloride results in increased expression of ESR1 mRNA] CTD PMID:24236210 Esr1 Mouse cadmium dichloride increases expression ISO Esr1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of ESR1 mRNA more ... CTD PMID:24236210 and PMID:33453195 Esr1 Mouse cadmium dichloride decreases methylation ISO Esr1 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased methylation of ESR1 promoter CTD PMID:22457795 Esr1 Mouse calcitriol increases expression ISO ESR1 (Homo sapiens) 6480464 Calcitriol results in increased expression of ESR1 mRNA CTD PMID:16002434 and PMID:26485663 Esr1 Mouse calcium dihydroxide increases expression ISO ESR1 (Homo sapiens) 6480464 Calcium Hydroxide results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse camphor multiple interactions ISO ESR1 (Homo sapiens) 6480464 Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse camptothecin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Camptothecin binds to and results in decreased activity of ESR1 protein more ... CTD PMID:25752796 and PMID:30720231 Esr1 Mouse captan affects binding ISO ESR1 (Homo sapiens) 6480464 Captan binds to ESR1 protein CTD PMID:15253041 Esr1 Mouse carbamazepine multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 mRNA] and benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 protein] CTD PMID:16965676 Esr1 Mouse carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of ESR1 mRNA CTD PMID:19490052 Esr1 Mouse carbamazepine decreases expression ISO ESR1 (Homo sapiens) 6480464 Carbamazepine results in decreased expression of ESR1 mRNA and Carbamazepine results in decreased expression of ESR1 protein CTD PMID:16965676 Esr1 Mouse carbaryl multiple interactions ISO ESR1 (Homo sapiens) 6480464 Carbaryl binds to and results in decreased activity of ESR1 protein and Carbaryl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:16626760 and PMID:9126867 Esr1 Mouse carbendazim decreases expression ISO Esr1 (Rattus norvegicus) 6480464 carbendazim results in decreased expression of ESR1 mRNA CTD PMID:28576679 Esr1 Mouse carbendazim affects localization EXP 6480464 carbendazim affects the localization of ESR1 protein CTD PMID:37506866 Esr1 Mouse carbon nanotube decreases expression EXP 6480464 Nanotubes and Carbon results in decreased expression of ESR1 mRNA CTD PMID:25620056 Esr1 Mouse carfilzomib multiple interactions ISO ESR1 (Homo sapiens) 6480464 carfilzomib inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse cedrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 cedrol binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse chloramphenicol increases expression ISO ESR1 (Homo sapiens) 6480464 Chloramphenicol results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse chlordecone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Chlordecone binds to and results in increased activity of ESR1 protein more ... CTD PMID:10774817 more ... Esr1 Mouse chlordecone increases expression ISO ESR1 (Homo sapiens) 6480464 Chlordecone results in increased expression of ESR1 protein CTD PMID:33837044 Esr1 Mouse chlordecone increases expression EXP 6480464 Chlordecone results in increased expression of ESR1 protein CTD PMID:17640991 and PMID:29980752 Esr1 Mouse chlordecone multiple interactions EXP 6480464 Chlordecone promotes the reaction [ESR1 protein binds to HSPA5 protein] more ... CTD PMID:17640991 and PMID:29980752 Esr1 Mouse chlordecone affects binding EXP 6480464 Chlordecone binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse chlordecone affects binding ISO ESR1 (Homo sapiens) 6480464 Chlordecone binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse chlordecone increases activity ISO ESR1 (Homo sapiens) 6480464 Chlordecone results in increased activity of ESR1 protein mutant form CTD PMID:17141713 Esr1 Mouse chlormidazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 chlormidazole inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse chlornitrofen multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:12676605 Esr1 Mouse chlornitrofen increases activity ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:15064155 Esr1 Mouse chlornitrofen affects binding ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:12676605 Esr1 Mouse chlorobenzenes multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse Chlorobenzilate increases activity ISO ESR1 (Homo sapiens) 6480464 chlorobenzilate results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse Chlorobenzilate multiple interactions ISO ESR1 (Homo sapiens) 6480464 chlorobenzilate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse chlorogenic acid decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Chlorogenic Acid results in decreased expression of ESR1 protein CTD PMID:29899696 Esr1 Mouse chlorohydrocarbon multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [[Hydrocarbons more ... CTD PMID:31923581 Esr1 Mouse chloropropylate increases activity ISO ESR1 (Homo sapiens) 6480464 chloropropylate results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse chlorpyrifos decreases activity ISO ESR1 (Homo sapiens) 6480464 Chlorpyrifos results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse chlorpyrifos increases expression ISO ESR1 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of ESR1 mRNA CTD PMID:35457321 Esr1 Mouse chlorpyrifos multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Triiodothyronine] results in increased expression of ESR1 mRNA CTD PMID:34571837 Esr1 Mouse chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of ESR1 mRNA CTD PMID:34571837 Esr1 Mouse chlorpyrifos affects expression ISO Esr1 (Rattus norvegicus) 6480464 Chlorpyrifos affects the expression of ESR1 mRNA CTD PMID:34858468 Esr1 Mouse chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of ESR1 protein CTD PMID:34571837 and PMID:36769379 Esr1 Mouse chlorpyrifos decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of ESR1 protein modified form CTD PMID:26518068 Esr1 Mouse chlorpyrifos decreases expression ISO ESR1 (Homo sapiens) 6480464 Chlorpyrifos results in decreased expression of ESR1 mRNA CTD PMID:32171938 Esr1 Mouse chlorpyrifos increases activity ISO ESR1 (Homo sapiens) 6480464 Chlorpyrifos results in increased activity of ESR1 protein CTD PMID:15064155 more ... Esr1 Mouse chlorpyrifos multiple interactions ISO ESR1 (Homo sapiens) 6480464 [APOE gene polymorphism affects the susceptibility to Chlorpyrifos] which affects the expression of ESR1 mRNA more ... CTD PMID:26812056 more ... Esr1 Mouse chlorpyrifos-methyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 chlorpyrifos-methyl binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse chromium(6+) decreases expression ISO Esr1 (Rattus norvegicus) 6480464 chromium hexavalent ion results in decreased expression of ESR1 mRNA CTD PMID:18602937 Esr1 Mouse chromium(6+) multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of ESR1 protein and Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA] CTD PMID:18602937 and PMID:33675932 Esr1 Mouse chrysene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with chrysene] results in increased expression of ESR1 mRNA CTD PMID:11922773 Esr1 Mouse chrysene increases expression ISO ESR1 (Homo sapiens) 6480464 chrysene results in increased expression of ESR1 mRNA CTD PMID:11922773 Esr1 Mouse chrysin multiple interactions ISO ESR1 (Homo sapiens) 6480464 chrysin binds to and results in increased activity of ESR1 protein more ... CTD PMID:16972788 more ... Esr1 Mouse Ciclesonide multiple interactions ISO ESR1 (Homo sapiens) 6480464 ciclesonide binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse ciclopirox multiple interactions ISO ESR1 (Homo sapiens) 6480464 ciclopirox binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of ESR1 mRNA CTD PMID:18353800 Esr1 Mouse cilnidipine decreases activity ISO ESR1 (Homo sapiens) 6480464 cilnidipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse cisplatin increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 results in increased susceptibility to Cisplatin CTD PMID:21767602 Esr1 Mouse cisplatin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estrone inhibits the reaction [ESR1 results in increased susceptibility to Cisplatin] CTD PMID:21767602 Esr1 Mouse citral affects binding ISO ESR1 (Homo sapiens) 6480464 citral binds to ESR1 protein CTD PMID:12495555 Esr1 Mouse citral multiple interactions ISO ESR1 (Homo sapiens) 6480464 citral inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12495555 Esr1 Mouse clofibrate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 [Clofibrate results in decreased expression of ESR1 mRNA] which results in decreased expression of LIFR mRNA and Clofibrate results in decreased expression of ESR1 mRNA CTD PMID:22467018 Esr1 Mouse clomiphene multiple interactions ISO ESR1 (Homo sapiens) 6480464 Clomiphene binds to and results in decreased activity of ESR1 protein more ... CTD PMID:19233257 more ... Esr1 Mouse clomiphene affects binding ISO ESR1 (Homo sapiens) 6480464 Clomiphene binds to ESR1 protein CTD PMID:15521089 and PMID:19233257 Esr1 Mouse cobalt atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 Zinc inhibits the reaction [Cobalt binds to ESR1 protein] CTD PMID:14640689 Esr1 Mouse cobalt atom affects binding ISO ESR1 (Homo sapiens) 6480464 Cobalt binds to ESR1 protein CTD PMID:14640689 Esr1 Mouse cobalt dichloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 cobaltous chloride binds to and results in increased activity of ESR1 protein more ... CTD PMID:12746304 Esr1 Mouse cobalt dichloride affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to cobaltous chloride CTD PMID:12746304 Esr1 Mouse cobalt dichloride decreases expression ISO ESR1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ESR1 mRNA and cobaltous chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse colforsin daropate hydrochloride decreases expression ISO ESR1 (Homo sapiens) 6480464 Colforsin results in decreased expression of ESR1 mRNA CTD PMID:31278978 Esr1 Mouse conjugated linoleic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 Linoleic Acids more ... CTD PMID:19800873 Esr1 Mouse copper(II) chloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein] more ... CTD PMID:12746304 Esr1 Mouse copper(II) chloride increases activity ISO ESR1 (Homo sapiens) 6480464 cupric chloride results in increased activity of ESR1 protein CTD PMID:12746304 and PMID:17716812 Esr1 Mouse copper(II) chloride affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to cupric chloride CTD PMID:12746304 Esr1 Mouse copper(II) chloride decreases expression ISO ESR1 (Homo sapiens) 6480464 cupric chloride results in decreased expression of ESR1 mRNA and cupric chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse corticosterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [ESR1 protein binds to TRAF6 protein] CTD PMID:29625166 Esr1 Mouse cortisol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Hydrocortisone binds to and results in increased activity of ESR1 protein CTD PMID:12676605 Esr1 Mouse coumaphos multiple interactions ISO ESR1 (Homo sapiens) 6480464 Coumaphos binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse coumarins decreases expression ISO ESR1 (Homo sapiens) 6480464 Coumarins analog results in decreased expression of ESR1 protein CTD PMID:17275315 Esr1 Mouse coumestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:10397250 more ... Esr1 Mouse coumestrol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Coumestrol results in decreased expression of ESR1 protein CTD PMID:34848279 Esr1 Mouse coumestrol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Fulvestrant co-treated with Coumestrol] results in increased expression of ESR1 mRNA and Fulvestrant inhibits the reaction [Coumestrol results in decreased expression of ESR1 protein] CTD PMID:34848279 Esr1 Mouse coumestrol affects response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein affects the susceptibility to Coumestrol CTD PMID:19400946 Esr1 Mouse coumestrol increases activity ISO Esr1 (Rattus norvegicus) 6480464 Coumestrol results in increased activity of ESR1 protein CTD PMID:17174995 Esr1 Mouse coumestrol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Coumestrol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse coumestrol affects binding EXP 6480464 Coumestrol binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse coumestrol affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to Coumestrol CTD PMID:17275032 Esr1 Mouse coumestrol increases activity ISO ESR1 (Homo sapiens) 6480464 Coumestrol results in increased activity of ESR1 protein CTD PMID:16118406 more ... Esr1 Mouse coumestrol decreases expression ISO ESR1 (Homo sapiens) 6480464 Coumestrol results in decreased expression of ESR1 protein CTD PMID:11867264 Esr1 Mouse coumestrol affects binding ISO ESR1 (Homo sapiens) 6480464 Coumestrol binds to ESR1 protein and Coumestrol binds to ESR1 protein modified form CTD PMID:11162928 more ... Esr1 Mouse curcumin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of ESR1 protein] more ... CTD PMID:15899841 more ... Esr1 Mouse curcumin decreases expression ISO ESR1 (Homo sapiens) 6480464 Curcumin results in decreased expression of ESR1 protein CTD PMID:18347134 more ... Esr1 Mouse cyanazine affects binding ISO ESR1 (Homo sapiens) 6480464 cyanazine binds to ESR1 protein CTD PMID:8858116 Esr1 Mouse cyanazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 cyanazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein] CTD PMID:8858116 Esr1 Mouse Cyanofenphos increases activity ISO ESR1 (Homo sapiens) 6480464 cyanophenphos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse cycloheximide decreases expression ISO ESR1 (Homo sapiens) 6480464 Cycloheximide results in decreased expression of ESR1 protein CTD PMID:24586459 Esr1 Mouse cycloheximide multiple interactions ISO ESR1 (Homo sapiens) 6480464 bisphenol A promotes the reaction [Cycloheximide results in decreased expression of ESR1 protein] more ... CTD PMID:24586459 Esr1 Mouse cyclophosphamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA CTD PMID:16322899 Esr1 Mouse cycloprothrin decreases activity ISO Esr1 (Rattus norvegicus) 6480464 cycloprothrin results in decreased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse cyclosporin A increases methylation ISO ESR1 (Homo sapiens) 6480464 Cyclosporine results in increased methylation of ESR1 promoter CTD PMID:27989131 Esr1 Mouse cyfluthrin increases activity ISO ESR1 (Homo sapiens) 6480464 cyfluthrin results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse cyfluthrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 cyfluthrin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse cyfluthrin decreases activity ISO Esr1 (Rattus norvegicus) 6480464 cyfluthrin results in decreased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse cyhalothrin increases activity ISO Esr1 (Rattus norvegicus) 6480464 cyhalothrin results in increased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of ESR1 CTD PMID:26969072 Esr1 Mouse cyhalothrin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of ESR1] and fulvestrant inhibits the reaction [cyhalothrin results in increased expression of ESR1] CTD PMID:26969072 Esr1 Mouse cyhalothrin decreases expression ISO ESR1 (Homo sapiens) 6480464 cyhalothrin results in decreased expression of ESR1 mRNA and cyhalothrin results in decreased expression of ESR1 protein CTD PMID:18419197 and PMID:20097460 Esr1 Mouse cypermethrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 cypermethrin binds to and results in increased activity of ESR1 protein and cypermethrin metabolite binds to and results in increased activity of ESR1 protein CTD PMID:16395479 and PMID:33049310 Esr1 Mouse cypermethrin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [cypermethrin co-treated with emamectin benzoate] results in decreased expression of ESR1 mRNA more ... CTD PMID:28531659 and PMID:37984602 Esr1 Mouse cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of ESR1 mRNA and cypermethrin results in increased expression of ESR1 protein CTD PMID:20574910 more ... Esr1 Mouse cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of ESR1 mRNA and cypermethrin results in decreased expression of ESR1 protein CTD PMID:24810582 and PMID:36116546 Esr1 Mouse cypermethrin increases expression ISO Esr1 (Rattus norvegicus) 6480464 cypermethrin results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse cypermethrin increases expression ISO ESR1 (Homo sapiens) 6480464 cypermethrin results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse cypermethrin affects binding ISO ESR1 (Homo sapiens) 6480464 cypermethrin binds to ESR1 protein CTD PMID:20574910 Esr1 Mouse cypermethrin decreases expression ISO ESR1 (Homo sapiens) 6480464 cypermethrin results in decreased expression of ESR1 mRNA CTD PMID:20397420 and PMID:33677314 Esr1 Mouse cypermethrin affects binding ISO Esr1 (Rattus norvegicus) 6480464 cypermethrin binds to ESR1 protein CTD PMID:12396874 Esr1 Mouse cypermethrin increases activity ISO ESR1 (Homo sapiens) 6480464 cypermethrin results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse cyprodinil affects binding ISO ESR1 (Homo sapiens) 6480464 cyprodinil binds to ESR1 protein CTD PMID:27999363 Esr1 Mouse cyprodinil increases activity ISO Esr1 (Rattus norvegicus) 6480464 cyprodinil results in increased activity of ESR1 protein CTD PMID:33352482 Esr1 Mouse cyproterone acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Cyproterone Acetate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse D-aspartic acid increases expression ISO Esr1 (Rattus norvegicus) 6480464 D-Aspartic Acid results in increased expression of ESR1 mRNA CTD PMID:26044185 Esr1 Mouse D-aspartic acid decreases expression ISO Esr1 (Rattus norvegicus) 6480464 D-Aspartic Acid results in decreased expression of ESR1 protein CTD PMID:24439162 Esr1 Mouse D-glucose decreases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in decreased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse D-glucose increases abundance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased abundance of Glucose CTD PMID:31520823 Esr1 Mouse D-glucose multiple interactions ISO ESR1 (Homo sapiens) 6480464 Endosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose] CTD PMID:31520823 Esr1 Mouse D-glucose increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of ESR1 protein CTD PMID:23690508 Esr1 Mouse D-glucose multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA more ... CTD PMID:18426865 and PMID:37606869 Esr1 Mouse D-glucose increases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse daidzein affects response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein affects the susceptibility to daidzein CTD PMID:19400946 Esr1 Mouse daidzein increases activity ISO ESR1 (Homo sapiens) 6480464 daidzein results in increased activity of ESR1 protein CTD PMID:16118406 more ... Esr1 Mouse daidzein affects binding ISO ESR1 (Homo sapiens) 6480464 daidzein binds to ESR1 protein CTD PMID:12598185 more ... Esr1 Mouse daidzein affects binding EXP 6480464 daidzein binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse daidzein affects binding ISO Esr1 (Rattus norvegicus) 6480464 daidzein binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse daidzein increases expression ISO ESR1 (Homo sapiens) 6480464 daidzein results in increased expression of ESR1 mRNA and daidzein results in increased expression of ESR1 protein CTD PMID:27576059 Esr1 Mouse daidzein increases activity EXP 6480464 daidzein results in increased activity of ESR1 protein CTD PMID:19495926 Esr1 Mouse daidzein decreases expression ISO ESR1 (Homo sapiens) 6480464 daidzein results in decreased expression of ESR1 mRNA and daidzein results in decreased expression of ESR1 protein CTD PMID:16033089 Esr1 Mouse daidzein multiple interactions ISO ESR1 (Homo sapiens) 6480464 [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein more ... CTD PMID:12650720 more ... Esr1 Mouse danazol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Danazol binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse daunorubicin decreases activity ISO ESR1 (Homo sapiens) 6480464 Daunorubicin results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse daunorubicin increases activity ISO ESR1 (Homo sapiens) 6480464 Daunorubicin results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse DDD increases activity ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyldichloroethane analog results in increased activity of ESR1 protein and Dichlorodiphenyldichloroethane results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26022396 Esr1 Mouse DDD multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyldichloroethane binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse DDD increases expression ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyldichloroethane results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse DDE increases activity ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene analog results in increased activity of ESR1 protein and Dichlorodiphenyl Dichloroethylene results in increased activity of ESR1 protein CTD PMID:15064155 more ... Esr1 Mouse DDE multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [o more ... CTD PMID:34383603 and PMID:9860891 Esr1 Mouse DDE increases activity ISO Esr1 (Rattus norvegicus) 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of ESR1 protein CTD PMID:17174995 and PMID:9860891 Esr1 Mouse DDE increases expression ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse DDE multiple interactions EXP 6480464 [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of ESR1 mRNA CTD PMID:16758953 Esr1 Mouse DDE decreases expression ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of ESR1 mRNA CTD PMID:20206645 Esr1 Mouse DDE affects binding ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene binds to ESR1 protein and Dichlorodiphenyl Dichloroethylene metabolite binds to ESR1 protein CTD PMID:10492897 more ... Esr1 Mouse DDE multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene binds to and results in increased activity of ESR1 protein more ... CTD PMID:14579009 more ... Esr1 Mouse DDT increases expression ISO ESR1 (Homo sapiens) 6480464 DDT results in increased expression of ESR1 mRNA CTD PMID:21295777 and PMID:25014179 Esr1 Mouse DDT increases expression ISO Esr1 (Rattus norvegicus) 6480464 DDT results in increased expression of ESR1 mRNA CTD PMID:29477483 Esr1 Mouse DDT decreases expression EXP 6480464 DDT results in decreased expression of ESR1 protein CTD PMID:28263910 Esr1 Mouse DDT increases methylation EXP 6480464 DDT results in increased methylation of ESR1 gene CTD PMID:28263910 Esr1 Mouse DDT decreases expression ISO ESR1 (Homo sapiens) 6480464 DDT results in decreased expression of ESR1 mRNA CTD PMID:33728745 Esr1 Mouse DDT increases activity ISO ESR1 (Homo sapiens) 6480464 DDT results in increased activity of ESR1 protein CTD PMID:11485867 more ... Esr1 Mouse DDT multiple interactions EXP 6480464 DDT promotes the reaction [ESR1 protein binds to CCND1 promoter] and DDT promotes the reaction [ESR1 protein binds to CDKN1A promoter] CTD PMID:23684557 Esr1 Mouse DDT multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [o and p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR1 protein CTD PMID:9860891 Esr1 Mouse DDT increases activity ISO Esr1 (Rattus norvegicus) 6480464 DDT results in increased activity of ESR1 protein CTD PMID:9860891 Esr1 Mouse DDT affects binding EXP 6480464 DDT binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse DDT affects binding ISO ESR1 (Homo sapiens) 6480464 DDT binds to ESR1 protein CTD PMID:12676605 and PMID:19913605 Esr1 Mouse DDT increases expression EXP 6480464 DDT results in increased expression of ESR1 mRNA and DDT results in increased expression of ESR1 protein CTD PMID:15541753 and PMID:28263910 Esr1 Mouse DDT multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA more ... CTD PMID:12676605 more ... Esr1 Mouse dehydroepiandrosterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dehydroepiandrosterone binds to and results in increased activity of ESR1 protein more ... CTD PMID:15994348 more ... Esr1 Mouse dehydroepiandrosterone increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Dehydroepiandrosterone results in increased phosphorylation of ESR1 protein CTD PMID:25969534 Esr1 Mouse dehydroepiandrosterone increases expression ISO ESR1 (Homo sapiens) 6480464 Dehydroepiandrosterone results in increased expression of ESR1 mRNA alternative form and Dehydroepiandrosterone results in increased expression of ESR1 protein alternative form CTD PMID:25969534 Esr1 Mouse dehydroepiandrosterone affects binding ISO ESR1 (Homo sapiens) 6480464 Dehydroepiandrosterone binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse dehydroepiandrosterone affects binding EXP 6480464 Dehydroepiandrosterone binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse deisopropylatrazine affects binding ISO ESR1 (Homo sapiens) 6480464 6-deisopropylatrazine binds to ESR1 protein CTD PMID:8858116 Esr1 Mouse deisopropylatrazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 6-deisopropylatrazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein] CTD PMID:8858116 Esr1 Mouse delta-hexachlorocyclohexane increases activity ISO ESR1 (Homo sapiens) 6480464 delta-hexachlorocyclohexane results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26022396 Esr1 Mouse delta-tocopherol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA] and [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 Esr1 Mouse Deoxymiroestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 deoxymiroestrol binds to and results in increased activity of ESR1 protein CTD PMID:15876408 Esr1 Mouse deoxynivalenol increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 deoxynivalenol results in increased phosphorylation of ESR1 protein CTD PMID:35588983 Esr1 Mouse deoxynivalenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA] and ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA] CTD PMID:35588983 Esr1 Mouse dexamethasone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Estradiol co-treated with Dexamethasone] results in decreased expression of ESR1 mRNA more ... CTD PMID:23183181 and PMID:25136773 Esr1 Mouse dexamethasone multiple interactions EXP 6480464 [[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR1 protein and [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ESR1 mRNA CTD PMID:26944108 and PMID:28849599 Esr1 Mouse dexamethasone decreases expression ISO ESR1 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of ESR1 mRNA CTD PMID:16691199 and PMID:19022236 Esr1 Mouse dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ESR1 mRNA CTD PMID:29950665 Esr1 Mouse dextran sulfate decreases expression EXP 6480464 Dextran Sulfate results in decreased expression of ESR1 mRNA CTD PMID:30270565 Esr1 Mouse Di-n-hexyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 di-n-hexyl phthalate analog binds to ESR1 protein CTD PMID:15464722 Esr1 Mouse Di-n-hexyl phthalate increases expression ISO Esr1 (Rattus norvegicus) 6480464 di-n-hexyl phthalate results in increased expression of ESR1 mRNA CTD PMID:22112501 Esr1 Mouse Di-n-hexyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 di-n-hexyl phthalate binds to and results in increased activity of ESR1 protein more ... CTD PMID:15840436 and PMID:28571686 Esr1 Mouse Di-n-octyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 di-n-octyl phthalate analog binds to ESR1 protein CTD PMID:15464722 Esr1 Mouse Di-n-octyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR1 protein CTD PMID:35739755 and PMID:37364641 Esr1 Mouse Di-n-octyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28571686 Esr1 Mouse Diallyl sulfide multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein alternative form promotes the reaction [allyl sulfide inhibits the reaction [Estradiol results in decreased cleavage of CASP3 protein]] more ... CTD PMID:34724321 Esr1 Mouse Diallyl sulfide decreases expression ISO ESR1 (Homo sapiens) 6480464 allyl sulfide results in decreased expression of ESR1 protein alternative form CTD PMID:34724321 Esr1 Mouse diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of ESR1 protein CTD PMID:34050381 Esr1 Mouse diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased methylation of ESR1 gene more ... CTD PMID:23159075 Esr1 Mouse diarsenic trioxide increases expression ISO ESR1 (Homo sapiens) 6480464 [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA more ... CTD PMID:20458559 more ... Esr1 Mouse diarsenic trioxide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Arsenic Trioxide results in decreased methylation of ESR1 promoter] which results in increased expression of ESR1 mRNA more ... CTD PMID:15283693 more ... Esr1 Mouse diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ESR1 mRNA and Arsenic Trioxide results in increased expression of ESR1 protein CTD PMID:15073043 and PMID:23159075 Esr1 Mouse diarsenic trioxide decreases methylation ISO ESR1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased methylation of ESR1 gene and Arsenic Trioxide results in decreased methylation of ESR1 promoter CTD PMID:21687957 and PMID:23159075 Esr1 Mouse diarsenic trioxide decreases methylation EXP 6480464 Arsenic Trioxide results in decreased methylation of ESR1 promoter CTD PMID:15073043 Esr1 Mouse diarsenic trioxide decreases expression ISO ESR1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of ESR1 mRNA and Arsenic Trioxide results in decreased expression of ESR1 protein CTD PMID:12014631 more ... Esr1 Mouse diarylheptanoid increases expression ISO ESR1 (Homo sapiens) 6480464 Diarylheptanoids results in increased expression of ESR1 mRNA CTD PMID:23552522 Esr1 Mouse diarylheptanoid increases activity EXP 6480464 Diarylheptanoids results in increased activity of ESR1 protein CTD PMID:19654927 Esr1 Mouse diarylheptanoid increases activity ISO ESR1 (Homo sapiens) 6480464 Diarylheptanoids results in increased activity of ESR1 protein CTD PMID:19654927 Esr1 Mouse diarylheptanoid multiple interactions EXP 6480464 Diarylheptanoids binds to and affects the transport of ESR1 protein more ... CTD PMID:23552522 Esr1 Mouse diarylheptanoid multiple interactions ISO ESR1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Diarylheptanoids results in increased activity of ESR1 protein] and fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of ESR1 mRNA] CTD PMID:19654927 and PMID:23552522 Esr1 Mouse diazinon decreases activity ISO ESR1 (Homo sapiens) 6480464 Diazinon results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse diazinon affects binding ISO ESR1 (Homo sapiens) 6480464 Diazinon binds to ESR1 protein CTD PMID:33872936 Esr1 Mouse diazinon increases activity ISO ESR1 (Homo sapiens) 6480464 Diazinon results in increased activity of ESR1 protein CTD PMID:28728110 Esr1 Mouse Dibenzo[a,h]pyrene increases activity ISO ESR1 (Homo sapiens) 6480464 dibenzo(a and h)pyrene results in increased activity of ESR1 protein CTD PMID:26022396 Esr1 Mouse dibenzothiophene increases expression ISO ESR1 (Homo sapiens) 6480464 dibenzothiophene results in increased expression of ESR1 mRNA CTD PMID:33314207 Esr1 Mouse dibenzoylmethane multiple interactions ISO ESR1 (Homo sapiens) 6480464 dibenzoylmethane inhibits the reaction [ESR1 protein binds to BCL2 enhancer] more ... CTD PMID:16051634 Esr1 Mouse dibromoacetic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 Esr1 Mouse Dibutyl phosphate affects expression ISO ESR1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ESR1 mRNA CTD PMID:37042841 Esr1 Mouse dibutyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Dibutyl Phthalate co-treated with Fulvestrant] results in decreased expression of ESR1 mRNA more ... CTD PMID:15840436 more ... Esr1 Mouse dibutyl phthalate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of and affects the localization of ESR1 protein CTD PMID:36308879 Esr1 Mouse dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein more ... CTD PMID:28013214 more ... Esr1 Mouse dibutyl phthalate decreases expression ISO ESR1 (Homo sapiens) 6480464 Dibutyl Phthalate results in decreased expression of ESR1 mRNA CTD PMID:35028925 Esr1 Mouse dibutyl phthalate increases activity ISO ESR1 (Homo sapiens) 6480464 Dibutyl Phthalate results in increased activity of ESR1 protein CTD PMID:28571686 Esr1 Mouse dibutyl phthalate increases activity ISO Esr1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased activity of ESR1 protein CTD PMID:19643168 Esr1 Mouse dibutyl phthalate affects binding EXP 6480464 Dibutyl Phthalate binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse dibutyl phthalate increases expression ISO Esr1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of ESR1 mRNA and Dibutyl Phthalate results in increased expression of ESR1 protein CTD PMID:24067674 Esr1 Mouse dibutyl phthalate decreases methylation ISO ESR1 (Homo sapiens) 6480464 Dibutyl Phthalate results in decreased methylation of ESR1 promoter CTD PMID:16326419 Esr1 Mouse dibutyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 Dibutyl Phthalate analog binds to ESR1 protein and Dibutyl Phthalate binds to ESR1 protein CTD PMID:15464722 more ... Esr1 Mouse Dichlofenthion increases activity ISO ESR1 (Homo sapiens) 6480464 dichlofenthion results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse dichloromethane decreases expression EXP 6480464 Methylene Chloride results in decreased expression of ESR1 mRNA CTD PMID:28392392 Esr1 Mouse dichlorvos decreases activity ISO ESR1 (Homo sapiens) 6480464 Dichlorvos results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse diclofenac affects activity ISO ESR1 (Homo sapiens) 6480464 Diclofenac affects the activity of ESR1 protein CTD PMID:29777833 Esr1 Mouse dicofol affects binding ISO ESR1 (Homo sapiens) 6480464 Dicofol binds to ESR1 protein CTD PMID:15253041 Esr1 Mouse dicofol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dicofol binds to and results in increased activity of ESR1 protein CTD PMID:10789375 more ... Esr1 Mouse dicofol increases activity ISO ESR1 (Homo sapiens) 6480464 Dicofol results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse Dicyclohexyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 dicyclohexyl phthalate binds to and results in increased activity of ESR1 protein more ... CTD PMID:15840436 more ... Esr1 Mouse dieldrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA more ... CTD PMID:10774817 more ... Esr1 Mouse dieldrin increases expression ISO ESR1 (Homo sapiens) 6480464 Dieldrin results in increased expression of ESR1 mRNA CTD PMID:11922773 and PMID:21295777 Esr1 Mouse dieldrin increases activity ISO Esr1 (Rattus norvegicus) 6480464 Dieldrin results in increased activity of ESR1 protein CTD PMID:17174995 Esr1 Mouse dieldrin decreases expression EXP 6480464 Dieldrin results in decreased expression of ESR1 protein CTD PMID:21278053 Esr1 Mouse dieldrin multiple interactions EXP 6480464 Dieldrin inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:21278053 Esr1 Mouse dieldrin increases activity ISO ESR1 (Homo sapiens) 6480464 Dieldrin results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26022396 Esr1 Mouse dieldrin affects binding ISO ESR1 (Homo sapiens) 6480464 Dieldrin binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse dienestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dienestrol binds to and results in increased activity of ESR1 protein more ... CTD PMID:15026083 more ... Esr1 Mouse dienestrol affects binding ISO ESR1 (Homo sapiens) 6480464 Dienestrol binds to ESR1 protein CTD PMID:19233257 Esr1 Mouse dienestrol decreases activity ISO ESR1 (Homo sapiens) 6480464 Dienestrol results in decreased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse diethyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 diethyl phthalate analog binds to ESR1 protein CTD PMID:15464722 Esr1 Mouse diethyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein more ... CTD PMID:28013214 more ... Esr1 Mouse diethyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 diethyl phthalate promotes the reaction [ESR1 protein binds to CYP19A1 promoter] and Tamoxifen inhibits the reaction [diethyl phthalate promotes the reaction [ESR1 protein binds to CYP19A1 promoter]] CTD PMID:24994688 Esr1 Mouse diethylstilbestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Diethylstilbestrol co-treated with ESR1 protein] results in increased expression of LTF mRNA more ... CTD PMID:10397250 more ... Esr1 Mouse diethylstilbestrol increases expression ISO ESR1 (Homo sapiens) 6480464 Diethylstilbestrol results in increased expression of ESR1 mRNA CTD PMID:29883470 and PMID:32088792 Esr1 Mouse diethylstilbestrol increases activity EXP 6480464 Diethylstilbestrol results in increased activity of ESR1 protein CTD PMID:26944108 Esr1 Mouse diethylstilbestrol affects response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein affects the susceptibility to Diethylstilbestrol CTD PMID:23620786 Esr1 Mouse diethylstilbestrol affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to Diethylstilbestrol CTD PMID:15458790 more ... Esr1 Mouse diethylstilbestrol affects activity EXP 6480464 Diethylstilbestrol affects the activity of ESR1 protein CTD PMID:16468032 and PMID:23611293 Esr1 Mouse diethylstilbestrol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in decreased expression of ESR1 mRNA and Diethylstilbestrol results in decreased expression of ESR1 protein CTD PMID:11108262 and PMID:21285323 Esr1 Mouse diethylstilbestrol affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 mRNA affects the susceptibility to Diethylstilbestrol CTD PMID:19492024 Esr1 Mouse diethylstilbestrol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of ESR1 mRNA and Diethylstilbestrol results in increased expression of ESR1 protein CTD PMID:11108262 more ... Esr1 Mouse diethylstilbestrol affects binding EXP 6480464 Diethylstilbestrol binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse diethylstilbestrol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol binds to ESR1 protein CTD PMID:15204698 and PMID:19913605 Esr1 Mouse diethylstilbestrol increases activity ISO ESR1 (Homo sapiens) 6480464 Diethylstilbestrol results in increased activity of ESR1 protein CTD PMID:11331656 more ... Esr1 Mouse diethylstilbestrol increases activity ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased activity of ESR1 protein CTD PMID:17174995 Esr1 Mouse diethylstilbestrol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of ESR1 protein] and Diethylstilbestrol inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:15204698 and PMID:18653720 Esr1 Mouse diethylstilbestrol affects expression ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol affects the expression of ESR1 mRNA more ... CTD PMID:17592034 and PMID:19696011 Esr1 Mouse diethylstilbestrol affects activity ISO Esr1 (Rattus norvegicus) 6480464 Diethylstilbestrol affects the activity of ESR1 protein CTD PMID:15746884 Esr1 Mouse diethylstilbestrol increases response to substance EXP 6480464 ESR1 protein mutant form results in increased susceptibility to Diethylstilbestrol and ESR1 results in increased susceptibility to Diethylstilbestrol CTD PMID:22989549 and PMID:9290700 Esr1 Mouse diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of ESR1 mRNA and Diethylstilbestrol results in increased expression of ESR1 protein CTD PMID:15070830 more ... Esr1 Mouse diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of ESR1 mRNA and Diethylstilbestrol results in decreased expression of ESR1 protein CTD PMID:14871586 more ... Esr1 Mouse diethylstilbestrol multiple interactions EXP 6480464 [[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR1 protein more ... CTD PMID:10965916 more ... Esr1 Mouse diethylstilbestrol affects binding ISO ESR1 (Homo sapiens) 6480464 [Diethylstilbestrol binds to ESR1 protein] which binds to NCOA2 protein and Diethylstilbestrol binds to ESR1 protein CTD PMID:10964929 more ... Esr1 Mouse digitoxin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Digitoxin binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse diheptyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 diheptyl phthalate analog binds to ESR1 protein CTD PMID:15464722 Esr1 Mouse diisobutyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 diisobutyl phthalate binds to and results in increased activity of ESR1 protein more ... CTD PMID:15840436 more ... Esr1 Mouse diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESR1 mRNA CTD PMID:28013214 Esr1 Mouse diisobutyl phthalate increases activity ISO ESR1 (Homo sapiens) 6480464 diisobutyl phthalate results in increased activity of ESR1 protein CTD PMID:28571686 Esr1 Mouse Diisodecyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR1 protein CTD PMID:35739755 and PMID:37364641 Esr1 Mouse diisononyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein more ... CTD PMID:28013214 more ... Esr1 Mouse diisononyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 diisononyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28571686 Esr1 Mouse dimethoate decreases activity ISO ESR1 (Homo sapiens) 6480464 Dimethoate results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse dimethoate increases expression EXP 6480464 Dimethoate results in increased expression of ESR1 protein CTD PMID:23943137 Esr1 Mouse dimethomorph multiple interactions ISO ESR1 (Homo sapiens) 6480464 dimethomorph binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse dimethyl sulfoxide multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 Esr1 Mouse dimethylarsinic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of ESR1 mRNA CTD PMID:23192986 Esr1 Mouse diniconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 diniconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse dioscin increases expression EXP 6480464 dioscin results in increased expression of ESR1 protein CTD PMID:24742230 Esr1 Mouse dioscin increases expression ISO ESR1 (Homo sapiens) 6480464 dioscin results in increased expression of ESR1 protein CTD PMID:24742230 Esr1 Mouse dioscin multiple interactions EXP 6480464 fulvestrant inhibits the reaction [dioscin results in increased expression of ESR1 protein] CTD PMID:24742230 Esr1 Mouse dioxygen affects expression EXP 6480464 Oxygen deficiency affects the expression of ESR1 protein and Oxygen deficiency affects the expression of ESR1 protein alternative form CTD PMID:28859903 Esr1 Mouse dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of ESR1 mRNA CTD PMID:24846829 Esr1 Mouse dioxygen multiple interactions EXP 6480464 [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased expression of ESR1 protein more ... CTD PMID:24846829 and PMID:28859903 Esr1 Mouse dioxygen multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA more ... CTD PMID:24333797 and PMID:37606869 Esr1 Mouse dioxygen decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Oxygen deficiency results in decreased expression of ESR1 mRNA and Oxygen deficiency results in decreased expression of ESR1 protein CTD PMID:24333797 Esr1 Mouse dioxygen affects expression ISO Esr1 (Rattus norvegicus) 6480464 Oxygen deficiency affects the expression of ESR1 mRNA and Oxygen deficiency affects the expression of ESR1 protein CTD PMID:24333797 Esr1 Mouse dioxygen increases expression ISO Esr1 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of ESR1 mRNA and Oxygen deficiency results in increased expression of ESR1 protein CTD PMID:15927375 and PMID:18457817 Esr1 Mouse dioxygen multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Diethylhexyl Phthalate] results in decreased expression of ESR1 protein more ... CTD PMID:19578757 and PMID:30851587 Esr1 Mouse dioxygen decreases expression ISO ESR1 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of ESR1 mRNA and Oxygen deficiency results in decreased expression of ESR1 protein CTD PMID:19578757 and PMID:30851587 Esr1 Mouse dipentyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 di-n-pentyl phthalate analog binds to ESR1 protein and di-n-pentyl phthalate binds to ESR1 protein CTD PMID:15464722 and PMID:20822795 Esr1 Mouse dipentyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein more ... CTD PMID:15840436 more ... Esr1 Mouse Diphenolic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 diphenolic acid binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse diphenylmethanol multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzohydrol binds to and results in increased activity of ESR1 protein CTD PMID:16079615 Esr1 Mouse dipropyl phthalate affects binding ISO ESR1 (Homo sapiens) 6480464 di-n-propylphthalate analog binds to ESR1 protein CTD PMID:15464722 Esr1 Mouse diquat decreases expression EXP 6480464 Diquat results in decreased expression of ESR1 mRNA CTD PMID:36851058 Esr1 Mouse disodium selenite multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA] CTD PMID:30526071 Esr1 Mouse disulfiram multiple interactions ISO ESR1 (Homo sapiens) 6480464 Disulfiram binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse Dithiopyr multiple interactions ISO ESR1 (Homo sapiens) 6480464 dithiopyr binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse diuron multiple interactions ISO ESR1 (Homo sapiens) 6480464 Diuron binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse dobutamine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Dobutamine binds to and results in increased activity of ESR1 protein CTD PMID:24928891 Esr1 Mouse dodecylamine multiple interactions ISO ESR1 (Homo sapiens) 6480464 dodecylamine binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse doxorubicin increases activity ISO ESR1 (Homo sapiens) 6480464 Doxorubicin results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse doxorubicin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Quercetin affects the reaction [Doxorubicin affects the expression of ESR1 mRNA] and Vitamin E affects the reaction [Doxorubicin affects the expression of ESR1 mRNA] CTD PMID:32810592 Esr1 Mouse doxorubicin affects expression ISO Esr1 (Rattus norvegicus) 6480464 Doxorubicin affects the expression of ESR1 mRNA CTD PMID:32810592 Esr1 Mouse doxorubicin increases expression ISO ESR1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of ESR1 mRNA and Doxorubicin results in increased expression of ESR1 protein CTD PMID:19351845 Esr1 Mouse doxorubicin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA more ... CTD PMID:16322899 more ... Esr1 Mouse doxorubicin decreases activity ISO ESR1 (Homo sapiens) 6480464 Doxorubicin results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse dronedarone multiple interactions ISO ESR1 (Homo sapiens) 6480464 dronedarone binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse elemental selenium multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA] CTD PMID:30526071 Esr1 Mouse emamectin benzoate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [cypermethrin co-treated with emamectin benzoate] results in decreased expression of ESR1 mRNA and [cypermethrin co-treated with emamectin benzoate] results in decreased expression of ESR1 protein CTD PMID:37984602 Esr1 Mouse emetine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Emetine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse emodin increases activity ISO ESR1 (Homo sapiens) 6480464 Emodin results in increased activity of ESR1 protein CTD PMID:19161236 Esr1 Mouse endosulfan multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:10397250 more ... Esr1 Mouse endosulfan affects methylation ISO Esr1 (Rattus norvegicus) 6480464 Endosulfan affects the methylation of ESR1 promoter alternative form CTD PMID:28559116 Esr1 Mouse endosulfan decreases methylation ISO Esr1 (Rattus norvegicus) 6480464 Endosulfan results in decreased methylation of ESR1 promoter CTD PMID:28559116 Esr1 Mouse endosulfan increases activity ISO ESR1 (Homo sapiens) 6480464 Endosulfan results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:26139245 Esr1 Mouse endosulfan increases activity ISO Esr1 (Rattus norvegicus) 6480464 Endosulfan results in increased activity of ESR1 protein CTD PMID:17174995 and PMID:9860891 Esr1 Mouse endosulfan multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [o and p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR1 protein CTD PMID:9860891 Esr1 Mouse endosulfan increases expression ISO Esr1 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of ESR1 mRNA more ... CTD PMID:22198180 more ... Esr1 Mouse endosulfan affects binding EXP 6480464 Endosulfan binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse endosulfan affects binding ISO ESR1 (Homo sapiens) 6480464 Endosulfan binds to ESR1 protein CTD PMID:14579009 and PMID:19913605 Esr1 Mouse endosulfan decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of ESR1 mRNA and Endosulfan results in decreased expression of ESR1 protein CTD PMID:18790044 and PMID:29391264 Esr1 Mouse endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ESR1 protein CTD PMID:21278053 Esr1 Mouse endosulfan multiple interactions EXP 6480464 Endosulfan inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:21278053 Esr1 Mouse endosulfan decreases expression ISO ESR1 (Homo sapiens) 6480464 Endosulfan results in decreased expression of ESR1 mRNA CTD PMID:15261991 and PMID:28673560 Esr1 Mouse endrin increases activity ISO ESR1 (Homo sapiens) 6480464 Endrin results in increased activity of ESR1 protein CTD PMID:15064155 more ... Esr1 Mouse endrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Endrin binds to and results in increased activity of ESR1 protein CTD PMID:16626760 Esr1 Mouse enilconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 enilconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse enzacamene increases activity ISO ESR1 (Homo sapiens) 6480464 enzacamene results in increased activity of ESR1 protein CTD PMID:12765243 Esr1 Mouse enzacamene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA CTD PMID:34383603 Esr1 Mouse enzacamene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 enzacamene results in decreased expression of ESR1 mRNA CTD PMID:19150460 Esr1 Mouse enzacamene multiple interactions ISO ESR1 (Homo sapiens) 6480464 enzacamene binds to and results in increased activity of ESR1 protein CTD PMID:16079615 and PMID:24004914 Esr1 Mouse EPN increases activity ISO ESR1 (Homo sapiens) 6480464 Phenylphosphonothioic Acid and 2-Ethyl 2-(4-Nitrophenyl) Ester results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of ESR1 mRNA CTD PMID:35436446 Esr1 Mouse equilin increases activity ISO Esr1 (Rattus norvegicus) 6480464 Equilin results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse equilin affects binding ISO ESR1 (Homo sapiens) 6480464 Equilin binds to ESR1 protein CTD PMID:21138273 Esr1 Mouse equilin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Equilin binds to and results in increased activity of ESR1 protein and Fulvestrant inhibits the reaction [Equilin results in increased activity of ESR1 protein] CTD PMID:22562034 and PMID:33049310 Esr1 Mouse equilin increases activity ISO ESR1 (Homo sapiens) 6480464 Equilin results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse equol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [afimoxifene binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Equol more ... CTD PMID:15876408 more ... Esr1 Mouse equol increases activity ISO ESR1 (Homo sapiens) 6480464 Equol results in increased activity of ESR1 protein CTD PMID:16118406 Esr1 Mouse equol affects binding ISO ESR1 (Homo sapiens) 6480464 Equol binds to ESR1 protein CTD PMID:15993745 more ... Esr1 Mouse equol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Equol results in increased expression of ESR1 mRNA and Equol results in increased expression of ESR1 mRNA alternative form CTD PMID:23220561 Esr1 Mouse erlotinib hydrochloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 Erlotinib Hydrochloride affects the expression of and affects the phosphorylation of ESR1 protein CTD PMID:34463000 Esr1 Mouse Estradiol dipropionate multiple interactions EXP 6480464 [estradiol dipropionate co-treated with Butyrates] results in decreased expression of ESR1 protein and [estradiol dipropionate co-treated with trichostatin A] results in decreased expression of ESR1 protein CTD PMID:15930180 Esr1 Mouse estriol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estriol binds to and results in increased activity of ESR1 protein more ... CTD PMID:12127041 more ... Esr1 Mouse estriol affects binding ISO ESR1 (Homo sapiens) 6480464 Estriol binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse estriol increases activity ISO ESR1 (Homo sapiens) 6480464 Estriol results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse estriol affects binding EXP 6480464 Estriol binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse estriol affects binding ISO Esr1 (Rattus norvegicus) 6480464 Estriol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse estriol affects localization EXP 6480464 Estriol affects the localization of ESR1 protein CTD PMID:20950447 Esr1 Mouse estriol increases expression ISO ESR1 (Homo sapiens) 6480464 Estriol results in increased expression of ESR1 mRNA CTD PMID:19820872 and PMID:29783106 Esr1 Mouse estrogen increases expression ISO Esr1 (Rattus norvegicus) 152177689 estrogen increases expression of Esr1 mRNA in rat uterus RGD Esr1 Mouse estrone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estrone binds to and results in increased activity of ESR1 protein more ... CTD PMID:12127041 more ... Esr1 Mouse estrone increases expression ISO ESR1 (Homo sapiens) 6480464 Estrone results in increased expression of ESR1 mRNA CTD PMID:29783106 Esr1 Mouse estrone affects binding ISO ESR1 (Homo sapiens) 6480464 Estrone binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse estrone increases activity ISO ESR1 (Homo sapiens) 6480464 Estrone results in increased activity of ESR1 protein CTD PMID:11331656 and PMID:22562034 Esr1 Mouse estrone affects binding EXP 6480464 Estrone binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse estrone increases activity ISO Esr1 (Rattus norvegicus) 6480464 Estrone results in increased activity of ESR1 protein CTD PMID:11750080 Esr1 Mouse Ethalfluralin multiple interactions ISO ESR1 (Homo sapiens) 6480464 ethafluralin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse ethanol increases expression ISO ESR1 (Homo sapiens) 6480464 Ethanol results in increased expression of ESR1 protein CTD PMID:15659783 Esr1 Mouse ethanol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein] CTD PMID:32198086 Esr1 Mouse ethanol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Ethanol results in increased expression of ESR1 mRNA and Ethanol results in increased expression of ESR1 protein CTD PMID:23591044 and PMID:29769550 Esr1 Mouse ethanol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Ethanol results in decreased expression of ESR1 mRNA and Ethanol results in decreased expression of ESR1 protein CTD PMID:23273579 and PMID:23591044 Esr1 Mouse ethanol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Ethanol co-treated with Melatonin] results in decreased expression of ESR1 protein and [Ethanol co-treated with Melatonin] results in increased expression of ESR1 protein CTD PMID:23591044 Esr1 Mouse ethion increases activity ISO ESR1 (Homo sapiens) 6480464 ethion results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse ethisterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Ethisterone results in increased expression of GREB1 mRNA] and ESR1 protein affects the reaction [Ethisterone results in increased expression of SGK1 mRNA] CTD PMID:33405908 Esr1 Mouse Ethyl cinnamate multiple interactions ISO ESR1 (Homo sapiens) 6480464 ethyl cinnamate binds to and results in increased activity of ESR1 protein CTD PMID:16079615 Esr1 Mouse ethyl myristate multiple interactions ISO ESR1 (Homo sapiens) 6480464 ethyl myristate binds to and results in decreased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse ethylenediaminetetraacetic acid increases expression ISO ESR1 (Homo sapiens) 6480464 Edetic Acid results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse Ethylenethiourea multiple interactions EXP 6480464 Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of ESR1 mRNA] CTD PMID:34571837 Esr1 Mouse ethylparaben increases activity ISO ESR1 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse ethylparaben affects binding ISO ESR1 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate binds to ESR1 protein CTD PMID:11193391 Esr1 Mouse ethylparaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate binds to and results in increased activity of ESR1 protein CTD PMID:23567241 and PMID:29162470 Esr1 Mouse ethylparaben affects binding ISO Esr1 (Rattus norvegicus) 6480464 ethyl-p-hydroxybenzoate binds to ESR1 protein CTD PMID:20132880 Esr1 Mouse etofenprox decreases activity ISO Esr1 (Rattus norvegicus) 6480464 ethofenprox results in decreased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse etoposide multiple interactions ISO ESR1 (Homo sapiens) 6480464 Etoposide inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse eugenol affects binding ISO ESR1 (Homo sapiens) 6480464 Eugenol binds to ESR1 protein CTD PMID:12495555 Esr1 Mouse eugenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Eugenol inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12495555 Esr1 Mouse exemestane multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 more ... CTD PMID:18677558 and PMID:25752796 Esr1 Mouse farrerol increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 farrerol results in increased phosphorylation of ESR1 protein CTD PMID:17323972 Esr1 Mouse felodipine increases activity ISO ESR1 (Homo sapiens) 6480464 Felodipine results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse fenamiphos multiple interactions ISO ESR1 (Homo sapiens) 6480464 fenamiphos binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse fenarimol increases activity ISO ESR1 (Homo sapiens) 6480464 fenarimol results in increased activity of ESR1 protein CTD PMID:15064155 more ... Esr1 Mouse fenarimol decreases expression ISO ESR1 (Homo sapiens) 6480464 fenarimol results in decreased expression of ESR1 mRNA CTD PMID:15261991 Esr1 Mouse fenarimol affects binding ISO ESR1 (Homo sapiens) 6480464 fenarimol binds to ESR1 protein CTD PMID:15253041 Esr1 Mouse fenarimol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Chlorpyrifos co-treated with fenarimol co-treated with Estradiol] results in increased activity of ESR1 protein more ... CTD PMID:10789375 more ... Esr1 Mouse fenbuconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 fenbuconazole binds to and results in increased activity of ESR1 protein CTD PMID:16626760 Esr1 Mouse fenhexamid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [fludioxonil co-treated with N-(2 more ... CTD PMID:23052036 more ... Esr1 Mouse fenhexamid increases activity ISO ESR1 (Homo sapiens) 6480464 N-(2 and 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased activity of ESR1 protein CTD PMID:20143881 and PMID:26812056 Esr1 Mouse fenhexamid decreases expression ISO ESR1 (Homo sapiens) 6480464 N-(2 and 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of ESR1 mRNA CTD PMID:23052036 Esr1 Mouse fenitrothion multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fenitrothion binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse fenofibrate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein] more ... CTD PMID:29134746 Esr1 Mouse fenthion multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fenthion binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse fenvalerate increases activity ISO ESR1 (Homo sapiens) 6480464 fenvalerate results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse fenvalerate increases expression ISO Esr1 (Rattus norvegicus) 6480464 fenvalerate results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse fenvalerate increases expression ISO ESR1 (Homo sapiens) 6480464 fenvalerate results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse fenvalerate affects binding ISO Esr1 (Rattus norvegicus) 6480464 fenvalerate binds to ESR1 protein CTD PMID:12396874 Esr1 Mouse fenvalerate increases activity ISO Esr1 (Rattus norvegicus) 6480464 fenvalerate results in increased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse fenvalerate multiple interactions ISO ESR1 (Homo sapiens) 6480464 fenvalerate binds to and results in increased activity of ESR1 protein CTD PMID:16626760 Esr1 Mouse finasteride multiple interactions ISO ESR1 (Homo sapiens) 6480464 Finasteride binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse finasteride affects expression ISO Esr1 (Rattus norvegicus) 6480464 Finasteride affects the expression of ESR1 mRNA CTD PMID:30768126 Esr1 Mouse finasteride multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Finasteride inhibits the reaction [Testosterone results in increased expression of ESR1 protein] CTD PMID:27866977 Esr1 Mouse fingolimod hydrochloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fingolimod Hydrochloride inhibits the reaction [Estradiol results in increased expression of ESR1 protein] CTD PMID:29654831 Esr1 Mouse fipronil decreases expression ISO ESR1 (Homo sapiens) 6480464 fipronil results in decreased expression of ESR1 mRNA CTD PMID:27091632 and PMID:38050659 Esr1 Mouse fipronil multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 fipronil inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28531659 Esr1 Mouse fipronil multiple interactions ISO ESR1 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in decreased expression of ESR1 mRNA CTD PMID:27091632 Esr1 Mouse flavonoids affects binding ISO ESR1 (Homo sapiens) 6480464 Flavonoids analog binds to ESR1 protein CTD PMID:16892383 Esr1 Mouse flavonoids multiple interactions EXP 6480464 Flavonoids inhibits the reaction [bisphenol A results in decreased expression of ESR1 mRNA] CTD PMID:36966614 Esr1 Mouse fluazifop-butyl increases activity ISO ESR1 (Homo sapiens) 6480464 fluazifop-butyl results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse flucythrinate increases activity ISO ESR1 (Homo sapiens) 6480464 flucythrinate results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse fludioxonil multiple interactions ISO ESR1 (Homo sapiens) 6480464 [fludioxonil co-treated with Estradiol] results in decreased expression of ESR1 mRNA more ... CTD PMID:23052036 more ... Esr1 Mouse fludioxonil increases activity ISO ESR1 (Homo sapiens) 6480464 fludioxonil results in increased activity of ESR1 protein CTD PMID:20143881 and PMID:26812056 Esr1 Mouse fludioxonil decreases expression ISO ESR1 (Homo sapiens) 6480464 fludioxonil results in decreased expression of ESR1 mRNA CTD PMID:23052036 Esr1 Mouse flumethrin increases expression ISO ESR1 (Homo sapiens) 6480464 flumethrin results in increased expression of ESR1 mRNA CTD PMID:34142587 Esr1 Mouse Flumetralin multiple interactions ISO ESR1 (Homo sapiens) 6480464 flumetralin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse fluoranthene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein more ... CTD PMID:12441364 more ... Esr1 Mouse fluoranthene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 fluoranthene results in decreased expression of ESR1 protein CTD PMID:18634860 Esr1 Mouse fluoxastrobin multiple interactions ISO ESR1 (Homo sapiens) 6480464 fluoxastrobin inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse flutamide increases expression ISO Esr1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of ESR1 mRNA and Flutamide results in increased expression of ESR1 protein CTD PMID:11748029 and PMID:16003321 Esr1 Mouse flutamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 Flutamide binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse flutamide increases expression ISO ESR1 (Homo sapiens) 6480464 Flutamide results in increased expression of ESR1 mRNA CTD PMID:21128595 Esr1 Mouse flutolanil decreases expression ISO ESR1 (Homo sapiens) 6480464 flutolanil results in decreased expression of ESR1 protein CTD PMID:17904202 Esr1 Mouse flutolanil multiple interactions ISO ESR1 (Homo sapiens) 6480464 flutolanil binds to and results in increased activity of ESR1 protein CTD PMID:17904202 Esr1 Mouse folic acid affects expression EXP 6480464 Folic Acid affects the expression of ESR1 mRNA CTD PMID:25629700 Esr1 Mouse formaldehyde increases expression ISO ESR1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of ESR1 mRNA CTD PMID:27905399 Esr1 Mouse formestane increases expression ISO ESR1 (Homo sapiens) 6480464 formestane metabolite results in increased expression of ESR1 mRNA CTD PMID:29702199 Esr1 Mouse formononetin affects binding ISO ESR1 (Homo sapiens) 6480464 formononetin binds to ESR1 protein CTD PMID:16773531 Esr1 Mouse formononetin multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with formononetin] results in increased expression of ESR1 protein CTD PMID:37269934 Esr1 Mouse formononetin multiple interactions ISO ESR1 (Homo sapiens) 6480464 formononetin binds to and results in increased activity of ESR1 protein CTD PMID:16076101 and PMID:9751507 Esr1 Mouse fructose decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Fructose results in decreased expression of ESR1 protein CTD PMID:31661889 Esr1 Mouse fructose multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 bisphenol A promotes the reaction [Fructose results in decreased expression of ESR1 protein] and Fructose promotes the reaction [bisphenol A results in decreased expression of ESR1 protein] CTD PMID:31661889 Esr1 Mouse fulvestrant multiple interactions ISO ESR1 (Homo sapiens) 6480464 5-OH-BDE-47 promotes the reaction [Fulvestrant results in decreased expression of ESR1 protein] more ... CTD PMID:11174852 more ... Esr1 Mouse fulvestrant decreases activity ISO Esr1 (Rattus norvegicus) 6480464 Fulvestrant results in decreased activity of ESR1 protein CTD PMID:35803362 Esr1 Mouse fulvestrant increases expression EXP 6480464 Fulvestrant results in increased expression of ESR1 mRNA CTD PMID:30061528 Esr1 Mouse fulvestrant increases expression ISO ESR1 (Homo sapiens) 6480464 Fulvestrant results in increased expression of ESR1 mRNA CTD PMID:26877835 more ... Esr1 Mouse fulvestrant increases ubiquitination ISO ESR1 (Homo sapiens) 6480464 fulvestrant results in increased ubiquitination of ESR1 protein CTD PMID:12612060 Esr1 Mouse fulvestrant decreases expression ISO Esr1 (Rattus norvegicus) 6480464 fulvestrant results in decreased expression of ESR1 protein CTD PMID:18634860 Esr1 Mouse fulvestrant affects response to substance EXP 6480464 ESR1 protein mutant form affects the susceptibility to fulvestrant CTD PMID:21873215 Esr1 Mouse fulvestrant affects binding ISO Esr1 (Rattus norvegicus) 6480464 fulvestrant binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse fulvestrant affects binding EXP 6480464 fulvestrant binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse fulvestrant decreases expression ISO ESR1 (Homo sapiens) 6480464 Fulvestrant results in decreased expression of ESR1 more ... CTD PMID:11867264 more ... Esr1 Mouse fulvestrant affects binding ISO ESR1 (Homo sapiens) 6480464 fulvestrant binds to ESR1 protein CTD PMID:11518614 more ... Esr1 Mouse fulvestrant affects activity ISO ESR1 (Homo sapiens) 6480464 fulvestrant affects the activity of ESR1 protein CTD PMID:15950373 more ... Esr1 Mouse fulvestrant affects expression ISO ESR1 (Homo sapiens) 6480464 fulvestrant affects the expression of ESR1 mRNA CTD PMID:20543978 Esr1 Mouse fulvestrant increases degradation ISO Esr1 (Rattus norvegicus) 6480464 fulvestrant results in increased degradation of ESR1 protein CTD PMID:20419096 Esr1 Mouse fulvestrant multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 1 more ... CTD PMID:18511507 more ... Esr1 Mouse fulvestrant decreases expression EXP 6480464 fulvestrant results in decreased expression of ESR1 protein CTD PMID:12927369 Esr1 Mouse fulvestrant multiple interactions EXP 6480464 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA] more ... CTD PMID:12927369 more ... Esr1 Mouse fulvestrant increases degradation ISO ESR1 (Homo sapiens) 6480464 fulvestrant results in increased degradation of ESR1 mRNA and fulvestrant results in increased degradation of ESR1 protein CTD PMID:15899841 more ... Esr1 Mouse fulvestrant decreases activity ISO ESR1 (Homo sapiens) 6480464 fulvestrant results in decreased activity of ESR1 protein CTD PMID:16010691 Esr1 Mouse furan increases expression EXP 6480464 furan results in increased expression of ESR1 mRNA CTD PMID:24183702 Esr1 Mouse Fusarielin A increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to fusarielin A and ESR1 protein results in increased susceptibility to fusarielin A analog CTD PMID:22982765 Esr1 Mouse galangin increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 galangin results in increased phosphorylation of ESR1 protein CTD PMID:17323972 Esr1 Mouse galaxolide multiple interactions ISO ESR1 (Homo sapiens) 6480464 galaxolide binds to and results in increased activity of ESR1 protein CTD PMID:17762842 Esr1 Mouse gamma-aminobutyric acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Estradiol inhibits the reaction [Potassium results in increased secretion of gamma-Aminobutyric Acid]] CTD PMID:19211896 Esr1 Mouse gamma-hexachlorocyclohexane multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA more ... CTD PMID:14579009 more ... Esr1 Mouse gamma-hexachlorocyclohexane increases activity ISO ESR1 (Homo sapiens) 6480464 Hexachlorocyclohexane results in increased activity of ESR1 protein CTD PMID:26022396 and PMID:26139245 Esr1 Mouse gamma-hexachlorocyclohexane affects binding ISO ESR1 (Homo sapiens) 6480464 Hexachlorocyclohexane binds to ESR1 protein CTD PMID:14579009 and PMID:15253041 Esr1 Mouse gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of ESR1 protein CTD PMID:21278053 Esr1 Mouse gamma-hexachlorocyclohexane multiple interactions EXP 6480464 Hexachlorocyclohexane binds to and results in increased activity of ESR1 protein CTD PMID:20209442 Esr1 Mouse gamma-tocopherol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA] and [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 Esr1 Mouse gefitinib decreases phosphorylation ISO ESR1 (Homo sapiens) 6480464 gefitinib results in decreased phosphorylation of ESR1 protein CTD PMID:16261397 Esr1 Mouse geldanamycin multiple interactions ISO ESR1 (Homo sapiens) 6480464 geldanamycin inhibits the reaction [Estradiol binds to ESR1 protein] more ... CTD PMID:11448926 and PMID:16037132 Esr1 Mouse geldanamycin decreases expression ISO ESR1 (Homo sapiens) 6480464 geldanamycin results in decreased expression of ESR1 protein CTD PMID:11448926 and PMID:24211270 Esr1 Mouse geldanamycin decreases stability ISO ESR1 (Homo sapiens) 6480464 geldanamycin results in decreased stability of ESR1 protein CTD PMID:11448926 Esr1 Mouse geldanamycin increases degradation ISO ESR1 (Homo sapiens) 6480464 geldanamycin results in increased degradation of ESR1 protein CTD PMID:16037132 Esr1 Mouse gemcitabine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Gemcitabine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse Geniposidic acid decreases expression ISO Esr1 (Rattus norvegicus) 6480464 geniposidic acid results in decreased expression of ESR1 protein CTD PMID:29899696 Esr1 Mouse genistein affects response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein affects the susceptibility to Genistein CTD PMID:19400946 Esr1 Mouse genistein increases activity ISO ESR1 (Homo sapiens) 6480464 Genistein results in increased activity of ESR1 protein CTD PMID:11485867 more ... Esr1 Mouse genistein increases expression EXP 6480464 Genistein results in increased expression of ESR1 mRNA CTD PMID:18281260 more ... Esr1 Mouse genistein decreases expression EXP 6480464 Genistein results in decreased expression of ESR1 mRNA CTD PMID:11880592 more ... Esr1 Mouse genistein decreases expression ISO ESR1 (Homo sapiens) 6480464 Genistein results in decreased expression of ESR1 mRNA and Genistein results in decreased expression of ESR1 protein CTD PMID:11502892 more ... Esr1 Mouse genistein affects binding ISO Esr1 (Rattus norvegicus) 6480464 Genistein binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse genistein affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to Genistein CTD PMID:21624456 Esr1 Mouse genistein affects binding EXP 6480464 Genistein binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse genistein affects expression ISO Esr1 (Rattus norvegicus) 6480464 Genistein affects the expression of ESR1 protein CTD PMID:11731036 Esr1 Mouse genistein increases activity EXP 6480464 Genistein results in increased activity of ESR1 protein CTD PMID:19495926 Esr1 Mouse genistein multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Genistein results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 Esr1 Mouse genistein increases expression ISO ESR1 (Homo sapiens) 6480464 Genistein results in increased expression of ESR1 mRNA CTD PMID:11922773 and PMID:15968319 Esr1 Mouse genistein affects binding ISO ESR1 (Homo sapiens) 6480464 [Genistein binds to ESR1 protein] which binds to NCOA2 protein and Genistein binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse genistein affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to Genistein CTD PMID:17275032 Esr1 Mouse genistein multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of ESR1 mRNA more ... CTD PMID:11896288 more ... Esr1 Mouse genistein increases expression ISO Esr1 (Rattus norvegicus) 6480464 Genistein results in increased expression of ESR1 mRNA CTD PMID:16443925 and PMID:17341692 Esr1 Mouse genistein increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 Genistein results in increased phosphorylation of ESR1 protein CTD PMID:17323972 Esr1 Mouse genistein increases activity ISO Esr1 (Rattus norvegicus) 6480464 Genistein results in increased activity of ESR1 protein CTD PMID:11750080 Esr1 Mouse genistein decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Genistein results in decreased expression of ESR1 more ... CTD PMID:12929590 more ... Esr1 Mouse genistein multiple interactions ISO ESR1 (Homo sapiens) 6480464 2 more ... CTD PMID:10397250 more ... Esr1 Mouse geranial affects binding ISO ESR1 (Homo sapiens) 6480464 citral binds to ESR1 protein CTD PMID:12495555 Esr1 Mouse geranial multiple interactions ISO ESR1 (Homo sapiens) 6480464 citral inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12495555 Esr1 Mouse geraniol affects binding ISO ESR1 (Homo sapiens) 6480464 geraniol binds to ESR1 protein CTD PMID:12495555 Esr1 Mouse geraniol multiple interactions ISO ESR1 (Homo sapiens) 6480464 geraniol inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12495555 Esr1 Mouse gestodene multiple interactions ISO ESR1 (Homo sapiens) 6480464 Gestodene binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse ginsenoside Re multiple interactions ISO ESR1 (Homo sapiens) 6480464 ginsenoside Re binds to and affects the activity of ESR1 protein CTD PMID:16985185 Esr1 Mouse glucose decreases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in decreased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse glucose increases abundance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased abundance of Glucose CTD PMID:31520823 Esr1 Mouse glucose multiple interactions ISO ESR1 (Homo sapiens) 6480464 Endosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose] CTD PMID:31520823 Esr1 Mouse glucose increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of ESR1 protein CTD PMID:23690508 Esr1 Mouse glucose multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA more ... CTD PMID:18426865 and PMID:37606869 Esr1 Mouse glucose increases expression ISO ESR1 (Homo sapiens) 6480464 Glucose results in increased expression of ESR1 mRNA CTD PMID:16621514 Esr1 Mouse Glutathione ethyl ester multiple interactions ISO ESR1 (Homo sapiens) 6480464 S-ethyl glutathione inhibits the reaction [Benzo(a)pyrene results in decreased expression of ESR1 protein] CTD PMID:26149760 Esr1 Mouse glyceollin affects binding ISO ESR1 (Homo sapiens) 6480464 glyceollin binds to ESR1 protein CTD PMID:19797619 Esr1 Mouse glyceollin multiple interactions ISO ESR1 (Homo sapiens) 6480464 glyceollin inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:19797619 Esr1 Mouse glycitein multiple interactions ISO ESR1 (Homo sapiens) 6480464 glycitein inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 Esr1 Mouse glycitein affects binding ISO ESR1 (Homo sapiens) 6480464 glycitein binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse glyphosate affects splicing ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate affects the splicing of ESR1 mRNA CTD PMID:30447247 Esr1 Mouse glyphosate affects expression ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate affects the expression of ESR1 protein CTD PMID:27463640 Esr1 Mouse glyphosate increases methylation ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate results in increased methylation of ESR1 promoter CTD PMID:30447247 Esr1 Mouse glyphosate increases expression ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate results in increased expression of ESR1 mRNA more ... CTD PMID:27287056 more ... Esr1 Mouse glyphosate increases expression ISO ESR1 (Homo sapiens) 6480464 Glyphosate results in increased expression of ESR1 mRNA and Glyphosate results in increased expression of ESR1 protein CTD PMID:23756170 and PMID:29890199 Esr1 Mouse glyphosate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Glyphosate results in increased methylation of ESR1 promoter] which affects the splicing of ESR1 mRNA and Fulvestrant inhibits the reaction [Glyphosate results in increased expression of ESR1 protein] CTD PMID:30447247 and PMID:34906888 Esr1 Mouse glyphosate increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to Glyphosate CTD PMID:29890199 Esr1 Mouse glyphosate increases activity ISO ESR1 (Homo sapiens) 6480464 Glyphosate results in increased activity of ESR1 protein CTD PMID:28711546 Esr1 Mouse glyphosate affects expression ISO ESR1 (Homo sapiens) 6480464 Glyphosate affects the expression of ESR1 mRNA CTD PMID:35457321 Esr1 Mouse glyphosate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [afimoxifene results in decreased susceptibility to Glyphosate] which results in increased expression of ESR1 protein modified form more ... CTD PMID:19539684 more ... Esr1 Mouse glyphosate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate results in decreased expression of ESR1 mRNA and Glyphosate results in decreased expression of ESR1 protein CTD PMID:27463640 more ... Esr1 Mouse glyphosate decreases methylation ISO Esr1 (Rattus norvegicus) 6480464 Glyphosate results in decreased methylation of ESR1 promoter CTD PMID:30391669 Esr1 Mouse gold atom decreases expression ISO ESR1 (Homo sapiens) 6480464 Gold analog results in decreased expression of ESR1 mRNA CTD PMID:36057382 Esr1 Mouse gold(0) decreases expression ISO ESR1 (Homo sapiens) 6480464 Gold analog results in decreased expression of ESR1 mRNA CTD PMID:36057382 Esr1 Mouse gonadorelin multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gonadotropin-Releasing Hormone results in decreased expression of ESR1 protein] and Gonadotropin-Releasing Hormone results in increased ubiquitination of and results in increased degradation of and results in decreased expression of ESR1 protein CTD PMID:16055746 Esr1 Mouse Goserelin decreases expression ISO ESR1 (Homo sapiens) 6480464 Goserelin results in decreased expression of ESR1 protein CTD PMID:16973256 Esr1 Mouse heptachlor increases activity ISO ESR1 (Homo sapiens) 6480464 Heptachlor results in increased activity of ESR1 protein CTD PMID:26022396 and PMID:26139245 Esr1 Mouse heptachlor multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Heptachlor inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28531659 Esr1 Mouse heptachlor increases expression ISO Esr1 (Rattus norvegicus) 6480464 Heptachlor results in increased expression of ESR1 CTD PMID:27240701 Esr1 Mouse Heptachlor epoxide increases activity ISO ESR1 (Homo sapiens) 6480464 Heptachlor Epoxide results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse herbicide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Glyphosate co-treated with Herbicides] results in decreased activity of ESR1 protein CTD PMID:19539684 Esr1 Mouse herbicide decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Herbicides results in decreased expression of ESR1 mRNA CTD PMID:32360609 Esr1 Mouse herbicide increases expression ISO Esr1 (Rattus norvegicus) 6480464 Herbicides results in increased expression of ESR1 protein CTD PMID:29746933 and PMID:32640336 Esr1 Mouse hexachlorobenzene multiple interactions ISO ESR1 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of ESR1 protein] more ... CTD PMID:19879930 more ... Esr1 Mouse hexachlorobenzene increases expression ISO ESR1 (Homo sapiens) 6480464 Hexachlorobenzene results in increased expression of ESR1 protein CTD PMID:35181438 Esr1 Mouse hexachlorobenzene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Hexachlorobenzene results in decreased expression of ESR1 protein CTD PMID:29277037 Esr1 Mouse hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of ESR1 protein CTD PMID:28923513 Esr1 Mouse hexachlorobenzene increases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased phosphorylation of ESR1 protein CTD PMID:22245120 Esr1 Mouse hexachlorobenzene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Hexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein] more ... CTD PMID:22245120 Esr1 Mouse hexachlorobenzene increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Hexachlorobenzene results in increased phosphorylation of ESR1 protein CTD PMID:19879930 and PMID:35181438 Esr1 Mouse hexachlorobenzene decreases expression ISO ESR1 (Homo sapiens) 6480464 Hexachlorobenzene results in decreased expression of ESR1 protein CTD PMID:19879930 Esr1 Mouse hexachlorophene affects binding ISO ESR1 (Homo sapiens) 6480464 Hexachlorophene binds to ESR1 protein CTD PMID:15081572 Esr1 Mouse hexachlorophene multiple interactions ISO ESR1 (Homo sapiens) 6480464 Hexachlorophene inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:15081572 Esr1 Mouse hexestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 afimoxifene inhibits the reaction [Hexestrol binds to and results in increased activity of ESR1 protein] more ... CTD PMID:18976723 more ... Esr1 Mouse hexestrol affects binding ISO ESR1 (Homo sapiens) 6480464 Hexestrol binds to ESR1 protein CTD PMID:19233257 and PMID:20074635 Esr1 Mouse hydralazine decreases methylation ISO ESR1 (Homo sapiens) 6480464 Hydralazine results in decreased methylation of ESR1 promoter CTD PMID:15862127 Esr1 Mouse hydralazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Hydralazine inhibits the reaction [3-methylquinoline results in increased activity of ESR1 protein] and Hydralazine inhibits the reaction [8-methylquinoline results in increased activity of ESR1 protein] CTD PMID:30896932 Esr1 Mouse hydralazine increases expression ISO ESR1 (Homo sapiens) 6480464 Hydralazine results in increased expression of ESR1 mRNA CTD PMID:15862127 Esr1 Mouse hydrazine decreases expression EXP 6480464 hydrazine results in decreased expression of ESR1 mRNA CTD PMID:15282401 Esr1 Mouse hydrogen peroxide increases expression ISO ESR1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse hydrogen peroxide multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Estradiol inhibits the reaction [Hydrogen Peroxide affects the localization of AIFM1 protein]] CTD PMID:25280774 Esr1 Mouse hydrogen peroxide affects expression ISO ESR1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of ESR1 protein CTD PMID:21179406 Esr1 Mouse hydrogencarbonate multiple interactions EXP 6480464 [4 more ... CTD PMID:18499763 Esr1 Mouse hydroquinone decreases expression ISO ESR1 (Homo sapiens) 6480464 hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 Esr1 Mouse hydroxyflutamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 hydroxyflutamide binds to and results in increased activity of ESR1 protein and hydroxyflutamide inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of ESR1 protein] CTD PMID:18275596 and PMID:33049310 Esr1 Mouse ibuprofen decreases expression EXP 6480464 Ibuprofen results in decreased expression of ESR1 mRNA CTD PMID:37453669 Esr1 Mouse icariside II multiple interactions ISO ESR1 (Homo sapiens) 6480464 baohuoside I binds to and results in increased degradation of ESR1 protein more ... CTD PMID:35802278 Esr1 Mouse Icaritin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Fulvestrant binds to and results in decreased activity of ESR1 protein] inhibits the reaction [icaritin results in increased activity of ESR1 protein] CTD PMID:22613215 Esr1 Mouse Icaritin increases activity ISO ESR1 (Homo sapiens) 6480464 icaritin results in increased activity of ESR1 protein CTD PMID:22613215 Esr1 Mouse ICI-164384 affects binding EXP 6480464 ICI 164384 binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse ICI-164384 multiple interactions ISO ESR1 (Homo sapiens) 6480464 [ICI 164384 binds to and results in increased activity of ESR1 protein] which results in increased expression of HSPB1 mRNA and ICI 164384 binds to and results in increased activity of ESR1 protein CTD PMID:11174852 Esr1 Mouse ICI-164384 affects binding ISO ESR1 (Homo sapiens) 6480464 ICI 164384 binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse idarubicin decreases activity ISO ESR1 (Homo sapiens) 6480464 Idarubicin results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse idarubicin increases activity ISO ESR1 (Homo sapiens) 6480464 Idarubicin results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse imidacloprid increases expression ISO ESR1 (Homo sapiens) 6480464 imidacloprid results in increased expression of ESR1 mRNA CTD PMID:35457321 Esr1 Mouse imidazoles multiple interactions ISO ESR1 (Homo sapiens) 6480464 Imidazoles analog binds to and affects the activity of ESR1 protein CTD PMID:17352461 Esr1 Mouse Indeno[1,2,3-cd]pyrene affects binding ISO ESR1 (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:32251684 Esr1 Mouse indole-3-methanol decreases expression ISO ESR1 (Homo sapiens) 6480464 indole-3-carbinol analog results in decreased expression of ESR1 protein CTD PMID:20570586 Esr1 Mouse indole-3-methanol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 indole-3-carbinol inhibits the reaction [bisphenol A results in increased expression of ESR1 protein] CTD PMID:24257414 Esr1 Mouse indole-3-methanol multiple interactions ISO ESR1 (Homo sapiens) 6480464 BRCA1 protein promotes the reaction [indole-3-carbinol inhibits the reaction [Estradiol results in increased activity of ESR1 protein]] and indole-3-carbinol inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:11110848 and PMID:16434996 Esr1 Mouse indoles multiple interactions EXP 6480464 Indoles analog binds to and affects the activity of ESR1 protein CTD PMID:15911274 Esr1 Mouse inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ESR1 mRNA CTD PMID:36331819 Esr1 Mouse iodoacetic acid decreases expression EXP 6480464 Iodoacetic Acid results in decreased expression of ESR1 mRNA CTD PMID:31693920 Esr1 Mouse ipriflavone multiple interactions ISO ESR1 (Homo sapiens) 6480464 ipriflavone binds to and results in increased activity of ESR1 protein CTD PMID:9751507 Esr1 Mouse iprodione multiple interactions ISO ESR1 (Homo sapiens) 6480464 iprodione binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse Isobutylparaben affects binding ISO ESR1 (Homo sapiens) 6480464 isobutyl-4-hydroxybenzoate binds to ESR1 protein and isobutylparaben metabolite binds to ESR1 protein CTD PMID:11193391 and PMID:29945225 Esr1 Mouse Isobutylparaben affects binding ISO Esr1 (Rattus norvegicus) 6480464 isobutylparaben binds to ESR1 protein CTD PMID:20132880 Esr1 Mouse Isobutylparaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 isobutylparaben binds to and results in increased activity of ESR1 protein CTD PMID:23567241 Esr1 Mouse isofenphos increases activity ISO ESR1 (Homo sapiens) 6480464 isofenphos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse isoflavones affects expression ISO Esr1 (Rattus norvegicus) 6480464 Isoflavones affects the expression of ESR1 CTD PMID:21112483 Esr1 Mouse isoflavones increases expression ISO Esr1 (Rattus norvegicus) 6480464 Isoflavones results in increased expression of ESR1 mRNA CTD PMID:35963426 Esr1 Mouse isoflavones multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Genistein co-treated with Isoflavones] results in decreased expression of ESR1 mRNA CTD PMID:20381596 Esr1 Mouse isoflavones decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Isoflavones results in decreased expression of ESR1 protein CTD PMID:22155228 Esr1 Mouse isoflavones increases activity ISO ESR1 (Homo sapiens) 6480464 Isoflavones results in increased activity of ESR1 protein CTD PMID:11485867 Esr1 Mouse Isopropylparaben decreases expression ISO Esr1 (Rattus norvegicus) 6480464 isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 mRNA and isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 protein CTD PMID:19654335 Esr1 Mouse Isopropylparaben multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 mRNA] and Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 protein] CTD PMID:19654335 Esr1 Mouse Isopropylparaben affects binding ISO ESR1 (Homo sapiens) 6480464 isopropyl 4-hydroxybenzoate binds to ESR1 protein CTD PMID:11193391 Esr1 Mouse isoprothiolane multiple interactions ISO ESR1 (Homo sapiens) 6480464 isoprothiolane binds to and results in increased activity of ESR1 protein CTD PMID:17904202 Esr1 Mouse isoprothiolane decreases expression ISO ESR1 (Homo sapiens) 6480464 isoprothiolane results in decreased expression of ESR1 protein CTD PMID:17904202 Esr1 Mouse isorhamnetin affects binding ISO ESR1 (Homo sapiens) 6480464 3-methylquercetin binds to ESR1 protein CTD PMID:14706564 Esr1 Mouse Isoxanthohumol increases activity ISO ESR1 (Homo sapiens) 6480464 isoxanthohumol results in increased activity of ESR1 protein CTD PMID:12623674 Esr1 Mouse ivermectin multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Ivermectin results in increased expression of EGR3 mRNA] more ... CTD PMID:33405908 Esr1 Mouse ivermectin increases expression ISO ESR1 (Homo sapiens) 6480464 Ivermectin results in increased expression of ESR1 CTD PMID:26078298 Esr1 Mouse ivermectin increases expression EXP 6480464 Ivermectin results in increased expression of ESR1 CTD PMID:26078298 Esr1 Mouse kaempferol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein inhibits the reaction [kaempferol results in increased expression of CCN5 mRNA] more ... CTD PMID:14579009 more ... Esr1 Mouse kaempferol affects binding ISO Esr1 (Rattus norvegicus) 6480464 kaempferol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse kaempferol affects binding EXP 6480464 kaempferol binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse kaempferol affects binding ISO ESR1 (Homo sapiens) 6480464 kaempferol binds to ESR1 protein CTD PMID:14579009 more ... Esr1 Mouse kaempferol increases expression ISO ESR1 (Homo sapiens) 6480464 kaempferol results in increased expression of ESR1 mRNA CTD PMID:15182386 Esr1 Mouse kaempferol increases activity ISO ESR1 (Homo sapiens) 6480464 kaempferol results in increased activity of ESR1 protein CTD PMID:16118406 Esr1 Mouse ketoconazole decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Ketoconazole results in decreased expression of ESR1 mRNA CTD PMID:37077353 Esr1 Mouse L-1,4-dithiothreitol multiple interactions ISO ESR1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Dithiothreitol results in increased activity of ESR1 protein] and Tamoxifen inhibits the reaction [Dithiothreitol results in increased activity of ESR1 protein] CTD PMID:22403704 Esr1 Mouse L-ascorbic acid multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA] CTD PMID:18602937 Esr1 Mouse lacidipine increases activity ISO ESR1 (Homo sapiens) 6480464 lacidipine results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse lapatinib decreases activity ISO ESR1 (Homo sapiens) 6480464 lapatinib results in decreased activity of ESR1 protein CTD PMID:15665275 Esr1 Mouse lapatinib multiple interactions ISO ESR1 (Homo sapiens) 6480464 [lapatinib co-treated with afimoxifene] results in decreased activity of ESR1 protein CTD PMID:15665275 Esr1 Mouse Laurolactam multiple interactions ISO ESR1 (Homo sapiens) 6480464 laurolactam binds to and results in decreased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse lead(II) chloride affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to lead chloride CTD PMID:12746304 Esr1 Mouse lead(II) chloride decreases expression ISO ESR1 (Homo sapiens) 6480464 lead chloride results in decreased expression of ESR1 mRNA and lead chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse lead(II) chloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estradiol promotes the reaction [lead chloride results in decreased expression of ESR1 mRNA] more ... CTD PMID:12746304 Esr1 Mouse lead(II) chloride increases activity ISO ESR1 (Homo sapiens) 6480464 lead chloride results in increased activity of ESR1 protein CTD PMID:12746304 Esr1 Mouse leptomycin B multiple interactions ISO ESR1 (Homo sapiens) 6480464 leptomycin B inhibits the reaction [Estradiol results in increased degradation of ESR1 protein] CTD PMID:15899841 Esr1 Mouse leptophos increases activity ISO ESR1 (Homo sapiens) 6480464 Leptophos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse lercanidipine decreases activity ISO ESR1 (Homo sapiens) 6480464 lercanidipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse letrozole multiple interactions EXP 6480464 diacerein inhibits the reaction [Letrozole results in decreased expression of ESR1 mRNA] CTD PMID:37030623 Esr1 Mouse letrozole decreases expression EXP 6480464 Letrozole results in decreased expression of ESR1 mRNA CTD PMID:37030623 Esr1 Mouse levonorgestrel multiple interactions ISO ESR1 (Homo sapiens) 6480464 Levonorgestrel binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse lidocaine increases expression ISO ESR1 (Homo sapiens) 6480464 Lidocaine results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse lignin affects binding ISO Esr1 (Rattus norvegicus) 6480464 Lignin analog binds to ESR1 protein CTD PMID:27420082 Esr1 Mouse linalool increases activity ISO ESR1 (Homo sapiens) 6480464 linalool results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse linalyl acetate increases activity ISO ESR1 (Homo sapiens) 6480464 linalyl acetate results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse linalyl acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 Esr1 Mouse linuron multiple interactions ISO ESR1 (Homo sapiens) 6480464 Linuron binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse linuron multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA CTD PMID:34383603 Esr1 Mouse lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of ESR1 mRNA CTD PMID:12057914 Esr1 Mouse lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with formononetin] results in increased expression of ESR1 protein more ... CTD PMID:17158209 more ... Esr1 Mouse liquiritigenin increases activity ISO ESR1 (Homo sapiens) 6480464 liquiritigenin results in increased activity of ESR1 protein CTD PMID:28396216 Esr1 Mouse liraglutide increases expression ISO ESR1 (Homo sapiens) 6480464 Liraglutide results in increased expression of ESR1 mRNA and Liraglutide results in increased expression of ESR1 protein CTD PMID:34534549 Esr1 Mouse lithium chloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein more ... CTD PMID:16076840 and PMID:26990689 Esr1 Mouse loratadine increases expression EXP 6480464 Loratadine results in increased expression of ESR1 mRNA CTD PMID:16407038 Esr1 Mouse luteolin affects binding ISO ESR1 (Homo sapiens) 6480464 Luteolin binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse luteolin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Luteolin inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 Esr1 Mouse luteolin 7-O-beta-D-glucoside multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 more ... CTD PMID:31381935 Esr1 Mouse luteolin 7-O-beta-D-glucoside increases activity ISO ESR1 (Homo sapiens) 6480464 luteolin-7-glucoside results in increased activity of ESR1 protein CTD PMID:31381935 Esr1 Mouse LY 117018 affects binding ISO ESR1 (Homo sapiens) 6480464 LY 117018 binds to ESR1 protein CTD PMID:10397250 Esr1 Mouse LY294002 multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[FGF7 protein results in increased phosphorylation of AKT1 protein] which results in increased expression of ESR1 protein] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein affects the localization of ESR1 protein] CTD PMID:15947004 and PMID:19661335 Esr1 Mouse LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of ESR1] CTD PMID:26969072 Esr1 Mouse lycopene multiple interactions ISO ESR1 (Homo sapiens) 6480464 lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 Esr1 Mouse lycopene increases expression ISO ESR1 (Homo sapiens) 6480464 lycopene results in increased expression of ESR1 mRNA CTD PMID:16886892 Esr1 Mouse Lynestrenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Lynestrenol results in increased expression of GREB1 mRNA] CTD PMID:33405908 Esr1 Mouse M1 multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(((3 and 5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR1 protein CTD PMID:16750840 Esr1 Mouse malathion decreases activity ISO ESR1 (Homo sapiens) 6480464 Malathion results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse mancozeb decreases expression ISO ESR1 (Homo sapiens) 6480464 mancozeb results in decreased expression of ESR1 mRNA CTD PMID:33396126 Esr1 Mouse manganese atom increases expression ISO Esr1 (Rattus norvegicus) 6480464 Manganese results in increased expression of ESR1 protein CTD PMID:24845367 Esr1 Mouse manganese(0) increases expression ISO Esr1 (Rattus norvegicus) 6480464 Manganese results in increased expression of ESR1 protein CTD PMID:24845367 Esr1 Mouse manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of ESR1 protein CTD PMID:29183790 Esr1 Mouse manganese(II) chloride multiple interactions EXP 6480464 Estradiol inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein] and Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein] CTD PMID:29183790 Esr1 Mouse manidipine decreases activity ISO ESR1 (Homo sapiens) 6480464 manidipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse masoprocol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Masoprocol binds to and results in increased activity of ESR1 protein CTD PMID:19063592 Esr1 Mouse medroxyprogesterone acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] CTD PMID:20383792 Esr1 Mouse medroxyprogesterone acetate decreases expression ISO ESR1 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in decreased expression of ESR1 mRNA CTD PMID:20843944 Esr1 Mouse megestrol acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA] CTD PMID:33405908 Esr1 Mouse MeIQx multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:16533016 Esr1 Mouse MeIQx decreases activity ISO ESR1 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:16533016 Esr1 Mouse melatonin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Melatonin inhibits the reaction [bisphenol A promotes the reaction [ESR1 protein binds to POU5F1 promoter]] more ... CTD PMID:15813899 more ... Esr1 Mouse melatonin decreases expression ISO ESR1 (Homo sapiens) 6480464 Melatonin results in decreased expression of ESR1 mRNA CTD PMID:27551335 Esr1 Mouse melatonin decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Melatonin results in decreased expression of ESR1 mRNA and Melatonin results in decreased expression of ESR1 protein CTD PMID:16051031 and PMID:23591044 Esr1 Mouse melatonin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Ethanol co-treated with Melatonin] results in decreased expression of ESR1 protein more ... CTD PMID:16051031 and PMID:23591044 Esr1 Mouse melatonin decreases expression EXP 6480464 Melatonin results in decreased expression of ESR1 mRNA CTD PMID:16030176 Esr1 Mouse Melengestrol acetate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Melengestrol Acetate binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse menadione affects binding ISO ESR1 (Homo sapiens) 6480464 Vitamin K 3 binds to ESR1 protein CTD PMID:15081572 Esr1 Mouse menadione multiple interactions ISO ESR1 (Homo sapiens) 6480464 Vitamin K 3 inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:15081572 Esr1 Mouse mepanipyrim increases activity ISO Esr1 (Rattus norvegicus) 6480464 mepanipyrim results in increased activity of ESR1 protein CTD PMID:33352482 Esr1 Mouse mercaptopurine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of ESR1 mRNA CTD PMID:23358152 Esr1 Mouse mercury dichloride decreases expression ISO ESR1 (Homo sapiens) 6480464 Mercuric Chloride results in decreased expression of ESR1 mRNA and Mercuric Chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse mercury dichloride increases activity ISO ESR1 (Homo sapiens) 6480464 Mercuric Chloride results in increased activity of ESR1 protein CTD PMID:12746304 and PMID:17716812 Esr1 Mouse mercury dichloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 Mercuric Chloride inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12746304 Esr1 Mouse mercury dichloride affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to Mercuric Chloride CTD PMID:12746304 Esr1 Mouse mestranol increases activity ISO ESR1 (Homo sapiens) 6480464 Mestranol results in increased activity of ESR1 protein CTD PMID:12623674 Esr1 Mouse mestranol multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Mestranol results in increased expression of GREB1 mRNA] more ... CTD PMID:26865669 more ... Esr1 Mouse metconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 metconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse metformin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Metformin binds to and results in decreased activity of ESR1 protein more ... CTD PMID:22132214 and PMID:33049310 Esr1 Mouse metformin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Testosterone results in increased expression of ESR1 mRNA] CTD PMID:26492952 Esr1 Mouse methamphetamine increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 gene polymorphism results in increased susceptibility to Methamphetamine CTD PMID:19386276 Esr1 Mouse methanol increases expression ISO ESR1 (Homo sapiens) 6480464 Methanol results in increased expression of ESR1 protein CTD PMID:15659783 Esr1 Mouse methapyrilene affects methylation ISO ESR1 (Homo sapiens) 6480464 Methapyrilene affects the methylation of ESR1 intron CTD PMID:30157460 Esr1 Mouse methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of ESR1 mRNA CTD PMID:17408746 Esr1 Mouse methiocarb increases activity ISO ESR1 (Homo sapiens) 6480464 Methiocarb results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse methiocarb increases expression EXP 6480464 Methiocarb results in increased expression of ESR1 protein CTD PMID:19206145 Esr1 Mouse methomyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 Methomyl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 Esr1 Mouse methoxyacetic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 methoxyacetic acid inhibits the reaction [Estradiol results in increased activity of ESR1 protein] more ... CTD PMID:15103026 more ... Esr1 Mouse methoxyacetic acid decreases expression EXP 6480464 methoxyacetic acid results in decreased expression of ESR1 mRNA CTD PMID:20049119 Esr1 Mouse methoxyacetic acid decreases expression ISO ESR1 (Homo sapiens) 6480464 methoxyacetic acid results in decreased expression of ESR1 mRNA and methoxyacetic acid results in decreased expression of ESR1 protein CTD PMID:20049119 Esr1 Mouse methoxychlor multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:10579340 more ... Esr1 Mouse methoxychlor affects methylation ISO Esr1 (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of ESR1 gene CTD PMID:35440735 Esr1 Mouse methoxychlor increases activity ISO ESR1 (Homo sapiens) 6480464 Methoxychlor metabolite results in increased activity of ESR1 protein and Methoxychlor results in increased activity of ESR1 protein CTD PMID:11485867 more ... Esr1 Mouse methoxychlor increases methylation ISO Esr1 (Rattus norvegicus) 6480464 Methoxychlor results in increased methylation of ESR1 gene CTD PMID:23303685 Esr1 Mouse methoxychlor increases expression ISO Esr1 (Rattus norvegicus) 6480464 Methoxychlor results in increased expression of ESR1 mRNA CTD PMID:22016562 Esr1 Mouse methoxychlor affects binding ISO ESR1 (Homo sapiens) 6480464 Methoxychlor binds to ESR1 protein CTD PMID:14579009 more ... Esr1 Mouse methoxychlor decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Methoxychlor results in decreased expression of ESR1 mRNA CTD PMID:22285353 Esr1 Mouse methoxychlor affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 affects the susceptibility to Methoxychlor CTD PMID:22307313 Esr1 Mouse methoxychlor multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of ESR1 mRNA more ... CTD PMID:10579340 more ... Esr1 Mouse methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of ESR1 mRNA CTD PMID:8829249 Esr1 Mouse methoxychlor decreases expression EXP 6480464 Methoxychlor metabolite results in decreased expression of ESR1 mRNA and Methoxychlor results in decreased expression of ESR1 mRNA CTD PMID:11509743 and PMID:21252393 Esr1 Mouse methoxychlor increases response to substance EXP 6480464 ESR1 gene mutant form results in increased susceptibility to Methoxychlor and ESR1 protein results in increased susceptibility to Methoxychlor CTD PMID:16787999 and PMID:22306526 Esr1 Mouse methoxychlor multiple interactions EXP 6480464 [ESR1 gene mutant form results in increased susceptibility to Methoxychlor] which results in decreased expression of CASP3 protein more ... CTD PMID:11509743 more ... Esr1 Mouse methoxychlor affects metabolic processing EXP 6480464 ESR1 protein affects the metabolism of Methoxychlor CTD PMID:21252393 Esr1 Mouse methoxychlor increases expression ISO ESR1 (Homo sapiens) 6480464 Methoxychlor results in increased expression of ESR1 mRNA CTD PMID:11922773 Esr1 Mouse methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate decreases activity ISO ESR1 (Homo sapiens) 6480464 Nisoldipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse methyl laurate multiple interactions ISO ESR1 (Homo sapiens) 6480464 lauric acid methyl ester binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse methyl oleate multiple interactions ISO ESR1 (Homo sapiens) 6480464 methyl oleate binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse Methyl palmitate multiple interactions ISO ESR1 (Homo sapiens) 6480464 methyl palmitate binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse Methyl palmitate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 methyl palmitate inhibits the reaction [estradiol 3-benzoate results in increased expression of ESR1 protein] CTD PMID:32967526 Esr1 Mouse methyl salicylate affects expression ISO ESR1 (Homo sapiens) 6480464 methyl salicylate affects the expression of ESR1 mRNA CTD PMID:19527780 Esr1 Mouse methylarsonic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of ESR1 mRNA CTD PMID:23192986 Esr1 Mouse methylparaben decreases activity ISO ESR1 (Homo sapiens) 6480464 methylparaben results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse methylparaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 [bisphenol A co-treated with methylparaben co-treated with perfluorooctanoic acid] results in increased expression of and results in increased phosphorylation of ESR1 protein CTD PMID:29846718 Esr1 Mouse methylparaben increases expression ISO ESR1 (Homo sapiens) 6480464 methylparaben results in increased expression of ESR1 mRNA and methylparaben results in increased expression of ESR1 protein CTD PMID:25128701 Esr1 Mouse methylseleninic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 mRNA more ... CTD PMID:15833885 and PMID:16093440 Esr1 Mouse methylseleninic acid decreases expression ISO ESR1 (Homo sapiens) 6480464 methylselenic acid results in decreased expression of ESR1 mRNA and methylselenic acid results in decreased expression of ESR1 protein CTD PMID:15833885 more ... Esr1 Mouse methyltestosterone increases activity ISO Esr1 (Rattus norvegicus) 6480464 Methyltestosterone results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse methyltestosterone increases expression ISO ESR1 (Homo sapiens) 6480464 Methyltestosterone results in increased expression of ESR1 protein CTD PMID:38133387 Esr1 Mouse methyltestosterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Methyltestosterone binds to and results in increased activity of ESR1 protein more ... CTD PMID:23383871 more ... Esr1 Mouse metoclopramide multiple interactions EXP 6480464 [Metoclopramide co-treated with Estradiol] results in decreased expression of ESR1 protein CTD PMID:11786374 Esr1 Mouse metolachlor multiple interactions ISO ESR1 (Homo sapiens) 6480464 metolachlor binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse microcystin-LR affects expression EXP 6480464 cyanoginosin LR affects the expression of ESR1 mRNA CTD PMID:28189720 Esr1 Mouse microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of ESR1 protein CTD PMID:28189720 Esr1 Mouse mifepristone increases expression ISO Esr1 (Rattus norvegicus) 6480464 Mifepristone results in increased expression of ESR1 mRNA CTD PMID:20686183 Esr1 Mouse mirex multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse mithramycin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Plicamycin inhibits the reaction [afimoxifene promotes the reaction [ESR1 protein binds to CDH1 promoter]] CTD PMID:19593637 Esr1 Mouse Mitotane increases activity ISO ESR1 (Homo sapiens) 6480464 Mitotane results in increased activity of ESR1 protein CTD PMID:26139245 Esr1 Mouse Mitotane increases activity ISO Esr1 (Rattus norvegicus) 6480464 Mitotane results in increased activity of ESR1 protein CTD PMID:28531659 Esr1 Mouse Mitotane affects binding ISO ESR1 (Homo sapiens) 6480464 Mitotane binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse Mitotane multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Mitotane results in increased expression of SERPINA6 protein] more ... CTD PMID:14579009 more ... Esr1 Mouse Mitotane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Mitotane inhibits the reaction [Estradiol binds to ESR1 protein] and Mitotane inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:10580743 and PMID:28531659 Esr1 Mouse MK 571 multiple interactions ISO ESR1 (Homo sapiens) 6480464 verlukast binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse MK-2206 multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein alternative form promotes the reaction [MK 2206 inhibits the reaction [Estradiol results in decreased cleavage of CASP3 protein]] more ... CTD PMID:34724321 Esr1 Mouse molibresib decreases expression ISO ESR1 (Homo sapiens) 6480464 molibresib results in decreased expression of ESR1 mRNA CTD PMID:24874954 Esr1 Mouse mono(2-ethyl-5-oxohexyl) phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-oxohexyl)phthalate] which results in increased expression of ESR1 protein CTD PMID:38042133 Esr1 Mouse mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA and mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR1 protein CTD PMID:20209442 and PMID:31884101 Esr1 Mouse mono(2-ethylhexyl) phthalate increases expression ISO ESR1 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ESR1 mRNA and mono-(2-ethylhexyl)phthalate results in increased expression of ESR1 protein CTD PMID:33631300 and PMID:38042133 Esr1 Mouse mono(2-ethylhexyl) phthalate affects expression ISO ESR1 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate affects the expression of ESR1 mRNA CTD PMID:33631300 Esr1 Mouse mono(2-ethylhexyl) phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA more ... CTD PMID:33049310 more ... Esr1 Mouse mono(5-carboxy-2-ethylpentyl) phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of 2-ethyl-5-carboxypentyl phthalate] which results in decreased expression of ESR1 protein CTD PMID:38042133 Esr1 Mouse monobenzyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA and mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28571686 and PMID:35861251 Esr1 Mouse monobenzyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA CTD PMID:31884101 Esr1 Mouse Monobutylphthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA CTD PMID:35861251 Esr1 Mouse monoethyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA CTD PMID:31884101 Esr1 Mouse monoethyl phthalate multiple interactions ISO ESR1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA CTD PMID:35861251 Esr1 Mouse Moxestrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 moxestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] more ... CTD PMID:14617632 and PMID:9048584 Esr1 Mouse Moxestrol increases activity ISO ESR1 (Homo sapiens) 6480464 moxestrol results in increased activity of ESR1 protein CTD PMID:10875235 Esr1 Mouse mycophenolic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 Mycophenolic Acid binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse N,N'-diphenyl-1,4-phenylenediamine increases activity ISO Esr1 (Rattus norvegicus) 6480464 N and N'-diphenyl-4-phenylenediamine results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse N,N-bis(2-hydroxypropyl)nitrosamine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA] more ... CTD PMID:29050248 and PMID:34186418 Esr1 Mouse N,N-diethyl-m-toluamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in decreased expression of ESR1 mRNA CTD PMID:27091632 Esr1 Mouse N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:20360387 Esr1 Mouse N-acetyl-L-cysteine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of ESR1 protein] and Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA] CTD PMID:18829485 and PMID:26149760 Esr1 Mouse N-acetyl-L-cysteine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ESR1 protein] CTD PMID:32402895 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein] more ... CTD PMID:12612060 more ... Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases ubiquitination EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of ESR1 protein CTD PMID:29428397 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ESR1 mRNA CTD PMID:31806706 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Esr1 (Rattus norvegicus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR1 protein CTD PMID:16564422 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein] CTD PMID:20419096 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR1 protein CTD PMID:14702340 and PMID:31806706 Esr1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [PTK2B protein affects the ubiquitination of ESR1 protein] more ... CTD PMID:16055746 and PMID:29428397 Esr1 Mouse N-Desmethyltamoxifen multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [[Tamoxifen co-treated with N-desmethyltamoxifen co-treated with afimoxifene] results in increased stability of ESR1 protein] and [Tamoxifen co-treated with N-desmethyltamoxifen co-treated with afimoxifene] results in increased stability of ESR1 protein CTD PMID:19244106 Esr1 Mouse N-hydroxy-PhIP multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-hydroxyamino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:16533016 Esr1 Mouse N-hydroxy-PhIP decreases activity ISO ESR1 (Homo sapiens) 6480464 2-hydroxyamino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased activity of ESR1 protein CTD PMID:16533016 Esr1 Mouse N-methyl-4-phenylpyridinium multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 more ... CTD PMID:31381935 Esr1 Mouse N-methyl-4-phenylpyridinium decreases phosphorylation ISO ESR1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein CTD PMID:31381935 Esr1 Mouse N-methyl-4-phenylpyridinium affects localization EXP 6480464 1-Methyl-4-phenylpyridinium affects the localization of ESR1 protein CTD PMID:27037955 Esr1 Mouse N-methyl-N-nitrosourea multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA] more ... CTD PMID:16891317 more ... Esr1 Mouse N-methyl-N-nitrosourea decreases phosphorylation ISO Esr1 (Rattus norvegicus) 6480464 Methylnitrosourea results in decreased phosphorylation of ESR1 protein CTD PMID:22245120 Esr1 Mouse N-methyl-N-nitrosourea increases response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein results in increased susceptibility to Methylnitrosourea CTD PMID:15528971 Esr1 Mouse N-nitrosodiethylamine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA more ... CTD PMID:34186418 and PMID:36608567 Esr1 Mouse N-nitrosodiethylamine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of ESR1 protein CTD PMID:36608567 Esr1 Mouse n-propyl gallate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Propyl Gallate binds to and results in decreased activity of ESR1 protein CTD PMID:19063592 Esr1 Mouse n-propyl gallate increases activity ISO ESR1 (Homo sapiens) 6480464 Propyl Gallate results in increased activity of ESR1 protein CTD PMID:16756374 Esr1 Mouse Nafoxidine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Nafoxidine inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] CTD PMID:9048584 Esr1 Mouse nandrolone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Nandrolone binds to and results in increased activity of ESR1 protein CTD PMID:29162470 Esr1 Mouse Nandrolone decanoate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Nandrolone Decanoate results in decreased expression of ESR1 protein CTD PMID:33984419 Esr1 Mouse naphthalene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein and AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein] CTD PMID:30980910 Esr1 Mouse napropamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 devrinol binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse naringin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 fulvestrant inhibits the reaction [naringin results in increased expression of ESR1 mRNA] CTD PMID:23596885 Esr1 Mouse naringin increases expression ISO Esr1 (Rattus norvegicus) 6480464 naringin results in increased expression of ESR1 mRNA CTD PMID:23596885 Esr1 Mouse nebivolol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Nebivolol binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse nicardipine decreases activity ISO ESR1 (Homo sapiens) 6480464 Nicardipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse nickel dichloride affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to nickel chloride CTD PMID:12746304 Esr1 Mouse nickel dichloride decreases expression ISO ESR1 (Homo sapiens) 6480464 nickel chloride results in decreased expression of ESR1 mRNA and nickel chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse nickel dichloride multiple interactions ISO ESR1 (Homo sapiens) 6480464 nickel chloride binds to and results in increased activity of ESR1 protein and nickel chloride inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12746304 Esr1 Mouse nicotine decreases expression ISO ESR1 (Homo sapiens) 6480464 Nicotine results in decreased expression of ESR1 mRNA CTD PMID:27552315 Esr1 Mouse nifedipine increases activity ISO ESR1 (Homo sapiens) 6480464 Nifedipine results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse nilotinib decreases expression EXP 6480464 nilotinib results in decreased expression of ESR1 protein CTD PMID:32771489 Esr1 Mouse nilutamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 nilutamide binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse nisoldipine decreases activity ISO ESR1 (Homo sapiens) 6480464 Nisoldipine results in decreased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse nitrazepam multiple interactions ISO ESR1 (Homo sapiens) 6480464 Nitrazepam binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse nitric oxide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [resveratrol promotes the reaction [ESR1 protein binds to CAV1 protein binds to SRC protein]] which results in increased abundance of Nitric Oxide CTD PMID:18296501 Esr1 Mouse nitrofen affects binding ISO ESR1 (Homo sapiens) 6480464 nitrofen binds to ESR1 protein CTD PMID:15253041 Esr1 Mouse nitrofen multiple interactions ISO ESR1 (Homo sapiens) 6480464 nitrofen binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse nitroprusside multiple interactions EXP 6480464 ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Nitroprusside] and ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine co-treated with Nitroprusside] CTD PMID:17158209 Esr1 Mouse Nonylphenol decreases expression EXP 6480464 nonylphenol analog results in decreased expression of ESR1 mRNA and nonylphenol analog results in decreased expression of ESR1 protein CTD PMID:25242005 Esr1 Mouse Nonylphenol affects localization ISO ESR1 (Homo sapiens) 6480464 nonylphenol affects the localization of ESR1 protein CTD PMID:27260121 Esr1 Mouse Nonylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 nonylphenol analog results in increased activity of ESR1 protein and nonylphenol results in increased activity of ESR1 protein CTD PMID:14975756 more ... Esr1 Mouse Nonylphenol decreases expression ISO ESR1 (Homo sapiens) 6480464 nonylphenol results in decreased expression of ESR1 mRNA and nonylphenol results in decreased expression of ESR1 protein CTD PMID:14709801 and PMID:14754635 Esr1 Mouse Nonylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 nonylphenol analog binds to ESR1 protein more ... CTD PMID:10492897 more ... Esr1 Mouse Nonylphenol affects activity ISO ESR1 (Homo sapiens) 6480464 nonylphenol affects the activity of ESR1 protein CTD PMID:18635651 Esr1 Mouse Nonylphenol increases expression ISO Esr1 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of ESR1 mRNA and nonylphenol results in increased expression of ESR1 protein CTD PMID:11731036 more ... Esr1 Mouse Nonylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 nonylphenol results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse Nonylphenol affects binding ISO Esr1 (Rattus norvegicus) 6480464 nonylphenol binds to ESR1 protein CTD PMID:11086226 Esr1 Mouse Nonylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 [nonylphenol binds to ESR1 protein] which results in increased activity of ALPL protein more ... CTD PMID:12650720 more ... Esr1 Mouse Nonylphenol increases expression ISO ESR1 (Homo sapiens) 6480464 nonylphenol results in increased expression of ESR1 mRNA CTD PMID:26224478 Esr1 Mouse Nonylphenol increases expression EXP 6480464 nonylphenol analog results in increased expression of ESR1 mRNA and nonylphenol analog results in increased expression of ESR1 protein CTD PMID:25242005 Esr1 Mouse norethisterone increases activity ISO Esr1 (Rattus norvegicus) 6480464 Norethindrone results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse norethisterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Norethindrone results in increased expression of GREB1 mRNA] more ... CTD PMID:25012808 more ... Esr1 Mouse Norethynodrel multiple interactions ISO ESR1 (Homo sapiens) 6480464 Norethynodrel binds to and results in increased activity of ESR1 protein CTD PMID:20362049 more ... Esr1 Mouse Norethynodrel affects binding ISO ESR1 (Homo sapiens) 6480464 Norethynodrel binds to ESR1 protein CTD PMID:20074635 Esr1 Mouse norgestrel increases activity ISO Esr1 (Rattus norvegicus) 6480464 Norgestrel results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse norgestrel multiple interactions ISO ESR1 (Homo sapiens) 6480464 Norgestrel binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse notoginsenoside R1 increases expression EXP 6480464 notoginsenoside R1 results in increased expression of ESR1 protein CTD PMID:23170834 Esr1 Mouse notoginsenoside R1 multiple interactions EXP 6480464 [1 more ... CTD PMID:23170834 Esr1 Mouse notoginsenoside R1 multiple interactions ISO ESR1 (Homo sapiens) 6480464 notoginsenoside R1 results in increased phosphorylation of and results in increased activity of ESR1 protein CTD PMID:26362186 Esr1 Mouse notoginsenoside R1 increases expression ISO Esr1 (Rattus norvegicus) 6480464 notoginsenoside R1 results in increased expression of ESR1 more ... CTD PMID:24720662 and PMID:25738436 Esr1 Mouse O-Desmethylangolensin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estradiol affects the reaction [O-desmethylangolensin affects the activity of ESR1 protein] CTD PMID:16965913 Esr1 Mouse octadecanoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 stearic acid binds to and results in increased activity of ESR1 protein CTD PMID:27633901 Esr1 Mouse octamethylcyclotetrasiloxane multiple interactions ISO ESR1 (Homo sapiens) 6480464 octamethylcyclotetrasiloxane binds to and results in increased activity of ESR1 protein CTD PMID:17175556 Esr1 Mouse octocrylene multiple interactions ISO ESR1 (Homo sapiens) 6480464 octocrylene binds to and results in increased activity of ESR1 protein CTD PMID:16079615 Esr1 Mouse okadaic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Okadaic Acid results in increased degradation of ESR1 mRNA] more ... CTD PMID:15965230 and PMID:19800873 Esr1 Mouse okadaic acid decreases expression ISO ESR1 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of ESR1 protein CTD PMID:15965230 Esr1 Mouse ormeloxifene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Estradiol co-treated with ormeloxifene] promotes the reaction [NCOR1 protein binds to ESR1 protein] more ... CTD PMID:19460436 Esr1 Mouse oryzalin multiple interactions ISO ESR1 (Homo sapiens) 6480464 oryzalin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse ospemifene decreases expression ISO ESR1 (Homo sapiens) 6480464 Ospemifene results in decreased expression of ESR1 mRNA and Ospemifene results in decreased expression of ESR1 protein CTD PMID:27163517 Esr1 Mouse ospemifene multiple interactions ISO ESR1 (Homo sapiens) 6480464 Ospemifene inhibits the reaction [Estradiol results in increased expression of ESR1 protein] CTD PMID:27163517 Esr1 Mouse Oxadiazon multiple interactions ISO ESR1 (Homo sapiens) 6480464 oxadiazon binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse oxamyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 oxamyl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 Esr1 Mouse oxidopamine increases expression ISO Esr1 (Rattus norvegicus) 6480464 Oxidopamine results in increased expression of ESR1 mRNA CTD PMID:12486162 Esr1 Mouse oxybenzone decreases expression ISO Esr1 (Rattus norvegicus) 6480464 oxybenzone results in decreased expression of ESR1 mRNA and oxybenzone results in decreased expression of ESR1 protein CTD PMID:15458797 and PMID:30099065 Esr1 Mouse oxybenzone increases expression EXP 6480464 oxybenzone results in increased expression of ESR1 mRNA CTD PMID:32946892 Esr1 Mouse oxybenzone increases expression ISO Esr1 (Rattus norvegicus) 6480464 oxybenzone results in increased expression of ESR1 mRNA CTD PMID:30099065 Esr1 Mouse oxybenzone multiple interactions ISO ESR1 (Homo sapiens) 6480464 oxybenzone binds to and results in increased activity of ESR1 protein and oxybenzone promotes the reaction [ESR1 protein binds to ESR1 protein] CTD PMID:16079615 more ... Esr1 Mouse oxymetholone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Oxymetholone binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse ozone multiple interactions EXP 6480464 [[Ozone results in increased oxidation of Particulate Matter] which results in increased chemical synthesis of Aerosols] which results in decreased expression of ESR1 mRNA more ... CTD PMID:25361045 and PMID:34911549 Esr1 Mouse ozone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of ESR1 mRNA CTD PMID:35430440 Esr1 Mouse p-tert-Amylphenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol binds to and results in increased activity of ESR1 protein more ... CTD PMID:10964929 more ... Esr1 Mouse p-tert-Amylphenol affects binding ISO Esr1 (Rattus norvegicus) 6480464 4-tert-octylphenol binds to ESR1 protein CTD PMID:11086226 Esr1 Mouse p-tert-Amylphenol affects binding EXP 6480464 4-tert-octylphenol binds to ESR1 protein CTD PMID:11162928 Esr1 Mouse p-tert-Amylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of ESR1 mRNA and 4-tert-octylphenol results in decreased expression of ESR1 protein CTD PMID:23557686 and PMID:30061528 Esr1 Mouse p-tert-Amylphenol increases activity ISO Esr1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in increased activity of ESR1 protein CTD PMID:11750080 and PMID:12504345 Esr1 Mouse p-tert-Amylphenol increases expression ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased expression of ESR1 mRNA CTD PMID:12737316 Esr1 Mouse p-tert-Amylphenol increases activity ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased activity of ESR1 protein mutant form CTD PMID:17141713 Esr1 Mouse p-tert-Amylphenol multiple interactions EXP 6480464 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA] and Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of ESR1 mRNA] CTD PMID:23557686 and PMID:30061528 Esr1 Mouse p-tert-Amylphenol affects binding ISO ESR1 (Homo sapiens) 6480464 4-tert-octylphenol binds to ESR1 protein and p-tert-amylphenol binds to ESR1 protein CTD PMID:10964929 more ... Esr1 Mouse paclitaxel multiple interactions ISO ESR1 (Homo sapiens) 6480464 alitretinoin inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] more ... CTD PMID:15283693 and PMID:19340624 Esr1 Mouse paclitaxel increases expression ISO ESR1 (Homo sapiens) 6480464 Paclitaxel results in increased expression of ESR1 mRNA CTD PMID:19340624 Esr1 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of ESR1 mRNA CTD PMID:17562736 Esr1 Mouse paracetamol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of ESR1 mRNA CTD PMID:33387578 Esr1 Mouse paracetamol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA CTD PMID:34383603 Esr1 Mouse paracetamol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Acetaminophen inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to ESR1 protein]] CTD PMID:15713566 Esr1 Mouse paraoxon decreases activity ISO ESR1 (Homo sapiens) 6480464 Paraoxon results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse paraquat decreases activity ISO Esr1 (Rattus norvegicus) 6480464 Paraquat results in decreased activity of ESR1 protein CTD PMID:31715309 Esr1 Mouse paraquat decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Paraquat results in decreased expression of ESR1 mRNA CTD PMID:32680482 Esr1 Mouse parathion decreases activity ISO ESR1 (Homo sapiens) 6480464 Parathion results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse parathion-methyl multiple interactions ISO ESR1 (Homo sapiens) 6480464 Methyl Parathion binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse pendimethalin increases activity ISO ESR1 (Homo sapiens) 6480464 pendimethalin results in increased activity of ESR1 protein CTD PMID:15064155 and PMID:20143881 Esr1 Mouse pendimethalin multiple interactions ISO ESR1 (Homo sapiens) 6480464 pendimethalin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse pentachlorophenol multiple interactions ISO ESR1 (Homo sapiens) 6480464 Pentachlorophenol binds to and results in decreased activity of ESR1 protein and Pentachlorophenol inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:15081572 and PMID:16626760 Esr1 Mouse pentachlorophenol affects binding ISO ESR1 (Homo sapiens) 6480464 Pentachlorophenol binds to ESR1 protein CTD PMID:15081572 Esr1 Mouse perfluorobutanesulfonic acid affects binding ISO ESR1 (Homo sapiens) 6480464 perfluorobutanesulfonic acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 Esr1 Mouse perfluorobutyric acid affects binding ISO ESR1 (Homo sapiens) 6480464 perfluorobutyric acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 Esr1 Mouse perfluorodecanoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 perfluorodecanoic acid binds to and results in increased activity of ESR1 protein CTD PMID:21163906 Esr1 Mouse perfluorododecanoic acid decreases expression ISO Esr1 (Rattus norvegicus) 6480464 perfluorododecanoic acid results in decreased expression of ESR1 mRNA CTD PMID:19429406 Esr1 Mouse perfluorohexanesulfonic acid affects binding ISO ESR1 (Homo sapiens) 6480464 perfluorohexanesulfonic acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 Esr1 Mouse perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of ESR1 mRNA CTD PMID:37995155 Esr1 Mouse perfluorononanoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid binds to and results in increased activity of ESR1 protein CTD PMID:21163906 Esr1 Mouse perfluorooctane-1-sulfonic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [[Hydrocarbons more ... CTD PMID:21163906 and PMID:31923581 Esr1 Mouse perfluorooctane-1-sulfonic acid affects binding ISO ESR1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 Esr1 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ESR1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ESR1 mRNA CTD PMID:36331819 Esr1 Mouse perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ESR1 protein CTD PMID:34303733 Esr1 Mouse perfluorooctane-1-sulfonic acid increases expression ISO ESR1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of ESR1 mRNA CTD PMID:22269386 Esr1 Mouse perfluorooctanoic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 [bisphenol A co-treated with methylparaben co-treated with perfluorooctanoic acid] results in increased expression of and results in increased phosphorylation of ESR1 protein more ... CTD PMID:21163906 more ... Esr1 Mouse perfluorooctanoic acid increases expression ISO Esr1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of ESR1 mRNA CTD PMID:35163327 Esr1 Mouse perfluorooctanoic acid decreases expression ISO ESR1 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of ESR1 mRNA CTD PMID:25868421 Esr1 Mouse perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of ESR1 protein CTD PMID:22414604 Esr1 Mouse perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ESR1 protein CTD PMID:20118188 Esr1 Mouse perfluoropentanoic acid affects binding ISO ESR1 (Homo sapiens) 6480464 perfluoropentanoic acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 Esr1 Mouse perfluoroundecanoic acid increases activity ISO ESR1 (Homo sapiens) 6480464 perfluoroundecanoic acid results in increased activity of ESR1 protein CTD PMID:21163906 Esr1 Mouse permethrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Permethrin binds to and results in increased activity of ESR1 protein and Permethrin metabolite binds to and results in increased activity of ESR1 protein CTD PMID:16395479 and PMID:33049310 Esr1 Mouse permethrin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Permethrin co-treated with Estradiol] results in decreased expression of ESR1 CTD PMID:25048945 Esr1 Mouse permethrin increases expression ISO ESR1 (Homo sapiens) 6480464 Permethrin results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse permethrin increases expression ISO Esr1 (Rattus norvegicus) 6480464 Permethrin results in increased expression of ESR1 mRNA CTD PMID:24388911 Esr1 Mouse permethrin increases expression EXP 6480464 Permethrin metabolite results in increased expression of ESR1 mRNA CTD PMID:20574910 Esr1 Mouse permethrin decreases expression ISO ESR1 (Homo sapiens) 6480464 Permethrin results in decreased expression of ESR1 mRNA CTD PMID:20397420 Esr1 Mouse permethrin affects binding ISO ESR1 (Homo sapiens) 6480464 Permethrin binds to ESR1 protein and Permethrin metabolite binds to ESR1 protein CTD PMID:20574910 and PMID:32278787 Esr1 Mouse permethrin increases activity ISO Esr1 (Rattus norvegicus) 6480464 Permethrin results in increased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse permethrin decreases activity ISO Esr1 (Rattus norvegicus) 6480464 Permethrin results in decreased activity of ESR1 protein CTD PMID:20410157 Esr1 Mouse permethrin affects binding ISO Esr1 (Rattus norvegicus) 6480464 Permethrin binds to ESR1 protein CTD PMID:12396874 Esr1 Mouse permethrin increases activity ISO ESR1 (Homo sapiens) 6480464 Permethrin results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse phenanthrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein more ... CTD PMID:12672240 more ... Esr1 Mouse Phenethyl salicylate increases activity ISO ESR1 (Homo sapiens) 6480464 phenethyl salicylate results in increased activity of ESR1 protein CTD PMID:22197706 Esr1 Mouse phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of ESR1 mRNA CTD PMID:23091169 Esr1 Mouse phenobarbital decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Phenobarbital results in decreased expression of ESR1 mRNA CTD PMID:20607812 and PMID:23273579 Esr1 Mouse phenol increases expression ISO ESR1 (Homo sapiens) 6480464 Phenol results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse phenolphthalein increases activity ISO ESR1 (Homo sapiens) 6480464 Phenolphthalein results in increased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse phenolphthalein affects binding ISO ESR1 (Homo sapiens) 6480464 Phenolphthalein binds to ESR1 protein CTD PMID:12598185 Esr1 Mouse phenolphthalein multiple interactions ISO ESR1 (Homo sapiens) 6480464 Phenolphthalein binds to and results in decreased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse phenols multiple interactions ISO ESR1 (Homo sapiens) 6480464 Phenols analog binds to and results in increased activity of ESR1 protein CTD PMID:15952375 Esr1 Mouse phenothrin decreases expression ISO ESR1 (Homo sapiens) 6480464 phenothrin results in decreased expression of ESR1 protein CTD PMID:15118252 Esr1 Mouse phenothrin affects binding ISO ESR1 (Homo sapiens) 6480464 phenothrin binds to ESR1 protein CTD PMID:32278787 Esr1 Mouse phenthoate increases activity ISO ESR1 (Homo sapiens) 6480464 phenthoate results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse phenyl salicylate increases activity ISO ESR1 (Homo sapiens) 6480464 phenyl salicylate results in increased activity of ESR1 protein CTD PMID:22197706 Esr1 Mouse phenyl salicylate multiple interactions ISO ESR1 (Homo sapiens) 6480464 phenyl salicylate binds to and results in increased activity of ESR1 protein CTD PMID:24004914 Esr1 Mouse phenylephrine multiple interactions EXP 6480464 ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine co-treated with Acetylcholine] more ... CTD PMID:17158209 Esr1 Mouse phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of ESR1 mRNA and Phenytoin results in increased expression of ESR1 protein CTD PMID:19490052 Esr1 Mouse PhIP increases activity ISO ESR1 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased activity of ESR1 protein CTD PMID:15319301 Esr1 Mouse PhIP affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine CTD PMID:23208499 Esr1 Mouse PhIP increases expression ISO Esr1 (Rattus norvegicus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:15637090 Esr1 Mouse PhIP multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:15319301 more ... Esr1 Mouse phloretin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Phloretin binds to and results in increased activity of ESR1 protein CTD PMID:9751507 Esr1 Mouse phorbol 13-acetate 12-myristate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA] more ... CTD PMID:20559769 Esr1 Mouse phorbol 13-acetate 12-myristate increases expression ISO ESR1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA CTD PMID:20559769 Esr1 Mouse phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 mRNA more ... CTD PMID:16368122 and PMID:19340542 Esr1 Mouse phorbol 13-acetate 12-myristate decreases expression ISO ESR1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in decreased expression of ESR1 mRNA and Tetradecanoylphorbol Acetate results in decreased expression of ESR1 protein CTD PMID:10633228 and PMID:9706865 Esr1 Mouse phosalone multiple interactions ISO ESR1 (Homo sapiens) 6480464 phosalone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse phoxim multiple interactions ISO ESR1 (Homo sapiens) 6480464 phoxim binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse phoxim affects binding ISO ESR1 (Homo sapiens) 6480464 phoxim binds to ESR1 protein CTD PMID:33872936 Esr1 Mouse phthalic acid affects binding ISO ESR1 (Homo sapiens) 6480464 phthalic acid analog binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse phthalic acid increases degradation ISO ESR1 (Homo sapiens) 6480464 phthalic acid results in increased degradation of ESR1 protein CTD PMID:14702340 Esr1 Mouse phthalic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 phthalic acid analog inhibits the reaction [Estradiol binds to ESR1 protein] more ... CTD PMID:14579009 and PMID:15840436 Esr1 Mouse phytoestrogen decreases expression ISO ESR1 (Homo sapiens) 6480464 Phytoestrogens results in decreased expression of ESR1 mRNA and Phytoestrogens results in decreased expression of ESR1 protein CTD PMID:16033089 Esr1 Mouse phytoestrogen decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Phytoestrogens results in decreased expression of ESR1 mRNA CTD PMID:16731787 Esr1 Mouse phytoestrogen increases expression ISO Esr1 (Rattus norvegicus) 6480464 Phytoestrogens results in increased expression of ESR1 mRNA CTD PMID:16731787 Esr1 Mouse phytoestrogen multiple interactions ISO ESR1 (Homo sapiens) 6480464 Phytoestrogens binds to and results in increased activity of ESR1 protein CTD PMID:16076101 Esr1 Mouse picene affects binding ISO ESR1 (Homo sapiens) 6480464 picene binds to ESR1 protein CTD PMID:32251684 Esr1 Mouse picrotoxinin decreases expression EXP 6480464 picrotoxinin results in decreased expression of ESR1 protein CTD PMID:21278053 Esr1 Mouse piperonyl butoxide decreases expression ISO Esr1 (Rattus norvegicus) 6480464 [Piperonyl Butoxide results in decreased expression of ESR1 mRNA] which results in decreased expression of LIFR mRNA and Piperonyl Butoxide results in decreased expression of ESR1 mRNA CTD PMID:22467018 Esr1 Mouse Pirarubicin increases activity ISO ESR1 (Homo sapiens) 6480464 pirarubicin results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse pirfenidone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein]] which results in decreased susceptibility to Tamoxifen and pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein] CTD PMID:22399296 Esr1 Mouse pirimicarb decreases expression ISO ESR1 (Homo sapiens) 6480464 pirimicarb results in decreased expression of ESR1 mRNA CTD PMID:15261991 Esr1 Mouse pirimiphos-methyl increases activity ISO ESR1 (Homo sapiens) 6480464 pirimiphos methyl results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ESR1 mRNA and [pirinixic acid co-treated with PPARA] results in decreased expression of ESR1 mRNA CTD PMID:19710929 and PMID:20813756 Esr1 Mouse pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of ESR1 mRNA CTD PMID:20813756 and PMID:23811191 Esr1 Mouse platycodin D decreases expression ISO ESR1 (Homo sapiens) 6480464 platycodin D results in decreased expression of ESR1 protein CTD PMID:23867902 Esr1 Mouse potassium atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein promotes the reaction [Estradiol inhibits the reaction [Potassium results in increased secretion of gamma-Aminobutyric Acid]] CTD PMID:19211896 Esr1 Mouse potassium dichromate multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of ESR1 protein CTD PMID:33675932 Esr1 Mouse potassium iodide multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of ESR1 protein and [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein CTD PMID:29050248 Esr1 Mouse prallethrin multiple interactions ISO ESR1 (Homo sapiens) 6480464 d and d-T80-prallethrin binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse pregnenolone multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Pregnenolone results in increased expression of GREB1 mRNA] CTD PMID:33405908 Esr1 Mouse procaine increases expression ISO ESR1 (Homo sapiens) 6480464 Procaine results in increased expression of ESR1 mRNA CTD PMID:22083529 Esr1 Mouse prochloraz decreases expression ISO ESR1 (Homo sapiens) 6480464 prochloraz results in decreased expression of ESR1 mRNA and prochloraz results in decreased expression of ESR1 protein CTD PMID:15130599 Esr1 Mouse prochloraz multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [prochloraz results in decreased expression of ESR1 mRNA] more ... CTD PMID:15130599 more ... Esr1 Mouse prochlorperazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Prochlorperazine binds to and results in increased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse procymidone multiple interactions ISO ESR1 (Homo sapiens) 6480464 procymidone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse progesterone multiple interactions EXP 6480464 ESR1 protein promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IHH mRNA] more ... CTD PMID:17974624 and PMID:25210133 Esr1 Mouse progesterone decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Progesterone results in decreased expression of ESR1 mRNA more ... CTD PMID:16002535 and PMID:19094096 Esr1 Mouse progesterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the reaction [Progesterone results in increased expression of GREB1 mRNA] more ... CTD PMID:22562034 and PMID:33405908 Esr1 Mouse progesterone increases activity ISO ESR1 (Homo sapiens) 6480464 Progesterone results in increased activity of ESR1 protein CTD PMID:22562034 and PMID:25012808 Esr1 Mouse progesterone decreases activity ISO ESR1 (Homo sapiens) 6480464 Progesterone results in decreased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse progesterone multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of ESR1 mRNA more ... CTD PMID:16002535 more ... Esr1 Mouse progesterone decreases expression ISO ESR1 (Homo sapiens) 6480464 Progesterone results in decreased expression of ESR1 mRNA CTD PMID:18037150 Esr1 Mouse propamocarb multiple interactions ISO ESR1 (Homo sapiens) 6480464 [fludioxonil co-treated with N-(2 and 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR1 protein CTD PMID:26812056 Esr1 Mouse propamocarb increases activity ISO ESR1 (Homo sapiens) 6480464 propamocarb results in increased activity of ESR1 protein CTD PMID:26812056 Esr1 Mouse propanil multiple interactions ISO ESR1 (Homo sapiens) 6480464 Propanil binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse propargite multiple interactions ISO ESR1 (Homo sapiens) 6480464 Omite binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse propham increases activity ISO Esr1 (Rattus norvegicus) 6480464 propham results in increased activity of ESR1 protein CTD PMID:33352482 Esr1 Mouse propiconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 propiconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse propoxur multiple interactions ISO ESR1 (Homo sapiens) 6480464 Propoxur inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 Esr1 Mouse propylparaben affects binding ISO Esr1 (Rattus norvegicus) 6480464 propylparaben binds to ESR1 protein CTD PMID:20132880 Esr1 Mouse propylparaben increases expression ISO ESR1 (Homo sapiens) 6480464 propylparaben results in increased expression of ESR1 mRNA and propylparaben results in increased expression of ESR1 protein CTD PMID:25128701 Esr1 Mouse propylparaben affects binding ISO ESR1 (Homo sapiens) 6480464 propylparaben binds to ESR1 protein CTD PMID:11193391 and PMID:19063592 Esr1 Mouse propylparaben increases activity ISO ESR1 (Homo sapiens) 6480464 propylparaben results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse propylparaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [propylparaben results in increased activity of ESR1 protein] and propylparaben binds to and results in increased activity of ESR1 protein CTD PMID:22562034 more ... Esr1 Mouse propyzamide multiple interactions ISO ESR1 (Homo sapiens) 6480464 pronamide binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse prostaglandin E2 increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Dinoprostone results in increased phosphorylation of ESR1 protein CTD PMID:20093341 Esr1 Mouse prostaglandin F2alpha increases expression ISO Esr1 (Rattus norvegicus) 6480464 Dinoprost results in increased expression of ESR1 mRNA CTD PMID:21654155 Esr1 Mouse prothiofos increases activity ISO ESR1 (Homo sapiens) 6480464 prothiophos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse pterostilbene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [resveratrol co-treated with pterostilbene] results in increased expression of ESR1 mRNA and [resveratrol co-treated with pterostilbene] results in increased expression of ESR1 protein CTD PMID:27159275 Esr1 Mouse pterostilbene increases expression ISO ESR1 (Homo sapiens) 6480464 pterostilbene results in increased expression of ESR1 protein CTD PMID:27159275 Esr1 Mouse puerarin decreases expression ISO Esr1 (Rattus norvegicus) 6480464 puerarin results in decreased expression of ESR1 mRNA CTD PMID:22919047 Esr1 Mouse purine-6-thiol increases expression ISO Esr1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of ESR1 mRNA CTD PMID:23358152 Esr1 Mouse pyrazoles multiple interactions ISO ESR1 (Homo sapiens) 6480464 Pyrazoles analog binds to and results in increased activity of ESR1 protein CTD PMID:19772920 Esr1 Mouse pyrene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein more ... CTD PMID:30980910 and PMID:33049310 Esr1 Mouse pyridaben increases activity ISO ESR1 (Homo sapiens) 6480464 pyridaben results in increased activity of ESR1 protein CTD PMID:20143881 Esr1 Mouse pyridaben multiple interactions ISO ESR1 (Homo sapiens) 6480464 pyridaben binds to and results in increased activity of ESR1 protein and pyridaben inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 and PMID:33049310 Esr1 Mouse Pyridate multiple interactions ISO ESR1 (Homo sapiens) 6480464 pyridate inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:15253041 Esr1 Mouse Pyridate affects binding ISO ESR1 (Homo sapiens) 6480464 pyridate binds to ESR1 protein CTD PMID:15253041 Esr1 Mouse pyrimethanil increases activity ISO Esr1 (Rattus norvegicus) 6480464 pyrimethanil results in increased activity of ESR1 protein CTD PMID:33352482 Esr1 Mouse quercetin affects activity ISO ESR1 (Homo sapiens) 6480464 Quercetin affects the activity of ESR1 protein CTD PMID:15185748 Esr1 Mouse quercetin increases expression ISO ESR1 (Homo sapiens) 6480464 Quercetin results in increased expression of ESR1 mRNA CTD PMID:36982678 Esr1 Mouse quercetin affects expression ISO Esr1 (Rattus norvegicus) 6480464 Quercetin affects the expression of ESR1 mRNA CTD PMID:32810592 Esr1 Mouse quercetin affects expression ISO ESR1 (Homo sapiens) 6480464 Quercetin affects the expression of ESR1 mRNA alternative form CTD PMID:32530119 Esr1 Mouse quercetin increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to Quercetin CTD PMID:19194971 Esr1 Mouse quercetin multiple interactions ISO ESR1 (Homo sapiens) 6480464 [bisphenol A co-treated with Quercetin metabolite] results in increased expression of ESR1 mRNA more ... CTD PMID:11502892 more ... Esr1 Mouse quercetin increases expression ISO Esr1 (Rattus norvegicus) 6480464 Quercetin results in increased expression of ESR1 mRNA CTD PMID:23200735 Esr1 Mouse quercetin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Quercetin co-treated with Bucladesine] results in increased expression of ESR1 mRNA more ... CTD PMID:23200735 and PMID:32810592 Esr1 Mouse quercetin increases activity ISO ESR1 (Homo sapiens) 6480464 Quercetin results in increased activity of ESR1 protein CTD PMID:16118406 and PMID:22613215 Esr1 Mouse quercetin affects binding ISO ESR1 (Homo sapiens) 6480464 Quercetin binds to ESR1 protein CTD PMID:14706564 more ... Esr1 Mouse quercetin affects binding ISO Esr1 (Rattus norvegicus) 6480464 Quercetin binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse quercetin decreases expression ISO ESR1 (Homo sapiens) 6480464 Quercetin results in decreased expression of ESR1 mRNA and Quercetin results in decreased expression of ESR1 protein CTD PMID:11502892 and PMID:32530119 Esr1 Mouse quercetin 3-O-beta-D-galactopyranoside multiple interactions ISO ESR1 (Homo sapiens) 6480464 hyperoside inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:22613215 Esr1 Mouse quinaldine multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-methylquinoline analog inhibits the reaction [Estradiol binds to ESR1 protein] and 2-methylquinoline inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:30896932 Esr1 Mouse quinaldine increases activity ISO ESR1 (Homo sapiens) 6480464 2-methylquinoline analog results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse quinalphos increases activity ISO ESR1 (Homo sapiens) 6480464 quinalphos results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse quinizarin multiple interactions ISO ESR1 (Homo sapiens) 6480464 1 and 4-dihydroxyanthraquinone binds to and results in increased activity of ESR1 protein CTD PMID:20707409 Esr1 Mouse quinolin-4-ol increases activity ISO ESR1 (Homo sapiens) 6480464 4-hydroxyquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse quinolin-4-ol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxyquinoline inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:30896932 Esr1 Mouse quinolin-6-ol multiple interactions ISO ESR1 (Homo sapiens) 6480464 6-hydroxyquinoline inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:30896932 Esr1 Mouse quinolin-6-ol increases activity ISO ESR1 (Homo sapiens) 6480464 6-hydroxyquinoline results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse quinoline multiple interactions ISO ESR1 (Homo sapiens) 6480464 quinoline inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:30896932 Esr1 Mouse quinoline increases activity ISO ESR1 (Homo sapiens) 6480464 quinoline analog results in increased activity of ESR1 protein CTD PMID:30896932 Esr1 Mouse quinoline yellow decreases expression ISO ESR1 (Homo sapiens) 6480464 quinoline yellow results in decreased expression of ESR1 protein CTD PMID:31957441 Esr1 Mouse ractopamine multiple interactions ISO ESR1 (Homo sapiens) 6480464 ractopamine binds to and results in increased activity of ESR1 protein CTD PMID:24928891 Esr1 Mouse radicicol decreases expression ISO ESR1 (Homo sapiens) 6480464 monorden analog results in decreased expression of ESR1 protein and monorden results in decreased expression of ESR1 protein CTD PMID:11448926 Esr1 Mouse raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of ESR1 mRNA and Raloxifene Hydrochloride results in increased expression of ESR1 protein CTD PMID:25571714 Esr1 Mouse raloxifene decreases expression EXP 6480464 Raloxifene Hydrochloride results in decreased expression of ESR1 protein CTD PMID:26879975 Esr1 Mouse raloxifene multiple interactions EXP 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of ESR1 protein more ... CTD PMID:24846829 more ... Esr1 Mouse raloxifene affects expression ISO Esr1 (Rattus norvegicus) 6480464 Raloxifene Hydrochloride affects the expression of ESR1 mRNA CTD PMID:19350480 Esr1 Mouse raloxifene affects binding ISO Esr1 (Rattus norvegicus) 6480464 Raloxifene Hydrochloride metabolite binds to ESR1 protein CTD PMID:16790557 Esr1 Mouse raloxifene affects folding ISO ESR1 (Homo sapiens) 6480464 Raloxifene Hydrochloride affects the folding of ESR1 protein CTD PMID:16497877 Esr1 Mouse raloxifene increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 exon polymorphism results in increased susceptibility to Raloxifene Hydrochloride CTD PMID:17350824 Esr1 Mouse raloxifene affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 gene polymorphism affects the susceptibility to Raloxifene Hydrochloride CTD PMID:15807179 and PMID:16604479 Esr1 Mouse raloxifene decreases expression ISO ESR1 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased expression of ESR1 mRNA and Raloxifene Hydrochloride results in decreased expression of ESR1 protein CTD PMID:11535548 more ... Esr1 Mouse raloxifene decreases activity ISO ESR1 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased activity of ESR1 protein CTD PMID:17654759 and PMID:21543282 Esr1 Mouse raloxifene affects binding EXP 6480464 Raloxifene Hydrochloride binds to ESR1 protein CTD PMID:15161930 Esr1 Mouse raloxifene increases expression ISO ESR1 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in increased expression of ESR1 mRNA and Raloxifene Hydrochloride results in increased expression of ESR1 protein CTD PMID:19432593 more ... Esr1 Mouse raloxifene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein] more ... CTD PMID:14699072 more ... Esr1 Mouse raloxifene multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA] and ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA] CTD PMID:24782323 Esr1 Mouse raloxifene affects binding ISO ESR1 (Homo sapiens) 6480464 [Raloxifene Hydrochloride binds to ESR1 protein] which binds to SERPINB9 protein more ... CTD PMID:14617632 more ... Esr1 Mouse resmethrin affects binding ISO ESR1 (Homo sapiens) 6480464 resmethrin binds to ESR1 protein CTD PMID:32278787 Esr1 Mouse resorcinol affects binding ISO ESR1 (Homo sapiens) 6480464 resorcinol binds to ESR1 protein CTD PMID:12598185 Esr1 Mouse resveratrol multiple interactions ISO ESR1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of ESR1 protein] more ... CTD PMID:11014220 more ... Esr1 Mouse resveratrol increases expression ISO ESR1 (Homo sapiens) 6480464 resveratrol results in increased expression of ESR1 mRNA CTD PMID:15149879 and PMID:27159275 Esr1 Mouse resveratrol decreases expression ISO ESR1 (Homo sapiens) 6480464 resveratrol analog results in decreased expression of ESR1 mRNA more ... CTD PMID:11507064 more ... Esr1 Mouse resveratrol affects binding ISO ESR1 (Homo sapiens) 6480464 resveratrol binds to ESR1 protein CTD PMID:11014220 more ... Esr1 Mouse resveratrol increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 resveratrol results in increased phosphorylation of ESR1 protein CTD PMID:15615701 and PMID:18296501 Esr1 Mouse resveratrol decreases expression ISO Esr1 (Rattus norvegicus) 6480464 resveratrol results in decreased expression of ESR1 mRNA and resveratrol results in decreased expression of ESR1 protein CTD PMID:11218048 and PMID:22104698 Esr1 Mouse resveratrol increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein results in increased susceptibility to resveratrol CTD PMID:14750165 Esr1 Mouse resveratrol multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [4 more ... CTD PMID:18426865 more ... Esr1 Mouse resveratrol increases degradation ISO ESR1 (Homo sapiens) 6480464 resveratrol results in increased degradation of ESR1 protein CTD PMID:14750165 Esr1 Mouse resveratrol affects binding ISO Esr1 (Rattus norvegicus) 6480464 resveratrol analog binds to ESR1 protein and resveratrol binds to ESR1 protein CTD PMID:27420082 Esr1 Mouse resveratrol increases response to substance EXP 6480464 ESR1 protein results in increased susceptibility to resveratrol CTD PMID:17872969 Esr1 Mouse resveratrol increases activity ISO ESR1 (Homo sapiens) 6480464 resveratrol results in increased activity of ESR1 protein and resveratrol results in increased activity of ESR1 protein mutant form CTD PMID:10854714 more ... Esr1 Mouse resveratrol affects localization ISO ESR1 (Homo sapiens) 6480464 resveratrol affects the localization of ESR1 protein CTD PMID:17513867 Esr1 Mouse resveratrol affects response to substance ISO Esr1 (Rattus norvegicus) 6480464 ESR1 protein affects the susceptibility to resveratrol CTD PMID:19400946 Esr1 Mouse rhapontigenin increases activity ISO ESR1 (Homo sapiens) 6480464 rhapontigenin analog results in increased activity of ESR1 protein CTD PMID:17935960 Esr1 Mouse ritonavir decreases expression ISO ESR1 (Homo sapiens) 6480464 Ritonavir results in decreased expression of ESR1 protein CTD PMID:16551874 Esr1 Mouse rosuvastatin calcium decreases expression EXP 6480464 Rosuvastatin Calcium results in decreased expression of ESR1 protein CTD PMID:32771489 Esr1 Mouse rotenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Rotenone binds to and results in decreased activity of ESR1 protein and Rotenone inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:25752796 and PMID:30818834 Esr1 Mouse rotenone decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of ESR1 mRNA CTD PMID:28374803 Esr1 Mouse royal jelly increases activity ISO ESR1 (Homo sapiens) 6480464 royal jelly results in increased activity of ESR1 protein CTD PMID:15946813 Esr1 Mouse royal jelly affects binding ISO ESR1 (Homo sapiens) 6480464 royal jelly binds to ESR1 protein CTD PMID:17287592 Esr1 Mouse royal jelly multiple interactions ISO ESR1 (Homo sapiens) 6480464 Estradiol inhibits the reaction [royal jelly binds to ESR1 protein] more ... CTD PMID:15946813 and PMID:17287592 Esr1 Mouse RU 58668 multiple interactions ISO ESR1 (Homo sapiens) 6480464 RU 58668 inhibits the reaction [Estradiol results in increased activity of ESR1 protein] more ... CTD PMID:15868441 and PMID:20599613 Esr1 Mouse rubitecan multiple interactions ISO ESR1 (Homo sapiens) 6480464 rubitecan binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse S-adenosyl-L-methioninate multiple interactions ISO ESR1 (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA] more ... CTD PMID:22558281 Esr1 Mouse S-adenosyl-L-methionine multiple interactions ISO ESR1 (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA] more ... CTD PMID:22558281 Esr1 Mouse salicylates multiple interactions ISO ESR1 (Homo sapiens) 6480464 Salicylates analog binds to and results in increased activity of ESR1 protein CTD PMID:12628652 Esr1 Mouse SB 203580 multiple interactions ISO ESR1 (Homo sapiens) 6480464 [SB 203580 co-treated with naringenin] results in increased degradation of ESR1 protein more ... CTD PMID:19194971 and PMID:24586459 Esr1 Mouse SB 203580 decreases expression EXP 6480464 SB 203580 results in decreased expression of ESR1 protein CTD PMID:19340542 Esr1 Mouse SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Estradiol results in increased expression of ESR1 protein] CTD PMID:19340542 Esr1 Mouse Se-methyl-L-selenocysteine decreases expression ISO ESR1 (Homo sapiens) 6480464 selenomethylselenocysteine results in decreased expression of ESR1 protein CTD PMID:18855134 Esr1 Mouse Se-methyl-L-selenocysteine multiple interactions ISO ESR1 (Homo sapiens) 6480464 [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein CTD PMID:18855134 Esr1 Mouse Se-methylselenocysteine decreases expression ISO ESR1 (Homo sapiens) 6480464 selenomethylselenocysteine results in decreased expression of ESR1 protein CTD PMID:18855134 Esr1 Mouse Se-methylselenocysteine multiple interactions ISO ESR1 (Homo sapiens) 6480464 [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein CTD PMID:18855134 Esr1 Mouse Selamectin increases expression EXP 6480464 selamectin results in increased expression of ESR1 CTD PMID:26078298 Esr1 Mouse Selamectin increases expression ISO ESR1 (Homo sapiens) 6480464 selamectin results in increased expression of ESR1 CTD PMID:26078298 Esr1 Mouse selenium atom multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA] CTD PMID:30526071 Esr1 Mouse semicarbazide multiple interactions ISO ESR1 (Homo sapiens) 6480464 carbamylhydrazine inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:19788891 Esr1 Mouse silibinin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Silybin results in increased activity of [ESR1 protein binds to ESR2 protein] CTD PMID:16076518 Esr1 Mouse silibinin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Silybin results in increased activity of [ESR1 protein binds to ESR2 protein] CTD PMID:16076518 Esr1 Mouse simazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Simazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein] CTD PMID:8858116 Esr1 Mouse simazine affects binding ISO ESR1 (Homo sapiens) 6480464 Simazine binds to ESR1 protein CTD PMID:8858116 Esr1 Mouse sirolimus increases expression ISO ESR1 (Homo sapiens) 6480464 Sirolimus results in increased expression of ESR1 protein CTD PMID:19016759 Esr1 Mouse sirolimus increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Sirolimus results in increased phosphorylation of ESR1 protein CTD PMID:19016759 Esr1 Mouse sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of ESR1 protein CTD PMID:10873715 Esr1 Mouse sodium arsenite multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of ESR1 mRNA more ... CTD PMID:23192986 more ... Esr1 Mouse sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ESR1 mRNA CTD PMID:37682722 and PMID:38266874 Esr1 Mouse sodium arsenite affects methylation ISO ESR1 (Homo sapiens) 6480464 sodium arsenite affects the methylation of ESR1 gene CTD PMID:28589171 Esr1 Mouse sodium arsenite multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 4 more ... CTD PMID:21964460 more ... Esr1 Mouse sodium arsenite decreases expression ISO Esr1 (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of ESR1 mRNA and sodium arsenite results in decreased expression of ESR1 protein CTD PMID:20598115 more ... Esr1 Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ESR1 mRNA and sodium arsenite results in increased expression of ESR1 protein CTD PMID:14691202 more ... Esr1 Mouse sodium arsenite multiple interactions EXP 6480464 [Diethylstilbestrol co-treated with sodium arsenite] results in increased expression of ESR1 protein more ... CTD PMID:16368122 more ... Esr1 Mouse sodium arsenite increases expression ISO ESR1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ESR1 mRNA CTD PMID:21776218 more ... Esr1 Mouse sodium arsenite decreases expression ISO ESR1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ESR1 mRNA and sodium arsenite results in decreased expression of ESR1 protein CTD PMID:17283378 more ... Esr1 Mouse sodium benzoate decreases activity ISO ESR1 (Homo sapiens) 6480464 Sodium Benzoate results in decreased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse sodium fluoride increases expression ISO Esr1 (Rattus norvegicus) 6480464 Sodium Fluoride results in increased expression of ESR1 mRNA and Sodium Fluoride results in increased expression of ESR1 protein CTD PMID:24071475 and PMID:29323457 Esr1 Mouse sodium fluoride multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Sodium Fluoride inhibits the reaction [Triclosan results in increased expression of ESR1 mRNA] and Sodium Fluoride inhibits the reaction [Triclosan results in increased expression of ESR1 protein] CTD PMID:29323457 Esr1 Mouse sophoraflavanone B multiple interactions ISO ESR1 (Homo sapiens) 6480464 8-prenylnaringenin analog binds to and results in increased activity of ESR1 protein more ... CTD PMID:12650720 more ... Esr1 Mouse sophoraflavanone B increases expression ISO Esr1 (Rattus norvegicus) 6480464 8-prenylnaringenin results in increased expression of ESR1 mRNA CTD PMID:34848279 Esr1 Mouse sophoraflavanone B decreases expression ISO Esr1 (Rattus norvegicus) 6480464 8-prenylnaringenin results in decreased expression of ESR1 protein CTD PMID:34848279 Esr1 Mouse sophoraflavanone B multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Fulvestrant co-treated with 8-prenylnaringenin] results in increased expression of ESR1 mRNA and Fulvestrant inhibits the reaction [8-prenylnaringenin results in decreased expression of ESR1 protein] CTD PMID:34848279 Esr1 Mouse sophoraflavanone B decreases expression ISO ESR1 (Homo sapiens) 6480464 8-prenylnaringenin results in decreased expression of ESR1 protein CTD PMID:32986415 Esr1 Mouse sophoraflavanone B increases activity ISO ESR1 (Homo sapiens) 6480464 8-prenylnaringenin results in increased activity of ESR1 protein CTD PMID:12623674 and PMID:17716812 Esr1 Mouse Sophoricoside decreases expression EXP 6480464 sophoricoside results in decreased expression of ESR1 CTD PMID:24877640 Esr1 Mouse staurosporine multiple interactions ISO ESR1 (Homo sapiens) 6480464 Staurosporine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse stigmasterol multiple interactions EXP 6480464 [bisphenol A co-treated with Stigmasterol] results in increased expression of ESR1 mRNA and NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of ESR1 mRNA] CTD PMID:30245210 Esr1 Mouse stilben-4-ol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxystilbene analog binds to and results in increased activity of ESR1 protein and fulvestrant inhibits the reaction [4-hydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 Esr1 Mouse stilbene-4,4'-diol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4 more ... CTD PMID:19496085 Esr1 Mouse streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of ESR1 mRNA CTD PMID:24781736 Esr1 Mouse streptozocin increases expression ISO Esr1 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of ESR1 CTD PMID:32469605 Esr1 Mouse streptozocin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein CTD PMID:30421503 Esr1 Mouse streptozocin multiple interactions EXP 6480464 bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA] more ... CTD PMID:24781736 Esr1 Mouse styrenes affects binding ISO ESR1 (Homo sapiens) 6480464 Styrenes analog binds to ESR1 protein CTD PMID:11485868 Esr1 Mouse succimer multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Succimer inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ESR1 protein] and Succimer inhibits the reaction [sodium arsenite results in decreased expression of ESR1 protein] CTD PMID:31163222 and PMID:32402895 Esr1 Mouse sulforaphane multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 mutant form promotes the reaction [3 and 3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]] CTD PMID:23583297 Esr1 Mouse sulindac sulfide decreases expression ISO ESR1 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of ESR1 mRNA and sulindac sulfide results in decreased expression of ESR1 protein CTD PMID:16740773 Esr1 Mouse sulindac sulfone decreases expression ISO ESR1 (Homo sapiens) 6480464 sulindac sulfone results in decreased expression of ESR1 mRNA and sulindac sulfone results in decreased expression of ESR1 protein CTD PMID:16740773 Esr1 Mouse sunitinib increases expression ISO ESR1 (Homo sapiens) 6480464 Sunitinib results in increased expression of ESR1 mRNA CTD PMID:31533062 Esr1 Mouse Sunset Yellow FCF multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt results in increased activity of ESR1 protein] CTD PMID:22562034 Esr1 Mouse Sunset Yellow FCF increases activity ISO ESR1 (Homo sapiens) 6480464 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse superoxide multiple interactions ISO ESR1 (Homo sapiens) 6480464 [4 more ... CTD PMID:18354059 and PMID:23000059 Esr1 Mouse Swertiamarin multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 swertiamarin inhibits the reaction [Testosterone results in increased expression of ESR1 protein] CTD PMID:27866977 Esr1 Mouse tamibarotene increases activity ISO ESR1 (Homo sapiens) 6480464 tamibarotene results in increased activity of ESR1 protein CTD PMID:25257666 Esr1 Mouse tamoxifen multiple interactions ISO ESR1 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [[Tamoxifen co-treated with N-desmethyltamoxifen co-treated with afimoxifene] results in increased stability of ESR1 protein] more ... CTD PMID:11174852 more ... Esr1 Mouse tamoxifen increases activity ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in increased activity of ESR1 protein CTD PMID:15103026 more ... Esr1 Mouse tamoxifen affects response to substance EXP 6480464 ESR1 protein affects the susceptibility to Tamoxifen CTD PMID:22841776 Esr1 Mouse tamoxifen affects binding EXP 6480464 Tamoxifen binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse tamoxifen decreases activity ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in decreased activity of ESR1 protein CTD PMID:20208560 and PMID:21543282 Esr1 Mouse tamoxifen affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 mRNA alternative form affects the susceptibility to Tamoxifen and ESR1 protein affects the susceptibility to Tamoxifen CTD PMID:19011961 more ... Esr1 Mouse tamoxifen increases expression ISO Esr1 (Rattus norvegicus) 6480464 Tamoxifen results in increased expression of ESR1 protein CTD PMID:11748029 Esr1 Mouse tamoxifen affects binding ISO Esr1 (Rattus norvegicus) 6480464 Tamoxifen binds to ESR1 protein and Tamoxifen metabolite binds to ESR1 protein CTD PMID:16790557 and PMID:19913605 Esr1 Mouse tamoxifen multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Tamoxifen inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to NCOA1 protein]] CTD PMID:19460436 Esr1 Mouse tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of ESR1 mRNA CTD PMID:15236189 Esr1 Mouse tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of ESR1 mRNA CTD PMID:17555576 Esr1 Mouse tamoxifen multiple interactions EXP 6480464 [arsenic trioxide co-treated with Tamoxifen] results in decreased methylation of ESR1 gene more ... CTD PMID:15750629 more ... Esr1 Mouse tamoxifen increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in increased phosphorylation of ESR1 protein CTD PMID:20103631 Esr1 Mouse tamoxifen increases stability ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in increased stability of ESR1 protein CTD PMID:19477949 Esr1 Mouse tamoxifen increases expression ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in increased expression of ESR1 mRNA and Tamoxifen results in increased expression of ESR1 protein CTD PMID:12627041 more ... Esr1 Mouse tamoxifen decreases expression ISO ESR1 (Homo sapiens) 6480464 Tamoxifen results in decreased expression of ESR1 mRNA more ... CTD PMID:20549698 more ... Esr1 Mouse tamoxifen affects binding ISO ESR1 (Homo sapiens) 6480464 Tamoxifen binds to ESR1 protein and Tamoxifen metabolite binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse tamoxifen affects methylation ISO ESR1 (Homo sapiens) 6480464 Tamoxifen affects the methylation of ESR1 promoter CTD PMID:20473856 Esr1 Mouse tamoxifen affects expression ISO ESR1 (Homo sapiens) 6480464 Tamoxifen affects the expression of ESR1 mRNA CTD PMID:20543978 Esr1 Mouse tamoxifen affects activity ISO ESR1 (Homo sapiens) 6480464 Tamoxifen affects the activity of ESR1 protein CTD PMID:19339991 Esr1 Mouse tamoxifen decreases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 gene polymorphism results in decreased susceptibility to Tamoxifen and ESR1 protein results in decreased susceptibility to Tamoxifen CTD PMID:19487384 and PMID:20556506 Esr1 Mouse tamoxifen increases response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein alternative form results in increased susceptibility to Tamoxifen and ESR1 protein results in increased susceptibility to Tamoxifen CTD PMID:20208560 and PMID:20302909 Esr1 Mouse tartrazine increases activity ISO ESR1 (Homo sapiens) 6480464 Tartrazine results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse tartrazine multiple interactions ISO ESR1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Tartrazine results in increased activity of ESR1 protein] CTD PMID:22562034 Esr1 Mouse tea tree oil increases activity ISO ESR1 (Homo sapiens) 6480464 Tea Tree Oil results in increased activity of ESR1 protein CTD PMID:31393563 Esr1 Mouse tebuconazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 tebuconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse tegaserod multiple interactions ISO ESR1 (Homo sapiens) 6480464 tegaserod binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse Temsirolimus decreases activity ISO ESR1 (Homo sapiens) 6480464 temsirolimus results in decreased activity of ESR1 protein CTD PMID:16954435 Esr1 Mouse teniposide multiple interactions ISO ESR1 (Homo sapiens) 6480464 Teniposide binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse terbufos affects binding ISO ESR1 (Homo sapiens) 6480464 terbufos binds to ESR1 protein CTD PMID:33872936 Esr1 Mouse terbutylazine increases activity ISO ESR1 (Homo sapiens) 6480464 terbutylazine results in increased activity of ESR1 protein CTD PMID:28728110 Esr1 Mouse testosterone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [ESR1 protein binds to TRAF6 protein] more ... CTD PMID:12676605 more ... Esr1 Mouse testosterone decreases expression ISO ESR1 (Homo sapiens) 6480464 Testosterone results in decreased expression of ESR1 mRNA CTD PMID:33728745 Esr1 Mouse testosterone increases expression EXP 6480464 Testosterone results in increased expression of ESR1 mRNA alternative form CTD PMID:12399412 Esr1 Mouse testosterone increases expression ISO Esr1 (Rattus norvegicus) 6480464 Testosterone results in increased expression of ESR1 mRNA and Testosterone results in increased expression of ESR1 protein CTD PMID:15917159 more ... Esr1 Mouse testosterone multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Finasteride inhibits the reaction [Testosterone results in increased expression of ESR1 protein] more ... CTD PMID:23500659 more ... Esr1 Mouse testosterone decreases abundance EXP 6480464 ESR1 protein results in decreased abundance of Testosterone CTD PMID:20833731 Esr1 Mouse testosterone increases activity ISO ESR1 (Homo sapiens) 6480464 Testosterone results in increased activity of ESR1 protein CTD PMID:22562034 Esr1 Mouse testosterone affects binding ISO ESR1 (Homo sapiens) 6480464 Testosterone binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse testosterone decreases expression EXP 6480464 Testosterone results in decreased expression of ESR1 mRNA and Testosterone results in decreased expression of ESR1 protein CTD PMID:15916834 more ... Esr1 Mouse testosterone enanthate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 testosterone enanthate results in decreased expression of ESR1 mRNA CTD PMID:21427060 Esr1 Mouse testosterone enanthate increases activity ISO Esr1 (Rattus norvegicus) 6480464 testosterone enanthate results in increased activity of ESR1 protein CTD PMID:12504345 Esr1 Mouse testosterone enanthate increases expression ISO Esr1 (Rattus norvegicus) 6480464 testosterone enanthate results in increased expression of ESR1 mRNA and testosterone enanthate results in increased expression of ESR1 protein CTD PMID:21729141 Esr1 Mouse Testosterone propionate decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Testosterone Propionate results in decreased expression of ESR1 protein CTD PMID:23669243 Esr1 Mouse Testosterone propionate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Testosterone Propionate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse Tetrachlorobisphenol A affects binding ISO ESR1 (Homo sapiens) 6480464 tetrachlorodian binds to ESR1 protein CTD PMID:12753421 Esr1 Mouse Tetrachlorobisphenol A affects expression ISO ESR1 (Homo sapiens) 6480464 tetrachlorodian affects the expression of ESR1 mRNA CTD PMID:33582643 Esr1 Mouse Tetrachlorobisphenol A increases expression ISO ESR1 (Homo sapiens) 6480464 tetrachlorodian results in increased expression of ESR1 protein CTD PMID:33582643 Esr1 Mouse Tetrachlorobisphenol A multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [tetrachlorodian results in increased expression of ESR1 mRNA] CTD PMID:37992829 Esr1 Mouse Tetrachlorobisphenol A increases expression EXP 6480464 tetrachlorodian results in increased expression of ESR1 mRNA and tetrachlorodian results in increased expression of ESR1 protein CTD PMID:37992829 Esr1 Mouse Tetrachlorobisphenol A affects expression ISO Esr1 (Rattus norvegicus) 6480464 tetrachlorodian affects the expression of ESR1 mRNA CTD PMID:37992829 Esr1 Mouse Tetrachlorobisphenol A increases activity ISO ESR1 (Homo sapiens) 6480464 tetrachlorodian results in increased activity of ESR1 protein CTD PMID:21561829 and PMID:31388671 Esr1 Mouse Tetrachlorobisphenol A multiple interactions ISO ESR1 (Homo sapiens) 6480464 tetrachlorodian binds to and results in increased activity of ESR1 protein and tetrachlorodian inhibits the reaction [Coumestrol binds to ESR1 protein modified form] CTD PMID:21622942 more ... Esr1 Mouse tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ESR1 mRNA CTD PMID:17484886 and PMID:31919559 Esr1 Mouse tetrachloromethane decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of ESR1 mRNA CTD PMID:31150632 Esr1 Mouse tetrachloromethane increases expression ISO Esr1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of ESR1 mRNA CTD PMID:14716833 Esr1 Mouse tetrachlorvinphos multiple interactions ISO ESR1 (Homo sapiens) 6480464 Tetrachlorvinphos binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse tetradifon increases activity ISO ESR1 (Homo sapiens) 6480464 tetradifon results in increased activity of ESR1 protein CTD PMID:26139245 Esr1 Mouse tetrahydropalmatine decreases expression EXP 6480464 tetrahydropalmatine results in decreased expression of ESR1 mRNA CTD PMID:37606869 Esr1 Mouse tetrahydropalmatine multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 tetrahydropalmatine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA] CTD PMID:37606869 Esr1 Mouse tetralin decreases activity ISO ESR1 (Homo sapiens) 6480464 tetralin analog results in decreased activity of ESR1 protein CTD PMID:15737489 Esr1 Mouse tetralin increases activity ISO ESR1 (Homo sapiens) 6480464 tetralin analog results in increased activity of ESR1 protein CTD PMID:15737489 Esr1 Mouse tetramethrin decreases expression ISO Esr1 (Rattus norvegicus) 6480464 tetramethrin results in decreased expression of ESR1 protein CTD PMID:16326440 Esr1 Mouse tetraphene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with chrysene] results in increased expression of ESR1 mRNA more ... CTD PMID:11922773 and PMID:12441364 Esr1 Mouse tetraphene decreases expression ISO Esr1 (Rattus norvegicus) 6480464 benz(a)anthracene results in decreased expression of ESR1 protein CTD PMID:18634860 and PMID:21783948 Esr1 Mouse tetraphene increases activity ISO ESR1 (Homo sapiens) 6480464 benz(a)anthracene results in increased activity of ESR1 protein CTD PMID:25012808 Esr1 Mouse tetraphene increases phosphorylation ISO ESR1 (Homo sapiens) 6480464 benz(a)anthracene results in increased phosphorylation of ESR1 protein CTD PMID:12441364 Esr1 Mouse tetraphene increases expression ISO ESR1 (Homo sapiens) 6480464 benz(a)anthracene results in increased expression of ESR1 mRNA CTD PMID:11922773 Esr1 Mouse thiamethoxam decreases expression EXP 6480464 Thiamethoxam results in decreased expression of ESR1 protein CTD PMID:33533595 Esr1 Mouse thiamethoxam affects binding ISO ESR1 (Homo sapiens) 6480464 Thiamethoxam binds to ESR1 protein CTD PMID:31550567 Esr1 Mouse thioacetamide decreases expression ISO Esr1 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of ESR1 mRNA CTD PMID:23411599 Esr1 Mouse tibolone increases activity ISO ESR1 (Homo sapiens) 6480464 tibolone metabolite results in increased activity of ESR1 protein and tibolone results in increased activity of ESR1 protein CTD PMID:16720731 Esr1 Mouse tin(II) chloride (anhydrous) multiple interactions ISO ESR1 (Homo sapiens) 6480464 stannous chloride inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12746304 Esr1 Mouse tin(II) chloride (anhydrous) increases activity ISO ESR1 (Homo sapiens) 6480464 stannous chloride results in increased activity of ESR1 protein CTD PMID:12746304 Esr1 Mouse tin(II) chloride (anhydrous) affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to stannous chloride CTD PMID:12746304 Esr1 Mouse tin(II) chloride (anhydrous) decreases expression ISO ESR1 (Homo sapiens) 6480464 stannous chloride results in decreased expression of ESR1 mRNA and stannous chloride results in decreased expression of ESR1 protein CTD PMID:12746304 Esr1 Mouse tiratricol multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:33049310 Esr1 Mouse titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of ESR1 mRNA CTD PMID:23557971 and PMID:29264374 Esr1 Mouse titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of ESR1 mRNA CTD PMID:35295148 Esr1 Mouse titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ESR1 mRNA CTD PMID:29950665 Esr1 Mouse tolclofos-methyl increases activity ISO ESR1 (Homo sapiens) 6480464 tolclofos-methyl results in increased activity of ESR1 protein CTD PMID:15064155 Esr1 Mouse tolclofos-methyl affects binding ISO ESR1 (Homo sapiens) 6480464 tolclofos-methyl binds to ESR1 protein CTD PMID:33872936 Esr1 Mouse topotecan multiple interactions ISO ESR1 (Homo sapiens) 6480464 Topotecan inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse toremifene multiple interactions EXP 6480464 Toremifene inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA] and Toremifene inhibits the reaction [Estradiol results in increased expression of ESR1 protein] CTD PMID:12079510 Esr1 Mouse toremifene multiple interactions ISO ESR1 (Homo sapiens) 6480464 Toremifene binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse toxaphene increases expression ISO ESR1 (Homo sapiens) 6480464 Toxaphene results in increased expression of ESR1 mRNA CTD PMID:21295777 Esr1 Mouse toxaphene increases activity ISO ESR1 (Homo sapiens) 6480464 Toxaphene results in increased activity of ESR1 protein CTD PMID:26022396 Esr1 Mouse toxaphene increases activity ISO Esr1 (Rattus norvegicus) 6480464 Toxaphene results in increased activity of ESR1 protein CTD PMID:9860891 Esr1 Mouse toxaphene affects binding ISO ESR1 (Homo sapiens) 6480464 Toxaphene binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse toxaphene multiple interactions ISO ESR1 (Homo sapiens) 6480464 [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA more ... CTD PMID:10774817 more ... Esr1 Mouse TRAM-34 decreases expression ISO ESR1 (Homo sapiens) 6480464 TRAM 34 results in decreased expression of ESR1 mRNA CTD PMID:20050851 Esr1 Mouse trans-anethole affects binding ISO ESR1 (Homo sapiens) 6480464 anethole metabolite binds to ESR1 protein CTD PMID:12818366 Esr1 Mouse trans-anethole affects binding ISO Esr1 (Rattus norvegicus) 6480464 anethole analog binds to ESR1 protein CTD PMID:27420082 Esr1 Mouse trans-anethole multiple interactions ISO ESR1 (Homo sapiens) 6480464 anethole metabolite inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:12818366 Esr1 Mouse trans-stilbene-4,4'-diol multiple interactions ISO ESR1 (Homo sapiens) 6480464 4 more ... CTD PMID:19496085 Esr1 Mouse trenbolone multiple interactions ISO ESR1 (Homo sapiens) 6480464 Trenbolone Acetate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse Tri-2-ethylhexyl trimellitate increases activity ISO ESR1 (Homo sapiens) 6480464 tri-(2-ethylhexyl)trimellitate metabolite results in increased activity of ESR1 protein and tri-(2-ethylhexyl)trimellitate results in increased activity of ESR1 protein CTD PMID:16756374 and PMID:35089383 Esr1 Mouse Tri-2-ethylhexyl trimellitate multiple interactions ISO ESR1 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [tri-(2-ethylhexyl)trimellitate metabolite results in increased activity of ESR1 protein] more ... CTD PMID:16756374 more ... Esr1 Mouse triadimefon multiple interactions ISO ESR1 (Homo sapiens) 6480464 triadimefon binds to and results in increased activity of ESR1 protein CTD PMID:10789375 Esr1 Mouse triadimefon increases expression EXP 6480464 triadimefon results in increased expression of ESR1 mRNA CTD PMID:19363144 Esr1 Mouse tributyl phosphate multiple interactions ISO ESR1 (Homo sapiens) 6480464 tributyl phosphate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse tributylstannane increases expression ISO ESR1 (Homo sapiens) 6480464 tributyltin results in increased expression of ESR1 mRNA CTD PMID:23523586 Esr1 Mouse tributylstannane decreases expression ISO Esr1 (Rattus norvegicus) 6480464 tributyltin results in decreased expression of ESR1 protein CTD PMID:27521499 more ... Esr1 Mouse tributylstannane affects expression ISO Esr1 (Rattus norvegicus) 6480464 tributyltin affects the expression of ESR1 protein CTD PMID:25819109 Esr1 Mouse tributylstannane multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 fulvestrant inhibits the reaction [tributyltin affects the expression of ESR1 protein] CTD PMID:25819109 Esr1 Mouse tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of ESR1 protein CTD PMID:25819109 more ... Esr1 Mouse tributylstannane multiple interactions EXP 6480464 Estrogens inhibits the reaction [tributyltin results in decreased expression of ESR1 protein] more ... CTD PMID:25819109 Esr1 Mouse tributylstannane multiple interactions ISO ESR1 (Homo sapiens) 6480464 tributyltin binds to and results in increased activity of ESR1 protein and tributyltin results in increased expression of and affects the localization of ESR1 protein CTD PMID:23523586 Esr1 Mouse trichloroethene increases expression ISO Esr1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of ESR1 mRNA CTD PMID:33387578 Esr1 Mouse trichostatin A multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Decitabine co-treated with trichostatin A] affects the expression of ESR1 mRNA more ... CTD PMID:17533736 more ... Esr1 Mouse trichostatin A multiple interactions EXP 6480464 [estradiol dipropionate co-treated with trichostatin A] results in decreased expression of ESR1 protein CTD PMID:15930180 Esr1 Mouse trichostatin A increases expression ISO ESR1 (Homo sapiens) 6480464 trichostatin A results in increased expression of ESR1 mRNA CTD PMID:18092350 Esr1 Mouse trichostatin A decreases stability ISO ESR1 (Homo sapiens) 6480464 trichostatin A results in decreased stability of ESR1 mRNA CTD PMID:17891453 Esr1 Mouse trichostatin A decreases expression ISO ESR1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of ESR1 mRNA and trichostatin A results in decreased expression of ESR1 protein CTD PMID:17891453 and PMID:22476901 Esr1 Mouse triclocarban multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 mutant form inhibits the reaction [[Estradiol co-treated with triclocarban] results in increased expression of CYP1A1 mRNA] more ... CTD PMID:18795164 more ... Esr1 Mouse triclocarban decreases expression ISO ESR1 (Homo sapiens) 6480464 triclocarban results in decreased expression of ESR1 mRNA and triclocarban results in decreased expression of ESR1 protein CTD PMID:24740835 Esr1 Mouse triclosan multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 mutant form inhibits the reaction [Triclosan results in increased expression of CCND1 mRNA] more ... CTD PMID:17992702 more ... Esr1 Mouse triclosan increases expression ISO Esr1 (Rattus norvegicus) 6480464 Triclosan results in increased expression of ESR1 mRNA and Triclosan results in increased expression of ESR1 protein CTD PMID:29323457 Esr1 Mouse triclosan decreases expression ISO ESR1 (Homo sapiens) 6480464 Triclosan results in decreased expression of ESR1 mRNA and Triclosan results in decreased expression of ESR1 protein CTD PMID:24740835 Esr1 Mouse triclosan multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 [Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR1 mRNA more ... CTD PMID:23261820 and PMID:29323457 Esr1 Mouse trifloxystrobin multiple interactions ISO ESR1 (Homo sapiens) 6480464 trifloxystrobin inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 Esr1 Mouse trifluralin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Trifluralin binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse trimellitic anhydride decreases expression EXP 6480464 trimellitic anhydride results in decreased expression of ESR1 mRNA CTD PMID:19042947 Esr1 Mouse triphenyl phosphate multiple interactions EXP 6480464 [tris(1 more ... CTD PMID:29112739 and PMID:32360330 Esr1 Mouse triphenyl phosphate affects expression ISO ESR1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ESR1 mRNA CTD PMID:37042841 Esr1 Mouse triphenyl phosphate increases activity ISO ESR1 (Homo sapiens) 6480464 triphenyl phosphate metabolite results in increased activity of ESR1 protein and triphenyl phosphate results in increased activity of ESR1 protein CTD PMID:24051214 more ... Esr1 Mouse triphenyl phosphate multiple interactions ISO ESR1 (Homo sapiens) 6480464 triphenyl phosphate binds to and results in increased activity of ESR1 protein CTD PMID:23398518 and PMID:33049310 Esr1 Mouse Triphenylethylene multiple interactions ISO ESR1 (Homo sapiens) 6480464 triphenylethylene binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse triptonide decreases expression EXP 6480464 triptonide results in decreased expression of ESR1 mRNA CTD PMID:33045310 Esr1 Mouse tris(2-chloroethyl) phosphate decreases activity ISO ESR1 (Homo sapiens) 6480464 tris(chloroethyl)phosphate results in decreased activity of ESR1 protein CTD PMID:24844797 Esr1 Mouse Tris(2-ethylhexyl) phosphate decreases activity ISO ESR1 (Homo sapiens) 6480464 tris(2-ethylhexyl)phosphate results in decreased activity of ESR1 protein CTD PMID:24844797 Esr1 Mouse Tris(2-ethylhexyl) phosphate multiple interactions ISO ESR1 (Homo sapiens) 6480464 tris(2-ethylhexyl)phosphate binds to and results in decreased activity of ESR1 protein CTD PMID:23398518 Esr1 Mouse triticonazole multiple interactions ISO ESR1 (Homo sapiens) 6480464 triticonazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 Esr1 Mouse trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of ESR1 mRNA CTD PMID:35537566 Esr1 Mouse tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [bisphenol A results in increased phosphorylation of ESR1 protein] CTD PMID:21813366 Esr1 Mouse tyrphostin AG 1478 multiple interactions ISO ESR1 (Homo sapiens) 6480464 ESR1 protein alternative form promotes the reaction [RTKI cpd inhibits the reaction [Estradiol results in decreased cleavage of CASP3 protein]] more ... CTD PMID:34724321 Esr1 Mouse Urolithin A multiple interactions ISO ESR1 (Homo sapiens) 6480464 3 more ... CTD PMID:16506809 Esr1 Mouse valinomycin multiple interactions ISO ESR1 (Homo sapiens) 6480464 Valinomycin binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 Esr1 Mouse valproic acid increases expression ISO ESR1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ESR1 mRNA and Valproic Acid results in increased expression of ESR1 protein CTD PMID:19772891 Esr1 Mouse valproic acid increases methylation ISO ESR1 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ESR1 gene CTD PMID:29154799 Esr1 Mouse valproic acid multiple interactions ISO ESR1 (Homo sapiens) 6480464 Valproic Acid metabolite promotes the reaction [Estradiol results in increased activity of ESR1 protein] and Valproic Acid promotes the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:23892311 Esr1 Mouse valproic acid increases activity ISO ESR1 (Homo sapiens) 6480464 Valproic Acid metabolite results in increased activity of ESR1 protein and Valproic Acid results in increased activity of ESR1 protein CTD PMID:23892311 Esr1 Mouse vinclozolin multiple interactions ISO ESR1 (Homo sapiens) 6480464 vinclozolin binds to and results in increased activity of ESR1 protein and vinclozolin inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:14579009 more ... Esr1 Mouse vinclozolin increases methylation ISO Esr1 (Rattus norvegicus) 6480464 vinclozolin results in increased methylation of ESR1 gene CTD PMID:31079544 Esr1 Mouse vinclozolin affects expression ISO Esr1 (Rattus norvegicus) 6480464 vinclozolin affects the expression of ESR1 mRNA CTD PMID:22285353 Esr1 Mouse vinclozolin affects binding ISO ESR1 (Homo sapiens) 6480464 vinclozolin binds to ESR1 protein CTD PMID:14579009 Esr1 Mouse vinclozolin increases expression ISO Esr1 (Rattus norvegicus) 6480464 vinclozolin results in increased expression of ESR1 mRNA and vinclozolin results in increased expression of ESR1 mRNA alternative form CTD PMID:17980475 and PMID:22570695 Esr1 Mouse vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of ESR1 mRNA and vinclozolin results in decreased expression of ESR1 protein CTD PMID:16504050 and PMID:36642194 Esr1 Mouse vincristine multiple interactions ISO ESR1 (Homo sapiens) 6480464 bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA] more ... CTD PMID:25752796 and PMID:35263089 Esr1 Mouse vincristine decreases expression ISO ESR1 (Homo sapiens) 6480464 Vincristine results in decreased expression of ESR1 mRNA and Vincristine results in decreased expression of ESR1 protein CTD PMID:35263089 Esr1 Mouse vinyl carbamate decreases expression EXP 6480464 vinyl carbamate results in decreased expression of ESR1 mRNA CTD PMID:17849452 Esr1 Mouse vitamin E multiple interactions ISO Esr1 (Rattus norvegicus) 6480464 Vitamin E affects the reaction [Doxorubicin affects the expression of ESR1 mRNA] CTD PMID:32810592 Esr1 Mouse vitamin E affects expression ISO Esr1 (Rattus norvegicus) 6480464 Vitamin E affects the expression of ESR1 mRNA CTD PMID:32810592 Esr1 Mouse vorinostat increases degradation ISO ESR1 (Homo sapiens) 6480464 vorinostat results in increased degradation of ESR1 protein CTD PMID:18342836 Esr1 Mouse vorinostat decreases expression ISO ESR1 (Homo sapiens) 6480464 vorinostat results in decreased expression of ESR1 mRNA CTD PMID:18342836 Esr1 Mouse vorinostat multiple interactions ISO ESR1 (Homo sapiens) 6480464 STUB1 protein promotes the reaction [Vorinostat results in increased degradation of ESR1 protein] and Vorinostat inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:18342836 and PMID:30818834 Esr1 Mouse wortmannin decreases reaction ISO Esr1 (Rattus norvegicus) 152177689 wortmannin inhibits the reaction [estrogen increases expression of Esr1 mRNA] in rat uterus RGD Esr1 Mouse xanthohumol decreases expression ISO ESR1 (Homo sapiens) 6480464 xanthohumol results in decreased expression of ESR1 protein CTD PMID:32986415 Esr1 Mouse xanthohumol multiple interactions ISO ESR1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [xanthohumol results in decreased expression of ESR1 protein] and xanthohumol promotes the reaction [Estradiol results in decreased expression of ESR1 protein] CTD PMID:32986415 Esr1 Mouse zearalenone multiple interactions ISO ESR1 (Homo sapiens) 6480464 [Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein more ... CTD PMID:12650720 more ... Esr1 Mouse zearalenone affects response to substance ISO ESR1 (Homo sapiens) 6480464 ESR1 protein affects the susceptibility to Zearalenone CTD PMID:33419253 Esr1 Mouse zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of ESR1 mRNA and Zearalenone results in decreased expression of ESR1 protein CTD PMID:27862621 more ... Esr1 Mouse zearalenone decreases expression ISO ESR1 (Homo sapiens) 6480464 Zearalenone results in decreased expression of ESR1 mRNA CTD PMID:28965971 Esr1 Mouse zearalenone increases activity ISO ESR1 (Homo sapiens) 6480464 Zearalenone metabolite results in increased activity of ESR1 protein and Zearalenone results in increased activity of ESR1 protein CTD PMID:11331656 more ... Esr1 Mouse zearalenone affects binding ISO ESR1 (Homo sapiens) 6480464 Zearalenone analog binds to ESR1 protein and Zearalenone binds to ESR1 protein CTD PMID:11162928 more ... Esr1 Mouse zearalenone multiple interactions EXP 6480464 Zearalenone binds to and results in increased activity of ESR1 protein CTD PMID:20209442 and PMID:22494775 Esr1 Mouse zearalenone affects expression ISO Esr1 (Rattus norvegicus) 6480464 Zearalenone affects the expression of ESR1 mRNA and Zearalenone affects the expression of ESR1 protein CTD PMID:22521637 and PMID:29627501 Esr1 Mouse zearalenone affects binding ISO Esr1 (Rattus norvegicus) 6480464 Zearalenone binds to ESR1 protein CTD PMID:19913605 Esr1 Mouse zearalenone affects binding EXP 6480464 Zearalenone binds to ESR1 protein CTD PMID:11162928 and PMID:19913605 Esr1 Mouse zearalenone increases activity ISO Esr1 (Rattus norvegicus) 6480464 Zearalenone results in increased activity of ESR1 protein CTD PMID:11750080 Esr1 Mouse zebularine increases expression ISO ESR1 (Homo sapiens) 6480464 pyrimidin-2-one beta-ribofuranoside results in increased expression of ESR1 mRNA CTD PMID:19459041 Esr1 Mouse zidovudine affects localization ISO Esr1 (Rattus norvegicus) 6480464 Zidovudine affects the localization of ESR1 protein CTD PMID:15531092 Esr1 Mouse zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of ESR1 protein CTD PMID:25088245 Esr1 Mouse zinc atom multiple interactions ISO ESR1 (Homo sapiens) 6480464 Zinc inhibits the reaction [Cobalt binds to ESR1 protein] CTD PMID:14640689 Esr1 Mouse zinc atom affects binding ISO ESR1 (Homo sapiens) 6480464 Zinc binds to ESR1 protein CTD PMID:14640689 Esr1 Mouse zinc oxide decreases expression EXP 6480464 Zinc Oxide results in decreased expression of ESR1 mRNA CTD PMID:33599401 Esr1 Mouse zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of ESR1 protein CTD PMID:25088245 Esr1 Mouse zinc(0) affects binding ISO ESR1 (Homo sapiens) 6480464 Zinc binds to ESR1 protein CTD PMID:14640689 Esr1 Mouse zinc(0) multiple interactions ISO ESR1 (Homo sapiens) 6480464 Zinc inhibits the reaction [Cobalt binds to ESR1 protein] CTD PMID:14640689