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Gene: Esr1 (estrogen receptor 1 (alpha)) Mus musculus
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Symbol: Esr1
Name: estrogen receptor 1 (alpha)
Description: Exhibits several functions, including chromatin binding activity; nuclear receptor activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to estradiol stimulus; mammary gland development; and reproductive structure development. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); systemic scleroderma; and vitiligo. Orthologous to human ESR1 (estrogen receptor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA420328; AU041214; C-terminally-truncated estrogen receptor alpha product-4; C-terminally-truncated estrogen receptor alpha product-5; C-terminally-truncated estrogen receptor alpha product-6; C-terminally-truncated estrogen receptor alpha product-7; ER; ER-alpha; ER[a]; ERa; ERalpha; ESR; Estr; Estra; estradiol receptor; estrogen receptor; estrogen receptor alpha variant U1; estrogen receptor alpha variant U2; Nr3a1; nuclear receptor subfamily 3 group A member 1
Orthologs:
Homo sapiens (human) : ESR1 (estrogen receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Esr1 (estrogen receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Esr1 (estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ESR1 (estrogen receptor 1)
Canis lupus familiaris (dog) : ESR1 (estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esr1 (estrogen receptor 1)
Sus scrofa (pig) : ESR1 (estrogen receptor 1)
Chlorocebus sabaeus (African green monkey) : ESR1 (estrogen receptor 1)
Heterocephalus glaber (naked mole-rat) : Esr1 (estrogen receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl104,611,593 - 5,005,614 (+)EnsemblGRCm38mm10GRCm38
GRCm38104,611,989 - 5,005,633 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37105,342,780 - 5,734,495 (-)NCBIGRCm37mm9NCBIm37
MGSCv36105,342,780 - 5,734,495 (-)NCBImm8
Celera104,553,702 - 4,949,051 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model