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Gene: Grm1 (glutamate metabotropic receptor 1) Rattus norvegicus
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Symbol: Grm1
Name: glutamate metabotropic receptor 1
Description: Exhibits G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; estrogen receptor binding activity; and identical protein binding activity. Involved in several processes, including G protein-coupled glutamate receptor signaling pathway; regulation of glutamatergic synaptic transmission; and sensory perception of pain. Localizes to the glutamatergic synapse; neuron projection; and synaptic membrane. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Orthologous to human GRM1 (glutamate metabotropic receptor 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; glutamate signaling pathway; Huntington's disease pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-3,5-dihydroxyphenylglycine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; glutamate receptor, metabotropic 1; Gprc1a; metabotropic glutamate receptor 1; mGluR1
Orthologs:
Homo sapiens (human) : GRM1 (glutamate metabotropic receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Grm1 (glutamate receptor, metabotropic 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm1 (glutamate metabotropic receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM1 (glutamate metabotropic receptor 1)
Canis lupus familiaris (dog) : GRM1 (glutamate metabotropic receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm1 (glutamate metabotropic receptor 1)
Sus scrofa (pig) : GRM1 (glutamate metabotropic receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014,753,141 - 5,165,859 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.016,815,959 - 6,818,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.016,413,420 - 6,685,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415,318,617 - 5,744,593 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115,318,616 - 5,744,590 (-)NCBI
Celera13,589,875 - 3,976,624 (-)NCBICelera
Cytogenetic Map1p13NCBI
SHRSP x BN Map15.6799RGD
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
  
More on Grm1
Alliance Gene
NCBI Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2742
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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