Ptgs2 (prostaglandin-endoperoxide synthase 2) - Rat Genome Database
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Gene: Ptgs2 (prostaglandin-endoperoxide synthase 2) Mus musculus
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Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
RGD ID: 731007
Description: Exhibits heme binding activity; prostaglandin-endoperoxide synthase activity; and protein homodimerization activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cellular metabolic process; and regulation of inflammatory response. Localizes to cytoplasm; neuron projection; and nuclear membrane. Predicted to colocalize with caveola. Is expressed in several structures, including cochlea; early embryo; lung; nervous system; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; artery disease (multiple); arthritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: COX; Cox-; Cox-2; COX2; cyclooxygenase 2; cyclooxygenase-2; glucocorticoid-regulated inflammatory cyclooxygenase; gripghs; macrophage activation-associated marker protein P71/73; PES-2; Pgh; PGH synthase 2; PGHS; PGHS-2; Pghs2; PHS; PHS II; PHS-2; prostaglandin G/H synthase 2; prostaglandin H2 synthase 2; Tis; TIS10
Orthologs:
Homo sapiens (human) : PTGS2 (prostaglandin-endoperoxide synthase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptgs2 (prostaglandin-endoperoxide synthase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Canis lupus familiaris (dog) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Sus scrofa (pig) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Chlorocebus sabaeus (African green monkey) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Heterocephalus glaber (naked mole-rat) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
more info ...
Related Pseudogenes: Gm13033  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391149,975,782 - 149,983,985 (+)NCBI
GRCm381150,100,031 - 150,108,234 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,100,031 - 150,108,227 (+)EnsemblGRCm38mm10GRCm38
MGSCv371151,947,254 - 151,955,147 (+)NCBIGRCm37mm9NCBIm37
MGSCv361151,862,342 - 151,870,235 (+)NCBImm8
Celera1152,546,728 - 152,554,611 (+)NCBICelera
Cytogenetic Map1G1NCBI
cM Map163.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model