Lbp (lipopolysaccharide binding protein) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Lbp (lipopolysaccharide binding protein) Mus musculus
Analyze
Symbol: Lbp
Name: lipopolysaccharide binding protein
RGD ID: 62157
MGI Page MGI
Description: Enables lipopolysaccharide binding activity and signaling receptor binding activity. Involved in several processes, including positive regulation of respiratory burst involved in inflammatory response; positive regulation of tumor necrosis factor production; and response to bacterium. Acts upstream of or within leukocyte chemotaxis involved in inflammatory response; positive regulation of chemokine production; and positive regulation of neutrophil chemotaxis. Located in cell surface and extracellular space. Is expressed in brain; heart ventricle; liver lobe; and reproductive system. Orthologous to human LBP (lipopolysaccharide binding protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Bpif; Bpifd2; lipopolysaccharide-binding protein; Ly88
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,148,413 - 158,174,772 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,148,413 - 158,174,772 (+)EnsemblGRCm39 Ensembl
GRCm382158,306,493 - 158,332,852 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,306,493 - 158,332,852 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,132,229 - 158,158,588 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,997,986 - 158,023,737 (+)NCBIMGSCv36mm8
Celera2164,244,570 - 164,269,152 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (EXP,ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-amanitin  (EXP)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acids  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
atazanavir sulfate  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzylpenicillin  (EXP)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloroform  (ISO)
ciguatoxin CTX1B  (EXP)
cobalt dichloride  (ISO)
crocidolite asbestos  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (EXP)
diiodine  (EXP)
dimethylarsinic acid  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
erythromycin A  (EXP)
erythromycin estolate  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
flutamide  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (EXP,ISO)
Ginkgolide A  (EXP)
glafenine  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
graphene oxide  (EXP)
indometacin  (ISO)
isoprenaline  (EXP)
ketamine  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
levofloxacin  (ISO)
lipopolysaccharide  (EXP,ISO)
menadione  (EXP)
methimazole  (ISO)
methotrexate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naloxone  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
Nonylphenol  (ISO)
O-methyleugenol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenacetin  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phenylhydrazine  (ISO)
pipoxolan  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quinidine  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
senecionine  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sulindac  (ISO)
Sunset Yellow FCF  (ISO)
tacrolimus hydrate  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
theophylline  (ISO)
tolcapone  (ISO)
trichloroethene  (ISO)
triptonide  (EXP)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IDA,ISO)
extracellular space  (IBA,IDA,ISO)
membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Lipopolysaccharide-binding protein and lipopolysaccharide receptor CD14 gene expression after thermal injury and its potential mechanism(s). Fang CW, etal., J Trauma. 2002 Nov;53(5):957-67.
2. Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats. Fang H, etal., J Immunol Methods. 2012 Aug 31;382(1-2):68-75. doi: 10.1016/j.jim.2012.05.006. Epub 2012 May 8.
3. Induction of hepatocyte lipopolysaccharide binding protein in models of sepsis and the acute-phase response. Geller DA, etal., Arch Surg. 1993 Jan;128(1):22-7; discussion 27-8.
4. Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat. Hassanali Z, etal., Diabetes Obes Metab. 2010 Feb;12(2):139-47. doi: 10.1111/j.1463-1326.2009.01130.x. Epub 2009 Nov 16.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Activity of lipopolysaccharide-binding protein-bactericidal/permeability-increasing protein fusion peptide in an experimental model of Pseudomonas sepsis. Opal SM, etal., Antimicrob Agents Chemother. 1995 Dec;39(12):2813-5.
10. Myeloid differentiation 2 as a therapeutic target of inflammatory disorders. Park SH, etal., Pharmacol Ther. 2012 Mar;133(3):291-8. doi: 10.1016/j.pharmthera.2011.11.001. Epub 2011 Nov 19.
11. Puerarin ameliorates experimental alcoholic liver injury by inhibition of endotoxin gut leakage, Kupffer cell activation, and endotoxin receptors expression. Peng JH, etal., J Pharmacol Exp Ther. 2013 Mar;344(3):646-54. doi: 10.1124/jpet.112.201137. Epub 2012 Dec 31.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Altered gene expression in gingival tissues and enhanced bone loss in rats with diabetes with experimental periodontitis. Soboku K, etal., J Periodontol. 2014 Mar;85(3):455-64. doi: 10.1902/jop.2013.120705. Epub 2013 Jun 3.
18. High-density lipoprotein administration attenuates liver proinflammatory response, restores liver endothelial nitric oxide synthase activity, and lowers portal pressure in cirrhotic rats. Thabut D, etal., Hepatology. 2007 Dec;46(6):1893-906.
19. The Kinetic Expression of Lipopolysaccharide-Binding Protein and CD14 Gene in Obstructive Jaundice. Tsai CH, etal., J Invest Surg. 2014 Aug 5.
20. Activation of the lipopolysaccharide signaling pathway in hepatic transplantation preservation injury. Tsoulfas G, etal., Transplantation. 2002 Jul 15;74(1):7-13.
21. LBP inhibitory peptide reduces endotoxin-induced macrophage activation and mortality. Wu X, etal., Inflamm Res. 2005 Nov;54(11):451-7.
22. [Role of endotoxin translocation on mesenteric lymph reperfusion aggravating multiple organ injury in SMAO shock rats]. Yang LN, etal., Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2012 Jan;28(1):74-8.
Additional References at PubMed
PMID:8889548   PMID:9144073   PMID:9338787   PMID:9396775   PMID:10047547   PMID:10349636   PMID:10380702   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11079463   PMID:11160257  
PMID:11217851   PMID:11466385   PMID:11705897   PMID:11884468   PMID:12055258   PMID:12353926   PMID:12370383   PMID:12477932   PMID:12932360   PMID:14610273   PMID:14638760   PMID:15356561  
PMID:15452020   PMID:15489334   PMID:15619225   PMID:15769905   PMID:15993364   PMID:16141072   PMID:16141073   PMID:16163057   PMID:16439470   PMID:16493079   PMID:16602821   PMID:16614372  
PMID:17442982   PMID:18292574   PMID:18554416   PMID:18559343   PMID:18948440   PMID:19022463   PMID:19234712   PMID:20833181   PMID:21267068   PMID:21308778   PMID:21787333   PMID:21873635  
PMID:21993208   PMID:24194600   PMID:24380872   PMID:24664302   PMID:24671012   PMID:26201685   PMID:26332085   PMID:26431947   PMID:27344313   PMID:27404046   PMID:27626380   PMID:32090603  
PMID:36410673   PMID:36710409   PMID:37789385   PMID:37914098   PMID:38355793  


Genomics

Comparative Map Data
Lbp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,148,413 - 158,174,772 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,148,413 - 158,174,772 (+)EnsemblGRCm39 Ensembl
GRCm382158,306,493 - 158,332,852 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,306,493 - 158,332,852 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,132,229 - 158,158,588 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,997,986 - 158,023,737 (+)NCBIMGSCv36mm8
Celera2164,244,570 - 164,269,152 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
LBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,346,482 - 38,377,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,346,482 - 38,377,013 (+)EnsemblGRCh38hg38GRCh38
GRCh372036,974,885 - 37,005,655 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,408,299 - 36,439,067 (+)NCBINCBI36Build 36hg18NCBI36
Build 342036,408,298 - 36,439,067NCBI
Celera2033,683,680 - 33,714,456 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,709,729 - 33,740,760 (+)NCBIHuRef
CHM1_12036,878,602 - 36,909,384 (+)NCBICHM1_1
T2T-CHM13v2.02040,072,800 - 40,104,597 (+)NCBIT2T-CHM13v2.0
Lbp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,373,786 - 167,400,941 (+)NCBIGRCr8
mRatBN7.23146,953,889 - 146,981,032 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,954,015 - 146,981,586 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,786,436 - 150,813,463 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,285,723 - 159,312,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03157,020,490 - 157,047,489 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,786,232 - 154,812,910 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,786,215 - 154,813,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03160,793,301 - 160,819,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43149,016,605 - 149,043,530 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,922,500 - 148,949,992 (+)NCBI
Celera3145,655,280 - 145,682,077 (+)NCBICelera
Cytogenetic Map3q42NCBI
LBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,070,881 - 44,103,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12044,063,979 - 44,096,876 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,670,128 - 34,703,046 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,780,768 - 35,813,188 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,780,768 - 35,813,188 (+)Ensemblpanpan1.1panPan2
LBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,810,369 - 26,833,515 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,809,843 - 26,833,434 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,456,134 - 26,479,256 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02427,506,422 - 27,529,551 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,506,460 - 27,529,472 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,780,778 - 26,803,800 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,888,642 - 26,911,780 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,377,130 - 27,400,265 (+)NCBIUU_Cfam_GSD_1.0
Lbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,713,998 - 175,732,560 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,016,926 - 3,035,552 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,017,471 - 3,035,481 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,393,818 - 41,429,551 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11741,398,935 - 41,429,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,838,042 - 46,868,577 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,375,364 - 25,407,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,374,755 - 25,406,839 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605074,213,568 - 74,246,762 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lbp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248421,301,831 - 1,332,346 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248421,306,299 - 1,332,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1028
Count of miRNA genes:596
Interacting mature miRNAs:715
Transcripts:ENSMUST00000016168, ENSMUST00000109491, ENSMUST00000129811, ENSMUST00000146600, ENSMUST00000152541
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
13825247Agoc2_magouti coat color QTL 2 (mouse)2151841920159841920Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155823920181755017Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1558842Tailq2_mtail length QTL 2 (mouse)Not determined2151640941162737074Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
10412080Hylaq2_mHyperlocomotor activity related QTL 2 (mouse)Not determined2151640941164119146Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1357862Epfq1_mepididymal fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158078337178442452Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301588Hrec_mhemotopoietic response to early cytokines (mouse)Not determined2154553217159428450Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1558852Gnf2_mgrowth and fatness 2 (mouse)Not determined2152699221162197085Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143773445160303008Mouse
1357772Scfq1_msubcutaneous fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
13504830Bacsq1_mbaculum shape QTL 1 (mouse)2145716184161016184Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156196464181755017Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse

Markers in Region
X99347  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382158,332,105 - 158,332,231UniSTSGRCm38
MGSCv372158,157,841 - 158,157,967UniSTSGRCm37
Celera2164,268,403 - 164,268,529UniSTS
Cytogenetic Map2H1UniSTS
cM Map283.0UniSTS
Whitehead/MRC_RH21830.45UniSTS
UniSTS:224839  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382158,332,081 - 158,332,229UniSTSGRCm38
MGSCv372158,157,817 - 158,157,965UniSTSGRCm37
Celera2164,268,379 - 164,268,527UniSTS
Cytogenetic Map2H1UniSTS
cM Map283.0UniSTS
Lbp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H1UniSTS
cM Map283.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000016168   ⟹   ENSMUSP00000016168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2158,148,413 - 158,174,772 (+)Ensembl
GRCm38.p6 Ensembl2158,306,493 - 158,332,852 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109491   ⟹   ENSMUSP00000105117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2158,148,413 - 158,152,426 (+)Ensembl
GRCm38.p6 Ensembl2158,306,493 - 158,310,506 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129811   ⟹   ENSMUSP00000118297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2158,156,126 - 158,166,562 (+)Ensembl
GRCm38.p6 Ensembl2158,314,206 - 158,324,642 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146600
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2158,148,532 - 158,160,533 (+)Ensembl
GRCm38.p6 Ensembl2158,306,612 - 158,318,613 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152541
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2158,148,413 - 158,162,876 (+)Ensembl
GRCm38.p6 Ensembl2158,306,493 - 158,320,956 (+)Ensembl
RefSeq Acc Id: NM_008489   ⟹   NP_032515
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392158,148,413 - 158,174,772 (+)NCBI
GRCm382158,306,493 - 158,332,852 (+)ENTREZGENE
MGSCv372158,132,229 - 158,158,588 (+)RGD
Celera2164,244,570 - 164,269,152 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032515 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH04795 (Get FASTA)   NCBI Sequence Viewer  
  CAA67727 (Get FASTA)   NCBI Sequence Viewer  
  EDL06262 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000016168
  ENSMUSP00000016168.3
  ENSMUSP00000105117.2
  ENSMUSP00000118297.2
GenBank Protein Q61805 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032515   ⟸   NM_008489
- Peptide Label: precursor
- UniProtKB: A2AC66 (UniProtKB/Swiss-Prot),   Q99KA0 (UniProtKB/Swiss-Prot),   Q61805 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000118297   ⟸   ENSMUST00000129811
Ensembl Acc Id: ENSMUSP00000016168   ⟸   ENSMUST00000016168
Ensembl Acc Id: ENSMUSP00000105117   ⟸   ENSMUST00000109491
Protein Domains
Lipid-binding serum glycoprotein C-terminal   Lipid-binding serum glycoprotein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61805-F1-model_v2 AlphaFold Q61805 1-481 view protein structure

Promoters
RGD ID:6831686
Promoter ID:MM_KWN:32726
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung
Transcripts:ENSMUST00000109491,   NM_008489,   OTTMUST00000037891,   UC008NPY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362158,132,289 - 158,132,789 (+)MPROMDB
RGD ID:6879492
Promoter ID:EPDNEW_M3197
Type:multiple initiation site
Name:Lbp_1
Description:Mus musculus lipopolysaccharide binding protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382158,306,639 - 158,306,699EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1098776 AgrOrtholog
Ensembl Genes ENSMUSG00000016024 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000016168 ENTREZGENE
  ENSMUST00000016168.9 UniProtKB/Swiss-Prot
  ENSMUST00000109491.8 UniProtKB/TrEMBL
  ENSMUST00000129811.2 UniProtKB/TrEMBL
InterPro Bactericidal_perm-incr_a/b_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BPI/LBP UniProtKB/Swiss-Prot
  BPI/LBP/Plunc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16803 UniProtKB/Swiss-Prot
MGD MGI:1098776 ENTREZGENE
NCBI Gene 16803 ENTREZGENE
PANTHER PTHR10504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10504:SF66 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LBP_BPI_CETP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LBP_BPI_CETP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lbp PhenoGen
PIRSF Lipid_binding_protein UniProtKB/Swiss-Prot
PROSITE LBP_BPI_CETP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BPI1 UniProtKB/Swiss-Prot
  BPI2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF55394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AC65_MOUSE UniProtKB/TrEMBL
  A2AC66 ENTREZGENE
  F6XKX9_MOUSE UniProtKB/TrEMBL
  LBP_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q99KA0 ENTREZGENE
UniProt Secondary A2AC66 UniProtKB/Swiss-Prot
  Q99KA0 UniProtKB/Swiss-Prot