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Gene: LBP (lipopolysaccharide binding protein) Homo sapiens
Symbol: LBP
Name: lipopolysaccharide binding protein
Description: Exhibits lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of toll-like receptor 4 signaling pathway; and response to bacterium. Localizes to cell surface and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BPI fold containing family D, member 2; BPIFD2; lipopolysaccharide-binding protein; LPS-binding protein; MGC22233
Mus musculus (house mouse) : Lbp (lipopolysaccharide binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lbp (lipopolysaccharide binding protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LBP (lipopolysaccharide binding protein)
Canis lupus familiaris (dog) : LBP (lipopolysaccharide binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lbp (lipopolysaccharide binding protein)
Sus scrofa (pig) : LBP (lipopolysaccharide binding protein)
Chlorocebus sabaeus (African green monkey) : LBP (lipopolysaccharide binding protein)
Heterocephalus glaber (naked mole-rat) : Lbp (lipopolysaccharide binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2038,346,482 - 38,377,013 (+)EnsemblGRCh38hg38GRCh38
GRCh382038,346,482 - 38,377,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372036,974,814 - 37,005,653 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,408,299 - 36,439,067 (+)NCBINCBI36hg18NCBI36
Build 342036,408,298 - 36,439,067NCBI
Celera2033,683,680 - 33,714,456 (+)NCBI
Cytogenetic Map20q11.23NCBI
HuRef2033,709,729 - 33,740,760 (+)NCBIHuRef
CHM1_12036,878,602 - 36,909,384 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LBP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347766
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.