Slc13a3 (solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Slc13a3 (solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3) Mus musculus
Analyze
Symbol: Slc13a3
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
RGD ID: 69658
MGI Page MGI
Description: Is expressed in central nervous system; esophagus; genitourinary system; liver; and retina. Orthologous to human SLC13A3 (solute carrier family 13 member 3); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: mNaDC3; Na(+)/dicarboxylate cotransporter 3; NaD; NaDC; NaDC-3; NaDC3; SDCT; SDCT2; sodium-dependent high-affinity dicarboxylate transporter 2; solute carrier family 13 member 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,247,215 - 165,315,117 (-)NCBIGRCm39mm39
GRCm39 Ensembl2165,246,948 - 165,315,150 (-)Ensembl
GRCm382165,405,295 - 165,473,197 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,405,028 - 165,473,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,230,795 - 165,298,697 (-)NCBIGRCm37mm9NCBIm37
MGSCv362165,096,500 - 165,164,402 (-)NCBImm8
Celera2171,347,492 - 171,415,775 (-)NCBICelera
Cytogenetic Map2H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,3-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyproconazole  (EXP)
dexamethasone  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
ether  (ISO)
flutamide  (ISO)
folic acid  (EXP)
glafenine  (ISO)
glyphosate  (ISO)
graphite  (ISO)
GW 4064  (EXP)
indole-3-methanol  (ISO)
isoflurane  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
levofloxacin  (ISO)
lipopolysaccharide  (EXP)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
paracetamol  (EXP,ISO)
pentobarbital  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pravastatin  (EXP)
propanal  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
succinic acid  (EXP,ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
toluene  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11287335   PMID:11870364   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17356845  
PMID:18287559   PMID:19521566   PMID:21267068   PMID:21386911   PMID:21677750   PMID:21873635   PMID:24194600   PMID:26176240   PMID:27626380   PMID:31492896  


Genomics

Comparative Map Data
Slc13a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,247,215 - 165,315,117 (-)NCBIGRCm39mm39
GRCm39 Ensembl2165,246,948 - 165,315,150 (-)Ensembl
GRCm382165,405,295 - 165,473,197 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,405,028 - 165,473,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,230,795 - 165,298,697 (-)NCBIGRCm37mm9NCBIm37
MGSCv362165,096,500 - 165,164,402 (-)NCBImm8
Celera2171,347,492 - 171,415,775 (-)NCBICelera
Cytogenetic Map2H3NCBI
SLC13A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2046,557,823 - 46,684,467 (-)EnsemblGRCh38hg38GRCh38
GRCh382046,557,828 - 46,684,485 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372045,186,467 - 45,313,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,619,870 - 44,746,514 (-)NCBINCBI36hg18NCBI36
Build 342044,619,869 - 44,713,505NCBI
Celera2041,897,908 - 42,024,605 (-)NCBI
Cytogenetic Map20q13.12ENTREZGENE
HuRef2041,927,384 - 42,054,359 (-)NCBIHuRef
CHM1_12045,089,076 - 45,216,112 (-)NCBICHM1_1
Slc13a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23154,141,878 - 154,204,604 (-)NCBI
Rnor_6.0 Ensembl3162,084,315 - 162,147,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03162,084,336 - 162,147,398 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03168,266,585 - 168,329,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,447,900 - 156,510,620 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13156,353,929 - 156,416,658 (-)NCBI
Celera3152,740,642 - 152,803,198 (-)NCBICelera
Cytogenetic Map3q42NCBI
Slc13a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,755,312 - 10,831,900 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,755,336 - 10,829,797 (+)NCBIChiLan1.0ChiLan1.0
SLC13A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12043,975,373 - 44,101,788 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,977,568 - 44,068,886 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02042,890,251 - 43,018,635 (-)NCBIMhudiblu_PPA_v0panPan3
SLC13A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2433,809,731 - 33,884,139 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12433,810,594 - 33,884,169 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc13a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365146,554,605 - 6,594,014 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC13A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,714,183 - 48,815,123 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,714,180 - 48,792,280 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21754,563,504 - 54,593,504 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC13A3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,233,287 - 17,324,761 (+)NCBI
ChlSab1.1 Ensembl217,233,346 - 17,324,951 (+)Ensembl
Slc13a3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247908,028,054 - 8,104,123 (+)NCBI

Position Markers
D2S2063  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382165,446,715 - 165,446,970UniSTSGRCm38
MGSCv372165,272,215 - 165,272,470UniSTSGRCm37
Celera2171,389,014 - 171,389,269UniSTS
Cytogenetic Map2H3UniSTS
D2Mit288  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382165,447,193 - 165,447,391UniSTSGRCm38
MGSCv372165,272,693 - 165,272,891UniSTSGRCm37
Celera2171,389,492 - 171,389,691UniSTS
Cytogenetic Map2H3UniSTS
cM Map298.0UniSTS
Whitehead Genetic283.1UniSTS
Whitehead/MRC_RH21886.25UniSTS
Slc13a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS
cM Map285.54UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163844614182113224Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145676855179677006Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2118112449174483070Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132182239166182410Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162791700182113224Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152857301169276004Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145355029179355165Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142751556178800659Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145386799179386921Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162895006178800659Mouse
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135857301169857441Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162895006178800659Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2139124680173124809Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144673941181254801Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155982127182113224Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156354671182113224Mouse
1300676Prdt2_mprion disease incubation time 2 (mouse)Not determined2164873361182113224Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158236417178800659Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2150146982182113224Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151936377182113224Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163844614182113224Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150370301182113224Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143931525165823099Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149394987182113224Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143931525169276004Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148822973182113224Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135857301169857441Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285893925181254801Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135857301169857441Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135857301169857441Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150370301182113224Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142586427176586530Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150370301182113224Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148396284182113224Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133302991167303138Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133302991167303138Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151867353174547331Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152487900182113224Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124600000168400000Mouse
12801461Intim1_mintima modifier 1 (mouse)2142586427176586530Mouse
11353826Bdln10_mbody length 10 (mouse)2140599562174599562Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135590624173607823Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103265371167370436Mouse
12910810Pwbwq2_mpre-weaning body weight QTL 2 (mouse)2160769245169952882Mouse
12910800Pwgrq3_mpre-weaning growth rate QTL 3 (mouse)2160769245169952882Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1937
Count of miRNA genes:611
Interacting mature miRNAs:764
Transcripts:ENSMUST00000029208, ENSMUST00000109279, ENSMUST00000143136, ENSMUST00000145513, ENSMUST00000147107
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000029208   ⟹   ENSMUSP00000029208
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2165,405,028 - 165,473,230 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109279   ⟹   ENSMUSP00000104902
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2165,405,295 - 165,473,230 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143136
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2165,411,884 - 165,420,293 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145513
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2165,406,705 - 165,409,066 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147107
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2165,444,103 - 165,473,199 (-)Ensembl
RefSeq Acc Id: NM_054055   ⟹   NP_473396
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392165,247,215 - 165,315,117 (-)NCBI
GRCm382165,405,295 - 165,473,197 (-)NCBI
MGSCv372165,230,795 - 165,298,697 (-)RGD
Celera2171,347,492 - 171,415,775 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_473396   ⟸   NM_054055
- UniProtKB: Q91Y63 (UniProtKB/Swiss-Prot),   Q3UUJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029208   ⟸   ENSMUST00000029208
RefSeq Acc Id: ENSMUSP00000104902   ⟸   ENSMUST00000109279

Promoters
RGD ID:6832719
Promoter ID:MM_KWN:33007
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000040181
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362165,234,501 - 165,235,252 (-)MPROMDB
RGD ID:6832715
Promoter ID:MM_KWN:33010
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney
Transcripts:OTTMUST00000002317,   OTTMUST00000040179,   OTTMUST00000040180
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362165,298,356 - 165,298,856 (-)MPROMDB
RGD ID:6879732
Promoter ID:EPDNEW_M3317
Type:multiple initiation site
Name:Slc13a3_1
Description:Mus musculus solute carrier family 13 (sodium-dependent dicarboxylatetransporter), member 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382165,473,194 - 165,473,254EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2149635 AgrOrtholog
Ensembl Genes ENSMUSG00000018459 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000029208 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000104902 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029208 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000109279 UniProtKB/TrEMBL
InterPro SLC13A/DASS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:114644 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2149635 ENTREZGENE
NCBI Gene 114644 ENTREZGENE
Pfam Na_sulph_symp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc13a3 PhenoGen
UniProt A2A4U9_MOUSE UniProtKB/TrEMBL
  Q3UUJ6 ENTREZGENE, UniProtKB/TrEMBL
  Q91Y63 ENTREZGENE, UniProtKB/Swiss-Prot