Cxcl2 (C-X-C motif chemokine ligand 2) - Rat Genome Database

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Gene: Cxcl2 (C-X-C motif chemokine ligand 2) Mus musculus
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Symbol: Cxcl2
Name: C-X-C motif chemokine ligand 2 (Ensembl:chemokine (C-X-C motif) ligand 2)
RGD ID: 733118
MGI Page MGI
Description: Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Involved in response to molecule of bacterial origin. Located in extracellular space. Is expressed in several structures, including embryo mesenchyme; floor plate; gut; respiratory system; and skin. Orthologous to several human genes including CXCL3 (C-X-C motif chemokine ligand 3).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-X-C motif chemokine 2; chemokine (C-X-C motif) ligand 2; CINC; CINC-2a; Gr; Gro2; GROb; macrophage inflammatory protein 2; Mgsa; Mgsa-b; Mi; MIP; MIP-2; MIP-2a; Mip2; Scy; Scyb; Scyb2; small inducible cytokine subfamily, member 2
RGD Orthologs
Human
Rat
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,051,758 - 91,053,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl591,051,730 - 91,053,797 (+)EnsemblGRCm39 Ensembl
GRCm38590,903,899 - 90,905,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,332,925 - 91,334,964 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,979,099 - 91,981,138 (+)NCBIMGSCv36mm8
Celera589,048,217 - 89,050,256 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid  (EXP)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (EXP)
(E)-cinnamyl alcohol  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,3-benzothiazole-2-thiol  (EXP)
1,4-phenylenediamine  (EXP)
1,7-dimethylxanthine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
13,14-dihydro-15-ketoprostaglandin D2  (EXP)
15-acetyldeoxynivalenol  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2''-galloylhyperin  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (EXP,ISO)
2-naphthylamine  (ISO)
2-tert-butylhydroquinone  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-aminobenzamide  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methyladenine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitroquinoline N-oxide  (EXP)
5-fluorouracil  (EXP)
6alpha-methylprednisolone  (ISO)
acrolein  (EXP)
Actein  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin G1  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP)
alpha-hexylcinnamaldehyde  (EXP)
amiloride  (EXP)
amiodarone  (EXP)
amitrole  (ISO)
amlexanox  (EXP)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
amphibole asbestos  (ISO)
amphotericin B  (ISO)
ampicillin  (EXP)
andrographolide  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antirheumatic drug  (ISO)
argatroban  (EXP)
aripiprazole  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
asbestos  (EXP)
asperentin  (EXP)
ATP  (EXP)
azathioprine  (EXP)
azetidine  (EXP)
Bardoxolone methyl  (EXP,ISO)
benzalkonium chloride  (EXP)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (EXP)
beta-D-glucosamine  (ISO)
beta-eudesmol  (EXP)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP,ISO)
boron nitride  (ISO)
bortezomib  (EXP,ISO)
Botulinum toxin type A  (EXP)
Brevianamide A  (EXP)
budesonide  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
calcitriol  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
carrageenan  (EXP,ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (EXP)
chloroethene  (EXP)
chlorothalonil  (ISO)
cholesterol  (ISO)
choline  (EXP)
chondroitin sulfate  (ISO)
cinnamyl alcohol  (EXP)
ciprofloxacin  (EXP)
cirsilineol  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
citral  (EXP)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corosolic acid  (EXP)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
D-glucose  (EXP)
dantrolene  (EXP)
decabromodiphenyl ether  (ISO)
Decursin  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (EXP)
diflorasone  (EXP)
dimercaprol  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
divanadium pentaoxide  (EXP)
dizocilpine maleate  (EXP)
dobutamine  (EXP)
domperidone  (EXP)
dopexamine  (EXP)
doxorubicin  (ISO)
edaravone  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
endosulfan  (ISO)
enflurane  (ISO)
ethanol  (EXP,ISO)
ethylene glycol dimethacrylate  (EXP)
excitatory amino acid agonist  (EXP)
ferroheme b  (EXP)
flavonoids  (ISO)
flucloxacillin  (EXP)
flutamide  (EXP)
fomepizole  (ISO)
fulvestrant  (EXP,ISO)
fumonisin B1  (ISO)
furan  (ISO)
Fusarenone X  (EXP)
gadolinium trichloride  (EXP,ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
geranial  (EXP)
glucose  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
graphene oxide  (EXP)
graphite  (ISO)
halothane  (EXP,ISO)
heme b  (EXP)
heparin  (ISO)
hexadecanoic acid  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (EXP,ISO)
ibuprofen  (EXP,ISO)
imidurea  (EXP)
indometacin  (EXP,ISO)
iron atom  (ISO)
iron trichloride  (ISO)
iron(0)  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
isoeugenol  (EXP)
isoflurane  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lipoxin A4  (EXP)
lithocholic acid  (EXP)
LY294002  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
manganese(II) sulfate  (ISO)
maslinic acid  (EXP)
mercaptopurine  (ISO)
mercury dichloride  (ISO)
metacetamol  (EXP)
metformin  (EXP)
methamphetamine  (EXP,ISO)
methimazole  (EXP,ISO)
methotrexate  (ISO)
methyl methacrylate  (EXP)
methyl salicylate  (EXP)
methylmercury chloride  (EXP,ISO)
metoclopramide  (EXP)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP)
Muraglitazar  (ISO)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
naproxen  (ISO)
naringin  (EXP)
neocuproine  (EXP)
neoechinulin A  (EXP)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nitrofen  (ISO)
nitrogen dioxide  (EXP,ISO)
Nivalenol  (EXP)
nonivamide  (EXP)
o-anisidine  (ISO)
obeticholic acid  (EXP)
olaparib  (EXP)
oleanolic acid  (EXP)
oleic acid  (ISO)
oligopeptide  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parthenolide  (EXP)
pentanal  (ISO)
Pentoxifylline  (ISO)
peptidoglycan  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phalloidin  (EXP)
phenanthridone  (EXP)
phenobarbital  (ISO)
phenytoin  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
poly(I:C)  (ISO)
polymyxin B2  (ISO)
pravastatin  (EXP,ISO)
prednisolone  (ISO)
Primycin  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
propan-2-ol  (EXP)
propanal  (ISO)
prostaglandin D2  (EXP)
prostaglandin E1  (EXP)
purine-6-thiol  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinomethionate  (ISO)
rac-lactic acid  (EXP,ISO)
raloxifene  (ISO)
ranitidine  (ISO)
reactive oxygen species  (ISO)
resolvin D1  (EXP)
resolvin D2  (EXP)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
ritonavir  (ISO)
Roridin A  (EXP)
rotenone  (ISO)
ryanodine  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
salicylic acid  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (EXP)
selenium atom  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium dodecyl sulfate  (EXP)
sterigmatocystin  (EXP)
styrene  (EXP)
succimer  (EXP)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sumatriptan  (ISO)
tamoxifen  (ISO)
tauro-beta-muricholic acid  (EXP)
taurocholic acid  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetradecane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP,ISO)
Tiron  (EXP)
titanium dioxide  (EXP,ISO)
TMC-120A  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (ISO)
trans-isoeugenol  (EXP)
triadimefon  (ISO)
trichostatin A  (ISO)
triclosan  (EXP)
trimellitic anhydride  (EXP)
Triptolide  (EXP)
troglitazone  (EXP,ISO)
tropisetron  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
UDP  (EXP)
undecane  (ISO)
ursodeoxycholic acid  (EXP)
ursolic acid  (EXP)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
vitamin D  (EXP)
wortmannin  (ISO)
XL147  (EXP)
zaragozic acid A  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Role of cytokine-induced neutrophil chemoattractant-2 (CINC-2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa. Amano H, etal., Cytokine. 2000 Nov;12(11):1662-8.
2. Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. Bauer CM, etal., PLoS One. 2010 Oct 12;5(10):e13251.
3. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. Blanco-Melo D, etal., Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
4. Ischemia-reperfusion of rat myocardium activates nuclear factor-KappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine. Chandrasekar B, etal., Circulation. 2001 May 8;103(18):2296-302.
5. Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. Chiang CH, etal., Intensive Care Med. 2011 May 27.
6. Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro. Colletti LM and Green M, Shock. 2001 Oct;16(4):312-9.
7. The ratio of ELR+ to ELR- CXC chemokines affects the lung and liver injury following hepatic ischemia/ reperfusion in the rat. Colletti LM, etal., Hepatology. 2000 Feb;31(2):435-45.
8. [Role of early growth response factor-1 signal pathway in acute intrahepatic cholestatic hepatic injury in rats]. Ding Y, etal., Zhonghua Gan Zang Bing Za Zhi. 2008 Mar;16(3):215-9.
9. Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10. Fine JS, etal., Inflammation. 2003 Aug;27(4):161-74.
10. Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans. Fujita T, etal., Biochem Pharmacol. 2010 May 15;79(10):1496-505. Epub 2010 Jan 22.
11. Characterization of the inflammatory response during acute and post-acute phases after severe burn. Gauglitz GG, etal., Shock. 2008 Nov;30(5):503-7.
12. Differential host gene responses in mice infected with two highly pathogenic avian influenza viruses of subtype H5N1 isolated from wild birds in Thailand. Hayashi T, etal., Virology. 2011 Mar 30;412(1):9-18. Epub 2011 Jan 19.
13. Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1. Hsu JT, etal., Am J Physiol Regul Integr Comp Physiol. 2008 Jun;294(6):R1825-31. Epub 2008 Apr 23.
14. Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats. Hsu KY, etal., J Surg Res. 2011 May 15;167(2):e255-62. Epub 2010 Apr 24.
15. Vitamin A and retinoic acid act synergistically to increase lung retinyl esters during normoxia and reduce hyperoxic lung injury in newborn mice. James ML, etal., Pediatr Res. 2010 Jun;67(6):591-7.
16. Transcriptional profiling of lipopolysaccharide-induced acute lung injury. Jeyaseelan S, etal., Infect Immun. 2004 Dec;72(12):7247-56.
17. Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-delta (delta-PKC). Kilpatrick LE, etal., J Leukoc Biol. 2011 Jan;89(1):3-10. Epub 2010 Aug 19.
18. Role of neutrophils and NADPH phagocyte oxidase in host defense against respiratory infection with virulent Francisella tularensis in mice. KuoLee R, etal., Microbes Infect. 2011 May;13(5):447-56. Epub 2011 Jan 26.
19. Blockade of cysteine-rich protein 61 attenuates renal inflammation and fibrosis after ischemic kidney injury. Lai CF, etal., Am J Physiol Renal Physiol. 2014 Sep 1;307(5):F581-92. doi: 10.1152/ajprenal.00670.2013. Epub 2014 Jun 11.
20. The role of keratinocyte-derived chemokine in hemorrhage-induced acute lung injury in mice. Lee BH, etal., J Korean Med Sci. 2009 Oct;24(5):775-81. Epub 2009 Sep 23.
21. Effect of glucocorticoid pretreatment on oxidative liver injury and survival in jaundiced rats with endotoxin cholangitis. Lee CW, etal., World J Surg. 2006 Dec;30(12):2217-26. doi: 10.1007/s00268-006-0143-0.
22. Effect of compound IMMLG5521, a novel coumarin derivative, on carrageenan-induced pleurisy in rats. Li ZP, etal., Eur J Pharmacol. 2011 Jul 1;661(1-3):118-23. Epub 2011 Apr 27.
23. In mice, tuberculosis progression is associated with intensive inflammatory response and the accumulation of Gr-1 cells in the lungs. Lyadova IV, etal., PLoS One. 2010 May 4;5(5):e10469.
24. Low intensity laser therapy (LILT) in vivo acts on the neutrophils recruitment and chemokines/cytokines levels in a model of acute pulmonary inflammation induced by aerosol of lipopolysaccharide from Escherichia coli in rat. Mafra de Lima F, etal., J Photochem Photobiol B. 2010 Dec 2;101(3):271-8. Epub 2010 Jul 27.
25. CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Marcos V, etal., Nat Med. 2010 Sep;16(9):1018-23. Epub 2010 Sep 5.
26. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
27. MGDs mouse GO annotations MGD data from the GO Consortium
28. Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines. Miura TA, etal., Virology. 2007 Dec 20;369(2):288-98. Epub 2007 Sep 5.
29. Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis. Moser C, etal., APMIS. 2009 Feb;117(2):95-107.
30. Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat. Nanji AA, etal., Hepatology. 1999 Oct;30(4):934-43.
31. Mechanisms of acute inflammatory lung injury induced by abdominal sepsis. Neumann B, etal., Int Immunol. 1999 Feb;11(2):217-27.
32. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
33. Biomarkers of acute respiratory allergen exposure: screening for sensitization potential. Pucheu-Haston CM, etal., Toxicol Appl Pharmacol. 2010 Apr 15;244(2):144-55. Epub 2010 Jan 4.
34. Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. Raghavendran K, etal., J Surg Res. 2009 Aug;155(2):273-82. Epub 2008 Sep 16.
35. Preliminary investigation of a mice model of Klebsiella pneumoniae subsp. ozaenae induced pneumonia. Renois F, etal., Microbes Infect. 2011 Jun 30.
36. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
37. The temporal expression, cellular localization, and inhibition of the chemokines MIP-2 and MCP-1 after traumatic brain injury in the rat. Rhodes JK, etal., J Neurotrauma. 2009 Apr;26(4):507-25.
38. A rat model of picornavirus-induced airway infection and inflammation. Rosenthal LA, etal., Virol J. 2009 Aug 11;6:122.
39. Soot nanoparticles promote biotransformation, oxidative stress, and inflammation in murine lungs. Rouse RL, etal., Am J Respir Cell Mol Biol. 2008 Aug;39(2):198-207. Epub 2008 Mar 26.
40. The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia. Rovai LE, etal., J Leukoc Biol. 1998 Oct;64(4):494-502.
41. Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation. Sharma AK, etal., Respir Res. 2009 Jun 26;10:58.
42. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
43. Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Smith JB, etal., Immunogenetics 2002 Nov;54(8):599-603. Epub 2002 Oct 1.
44. Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. Su X, etal., Inflamm Res. 2011 Jul;60(7):619-32. Epub 2011 Feb 8.
45. Chemokine-dependent neutrophil recruitment in a murine model of Legionella pneumonia: potential role of neutrophils as immunoregulatory cells. Tateda K, etal., Infect Immun. 2001 Apr;69(4):2017-24.
46. The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury. Uchida Y, etal., Transplantation. 2010 May 15;89(9):1050-6.
47. Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. van den Berg E, etal., Am J Physiol Lung Cell Mol Physiol. 2011 Jul 8.
48. Elevated levels of macrophage inflammatory protein 2 in severe murine peritonitis increase neutrophil recruitment and mortality. Walley KR, etal., Infect Immun. 1997 Sep;65(9):3847-51.
49. Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent. Wu CL, etal., Shock. 2009 Sep;32(3):276-85.
50. Correlation of macrophage inflammatory protein-2 expression and brain edema in rats after intracerebral hemorrhage. Wu H, etal., Int J Clin Exp Pathol. 2009;2(1):83-90. Epub 2008 Jun 2.
51. [Effects of N-acetylcysteine on mRNA expression of monocyte chemotactic protein and macrophage inflammatory protein 2 in acute necrotizing pancreatitis: experiment with rats] Xu CF, etal., Zhonghua Yi Xue Za Zhi. 2008 Mar 11;88(10):711-5.
52. Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. Yang SJ, etal., Injury. 2011 Jul;42(7):638-42. Epub 2010 Aug 14.
53. Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza. Zavitz CC, etal., J Immunol. 2010 Feb 15;184(4):2001-13. Epub 2010 Jan 11.
54. A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. Zhao X, etal., J Surg Res. 2010 Aug;162(2):264-73. Epub 2009 Jun 6.
Additional References at PubMed
PMID:1402664   PMID:2201751   PMID:2643119   PMID:7961909   PMID:8496601   PMID:8759763   PMID:9622482   PMID:9730606   PMID:10349636   PMID:10394101   PMID:10570306   PMID:10714680  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11444905   PMID:11907123   PMID:12055258   PMID:12080938   PMID:12098066   PMID:12121220   PMID:12126650   PMID:12165537   PMID:12456657  
PMID:12466851   PMID:12477932   PMID:12604029   PMID:12759445   PMID:12807894   PMID:12875976   PMID:12957791   PMID:14583342   PMID:14673016   PMID:14704366   PMID:14761936   PMID:14978105  
PMID:15167973   PMID:15555540   PMID:15608143   PMID:15611273   PMID:15614130   PMID:15616592   PMID:15723811   PMID:15829306   PMID:15845480   PMID:16141072   PMID:16141073   PMID:16239543  
PMID:16521212   PMID:16602821   PMID:16606665   PMID:16618742   PMID:16684516   PMID:16855064   PMID:16863907   PMID:16873893   PMID:16940143   PMID:16964312   PMID:17130903   PMID:17237432  
PMID:17436230   PMID:17460147   PMID:17494633   PMID:17556491   PMID:17561115   PMID:17662241   PMID:17670839   PMID:17908807   PMID:17928531   PMID:18191274   PMID:18287966   PMID:18322244  
PMID:18347102   PMID:18452653   PMID:18536720   PMID:18542050   PMID:18606667   PMID:18771438   PMID:18983454   PMID:19131211   PMID:19330623   PMID:19470246   PMID:19839009   PMID:19893623  
PMID:19912257   PMID:19932745   PMID:20007247   PMID:20042461   PMID:20234283   PMID:20357249   PMID:20477948   PMID:20593289   PMID:20671197   PMID:20840653   PMID:21148126   PMID:21267068  
PMID:21308776   PMID:21317384   PMID:21488868   PMID:21507677   PMID:21865055   PMID:21873635   PMID:22007074   PMID:22135382   PMID:22277947   PMID:22342618   PMID:22564028   PMID:22686371  
PMID:23234294   PMID:23393393   PMID:23433011   PMID:23438680   PMID:23645836   PMID:23657854   PMID:24333183   PMID:24632845   PMID:24650562   PMID:24659080   PMID:24782490   PMID:24920846  
PMID:25084278   PMID:25093679   PMID:25114117   PMID:25184228   PMID:25349202   PMID:25445193   PMID:25545116   PMID:25603464   PMID:25762737   PMID:25907560   PMID:26163511   PMID:26311113  
PMID:26743624   PMID:26747783   PMID:27189410   PMID:27193261   PMID:27241286   PMID:27883091   PMID:27995997   PMID:28053238   PMID:28096401   PMID:28522730   PMID:28662496   PMID:28739876  
PMID:28765918   PMID:28928065   PMID:29509905   PMID:30201769   PMID:30248108   PMID:30251149   PMID:30323351   PMID:30337411   PMID:30446388   PMID:31132747   PMID:31292171   PMID:31519887  
PMID:31562139   PMID:31712428   PMID:32230838   PMID:32640236   PMID:32881070   PMID:33076328   PMID:33412104   PMID:33895326   PMID:34171415   PMID:34195684   PMID:34507947   PMID:34607953  
PMID:34784411   PMID:34899755   PMID:34905516   PMID:35493520   PMID:35726058   PMID:36577281   PMID:36867134   PMID:38218976  


Genomics

Comparative Map Data
Cxcl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,051,758 - 91,053,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl591,051,730 - 91,053,797 (+)EnsemblGRCm39 Ensembl
GRCm38590,903,899 - 90,905,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,332,925 - 91,334,964 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,979,099 - 91,981,138 (+)NCBIMGSCv36mm8
Celera589,048,217 - 89,050,256 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
CXCL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38474,097,040 - 74,099,195 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl474,097,040 - 74,099,196 (-)EnsemblGRCh38hg38GRCh38
GRCh37474,962,757 - 74,964,912 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,181,616 - 75,183,861 (-)NCBINCBI36Build 36hg18NCBI36
Build 34475,327,790 - 75,329,927NCBI
Celera472,322,837 - 72,325,084 (-)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,773,657 - 70,775,906 (-)NCBIHuRef
CHM1_1474,998,593 - 75,000,838 (-)NCBICHM1_1
T2T-CHM13v2.0477,440,641 - 77,442,796 (-)NCBIT2T-CHM13v2.0
Cxcl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81417,465,210 - 17,467,255 (-)NCBIGRCr8
mRatBN7.21417,181,030 - 17,183,075 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,181,062 - 17,183,075 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,181,873 - 17,183,917 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,500,809 - 18,502,853 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,192,924 - 17,194,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01418,731,346 - 18,733,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,731,378 - 18,733,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,640,312 - 18,642,357 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,677,129 - 18,679,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11418,677,128 - 18,679,175 (-)NCBI
Celera1416,558,112 - 16,560,157 (-)NCBICelera
Cytogenetic Map14p22NCBI
LOC100974886
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2355,960,804 - 55,963,432 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1456,150,028 - 56,152,424 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0450,092,989 - 50,095,541 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1455,925,562 - 55,927,809 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl455,925,562 - 55,986,555 (+)Ensemblpanpan1.1panPan2
CXCL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl870,157,214 - 70,159,138 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1870,157,253 - 70,159,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2874,310,094 - 74,311,988 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Cxcl2
88 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:227
Count of miRNA genes:195
Interacting mature miRNAs:210
Transcripts:ENSMUST00000075433
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57531534898019803Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57717582397658215Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
12910816Ogrq2_moverall growth rate QTL 2 (mouse)57717582397658215Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse

Markers in Region
X53798  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,905,195 - 90,905,305UniSTSGRCm38
MGSCv37591,334,221 - 91,334,331UniSTSGRCm37
Celera589,049,513 - 89,049,623UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS
Whitehead/MRC_RH51115.44UniSTS
PMC151656P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,904,215 - 90,904,379UniSTSGRCm38
MGSCv37591,333,241 - 91,333,405UniSTSGRCm37
Celera589,048,533 - 89,048,697UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS
Cxcl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,904,359 - 90,905,295UniSTSGRCm38
Celera589,048,677 - 89,049,613UniSTS
Cytogenetic Map5E1UniSTS
cM Map544.78UniSTS
UniSTS:489101  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,903,925 - 90,905,575UniSTSGRCm38
MGSCv37591,332,951 - 91,334,601UniSTSGRCm37
Celera589,048,243 - 89,049,893UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000075433   ⟹   ENSMUSP00000074885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200681   ⟹   ENSMUSP00000144334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,730 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200919
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202317
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,052,220 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,904,361 (+)Ensembl
RefSeq Acc Id: NM_009140   ⟹   NP_033166
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39591,051,758 - 91,053,797 (+)NCBI
GRCm38590,903,899 - 90,905,938 (+)ENTREZGENE
MGSCv37591,332,925 - 91,334,964 (+)RGD
Celera589,048,217 - 89,050,256 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033166   ⟸   NM_009140
- Peptide Label: precursor
- UniProtKB: P10889 (UniProtKB/Swiss-Prot),   Q3U1J5 (UniProtKB/TrEMBL),   Q3U1L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000074885   ⟸   ENSMUST00000075433
RefSeq Acc Id: ENSMUSP00000144334   ⟸   ENSMUST00000200681
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P10889-F1-model_v2 AlphaFold P10889 1-100 view protein structure

Promoters
RGD ID:6887130
Promoter ID:EPDNEW_M7016
Type:multiple initiation site
Name:Cxcl2_1
Description:Mus musculus chemokine (C-X-C motif) ligand 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38590,903,873 - 90,903,933EPDNEW
RGD ID:6837317
Promoter ID:MM_KWN:42850
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:ENSMUST00000075433,   UC008YBN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36591,332,696 - 91,333,196 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1340094 AgrOrtholog
Ensembl Genes ENSMUSG00000058427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075433 ENTREZGENE
  ENSMUST00000075433.8 UniProtKB/Swiss-Prot
  ENSMUST00000200681.4 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chemokine_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CXC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXC_Chemokine_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20310 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1340094 ENTREZGENE
NCBI Gene 20310 ENTREZGENE
PANTHER C-X-C MOTIF CHEMOKINE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cxcl2 PhenoGen
PRINTS INTERLEUKIN8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMALLCYTKCXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SMALL_CYTOKINES_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CXCL2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U1J5 ENTREZGENE, UniProtKB/TrEMBL
  Q3U1L9 ENTREZGENE, UniProtKB/TrEMBL
  Q3UCP1_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Cxcl2  C-X-C motif chemokine ligand 2  Cxcl2  chemokine (C-X-C motif) ligand 2  Symbol and/or name change 5135510 APPROVED