Cxcl2 (chemokine (C-X-C motif) ligand 2) - Rat Genome Database

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Gene: Cxcl2 (chemokine (C-X-C motif) ligand 2) Mus musculus
Symbol: Cxcl2
Name: chemokine (C-X-C motif) ligand 2
RGD ID: 733118
Description: Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Involved in response to molecule of bacterial origin. Located in extracellular space. Is expressed in several structures, including alimentary system; embryo mesenchyme; floor plate; respiratory system; and skin. Orthologous to several human genes including CXCL3 (C-X-C motif chemokine ligand 3); PARTICIPATES IN NOD-like receptor signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid; (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid.
Type: protein-coding
Also known as: C-X-C motif chemokine 2; CINC; CINC-2a; Gr; Gro2; GROb; macrophage inflammatory protein 2; Mgsa; Mgsa-b; Mi; MIP; MIP-2; MIP-2a; Mip2; Scy; Scyb; Scyb2; small inducible cytokine subfamily, member 2
RGD Orthologs
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39591,051,758 - 91,053,797 (+)NCBIGRCm39mm39
GRCm39 Ensembl591,051,730 - 91,053,797 (+)Ensembl
GRCm38590,903,899 - 90,905,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,332,925 - 91,334,964 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,979,099 - 91,981,138 (+)NCBImm8
Celera589,048,217 - 89,050,256 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid  (EXP)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (EXP)
(E)-cinnamyl alcohol  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,3-benzothiazole-2-thiol  (EXP)
1,4-phenylenediamine  (EXP)
1,7-dimethylxanthine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
13,14-dihydro-15-ketoprostaglandin D2  (EXP)
15-acetyldeoxynivalenol  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (EXP,ISO)
2-naphthylamine  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-aminobenzamide  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methyladenine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitroquinoline N-oxide  (EXP)
5-fluorouracil  (EXP)
6alpha-methylprednisolone  (ISO)
acrolein  (EXP)
Actein  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin G1  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP)
alpha-hexylcinnamaldehyde  (EXP)
amiloride  (EXP)
amiodarone  (EXP)
amlexanox  (EXP)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
amphibole asbestos  (ISO)
ampicillin  (EXP)
andrographolide  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antirheumatic drug  (ISO)
argatroban  (EXP)
aripiprazole  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
asbestos  (EXP)
asperentin  (EXP)
azathioprine  (EXP)
azetidine  (EXP)
Bardoxolone methyl  (EXP)
benzalkonium chloride  (EXP)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (EXP)
beta-D-glucosamine  (ISO)
beta-eudesmol  (EXP)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP,ISO)
boron nitride  (ISO)
bortezomib  (EXP,ISO)
budesonide  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
calcitriol  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
carrageenan  (EXP,ISO)
chenodeoxycholic acid  (EXP)
chloroethene  (EXP)
chlorothalonil  (ISO)
cholesterol  (ISO)
choline  (EXP)
chondroitin sulfate  (ISO)
cinnamyl alcohol  (EXP)
ciprofloxacin  (EXP)
cirsilineol  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
citral  (EXP)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corosolic acid  (EXP)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dantrolene  (EXP)
decabromodiphenyl ether  (ISO)
Decursin  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
Diallyl sulfide  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (EXP)
diflorasone  (EXP)
dimercaprol  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
divanadium pentaoxide  (EXP)
dizocilpine maleate  (EXP)
dobutamine  (EXP)
domperidone  (EXP)
dopexamine  (EXP)
doxorubicin  (ISO)
edaravone  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
endosulfan  (ISO)
enflurane  (ISO)
ethanol  (EXP,ISO)
ethylene glycol dimethacrylate  (EXP)
excitatory amino acid agonist  (EXP)
ferroheme b  (EXP)
flavonoids  (ISO)
flucloxacillin  (EXP)
flutamide  (EXP)
fomepizole  (ISO)
fulvestrant  (EXP,ISO)
fumonisin B1  (ISO)
furan  (ISO)
Fusarenone X  (EXP)
gadolinium trichloride  (EXP,ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
geranial  (EXP)
glucose  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
graphene oxide  (EXP)
graphite  (ISO)
halothane  (EXP,ISO)
heme b  (EXP)
heparin  (ISO)
hexadecanoic acid  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (EXP,ISO)
ibuprofen  (EXP,ISO)
imidurea  (EXP)
indometacin  (EXP,ISO)
iron atom  (ISO)
iron trichloride  (ISO)
iron(0)  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
isoeugenol  (EXP)
isoflurane  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lipoxin A4  (EXP)
lithocholic acid  (EXP)
LY294002  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
manganese(II) sulfate  (ISO)
maslinic acid  (EXP)
mercaptopurine  (ISO)
mercury dichloride  (ISO)
metacetamol  (EXP)
metformin  (EXP)
methamphetamine  (ISO)
methimazole  (EXP,ISO)
methotrexate  (ISO)
methyl methacrylate  (EXP)
methyl salicylate  (EXP)
methylmercury chloride  (EXP,ISO)
metoclopramide  (EXP)
mifepristone  (EXP)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
naproxen  (ISO)
naringin  (EXP)
neocuproine  (EXP)
neoechinulin A  (EXP)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nitrofen  (ISO)
nitrogen dioxide  (EXP,ISO)
Nivalenol  (EXP)
nonivamide  (EXP)
o-anisidine  (ISO)
obeticholic acid  (EXP)
olaparib  (EXP)
oleanolic acid  (EXP)
oleic acid  (ISO)
oligopeptide  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parthenolide  (EXP)
pentanal  (ISO)
Pentoxifylline  (ISO)
peptidoglycan  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phalloidin  (EXP)
phenanthridone  (EXP)
phenobarbital  (ISO)
phenytoin  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
poly(I:C)  (ISO)
polymyxin B2  (ISO)
pravastatin  (EXP,ISO)
prednisolone  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
propan-2-ol  (EXP)
propanal  (ISO)
prostaglandin D2  (EXP)
prostaglandin E1  (EXP)
purine-6-thiol  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinomethionate  (ISO)
rac-lactic acid  (EXP,ISO)
ranitidine  (ISO)
reactive oxygen species  (ISO)
resolvin D1  (EXP)
resolvin D2  (EXP)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
ritonavir  (ISO)
Roridin A  (EXP)
rotenone  (ISO)
ryanodine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
salicylic acid  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (EXP)
selenium atom  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium dodecyl sulfate  (EXP)
sterigmatocystin  (EXP)
succimer  (EXP)
sumatriptan  (ISO)
tauro-beta-muricholic acid  (EXP)
taurocholic acid  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetradecane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
Tiron  (EXP)
titanium dioxide  (EXP,ISO)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (ISO)
trans-isoeugenol  (EXP)
trichostatin A  (ISO)
triclosan  (EXP)
trimellitic anhydride  (EXP)
Triptolide  (EXP)
troglitazone  (EXP,ISO)
tropisetron  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
undecane  (ISO)
ursodeoxycholic acid  (EXP)
ursolic acid  (EXP)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
vitamin D  (EXP)
wortmannin  (ISO)
XL147  (EXP)
zaragozic acid A  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc protoporphyrin  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
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2. Bauer CM, etal., PLoS One. 2010 Oct 12;5(10):e13251.
3. Blanco-Melo D, etal., Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
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7. Colletti LM, etal., Hepatology. 2000 Feb;31(2):435-45.
8. Ding Y, etal., Zhonghua Gan Zang Bing Za Zhi. 2008 Mar;16(3):215-9.
9. Fine JS, etal., Inflammation. 2003 Aug;27(4):161-74.
10. Fujita T, etal., Biochem Pharmacol. 2010 May 15;79(10):1496-505. Epub 2010 Jan 22.
11. Gauglitz GG, etal., Shock. 2008 Nov;30(5):503-7.
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17. Kilpatrick LE, etal., J Leukoc Biol. 2011 Jan;89(1):3-10. Epub 2010 Aug 19.
18. KuoLee R, etal., Microbes Infect. 2011 May;13(5):447-56. Epub 2011 Jan 26.
19. Lee BH, etal., J Korean Med Sci. 2009 Oct;24(5):775-81. Epub 2009 Sep 23.
20. Lee CW, etal., World J Surg. 2006 Dec;30(12):2217-26. doi: 10.1007/s00268-006-0143-0.
21. Li ZP, etal., Eur J Pharmacol. 2011 Jul 1;661(1-3):118-23. Epub 2011 Apr 27.
22. Lyadova IV, etal., PLoS One. 2010 May 4;5(5):e10469.
23. Mafra de Lima F, etal., J Photochem Photobiol B. 2010 Dec 2;101(3):271-8. Epub 2010 Jul 27.
24. Marcos V, etal., Nat Med. 2010 Sep;16(9):1018-23. Epub 2010 Sep 5.
25. MGD and Homologene mouse data transfer
26. MGD data from the GO Consortium
27. Miura TA, etal., Virology. 2007 Dec 20;369(2):288-98. Epub 2007 Sep 5.
28. Moser C, etal., APMIS. 2009 Feb;117(2):95-107.
29. Nanji AA, etal., Hepatology. 1999 Oct;30(4):934-43.
30. Neumann B, etal., Int Immunol. 1999 Feb;11(2):217-27.
31. Pipeline to import KEGG annotations from KEGG into RGD
32. Pucheu-Haston CM, etal., Toxicol Appl Pharmacol. 2010 Apr 15;244(2):144-55. Epub 2010 Jan 4.
33. Raghavendran K, etal., J Surg Res. 2009 Aug;155(2):273-82. Epub 2008 Sep 16.
34. Renois F, etal., Microbes Infect. 2011 Jun 30.
35. RGD automated import pipeline for gene-chemical interactions
36. Rhodes JK, etal., J Neurotrauma. 2009 Apr;26(4):507-25.
37. Rosenthal LA, etal., Virol J. 2009 Aug 11;6:122.
38. Rouse RL, etal., Am J Respir Cell Mol Biol. 2008 Aug;39(2):198-207. Epub 2008 Mar 26.
39. Rovai LE, etal., J Leukoc Biol. 1998 Oct;64(4):494-502.
40. Sharma AK, etal., Respir Res. 2009 Jun 26;10:58.
41. Smith JB, etal., Immunogenetics 2002 Nov;54(8):599-603. Epub 2002 Oct 1.
42. Su X, etal., Inflamm Res. 2011 Jul;60(7):619-32. Epub 2011 Feb 8.
43. Tateda K, etal., Infect Immun. 2001 Apr;69(4):2017-24.
44. Uchida Y, etal., Transplantation. 2010 May 15;89(9):1050-6.
45. van den Berg E, etal., Am J Physiol Lung Cell Mol Physiol. 2011 Jul 8.
46. Walley KR, etal., Infect Immun. 1997 Sep;65(9):3847-51.
47. Wu CL, etal., Shock. 2009 Sep;32(3):276-85.
48. Wu H, etal., Int J Clin Exp Pathol. 2009;2(1):83-90. Epub 2008 Jun 2.
49. Xu CF, etal., Zhonghua Yi Xue Za Zhi. 2008 Mar 11;88(10):711-5.
50. Yang SJ, etal., Injury. 2011 Jul;42(7):638-42. Epub 2010 Aug 14.
51. Zavitz CC, etal., J Immunol. 2010 Feb 15;184(4):2001-13. Epub 2010 Jan 11.
52. Zhao X, etal., J Surg Res. 2010 Aug;162(2):264-73. Epub 2009 Jun 6.
Additional References at PubMed
PMID:1402664   PMID:2201751   PMID:2643119   PMID:7961909   PMID:8496601   PMID:8759763   PMID:9622482   PMID:9730606   PMID:10349636   PMID:10394101   PMID:10570306   PMID:10714680  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11444905   PMID:11907123   PMID:12055258   PMID:12080938   PMID:12098066   PMID:12121220   PMID:12126650   PMID:12165537   PMID:12456657  
PMID:12466851   PMID:12477932   PMID:12604029   PMID:12759445   PMID:12807894   PMID:12875976   PMID:12957791   PMID:14583342   PMID:14673016   PMID:14704366   PMID:14761936   PMID:14978105  
PMID:15167973   PMID:15555540   PMID:15608143   PMID:15611273   PMID:15614130   PMID:15616592   PMID:15723811   PMID:15829306   PMID:15845480   PMID:16141072   PMID:16141073   PMID:16239543  
PMID:16521212   PMID:16602821   PMID:16606665   PMID:16618742   PMID:16684516   PMID:16855064   PMID:16863907   PMID:16873893   PMID:16940143   PMID:16964312   PMID:17130903   PMID:17237432  
PMID:17436230   PMID:17460147   PMID:17494633   PMID:17556491   PMID:17561115   PMID:17662241   PMID:17670839   PMID:17908807   PMID:17928531   PMID:18191274   PMID:18287966   PMID:18322244  
PMID:18347102   PMID:18452653   PMID:18536720   PMID:18542050   PMID:18606667   PMID:18771438   PMID:18983454   PMID:19131211   PMID:19330623   PMID:19470246   PMID:19839009   PMID:19893623  
PMID:19912257   PMID:19932745   PMID:20007247   PMID:20042461   PMID:20234283   PMID:20357249   PMID:20477948   PMID:20593289   PMID:20671197   PMID:20840653   PMID:21148126   PMID:21267068  
PMID:21308776   PMID:21317384   PMID:21488868   PMID:21507677   PMID:21865055   PMID:21873635   PMID:22007074   PMID:22135382   PMID:22277947   PMID:22342618   PMID:22564028   PMID:22686371  
PMID:23234294   PMID:23393393   PMID:23433011   PMID:23438680   PMID:23645836   PMID:23657854   PMID:24333183   PMID:24632845   PMID:24650562   PMID:24659080   PMID:24782490   PMID:24920846  
PMID:25084278   PMID:25093679   PMID:25114117   PMID:25184228   PMID:25349202   PMID:25445193   PMID:25545116   PMID:25603464   PMID:25762737   PMID:25907560   PMID:26163511   PMID:26311113  
PMID:26743624   PMID:26747783   PMID:27189410   PMID:27193261   PMID:27241286   PMID:27883091   PMID:27995997   PMID:28053238   PMID:28096401   PMID:28522730   PMID:28662496   PMID:28739876  
PMID:28765918   PMID:28928065   PMID:29509905   PMID:30201769   PMID:30248108   PMID:30251149   PMID:30323351   PMID:30337411   PMID:30446388   PMID:31132747   PMID:31292171   PMID:31519887  
PMID:31562139   PMID:31712428   PMID:32230838   PMID:32640236   PMID:32881070   PMID:33076328   PMID:34507947  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39591,051,758 - 91,053,797 (+)NCBIGRCm39mm39
GRCm39 Ensembl591,051,730 - 91,053,797 (+)Ensembl
GRCm38590,903,899 - 90,905,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,332,925 - 91,334,964 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,979,099 - 91,981,138 (+)NCBImm8
Celera589,048,217 - 89,050,256 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl474,097,040 - 74,099,196 (-)EnsemblGRCh38hg38GRCh38
GRCh38474,097,040 - 74,099,195 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37474,962,757 - 74,964,912 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,181,616 - 75,183,861 (-)NCBINCBI36hg18NCBI36
Build 34475,327,790 - 75,329,927NCBI
Celera472,322,837 - 72,325,084 (-)NCBI
Cytogenetic Map4q13.3NCBI
HuRef470,773,657 - 70,775,906 (-)NCBIHuRef
CHM1_1474,998,593 - 75,000,838 (-)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21417,181,030 - 17,183,075 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1417,181,062 - 17,183,075 (-)Ensembl
Rnor_6.01418,731,346 - 18,733,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,731,378 - 18,733,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,640,312 - 18,642,357 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,677,129 - 18,679,175 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11418,677,128 - 18,679,175 (-)NCBI
Celera1416,558,112 - 16,560,157 (-)NCBICelera
Cytogenetic Map14p22NCBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1455,925,562 - 55,927,809 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl455,925,562 - 55,986,555 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0450,092,989 - 50,095,541 (+)NCBIMhudiblu_PPA_v0panPan3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl870,054,888 - 70,159,145 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1870,157,253 - 70,159,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2874,310,094 - 74,311,988 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,905,195 - 90,905,305UniSTSGRCm38
MGSCv37591,334,221 - 91,334,331UniSTSGRCm37
Celera589,049,513 - 89,049,623UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,904,215 - 90,904,379UniSTSGRCm38
MGSCv37591,333,241 - 91,333,405UniSTSGRCm37
Celera589,048,533 - 89,048,697UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,904,359 - 90,905,295UniSTSGRCm38
Celera589,048,677 - 89,049,613UniSTS
Cytogenetic Map5E1UniSTS
cM Map544.78UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,903,925 - 90,905,575UniSTSGRCm38
MGSCv37591,332,951 - 91,334,601UniSTSGRCm37
Celera589,048,243 - 89,049,893UniSTS
Cytogenetic Map5E1UniSTS
cM Map551.0UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined31975890100630065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined31975890100630065Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537424144112317856Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552537120107173175Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552537120107173175Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555230992100307666Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55230992108614761Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55816984192169980Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55945495493455133Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55945495493455133Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55945495493455133Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55945495493455133Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56009823494098356Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56025521594255313Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6250272196502841Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56250272196502841Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56250272196502841Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56250272196502841Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563548099104239199Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56422703098227149Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566381814100381814Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566381814100381814Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572271017106271152Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57515468797871944Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576042404110042620Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576132927110133058Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576132927110133058Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576132927110133058Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576297205110297366Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576297205110297366Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576297205110297366Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576297205110297366Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57702797697510356Mouse
12910816Ogrq2_moverall growth rate QTL 2 (mouse)57702797697510356Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579391781113391927Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580701400114701400Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined580871790114871944Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582690609116690738Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582690609116690738Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587239005121239199Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587239005121239199Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587239005121239199Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587239005121239199Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587239005121239199Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589271017118725963Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589271017124100176Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590173096124173175Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590413140124413285Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590413140124413285Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:227
Count of miRNA genes:195
Interacting mature miRNAs:210
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000075433   ⟹   ENSMUSP00000074885
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200681   ⟹   ENSMUSP00000144334
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,730 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,871 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200919
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,053,797 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,905,938 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202317
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,051,732 - 91,052,220 (+)Ensembl
GRCm38.p6 Ensembl590,903,873 - 90,904,361 (+)Ensembl
RefSeq Acc Id: NM_009140   ⟹   NP_033166
Mouse AssemblyChrPosition (strand)Source
GRCm39591,051,758 - 91,053,797 (+)NCBI
GRCm38590,903,899 - 90,905,938 (+)ENTREZGENE
MGSCv37591,332,925 - 91,334,964 (+)RGD
Celera589,048,217 - 89,050,256 (+)RGD
Reference Sequences
RefSeq Acc Id: NP_033166   ⟸   NM_009140
- Peptide Label: precursor
- UniProtKB: P10889 (UniProtKB/Swiss-Prot),   Q3U1J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000074885   ⟸   ENSMUST00000075433
RefSeq Acc Id: ENSMUSP00000144334   ⟸   ENSMUST00000200681
Protein Domains

RGD ID:6887130
Promoter ID:EPDNEW_M7016
Type:multiple initiation site
Description:Mus musculus chemokine (C-X-C motif) ligand 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm38590,903,873 - 90,903,933EPDNEW
RGD ID:6837317
Promoter ID:MM_KWN:42850
SO ACC ID:SO:0000170
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:ENSMUST00000075433,   UC008YBN.1
Mouse AssemblyChrPosition (strand)Source
MGSCv36591,332,696 - 91,333,196 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1340094 AgrOrtholog
Ensembl Genes ENSMUSG00000058427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000074885 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144334 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075433 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000200681 UniProtKB/TrEMBL
InterPro Chemokine_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CXC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXC_Chemokine_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20310 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PANTHER PTHR10179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cxcl2 PhenoGen
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL