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Gene: Fbn2 (fibrillin 2) Mus musculus
Symbol: Fbn2
Name: fibrillin 2
Description: Predicted to have extracellular matrix structural constituent. Involved in several processes, including bone trabecula formation; positive regulation of ossification; and sequestering of TGFbeta in extracellular matrix. Localizes to microfibril. Is expressed in several structures, including connective tissue; embryo mesenchyme; genitourinary system; heart; and respiratory system. Used to study distal arthrogryposis. Human ortholog(s) of this gene implicated in congenital contractural arachnodactyly and scoliosis. Orthologous to human FBN2 (fibrillin 2); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC063774; Fib-2; fibrillin-2; KIAA4226; mKIAA4226; sne; sy; syndatyly ems
Homo sapiens (human) : FBN2 (fibrillin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbn2 (fibrillin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbn2 (fibrillin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FBN2 (fibrillin 2)
Canis lupus familiaris (dog) : FBN2 (fibrillin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbn2 (fibrillin 2)
Sus scrofa (pig) : FBN2 (fibrillin 2)
Chlorocebus sabaeus (African green monkey) : FBN2 (fibrillin 2)
Heterocephalus glaber (naked mole-rat) : Fbn2 (fibrillin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1858,008,623 - 58,210,487 (-)EnsemblGRCm38mm10GRCm38
GRCm381858,008,623 - 58,210,572 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371858,168,277 - 58,369,580 (-)NCBIGRCm37mm9NCBIm37
MGSCv361858,135,627 - 58,335,174 (-)NCBImm8
Celera1859,320,066 - 59,527,555 (-)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1832.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733429
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.