Egfr (epidermal growth factor receptor) - Rat Genome Database

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Gene: Egfr (epidermal growth factor receptor) Mus musculus
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Symbol: Egfr
Name: epidermal growth factor receptor
RGD ID: 10511
MGI Page MGI
Description: Enables epidermal growth factor binding activity; epidermal growth factor receptor activity; and transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including ERBB2-EGFR signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; and positive regulation of fibroblast proliferation. Acts upstream of or within several processes, including eyelid development in camera-type eye; hair follicle development; and salivary gland morphogenesis. Located in several cellular components, including basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Is active in plasma membrane. Is expressed in several structures, including brain; integumental system; jaw; limb; and sensory organ. Used to study Coronavirus infectious disease and aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; lung non-small cell carcinoma (multiple); pancreatic cancer; prostate cancer; and pulmonary tuberculosis. Orthologous to human EGFR (epidermal growth factor receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; Erb; Erbb; Err; Errb1; Errp; Wa; wa-2; wa2; Wa5; waved 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391116,700,153 - 16,868,158 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1116,702,203 - 16,868,158 (+)EnsemblGRCm39 Ensembl
GRCm381116,752,203 - 16,913,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1116,752,203 - 16,918,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv371116,652,206 - 16,813,910 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361116,652,206 - 16,813,909 (+)NCBIMGSCv36mm8
Celera1117,126,474 - 17,287,898 (+)NCBICelera
Cytogenetic Map11A2NCBI
cM Map119.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Lung Injury  (IMP)
adenocarcinoma  (ISO)
adrenocortical carcinoma  (ISO)
Alcoholic Liver Diseases  (IMP)
Alzheimer's disease  (IMP)
Animal Mammary Neoplasms  (ISO)
aortic valve disease  (IAGP)
aortic valve stenosis  (IMP)
arteriovenous malformations of the brain  (ISO)
asthma  (IEP,IMP,ISO)
autistic disorder  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
Bannayan-Riley-Ruvalcaba syndrome  (ISO)
Bile Duct Neoplasms  (ISO)
Brain Neoplasms  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (IEP,ISO)
bronchiolo-alveolar adenocarcinoma  (IMP,ISO)
carcinoma  (ISO)
Cardiomegaly  (IDA)
cerebral palsy  (ISO)
Chloracne  (ISO)
cholangiocarcinoma  (ISO)
chronic obstructive pulmonary disease  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Coronavirus infectious disease  (IAGP)
Craniofacial Abnormalities  (ISO)
dementia  (ISO)
dermatitis  (ISO)
diabetes mellitus  (ISO)
diabetic retinopathy  (IMP,ISO)
dilated cardiomyopathy  (ISO)
Disease Progression  (ISO)
endometrial carcinoma  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
esophageal carcinoma  (ISO)
Esophageal Neoplasms  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
familial adenomatous polyposis  (ISO)
Gallbladder Neoplasms  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
head and neck cancer  (ISO)
Head and Neck Neoplasms  (ISO)
head and neck squamous cell carcinoma  (ISO)
Helicobacter Infections  (IMP,ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
high grade glioma  (ISO)
Huntington's disease  (IEP)
Hyperplasia  (ISO)
hypertension  (ISO)
Immediate Hypersensitivity  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Laryngeal Neoplasms  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (ISO)
leiomyoma  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (IMP)
malignant mesothelioma  (ISO)
median neuropathy  (ISO)
Mesothelioma  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neonatal Inflammatory Skin and Bowel Disease 2  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplasm Recurrence, Local  (ISO)
obesity  (IEP)
oral squamous cell carcinoma  (ISO)
osteosarcoma  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
papilloma  (IMP,ISO)
papillomavirus infectious disease  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
peptic esophagitis  (ISO)
Phyllodes Tumor  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary fibrosis  (IMP,ISO)
pulmonary hypertension  (IMP,ISO)
Pulmonary Hypertension, Hypoxia-Induced  (ISO)
pulmonary tuberculosis  (ISO)
rectal benign neoplasm  (ISO)
renal cell carcinoma  (ISO)
Right Ventricular Hypertrophy  (ISO)
schizophrenia  (ISO)
severe acute respiratory syndrome  (IMP)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (IMP)
Stomach Neoplasms  (ISO)
Tobacco Use Disorder  (ISO)
tongue squamous cell carcinoma  (IMP)
transitional cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
Vascular Remodeling  (ISO)
Ventricular Fibrillation  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(1->4)-beta-D-glucan  (EXP)
(20R)-protopanaxadiol  (ISO)
(20S)-ginsenoside Rg3  (ISO)
(R)-noradrenaline  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2,3,4,7,8-Hexachlorodibenzofuran  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,2-naphthoquinone  (ISO)
1,4-benzoquinone  (ISO)
1,4-naphthoquinone  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
16,16-dimethylprostaglandin E2  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 17-glucosiduronic acid  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,5-hexanedione  (ISO)
2-acetamidofluorene  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-nitrotoluene  (EXP)
3',5'-cyclic AMP  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitrophenol  (EXP)
4-nitrotoluene  (EXP)
4-tert-Octylphenol  (ISO)
4-vinylcyclohexene dioxide  (EXP)
5,6alpha-epoxy-5alpha-cholestan-3beta-ol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-chrysenamine  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7-ketocholesterol  (ISO)
8-Br-cAMP  (ISO)
9,10-phenanthroquinone  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
acteoside  (ISO)
actinomycin D  (ISO)
afatinib  (ISO)
afimoxifene  (ISO)
AH23848  (ISO)
AICA ribonucleotide  (ISO)
aldosterone  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alpha-naphthoflavone  (ISO)
alpha-pinene  (ISO)
alprenolol  (ISO)
aluminium oxide  (ISO)
AM-251  (ISO)
amiodarone  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amosite asbestos  (ISO)
amphibole asbestos  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimonite  (ISO)
antirheumatic drug  (ISO)
ANTU  (ISO)
apocynin  (ISO)
arachidonic acid  (ISO)
arecoline  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic acid  (ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
astragaloside IV  (ISO)
atenolol  (ISO)
atorvastatin calcium  (EXP)
ATP  (ISO)
atrazine  (ISO)
atropine  (ISO)
avobenzone  (ISO)
bafilomycin A1  (ISO)
baicalein  (ISO)
baicalin  (ISO)
benzamide  (ISO)
benzamidine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP,ISO)
benzo[b]fluoranthene  (EXP,ISO)
benzoic acid  (EXP)
berberine  (ISO)
betulin  (ISO)
betulinic acid  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bosutinib  (EXP)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
butylated hydroxyanisole  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium silicate  (ISO)
calcium(0)  (ISO)
canertinib  (EXP,ISO)
cannabidiol  (ISO)
capsaicin  (EXP,ISO)
carbon nanotube  (EXP)
carvacrol  (ISO)
carvedilol  (ISO)
casticin  (EXP)
CEDRELONE  (ISO)
celastrol  (ISO)
celecoxib  (ISO)
chloroprene  (ISO)
chloroquine  (ISO)
chlorothalonil  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
choline  (EXP)
chromium(6+)  (EXP,ISO)
chrysin  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (EXP)
cimetidine  (EXP,ISO)
Cinobufagin  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (EXP,ISO)
Cryptotanshinone  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (EXP)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (EXP,ISO)
cytochalasin B  (ISO)
cytochalasin D  (ISO)
dacomitinib  (EXP)
daidzein  (ISO)
DDE  (ISO)
deguelin  (ISO)
dehydroepiandrosterone  (ISO)
delphinidin  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
Didecyldimethylammonium  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disodium selenite  (EXP)
dobutamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
epoxiconazole  (EXP,ISO)
equol  (ISO)
Erionite  (ISO)
erlotinib hydrochloride  (ISO)
estrone  (EXP)
ethanol  (EXP,ISO)
etoposide  (ISO)
eugenol  (EXP)
everolimus  (ISO)
Evodiamine  (EXP)
fenamidone  (EXP)
fenofibrate  (EXP)
ferric oxide  (EXP)
fisetin  (ISO)
fluoranthene  (EXP)
fluoxetine  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formononetin  (ISO)
fulvestrant  (ISO)
furan  (ISO)
galangin  (ISO)
galaxolide  (ISO)
gallic acid  (ISO)
gedunin  (ISO)
gefitinib  (EXP,ISO)
geldanamycin  (EXP,ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (EXP,ISO)
glycine betaine  (EXP)
glyphosate  (ISO)
Goe 6976  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
helioxanthin  (EXP)
heparin  (ISO)
herbicide  (ISO)
hexachlorobenzene  (EXP,ISO)
hexadecanoic acid  (ISO)
histamine  (ISO)
hyaluronic acid  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroxamic acid  (EXP)
hyperforin  (ISO)
hypochlorous acid  (ISO)
icariin  (ISO)
icariside II  (ISO)
ICI-164384  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
inulin  (EXP)
irbesartan  (ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoflavones  (ISO)
isoprenaline  (EXP,ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
JTE-013  (ISO)
ketoconazole  (ISO)
KN-93  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lansoprazole  (ISO)
lapatinib  (ISO)
lead diacetate  (ISO)
lead nitrate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
leukotriene C4  (EXP)
linalool  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (ISO)
lovastatin  (ISO)
luteolin  (ISO)
LY294002  (ISO)
Maduramicin  (ISO)
magnesium dichloride  (ISO)
Malabaricone C  (EXP)
manganese(II) chloride  (ISO)
melittin  (ISO)
menadione  (ISO)
mercury dichloride  (ISO)
metamizole sodium  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methoxychlor  (ISO)
Methylazoxymethanol acetate  (ISO)
methylmercury chloride  (ISO)
mevalonic acid  (ISO)
microcystin-LR  (ISO)
mifepristone  (ISO)
MK-2206  (ISO)
monosodium L-glutamate  (EXP,ISO)
myo-inositol hexakisphosphate  (ISO)
myricetin  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylcysteamine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-methylformamide  (EXP)
N-methylnicotinate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naringin  (ISO)
nefazodone  (ISO)
neocuproine  (ISO)
neratinib  (ISO)
nevirapine  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP)
niclosamide  (ISO)
nicotine  (ISO)
nobiletin  (ISO)
O-methyleugenol  (EXP)
ochratoxin A  (EXP)
oleic acid  (ISO)
omipalisib  (ISO)
oridonin  (ISO)
osimertinib  (EXP,ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
oxazepam  (EXP)
oxytocin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
Paeonol  (ISO)
pamidronate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
paroxetine  (EXP)
PD 168393  (ISO)
pentane-2,3-dione  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
PHA-665752  (ISO)
phenobarbital  (EXP,ISO)
phenylarsine oxide  (EXP)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (EXP)
phosphoramidon  (ISO)
Phytolaccoside E  (ISO)
piperonyl butoxide  (EXP)
pirfenidone  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
platycodin D  (ISO)
ponatinib  (ISO)
potassium chromate  (ISO)
primaquine  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
propofol  (ISO)
propranolol  (ISO)
prostaglandin E2  (ISO)
protein kinase inhibitor  (ISO)
protoporphyrin  (ISO)
Ptaquiloside  (EXP)
pterostilbene  (ISO)
pyocyanine  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinazolines  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ranitidine  (ISO)
reactive oxygen species  (EXP,ISO)
resveratrol  (EXP,ISO)
romidepsin  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
ruthenium atom  (ISO)
rutin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
scopolamine  (ISO)
selenium atom  (ISO)
selenomethionine  (ISO)
senecionine  (EXP)
sepantronium  (ISO)
serpentine asbestos  (EXP,ISO)
sertraline  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium fluoride  (EXP)
sodium hydroxide  (ISO)
sorafenib  (ISO)
sotorasib  (ISO)
sphingosine 1-phosphate  (ISO)
staurosporine  (ISO)
stilbenoid  (ISO)
streptozocin  (ISO)
SU6656  (EXP,ISO)
succimer  (ISO)
sulfadimethoxine  (ISO)
sulfasalazine  (EXP,ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
Sulpyrine  (ISO)
sunitinib  (ISO)
suramin  (ISO)
taiwanin C  (EXP)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
taurocholic acid  (ISO)
tephrosin  (ISO)
Terfenadine  (ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
tetramethylpyrazine  (EXP)
tetraphene  (EXP)
tetrathiomolybdate(2-)  (ISO)
thapsigargin  (EXP)
theaflavin  (EXP)
thioacetamide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP,ISO)
torin 1  (ISO)
trans-piceid  (ISO)
triamterene  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
trovafloxacin  (EXP)
Tubeimoside II  (ISO)
tyrphostin AG 1478  (EXP,ISO)
U-73122  (ISO)
urethane  (EXP,ISO)
ursodeoxycholic acid  (ISO)
ursolic acid  (EXP)
UTP  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vandetanib  (ISO)
veliparib  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WIN 55212-2  (ISO)
wortmannin  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (ISO)
cell morphogenesis  (IGI)
cell population proliferation  (IGI)
cell surface receptor protein tyrosine kinase signaling pathway  (IBA)
cell surface receptor signaling pathway  (ISO)
cell-cell adhesion  (ISO)
cellular response to amino acid stimulus  (IDA)
cellular response to cadmium ion  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to growth factor stimulus  (IDA,ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to reactive oxygen species  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex cell migration  (IMP)
circadian rhythm  (ISO)
digestive tract morphogenesis  (IMP)
diterpenoid metabolic process  (ISO)
embryonic placenta development  (IMP)
epidermal growth factor receptor signaling pathway  (IDA,IGI,IMP,ISO)
epidermis development  (IMP)
epithelial cell proliferation  (IMP)
ERBB2-EGFR signaling pathway  (IDA,IMP,ISO)
eyelid development in camera-type eye  (IGI)
hair follicle development  (IGI,IMP,ISO)
hydrogen peroxide metabolic process  (ISO)
intracellular signal transduction  (ISO)
learning or memory  (ISO)
liver development  (ISO)
liver regeneration  (ISO)
lung development  (ISO)
midgut development  (ISO)
morphogenesis of an epithelial fold  (IMP)
negative regulation of apoptotic process  (IBA,ISO)
negative regulation of cardiocyte differentiation  (ISO)
negative regulation of epidermal growth factor receptor signaling pathway  (IDA,IMP,ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of protein catabolic process  (ISO)
neurogenesis  (IBA)
neuron projection morphogenesis  (ISO)
ovulation cycle  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of bone resorption  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (IDA,IGI,ISO)
positive regulation of DNA repair  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of epithelial cell proliferation  (IBA,IMP,ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fibroblast proliferation  (IMP)
positive regulation of G1/S transition of mitotic cell cycle  (ISO)
positive regulation of glial cell proliferation  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of mucus secretion  (ISO)
positive regulation of non-canonical NF-kappaB signal transduction  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of phosphorylation  (ISO)
positive regulation of prolactin secretion  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of superoxide anion generation  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of vasoconstriction  (ISO)
protein autophosphorylation  (ISO)
receptor-mediated endocytosis  (ISO)
regulation of cell population proliferation  (IGI)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of JNK cascade  (ISO)
regulation of peptidyl-tyrosine phosphorylation  (IMP,ISO)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
response to calcium ion  (ISO)
response to cobalamin  (ISO)
response to estradiol  (ISO)
response to hydroxyisoflavone  (ISO)
response to lipid  (ISO)
response to organic cyclic compound  (ISO)
response to oxidative stress  (ISO)
response to UV-A  (ISO)
salivary gland morphogenesis  (IMP)
signal transduction  (IDA,ISO)
tongue development  (ISO)
translation  (ISO)
vasodilation  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta morphology  (IAGP)
abnormal aortic valve morphology  (IAGP)
abnormal branching involved in lung morphogenesis  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal bronchiole epithelium morphology  (IAGP)
abnormal bronchus morphology  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal ciliary body morphology  (IAGP)
abnormal coat appearance  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal colon morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal epidermis stratum granulosum morphology  (IAGP)
abnormal esophageal epithelium morphology  (IAGP)
abnormal exocrine pancreas morphology  (IAGP)
abnormal eye anterior chamber morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal eyelid development  (IAGP)
abnormal eyelid morphology  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal filiform papillae morphology  (IAGP)
abnormal fungiform papillae morphology  (IAGP)
abnormal hair cortex keratinization  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal hair follicle inner root sheath morphology  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair follicle orientation  (IAGP)
abnormal hair growth  (IAGP)
abnormal hair medulla  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal hair texture  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart valve physiology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal inner cell mass morphology  (IAGP)
abnormal intestinal absorption  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal lactation  (IAGP)
abnormal lens fiber morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung interstitium morphology  (IAGP)
abnormal mammary gland morphology  (IAGP)
abnormal maternal decidual layer morphology  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal nail morphology  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreatic beta cell morphology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal pulmonary acinus morphology  (IAGP)
abnormal pulmonary alveolus epithelium morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal pulmonary interalveolar septum morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal semilunar valve morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal skin appearance  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin morphology  (IAGP)
abnormal skin pigmentation  (IAGP)
abnormal spongiotrophoblast layer morphology  (IAGP)
abnormal submandibular gland branching morphogenesis  (IAGP)
abnormal terminal bronchiole morphology  (IAGP)
abnormal tongue epithelium morphology  (IAGP)
abnormal tongue morphology  (IAGP)
abnormal trophoblast layer morphology  (IAGP)
abnormal type II pneumocyte morphology  (IAGP)
abnormal vagina orifice morphology  (IAGP)
abnormal vibrissa morphology  (IAGP)
absent eyelids  (IAGP)
absent vibrissae  (IAGP)
alopecia  (IAGP)
anterior iris synechia  (IAGP)
aortic valve regurgitation  (IAGP)
aortic valve stenosis  (IAGP)
asymmetric snout  (IAGP)
atelectasis  (IAGP)
cachexia  (IAGP)
calcified aortic valve  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
cataract  (IEA)
cleft palate  (IAGP)
congestive heart failure  (IAGP)
corneal opacity  (IAGP)
corneal scarring  (IAGP)
corneal vascularization  (IAGP)
curly vibrissae  (IAGP)
cyanosis  (IAGP)
decreased alveolar lamellar body number  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased brain size  (IAGP)
decreased cornea thickness  (IAGP)
decreased embryo size  (IAGP)
decreased embryo weight  (IAGP)
decreased fetal size  (IAGP)
decreased fibroblast cell migration  (IAGP)
decreased hair follicle number  (IAGP)
decreased leukocyte cell number  (IEA)
decreased Purkinje cell number  (IAGP)
decreased spongiotrophoblast size  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased survivor rate  (IAGP)
decreased trophoblast giant cell number  (IAGP)
decreased tumor growth/size  (IAGP)
decreased tumor incidence  (IAGP)
decreased ventricle muscle contractility  (IAGP)
dehydration  (IAGP)
delayed hair appearance  (IAGP)
delayed liver regeneration  (IAGP)
dermatitis  (IAGP)
dilated kidney collecting duct  (IAGP)
dilated respiratory conducting tube  (IAGP)
dilated terminal bronchiole tube  (IAGP)
disheveled coat  (IEA)
disorganized pancreatic islets  (IAGP)
distorted hair follicle pattern  (IAGP)
dry skin  (IAGP)
embryonic lethality at implantation, complete penetrance  (IAGP)
embryonic lethality between implantation and somite formation, incomplete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IEA)
enhanced osteoblast differentiation  (IAGP)
enlarged aortic valve  (IAGP)
enlarged semilunar valve  (IAGP)
epidermal atrophy  (IAGP)
eyelids open at birth  (IAGP)
failure of eyelid fusion  (IAGP)
flaky skin  (IAGP)
fused cornea and lens  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hematoma  (IAGP)
impaired lung alveolus development  (IAGP)
impaired skin barrier function  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased cardiac stroke volume  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased cornea thickness  (IAGP)
increased curvature of guard hairs  (IEA)
increased curvature of hairs  (IAGP)
increased foot pad pigmentation  (IAGP)
increased heart left ventricle size  (IAGP)
increased heart rate  (IAGP)
increased IgE level  (IAGP)
increased left ventricle diastolic pressure  (IAGP)
increased left ventricle systolic pressure  (IAGP)
increased pulse pressure  (IAGP)
increased skin papilloma incidence  (IAGP)
increased skin tumor incidence  (IAGP)
increased susceptibility to Coronaviridae infection  (IAGP)
increased susceptibility to Coronaviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased systemic arterial blood pressure  (IAGP)
increased T-helper 1 cell number  (IAGP)
increased T-helper 17 cell number  (IAGP)
increased T-helper 2 cell number  (IAGP)
increased tumor growth/size  (IAGP)
intestinal hypoperistalsis  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
long snout  (IAGP)
long toenails  (IAGP)
loss of vibrissae  (IAGP)
mandible hypoplasia  (IAGP)
microphthalmia  (IAGP)
myocardium hypertrophy  (IAGP)
narrow snout  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
petechiae  (IAGP)
placental labyrinth hypoplasia  (IAGP)
plush coat  (IAGP)
pointed snout  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature chondrocyte differentiation  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
prolonged PR interval  (IAGP)
prolonged QRS complex duration  (IAGP)
prolonged QT interval  (IAGP)
prolonged RR interval  (IAGP)
prolonged ST segment  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
rough coat  (IEA)
short hair  (IAGP)
short mandible  (IAGP)
short vibrissae  (IEA)
slow postnatal weight gain  (IAGP)
small cerebellum  (IAGP)
small lens  (IAGP)
small mandible  (IAGP)
small Meckel's cartilage  (IAGP)
small pancreas  (IAGP)
small placenta  (IAGP)
sparse hair  (IAGP)
thick aortic valve  (IAGP)
thick epidermis  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
thick pulmonary valve  (IAGP)
thick skin  (IEA)
thin cerebral cortex  (IAGP)
thin epidermis  (IAGP)
thin skin  (IAGP)
vacuolated lens  (IAGP)
waved hair  (IAGP)
wavy vibrissae  (IAGP)
weight loss  (IAGP)
References

References - curated
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PMID:23440919   PMID:23457600   PMID:23472148   PMID:23526992   PMID:23563729   PMID:23603262   PMID:23606057   PMID:23638043   PMID:23652202   PMID:23652203   PMID:23657465   PMID:23681474  
PMID:23684791   PMID:23695674   PMID:23698748   PMID:23706492   PMID:23787120   PMID:23799367   PMID:23813870   PMID:23842642   PMID:23872073   PMID:23894460   PMID:23899604   PMID:23913923  
PMID:23918928   PMID:23928863   PMID:23929714   PMID:23948867   PMID:23966299   PMID:23966300   PMID:23968914   PMID:24015256   PMID:24043629   PMID:24047696   PMID:24047892   PMID:24079739  
PMID:24129405   PMID:24142862   PMID:24154525   PMID:24155954   PMID:24161570   PMID:24198336   PMID:24240174   PMID:24247599   PMID:24253040   PMID:24255704   PMID:24270888   PMID:24283698  
PMID:24337738   PMID:24371813   PMID:24390343   PMID:24391216   PMID:24407590   PMID:24493201   PMID:24496615   PMID:24530706   PMID:24550287   PMID:24552586   PMID:24561579   PMID:24607897  
PMID:24695557   PMID:24697349   PMID:24740605   PMID:24768699   PMID:24771701   PMID:24891618   PMID:24895124   PMID:24945252   PMID:24945379   PMID:24952961   PMID:25032849   PMID:25083990  
PMID:25089660   PMID:25138052   PMID:25173978   PMID:25185988   PMID:25186737   PMID:25202019   PMID:25210793   PMID:25217659   PMID:25222135   PMID:25223639   PMID:25278152   PMID:25305142  
PMID:25327963   PMID:25330173   PMID:25334070   PMID:25375038   PMID:25375133   PMID:25377219   PMID:25382637   PMID:25385589   PMID:25414100   PMID:25420773   PMID:25448158   PMID:25451232  
PMID:25455687   PMID:25497016   PMID:25503263   PMID:25521828   PMID:25531554   PMID:25546423   PMID:25572823   PMID:25615642   PMID:25623042   PMID:25631042   PMID:25733240   PMID:25735773  
PMID:25738454   PMID:25738567   PMID:25744720   PMID:25808866   PMID:25818318   PMID:25899687   PMID:25902485   PMID:25912735   PMID:25915403   PMID:25918388   PMID:25969993   PMID:25985273  
PMID:25985800   PMID:25997932   PMID:26027747   PMID:26036345   PMID:26055326   PMID:26068590   PMID:26109068   PMID:26115514   PMID:26120493   PMID:26176759   PMID:26204818   PMID:26243875  
PMID:26247735   PMID:26272609   PMID:26338334   PMID:26341626   PMID:26341921   PMID:26370283   PMID:26411367   PMID:26438881   PMID:26455392   PMID:26483551   PMID:26486084   PMID:26492470  
PMID:26492920   PMID:26592448   PMID:26633882   PMID:26653334   PMID:26661905   PMID:26724533   PMID:26745185   PMID:26764350   PMID:26789017   PMID:26916220   PMID:26918608   PMID:26930157  
PMID:27012600   PMID:27077118   PMID:27105606   PMID:27110918   PMID:27113764   PMID:27146149   PMID:27152417   PMID:27158778   PMID:27165742   PMID:27251290   PMID:27267807   PMID:27273304  
PMID:27306184   PMID:27317889   PMID:27330189   PMID:27346347   PMID:27401248   PMID:27447178   PMID:27449755   PMID:27475257   PMID:27477273   PMID:27482886   PMID:27502168   PMID:27507810  
PMID:27549668   PMID:27586651   PMID:27587395   PMID:27601049   PMID:27626655   PMID:27641601   PMID:27650496   PMID:27719760   PMID:27738329   PMID:27760309   PMID:27775074   PMID:27881077  
PMID:27911782   PMID:27965054   PMID:27991932   PMID:28004780   PMID:28057438   PMID:28085498   PMID:28166195   PMID:28232522   PMID:28263971   PMID:28343910   PMID:28356285   PMID:28374780  
PMID:28378742   PMID:28418591   PMID:28424251   PMID:28425446   PMID:28472347   PMID:28472654   PMID:28494873   PMID:28542142   PMID:28564633   PMID:28611210   PMID:28626027   PMID:28646091  
PMID:28656962   PMID:28703301   PMID:28759045   PMID:28783046   PMID:28790147   PMID:28818950   PMID:28831150   PMID:28885660   PMID:28933590   PMID:28978917   PMID:29024567   PMID:29028997  
PMID:29044125   PMID:29045902   PMID:29051215   PMID:29058721   PMID:29093447   PMID:29152859   PMID:29160908   PMID:29191921   PMID:29238610   PMID:29336487   PMID:29415171   PMID:29427771  
PMID:29438224   PMID:29445126   PMID:29459677   PMID:29472497   PMID:29473311   PMID:29483644   PMID:29531172   PMID:29672156   PMID:29700307   PMID:29894692   PMID:29898872   PMID:29959129  
PMID:29992578   PMID:30028091   PMID:30072422   PMID:30157281   PMID:30188763   PMID:30219864   PMID:30352854   PMID:30354220   PMID:30361264   PMID:30515795   PMID:30521373   PMID:30550785  
PMID:30578323   PMID:30590030   PMID:30637799   PMID:30644388   PMID:30679495   PMID:30705084   PMID:30713094   PMID:30735525   PMID:30770250   PMID:30956133   PMID:30973865   PMID:30975481  
PMID:30979723   PMID:31042082   PMID:31122699   PMID:31131063   PMID:31138677   PMID:31217524   PMID:31251840   PMID:31290228   PMID:31292196   PMID:31298955   PMID:31425777   PMID:31426531  
PMID:31562318   PMID:31562860   PMID:31671073   PMID:31722218   PMID:31732166   PMID:31805013   PMID:31826981   PMID:31931029   PMID:31964750   PMID:32045617   PMID:32046347   PMID:32096290  
PMID:32150794   PMID:32161758   PMID:32179676   PMID:32188578   PMID:32251323   PMID:32253238   PMID:32316750   PMID:32325033   PMID:32335999   PMID:32369572   PMID:32416134   PMID:32422931  
PMID:32447809   PMID:32499177   PMID:32538139   PMID:32548701   PMID:32558183   PMID:32561725   PMID:32601248   PMID:32700456   PMID:32727536   PMID:32747435   PMID:32875609   PMID:32888953  
PMID:32926474   PMID:32931498   PMID:32943616   PMID:33053360   PMID:33094683   PMID:33141023   PMID:33153107   PMID:33181234   PMID:33202981   PMID:33322301   PMID:33373325   PMID:33500443  
PMID:33561544   PMID:33572344   PMID:33762435   PMID:33767440   PMID:33790318   PMID:33795534   PMID:33826887   PMID:33892492   PMID:33989815   PMID:34060720   PMID:34075041   PMID:34168192  
PMID:34193412   PMID:34228904   PMID:34239035   PMID:34320238   PMID:34321999   PMID:34459138   PMID:34520454   PMID:34675506   PMID:34714866   PMID:34725466   PMID:34772946   PMID:34773433  
PMID:34843459   PMID:34843542   PMID:34916513   PMID:34963132   PMID:34997943   PMID:35013230   PMID:35132961   PMID:35149991   PMID:35191092   PMID:35298048   PMID:35388219   PMID:35618635  
PMID:35685988   PMID:35741065   PMID:35948530   PMID:35972910   PMID:36044040   PMID:36142585   PMID:36396012   PMID:36429119   PMID:36445254   PMID:36460130   PMID:36581018   PMID:36657561  
PMID:36718792   PMID:36764291   PMID:36853175   PMID:36915679   PMID:36946774   PMID:37094666   PMID:37119853   PMID:37154060   PMID:37165726   PMID:37171232   PMID:37268107   PMID:37341059  
PMID:37656314   PMID:37666482   PMID:37728308   PMID:37795611   PMID:37858681   PMID:37903947   PMID:37963889   PMID:38003472   PMID:38037126   PMID:38237399  


Genomics

Comparative Map Data
Egfr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391116,700,153 - 16,868,158 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1116,702,203 - 16,868,158 (+)EnsemblGRCm39 Ensembl
GRCm381116,752,203 - 16,913,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1116,752,203 - 16,918,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv371116,652,206 - 16,813,910 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361116,652,206 - 16,813,909 (+)NCBIMGSCv36mm8
Celera1117,126,474 - 17,287,898 (+)NCBICelera
Cytogenetic Map11A2NCBI
cM Map119.41NCBI
EGFR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38755,019,017 - 55,211,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl755,019,017 - 55,211,628 (+)EnsemblGRCh38hg38GRCh38
GRCh37755,086,710 - 55,279,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36755,054,219 - 55,242,525 (+)NCBINCBI36Build 36hg18NCBI36
Build 34754,860,933 - 55,012,947NCBI
Celera755,192,332 - 55,380,657 (+)NCBICelera
Cytogenetic Map7p11.2NCBI
HuRef754,924,934 - 55,112,834 (+)NCBIHuRef
CHM1_1755,089,165 - 55,277,398 (+)NCBICHM1_1
T2T-CHM13v2.0755,178,937 - 55,372,056 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2755,092,507 - 55,280,831 (+)NCBI
Egfr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81495,378,626 - 95,551,358 (+)NCBIGRCr8
mRatBN7.21491,176,979 - 91,349,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1491,177,067 - 91,344,382 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1495,489,293 - 95,663,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01496,733,623 - 96,907,493 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01493,198,702 - 93,372,564 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01499,919,485 - 100,104,136 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1499,919,485 - 100,098,796 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014100,438,989 - 100,617,315 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41497,617,358 - 97,788,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1490,225,928 - 90,392,779 (+)NCBICelera
RH 3.4 Map14 RGD
Cytogenetic Map14q22NCBI
Egfr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955456321,222 - 456,431 (-)NCBIChiLan1.0ChiLan1.0
EGFR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2659,852,898 - 60,046,419 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17108,177,622 - 108,371,205 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0755,614,042 - 55,807,285 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1756,048,212 - 56,117,642 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl756,046,296 - 56,111,615 (+)Ensemblpanpan1.1panPan2
EGFR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1185,983,669 - 6,044,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha185,693,578 - 5,890,886 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0185,890,289 - 6,087,722 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl185,890,228 - 6,085,544 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1185,880,554 - 6,077,776 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0185,854,700 - 6,051,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0185,960,845 - 6,158,207 (+)NCBIUU_Cfam_GSD_1.0
Egfr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118109,328,850 - 109,524,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936678365,834 - 436,528 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936678365,005 - 560,546 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGFR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9139,300,022 - 139,475,589 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19139,302,410 - 139,474,632 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EGFR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,664,622 - 3,853,492 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,666,339 - 3,853,239 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606218,644,141 - 18,836,149 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Egfr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624740589,606 - 713,271 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624740584,133 - 713,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Egfr
5807 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2694
Count of miRNA genes:889
Interacting mature miRNAs:1280
Transcripts:ENSMUST00000020329, ENSMUST00000102884, ENSMUST00000125984, ENSMUST00000138518, ENSMUST00000139722
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226794Feml9_mfemur length 9, 5 week (mouse)11705000016750000Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse

Markers in Region
AI552599  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381116,917,973 - 16,918,107UniSTSGRCm38
MGSCv371116,817,976 - 16,818,110UniSTSGRCm37
Celera1117,291,928 - 17,292,062UniSTS
Cytogenetic Map11A1-A4UniSTS
Whitehead/MRC_RH11151.53UniSTS
X78987  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381116,911,992 - 16,912,152UniSTSGRCm38
MGSCv371116,811,995 - 16,812,155UniSTSGRCm37
Celera1117,285,983 - 17,286,143UniSTS
Cytogenetic Map11A1-A4UniSTS
Whitehead/MRC_RH11155.08UniSTS
Whitehead_YAC11 UniSTS
PMC122223P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381116,896,819 - 16,897,001UniSTSGRCm38
MGSCv371116,796,822 - 16,797,004UniSTSGRCm37
Celera1117,270,752 - 17,270,934UniSTS
Cytogenetic Map11A1-A4UniSTS
Egfr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1-A4UniSTS
cM Map119.0UniSTS
Egfr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1-A4UniSTS
Egfr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1-A4UniSTS
X78987  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381116,911,857 - 16,911,945UniSTSGRCm38
MGSCv371116,811,860 - 16,811,948UniSTSGRCm37
Celera1117,285,848 - 17,285,936UniSTS
Cytogenetic Map11A1-A4UniSTS
Whitehead/MRC_RH11155.08UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF124513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF125256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF275367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF277898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF456454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ553815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX255277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY725722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U03425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X59698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z12608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000020329   ⟹   ENSMUSP00000020329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1116,702,211 - 16,868,158 (+)Ensembl
GRCm38.p6 Ensembl1116,752,211 - 16,918,158 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102884   ⟹   ENSMUSP00000099948
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1116,702,203 - 16,837,923 (+)Ensembl
GRCm38.p6 Ensembl1116,752,203 - 16,887,923 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125984   ⟹   ENSMUSP00000122632
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1116,828,150 - 16,834,357 (+)Ensembl
GRCm38.p6 Ensembl1116,878,150 - 16,884,357 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138518
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1116,855,185 - 16,860,809 (+)Ensembl
GRCm38.p6 Ensembl1116,905,185 - 16,910,809 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1116,702,230 - 16,743,744 (+)Ensembl
GRCm38.p6 Ensembl1116,752,230 - 16,793,744 (+)Ensembl
RefSeq Acc Id: NM_007912   ⟹   NP_031938
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391116,702,203 - 16,837,658 (+)NCBI
GRCm381116,752,203 - 16,887,658 (+)NCBI
MGSCv371116,652,206 - 16,813,910 (+)RGD
Celera1117,126,474 - 17,287,898 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_207655   ⟹   NP_997538
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391116,702,203 - 16,863,907 (+)NCBI
GRCm381116,752,203 - 16,913,907 (+)ENTREZGENE
MGSCv371116,652,206 - 16,813,910 (+)RGD
Celera1117,126,474 - 17,287,898 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156288   ⟹   XP_036012181
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391116,700,153 - 16,868,158 (+)NCBI
Sequence:
RefSeq Acc Id: NP_997538   ⟸   NM_207655
- Peptide Label: isoform 1 precursor
- UniProtKB: Q01279 (UniProtKB/Swiss-Prot),   Q9EP98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_031938   ⟸   NM_007912
- Peptide Label: isoform 2 precursor
- UniProtKB: Q9WVF5 (UniProtKB/TrEMBL),   Q5SVE9 (UniProtKB/TrEMBL),   Q9ERV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000122632   ⟸   ENSMUST00000125984
RefSeq Acc Id: ENSMUSP00000020329   ⟸   ENSMUST00000020329
RefSeq Acc Id: ENSMUSP00000099948   ⟸   ENSMUST00000102884
RefSeq Acc Id: XP_036012181   ⟸   XM_036156288
- Peptide Label: isoform X1
- UniProtKB: Q9EP98 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01279-F1-model_v2 AlphaFold Q01279 1-1210 view protein structure

Promoters
RGD ID:6820760
Promoter ID:MM_KWN:6502
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000020325,   OTTMUST00000011585,   OTTMUST00000011586,   OTTMUST00000017964
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361116,651,994 - 16,652,494 (+)MPROMDB
RGD ID:8674008
Promoter ID:EPDNEW_M15035
Type:initiation region
Name:Egfr_1
Description:Mus musculus epidermal growth factor receptor , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381116,752,230 - 16,752,290EPDNEW
RGD ID:6820761
Promoter ID:MM_KWN:6504
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000011587
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361116,777,811 - 16,778,311 (+)MPROMDB
RGD ID:6820762
Promoter ID:MM_KWN:6505
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000011588,   UC007IBP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361116,804,211 - 16,805,162 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95294 AgrOrtholog
Ensembl Genes ENSMUSG00000020122 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020329 ENTREZGENE
  ENSMUST00000020329.13 UniProtKB/Swiss-Prot
  ENSMUST00000102884 ENTREZGENE
  ENSMUST00000102884.10 UniProtKB/TrEMBL
  ENSMUST00000125984.2 UniProtKB/TrEMBL
Gene3D-CATH 3.80.20.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.2930 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Egfr_JX_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Furin-like_Cys-rich_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Furin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rcpt_L-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rcpt_L-dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_EGF/ERB/XmrK_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13649 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95294 ENTREZGENE
NCBI Gene 13649 ENTREZGENE
PANTHER EPIDERMAL GROWTH FACTOR RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Furin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Recep_L_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB EGFR RGD
PhenoGen Egfr PhenoGen
PIRSF TyrPK_EGF-R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00261 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt EGFR_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TQS6_MOUSE UniProtKB/TrEMBL
  Q5SVE7_MOUSE UniProtKB/TrEMBL
  Q5SVE9 ENTREZGENE
  Q99PK1_MOUSE UniProtKB/TrEMBL
  Q9EP98 ENTREZGENE, UniProtKB/TrEMBL
  Q9ERV6 ENTREZGENE, UniProtKB/TrEMBL
  Q9WVF5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5SVE9 UniProtKB/TrEMBL