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Gene: Hgf (hepatocyte growth factor) Mus musculus
Symbol: Hgf
Name: hepatocyte growth factor
Description: Predicted to have several functions, including protein heterodimerization activity; receptor ligand activity; and serine-type endopeptidase activity. Involved in several processes, including negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; and regulation of protein phosphorylation. Predicted to localize to the extracellular space. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); and neuropathy (multiple). Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human HGF (hepatocyte growth factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C230052L06Rik; hepatopoeitin-A; hepatopoietin-A; HGF/SF; NK1; NK2; scatter factor; SF; SF/HGF
Homo sapiens (human) : HGF (hepatocyte growth factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hgf (hepatocyte growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hgf (hepatocyte growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : HGF (hepatocyte growth factor)
Canis lupus familiaris (dog) : HGF (hepatocyte growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hgf (hepatocyte growth factor)
Sus scrofa (pig) : HGF (hepatocyte growth factor)
Chlorocebus sabaeus (African green monkey) : HGF (hepatocyte growth factor)
Heterocephalus glaber (naked mole-rat) : Hgf (hepatocyte growth factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl516,553,495 - 16,620,152 (+)Ensembl
GRCm38516,553,495 - 16,619,439 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37516,059,368 - 16,125,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv36516,065,374 - 16,131,263 (+)NCBImm8
Celera513,551,947 - 13,617,800 (+)NCBICelera
Cytogenetic Map5 A3NCBI
cM Map57.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hgf
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10708
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.