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Gene: Fabp5 (fatty acid binding protein 5, epidermal) Mus musculus
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Symbol: Fabp5
Name: fatty acid binding protein 5, epidermal
Description: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. In humans this gene has been associated with psoriasis and type 2 diabetes. In mouse deficiency of this gene in combination with a deficiency in Fabp4 confers protection against atherosclerosis, diet-induced obesity, insulin resistance and experimental autoimmune encephalomyelitis (the mouse model for multiple sclerosis). Alternative splicing results in multiple transcript variants that encode different protein isoforms. The mouse genome contains many pseudogenes similar to this locus. [provided by RefSeq, Jan 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E-FABP; epidermal-type fatty acid-binding protein; epithelial fatty acid-binding protein; Fabpe; Fabpe E-FABP; fatty acid-binding protein 5; fatty acid-binding protein, epidermal; keratinocyte lipid binding protein; keratinocyte lipid-binding protein; Klbp; mal1; PA-FABP; psoriasis-associated fatty acid-binding protein homolog; putative Fabp5 product; uncharacterized protein LOC16592
Orthologs:
Homo sapiens (human) : FABP5 (fatty acid binding protein 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fabp5 (fatty acid binding protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fabp5 (fatty acid binding protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FABP5 (fatty acid binding protein 5)
Canis lupus familiaris (dog) : LOC102155424 (fatty acid-binding protein, epidermal)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fabp5 (fatty acid binding protein 5)
Sus scrofa (pig) : FABP5 (fatty acid binding protein 5)
more info ...
Related Pseudogenes: Fabp5l2   Gm13998   Gm14328   Gm6100   Gm6166  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38310,012,585 - 10,016,610 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37310,012,606 - 10,016,610 (+)NCBIGRCm37mm9NCBIm37
MGSCv3639,995,138 - 9,999,142 (+)NCBImm8
Celera310,036,262 - 10,040,303 (+)NCBICelera
Cytogenetic Map3 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fabp5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731966
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.