Igfbp3 (insulin-like growth factor binding protein 3) - Rat Genome Database

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Gene: Igfbp3 (insulin-like growth factor binding protein 3) Mus musculus
Analyze
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
RGD ID: 10774
MGI Page MGI
Description: Enables fibronectin binding activity and insulin-like growth factor binding activity. Acts upstream of or within several processes, including osteoblast differentiation; positive regulation of signal transduction; and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early embryo; gonad; and limb. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Turner syndrome; diabetes mellitus (multiple); prostate cancer; and transitional cell carcinoma. Orthologous to human IGFBP3 (insulin like growth factor binding protein 3); PARTICIPATES IN insulin-like growth factor signaling pathway; p53 signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI649005; IBP-3; IGF-binding protein 3; IGFBP; IGFBP-3; IGgfbp3; insulin-like growth factor-binding protein 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,156,086 - 7,165,498 (-)NCBIGRCm39mm39
GRCm39 Ensembl117,156,086 - 7,163,923 (-)Ensembl
GRCm38117,206,086 - 7,215,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,206,086 - 7,213,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv37117,106,089 - 7,113,926 (-)NCBIGRCm37mm9NCBIm37
MGSCv36117,108,384 - 7,113,834 (-)NCBImm8
Celera117,681,286 - 7,689,161 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
Acute-Phase Reaction  (ISO)
Alzheimer's disease  (IEP,ISO)
ankylosing spondylitis  (ISO)
arteriosclerosis  (ISO)
autistic disorder  (ISO)
Barrett's esophagus  (ISO)
beta thalassemia  (ISO)
breast cancer  (ISO)
Burns  (ISO)
cervix uteri carcinoma in situ  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Adrenal Hyperplasia due to 21 Hydroxylase Deficiency  (ISO)
congenital diaphragmatic hernia  (ISO)
congenital disorder of glycosylation Ia  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
cystic fibrosis  (ISO)
Down syndrome  (ISO)
Dwarfism  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
Endotoxemia  (ISO)
epidermolysis bullosa dystrophica  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
Experimental Liver Cirrhosis  (ISO)
Fetal Growth Retardation  (ISO)
Fetal Macrosomia  (ISO)
Head Injuries, Closed  (ISO)
high grade glioma  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
ichthyosis  (ISO)
impotence  (ISO)
inflammatory bowel disease  (ISO)
Insulin Resistance  (ISO)
Malocclusion  (ISO)
McCune Albright syndrome  (ISO)
Metabolic Bone Diseases  (ISO)
myeloid leukemia  (ISO)
Myocardial Ischemia  (ISO)
obesity  (ISO)
ornithine carbamoyltransferase deficiency  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
Ovarian Neoplasms  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
primary progressive multiple sclerosis  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary fibrosis  (ISO)
renal cell carcinoma  (ISO)
retinopathy of prematurity  (ISO)
rheumatoid arthritis  (ISO)
Spinal Fractures  (ISO)
Spontaneous Abortions  (ISO)
Stomach Neoplasms  (ISO)
systemic scleroderma  (ISO)
tonsillitis  (ISO)
transitional cell carcinoma  (ISO)
Turner syndrome  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(R)-lipoic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (ISO)
2-methylcholine  (ISO)
2-nitrofluorene  (ISO)
2-nitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,4-dichloroaniline  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aluminium sulfate (anhydrous)  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
azathioprine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromochloroacetic acid  (ISO)
bucladesine  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calciol  (EXP)
calcitriol  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
chlorohydrocarbon  (ISO)
chloroprene  (EXP)
cholesterol  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
dehydroepiandrosterone  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP,ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
fonofos  (ISO)
fructose  (ISO)
gadolinium trichloride  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
glafenine  (ISO)
glutathione  (EXP)
glycidol  (ISO)
hexachlorobenzene  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoflavones  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
ketamine  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
mifepristone  (ISO)
mitoxantrone  (ISO)
Monobutylphthalate  (EXP)
monosodium L-glutamate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
naphthalene  (EXP,ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
nonanedioic acid  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-toluidine  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PD 0325901  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
poly(I:C)  (EXP)
potassium dichromate  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sirolimus  (ISO)
sirtinol  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
Soman  (ISO)
streptozocin  (EXP)
succimer  (ISO)
sulfasalazine  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
thalidomide  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
tioguanine  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tremolite asbestos  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vandetanib  (ISO)
vinclozolin  (ISO)
zearalenone  (ISO)
zebularine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
PMID:7505465   PMID:7510770   PMID:7511095   PMID:7525452   PMID:7529732   PMID:7679139   PMID:7684980   PMID:7750499   PMID:8398121   PMID:8833235   PMID:8889548   PMID:8923818  
PMID:9093203   PMID:9202255   PMID:9324049   PMID:9659293   PMID:9662407   PMID:9685224   PMID:9785199   PMID:10349636   PMID:10502456   PMID:10579362   PMID:10744620   PMID:10922068  
PMID:10976924   PMID:11033447   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11239426   PMID:11316761   PMID:11735249   PMID:12376320   PMID:12477932   PMID:12933651   PMID:14584894  
PMID:14651920   PMID:15142957   PMID:15485880   PMID:15550509   PMID:15592512   PMID:15721138   PMID:15731112   PMID:15747579   PMID:15761081   PMID:15809042   PMID:16002520   PMID:16019424  
PMID:16047381   PMID:16141072   PMID:16141073   PMID:16185287   PMID:16230333   PMID:16297183   PMID:16311053   PMID:16338473   PMID:16469805   PMID:16602821   PMID:16617154   PMID:16675541  
PMID:16813524   PMID:16983336   PMID:17158062   PMID:17255210   PMID:17278996   PMID:17332154   PMID:17388800   PMID:17434920   PMID:17567755   PMID:17567756   PMID:17591901   PMID:18212051  
PMID:18221414   PMID:18568074   PMID:18924579   PMID:18952711   PMID:18973680   PMID:19141684   PMID:19158946   PMID:19236847   PMID:19556345   PMID:19647223   PMID:19777566   PMID:19952275  
PMID:20007694   PMID:20080568   PMID:20111592   PMID:20473871   PMID:20926583   PMID:20937270   PMID:21245162   PMID:21325425   PMID:21383009   PMID:21435441   PMID:21447628   PMID:21677750  
PMID:21697095   PMID:21697285   PMID:21820362   PMID:21873635   PMID:21931131   PMID:22034491   PMID:22281475   PMID:22560297   PMID:22688304   PMID:22792172   PMID:22910030   PMID:23213481  
PMID:23525041   PMID:23584732   PMID:23813480   PMID:23836030   PMID:23868984   PMID:24006456   PMID:24194600   PMID:24358328   PMID:24952961   PMID:24990151   PMID:25082650   PMID:25490144  
PMID:25614235   PMID:26073647   PMID:26134413   PMID:26816005   PMID:27131881   PMID:27224923   PMID:27253188   PMID:27377812   PMID:27448965   PMID:27626380   PMID:27668656   PMID:27732088  
PMID:27861515   PMID:28088287   PMID:28330997   PMID:28663440   PMID:28807942   PMID:29217518   PMID:30419192   PMID:30454898   PMID:30581279   PMID:31526985   PMID:32106295   PMID:32290105  
PMID:32640236   PMID:33153107   PMID:33505018  


Genomics

Comparative Map Data
Igfbp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,156,086 - 7,165,498 (-)NCBIGRCm39mm39
GRCm39 Ensembl117,156,086 - 7,163,923 (-)Ensembl
GRCm38117,206,086 - 7,215,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,206,086 - 7,213,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv37117,106,089 - 7,113,926 (-)NCBIGRCm37mm9NCBIm37
MGSCv36117,108,384 - 7,113,834 (-)NCBImm8
Celera117,681,286 - 7,689,161 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
IGFBP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl745,912,245 - 45,921,874 (-)EnsemblGRCh38hg38GRCh38
GRCh38745,912,245 - 45,921,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37745,951,844 - 45,960,871 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,918,369 - 45,927,396 (-)NCBINCBI36hg18NCBI36
Build 34745,725,189 - 45,734,057NCBI
Celera746,050,761 - 46,059,785 (-)NCBI
Cytogenetic Map7p12.3NCBI
HuRef745,836,799 - 45,845,824 (-)NCBIHuRef
CHM1_1745,956,047 - 45,965,072 (-)NCBICHM1_1
CRA_TCAGchr7v2745,991,173 - 46,000,198 (-)NCBI
Igfbp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21482,056,347 - 82,064,083 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1482,056,347 - 82,064,083 (-)Ensembl
Rnor_6.01487,457,647 - 87,465,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,457,647 - 87,465,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,091,987 - 81,099,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,959,153 - 87,967,085 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11487,978,297 - 87,986,223 (-)NCBI
Celera1481,130,767 - 81,138,473 (-)NCBICelera
RH 3.4 Map14598.5RGD
Cytogenetic Map14q21NCBI
Igfbp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,795,604 - 6,800,845 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,795,560 - 6,802,147 (+)NCBIChiLan1.0ChiLan1.0
IGFBP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1746,681,856 - 46,690,240 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0746,564,234 - 46,573,145 (-)NCBIMhudiblu_PPA_v0panPan3
IGFBP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,021,855 - 1,027,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,021,972 - 1,026,392 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha161,797,939 - 1,804,689 (+)NCBI
ROS_Cfam_1.0161,008,571 - 1,015,327 (+)NCBI
UMICH_Zoey_3.116999,220 - 1,005,969 (+)NCBI
UNSW_CanFamBas_1.016934,846 - 941,592 (+)NCBI
UU_Cfam_GSD_1.016233,123 - 239,875 (-)NCBI
Igfbp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,299,235 - 101,306,540 (-)NCBI
SpeTri2.0NW_00493647820,511,490 - 20,518,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11850,002,921 - 50,009,425 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,851,168 - 54,855,699 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap18q24NCBI
IGFBP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,905,309 - 12,914,199 (+)NCBI
ChlSab1.1 Ensembl2112,905,280 - 12,914,205 (+)Ensembl
Vero_WHO_p1.0NW_0236660629,622,694 - 9,631,602 (-)NCBI
Igfbp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247406,878,818 - 6,886,512 (+)NCBI

Position Markers
Igfbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37117,108,457 - 7,110,066UniSTSGRCm37
Celera117,683,654 - 7,685,263UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.35UniSTS
cM Map111.35UniSTS
AI649005  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,206,747 - 7,206,885UniSTSGRCm38
MGSCv37117,106,750 - 7,106,888UniSTSGRCm37
Celera117,681,947 - 7,682,085UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.35UniSTS
Whitehead/MRC_RH1140.43UniSTS
Igfbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
Igfbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,208,454 - 7,210,063UniSTSGRCm38
MGSCv37117,108,457 - 7,110,066UniSTSGRCm37
Celera117,683,654 - 7,685,263UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.35UniSTS
Igfbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123930487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11126026374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11126026374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11126026374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1127705234277232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11272035536721472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11330000018200000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11330000018500000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11330000019800000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11330000034600000Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11330000044200000Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1301634Eae6a_msusceptibility to experimental allergic encephalomyelitis 6a (mouse)Not determined11455789621429532Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11455789621429532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11470000046400000Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11530000035200000Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11693027733966219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226794Feml9_mfemur length 9, 5 week (mouse)11710000016800000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:592
Count of miRNA genes:427
Interacting mature miRNAs:494
Transcripts:ENSMUST00000020702, ENSMUST00000135887
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020702   ⟹   ENSMUSP00000020702
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl117,156,086 - 7,163,897 (-)Ensembl
GRCm38.p6 Ensembl117,206,086 - 7,213,897 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135887   ⟹   ENSMUSP00000131670
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl117,157,686 - 7,163,923 (-)Ensembl
GRCm38.p6 Ensembl117,207,686 - 7,213,923 (-)Ensembl
RefSeq Acc Id: NM_008343   ⟹   NP_032369
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39117,156,086 - 7,163,923 (-)NCBI
GRCm38117,206,086 - 7,213,923 (-)NCBI
MGSCv37117,106,089 - 7,113,926 (-)RGD
Celera117,681,286 - 7,689,161 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243665   ⟹   XP_011241967
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39117,156,086 - 7,165,498 (-)NCBI
GRCm38117,206,086 - 7,215,498 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032369   ⟸   NM_008343
- Peptide Label: precursor
- UniProtKB: P47878 (UniProtKB/Swiss-Prot),   Q3UR87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241967   ⟸   XM_011243665
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000020702   ⟸   ENSMUST00000020702
RefSeq Acc Id: ENSMUSP00000131670   ⟸   ENSMUST00000135887
Promoters
RGD ID:6821098
Promoter ID:MM_KWN:6401
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney
Transcripts:OTTMUST00000011487,   OTTMUST00000011488
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36117,113,671 - 7,114,171 (-)MPROMDB
RGD ID:8673934
Promoter ID:EPDNEW_M14998
Type:multiple initiation site
Name:Igfbp3_1
Description:Mus musculus insulin-like growth factor binding protein 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38117,213,923 - 7,213,983EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96438 AgrOrtholog
Ensembl Genes ENSMUSG00000020427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000020702 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000131670 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020702 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000135887 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_1-6_chordata UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin_GF-bd_Cys-rich_CS UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16009 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96438 ENTREZGENE
NCBI Gene 16009 ENTREZGENE
PANTHER PTHR11551:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IGFBP UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IGFBP3 RGD
PhenoGen Igfbp3 PhenoGen
PRINTS IGFBPFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBPFAMILY3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IGFBP_N_1 UniProtKB/Swiss-Prot
  IGFBP_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00121 UniProtKB/Swiss-Prot
  SM00211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57610 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt IBP3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UR87 ENTREZGENE, UniProtKB/TrEMBL
  Q8BP94_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6PE62 UniProtKB/Swiss-Prot