Il6 (interleukin 6) - Rat Genome Database

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Gene: Il6 (interleukin 6) Mus musculus
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Symbol: Il6
Name: interleukin 6
RGD ID: 10802
MGI Page MGI
Description: Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including animal organ development; positive regulation of macromolecule metabolic process; and regulation of peptide hormone secretion. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including cellular response to cytokine stimulus; regulation of gene expression; and salivary gland morphogenesis. Located in external side of plasma membrane and extracellular space. Part of interleukin-6 receptor complex. Is expressed in several structures, including adrenal gland; genitourinary system; gut; liver; and thymus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B-cell hybridoma growth factor; Il; Il-6; interleukin HP-1; interleukin-6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,218,112 - 30,224,973 (+)NCBIGRCm39mm39
GRCm39 Ensembl530,218,112 - 30,224,979 (+)Ensembl
GRCm38530,013,114 - 30,019,975 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,013,114 - 30,019,981 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,339,701 - 30,346,508 (+)NCBIGRCm37mm9NCBIm37
MGSCv36530,343,948 - 30,350,755 (+)NCBImm8
Celera527,530,266 - 27,537,070 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map515.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model