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Gene: Clu (clusterin) Mus musculus
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Symbol: Clu
Name: clusterin
RGD ID: 68979
Description: Predicted to have several functions, including amyloid-beta binding activity; low-density lipoprotein particle receptor binding activity; and misfolded protein binding activity. Involved in immune complex clearance; positive regulation of cell death; and regulation of protein metabolic process. Localizes to several cellular components, including cytosol; mitochondrion; and synapse. Predicted to colocalize with cell periphery; cytoskeleton; and membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Orthologous to human CLU (clusterin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A; AI893575; apo-J; ApoJ; Apolipoprotein J; C; Cli; clustrin; complement lysis inhibitor; D14Ucl; D14Ucla3; Sg; Sgp; Sgp-2; Sgp2; SP-; SP-40; Sugp; Sugp-2; sulfated glycoprotein 2; testosterone repressed prostate message; testosterone repressed prostate message-2
Orthologs:
Homo sapiens (human) : CLU (clusterin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clu (clusterin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clu (clusterin)
Pan paniscus (bonobo/pygmy chimpanzee) : CLU (clusterin)
Canis lupus familiaris (dog) : CLU (clusterin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clu (clusterin)
Sus scrofa (pig) : CLU (clusterin)
Chlorocebus sabaeus (African green monkey) : CLU (clusterin)
Heterocephalus glaber (naked mole-rat) : Clu (clusterin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1465,968,483 - 65,981,547 (+)EnsemblGRCm38mm10GRCm38
GRCm381465,968,483 - 65,981,548 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371466,587,320 - 66,600,382 (+)NCBIGRCm37mm9NCBIm37
MGSCv361464,922,735 - 64,935,658 (+)NCBImm8
Celera1451,264,543 - 51,272,775 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Clu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68979
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.