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Gene: Clu (clusterin) Mus musculus
Symbol: Clu
Name: clusterin
RGD ID: 68979
Description: Predicted to have several functions, including amyloid-beta binding activity; low-density lipoprotein particle receptor binding activity; and misfolded protein binding activity. Involved in immune complex clearance; positive regulation of cell death; and regulation of protein metabolic process. Localizes to several cellular components, including cytosol; mitochondrion; and synapse. Predicted to colocalize with cell periphery; cytoskeleton; and membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Orthologous to human CLU (clusterin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A; AI893575; apo-J; ApoJ; Apolipoprotein J; C; Cli; clustrin; complement lysis inhibitor; D14Ucl; D14Ucla3; Sg; Sgp; Sgp-2; Sgp2; SP-; SP-40; Sugp; Sugp-2; sulfated glycoprotein 2; testosterone repressed prostate message; testosterone repressed prostate message-2
Homo sapiens (human) : CLU (clusterin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clu (clusterin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clu (clusterin)
Pan paniscus (bonobo/pygmy chimpanzee) : CLU (clusterin)
Canis lupus familiaris (dog) : CLU (clusterin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clu (clusterin)
Sus scrofa (pig) : CLU (clusterin)
Chlorocebus sabaeus (African green monkey) : CLU (clusterin)
Heterocephalus glaber (naked mole-rat) : Clu (clusterin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1465,968,483 - 65,981,547 (+)EnsemblGRCm38mm10GRCm38
GRCm381465,968,483 - 65,981,548 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371466,587,320 - 66,600,382 (+)NCBIGRCm37mm9NCBIm37
MGSCv361464,922,735 - 64,935,658 (+)NCBImm8
Celera1451,264,543 - 51,272,775 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Clu
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68979
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.