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Gene: Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha) Mus musculus
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Symbol: Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Description: Exhibits chromatin DNA binding activity; transcription coactivator activity; and transcription factor binding activity. Involved in several processes, including circadian regulation of gene expression; energy homeostasis; and regulation of nucleobase-containing compound metabolic process. Localizes to nucleus. Is expressed in several structures, including adipose tissue; central nervous system; heart; hindlimb digit mesenchyme; and sensory organ. Used to study age related macular degeneration; cardiomyopathy; and congestive heart failure. Human ortholog(s) of this gene implicated in several diseases, including macular degeneration; malignant fibrous histiocytoma; neurodegenerative disease (multiple); non-alcoholic fatty liver disease; and type 2 diabetes mellitus. Orthologous to human PPARGC1A (PPARG coactivator 1 alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A830037N07Rik; ENSMUSG00000079510; Gm11133; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; peroxisome proliferator-activated receptor gamma coactivator-1 alpha; PGC-1; PGC-1-alpha; Pgc-1alpha; Pgc-1alphaa; PGC-1v; Pgc1; Pgco1; PPAR gamma coactivator variant form; PPAR Gamma Coactivator-1; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ppargc1
Orthologs:
Homo sapiens (human) : PPARGC1A (PPARG coactivator 1 alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppargc1a (PPARG coactivator 1 alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppargc1a (PPARG coactivator 1 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : PPARGC1A (PPARG coactivator 1 alpha)
Canis lupus familiaris (dog) : PPARGC1A (PPARG coactivator 1 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppargc1a (PPARG coactivator 1 alpha)
Sus scrofa (pig) : PPARGC1A (PPARG coactivator 1 alpha)
Chlorocebus sabaeus (African green monkey) : PPARGC1A (PPARG coactivator 1 alpha)
Heterocephalus glaber (naked mole-rat) : Ppargc1a (PPARG coactivator 1 alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl551,454,250 - 51,567,726 (-)EnsemblGRCm38mm10GRCm38
GRCm38551,454,249 - 52,115,853 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37551,845,488 - 51,945,160 (-)NCBIGRCm37mm9NCBIm37
MGSCv36551,745,901 - 51,842,109 (-)NCBImm8
Celera548,830,811 - 48,929,055 (-)NCBICelera
Cytogenetic Map5C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences