(+)-schisandrin B multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR1C2 mRNA] CTD PMID:31150632 (-)-epigallocatechin 3-gallate increases expression ISO AKR1C2 (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of AKR1C2 mRNA CTD PMID:32512070 (20S)-20-hydroxypregn-4-en-3-one increases chemical synthesis ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:11158055 (E)-cinnamyl alcohol increases activity ISO AKR1C2 (Homo sapiens) 6480464 cinnamyl alcohol results in increased activity of AKR1C2 promoter CTD PMID:21195160 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO AKR1C2 (Homo sapiens) 6480464 o and p'-DDT results in increased expression of AKR1C2 mRNA CTD PMID:18204070 1,10-phenanthroline decreases activity ISO AKR1C2 (Homo sapiens) 6480464 1 and 10-phenanthroline results in decreased activity of AKR1C2 protein CTD PMID:12604236 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of AKR1C21 mRNA CTD PMID:22206623 1,3-benzothiazole-2-thiol increases expression ISO AKR1C2 (Homo sapiens) 6480464 captax results in increased expression of AKR1C2 mRNA CTD PMID:20491607 and PMID:20713136 1,3-benzothiazole-2-thiol increases activity ISO AKR1C2 (Homo sapiens) 6480464 captax results in increased activity of AKR1C2 promoter CTD PMID:21195160 1,4-benzoquinone increases expression ISO AKR1C2 (Homo sapiens) 6480464 quinone results in increased expression of AKR1C2 mRNA CTD PMID:20491607 1,4-phenylenediamine increases activity ISO AKR1C2 (Homo sapiens) 6480464 4-phenylenediamine results in increased activity of AKR1C2 promoter CTD PMID:21195160 1,4-phenylenediamine increases expression ISO AKR1C2 (Homo sapiens) 6480464 4-phenylenediamine results in increased expression of AKR1C2 mRNA CTD PMID:20491607 and PMID:25724174 1-chloro-2,4-dinitrobenzene increases activity ISO AKR1C2 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased activity of AKR1C2 promoter CTD PMID:21195160 1-chloro-2,4-dinitrobenzene increases expression ISO AKR1C2 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of AKR1C2 mRNA CTD PMID:20491607 and PMID:20713136 1-phenyl-1,2-propanedione increases expression ISO AKR1C2 (Homo sapiens) 6480464 1-phenyl-1 and 2-propanedione results in increased expression of AKR1C2 mRNA CTD PMID:20491607 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of AKR1C21 mRNA CTD PMID:17555576 17beta-estradiol multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AKR1C2 mRNA CTD PMID:19619570 17beta-estradiol increases expression ISO AKR1C2 (Homo sapiens) 6480464 Estradiol results in increased expression of AKR1C2 mRNA CTD PMID:19619570 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased metabolism of and results in decreased activity of Dihydrotestosterone and Flufenamic Acid inhibits the reaction [AKR1C2 protein results in increased metabolism of Dihydrotestosterone] CTD PMID:14672942 and PMID:17170221 17beta-hydroxy-5alpha-androstan-3-one increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of Dihydrotestosterone CTD PMID:11158055 17beta-hydroxy-5alpha-androstan-3-one increases metabolic processing ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased metabolism of Dihydrotestosterone CTD PMID:14672942 and PMID:22245609 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO AKR1C2 (Homo sapiens) 6480464 2 more ... CTD PMID:25305463 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1C2 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AKR1C2 mRNA CTD PMID:19619570 2,4,6-trinitrobenzenesulfonic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25724174 2-(chloromethyl)pyridine increases expression ISO AKR1C2 (Homo sapiens) 6480464 2-chloromethylpyridine results in increased expression of AKR1C2 mRNA CTD PMID:26198647 2-aminophenol increases expression ISO AKR1C2 (Homo sapiens) 6480464 2-aminophenol results in increased expression of AKR1C2 mRNA CTD PMID:20491607 2-hexenal increases expression ISO AKR1C2 (Homo sapiens) 6480464 2-hexenal results in increased expression of AKR1C2 mRNA CTD PMID:20491607 2-hydroxyethyl methacrylate increases expression ISO AKR1C2 (Homo sapiens) 6480464 hydroxyethyl methacrylate results in increased expression of AKR1C2 mRNA CTD PMID:30497689 2-palmitoylglycerol increases expression ISO AKR1C2 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of AKR1C2 mRNA CTD PMID:37199045 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 [3 more ... CTD PMID:30744511 3,3',5-triiodo-L-thyronine increases expression ISO AKR1C2 (Homo sapiens) 6480464 Triiodothyronine results in increased expression of AKR1C2 mRNA CTD PMID:15507505 3,4,5,3',4',5'-Hexachlorobiphenyl multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 [3 more ... CTD PMID:30744511 3,4-dichloroaniline increases expression ISO AKR1C2 (Homo sapiens) 6480464 3 and 4-dichloroaniline results in increased expression of AKR1C2 mRNA CTD PMID:24172598 3-Nitrobenzanthrone increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone CTD PMID:30406992 3-Nitrobenzanthrone multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone and [AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone CTD PMID:30406992 3-phenylprop-2-enal increases expression ISO AKR1C2 (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of AKR1C2 mRNA CTD PMID:25724174 and PMID:26244607 3-phenylprop-2-enal increases activity ISO AKR1C2 (Homo sapiens) 6480464 cinnamaldehyde results in increased activity of AKR1C2 promoter CTD PMID:21195160 3-phenylprop-2-enal multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 NFE2L2 mRNA promotes the reaction [cinnamaldehyde results in increased expression of AKR1C2 mRNA] CTD PMID:26244607 3alpha-hydroxy-5beta-pregnan-20-one affects metabolic processing ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the metabolism of Pregnanolone CTD PMID:12604236 3alpha-hydroxy-5beta-pregnan-20-one increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of Pregnanolone CTD PMID:11995921 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AKR1C21 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO AKR1C2 (Homo sapiens) 6480464 bisphenol S results in increased expression of AKR1C2 protein CTD PMID:34186270 4-(ethoxymethylene)-2-phenyloxazol-5-one increases activity ISO AKR1C2 (Homo sapiens) 6480464 Oxazolone results in increased activity of AKR1C2 promoter CTD PMID:21195160 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases metabolic processing ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11306090 4-hydroxybenzoic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 4-hydroxybenzoic acid analog results in decreased activity of AKR1C2 protein CTD PMID:27163852 4-nitro-1,2-phenylenediamine increases expression ISO AKR1C2 (Homo sapiens) 6480464 1 and 2-diamino-4-nitrobenzene results in increased expression of AKR1C2 mRNA CTD PMID:26198647 4-nitrobenzyl bromide increases activity ISO AKR1C2 (Homo sapiens) 6480464 4-nitrobenzyl bromide results in increased activity of AKR1C2 promoter CTD PMID:21195160 4-nitrobenzyl bromide increases expression ISO AKR1C2 (Homo sapiens) 6480464 4-nitrobenzyl bromide results in increased expression of AKR1C2 mRNA CTD PMID:25724174 5-alpha-THDOC affects oxidation ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the oxidation of tetrahydrodeoxycorticosterone CTD PMID:12604236 5-fluorouracil affects response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 5alpha-pregnane-3,20-dione affects reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the reduction of 5-alpha-Dihydroprogesterone CTD PMID:12604236 5alpha-pregnane-3,20-dione increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of 5-alpha-Dihydroprogesterone CTD PMID:11995921 9,10-phenanthroquinone increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of 9 and 10-phenanthrenequinone CTD PMID:21851338 and PMID:23261716 9,10-phenanthroquinone multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of and affects the activity of 9 and 10-phenanthrenequinone CTD PMID:21910479 9,10-phenanthroquinone increases metabolic processing ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased metabolism of 9 and 10-phenanthrenequinone CTD PMID:17950253 acetylsalicylic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Aspirin results in decreased activity of AKR1C2 protein CTD PMID:19010312 acrylamide decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of AKR1C2 mRNA CTD PMID:28959563 adefovir pivoxil decreases expression ISO AKR1C2 (Homo sapiens) 6480464 adefovir dipivoxil results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 aflatoxin B1 decreases methylation ISO AKR1C2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of AKR1C2 gene CTD PMID:27153756 ampicillin decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Ampicillin results in decreased expression of AKR1C2 mRNA CTD PMID:21632981 androstane-3,17-diol increases chemical synthesis ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased chemical synthesis of Androstane-3 and 17-diol CTD PMID:11158055 and PMID:17170221 arsane multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C2 mRNA CTD PMID:32525701 arsane increases expression ISO AKR1C2 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C2 mRNA CTD PMID:36861143 arsenic atom multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C2 mRNA CTD PMID:32525701 arsenic atom increases expression ISO AKR1C2 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C2 mRNA CTD PMID:36861143 arsenous acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C2 mRNA CTD PMID:21461292 and PMID:26705709 arsenous acid multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C2 protein] CTD PMID:26598702 arsenous acid decreases response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 avobenzone increases expression ISO AKR1C2 (Homo sapiens) 6480464 avobenzone results in increased expression of AKR1C2 mRNA CTD PMID:31016361 azathioprine increases expression ISO AKR1C2 (Homo sapiens) 6480464 Azathioprine results in increased expression of AKR1C2 mRNA CTD PMID:22623647 and PMID:26198647 benzbromarone decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Benzbromarone results in decreased activity of AKR1C2 protein CTD PMID:12604236 benzo[a]pyrene multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Particulate Matter co-treated with Benzo(a)pyrene] results in increased expression of AKR1C2 mRNA more ... CTD PMID:17612574 and PMID:19800895 benzo[a]pyrene affects methylation ISO AKR1C2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of AKR1C2 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA CTD PMID:18353537 benzo[a]pyrene increases expression ISO AKR1C2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of AKR1C2 mRNA CTD PMID:15735009 more ... benzo[a]pyrene affects response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:19800895 benzo[a]pyrene diol epoxide I increases expression ISO AKR1C2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 Benzo[a]pyrene-7,8-diol multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 and 8-dihydrodiol CTD PMID:21910479 benzo[a]pyrene-7,8-dione multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 and 8-dione CTD PMID:21910479 benzyl cinnamate increases expression ISO AKR1C2 (Homo sapiens) 6480464 benzyl cinnamate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 bis(2-ethylhexyl) phthalate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of AKR1C2 mRNA CTD PMID:28412506 bisphenol A affects expression ISO AKR1C2 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR1C2 mRNA CTD PMID:30903817 bisphenol A decreases methylation ISO AKR1C2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of AKR1C2 gene CTD PMID:31601247 bisphenol A affects expression ISO Akr1c2 (Rattus norvegicus) 6480464 bisphenol A affects the expression of AKR1C2 mRNA CTD PMID:30903817 Bisphenol B increases expression ISO AKR1C2 (Homo sapiens) 6480464 bisphenol B results in increased expression of AKR1C2 protein CTD PMID:34186270 bisphenol F increases expression ISO AKR1C2 (Homo sapiens) 6480464 bisphenol F results in increased expression of AKR1C2 protein CTD PMID:34186270 bortezomib affects expression ISO AKR1C2 (Homo sapiens) 6480464 Bortezomib affects the expression of AKR1C2 mRNA CTD PMID:21215737 cadmium atom increases expression ISO AKR1C2 (Homo sapiens) 6480464 Cadmium results in increased expression of AKR1C2 mRNA CTD PMID:21120746 and PMID:21172416 cadmium atom multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C2 mRNA CTD PMID:29741670 cadmium dichloride affects expression ISO AKR1C2 (Homo sapiens) 6480464 Cadmium Chloride affects the expression of AKR1C2 mRNA CTD PMID:23828170 cadmium dichloride multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C2 mRNA CTD PMID:29741670 cadmium dichloride increases expression ISO AKR1C2 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of AKR1C2 mRNA CTD PMID:25596134 cadmium sulfate multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA CTD PMID:18654764 celastrol increases expression ISO AKR1C2 (Homo sapiens) 6480464 celastrol results in increased expression of AKR1C2 mRNA CTD PMID:17010675 chenodeoxycholic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Chenodeoxycholic Acid results in decreased activity of AKR1C2 protein CTD PMID:8573067 chenodeoxycholic acid affects binding ISO AKR1C2 (Homo sapiens) 6480464 Chenodeoxycholic Acid binds to AKR1C2 protein CTD PMID:8486699 chlorambucil decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Chlorambucil results in decreased expression of AKR1C2 mRNA CTD PMID:26198647 chloroacetaldehyde increases expression ISO AKR1C2 (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of AKR1C2 mRNA CTD PMID:25596134 chlorohydrocarbon multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of AKR1C2 mRNA CTD PMID:30744511 chloromethylisothiazolinone increases activity ISO AKR1C2 (Homo sapiens) 6480464 5-chloro-2-methyl-4-isothiazolin-3-one results in increased activity of AKR1C2 promoter CTD PMID:21195160 chloropicrin affects expression ISO AKR1C2 (Homo sapiens) 6480464 chloropicrin affects the expression of AKR1C2 mRNA CTD PMID:26352163 chloropicrin increases expression ISO AKR1C2 (Homo sapiens) 6480464 chloropicrin results in increased expression of AKR1C2 mRNA CTD PMID:28476498 cidofovir anhydrous affects expression ISO AKR1C2 (Homo sapiens) 6480464 Cidofovir affects the expression of AKR1C2 mRNA CTD PMID:25596134 ciglitazone multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C2 mRNA and [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C2 mRNA CTD PMID:16197558 cinnamyl alcohol increases activity ISO AKR1C2 (Homo sapiens) 6480464 cinnamyl alcohol results in increased activity of AKR1C2 promoter CTD PMID:21195160 cisplatin decreases response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in decreased susceptibility to Cisplatin CTD PMID:20953859 cisplatin multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C2 mRNA CTD PMID:27392435 cisplatin increases expression ISO AKR1C2 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR1C2 mRNA CTD PMID:25596134 cisplatin decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of AKR1C2 mRNA CTD PMID:26198647 citral increases activity ISO AKR1C2 (Homo sapiens) 6480464 citral results in increased activity of AKR1C2 promoter CTD PMID:21195160 citral increases expression ISO AKR1C2 (Homo sapiens) 6480464 citral results in increased expression of AKR1C2 mRNA CTD PMID:20491607 clodronic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Clodronic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25596134 Clofop increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of fenofibric acid CTD PMID:27599626 cloxazolam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 cloxazolam results in decreased activity of AKR1C2 protein CTD PMID:12604236 cobalt dichloride multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA CTD PMID:18654764 coniferyl aldehyde increases expression ISO AKR1C2 (Homo sapiens) 6480464 coniferaldehyde results in increased expression of AKR1C2 mRNA and coniferaldehyde results in increased expression of AKR1C2 protein CTD PMID:26275128 copper atom multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C2 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C2 mRNA CTD PMID:20971185 crocidolite asbestos decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of AKR1C2 mRNA CTD PMID:18687144 Cuprizon decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of AKR1C2 mRNA CTD PMID:26577399 cyclopentanol increases oxidation ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased oxidation of cyclopentanol CTD PMID:23261716 cyclopentanone multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone more ... CTD PMID:23261716 cyclopentanone increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of cyclopentanone CTD PMID:23261716 cyclosporin A increases expression ISO AKR1C2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of AKR1C2 mRNA CTD PMID:22147139 more ... diarsenic trioxide increases expression ISO AKR1C2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C2 mRNA CTD PMID:21461292 and PMID:26705709 diarsenic trioxide multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C2 protein] CTD PMID:26598702 diarsenic trioxide decreases response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 diazepam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Diazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 and PMID:12604236 dibenzo[a,l]pyrene multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Particulate Matter co-treated with dibenzo(a more ... CTD PMID:17612574 dienogest decreases expression ISO AKR1C2 (Homo sapiens) 6480464 dienogest results in decreased expression of AKR1C2 mRNA CTD PMID:23183084 diethyl maleate increases expression ISO AKR1C2 (Homo sapiens) 6480464 diethyl maleate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 diethyl sulfate increases expression ISO AKR1C2 (Homo sapiens) 6480464 diethyl sulfate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 dioxygen decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Antimony Potassium Tartrate results in increased expression of AKR1C2 protein CTD PMID:28713220 diquat increases expression ISO AKR1C2 (Homo sapiens) 6480464 Diquat results in increased expression of AKR1C2 mRNA CTD PMID:21172416 diuron increases expression ISO AKR1C2 (Homo sapiens) 6480464 Diuron metabolite results in increased expression of AKR1C2 mRNA CTD PMID:24172598 dorsomorphin multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of AKR1C2 mRNA CTD PMID:29803840 dutasteride increases expression ISO AKR1C2 (Homo sapiens) 6480464 Dutasteride results in increased expression of AKR1C2 mRNA CTD PMID:16806904 dydrogesterone decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Dydrogesterone results in decreased activity of AKR1C2 protein CTD PMID:22245609 dydrogesterone decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Dydrogesterone results in decreased expression of AKR1C2 mRNA CTD PMID:23183084 entinostat decreases expression ISO AKR1C2 (Homo sapiens) 6480464 entinostat results in decreased expression of AKR1C2 mRNA CTD PMID:27188386 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of AKR1C21 mRNA CTD PMID:35436446 estazolam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Estazolam results in decreased activity of AKR1C2 protein CTD PMID:11995921 Ethyl acrylate increases expression ISO AKR1C2 (Homo sapiens) 6480464 ethyl acrylate results in increased expression of AKR1C2 mRNA CTD PMID:26198647 ethyl methanesulfonate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of AKR1C2 mRNA CTD PMID:23649840 ethylene glycol dimethacrylate increases activity ISO AKR1C2 (Homo sapiens) 6480464 ethylene dimethacrylate results in increased activity of AKR1C2 promoter CTD PMID:21195160 ethylparaben increases expression ISO AKR1C2 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of AKR1C2 mRNA CTD PMID:37690743 eugenol increases expression ISO AKR1C2 (Homo sapiens) 6480464 Eugenol results in increased expression of AKR1C2 mRNA CTD PMID:26198647 farnesal increases expression ISO AKR1C2 (Homo sapiens) 6480464 farnesal results in increased expression of AKR1C2 mRNA CTD PMID:20491607 fenamic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 fenamic acid analog results in decreased activity of AKR1C2 protein CTD PMID:19010312 fenofibrate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Fenofibrate results in increased expression of AKR1C2 mRNA CTD PMID:25596134 flufenamic acid multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 Flufenamic Acid inhibits the reaction [AKR1C2 protein results in increased metabolism of Dihydrotestosterone] CTD PMID:14672942 flufenamic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Flufenamic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 and PMID:8573067 flunitrazepam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Flunitrazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 fluorescein 5-isothiocyanate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 flurbiprofen decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Flurbiprofen results in decreased activity of AKR1C2 protein CTD PMID:19010312 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of AKR1C21 mRNA CTD PMID:25629700 formaldehyde increases expression ISO AKR1C2 (Homo sapiens) 6480464 Formaldehyde results in increased expression of AKR1C2 mRNA CTD PMID:20491607 and PMID:20655997 gedunin increases expression ISO AKR1C2 (Homo sapiens) 6480464 gedunin results in increased expression of AKR1C2 mRNA CTD PMID:17010675 geranial increases activity ISO AKR1C2 (Homo sapiens) 6480464 citral results in increased activity of AKR1C2 promoter CTD PMID:21195160 geranial increases expression ISO AKR1C2 (Homo sapiens) 6480464 citral results in increased expression of AKR1C2 mRNA CTD PMID:20491607 glipizide decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Glipizide results in decreased activity of AKR1C2 protein CTD PMID:26362498 glyburide decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Glyburide results in decreased activity of AKR1C2 protein CTD PMID:26362498 glycyrrhetinate decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 glycyrrhetinic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 glyoxal increases expression ISO AKR1C2 (Homo sapiens) 6480464 Glyoxal results in increased expression of AKR1C2 mRNA CTD PMID:25724174 glyoxal increases activity ISO AKR1C2 (Homo sapiens) 6480464 Glyoxal results in increased activity of AKR1C2 promoter CTD PMID:21195160 gold atom increases expression ISO AKR1C2 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C2 mRNA CTD PMID:29705079 gold(0) increases expression ISO AKR1C2 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C2 mRNA CTD PMID:29705079 hexestrol decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Hexestrol results in decreased activity of AKR1C2 protein CTD PMID:12604236 and PMID:8573067 hydralazine multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1C2 mRNA CTD PMID:17183730 hydrogen peroxide increases expression ISO AKR1C2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of AKR1C2 mRNA CTD PMID:12414654 hydrogen peroxide multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 mRNA and [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 protein CTD PMID:19320734 hydrogen peroxide affects expression ISO AKR1C2 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of AKR1C2 mRNA CTD PMID:23410634 ibuprofen decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Ibuprofen results in decreased activity of AKR1C2 protein CTD PMID:19010312 and PMID:8573067 ifosfamide increases expression ISO AKR1C2 (Homo sapiens) 6480464 Ifosfamide results in increased expression of AKR1C2 mRNA CTD PMID:25596134 imidurea increases activity ISO AKR1C2 (Homo sapiens) 6480464 imidazolidinyl urea results in increased activity of AKR1C2 promoter CTD PMID:21195160 indometacin decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Indomethacin results in decreased activity of AKR1C2 protein CTD PMID:12604236 more ... isoeugenol increases activity ISO AKR1C2 (Homo sapiens) 6480464 isoeugenol results in increased activity of AKR1C2 promoter CTD PMID:21195160 isoeugenol increases expression ISO AKR1C2 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C2 mRNA CTD PMID:20491607 ivermectin decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR1C2 protein CTD PMID:32959892 L-ascorbic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Ascorbic Acid results in increased expression of AKR1C2 mRNA CTD PMID:26198647 lead diacetate increases expression ISO AKR1C2 (Homo sapiens) 6480464 lead acetate results in increased expression of AKR1C2 mRNA CTD PMID:22839698 lead(0) affects splicing ISO AKR1C2 (Homo sapiens) 6480464 Lead affects the splicing of AKR1C2 mRNA CTD PMID:28903495 lead(II) chloride increases expression ISO AKR1C2 (Homo sapiens) 6480464 lead chloride results in increased expression of AKR1C2 mRNA CTD PMID:18654764 lead(II) chloride multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA CTD PMID:18654764 linalool increases expression ISO AKR1C2 (Homo sapiens) 6480464 linalool results in increased expression of AKR1C2 mRNA CTD PMID:20491607 lithocholic acid affects binding ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein binds to Lithocholic Acid and Lithocholic Acid binds to AKR1C2 protein CTD PMID:8486699 and PMID:8573067 lithocholic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Lithocholic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 and PMID:8573067 malathion increases expression ISO AKR1C2 (Homo sapiens) 6480464 Malathion results in increased expression of AKR1C2 mRNA CTD PMID:16079077 meclofenamic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Meclofenamic Acid results in decreased activity of AKR1C2 protein CTD PMID:19010312 more ... Medazepam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Medazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 and PMID:12604236 medroxyprogesterone acetate decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in decreased activity of AKR1C2 protein CTD PMID:12604236 and PMID:22245609 mefenamic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Mefenamic Acid analog results in decreased activity of AKR1C2 protein CTD PMID:19010312 menadione increases expression ISO AKR1C2 (Homo sapiens) 6480464 Vitamin K 3 results in increased expression of AKR1C2 mRNA CTD PMID:12414654 and PMID:23410634 mercury dibromide increases expression ISO AKR1C2 (Homo sapiens) 6480464 mercuric bromide results in increased expression of AKR1C2 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA CTD PMID:27188386 methyl methanesulfonate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of AKR1C2 mRNA CTD PMID:23649840 methyl non-2-ynoate increases expression ISO AKR1C2 (Homo sapiens) 6480464 2-nonynoic acid methyl ester results in increased expression of AKR1C2 mRNA CTD PMID:20491607 methylmercury chloride increases expression ISO AKR1C2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of AKR1C2 mRNA CTD PMID:28001369 methylmercury chloride multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of AKR1C2 mRNA CTD PMID:30744511 n-propyl gallate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Propyl Gallate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NAD zwitterion multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol more ... CTD PMID:25446855 NAD(+) multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol more ... CTD PMID:25446855 NADP zwitterion multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:14672942 more ... NADP(+) multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:14672942 more ... naphthalenes multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 naproxen decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Naproxen results in decreased activity of AKR1C2 protein CTD PMID:19010312 nitrazepam decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Nitrazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 ochratoxin A decreases expression ISO AKR1C2 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of AKR1C2 mRNA CTD PMID:19287073 and PMID:32905824 ochratoxin A decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 ochratoxin A results in decreased expression of AKR1C2 mRNA CTD PMID:30449730 octadecanoic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 stearic acid results in increased expression of AKR1C2 mRNA CTD PMID:32347412 octyl gallate decreases activity ISO AKR1C2 (Homo sapiens) 6480464 octyl gallate results in decreased activity of AKR1C2 protein CTD PMID:27163852 oxcarbazepine increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of oxcarbazepine CTD PMID:25063510 p-chloromercuribenzoic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of AKR1C2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA CTD PMID:27188386 paclitaxel increases response to substance ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 mRNA results in increased susceptibility to Paclitaxel CTD PMID:16322897 para-Cresidine increases expression ISO AKR1C2 (Homo sapiens) 6480464 cresidine results in increased expression of AKR1C2 mRNA CTD PMID:26198647 paracetamol decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of AKR1C2 mRNA CTD PMID:29067470 Paraoxon-methyl increases expression ISO AKR1C2 (Homo sapiens) 6480464 methylparaoxon results in increased expression of AKR1C2 mRNA CTD PMID:19800895 Paraoxon-methyl multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with methylparaoxon] CTD PMID:19800895 parathion-methyl multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with Methyl Parathion] more ... CTD PMID:19800895 parathion-methyl increases expression ISO AKR1C2 (Homo sapiens) 6480464 Methyl Parathion results in increased expression of AKR1C2 mRNA CTD PMID:19800895 parathion-methyl increases activity ISO AKR1C2 (Homo sapiens) 6480464 Methyl Parathion results in increased activity of AKR1C2 protein CTD PMID:19800895 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of AKR1C2 mRNA CTD PMID:17681415 phenethyl caffeate decreases activity ISO AKR1C2 (Homo sapiens) 6480464 caffeic acid phenethyl ester results in decreased activity of AKR1C2 protein CTD PMID:27163852 phenobarbital increases expression ISO AKR1C2 (Homo sapiens) 6480464 Phenobarbital results in increased expression of AKR1C2 protein CTD PMID:35881160 phenolphthalein decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Phenolphthalein results in decreased activity of AKR1C2 protein CTD PMID:12604236 Phenyl glycidyl ether multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 phenylglycidyl ether analog promotes the reaction [NFE2L2 protein results in increased expression of AKR1C2 mRNA] CTD PMID:21751775 phenylacetaldehyde increases expression ISO AKR1C2 (Homo sapiens) 6480464 phenylacetaldehyde results in increased expression of AKR1C2 mRNA CTD PMID:20491607 phenylmercury acetate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of AKR1C2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA CTD PMID:18353537 phorbol 13-acetate 12-myristate decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA CTD PMID:26198647 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of AKR1C21 mRNA CTD PMID:20813756 pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in decreased expression of AKR1C2 mRNA] CTD PMID:18467677 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of AKR1C2 mRNA CTD PMID:18467677 potassium bromate increases expression ISO Akr1c2 (Rattus norvegicus) 6480464 potassium bromate results in increased expression of AKR1C2 mRNA CTD PMID:23588252 progesterone increases reduction ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased reduction of Progesterone CTD PMID:11158055 more ... prostaglandin F2alpha increases metabolic processing ISO AKR1C2 (Homo sapiens) 6480464 AKR1C2 protein results in increased metabolism of Dinoprost CTD PMID:8573067 quercetin decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Quercetin results in decreased expression of AKR1C2 mRNA CTD PMID:21632981 quinolin-8-ol increases expression ISO AKR1C2 (Homo sapiens) 6480464 Oxyquinoline results in increased expression of AKR1C2 mRNA CTD PMID:21632981 and PMID:26198647 reactive oxygen species multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 mRNA and [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 protein CTD PMID:19320734 rotenone decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of AKR1C2 mRNA CTD PMID:28374803 salicylic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Salicylic Acid results in increased expression of AKR1C2 mRNA CTD PMID:20491607 salicylic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Salicylic Acid results in decreased activity of AKR1C2 protein CTD PMID:19010312 SB 431542 multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide increases secretion ISO AKR1C2 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased secretion of AKR1C2 protein CTD PMID:25895662 silver atom increases expression ISO AKR1C2 (Homo sapiens) 6480464 Silver results in increased expression of AKR1C2 mRNA CTD PMID:28959546 silver(0) increases expression ISO AKR1C2 (Homo sapiens) 6480464 Silver results in increased expression of AKR1C2 mRNA CTD PMID:28959546 sodium arsenate multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C2 mRNA CTD PMID:32525701 sodium arsenite increases expression ISO AKR1C2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of AKR1C2 mRNA and sodium arsenite results in increased expression of AKR1C2 protein CTD PMID:19696165 more ... sodium dodecyl sulfate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 sulforaphane increases expression ISO AKR1C2 (Homo sapiens) 6480464 sulforaphane results in increased expression of AKR1C2 mRNA CTD PMID:24383545 and PMID:31746589 sulindac decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Sulindac results in decreased activity of AKR1C2 protein CTD PMID:19010312 tert-butyl hydroperoxide increases expression ISO AKR1C2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of AKR1C2 mRNA CTD PMID:12414654 more ... testosterone decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Testosterone results in decreased expression of AKR1C2 mRNA CTD PMID:33359661 testosterone enanthate affects expression ISO AKR1C2 (Homo sapiens) 6480464 testosterone enanthate affects the expression of AKR1C2 mRNA CTD PMID:17440010 tetrachloromethane decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of AKR1C2 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions ISO Akr1c2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR1C2 mRNA] CTD PMID:31150632 thioacetamide decreases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of AKR1C2 mRNA CTD PMID:34492290 thiram increases activity ISO AKR1C2 (Homo sapiens) 6480464 Thiram results in increased activity of AKR1C2 promoter CTD PMID:21195160 titanium dioxide decreases phosphorylation ISO AKR1C2 (Homo sapiens) 6480464 titanium dioxide results in decreased phosphorylation of AKR1C2 protein CTD PMID:21439344 trans-isoeugenol increases expression ISO AKR1C2 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C2 mRNA CTD PMID:20491607 trans-isoeugenol increases activity ISO AKR1C2 (Homo sapiens) 6480464 isoeugenol results in increased activity of AKR1C2 promoter CTD PMID:21195160 Tributyltin oxide increases expression ISO AKR1C2 (Homo sapiens) 6480464 bis(tri-n-butyltin)oxide results in increased expression of AKR1C2 mRNA CTD PMID:26198647 trichloroethene increases expression ISO Akr1c2 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of AKR1C2 mRNA CTD PMID:33387578 trichostatin A increases expression ISO AKR1C2 (Homo sapiens) 6480464 trichostatin A results in increased expression of AKR1C2 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA CTD PMID:27188386 tris(2-butoxyethyl) phosphate decreases expression ISO AKR1C2 (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate results in decreased expression of AKR1C2 mRNA CTD PMID:29024780 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of AKR1C21 mRNA CTD PMID:17127020 urethane decreases expression ISO AKR1C2 (Homo sapiens) 6480464 Urethane results in decreased expression of AKR1C2 mRNA CTD PMID:28818685 ursodeoxycholic acid multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone] CTD PMID:23261716 ursodeoxycholic acid decreases activity ISO AKR1C2 (Homo sapiens) 6480464 Ursodeoxycholic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 more ... valproic acid decreases methylation ISO AKR1C2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of AKR1C2 gene CTD PMID:29154799 valproic acid increases expression ISO AKR1C2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of AKR1C2 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1C2 mRNA more ... CTD PMID:17183730 and PMID:27188386 valproic acid affects expression ISO AKR1C2 (Homo sapiens) 6480464 Valproic Acid affects the expression of AKR1C2 mRNA CTD PMID:25979313 vanillin increases expression ISO AKR1C2 (Homo sapiens) 6480464 vanillin results in increased expression of AKR1C2 mRNA CTD PMID:20491607 vinclozolin decreases methylation ISO Akr1c2 (Rattus norvegicus) 6480464 vinclozolin results in decreased methylation of AKR1C2 gene CTD PMID:31079544 vitamin E increases expression ISO AKR1C2 (Homo sapiens) 6480464 Vitamin E results in increased expression of AKR1C2 mRNA CTD PMID:19244175 vorinostat multiple interactions ISO AKR1C2 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA CTD PMID:27188386 vorinostat increases expression ISO AKR1C2 (Homo sapiens) 6480464 vorinostat results in increased expression of AKR1C2 mRNA CTD PMID:26272509 zinc sulfate increases expression ISO AKR1C2 (Homo sapiens) 6480464 Zinc Sulfate results in increased expression of AKR1C2 mRNA CTD PMID:16330358 zoledronic acid decreases expression ISO AKR1C2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 zomepirac decreases activity ISO AKR1C2 (Homo sapiens) 6480464 zomepirac results in decreased activity of AKR1C2 protein CTD PMID:19010312