Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Foxd4 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FOXD4 mRNA | CTD | PMID:21570461 and PMID:24058054 | Foxd4 | Mouse | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:23146750 | Foxd4 | Mouse | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of FOXD4 mRNA | CTD | PMID:30951980 | Foxd4 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of FOXD4 mRNA | CTD | PMID:24780913 | Foxd4 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of FOXD4 mRNA | CTD | PMID:30047161 | Foxd4 | Mouse | aflatoxin B1 | decreases methylation | ISO | FOXD4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FOXD4 gene | CTD | PMID:27153756 | Foxd4 | Mouse | amitrole | increases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of FOXD4 mRNA | CTD | PMID:30047161 | Foxd4 | Mouse | ammonium chloride | affects expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of FOXD4 mRNA | CTD | PMID:16483693 | Foxd4 | Mouse | antirheumatic drug | decreases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of FOXD4 mRNA | CTD | PMID:24449571 | Foxd4 | Mouse | aristolochic acid A | increases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of FOXD4 mRNA | CTD | PMID:33212167 | Foxd4 | Mouse | bis(2-chloroethyl) sulfide | increases expression | EXP | | 6480464 | Mustard Gas results in increased expression of FOXD4 mRNA | CTD | PMID:15674843 | Foxd4 | Mouse | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of FOXD4 promoter | CTD | PMID:27334623 | Foxd4 | Mouse | bisphenol A | decreases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of FOXD4L1 mRNA | CTD | PMID:25181051 | Foxd4 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FOXD4 mRNA | CTD | PMID:30951980 | Foxd4 | Mouse | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of FOXD4 mRNA | CTD | PMID:30951980 | Foxd4 | Mouse | calcitriol | increases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of FOXD4 mRNA | CTD | PMID:21592394 | Foxd4 | Mouse | calcitriol | multiple interactions | ISO | FOXD4 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FOXD4 mRNA | CTD | PMID:21592394 | Foxd4 | Mouse | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FOXD4 gene | CTD | PMID:20938992 | Foxd4 | Mouse | cisplatin | multiple interactions | ISO | FOXD4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FOXD4 mRNA | CTD | PMID:27392435 | Foxd4 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FOXD4 gene | CTD | PMID:20938992 | Foxd4 | Mouse | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of FOXD4 mRNA | CTD | PMID:32186404 | Foxd4 | Mouse | indole-3-methanol | affects expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of FOXD4 mRNA | CTD | PMID:21396975 | Foxd4 | Mouse | indole-3-methanol | multiple interactions | ISO | Foxd4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA | CTD | PMID:22129741 | Foxd4 | Mouse | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FOXD4 gene | CTD | PMID:20938992 | Foxd4 | Mouse | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of FOXD4 mRNA | CTD | PMID:22609695 | Foxd4 | Mouse | methimazole | increases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of FOXD4 mRNA | CTD | PMID:30047161 | Foxd4 | Mouse | mono(2-ethylhexyl) phthalate | affects expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate affects the expression of FOXD4 mRNA | CTD | PMID:21195148 | Foxd4 | Mouse | Monobutylphthalate | affects expression | EXP | | 6480464 | monobutyl phthalate affects the expression of FOXD4 mRNA | CTD | PMID:21195148 | Foxd4 | Mouse | N-acetyl-L-cysteine | multiple interactions | ISO | Foxd4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA | CTD | PMID:22129741 | Foxd4 | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Foxd4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA | CTD | PMID:22129741 | Foxd4 | Mouse | rotenone | decreases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of FOXD4 mRNA | CTD | PMID:29955902 | Foxd4 | Mouse | sotorasib | multiple interactions | ISO | FOXD4 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FOXD4 mRNA | CTD | PMID:36139627 | Foxd4 | Mouse | sulfadimethoxine | increases expression | ISO | Foxd4 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of FOXD4 mRNA | CTD | PMID:30047161 | Foxd4 | Mouse | testosterone | multiple interactions | ISO | FOXD4 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FOXD4 mRNA | CTD | PMID:21592394 | Foxd4 | Mouse | testosterone | increases expression | ISO | FOXD4 (Homo sapiens) | 6480464 | Testosterone results in increased expression of FOXD4 mRNA | CTD | PMID:21592394 | Foxd4 | Mouse | Theaflavin 3,3'-digallate | affects expression | ISO | FOXD4 (Homo sapiens) | 6480464 | theaflavin-3 and 3'-digallate affects the expression of FOXD4 mRNA | CTD | PMID:34925699 | Foxd4 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of FOXD4 enhancer and titanium dioxide results in decreased methylation of FOXD4 gene | CTD | PMID:35295148 | Foxd4 | Mouse | trametinib | multiple interactions | ISO | FOXD4 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FOXD4 mRNA | CTD | PMID:36139627 | Foxd4 | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of FOXD4 mRNA | CTD | PMID:33045310 | Foxd4 | Mouse | valproic acid | decreases methylation | ISO | FOXD4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FOXD4 gene | CTD | PMID:29154799 | |