Trpv5 (transient receptor potential cation channel, subfamily V, member 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Trpv5 (transient receptor potential cation channel, subfamily V, member 5) Mus musculus
Analyze
Symbol: Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
RGD ID: 1551251
MGI Page MGI
Description: Exhibits calcium channel activity. Involved in calcium ion homeostasis; calcium ion transmembrane transport; and regulation of urine volume. Localizes to apical plasma membrane and calcium channel complex. Is expressed in central nervous system; metanephros; and sensory organ. Orthologous to human TRPV5 (transient receptor potential cation channel subfamily V member 5); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcium transport protein 2; CaT; CAT2; D630033B11; ECaC; ECAC1; epithelial calcium channel 1; MGC129346; MGC129347; osm-9-like TRP channel 3; OTRPC3; transient receptor potential cation channel subfamily V member 5
RGD Orthologs
Human
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,628,595 - 41,658,158 (-)NCBIGRCm39mm39
GRCm39 Ensembl641,629,107 - 41,657,703 (-)Ensembl
GRCm38641,651,661 - 41,681,224 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,652,173 - 41,680,769 (-)EnsemblGRCm38mm10GRCm38
MGSCv37641,602,769 - 41,630,722 (-)NCBIGRCm37mm9NCBIm37
MGSCv36641,582,737 - 41,610,262 (-)NCBImm8
Celera641,605,358 - 41,633,307 (-)NCBICelera
Cytogenetic Map6B2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12077127   PMID:12205031   PMID:12477932   PMID:12574114   PMID:12660155   PMID:14679186   PMID:15100231   PMID:15123711  
PMID:15355307   PMID:15665527   PMID:15902302   PMID:16141072   PMID:16141073   PMID:16148038   PMID:16239475   PMID:16291808   PMID:16352746   PMID:16354700   PMID:16380433   PMID:16460286  
PMID:16565876   PMID:16602821   PMID:16705151   PMID:17005931   PMID:17012263   PMID:17200157   PMID:17565273   PMID:18597625   PMID:18606998   PMID:19322198   PMID:19470676   PMID:19767875  
PMID:19834762   PMID:19922080   PMID:19965988   PMID:21290301   PMID:21873635   PMID:22266179   PMID:22407925   PMID:23383183   PMID:23466996   PMID:23747339   PMID:24150765   PMID:24434184  
PMID:24557712   PMID:24828496   PMID:26747426   PMID:27102152   PMID:28527294   PMID:30063124   PMID:30786075   PMID:30916584   PMID:32098917   PMID:32325033  


Genomics

Comparative Map Data
Trpv5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,628,595 - 41,658,158 (-)NCBIGRCm39mm39
GRCm39 Ensembl641,629,107 - 41,657,703 (-)Ensembl
GRCm38641,651,661 - 41,681,224 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,652,173 - 41,680,769 (-)EnsemblGRCm38mm10GRCm38
MGSCv37641,602,769 - 41,630,722 (-)NCBIGRCm37mm9NCBIm37
MGSCv36641,582,737 - 41,610,262 (-)NCBImm8
Celera641,605,358 - 41,633,307 (-)NCBICelera
Cytogenetic Map6B2.1NCBI
TRPV5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7142,908,101 - 142,933,746 (-)EnsemblGRCh38hg38GRCh38
GRCh387142,908,101 - 142,933,746 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377142,605,267 - 142,630,843 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,315,770 - 142,340,942 (-)NCBINCBI36hg18NCBI36
Build 347142,122,103 - 142,147,742NCBI
Celera7137,442,506 - 137,467,678 (-)NCBI
Cytogenetic Map7q34NCBI
HuRef7136,943,932 - 136,969,107 (-)NCBIHuRef
CHM1_17142,542,073 - 142,567,695 (-)NCBICHM1_1
CRA_TCAGchr7v27142,007,517 - 142,032,689 (-)NCBI
Trpv5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2470,536,432 - 70,562,743 (-)NCBI
Rnor_6.0 Ensembl470,947,717 - 70,974,006 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0470,947,615 - 70,974,004 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04135,734,774 - 135,761,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,361,051 - 69,387,346 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1469,637,182 - 69,663,476 (-)NCBI
Celera465,501,468 - 65,527,672 (-)NCBICelera
Cytogenetic Map4q23NCBI
TRPV5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,647,070 - 6,678,080 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,650,574 - 6,676,963 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,560,511 - 7,591,662 (+)NCBI
ROS_Cfam_1.0166,557,909 - 6,589,144 (+)NCBI
UMICH_Zoey_3.1166,511,319 - 6,542,465 (+)NCBI
UNSW_CanFamBas_1.0166,362,763 - 6,393,915 (+)NCBI
UU_Cfam_GSD_1.0166,421,480 - 6,452,686 (+)NCBI
Trpv5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511812,503,983 - 12,529,339 (+)NCBI
SpeTri2.0NW_004936527375,922 - 399,446 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPV5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,043,646 - 7,348,381 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,285,186 - 7,341,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,540,598 - 7,549,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRPV5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121111,787,214 - 111,816,893 (-)NCBI
ChlSab1.1 Ensembl21111,787,694 - 111,811,847 (-)Ensembl

Position Markers
Trpv5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38641,652,660 - 41,652,779UniSTSGRCm38
MGSCv37641,602,659 - 41,602,778UniSTSGRCm37
Celera641,605,248 - 41,605,367UniSTS
Cytogenetic Map6B2.1UniSTS
cM Map619.83UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345314181Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348726677Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348726677Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348726677Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707543297169Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797246118070Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122246751334Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122246751334Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61770000053500000Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61773466351734784Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1773466351734784Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61773466351734784Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61963941153639411Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61963941153639411Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61963941153639411Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268671322775Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62007289554072895Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62380000057800000Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2831405962314181Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3172656565726677Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63270000066700000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63389528167895420Mouse
11252142Mom12_mModifier of Min 12 (mouse)63389528167895420Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63629634770296450Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63647147170471591Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3676447870764478Mouse
14746995Manh60_mmandible shape 60 (mouse)63722567771225677Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64089129671379171Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64160000075600000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:516
Count of miRNA genes:322
Interacting mature miRNAs:356
Transcripts:ENSMUST00000031901
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000031901   ⟹   ENSMUSP00000031901
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl641,652,173 - 41,680,769 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193503   ⟹   ENSMUSP00000141421
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl641,653,130 - 41,680,655 (-)Ensembl
RefSeq Acc Id: NM_001007572   ⟹   NP_001007573
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39641,629,704 - 41,657,657 (-)NCBI
GRCm38641,652,770 - 41,680,723 (-)NCBI
MGSCv37641,602,769 - 41,630,722 (-)RGD
Celera641,605,358 - 41,633,307 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505770   ⟹   XP_006505833
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39641,628,595 - 41,656,860 (-)NCBI
GRCm38641,651,661 - 41,679,926 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505771   ⟹   XP_006505834
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39641,628,595 - 41,652,912 (-)NCBI
GRCm38641,651,661 - 41,675,978 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321463   ⟹   XP_017176952
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39641,628,595 - 41,658,052 (-)NCBI
GRCm38641,651,661 - 41,681,118 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321464   ⟹   XP_017176953
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39641,628,595 - 41,658,158 (-)NCBI
GRCm38641,651,661 - 41,681,224 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001007573   ⟸   NM_001007572
- UniProtKB: P69744 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505833   ⟸   XM_006505770
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006505834   ⟸   XM_006505771
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017176953   ⟸   XM_017321464
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017176952   ⟸   XM_017321463
- Peptide Label: isoform X1
- UniProtKB: P69744 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000031901   ⟸   ENSMUST00000031901
RefSeq Acc Id: ENSMUSP00000141421   ⟸   ENSMUST00000193503
Protein Domains
ANK_REP_REGION

Promoters
RGD ID:6889514
Promoter ID:EPDNEW_M8208
Type:single initiation site
Name:Trpv5_1
Description:Mus musculus transient receptor potential cation channel, subfamilyV, member 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38641,680,736 - 41,680,796EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2429764 AgrOrtholog
Ensembl Genes ENSMUSG00000036899 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000031901 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141421 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031901 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000193503 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV5/TRPV6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:194352 UniProtKB/Swiss-Prot
MGD MGI:2429764 ENTREZGENE
NCBI Gene 194352 ENTREZGENE
PANTHER PTHR10582 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trpv5 PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ECACCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ECACCHANNEL2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YW69_MOUSE UniProtKB/TrEMBL
  P69744 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q2TB50 UniProtKB/Swiss-Prot