Gene: TRPV5 (transient receptor potential cation channel subfamily V member 5) Homo sapiens
Symbol: TRPV5
Name: transient receptor potential cation channel subfamily V member 5
Description: This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium transport protein 2; calcium transporter 2; CAT2; ECaC; ECAC1; epithelial calcium channel 1; osm-9-like TRP channel 3; OTRPC3; OTTHUMP00000211572; OTTHUMP00000211602; transient receptor potential cation channel, subfamily V, member 5
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387142,908,101 - 142,933,723 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377142,605,648 - 142,630,820 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,315,770 - 142,340,942 (-)NCBINCBI36hg18NCBI36
Build 347142,122,103 - 142,147,742NCBI
Celera7137,442,506 - 137,467,678 (-)NCBI
Cytogenetic Map7q34NCBI
HuRef7136,943,932 - 136,969,107 (-)NCBIHuRef
CHM1_17142,542,073 - 142,567,695 (-)NCBICHM1_1
CRA_TCAGchr7v27142,007,517 - 142,032,689 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRPV5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350143
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE