Mmp12 (matrix metallopeptidase 12) - Rat Genome Database

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Gene: Mmp12 (matrix metallopeptidase 12) Mus musculus
Analyze
Symbol: Mmp12
Name: matrix metallopeptidase 12
RGD ID: 732694
MGI Page MGI
Description: Predicted to enable several functions, including core promoter sequence-specific DNA binding activity; metal ion binding activity; and metalloendopeptidase activity. Involved in several processes, including protein import into nucleus; regulation of gene expression; and regulation of type I interferon-mediated signaling pathway. Acts upstream of or within bronchiole development and lung alveolus development. Located in extracellular space and nucleus. Is expressed in gonad; large intestine; mesonephros; small intestine; and testis. Human ortholog(s) of this gene implicated in Barrett's esophagus; artery disease (multiple); coronary aneurysm; esophagus adenocarcinoma; and multiple sclerosis. Orthologous to human MMP12 (matrix metallopeptidase 12).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AV378681; macrophage elastase; macrophage metalloelastase; macrophage-metalloelastase; matrix metalloproteinase 12; matrix metalloproteinase-12; MME; Mmel; MMP-12; MMP1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,344,397 - 7,360,461 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl97,344,381 - 7,369,499 (+)EnsemblGRCm39 Ensembl
GRCm3897,344,397 - 7,360,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,344,381 - 7,369,499 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,347,374 - 7,360,461 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3697,347,406 - 7,360,461 (+)NCBIMGSCv36mm8
Celera94,747,651 - 4,760,738 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-lipoic acid  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-nitrophenol  (EXP)
4-nitroquinoline N-oxide  (EXP)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acetohydroxamic acid  (ISO)
acrolein  (ISO)
afimoxifene  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aprepitant  (EXP)
arsenous acid  (ISO)
azathioprine  (ISO)
barium sulfate  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-D-glucosamine  (ISO)
beta-hexachlorocyclohexane  (EXP)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
capsaicin  (EXP)
carbon atom  (ISO)
carbon nanotube  (EXP,ISO)
catechol  (EXP)
cefaloridine  (ISO)
ceric oxide  (EXP,ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (EXP,ISO)
cobalt atom  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
cysteamine  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibenziodolium  (EXP)
diclofenac  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
diquat  (EXP)
diuron  (ISO)
doxorubicin  (EXP,ISO)
elemental carbon  (ISO)
Erionite  (EXP)
ethanol  (EXP)
fenbuconazole  (ISO)
ferric oxide  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (EXP)
furan  (ISO)
genistein  (EXP)
glucose  (EXP)
graphite  (ISO)
indole-3-methanol  (ISO)
L-methionine  (EXP)
lidocaine  (ISO)
linuron  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
LY294002  (EXP,ISO)
malathion  (ISO)
megestrol acetate  (ISO)
metacetamol  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
microcystin-LR  (EXP)
N-acetyl-L-cysteine  (EXP)
N-hydroxyacetimidic acid  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel sulfate  (EXP)
O-methyleugenol  (ISO)
octadecanoic acid  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorodecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
PhIP  (ISO)
pioglitazone  (EXP)
prednisolone  (ISO)
progesterone  (EXP)
quartz  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rottlerin  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium fluoride  (ISO)
sotorasib  (ISO)
succimer  (EXP)
T-2 toxin  (EXP)
tamoxifen  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trametinib  (ISO)
tremolite asbestos  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
Triptolide  (EXP)
triptonide  (EXP)
wortmannin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
extracellular matrix  (IEA)
extracellular region  (IEA,TAS)
extracellular space  (HDA,IBA,IDA,ISO)
nucleus  (IDA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Genetic Loci Modulate Macrophage Activity and Glomerular Damage in Experimental Glomerulonephritis. Behmoaras J, etal., J Am Soc Nephrol. 2010 May 20.
2. Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis. Bradbury PA, etal., Carcinogenesis. 2009 May;30(5):793-8. doi: 10.1093/carcin/bgp065. Epub 2009 Mar 25.
3. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in coxsackievirus-induced myocarditis. Cheung C, etal., Cardiovasc Pathol. 2006 Mar-Apr;15(2):63-74.
4. Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion. Eriksson P, etal., Br J Surg. 2005 Nov;92(11):1372-6.
5. mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas. Hagemann T, etal., Eur J Cancer. 2001 Oct;37(15):1839-46.
6. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome. Ikonomidis JS, etal., Circulation. 2006 Jul 4;114(1 Suppl):I365-70.
7. Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries. Johnson JL, etal., Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15575-80. Epub 2005 Oct 12.
8. Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease. Jormsjo S, etal., Circ Res. 2000 May 12;86(9):998-1003.
9. Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis. Kaneko Y, etal., J Immunol 2003 Mar 15;170(6):3377-85.
10. Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes. Kure M, etal., Mol Genet Metab. 2011 May;103(1):60-5. doi: 10.1016/j.ymgme.2011.01.001. Epub 2011 Jan 14.
11. Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease. Lamblin N, etal., J Am Coll Cardiol. 2002 Jul 3;40(1):43-8.
12. MGDs mouse GO annotations MGD data from the GO Consortium
13. MGD IEA MGD IEA
14. Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population. Mirowska-Guzel D, etal., J Neuroimmunol. 2009 Sep 29;214(1-2):113-7. doi: 10.1016/j.jneuroim.2009.06.014. Epub 2009 Jul 22.
15. Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Morris DG, etal., Nature 2003 Mar 13;422(6928):169-73.
16. Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue. Natarajan G, etal., Alcohol. 2019 Sep;79:71-79. doi: 10.1016/j.alcohol.2018.12.005. Epub 2019 Jan 3.
17. Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation. Okada S, etal., FASEB J. 2008 Oct;22(10):3672-84. doi: 10.1096/fj.08-111872. Epub 2008 Jul 7.
18. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
19. Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome. Rao VH, etal., Am J Pathol. 2006 Jul;169(1):32-46.
20. Mouse MP Annotation Import Pipeline RGD automated import pipeline
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Spleen tyrosine kinase promotes acute neutrophil-mediated glomerular injury via activation of JNK and p38 MAPK in rat nephrotoxic serum nephritis. Ryan J, etal., Lab Invest. 2011 Dec;91(12):1727-38. doi: 10.1038/labinvest.2011.137. Epub 2011 Sep 5.
23. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
24. Up-regulation and coexpression of MIF and matrix metalloproteinases in human abdominal aortic aneurysms. Verschuren L, etal., Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1195-202.
25. Matrix metalloproteinase (MMP)-12 expression has a negative impact on sensorimotor function following intracerebral haemorrhage in mice. Wells JE, etal., Eur J Neurosci. 2005 Jan;21(1):187-96.
26. Polymorphisms in matrix metalloproteinase-1, -3, -9, and -12 genes in relation to subarachnoid hemorrhage. Zhang B, etal., Stroke. 2001 Sep;32(9):2198-202.
Additional References at PubMed
PMID:1431103   PMID:1537850   PMID:1931076   PMID:7558021   PMID:7559635   PMID:8188294   PMID:8226919   PMID:8632994   PMID:9302297   PMID:9344654   PMID:9398846   PMID:10187779  
PMID:10349636   PMID:10502816   PMID:10760605   PMID:10841523   PMID:10949577   PMID:11042159   PMID:11076861   PMID:11113146   PMID:11217851   PMID:11395391   PMID:11502863   PMID:11689884  
PMID:12097550   PMID:12189240   PMID:12204900   PMID:12477932   PMID:12815621   PMID:12842850   PMID:12858542   PMID:14602826   PMID:14633606   PMID:14751561   PMID:14993123   PMID:15063736  
PMID:15342725   PMID:15452344   PMID:15489334   PMID:15579436   PMID:15618213   PMID:15734845   PMID:15800495   PMID:15814723   PMID:15983040   PMID:16081501   PMID:16141072   PMID:16141073  
PMID:16236725   PMID:16495447   PMID:16500946   PMID:16571779   PMID:16778188   PMID:16912171   PMID:17136358   PMID:17209037   PMID:17395890   PMID:17446527   PMID:17620183   PMID:17681721  
PMID:18003950   PMID:18203142   PMID:18441096   PMID:18479957   PMID:18547653   PMID:18660381   PMID:18806126   PMID:18852254   PMID:18997394   PMID:19218336   PMID:19221044   PMID:19346698  
PMID:19513084   PMID:19536155   PMID:19620042   PMID:19672072   PMID:19935767   PMID:20093499   PMID:20101093   PMID:20181883   PMID:20651245   PMID:21212406   PMID:21267068   PMID:21321074  
PMID:21378275   PMID:21719762   PMID:21784967   PMID:21814804   PMID:21856305   PMID:21873635   PMID:21944884   PMID:22014525   PMID:22119538   PMID:22153340   PMID:22171010   PMID:22223197  
PMID:22773692   PMID:23061826   PMID:23159549   PMID:23271741   PMID:23285156   PMID:23295969   PMID:23421805   PMID:23813962   PMID:23922714   PMID:23978445   PMID:24006456   PMID:24526442  
PMID:24784232   PMID:24828142   PMID:24907602   PMID:24914890   PMID:24914938   PMID:25166912   PMID:25211233   PMID:25302498   PMID:25310974   PMID:25503990   PMID:25636537   PMID:25652021  
PMID:25686691   PMID:25797678   PMID:25864931   PMID:26079807   PMID:26438797   PMID:26445891   PMID:26563237   PMID:26608672   PMID:26676790   PMID:26822129   PMID:27015453   PMID:27306493  
PMID:27383629   PMID:27398409   PMID:27862656   PMID:28237967   PMID:28442300   PMID:28814604   PMID:29429629   PMID:29503085   PMID:29523595   PMID:29550371   PMID:29722565   PMID:29925830  
PMID:30294471   PMID:30510003   PMID:30753170   PMID:30880028   PMID:30959793   PMID:31009606   PMID:31399604   PMID:31562139   PMID:32242260   PMID:32295421   PMID:32693803   PMID:32855420  
PMID:32882513   PMID:32987131   PMID:33072094   PMID:34622152   PMID:34653936   PMID:34681679   PMID:34703996   PMID:35031603   PMID:35382832   PMID:35493520   PMID:35657352   PMID:35759974  
PMID:36252818   PMID:36691905   PMID:37312667   PMID:37701782   PMID:37816293   PMID:38017481   PMID:38355793   PMID:38542140  


Genomics

Comparative Map Data
Mmp12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,344,397 - 7,360,461 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl97,344,381 - 7,369,499 (+)EnsemblGRCm39 Ensembl
GRCm3897,344,397 - 7,360,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,344,381 - 7,369,499 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,347,374 - 7,360,461 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3697,347,406 - 7,360,461 (+)NCBIMGSCv36mm8
Celera94,747,651 - 4,760,738 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
MMP12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,862,736 - 102,874,982 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11102,862,736 - 102,874,982 (-)EnsemblGRCh38hg38GRCh38
GRCh3711102,733,467 - 102,745,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,238,674 - 102,250,922 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411102,238,685 - 102,250,889NCBI
Celera1199,895,056 - 99,907,358 (-)NCBICelera
Cytogenetic Map11q22.2NCBI
HuRef1198,661,485 - 98,673,788 (-)NCBIHuRef
CHM1_111102,616,439 - 102,628,740 (-)NCBICHM1_1
T2T-CHM13v2.011102,866,505 - 102,878,751 (-)NCBIT2T-CHM13v2.0
Mmp12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8812,866,652 - 12,876,554 (+)NCBIGRCr8
mRatBN7.284,581,785 - 4,591,687 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,581,785 - 4,599,611 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,541,507 - 8,551,408 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.086,839,275 - 6,849,176 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.084,841,439 - 4,851,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,594,717 - 5,616,494 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,606,592 - 5,616,493 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,610,392 - 5,620,294 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,249,938 - 4,259,675 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.184,249,937 - 4,259,675 (+)NCBI
Celera86,141,589 - 6,151,491 (+)NCBICelera
Cytogenetic Map8q11NCBI
Mmp12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554126,045,100 - 6,057,262 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554126,045,146 - 6,057,112 (-)NCBIChiLan1.0ChiLan1.0
MMP12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,662,554 - 103,674,969 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,750,772 - 104,763,148 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,809,644 - 97,822,063 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,294,469 - 101,306,762 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,294,475 - 101,306,762 (-)Ensemblpanpan1.1panPan2
MMP12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1528,918,626 - 28,933,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl528,918,594 - 28,933,309 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha528,867,153 - 28,881,802 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0528,944,813 - 28,984,612 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl528,969,618 - 28,984,462 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1529,004,848 - 29,019,524 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0528,884,303 - 28,898,943 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0529,059,239 - 29,073,925 (+)NCBIUU_Cfam_GSD_1.0
Mmp12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,418,317 - 86,430,234 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365515,106,285 - 5,117,843 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365515,107,567 - 5,117,843 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,473,093 - 33,483,679 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1933,473,625 - 33,483,630 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,421,192 - 37,431,173 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,243,061 - 94,261,035 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,243,875 - 94,259,591 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604331,622,735 - 31,635,226 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248786,035 - 17,445 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248786,017 - 17,368 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mmp12
451 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1549
Count of miRNA genes:671
Interacting mature miRNAs:872
Transcripts:ENSMUST00000005950, ENSMUST00000065079, ENSMUST00000120655, ENSMUST00000127722, ENSMUST00000138220, ENSMUST00000148005, ENSMUST00000150167
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse

Markers in Region
M82831  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3897,358,346 - 7,358,458UniSTSGRCm38
MGSCv3797,358,346 - 7,358,458UniSTSGRCm37
Celera94,758,623 - 4,758,735UniSTS
Cytogenetic Map9A1UniSTS
cM Map91.0UniSTS
Whitehead/MRC_RH995.58UniSTS
px-35d2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8D3UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map8B1.2UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map9A1UniSTS
cM Map1354.0UniSTS
cM Map91.1UniSTS
cM Map91.0UniSTS
px-72g5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7CUniSTS
Cytogenetic Map3H2UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map12B1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map8B1.2UniSTS
Cytogenetic Map9A1UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map3BUniSTS
cM Map1354.0UniSTS
cM Map91.0UniSTS
cM Map316.4UniSTS
px-24g4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7CUniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map3H2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map3F2.3UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map12B1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map9A1UniSTS
Cytogenetic Map17E2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map17CUniSTS
cM Map91.0UniSTS
cM Map316.4UniSTS
cM Map1740.0UniSTS
cM Map1354.0UniSTS
Mmp12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3897,348,715 - 7,350,095UniSTSGRCm38
MGSCv3797,348,715 - 7,350,095UniSTSGRCm37
Celera94,748,992 - 4,750,372UniSTS
Cytogenetic Map9A1UniSTS
cM Map91.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001320076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC169512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY622972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY195619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY539785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M82831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000005950   ⟹   ENSMUSP00000005950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,347,374 - 7,360,461 (+)Ensembl
GRCm38.p6 Ensembl97,347,374 - 7,360,461 (+)Ensembl
Ensembl Acc Id: ENSMUST00000065079   ⟹   ENSMUSP00000065291
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,347,374 - 7,369,499 (+)Ensembl
GRCm38.p6 Ensembl97,347,374 - 7,369,499 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120655   ⟹   ENSMUSP00000114129
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,344,397 - 7,358,464 (+)Ensembl
GRCm38.p6 Ensembl97,344,397 - 7,358,464 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127722   ⟹   ENSMUSP00000120225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,347,406 - 7,358,888 (+)Ensembl
GRCm38.p6 Ensembl97,347,406 - 7,358,888 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138220
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,347,406 - 7,348,333 (+)Ensembl
GRCm38.p6 Ensembl97,347,406 - 7,348,333 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,347,406 - 7,357,663 (+)Ensembl
GRCm38.p6 Ensembl97,347,406 - 7,357,663 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150167   ⟹   ENSMUSP00000116080
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl97,344,381 - 7,349,787 (+)Ensembl
GRCm38.p6 Ensembl97,344,381 - 7,349,787 (+)Ensembl
RefSeq Acc Id: NM_001320076   ⟹   NP_001307005
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3997,347,374 - 7,360,461 (+)NCBI
GRCm3897,347,374 - 7,360,461 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001320077   ⟹   NP_001307006
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3997,344,397 - 7,360,461 (+)NCBI
GRCm3897,344,397 - 7,360,461 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008605   ⟹   NP_032631
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3997,347,374 - 7,360,461 (+)NCBI
GRCm3897,347,374 - 7,360,461 (+)NCBI
MGSCv3797,347,374 - 7,360,461 (+)RGD
Celera94,747,651 - 4,760,738 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017313160   ⟹   XP_017168649
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3997,346,259 - 7,358,683 (+)NCBI
GRCm3897,346,257 - 7,358,683 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001307005 (Get FASTA)   NCBI Sequence Viewer  
  NP_001307006 (Get FASTA)   NCBI Sequence Viewer  
  NP_032631 (Get FASTA)   NCBI Sequence Viewer  
  XP_017168649 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA39526 (Get FASTA)   NCBI Sequence Viewer  
  AAH19135 (Get FASTA)   NCBI Sequence Viewer  
  AAT46403 (Get FASTA)   NCBI Sequence Viewer  
  BAC40832 (Get FASTA)   NCBI Sequence Viewer  
  BAC40836 (Get FASTA)   NCBI Sequence Viewer  
  BAC40846 (Get FASTA)   NCBI Sequence Viewer  
  BAC40889 (Get FASTA)   NCBI Sequence Viewer  
  BAC40909 (Get FASTA)   NCBI Sequence Viewer  
  BAC40913 (Get FASTA)   NCBI Sequence Viewer  
  BAC41067 (Get FASTA)   NCBI Sequence Viewer  
  BAE29689 (Get FASTA)   NCBI Sequence Viewer  
  BAE30039 (Get FASTA)   NCBI Sequence Viewer  
  BAE30260 (Get FASTA)   NCBI Sequence Viewer  
  BAE30809 (Get FASTA)   NCBI Sequence Viewer  
  BAE33072 (Get FASTA)   NCBI Sequence Viewer  
  BAE33411 (Get FASTA)   NCBI Sequence Viewer  
  BAE33414 (Get FASTA)   NCBI Sequence Viewer  
  BAE33415 (Get FASTA)   NCBI Sequence Viewer  
  BAE33469 (Get FASTA)   NCBI Sequence Viewer  
  BAE41743 (Get FASTA)   NCBI Sequence Viewer  
  BAE41746 (Get FASTA)   NCBI Sequence Viewer  
  BAE41839 (Get FASTA)   NCBI Sequence Viewer  
  BAE42035 (Get FASTA)   NCBI Sequence Viewer  
  BAE42039 (Get FASTA)   NCBI Sequence Viewer  
  BAE42154 (Get FASTA)   NCBI Sequence Viewer  
  BAE42177 (Get FASTA)   NCBI Sequence Viewer  
  BAE42198 (Get FASTA)   NCBI Sequence Viewer  
  BAE42201 (Get FASTA)   NCBI Sequence Viewer  
  BAE42294 (Get FASTA)   NCBI Sequence Viewer  
  BAE42446 (Get FASTA)   NCBI Sequence Viewer  
  BAE42457 (Get FASTA)   NCBI Sequence Viewer  
  BAE42458 (Get FASTA)   NCBI Sequence Viewer  
  BAE42459 (Get FASTA)   NCBI Sequence Viewer  
  BAE42460 (Get FASTA)   NCBI Sequence Viewer  
  BAE42472 (Get FASTA)   NCBI Sequence Viewer  
  BAE42474 (Get FASTA)   NCBI Sequence Viewer  
  BAE42476 (Get FASTA)   NCBI Sequence Viewer  
  BAE42478 (Get FASTA)   NCBI Sequence Viewer  
  BAE42486 (Get FASTA)   NCBI Sequence Viewer  
  BAE42502 (Get FASTA)   NCBI Sequence Viewer  
  BAE42516 (Get FASTA)   NCBI Sequence Viewer  
  BAE42531 (Get FASTA)   NCBI Sequence Viewer  
  CAJ18584 (Get FASTA)   NCBI Sequence Viewer  
  EDL24933 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000005950
  ENSMUSP00000005950.6
  ENSMUSP00000065291.6
  ENSMUSP00000114129
  ENSMUSP00000114129.2
  ENSMUSP00000116080.2
  ENSMUSP00000120225.2
GenBank Protein P34960 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032631   ⟸   NM_008605
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q8BJB9 (UniProtKB/Swiss-Prot),   Q8BJB8 (UniProtKB/Swiss-Prot),   Q8BJB6 (UniProtKB/Swiss-Prot),   Q8BJB3 (UniProtKB/Swiss-Prot),   Q8BJ92 (UniProtKB/Swiss-Prot),   Q4FJM7 (UniProtKB/Swiss-Prot),   Q3UBC5 (UniProtKB/Swiss-Prot),   Q3U2R8 (UniProtKB/Swiss-Prot),   Q3U1S9 (UniProtKB/Swiss-Prot),   Q3U1S8 (UniProtKB/Swiss-Prot),   Q3TD61 (UniProtKB/Swiss-Prot),   Q3TBV9 (UniProtKB/Swiss-Prot),   Q3TBV6 (UniProtKB/Swiss-Prot),   Q3TB28 (UniProtKB/Swiss-Prot),   Q8VED6 (UniProtKB/Swiss-Prot),   P34960 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001307006   ⟸   NM_001320077
- Peptide Label: isoform 3
- UniProtKB: Q3TCW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168649   ⟸   XM_017313160
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001307005   ⟸   NM_001320076
- Peptide Label: isoform 2
- UniProtKB: P34960 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000116080   ⟸   ENSMUST00000150167
Ensembl Acc Id: ENSMUSP00000065291   ⟸   ENSMUST00000065079
Ensembl Acc Id: ENSMUSP00000120225   ⟸   ENSMUST00000127722
Ensembl Acc Id: ENSMUSP00000114129   ⟸   ENSMUST00000120655
Ensembl Acc Id: ENSMUSP00000005950   ⟸   ENSMUST00000005950
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P34960-F1-model_v2 AlphaFold P34960 1-473 view protein structure

Promoters
RGD ID:6844805
Promoter ID:MM_KWN:56321
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:NM_008605,   OTTMUST00000067721,   OTTMUST00000067722,   OTTMUST00000067736,   UC009OCJ.1,   UC009OCM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3697,347,246 - 7,347,746 (+)MPROMDB
RGD ID:8668746
Promoter ID:EPDNEW_M12404
Type:multiple initiation site
Name:Mmp12_1
Description:Mus musculus matrix metallopeptidase 12 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3897,347,406 - 7,347,466EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97005 AgrOrtholog
Ensembl Genes ENSMUSG00000049723 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000005950 ENTREZGENE
  ENSMUST00000005950.12 UniProtKB/Swiss-Prot
  ENSMUST00000065079.6 UniProtKB/TrEMBL
  ENSMUST00000120655 ENTREZGENE
  ENSMUST00000120655.8 UniProtKB/TrEMBL
  ENSMUST00000127722.2 UniProtKB/TrEMBL
  ENSMUST00000150167.2 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M10A_MMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17381 UniProtKB/Swiss-Prot
MGD MGI:97005 ENTREZGENE
NCBI Gene 17381 ENTREZGENE
PANTHER MACROPHAGE METALLOELASTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mmp12 PhenoGen
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOPEXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART SM00120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47090 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z705_MOUSE UniProtKB/TrEMBL
  D6RJI9_MOUSE UniProtKB/TrEMBL
  MMP12_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TB28 ENTREZGENE
  Q3TBV6 ENTREZGENE
  Q3TBV9 ENTREZGENE
  Q3TCW6 ENTREZGENE, UniProtKB/TrEMBL
  Q3TD61 ENTREZGENE
  Q3U1S8 ENTREZGENE
  Q3U1S9 ENTREZGENE
  Q3U2R8 ENTREZGENE
  Q3UBC5 ENTREZGENE
  Q4FJM7 ENTREZGENE
  Q6GX99_MOUSE UniProtKB/TrEMBL
  Q8BJ92 ENTREZGENE
  Q8BJB3 ENTREZGENE
  Q8BJB6 ENTREZGENE
  Q8BJB8 ENTREZGENE
  Q8BJB9 ENTREZGENE
  Q8BJC0_MOUSE UniProtKB/TrEMBL
  Q8VED6 ENTREZGENE
UniProt Secondary Q3TB28 UniProtKB/Swiss-Prot
  Q3TBV6 UniProtKB/Swiss-Prot
  Q3TBV9 UniProtKB/Swiss-Prot
  Q3TD61 UniProtKB/Swiss-Prot
  Q3U1S8 UniProtKB/Swiss-Prot
  Q3U1S9 UniProtKB/Swiss-Prot
  Q3U2R8 UniProtKB/Swiss-Prot
  Q3UBC5 UniProtKB/Swiss-Prot
  Q4FJM7 UniProtKB/Swiss-Prot
  Q8BJ92 UniProtKB/Swiss-Prot
  Q8BJB3 UniProtKB/Swiss-Prot
  Q8BJB6 UniProtKB/Swiss-Prot
  Q8BJB8 UniProtKB/Swiss-Prot
  Q8BJB9 UniProtKB/Swiss-Prot
  Q8VED6 UniProtKB/Swiss-Prot