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Gene: Ddx58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58) Mus musculus
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Symbol: Ddx58
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Description: Exhibits double-stranded DNA binding activity; double-stranded RNA binding activity; and single-stranded RNA binding activity. Involved in several processes, including positive regulation of cytokine production; response to exogenous dsRNA; and response to virus. Predicted to localize to several cellular components, including the actin cytoskeleton; bicellular tight junction; and ruffle membrane. Is expressed in alimentary system; olfactory epithelium; ovary; and renal calyx. Orthologous to human DDX58 (DExD/H-box helicase 58); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6430573D20Rik; C330021E21; DEAD box protein 58; DEAD-box protein 58; DEAD/H box polypeptide RIG-I; probable ATP-dependent RNA helicase DDX58; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIG-I; RIG-I-like receptor 1; RLR-1
Orthologs:
Homo sapiens (human) : DDX58 (DExD/H-box helicase 58)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddx58 (DEXD/H-box helicase 58)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx58 (DExD/H-box helicase 58)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX58 (DExD/H-box helicase 58)
Canis lupus familiaris (dog) : DDX58 (DExD/H-box helicase 58)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx58 (DExD/H-box helicase 58)
Sus scrofa (pig) : DDX58 (DExD/H-box helicase 58)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38440,203,777 - 40,239,825 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37440,150,810 - 40,186,858 (-)NCBIGRCm37mm9NCBIm37
MGSCv36440,394,461 - 40,428,372 (-)NCBImm8
Celera439,866,998 - 39,902,804 (-)NCBICelera
Cytogenetic Map4 A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ddx58
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319813
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.