Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ddx58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58) Mus musculus
Symbol: Ddx58
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Description: Exhibits double-stranded DNA binding activity; double-stranded RNA binding activity; and single-stranded RNA binding activity. Involved in several processes, including positive regulation of cytokine production; response to exogenous dsRNA; and response to virus. Predicted to localize to several cellular components, including the actin cytoskeleton; bicellular tight junction; and ruffle membrane. Is expressed in alimentary system; olfactory epithelium; ovary; and renal calyx. Orthologous to human DDX58 (DExD/H-box helicase 58); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6430573D20Rik; C330021E21; DEAD box protein 58; DEAD-box protein 58; DEAD/H box polypeptide RIG-I; probable ATP-dependent RNA helicase DDX58; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIG-I; RIG-I-like receptor 1; RLR-1
Homo sapiens (human) : DDX58 (DExD/H-box helicase 58)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddx58 (DEXD/H-box helicase 58)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx58 (DExD/H-box helicase 58)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX58 (DExD/H-box helicase 58)
Canis lupus familiaris (dog) : DDX58 (DExD/H-box helicase 58)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx58 (DExD/H-box helicase 58)
Sus scrofa (pig) : DDX58 (DExD/H-box helicase 58)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38440,203,777 - 40,239,825 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37440,150,810 - 40,186,858 (-)NCBIGRCm37mm9NCBIm37
MGSCv36440,394,461 - 40,428,372 (-)NCBImm8
Celera439,866,998 - 39,902,804 (-)NCBICelera
Cytogenetic Map4 A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ddx58
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319813
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.