Il1rn (interleukin 1 receptor antagonist) - Rat Genome Database

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Gene: Il1rn (interleukin 1 receptor antagonist) Mus musculus
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Symbol: Il1rn
Name: interleukin 1 receptor antagonist
RGD ID: 733437
MGI Page MGI
Description: Predicted to have cytokine receptor binding activity. Involved in insulin secretion and lipid metabolic process. Localizes to extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: F630041P17Rik; IL; IL-1ra; IL-1RN; IL1 inhibitor; interleukin-1 receptor antagonist protein; IRAP
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,226,872 - 24,241,503 (+)NCBIGRCm39mm39
GRCm39 Ensembl224,226,865 - 24,241,506 (+)Ensembl
GRCm38224,336,860 - 24,351,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,336,853 - 24,351,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,192,380 - 24,207,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36224,158,869 - 24,173,490 (+)NCBImm8
Celera224,056,294 - 24,070,923 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Abscess  (ISO)
acute kidney failure  (IDA,ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
Acute Necrotizing Pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
allergic conjunctivitis  (ISO)
alopecia areata  (ISO)
Anorexia  (ISO)
anterior uveitis  (ISO)
anthracosis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
Arsenic Poisoning  (ISO)
asthma  (ISO)
Atrophy  (ISO)
autistic disorder  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
autosomal dominant polycystic kidney disease  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (IMP)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiolitis  (ISO)
bronchiolitis obliterans  (ISO)
Bronchopulmonary Dysplasia  (ISO)
bronchus carcinoma  (ISO)
Cachexia  (ISO)
calcium oxalate nephrolithiasis  (ISO)
cardiovascular system disease  (ISO)
Carotid Artery Injuries  (ISO)
Cerebral Hemorrhage  (ISO)
cerebrovascular disease  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Rhinosinusitis  (ISO)
Chronic Uveitis  (ISO)
cicatricial pemphigoid  (ISO)
Colonic Neoplasms  (ISO)
common cold  (ISO)
Corneal Graft Rejection  (ISO)
corneal neovascularization  (IMP,ISO)
COVID-19  (ISO)
crescentic glomerulonephritis  (ISO)
Cryopyrin-Associated Periodic Syndromes  (ISO)
cystic fibrosis  (ISO)
dacryocystitis  (ISO)
Deficiency of Interleukin-1 Receptor Antagonist  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diarrhea  (ISO)
Drug Hypersensitivity Syndrome  (ISO)
Drug-Induced Agranulocytosis  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (ISO)
encephalitis  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Endotoxin-Induced Uveitis  (IMP,ISO)
exanthem  (ISO)
Experimental Arthritis  (IMP,ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Myocarditis  (IMP)
Experimental Autoimmune Uveitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (IDA,IMP,ISO)
Extravasation of Diagnostic and Therapeutic Materials  (ISO)
Eye Manifestations  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
fibromyalgia  (ISO)
Fibrosis  (ISO)
glomerulonephritis  (IEP,ISO)
gout  (ISO)
Graft vs Host Disease  (ISO)
Graves Ophthalmopathy  (ISO)
hairy cell leukemia  (ISO)
hemolytic-uremic syndrome  (ISO)
Henoch-Schoenlein purpura  (ISO)
hepatocellular carcinoma  (ISO)
hereditary diffuse gastric cancer  (ISO)
herpes simplex virus keratitis  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
hypertension  (ISO)
idiopathic pulmonary fibrosis  (ISO)
IgA glomerulonephritis  (IMP,ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
interstitial lung disease  (ISO)
juvenile rheumatoid arthritis  (ISO)
keratoconus  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (IMP,ISO)
learning disability  (ISO)
Leukocytosis  (ISO)
Lichen Sclerosus et Atrophicus  (ISO)
listeriosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Mammary Neoplasms, Experimental  (ISO)
Meibomian Gland Dysfunction  (ISO)
melanoma  (ISO)
mental depression  (ISO)
middle cerebral artery infarction  (ISO)
morbid obesity  (ISO)
Muckle-Wells syndrome  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
myositis  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
nephrotic syndrome  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (IAGP,ISO)
Oligoanuria  (ISO)
osteoporosis  (ISO)
Pain  (ISO)
periodontitis  (ISO)
pleural disease  (ISO)
pleural tuberculosis  (ISO)
pleurisy  (ISO)
pneumonia  (IEP,ISO)
Postoperative Cognitive Dysfunction  (ISO)
pre-eclampsia  (ISO)
Proctocolitis  (ISO)
Prostatic Neoplasms  (ISO)
prostatitis  (IEP)
proteinuria  (ISO)
Pseudomonas Aeruginosa Keratitis  (IDA,IEP)
Pseudomonas Infections  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pyelonephritis  (ISO)
renal cell carcinoma  (ISO)
respiratory allergy  (IMP)
rheumatoid arthritis  (IMP,ISO)
rhinitis  (ISO)
Schnitzler syndrome  (ISO)
sciatic neuropathy  (ISO)
Sclerosis  (ISO)
Sepsis  (IEP,ISO)
Serositis  (ISO)
silicosis  (ISO)
Sjogren's syndrome  (ISO)
skin disease  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (ISO)
Tobacco Use Disorder  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (IMP,ISO)
urinary bladder cancer  (ISO)
Urinary Calculi  (ISO)
Uveitis, Chronic Anterior  (ISO)
vascular disease  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
Viral Bronchiolitis  (ISO)
viral pneumonia  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3',5'-cyclic AMP  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3,7-dihydropurine-6-thione  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (EXP)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (EXP)
7-ketocholesterol  (ISO)
acetamide  (ISO)
acetylcholine  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
aldehydo-D-glucose  (ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinyl palmitate  (ISO)
alpha-naphthoflavone  (ISO)
aluminium hydroxide  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
beclomethasone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
carvedilol  (ISO)
celastrol  (ISO)
ceric oxide  (ISO)
cholesterol  (ISO)
choline  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
delta-tocotrienol  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloroacetic acid  (EXP)
dichloromethane  (EXP)
diclofenac  (EXP,ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP)
folic acid  (EXP)
fumonisin B1  (EXP)
gedunin  (ISO)
Genipin  (EXP)
genistein  (EXP)
glafenine  (ISO)
glucose  (ISO)
glycidol  (ISO)
graphene oxide  (EXP)
graphite  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
isoliquiritigenin  (EXP)
isoprenaline  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
leflunomide  (ISO)
lenalidomide  (EXP)
lipopolysaccharide  (EXP,ISO)
malonaldehyde  (ISO)
manganese(II) chloride  (ISO)
mercaptopurine  (ISO)
mercury dichloride  (ISO)
metformin  (EXP)
methacholine chloride  (EXP,ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methyltestosterone  (ISO)
Mofezolac (TN)  (ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (EXP,ISO)
nicotine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
paricalcitol  (ISO)
pentane-2,3-dione  (ISO)
perfluorooctanoic acid  (EXP)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium dichromate  (EXP)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
prostaglandin E2  (ISO)
purine-6-thiol  (ISO)
quercetin  (EXP)
resveratrol  (ISO)
rofecoxib  (ISO)
rotenone  (EXP)
scopolamine  (EXP)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
Soman  (EXP)
streptozocin  (EXP)
succimer  (EXP)
sulfasalazine  (ISO)
tacrolimus hydrate  (EXP)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP)
thalidomide  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
tremolite asbestos  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (EXP)
trimethyltin  (EXP)
urethane  (ISO)
wortmannin  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta elastic tissue morphology  (IAGP)
abnormal body temperature homeostasis  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal dendritic cell differentiation  (IAGP)
abnormal dendritic cell number  (IAGP)
abnormal dermal layer morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal macrophage chemotaxis  (IAGP)
abnormal T-helper 1 cell morphology  (IAGP)
abnormal T-helper 2 cell morphology  (IAGP)
abnormal vascular wound healing  (IAGP)
aneurysm  (IAGP)
aortitis  (IAGP)
artery stenosis  (IAGP)
chronic inflammation  (IAGP)
decreased body weight  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating interleukin-1 level  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
epidermal desquamation  (IAGP)
granulomatous inflammation  (IAGP)
increased acute inflammation  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating serum amyloid protein level  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased interleukin-17 secretion  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to induced arthritis  (IAGP)
increased T cell proliferation  (IAGP)
parakeratosis  (IAGP)
pathological neovascularization  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
psoriasis  (IAGP)
reduced fertility  (IAGP)
rheumatoid arthritis  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
thick dermal layer  (IAGP)
thick epidermis  (IAGP)
References

References - curated
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Additional References at PubMed
PMID:1358808   PMID:1828262   PMID:1830498   PMID:1834470   PMID:2137200   PMID:2137201   PMID:7850809   PMID:7989596   PMID:8003626   PMID:8100556   PMID:8176222   PMID:8216424  
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PMID:16081819   PMID:16129814   PMID:16141072   PMID:16141073   PMID:16306368   PMID:16320323   PMID:16374779   PMID:16385385   PMID:16415102   PMID:16569679   PMID:16602821   PMID:16622029  
PMID:16622035   PMID:17021861   PMID:17283139   PMID:17429444   PMID:17823985   PMID:17942936   PMID:17967442   PMID:17982084   PMID:18060042   PMID:18279308   PMID:18282478   PMID:18594791  
PMID:18606706   PMID:19002106   PMID:19144317   PMID:19213834   PMID:19261929   PMID:19458323   PMID:19559408   PMID:19571816   PMID:19656856   PMID:19922413   PMID:20110570   PMID:20112392  
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PMID:22942082   PMID:22980031   PMID:23209411   PMID:23308180   PMID:23396662   PMID:23475218   PMID:23671185   PMID:23689131   PMID:23840826   PMID:23845567   PMID:24431229   PMID:24558360  
PMID:24566623   PMID:24603878   PMID:25156255   PMID:25209981   PMID:25244011   PMID:25479427   PMID:25725107   PMID:25839897   PMID:25909959   PMID:26002078   PMID:26042735   PMID:26108163  
PMID:26209680   PMID:26276675   PMID:26413013   PMID:26474296   PMID:26661518   PMID:26873573   PMID:26951334   PMID:26972847   PMID:27109611   PMID:27476761   PMID:27480124   PMID:27482635  
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PMID:31611644   PMID:31745167   PMID:31932497   PMID:31972159   PMID:32471111   PMID:33064141  


Genomics

Comparative Map Data
Il1rn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,226,872 - 24,241,503 (+)NCBIGRCm39mm39
GRCm39 Ensembl224,226,865 - 24,241,506 (+)Ensembl
GRCm38224,336,860 - 24,351,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,336,853 - 24,351,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,192,380 - 24,207,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36224,158,869 - 24,173,490 (+)NCBImm8
Celera224,056,294 - 24,070,923 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.36NCBI
IL1RN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2113,107,214 - 113,134,016 (+)EnsemblGRCh38hg38GRCh38
GRCh382113,099,365 - 113,134,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,875,548 - 113,891,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,591,941 - 113,608,064 (+)NCBINCBI36hg18NCBI36
Build 342113,591,700 - 113,607,823NCBI
Celera2107,260,159 - 107,276,191 (+)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,329,950 - 106,345,897 (+)NCBIHuRef
CHM1_12113,879,899 - 113,896,017 (+)NCBICHM1_1
Il1rn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.237,111,567 - 7,127,451 (+)NCBI
Rnor_6.0 Ensembl31,452,644 - 1,468,614 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.031,449,778 - 1,468,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.031,445,598 - 1,461,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.432,607,800 - 2,613,216 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.132,607,803 - 2,611,842 (+)NCBI
Celera31,959,290 - 1,964,693 (+)NCBICelera
Cytogenetic Map3p13NCBI
Il1rn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,144,810 - 1,159,471 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,145,022 - 1,159,413 (-)NCBIChiLan1.0ChiLan1.0
LOC100991079
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A114,061,182 - 114,077,048 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A114,061,182 - 114,078,839 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A88,991,646 - 89,008,013 (-)NCBIMhudiblu_PPA_v0panPan3
IL1RN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,236,690 - 37,250,424 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,212,751 - 37,249,329 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1737,014,575 - 37,019,617 (+)NCBI
ROS_Cfam_1.01738,014,380 - 38,028,164 (+)NCBI
UMICH_Zoey_3.11737,157,832 - 37,162,873 (+)NCBI
UNSW_CanFamBas_1.01737,214,332 - 37,219,374 (+)NCBI
UU_Cfam_GSD_1.01737,426,795 - 37,431,843 (+)NCBI
Il1rn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,552,650 - 82,571,860 (+)NCBI
SpeTri2.0NW_0049367831,447,158 - 1,466,331 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RN
(Sus scrofa - pig)
No map positions available.
IL1RN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11416,136,667 - 16,152,451 (+)NCBI
ChlSab1.1 Ensembl1416,146,333 - 16,151,326 (+)Ensembl
Il1rn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474913,210,365 - 13,224,471 (+)NCBI

Position Markers
M64404  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38224,349,891 - 24,350,030UniSTSGRCm38
MGSCv37224,205,411 - 24,205,550UniSTSGRCm37
Celera224,069,325 - 24,069,464UniSTS
Cytogenetic Map2A3UniSTS
cM Map210.0UniSTS
Whitehead/MRC_RH2412.23UniSTS
UniSTS:224661  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38224,349,764 - 24,349,925UniSTSGRCm38
MGSCv37224,205,284 - 24,205,445UniSTSGRCm37
Celera224,069,198 - 24,069,359UniSTS
Cytogenetic Map2A3UniSTS
cM Map210.0UniSTS
Il1rn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38224,350,674 - 24,350,851UniSTSGRCm38
MGSCv37224,206,194 - 24,206,371UniSTSGRCm37
Celera224,070,108 - 24,070,283UniSTS
Cytogenetic Map2A3UniSTS
cM Map210.0UniSTS
Il1rn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38224,349,640 - 24,350,396UniSTSGRCm38
MGSCv37224,205,160 - 24,205,916UniSTSGRCm37
Celera224,069,074 - 24,069,830UniSTS
Cytogenetic Map2A3UniSTS
cM Map210.0UniSTS
Il1rn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
cM Map210.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142333Tgq10_mtriglyceride QTL 10 (mouse)Not determined125319748Mouse
4141836Tgq11_mtriglyceride QTL 11 (mouse)Not determined125319748Mouse
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126524778Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323390328289138Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2778910341789249Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2834628442346384Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2841803942418228Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2949443443494563Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2949443443494563Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967188027132630Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212472666726109Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21432455548324701Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2123971355239859Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22123971355239859Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22379913357799257Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1406
Count of miRNA genes:572
Interacting mature miRNAs:660
Transcripts:ENSMUST00000114482, ENSMUST00000114485, ENSMUST00000114486, ENSMUST00000114487, ENSMUST00000142093, ENSMUST00000143423
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF001795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY206809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ383807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ383808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI656439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M57525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M74294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S64082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000114482   ⟹   ENSMUSP00000110126
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,345,310 - 24,350,936 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114485   ⟹   ENSMUSP00000110129
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,345,288 - 24,349,807 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114486
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,336,856 - 24,339,409 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114487   ⟹   ENSMUSP00000110131
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,336,853 - 24,351,494 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142093   ⟹   ENSMUSP00000141269
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,336,856 - 24,349,457 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143423
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl224,345,348 - 24,346,354 (+)Ensembl
RefSeq Acc Id: NM_001039701   ⟹   NP_001034790
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39224,235,383 - 24,241,503 (+)NCBI
GRCm38224,345,371 - 24,351,491 (+)NCBI
MGSCv37224,192,380 - 24,207,011 (+)RGD
Celera224,056,294 - 24,070,923 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159562   ⟹   NP_001153034
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39224,235,303 - 24,241,503 (+)NCBI
GRCm38224,345,291 - 24,351,491 (+)NCBI
MGSCv37224,192,380 - 24,207,011 (+)RGD
Celera224,056,294 - 24,070,923 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_031167   ⟹   NP_112444
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39224,226,872 - 24,241,503 (+)NCBI
GRCm38224,336,860 - 24,351,491 (+)ENTREZGENE
MGSCv37224,192,380 - 24,207,011 (+)RGD
Celera224,056,294 - 24,070,923 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497727   ⟹   XP_006497790
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39224,235,126 - 24,241,497 (+)NCBI
GRCm38224,345,111 - 24,351,485 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034790 (Get FASTA)   NCBI Sequence Viewer  
  NP_001153034 (Get FASTA)   NCBI Sequence Viewer  
  NP_112444 (Get FASTA)   NCBI Sequence Viewer  
  XP_006497790 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA20576 (Get FASTA)   NCBI Sequence Viewer  
  AAA39277 (Get FASTA)   NCBI Sequence Viewer  
  AAA39278 (Get FASTA)   NCBI Sequence Viewer  
  AAA39309 (Get FASTA)   NCBI Sequence Viewer  
  AAA39310 (Get FASTA)   NCBI Sequence Viewer  
  AAB20265 (Get FASTA)   NCBI Sequence Viewer  
  AAC15251 (Get FASTA)   NCBI Sequence Viewer  
  AAH42532 (Get FASTA)   NCBI Sequence Viewer  
  ABD43196 (Get FASTA)   NCBI Sequence Viewer  
  ABD43197 (Get FASTA)   NCBI Sequence Viewer  
  ABD43198 (Get FASTA)   NCBI Sequence Viewer  
  ABD43199 (Get FASTA)   NCBI Sequence Viewer  
  BAC36291 (Get FASTA)   NCBI Sequence Viewer  
  BAC40797 (Get FASTA)   NCBI Sequence Viewer  
  BAE32704 (Get FASTA)   NCBI Sequence Viewer  
  BAE33152 (Get FASTA)   NCBI Sequence Viewer  
  BAE33361 (Get FASTA)   NCBI Sequence Viewer  
  BAE33421 (Get FASTA)   NCBI Sequence Viewer  
  BAE33438 (Get FASTA)   NCBI Sequence Viewer  
  BAE33460 (Get FASTA)   NCBI Sequence Viewer  
  BAE33484 (Get FASTA)   NCBI Sequence Viewer  
  BAE33497 (Get FASTA)   NCBI Sequence Viewer  
  BAE33984 (Get FASTA)   NCBI Sequence Viewer  
  BAE41757 (Get FASTA)   NCBI Sequence Viewer  
  BAE42202 (Get FASTA)   NCBI Sequence Viewer  
  BAE42426 (Get FASTA)   NCBI Sequence Viewer  
  CBY45190 (Get FASTA)   NCBI Sequence Viewer  
  EDL08170 (Get FASTA)   NCBI Sequence Viewer  
  P25085 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_112444   ⟸   NM_031167
- Peptide Label: isoform 1
- UniProtKB: P25085 (UniProtKB/Swiss-Prot),   Q542W1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001034790   ⟸   NM_001039701
- Peptide Label: isoform 2 precursor
- UniProtKB: P25085 (UniProtKB/Swiss-Prot),   Q542C7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001153034   ⟸   NM_001159562
- Peptide Label: isoform 3
- UniProtKB: Q3TBV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497790   ⟸   XM_006497727
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000110131   ⟸   ENSMUST00000114487
RefSeq Acc Id: ENSMUSP00000110129   ⟸   ENSMUST00000114485
RefSeq Acc Id: ENSMUSP00000110126   ⟸   ENSMUST00000114482
RefSeq Acc Id: ENSMUSP00000141269   ⟸   ENSMUST00000142093

Promoters
RGD ID:6831617
Promoter ID:MM_KWN:28037
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:OTTMUST00000028283,   OTTMUST00000028286
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36224,192,234 - 24,192,734 (+)MPROMDB
RGD ID:6831616
Promoter ID:MM_KWN:28038
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:ENSMUST00000114486
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36224,192,951 - 24,193,667 (+)MPROMDB
RGD ID:6831618
Promoter ID:MM_KWN:28039
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   MEF_B6
Transcripts:ENSMUST00000114482,   OTTMUST00000028287,   OTTMUST00000028288
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36224,200,416 - 24,201,022 (+)MPROMDB
RGD ID:6876514
Promoter ID:EPDNEW_M1707
Type:initiation region
Name:Il1rn_1
Description:Mus musculus interleukin 1 receptor antagonist , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38224,345,417 - 24,345,477EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96547 AgrOrtholog
Ensembl Genes ENSMUSG00000026981 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000110126 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110129 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000110131 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141269 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000114482 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114485 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000114487 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000142093 UniProtKB/TrEMBL
InterPro IL-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1RA/IL-36 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1RA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16181 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96547 ENTREZGENE
NCBI Gene 16181 ENTREZGENE
PANTHER PTHR10078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10078:SF28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il1rn PhenoGen
PRINTS INTERLEUKIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKIN1X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YVU4_MOUSE UniProtKB/TrEMBL
  IL1RA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TBV5 ENTREZGENE, UniProtKB/TrEMBL
  Q542C7 ENTREZGENE, UniProtKB/TrEMBL
  Q542W1 ENTREZGENE, UniProtKB/TrEMBL
  Q8CGA1_MOUSE UniProtKB/TrEMBL
UniProt Secondary O70207 UniProtKB/Swiss-Prot