Il13 (interleukin 13) - Rat Genome Database

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Gene: Il13 (interleukin 13) Mus musculus
Analyze
Symbol: Il13
Name: interleukin 13
RGD ID: 69009
MGI Page MGI
Description: Predicted to enable interleukin-13 receptor binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of macrophage activation. Acts upstream of or within cellular response to cytokine stimulus; inflammatory response; and positive regulation of immune effector process. Located in cytoplasm; external side of plasma membrane; and extracellular space. Is expressed in gut; liver; male reproductive gland or organ; and thymus. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Il-; Il-13; interleukin-13; T-cell activation protein P600
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,522,150 - 53,525,529 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,522,151 - 53,525,529 (-)EnsemblGRCm39 Ensembl
GRCm381153,631,323 - 53,634,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,631,324 - 53,634,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,444,825 - 53,448,204 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,474,747 - 53,478,125 (-)NCBIMGSCv36mm8
Celera1158,210,849 - 58,214,228 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
alcoholic hepatitis  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
asthma  (IDA,IEP,IMP,ISO)
atopic dermatitis  (IEP,IMP,ISO)
autistic disorder  (ISO)
autoimmune hepatitis  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (IDA,IMP,ISO)
bronchiolitis obliterans  (IMP,ISO)
chlamydia  (IMP)
Chronic Bronchitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
contact dermatitis  (IDA)
COVID-19  (ISO)
cutaneous leishmaniasis  (IEP)
cystic fibrosis  (ISO)
Delayed Hypersensitivity  (IDA)
dermatitis  (ISO)
diffuse scleroderma  (ISO)
drug allergy  (ISO)
Eczema  (ISO)
egg allergy  (ISO)
Endotoxemia  (ISO)
esophagitis  (IMP)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (IMP,ISO)
Experimental Autoimmune Myocarditis  (ISO)
extrinsic allergic alveolitis  (IEP,ISO)
familial adenomatous polyposis 1  (ISO)
Fibrosis  (ISO)
food allergy  (IEP)
Fungal Lung Diseases  (IEP,ISO)
genetic disease  (ISO)
Graves' disease  (ISO)
hepatitis C  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
Hyperplasia  (ISO)
Immediate Hypersensitivity  (ISO)
Inflammation  (ISO)
invasive ductal carcinoma  (ISO)
Kawasaki disease  (IDA)
lipoid nephrosis  (ISO)
localized scleroderma  (ISO)
lung disease  (IMP,ISO)
Lymphatic Metastasis  (ISO)
mastocytosis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Metaplasia  (ISO)
middle cerebral artery infarction  (ISO)
milk allergy  (ISO)
multiple sclerosis  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
Nasal Polyps  (ISO)
Neurodevelopmental Disorders  (ISO)
occupational dermatitis  (IMP)
onchocerciasis  (ISO)
ovarian carcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
peanut allergy  (ISO)
peptic esophagitis  (ISO)
Perennial Allergic Rhinitis  (ISO)
Picornaviridae Infections  (IEP)
Plasmodium falciparum malaria  (ISO)
pneumonia  (ISO)
prostatic hypertrophy  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (IMP)
pulmonary eosinophilia  (IMP)
pulmonary fibrosis  (IEP,IMP,ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
purpura  (ISO)
Radiation Pneumonitis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (IEP,ISO)
Respiratory Sounds  (ISO)
respiratory syncytial virus infectious disease  (IMP)
Respiratory Tract Granuloma  (IMP)
Respiratory Tract Infections  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (IMP,ISO)
Schistosomiasis Mansoni  (ISO)
Sepsis  (IMP,ISO)
sinusitis  (ISO)
Sjogren's syndrome  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (IEP,ISO)
T-cell non-Hodgkin lymphoma  (IMP)
Transplant Rejection  (ISO)
uveitis  (ISO)
vitiligo  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (EXP)
(R,R,R)-alpha-tocopherol  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,4-naphthoquinone  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-tert-butylhydroquinone  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-tolyl isocyanate  (EXP)
9-cis-retinoic acid  (ISO)
abacavir  (ISO)
acetone  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-galactosylceramide  (EXP)
aluminium hydroxide  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antigen  (EXP,ISO)
apigenin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
beclomethasone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzofurans  (EXP)
benzyl isothiocyanate  (ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brevetoxin B  (ISO)
Brevianamide A  (EXP)
bucladesine  (ISO)
budesonide  (ISO)
butanal  (ISO)
butane-2,3-dione  (EXP)
C.I. Natural Red 20  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
Calcimycin  (EXP,ISO)
calcipotriol  (EXP)
calcitriol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (ISO)
capsaicin  (ISO)
carbon monoxide  (EXP)
carbon nanotube  (EXP,ISO)
carveol  (EXP)
ceric oxide  (EXP)
chlorobenzene  (ISO)
chloroform  (EXP)
chloroquine  (EXP)
chlorpyrifos  (ISO)
choline  (EXP)
clopidogrel  (EXP)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP)
D-penicillamine  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dichlorine  (EXP)
dicyclohexylmethane-4,4'-diisocyanate  (EXP)
diisononyl phthalate  (EXP)
dioscin  (EXP)
diphenylmethane-4,4'-diisocyanate  (EXP)
donepezil hydrochloride  (EXP)
emamectin benzoate  (ISO)
emodin  (EXP)
epinastine  (ISO)
etazolate  (ISO)
ethambutol  (ISO)
ethene  (ISO)
ferric oxide  (EXP)
Fidarestat  (EXP,ISO)
fisetin  (ISO)
formaldehyde  (EXP,ISO)
formoterol fumarate  (ISO)
fragrance  (ISO)
Fulvic acid  (ISO)
gadodiamide hydrate  (ISO)
gadolinium trichloride  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glutathione  (ISO)
glyphosate  (EXP)
gossypin  (ISO)
graphite  (EXP)
hexamethylene diisocyanate  (EXP)
hydrogen peroxide  (ISO)
hydroxysafflor yellow A  (EXP)
hydroxyurea  (EXP)
ilomastat  (ISO)
ionomycin  (EXP)
isophorone diisocyanate  (EXP)
lactacystin  (EXP)
lead diacetate  (EXP)
lead(0)  (EXP)
leflunomide  (ISO)
leukotriene B4  (ISO)
leukotriene C4  (EXP,ISO)
leukotriene D4  (ISO)
leukotriene E4  (ISO)
lidocaine  (EXP)
linuron  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (EXP)
lorcaserin  (EXP)
luteolin  (ISO)
malathion  (ISO)
melatonin  (EXP)
mercury atom  (EXP)
mercury dichloride  (EXP)
mercury(0)  (EXP)
metformin  (EXP)
methotrexate  (EXP,ISO)
methoxychlor  (EXP,ISO)
MK 571  (EXP,ISO)
montelukast  (EXP)
morphine  (EXP)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N-acetyl-L-cysteine  (ISO)
N-ethyl-5'-carboxamidoadenosine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
naproxen  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP)
nitrogen dioxide  (EXP,ISO)
nitrososulfamethoxazole  (ISO)
ochratoxin A  (ISO)
organophosphorus compound  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
parathion  (EXP)
patulin  (ISO)
phenobarbital  (ISO)
phentermine  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosmet  (ISO)
phthalaldehyde  (EXP)
phthalic anhydride  (EXP,ISO)
Phytolaccoside E  (ISO)
pioglitazone  (EXP)
piperonyl butoxide  (EXP)
polymyxin B2  (EXP)
pomalidomide  (ISO)
prednisolone  (EXP)
prednisone  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prostaglandin E2  (ISO)
pyocyanine  (EXP)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rolipram  (ISO)
ruxolitinib  (ISO)
SB-239063  (EXP)
serotonin  (EXP)
serpentine asbestos  (EXP)
Shikonin  (EXP)
silicon dioxide  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sterigmatocystin  (EXP)
sulfur dioxide  (EXP)
sumatriptan  (ISO)
sunitinib  (ISO)
syringin  (EXP)
Terfenadine  (ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
TMC-120A  (EXP)
toluene 2,4-diisocyanate  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
Triptolide  (EXP)
valproic acid  (ISO)
vitamin E  (EXP)
wogonin  (EXP)
zearalenone  (ISO)
zileuton  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to cytokine stimulus  (IDA)
cellular response to mechanical stimulus  (ISO)
immune response  (IEA)
inflammatory response  (IMP)
macrophage activation  (ISO)
microglial cell activation  (ISO)
negative regulation of complement-dependent cytotoxicity  (ISO)
negative regulation of endothelial cell apoptotic process  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of NAD(P)H oxidase activity  (ISO)
negative regulation of transforming growth factor beta production  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of cold-induced thermogenesis  (IMP)
positive regulation of connective tissue growth factor production  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of immunoglobulin production  (IGI,IMP,ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of macrophage activation  (IMP)
positive regulation of mast cell degranulation  (IGI,IMP)
positive regulation of monoatomic ion transport  (ISO)
positive regulation of pancreatic stellate cell proliferation  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of release of sequestered calcium ion into cytosol  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
regulation of proton transport  (ISO)
response to ethanol  (ISO)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to nicotine  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal antigen presentation  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal chemokine level  (IAGP)
abnormal dendritic cell antigen presentation  (IAGP)
abnormal dendritic cell differentiation  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal interleukin secretion  (IAGP)
abnormal interleukin-4 secretion  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal leukocyte physiology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal response to injury  (IAGP)
abnormal response to transplant  (IAGP)
abnormal splenocyte physiology  (IAGP)
abnormal susceptibility to infection  (IAGP)
abnormal T-helper 2 cell differentiation  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
abnormal type I hypersensitivity reaction  (IAGP)
decreased circulating interleukin-13 level  (IAGP)
decreased core body temperature  (IAGP)
decreased eosinophil cell number  (IAGP)
decreased fatty acids level  (IAGP)
decreased IgE level  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased inflammatory response  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-10 secretion  (IAGP)
decreased interleukin-13 secretion  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased interleukin-5 secretion  (IAGP)
decreased interleukin-9 secretion  (IAGP)
decreased macrophage cell number  (IAGP)
decreased noradrenaline level  (IAGP)
decreased skeletal muscle weight  (IAGP)
decreased susceptibility to autoimmune disorder  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to injury  (IAGP)
decreased susceptibility to parasitic infection  (IAGP)
decreased susceptibility to parasitic infection induced morbidity/mortality  (IAGP)
decreased T-helper 2 cell number  (IAGP)
granulomatous inflammation  (IAGP)
ileum inflammation  (IAGP)
impaired eosinophil recruitment  (IAGP)
impaired neutrophil recruitment  (IAGP)
increased circulating HDL cholesterol level  (IEA)
increased eosinophil cell number  (IAGP)
increased IgG2a level  (IAGP)
increased IgG2b level  (IAGP)
increased IgM level  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased length of allograft survival  (IAGP)
increased pulmonary ventilation  (IEA)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to parasitic infection induced morbidity/mortality  (IAGP)
increased susceptibility to type I hypersensitivity reaction  (IAGP)
increased susceptibility to weight loss  (IAGP)
pulmonary fibrosis  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Akbari O, etal., Nat Med. 2003 May;9(5):582-8. Epub 2003 Mar 31.
2. Effects of allergic airway disease on mouse adenovirus type 1 respiratory infection. Anderson VE, etal., Virology. 2009 Aug 15;391(1):25-32. Epub 2009 Jun 28.
3. Cytokine production, activation marker, and skin homing receptor in children with atopic dermatitis and bronchial asthma. Antunez C, etal., Pediatr Allergy Immunol. 2006 May;17(3):166-74.
4. Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood. Arshad SH, etal., Br J Dermatol. 2008 Jun;158(6):1315-22. doi: 10.1111/j.1365-2133.2008.08565.x. Epub 2008 Apr 10.
5. Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development. Aspord C, etal., J Exp Med. 2007 May 14;204(5):1037-47. Epub 2007 Apr 16.
6. Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts. Asquith KL, etal., PLoS Pathog. 2011 May;7(5):e1001339. Epub 2011 May 5.
7. Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria. Ayimba E, etal., Clin Exp Immunol. 2011 Nov;166(2):218-26. doi: 10.1111/j.1365-2249.2011.04474.x.
8. Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma. Battle NC, etal., Am J Respir Crit Care Med. 2007 May 1;175(9):881-7. Epub 2007 Feb 15.
9. Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease. Beghe B, etal., Allergy. 2010 Apr;65(4):474-81. Epub 2009 Oct 1.
10. Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza. Bermejo-Martin JF, etal., Crit Care. 2009;13(6):R201. Epub 2009 Dec 11.
11. Increased hyperoxia-induced mortality and acute lung injury in IL-13 null mice. Bhandari V, etal., J Immunol. 2007 Apr 15;178(8):4993-5000.
12. Pharmacological assessment of the nitric-oxide synthase isoform involved in eosinophilic inflammation in a rat model of sephadex-induced airway inflammation. Birrell MA, etal., J Pharmacol Exp Ther. 2003 Mar;304(3):1285-91.
13. Interleukin 13 and interleukin 4 receptor-alpha polymorphisms in rhinitis and asthma. Bottema RW, etal., Int Arch Allergy Immunol. 2010;153(3):259-67. Epub 2010 May 19.
14. Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris. Bowes J, etal., Ann Rheum Dis. 2011 Jun;70(6):1016-9. doi: 10.1136/ard.2010.143123. Epub 2011 Feb 23.
15. Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression. Broen JC, etal., J Rheumatol. 2012 Jan;39(1):112-8. doi: 10.3899/jrheum.110235. Epub 2011 Nov 1.
16. Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF-alpha and IL-6 and augmentation of IL-10 and IL-13. Cao YZ, etal., Exp Toxicol Pathol. 2012 Sep;64(6):543-7. doi: 10.1016/j.etp.2010.11.011. Epub 2010 Dec 14.
17. Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. Cash E, etal., J Immunol. 1994 Nov 1;153(9):4258-67.
18. IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease. Castilow EM, etal., J Immunol. 2008 Feb 15;180(4):2376-84.
19. Interleukin-13 and IgE production in rat experimental schistosomiasis. Cetre C, etal., Eur Cytokine Netw. 2000 Jun;11(2):241-49.
20. Association between non-atopic hand eczema and interleukin-13 gene polymorphism in Taiwanese nursing population. Chen YC, etal., Exp Dermatol. 2012 Dec;21(12):972-4. doi: 10.1111/exd.12045.
21. Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension. Christmann RB, etal., Arthritis Rheum. 2011 Jun;63(6):1718-28. doi: 10.1002/art.30318.
22. Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury. Cortijo J, etal., Br J Pharmacol. 2009 Feb;156(3):534-44.
23. IL-13 prolongs allograft survival: association with inhibition of macrophage cytokine activation. Davidson C, etal., Transpl Immunol. 2007 Apr;17(3):178-86. Epub 2006 Nov 3.
24. Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13. de Kozak Y, etal., Am J Pathol. 2007 Apr;170(4):1241-57.
25. IL-13 from Th2-type cells suppresses induction of antigen-specific Th1 immunity in a T-cell lymphoma. Deepak P, etal., Int Immunol. 2010 Jan;22(1):53-63. doi: 10.1093/intimm/dxp114. Epub 2009 Nov 30.
26. [Association of interleukin-13 gene polymorphisms with atopic bronchial asthma] Dmitrieva-Zdorova EV, etal., Genetika. 2010 Jan;46(1):111-7.
27. Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking. Duffin KC, etal., J Invest Dermatol. 2009 Dec;129(12):2777-83. doi: 10.1038/jid.2009.169. Epub 2009 Jun 25.
28. Ultrastructural and immunological features of experimental cutaneous leishmaniasis after treatment with intralesional hypertonic sodium chloride and CO2 laser rays. Eissa MM, etal., J Egypt Soc Parasitol. 2003 Apr;33(1):329-52.
29. The effect of hydrodynamics-based delivery of an IL-13-Ig fusion gene for experimental autoimmune myocarditis in rats and its possible mechanism. Elnaggar R, etal., Eur J Immunol. 2005 Jun;35(6):1995-2005.
30. Interleukin13 haplotypes and susceptibility of Iranian women to breast cancer. Faghih Z, etal., Mol Biol Rep. 2009 Sep;36(7):1923-8. doi: 10.1007/s11033-008-9400-7. Epub 2008 Nov 7.
31. Genetic variants of the genes encoding zinc finger protein 313 and interleukin-13 confer a risk for psoriasis in a Chinese Uygur population. Feng YY, etal., Clin Exp Dermatol. 2013 Oct;38(7):768-74. Epub 2013 Mar 21.
32. T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice. Forbes E, etal., Gastroenterology. 2004 Jul;127(1):105-18.
33. Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases. Formentini A, etal., Int J Colorectal Dis. 2009 Jan;24(1):57-67. Epub 2008 Aug 31.
34. Spatial and temporal expression of CCR3 and the common beta chain of the IL-3, IL-5 and GM-CSF receptor in the nasal epithelium and lymphoid tissues in a rat model of allergic rhinitis. Fortin M, etal., Cytokine. 2010 Aug 7.
35. Characterization of cytokine mRNA transcripts in conjunctival cells in patients with allergic conjunctivitis. Fujishima H, etal., Invest Ophthalmol Vis Sci. 1997 Jun;38(7):1350-7.
36. Interleukin-13 promoter gene polymorphism -1112 C/T is associated with atopic dermatitis in Polish patients. Glen J, etal., Acta Dermatovenerol Croat. 2012 Dec;20(4):231-8.
37. Phenotypic and functional changes of cytotoxic CD56pos natural T cells determine outcome of acute hepatitis C virus infection. Golden-Mason L, etal., J Virol. 2007 Sep;81(17):9292-8. doi: 10.1128/JVI.00834-07. Epub 2007 Jun 6.
38. Enhanced allergic inflammation and airway responsiveness in rats with chronic Cryptococcus neoformans infection: potential role for fungal pulmonary infection in the pathogenesis of asthma. Goldman DL, etal., J Infect Dis. 2006 Apr 15;193(8):1178-86. Epub 2006 Mar 9.
39. Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Gourh P, etal., Arthritis Res Ther. 2009;11(5):R147. Epub 2009 Oct 2.
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PMID:21552267   PMID:21602491   PMID:21616524   PMID:21628656   PMID:21638273   PMID:21722219   PMID:21826890   PMID:21915293   PMID:21924496   PMID:22039015   PMID:22054060   PMID:22079492  
PMID:22101429   PMID:22138715   PMID:22210911   PMID:22245215   PMID:22246861   PMID:22539286   PMID:22546005   PMID:22684943   PMID:22686327   PMID:22761864   PMID:22763407   PMID:22829596  
PMID:22930549   PMID:23006545   PMID:23027612   PMID:23124025   PMID:23125252   PMID:23131786   PMID:23166721   PMID:23184931   PMID:23190881   PMID:23213461   PMID:23241885   PMID:23248269  
PMID:23257358   PMID:23275605   PMID:23335246   PMID:23351078   PMID:23382928   PMID:23392704   PMID:23420878   PMID:23453702   PMID:23470628   PMID:23509346   PMID:23509358   PMID:23564227  
PMID:23659714   PMID:23667909   PMID:23683462   PMID:23716700   PMID:23784081   PMID:23810766   PMID:23954132   PMID:23972995   PMID:23982586   PMID:24015275   PMID:24037376   PMID:24166975  
PMID:24194600   PMID:24280725   PMID:24336249   PMID:24344271   PMID:24363163   PMID:24368564   PMID:24403255   PMID:24556597   PMID:24565845   PMID:24583134   PMID:24631157   PMID:24634488  
PMID:24663677   PMID:24781052   PMID:24837103   PMID:24892809   PMID:24906148   PMID:24970469   PMID:24979482   PMID:25010390   PMID:25015831   PMID:25029349   PMID:25091976   PMID:25092334  
PMID:25116623   PMID:25172162   PMID:25211233   PMID:25323825   PMID:25336167   PMID:25400503   PMID:25404305   PMID:25450368   PMID:25466256   PMID:25493691   PMID:25546547   PMID:25648335  
PMID:25751266   PMID:25772331   PMID:25779634   PMID:25921340   PMID:25944087   PMID:25981357   PMID:26044350   PMID:26079807   PMID:26088754   PMID:26092469   PMID:26110994   PMID:26132778  
PMID:26160172   PMID:26189367   PMID:26192556   PMID:26196745   PMID:26299987   PMID:26335962   PMID:26361334   PMID:26423151   PMID:26436920   PMID:26456931   PMID:26481668   PMID:26523376  
PMID:26523868   PMID:26555705   PMID:26560039   PMID:26675736   PMID:26688514   PMID:26690703   PMID:26750312   PMID:26809113   PMID:26896776   PMID:26900854   PMID:26992046   PMID:27049059  
PMID:27117406   PMID:27125685   PMID:27156176   PMID:27177780   PMID:27215490   PMID:27240831   PMID:27256220   PMID:27273006   PMID:27357235   PMID:27417023   PMID:27421703   PMID:27479084  
PMID:27492144   PMID:27626380   PMID:27629921   PMID:27653694   PMID:27659424   PMID:27679954   PMID:27697499   PMID:27742702   PMID:27745702   PMID:27749840   PMID:27815425   PMID:27865862  
PMID:27994070   PMID:28004808   PMID:28011865   PMID:28096407   PMID:28196875   PMID:28202615   PMID:28228256   PMID:28302646   PMID:28359899   PMID:28375154   PMID:28392332   PMID:28406139  
PMID:28420758   PMID:28431248   PMID:28490634   PMID:28506464   PMID:28514653   PMID:28589929   PMID:28600286   PMID:28694386   PMID:28704401   PMID:28775096   PMID:28801358   PMID:28869965  
PMID:28893952   PMID:28969943   PMID:28982074   PMID:28982732   PMID:29045902   PMID:29045903   PMID:29225050   PMID:29305434   PMID:29374027   PMID:29392836   PMID:29463471   PMID:29496881  
PMID:29569714   PMID:29688375   PMID:29782549   PMID:29887373   PMID:29935165   PMID:29972778   PMID:30021144   PMID:30201992   PMID:30209189   PMID:30291029   PMID:30339498   PMID:30514570  
PMID:30530480   PMID:30555475   PMID:30575775   PMID:30586758   PMID:30600200   PMID:30755607   PMID:30779711   PMID:31126996   PMID:31128962   PMID:31144294   PMID:31235256   PMID:31248899  
PMID:31296924   PMID:31371561   PMID:31505056   PMID:31534167   PMID:31582416   PMID:31776260   PMID:31825972   PMID:31924686   PMID:31974500   PMID:32031571   PMID:32096290   PMID:32130902  
PMID:32160525   PMID:32240850   PMID:32276028   PMID:32327706   PMID:32355002   PMID:32641386   PMID:32721946   PMID:32846954   PMID:32917785   PMID:32948777   PMID:33020569   PMID:33086036  
PMID:33305354   PMID:33328477   PMID:33397719   PMID:33400692   PMID:33529171   PMID:33536623   PMID:33547321   PMID:33852849   PMID:33929099   PMID:34127548   PMID:34185704   PMID:34194428  
PMID:34196299   PMID:34290377   PMID:34293404   PMID:34498703   PMID:34587523   PMID:34650552   PMID:34789557   PMID:34795444   PMID:34815787   PMID:35060690   PMID:35245089   PMID:35260535  
PMID:35303432   PMID:35359977   PMID:36018297   PMID:36044899   PMID:36414210   PMID:36639371   PMID:36948193   PMID:36982747   PMID:36995338   PMID:37224625   PMID:37285842   PMID:37380774  
PMID:37676935   PMID:38030609  


Genomics

Comparative Map Data
Il13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,522,150 - 53,525,529 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,522,151 - 53,525,529 (-)EnsemblGRCm39 Ensembl
GRCm381153,631,323 - 53,634,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,631,324 - 53,634,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,444,825 - 53,448,204 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,474,747 - 53,478,125 (-)NCBIMGSCv36mm8
Celera1158,210,849 - 58,214,228 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
IL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,656,522 - 132,661,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,656,263 - 132,661,110 (+)EnsemblGRCh38hg38GRCh38
GRCh375131,992,214 - 131,996,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,021,764 - 132,024,700 (+)NCBINCBI36Build 36hg18NCBI36
Build 345132,021,763 - 132,024,700NCBI
Celera5128,123,995 - 128,126,931 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,186,169 - 127,189,105 (+)NCBIHuRef
CHM1_15131,427,162 - 131,430,098 (+)NCBICHM1_1
T2T-CHM13v2.05133,176,323 - 133,180,911 (+)NCBIT2T-CHM13v2.0
Il13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,290,926 - 38,293,483 (-)NCBIGRCr8
mRatBN7.21037,790,130 - 37,792,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,790,130 - 37,792,737 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1042,482,076 - 42,484,637 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,972,140 - 41,974,701 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,475,862 - 37,478,423 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,982,909 - 38,985,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,982,909 - 38,985,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,764,639 - 38,767,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,093,512 - 39,096,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11039,102,758 - 39,105,316 (-)NCBI
Celera1037,134,342 - 37,136,897 (-)NCBICelera
Cytogenetic Map10q22NCBI
Il13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,046,406 - 4,049,795 (+)NCBIChiLan1.0ChiLan1.0
IL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24127,968,733 - 127,973,681 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,108,155 - 126,113,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,073,863 - 128,078,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,235,788 - 134,240,548 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,235,788 - 134,240,548 (+)Ensemblpanpan1.1panPan2
IL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,957,870 - 20,961,391 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,958,464 - 20,961,388 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,759,917 - 19,762,847 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01121,744,389 - 21,747,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,744,389 - 21,747,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,462,871 - 20,465,798 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,310,464 - 20,313,371 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,952,917 - 20,955,847 (+)NCBIUU_Cfam_GSD_1.0
Il13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,527,018 - 115,529,671 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,530,491 - 2,532,373 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,529,933 - 2,532,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,972,623 - 134,975,093 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,972,099 - 134,976,672 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,441,025 - 140,444,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,475,762 - 35,479,419 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,476,490 - 35,478,869 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603442,463,847 - 42,466,277 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,428,095 - 39,429,843 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473339,427,189 - 39,430,019 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il13
108 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:318
Count of miRNA genes:229
Interacting mature miRNAs:256
Transcripts:ENSMUST00000020650
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
4141770Tcpm1_mT-cell phenotype modifier 1 (mouse)Not determined5145247953615930Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse

Markers in Region
M23504  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,631,958 - 53,632,065UniSTSGRCm38
MGSCv371153,445,460 - 53,445,567UniSTSGRCm37
Celera1158,211,484 - 58,211,591UniSTS
Cytogenetic Map11B1.3UniSTS
Whitehead/MRC_RH11727.02UniSTS
Il13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,632,194 - 53,632,440UniSTSGRCm38
MGSCv371153,445,696 - 53,445,942UniSTSGRCm37
Celera1158,211,720 - 58,211,966UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1129.0UniSTS
Il13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020650   ⟹   ENSMUSP00000020650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,522,151 - 53,525,529 (-)Ensembl
GRCm38.p6 Ensembl1153,631,324 - 53,634,702 (-)Ensembl
RefSeq Acc Id: NM_008355   ⟹   NP_032381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,522,150 - 53,525,529 (-)NCBI
GRCm381153,631,323 - 53,634,702 (-)ENTREZGENE
MGSCv371153,444,825 - 53,448,204 (-)RGD
Celera1158,210,849 - 58,214,228 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40149 (Get FASTA)   NCBI Sequence Viewer  
  EDL33575 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020650
  ENSMUSP00000020650.2
GenBank Protein P20109 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032381   ⟸   NM_008355
- Peptide Label: precursor
- UniProtKB: P20109 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020650   ⟸   ENSMUST00000020650

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P20109-F1-model_v2 AlphaFold P20109 1-131 view protein structure

Promoters
RGD ID:8674620
Promoter ID:EPDNEW_M15341
Type:multiple initiation site
Name:Il13_1
Description:Mus musculus interleukin 13 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,634,700 - 53,634,760EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96541 AgrOrtholog
Ensembl Genes ENSMUSG00000020383 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020650 ENTREZGENE
  ENSMUST00000020650.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot
  IL-13 UniProtKB/Swiss-Prot
  IL-4/IL-13 UniProtKB/Swiss-Prot
  IL-4/IL-13_CS UniProtKB/Swiss-Prot
KEGG Report mmu:16163 UniProtKB/Swiss-Prot
MGD MGI:96541 ENTREZGENE
NCBI Gene 16163 ENTREZGENE
Pfam IL13 UniProtKB/Swiss-Prot
PharmGKB IL13 RGD
PhenoGen Il13 PhenoGen
PRINTS INTRLEUKIN13 UniProtKB/Swiss-Prot
PROSITE INTERLEUKIN_4_13 UniProtKB/Swiss-Prot
SMART IL4_13 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot
UniProt IL13_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE