Gk (glycerol kinase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Gk (glycerol kinase) Mus musculus
Analyze
Symbol: Gk
Name: glycerol kinase
RGD ID: 737445
MGI Page MGI
Description: Enables glycerol kinase activity. Involved in triglyceride biosynthetic process. Acts upstream of or within glucose homeostasis; glycerol metabolic process; and regulation of fatty acid metabolic process. Located in mitochondrion. Is active in cytosol. Is expressed in several structures, including brain; brown fat; genitourinary system; liver; and spleen. Used to study glycerol kinase deficiency. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP:glycerol 3-phosphotransferase; D930012N15Rik; glycerokinase; Gyk
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X84,745,543 - 84,820,425 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX84,745,543 - 84,820,425 (-)EnsemblGRCm39 Ensembl
GRCm38X85,701,937 - 85,776,819 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX85,701,937 - 85,776,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X82,947,276 - 83,022,158 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X81,954,656 - 82,029,402 (-)NCBIMGSCv36mm8
CeleraX76,897,628 - 76,973,181 (-)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-noradrenaline  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
alachlor  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
atazanavir sulfate  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
chenodeoxycholic acid  (ISO)
chloroacetic acid  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
ciglitazone  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
clorgyline  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (EXP,ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
Di-n-octyl phthalate  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (EXP)
difenoconazole  (EXP)
Diisodecyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethylselenide  (ISO)
diuron  (ISO)
dobutamine  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (EXP)
fenofibrate  (ISO)
finasteride  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
Ganoderic acid A  (EXP)
glafenine  (ISO)
glycerol  (EXP,ISO)
glycerol 1-phosphate  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydroquinone  (ISO)
hydroxyl  (ISO)
indometacin  (EXP,ISO)
inulin  (EXP)
irinotecan  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lovastatin  (EXP)
malathion  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (EXP)
Muraglitazar  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
parathion  (EXP)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
progesterone  (ISO)
propamocarb  (EXP)
propranolol  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
streptozocin  (EXP,ISO)
sulindac sulfide  (ISO)
Tesaglitazar  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IDA,ISO)
membrane  (IEA)
mitochondrial outer membrane  (IEA)
mitochondrion  (HDA,IBA,ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Clinical heterogeneity and novel mutations in the glycerol kinase gene in three families with isolated glycerol kinase deficiency. Sjarif DR, etal., J Med Genet. 1998 Aug;35(8):650-6.
11. Lipid and glucose utilization in hypercholesterolemic rats fed a diet containing heated chickpea (Cicer aretinum L.): a potential functional food. Zulet MA, etal., Int J Vitam Nutr Res. 1999 Nov;69(6):403-11. doi: 10.1024/0300-9831.69.6.403.
Additional References at PubMed
PMID:8884278   PMID:8889548   PMID:8889551   PMID:8921887   PMID:9090377   PMID:9302256   PMID:9393880   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11385633   PMID:12466305  
PMID:12477932   PMID:12520002   PMID:14610273   PMID:14651853   PMID:14681479   PMID:15489334   PMID:15681609   PMID:15782199   PMID:15845384   PMID:15957255   PMID:16009937   PMID:16105550  
PMID:16141072   PMID:16141073   PMID:16368706   PMID:17406644   PMID:18287559   PMID:18478268   PMID:18614015   PMID:18614564   PMID:18827223   PMID:19121967   PMID:19270708   PMID:19546021  
PMID:21386911   PMID:21536471   PMID:21677750   PMID:21873635   PMID:25505152   PMID:27713003   PMID:31813231   PMID:32273338   PMID:32325033   PMID:32581705   PMID:34321999   PMID:34551152  


Genomics

Comparative Map Data
Gk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X84,745,543 - 84,820,425 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX84,745,543 - 84,820,425 (-)EnsemblGRCm39 Ensembl
GRCm38X85,701,937 - 85,776,819 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX85,701,937 - 85,776,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X82,947,276 - 83,022,158 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X81,954,656 - 82,029,402 (-)NCBIMGSCv36mm8
CeleraX76,897,628 - 76,973,181 (-)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.32NCBI
GK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,653,423 - 30,731,462 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX30,653,359 - 30,731,462 (+)EnsemblGRCh38hg38GRCh38
GRCh37X30,671,540 - 30,749,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,581,461 - 30,658,646 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X30,431,196 - 30,508,381NCBI
CeleraX34,794,970 - 34,872,746 (+)NCBICelera
Cytogenetic MapXp21.2NCBI
HuRefX28,409,908 - 28,487,802 (+)NCBIHuRef
CHM1_1X30,702,368 - 30,780,409 (+)NCBICHM1_1
T2T-CHM13v2.0X30,247,310 - 30,325,392 (+)NCBIT2T-CHM13v2.0
Gk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,106,708 - 54,189,940 (-)NCBIGRCr8
mRatBN7.2X50,162,089 - 50,238,707 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,163,123 - 50,238,631 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX51,492,275 - 51,568,703 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X54,992,657 - 55,069,083 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X52,623,653 - 52,700,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X54,227,291 - 54,303,897 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,227,397 - 54,303,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X54,426,876 - 54,503,386 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X72,416,872 - 72,493,296 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X72,491,081 - 72,566,588 (-)NCBI
CeleraX50,789,241 - 50,865,448 (-)NCBICelera
Cytogenetic MapXq21NCBI
Gk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955531106,761 - 183,347 (-)NCBIChiLan1.0ChiLan1.0
GK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X32,451,539 - 32,528,605 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X32,454,918 - 32,531,984 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X23,250,290 - 23,327,373 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X30,806,950 - 30,876,075 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX30,806,950 - 30,877,131 (+)Ensemblpanpan1.1panPan2
GK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X25,748,060 - 25,834,462 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX30,724,675 - 30,810,642 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X25,779,221 - 25,865,989 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX25,788,453 - 25,865,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X25,824,618 - 25,911,312 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X25,818,511 - 25,904,987 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X25,914,905 - 26,001,706 (+)NCBIUU_Cfam_GSD_1.0
Gk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X18,614,780 - 18,776,739 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365536,707,148 - 6,787,245 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X26,470,422 - 26,558,892 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X28,788,865 - 28,872,354 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X29,043,390 - 29,119,516 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX29,043,571 - 29,118,646 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605631,026,654 - 31,105,211 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476225,270,270 - 25,357,167 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476225,268,398 - 25,357,165 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gk
1458 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4571
Count of miRNA genes:751
Interacting mature miRNAs:983
Transcripts:ENSMUST00000026039, ENSMUST00000113978, ENSMUST00000122950, ENSMUST00000124386, ENSMUST00000125081, ENSMUST00000142152, ENSMUST00000152221, ENSMUST00000156390
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
10412108Desp5_mdespair 5 (mouse)Not determinedX5472235188722351Mouse
13464140Hdlq108_mHDL QTL 108 (mouse)X5777196091771960Mouse
25314316Mlh1fc3_mMLH1 foci count 3 (mouse)X6134360689843606Mouse
25314318Sccor2_msynaptonemal complex length to mean MLH1 count ratio 2 (mouse)X7054360696543606Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
12879918Shm4_msperm head morphology 4 (mouse)X72072050102062720Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX75306671109306758Mouse
1302054Gct4_mgranulosa cell tumorigenesis 4 (mouse)Not determinedX76124336102062720Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse

Markers in Region
px-43c1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X85,741,413 - 85,741,637UniSTSGRCm38
MGSCv37X82,986,752 - 82,986,976UniSTSGRCm37
CeleraX76,937,175 - 76,937,399UniSTS
Cytogenetic MapXC-DUniSTS
Gyk  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXC-DUniSTS
cM MapX39.32UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001294138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001294140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001331046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_212444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006527829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006527831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006527833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK008186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB639153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ555961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB950214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF535556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF740682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK789590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB936831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB950510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC994240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HD007920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U48403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026039   ⟹   ENSMUSP00000026039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,745,543 - 84,820,425 (-)Ensembl
GRCm38.p6 EnsemblX85,701,937 - 85,776,819 (-)Ensembl
RefSeq Acc Id: ENSMUST00000113978   ⟹   ENSMUSP00000109611
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,745,543 - 84,820,259 (-)Ensembl
GRCm38.p6 EnsemblX85,701,937 - 85,776,653 (-)Ensembl
RefSeq Acc Id: ENSMUST00000122950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,756,001 - 84,758,064 (-)Ensembl
GRCm38.p6 EnsemblX85,712,395 - 85,714,458 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124386
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,756,298 - 84,781,216 (-)Ensembl
GRCm38.p6 EnsemblX85,712,692 - 85,737,610 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125081
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,802,126 - 84,805,588 (-)Ensembl
GRCm38.p6 EnsemblX85,758,520 - 85,761,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142152   ⟹   ENSMUSP00000120754
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,745,543 - 84,820,230 (-)Ensembl
GRCm38.p6 EnsemblX85,701,937 - 85,776,624 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,750,602 - 84,756,081 (-)Ensembl
GRCm38.p6 EnsemblX85,706,996 - 85,712,475 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156390   ⟹   ENSMUSP00000119564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX84,745,543 - 84,820,243 (-)Ensembl
GRCm38.p6 EnsemblX85,701,937 - 85,776,637 (-)Ensembl
RefSeq Acc Id: NM_001294138   ⟹   NP_001281067
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,745,543 - 84,820,425 (-)NCBI
GRCm38X85,701,937 - 85,776,819 (-)NCBI
CeleraX76,897,628 - 76,973,181 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001294140   ⟹   NP_001281069
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,745,543 - 84,820,425 (-)NCBI
GRCm38X85,701,937 - 85,776,819 (-)NCBI
CeleraX76,897,628 - 76,973,181 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001331046   ⟹   NP_001317975
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,745,543 - 84,820,425 (-)NCBI
GRCm38X85,701,937 - 85,776,819 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008194   ⟹   NP_032220
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,745,543 - 84,820,425 (-)NCBI
GRCm38X85,701,937 - 85,776,819 (-)ENTREZGENE
MGSCv37X82,947,276 - 83,022,158 (-)RGD
CeleraX76,897,628 - 76,973,181 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_212444   ⟹   NP_997609
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,745,543 - 84,820,425 (-)NCBI
GRCm38X85,701,937 - 85,776,819 (-)ENTREZGENE
MGSCv37X82,947,276 - 83,022,158 (-)RGD
CeleraX76,897,628 - 76,973,181 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006527829   ⟹   XP_006527892
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,746,201 - 84,820,420 (-)NCBI
GRCm38X85,702,595 - 85,776,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006527831   ⟹   XP_006527894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,746,201 - 84,820,420 (-)NCBI
GRCm38X85,702,595 - 85,776,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006527833   ⟹   XP_006527896
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X84,746,750 - 84,820,420 (-)NCBI
GRCm38X85,703,144 - 85,776,814 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_032220   ⟸   NM_008194
- Peptide Label: isoform 1
- UniProtKB: Q3TEN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_997609   ⟸   NM_212444
- Peptide Label: isoform 2
- UniProtKB: Q3TEN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006527894   ⟸   XM_006527831
- Peptide Label: isoform X2
- UniProtKB: Q3TET2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006527896   ⟸   XM_006527833
- Peptide Label: isoform X3
- UniProtKB: Q3TET2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006527892   ⟸   XM_006527829
- Peptide Label: isoform X1
- UniProtKB: Q3TET2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001281069   ⟸   NM_001294140
- Peptide Label: isoform 4
- UniProtKB: Q8C2M1 (UniProtKB/Swiss-Prot),   B1ASZ1 (UniProtKB/Swiss-Prot),   Q8C8X0 (UniProtKB/Swiss-Prot),   Q64516 (UniProtKB/Swiss-Prot),   Q3TEN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001281067   ⟸   NM_001294138
- Peptide Label: isoform 3
- UniProtKB: B1ASZ3 (UniProtKB/TrEMBL),   Q3TET2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001317975   ⟸   NM_001331046
- Peptide Label: isoform 5
- UniProtKB: Q3TEN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000026039   ⟸   ENSMUST00000026039
RefSeq Acc Id: ENSMUSP00000109611   ⟸   ENSMUST00000113978
RefSeq Acc Id: ENSMUSP00000120754   ⟸   ENSMUST00000142152
RefSeq Acc Id: ENSMUSP00000119564   ⟸   ENSMUST00000156390
Protein Domains
Carbohydrate kinase FGGY C-terminal   Carbohydrate kinase FGGY N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64516-F1-model_v2 AlphaFold Q64516 1-559 view protein structure

Promoters
RGD ID:6845820
Promoter ID:MM_KWN:61032
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver
Transcripts:OTTMUST00000043309
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X82,957,456 - 82,957,957 (-)MPROMDB
RGD ID:6845819
Promoter ID:MM_KWN:61033
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Kidney,   Lung
Transcripts:OTTMUST00000043308
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X82,959,969 - 82,960,469 (-)MPROMDB
RGD ID:6845642
Promoter ID:MM_KWN:61035
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:AK037750_E130114A11RIK,   OTTMUST00000043307
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X82,980,031 - 82,983,287 (-)MPROMDB
RGD ID:6845818
Promoter ID:MM_KWN:61037
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney
Transcripts:OTTMUST00000043306
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X83,006,936 - 83,007,917 (-)MPROMDB
RGD ID:6845817
Promoter ID:MM_KWN:61038
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000069684,   ENSMUST00000081161,   ENSMUST00000113978,   NM_008194,   NM_212444,   UC009TRY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X83,021,776 - 83,022,657 (-)MPROMDB
RGD ID:13680900
Promoter ID:EPDNEW_M24599
Type:initiation region
Name:Gk_1
Description:Mus musculus glycerol kinase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X85,776,618 - 85,776,678EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106594 AgrOrtholog
Ensembl Genes ENSMUSG00000025059 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026039 ENTREZGENE
  ENSMUST00000026039.15 UniProtKB/Swiss-Prot
  ENSMUST00000113978 ENTREZGENE
  ENSMUST00000113978.9 UniProtKB/Swiss-Prot
  ENSMUST00000142152 ENTREZGENE
  ENSMUST00000142152.2 UniProtKB/TrEMBL
  ENSMUST00000156390 ENTREZGENE
  ENSMUST00000156390.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carb_kinase_FGGY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carb_kinase_FGGY_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carb_kinase_FGGY_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carb_kinase_FGGY_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GK1-3_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycerol_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14933 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:106594 ENTREZGENE
NCBI Gene 14933 ENTREZGENE
PANTHER GLYCEROL KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGGY_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGGY_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gk PhenoGen
PIRSF GlpK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FGGY_KINASES_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGGY_KINASES_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1ASZ1 ENTREZGENE
  B1ASZ3 ENTREZGENE, UniProtKB/TrEMBL
  GLPK_MOUSE UniProtKB/Swiss-Prot
  Q3TEN9 ENTREZGENE, UniProtKB/TrEMBL
  Q3TET2 ENTREZGENE, UniProtKB/TrEMBL
  Q64516 ENTREZGENE
  Q8C2M1 ENTREZGENE
  Q8C8X0 ENTREZGENE
  Q9CVH5_MOUSE UniProtKB/TrEMBL
UniProt Secondary B1ASZ1 UniProtKB/Swiss-Prot
  Q8C2M1 UniProtKB/Swiss-Prot
  Q8C8X0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-04 Gk  glycerol kinase  Gyk    Symbol and/or name change 5135510 APPROVED