Akr1d1 Mouse 1,1-dichloroethene decreases expression EXP 6480464 vinylidene chloride results in decreased expression of AKR1D1 mRNA CTD PMID:26682919 Akr1d1 Mouse 17beta-estradiol decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Estradiol results in decreased expression of AKR1D1 mRNA CTD PMID:20106945 and PMID:21632981 Akr1d1 Mouse 17beta-estradiol affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 Estradiol affects the expression of AKR1D1 mRNA CTD PMID:32145629 Akr1d1 Mouse 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO AKR1D1 (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of AKR1D1 mRNA CTD PMID:29581250 Akr1d1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:27291303 and PMID:31826744 Akr1d1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:30294300 Akr1d1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO AKR1D1 (Homo sapiens) 6480464 2 more ... CTD PMID:31173147 Akr1d1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:27291303 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1D1 mRNA CTD PMID:19770486 and PMID:28213091 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to AKR1D1 gene] CTD PMID:28213091 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1D1 mRNA CTD PMID:20959002 and PMID:21215274 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1D1 mRNA CTD PMID:21632981 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1D1 mRNA CTD PMID:22298810 Akr1d1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO AKR1D1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1D1 mRNA CTD PMID:20106945 and PMID:22298810 Akr1d1 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression EXP 6480464 2 more ... CTD PMID:38648751 Akr1d1 Mouse 3,3',4,4',5-pentachlorobiphenyl increases expression ISO AKR1D1 (Homo sapiens) 6480464 3 more ... CTD PMID:19692669 Akr1d1 Mouse 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:20959002 Akr1d1 Mouse 3-chloropropane-1,2-diol affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin analog affects the expression of AKR1D1 protein CTD PMID:26597043 Akr1d1 Mouse 3alpha-hydroxy-5beta-androstan-17-one increases chemical synthesis EXP 6480464 AKR1D1 protein alternative form results in increased chemical synthesis of Etiocholanolone and AKR1D1 protein results in increased chemical synthesis of Etiocholanolone CTD PMID:30928400 Akr1d1 Mouse 3alpha-hydroxy-5beta-androstan-17-one multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased metabolism of androstane-3 more ... CTD PMID:30928400 Akr1d1 Mouse 3H-1,2-dithiole-3-thione increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in increased expression of AKR1D1 mRNA CTD PMID:19162173 Akr1d1 Mouse 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AKR1D1 mRNA CTD PMID:18648102 Akr1d1 Mouse 4,4'-sulfonyldiphenol increases methylation ISO AKR1D1 (Homo sapiens) 6480464 bisphenol S results in increased methylation of AKR1D1 gene CTD PMID:31601247 Akr1d1 Mouse 4,4'-sulfonyldiphenol multiple interactions ISO Akr1d1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of AKR1D1 mRNA CTD PMID:36041667 Akr1d1 Mouse 5-Dihydrocortisol multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased reduction of Hydrocortisone] which results in increased chemical synthesis of 5-dihydrocortisol CTD PMID:30928400 Akr1d1 Mouse 5-Dihydrocortisol increases chemical synthesis EXP 6480464 AKR1D1 protein alternative form results in increased chemical synthesis of 5-dihydrocortisol CTD PMID:30928400 Akr1d1 Mouse 5alpha-pregnane-3,20-dione increases chemical synthesis ISO AKR1D1 (Homo sapiens) 6480464 AKR1D1 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:18624455 Akr1d1 Mouse 5alpha-pregnane-3,20-dione increases chemical synthesis EXP 6480464 AKR1D1 protein alternative form results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:30928400 Akr1d1 Mouse 5alpha-pregnane-3,20-dione multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased reduction of Progesterone] which results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:30928400 Akr1d1 Mouse 7alpha-hydroxycholest-4-en-3-one multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of 7 alpha-hydroxy-4-cholesten-3-one and AKR1D1 gene mutant form inhibits the reaction [AKR1D1 protein results in increased metabolism of 7 alpha-hydroxy-4-cholesten-3-one] CTD PMID:21185810 and PMID:25500266 Akr1d1 Mouse acetamide decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 acetamide results in decreased expression of AKR1D1 mRNA CTD PMID:31881176 Akr1d1 Mouse actinomycin D multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of AKR1D1 mRNA CTD PMID:38460933 Akr1d1 Mouse aflatoxin B1 affects expression ISO AKR1D1 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of AKR1D1 protein CTD PMID:20106945 Akr1d1 Mouse aflatoxin B1 decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of AKR1D1 intron CTD PMID:30157460 Akr1d1 Mouse aflatoxin B1 decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of AKR1D1 mRNA CTD PMID:21632981 more ... Akr1d1 Mouse aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of AKR1D1 mRNA CTD PMID:19770486 Akr1d1 Mouse Aflatoxin B2 alpha decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of AKR1D1 intron CTD PMID:30157460 Akr1d1 Mouse aldosterone multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of Aldosterone CTD PMID:25500266 Akr1d1 Mouse ammonium chloride affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of AKR1D1 mRNA CTD PMID:16483693 Akr1d1 Mouse androst-4-ene-3,17-dione increases reduction ISO AKR1D1 (Homo sapiens) 6480464 AKR1D1 protein results in increased reduction of Androstenedione CTD PMID:30928400 Akr1d1 Mouse androst-4-ene-3,17-dione multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased reduction of Androstenedione] which results in increased chemical synthesis of androstane-3 more ... CTD PMID:30928400 Akr1d1 Mouse androst-4-ene-3,17-dione increases reduction EXP 6480464 AKR1D1 protein alternative form results in increased reduction of Androstenedione and AKR1D1 protein results in increased reduction of Androstenedione CTD PMID:30928400 Akr1d1 Mouse androstane-3,17-dione multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased metabolism of androstane-3 more ... CTD PMID:30928400 Akr1d1 Mouse androstane-3,17-dione increases metabolic processing EXP 6480464 AKR1D1 protein alternative form results in increased metabolism of androstane-3 more ... CTD PMID:30928400 Akr1d1 Mouse androstane-3,17-dione increases chemical synthesis EXP 6480464 AKR1D1 protein alternative form results in increased chemical synthesis of androstane-3 more ... CTD PMID:30928400 Akr1d1 Mouse atazanavir sulfate multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse azathioprine decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Azathioprine results in decreased expression of AKR1D1 mRNA CTD PMID:22623647 Akr1d1 Mouse benzo[a]pyrene affects expression ISO AKR1D1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the expression of AKR1D1 mRNA CTD PMID:20106945 Akr1d1 Mouse benzo[a]pyrene affects methylation ISO AKR1D1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of AKR1D1 intron and Benzo(a)pyrene affects the methylation of AKR1D1 promoter CTD PMID:27901495 and PMID:30157460 Akr1d1 Mouse benzo[a]pyrene decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of AKR1D1 mRNA CTD PMID:21632981 more ... Akr1d1 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of AKR1D1 mRNA CTD PMID:19770486 Akr1d1 Mouse benzo[e]pyrene decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of AKR1D1 intron CTD PMID:30157460 Akr1d1 Mouse beta-naphthoflavone decreases expression ISO AKR1D1 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of AKR1D1 mRNA CTD PMID:19737606 Akr1d1 Mouse bisphenol A decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of AKR1D1 mRNA CTD PMID:25181051 Akr1d1 Mouse bisphenol A multiple interactions ISO Akr1d1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of AKR1D1 mRNA CTD PMID:36041667 Akr1d1 Mouse bisphenol A decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of AKR1D1 gene CTD PMID:31601247 Akr1d1 Mouse bisphenol A affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of AKR1D1 mRNA CTD PMID:32145629 Akr1d1 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKR1D1 mRNA CTD PMID:30245210 Akr1d1 Mouse bisphenol A affects expression ISO AKR1D1 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR1D1 mRNA CTD PMID:30903817 Akr1d1 Mouse bisphenol F multiple interactions ISO Akr1d1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of AKR1D1 mRNA CTD PMID:36041667 Akr1d1 Mouse butan-1-ol multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of AKR1D1 mRNA CTD PMID:29432896 Akr1d1 Mouse cadmium atom increases expression ISO AKR1D1 (Homo sapiens) 6480464 Cadmium results in increased expression of AKR1D1 mRNA CTD PMID:21120746 Akr1d1 Mouse carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25620056 Akr1d1 Mouse cefaloridine increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Cephaloridine results in increased expression of AKR1D1 mRNA CTD PMID:18172885 Akr1d1 Mouse chenodeoxycholic acid multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA more ... CTD PMID:33819548 Akr1d1 Mouse chloropicrin increases expression ISO AKR1D1 (Homo sapiens) 6480464 chloropicrin results in increased expression of AKR1D1 mRNA CTD PMID:26352163 Akr1d1 Mouse chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of AKR1D1 mRNA CTD PMID:37019170 Akr1d1 Mouse cholest-4-en-3-one multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of cholest-4-en-3-one CTD PMID:25500266 Akr1d1 Mouse choline multiple interactions EXP 6480464 [Dietary Fats co-treated with Choline deficiency] results in decreased expression of AKR1D1 mRNA and PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in decreased expression of AKR1D1 mRNA] CTD PMID:29246445 Akr1d1 Mouse cisplatin increases expression ISO AKR1D1 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR1D1 mRNA CTD PMID:27392435 Akr1d1 Mouse cobalt dichloride decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 cobaltous chloride results in decreased expression of AKR1D1 mRNA CTD PMID:24386269 Akr1d1 Mouse cocaine affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 Akr1d1 Mouse copper(II) sulfate decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of AKR1D1 mRNA CTD PMID:19549813 Akr1d1 Mouse corticosterone multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of Corticosterone CTD PMID:25500266 Akr1d1 Mouse cortisol increases reduction ISO AKR1D1 (Homo sapiens) 6480464 AKR1D1 protein results in increased reduction of Hydrocortisone CTD PMID:30928400 Akr1d1 Mouse cortisol multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased reduction of Hydrocortisone] which results in increased chemical synthesis of 5-dihydrocortisol CTD PMID:30928400 Akr1d1 Mouse cortisol increases reduction EXP 6480464 AKR1D1 protein alternative form results in increased reduction of Hydrocortisone and AKR1D1 protein results in increased reduction of Hydrocortisone CTD PMID:30928400 Akr1d1 Mouse cortisone multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of Cortisone CTD PMID:25500266 Akr1d1 Mouse coumarin affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 coumarin affects the expression of AKR1D1 mRNA CTD PMID:16963487 Akr1d1 Mouse cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of AKR1D1 mRNA CTD PMID:23830897 Akr1d1 Mouse cyclosporin A multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse cyclosporin A decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AKR1D1 mRNA CTD PMID:20106945 more ... Akr1d1 Mouse decabromodiphenyl ether increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of AKR1D1 mRNA CTD PMID:23914054 Akr1d1 Mouse deoxycholic acid multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA more ... CTD PMID:33819548 Akr1d1 Mouse dicrotophos decreases expression ISO AKR1D1 (Homo sapiens) 6480464 dicrotophos results in decreased expression of AKR1D1 mRNA CTD PMID:28302478 Akr1d1 Mouse endosulfan decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of AKR1D1 mRNA CTD PMID:29391264 Akr1d1 Mouse ethanol increases expression EXP 6480464 Ethanol results in increased expression of AKR1D1 mRNA CTD PMID:19167417 Akr1d1 Mouse ethyl methanesulfonate increases expression ISO AKR1D1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of AKR1D1 mRNA CTD PMID:23649840 Akr1d1 Mouse flutamide increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of AKR1D1 mRNA CTD PMID:24136188 Akr1d1 Mouse flutamide decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Flutamide results in decreased expression of AKR1D1 mRNA CTD PMID:24793618 Akr1d1 Mouse formaldehyde increases expression ISO AKR1D1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of AKR1D1 mRNA CTD PMID:23649840 Akr1d1 Mouse gentamycin increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of AKR1D1 mRNA CTD PMID:18172885 Akr1d1 Mouse glutathione increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of AKR1D1 mRNA CTD PMID:15345336 Akr1d1 Mouse glycochenodeoxycholic acid multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA more ... CTD PMID:33819548 Akr1d1 Mouse glycocholic acid multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA more ... CTD PMID:33819548 Akr1d1 Mouse glycodeoxycholic acid multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA more ... CTD PMID:33819548 Akr1d1 Mouse inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR1D1 mRNA CTD PMID:36331819 Akr1d1 Mouse iodide salt increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Iodides deficiency results in increased expression of AKR1D1 protein CTD PMID:26795019 Akr1d1 Mouse ivermectin decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR1D1 protein CTD PMID:32959892 Akr1d1 Mouse Lasiocarpine decreases expression ISO AKR1D1 (Homo sapiens) 6480464 lasiocarpine results in decreased expression of AKR1D1 mRNA CTD PMID:32234424 Akr1d1 Mouse limonene decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 limonene results in decreased expression of AKR1D1 mRNA CTD PMID:12815608 Akr1d1 Mouse lipopolysaccharide multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of AKR1D1 mRNA CTD PMID:35811015 Akr1d1 Mouse metacetamol decreases expression EXP 6480464 3-hydroxyacetanilide results in decreased expression of AKR1D1 mRNA CTD PMID:18544908 Akr1d1 Mouse methapyrilene decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of AKR1D1 intron CTD PMID:30157460 Akr1d1 Mouse methapyrilene increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of AKR1D1 protein CTD PMID:30467583 Akr1d1 Mouse methapyrilene decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Methapyrilene results in decreased expression of AKR1D1 mRNA CTD PMID:30467583 Akr1d1 Mouse methyl methanesulfonate increases expression ISO AKR1D1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of AKR1D1 mRNA CTD PMID:23649840 Akr1d1 Mouse methylmercury chloride decreases expression ISO AKR1D1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of AKR1D1 mRNA CTD PMID:23179753 Akr1d1 Mouse Muraglitazar increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 muraglitazar results in increased expression of AKR1D1 mRNA CTD PMID:21515302 Akr1d1 Mouse N-nitrosodiethylamine decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Diethylnitrosamine results in decreased expression of AKR1D1 mRNA CTD PMID:20360939 Akr1d1 Mouse NADP zwitterion multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of 7 alpha-hydroxy-4-cholesten-3-one more ... CTD PMID:25500266 Akr1d1 Mouse NADP(+) multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of 7 alpha-hydroxy-4-cholesten-3-one more ... CTD PMID:25500266 Akr1d1 Mouse nefazodone increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 nefazodone results in increased expression of AKR1D1 mRNA CTD PMID:24136188 Akr1d1 Mouse nefazodone multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse nickel dichloride affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 nickel chloride affects the expression of AKR1D1 mRNA CTD PMID:22110744 Akr1d1 Mouse nitrofen increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 nitrofen results in increased expression of AKR1D1 mRNA CTD PMID:33484710 Akr1d1 Mouse Nutlin-3 multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of AKR1D1 mRNA CTD PMID:38460933 Akr1d1 Mouse O-methyleugenol decreases expression ISO AKR1D1 (Homo sapiens) 6480464 methyleugenol results in decreased expression of AKR1D1 mRNA CTD PMID:32234424 Akr1d1 Mouse obeticholic acid decreases expression ISO AKR1D1 (Homo sapiens) 6480464 obeticholic acid results in decreased expression of AKR1D1 mRNA CTD PMID:27939613 Akr1d1 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of AKR1D1 mRNA CTD PMID:17562736 Akr1d1 Mouse paracetamol multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse paracetamol decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of AKR1D1 mRNA CTD PMID:29067470 Akr1d1 Mouse paracetamol multiple interactions EXP 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of AKR1D1 mRNA] CTD PMID:29246445 Akr1d1 Mouse paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of AKR1D1 mRNA CTD PMID:18544908 and PMID:29246445 Akr1d1 Mouse perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of AKR1D1 mRNA CTD PMID:19429403 Akr1d1 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR1D1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of AKR1D1 mRNA CTD PMID:36331819 Akr1d1 Mouse perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of AKR1D1 mRNA CTD PMID:17681415 and PMID:19429403 Akr1d1 Mouse perfluorooctanoic acid decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of AKR1D1 mRNA CTD PMID:19162173 Akr1d1 Mouse phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of AKR1D1 mRNA CTD PMID:19270015 Akr1d1 Mouse phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of AKR1D1 mRNA CTD PMID:23091169 Akr1d1 Mouse phenobarbital increases expression ISO AKR1D1 (Homo sapiens) 6480464 Phenobarbital results in increased expression of AKR1D1 mRNA CTD PMID:19084549 Akr1d1 Mouse pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of AKR1D1 mRNA CTD PMID:20813756 Akr1d1 Mouse pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AKR1D1 mRNA CTD PMID:19710929 Akr1d1 Mouse pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of AKR1D1 mRNA CTD PMID:28903501 Akr1d1 Mouse progesterone increases reduction ISO AKR1D1 (Homo sapiens) 6480464 AKR1D1 protein results in increased reduction of Progesterone CTD PMID:18624455 Akr1d1 Mouse progesterone multiple interactions EXP 6480464 [AKR1D1 protein alternative form results in increased reduction of Progesterone] which results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:30928400 Akr1d1 Mouse progesterone increases reduction EXP 6480464 AKR1D1 protein alternative form results in increased reduction of Progesterone and AKR1D1 protein results in increased reduction of Progesterone CTD PMID:30928400 Akr1d1 Mouse propiconazole increases expression EXP 6480464 propiconazole results in increased expression of AKR1D1 mRNA CTD PMID:21278054 Akr1d1 Mouse Propiverine affects binding ISO Akr1d1 (Rattus norvegicus) 6480464 propiverine binds to AKR1D1 protein CTD PMID:29273565 Akr1d1 Mouse quercetin decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Quercetin results in decreased expression of AKR1D1 mRNA CTD PMID:21632981 Akr1d1 Mouse rotenone decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Rotenone results in decreased expression of AKR1D1 mRNA CTD PMID:29955902 Akr1d1 Mouse S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of AKR1D1 mRNA CTD PMID:35811015 Akr1d1 Mouse simvastatin decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Simvastatin results in decreased expression of AKR1D1 mRNA CTD PMID:25055962 Akr1d1 Mouse sodium arsenite decreases expression ISO AKR1D1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of AKR1D1 mRNA CTD PMID:29301061 Akr1d1 Mouse sodium arsenite increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of AKR1D1 protein CTD PMID:29459688 Akr1d1 Mouse sodium dichromate affects expression ISO Akr1d1 (Rattus norvegicus) 6480464 sodium bichromate affects the expression of AKR1D1 mRNA CTD PMID:22110744 Akr1d1 Mouse Sunset Yellow FCF multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse tartrazine multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 Akr1d1 Mouse tauroursodeoxycholic acid decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 ursodoxicoltaurine results in decreased expression of AKR1D1 mRNA CTD PMID:15885361 Akr1d1 Mouse testosterone decreases expression EXP 6480464 Testosterone results in decreased expression of AKR1D1 mRNA CTD PMID:21669218 Akr1d1 Mouse testosterone multiple interactions ISO AKR1D1 (Homo sapiens) 6480464 [AKR1D1 protein co-treated with NADP] results in increased reduction of Testosterone and AKR1D1 gene mutant form inhibits the reaction [AKR1D1 protein results in increased metabolism of Testosterone] CTD PMID:21185810 and PMID:25500266 Akr1d1 Mouse tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of AKR1D1 mRNA CTD PMID:27339419 and PMID:31919559 Akr1d1 Mouse tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of AKR1D1 mRNA CTD PMID:16917069 Akr1d1 Mouse thioacetamide increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of AKR1D1 mRNA CTD PMID:26222700 Akr1d1 Mouse thioacetamide decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of AKR1D1 mRNA CTD PMID:34492290 Akr1d1 Mouse tolcapone affects binding ISO Akr1d1 (Rattus norvegicus) 6480464 tolcapone binds to AKR1D1 protein CTD PMID:19783845 Akr1d1 Mouse troglitazone increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 troglitazone results in increased expression of AKR1D1 mRNA and troglitazone results in increased expression of AKR1D1 protein CTD PMID:21315101 and PMID:21515302 Akr1d1 Mouse urethane decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Urethane results in decreased expression of AKR1D1 mRNA CTD PMID:28818685 Akr1d1 Mouse valproic acid increases expression ISO AKR1D1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of AKR1D1 mRNA CTD PMID:29154799 Akr1d1 Mouse valproic acid increases expression ISO Akr1d1 (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of AKR1D1 mRNA CTD PMID:35594946 Akr1d1 Mouse valproic acid decreases expression ISO AKR1D1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of AKR1D1 mRNA CTD PMID:23179753 and PMID:27188386 Akr1d1 Mouse valproic acid affects expression ISO AKR1D1 (Homo sapiens) 6480464 Valproic Acid affects the expression of AKR1D1 mRNA CTD PMID:25979313 Akr1d1 Mouse valproic acid decreases methylation ISO AKR1D1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of AKR1D1 gene CTD PMID:29154799 Akr1d1 Mouse vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of AKR1D1 mRNA CTD PMID:18930951 Akr1d1 Mouse vinclozolin decreases expression ISO Akr1d1 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of AKR1D1 mRNA CTD PMID:22615374 Akr1d1 Mouse XL147 multiple interactions EXP 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of AKR1D1 mRNA CTD PMID:27935865