Gene: Akr1d1 (aldo-keto reductase family 1, member D1) Rattus norvegicus
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Symbol: Akr1d1
Name: aldo-keto reductase family 1, member D1
Description: ENCODES a protein that exhibits 3-oxo-5-beta-steroid 4-dehydrogenase activity; INVOLVED IN androgen metabolic process (ortholog); bile acid biosynthetic process (ortholog); C21-steroid hormone metabolic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH congenital bile acid synthesis defect (ortholog); congenital bile acid synthesis defect 2 (ortholog); hemochromatosis (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-oxo-5-beta-steroid 4-dehydrogenase; aldo-keto reductase family 1 member D1; aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase); delta(4)-3-ketosteroid 5-beta-reductase; delta(4)-3-oxosteroid 5-beta-reductase
Orthologs:
Homo sapiens (human) : AKR1D1 (aldo-keto reductase family 1 member D1)  HGNC  Alliance
Mus musculus (house mouse) : Akr1d1 (aldo-keto reductase family 1, member D1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akr1d1 (aldo-keto reductase family 1 member D1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKR1D1 (aldo-keto reductase family 1 member D1)
Canis lupus familiaris (dog) : LOC491379 (3-oxo-5-beta-steroid 4-dehydrogenase-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr1d1 (aldo-keto reductase family 1 member D1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0465,110,706 - 65,143,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0464,933,143 - 64,965,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4464,972,908 - 65,005,896 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1465,249,037 - 65,282,026 (+)NCBI
Celera461,186,796 - 61,219,854 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Akr1d1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620752
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-05-29
Status: ACTIVE