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Gene: Pth (parathyroid hormone) Mus musculus
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Symbol: Pth
Name: parathyroid hormone
RGD ID: 11186
Description: Exhibits hormone activity. Involved in several processes, including inorganic ion homeostasis; negative regulation of apoptotic process in bone marrow cell; and positive regulation of cell population proliferation. Localizes to extracellular space. Is expressed in 2nd branchial arch; 3rd branchial pouch; 3rd branchial pouch dorsal endoderm; foregut gland; and parathyroid gland. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Orthologous to human PTH (parathyroid hormone); PARTICIPATES IN parathyroid hormone signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC117651; Pthp
Orthologs:
Homo sapiens (human) : PTH (parathyroid hormone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pth (parathyroid hormone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pth (parathyroid hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : PTH (parathyroid hormone)
Canis lupus familiaris (dog) : PTH (parathyroid hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pth (parathyroid hormone)
Sus scrofa (pig) : PTH (parathyroid hormone)
Chlorocebus sabaeus (African green monkey) : PTH (parathyroid hormone)
Heterocephalus glaber (naked mole-rat) : Pth (parathyroid hormone)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397112,984,783 - 112,987,879 (-)NCBI
GRCm387113,385,576 - 113,388,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7113,385,580 - 113,388,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv377120,529,090 - 120,532,087 (-)NCBIGRCm37mm9NCBIm37
MGSCv367113,176,759 - 113,179,753 (-)NCBImm8
Celera7113,358,705 - 113,361,703 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pth
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11186
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.