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Gene: Pomc (pro-opiomelanocortin-alpha) Mus musculus
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Symbol: Pomc
Name: pro-opiomelanocortin-alpha
Description: Exhibits hormone activity. Involved in several processes, including glucose homeostasis; regulation of corticosterone secretion; and regulation of glycogen metabolic process. Localizes to the extracellular space and secretory granule. Used to study obesity. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Is expressed in several structures, including nervous system; skin; and trophoblast giant cell. Orthologous to human POMC (proopiomelanocortin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACTH; adrenal corticotropic hormone; adrenocorticotropic hormone; alpha-melanocyte stimulating hormone; alpha-MSH; alphaMSH; BE; beta-endorphin; Beta-LPH; beta-melanocyte stimulating hormone; beta-MSH; Clip; corticotropin-like intermediary peptide; corticotropin-lipotropin; Gamma-LPH; gamma-melanocyte stimulating hormone; gamma-MSH; melanotropin gamma; met-enkephalin; Npp; Pomc-1; Pomc1; pro-opiomelanocortin
Orthologs:
Homo sapiens (human) : POMC (proopiomelanocortin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pomc (proopiomelanocortin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pomc (proopiomelanocortin)
Pan paniscus (bonobo/pygmy chimpanzee) : POMC (proopiomelanocortin)
Canis lupus familiaris (dog) : POMC (proopiomelanocortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pomc (proopiomelanocortin)
Sus scrofa (pig) : POMC (proopiomelanocortin)
Chlorocebus sabaeus (African green monkey) : POMC (proopiomelanocortin)
Heterocephalus glaber (naked mole-rat) : Pomc (proopiomelanocortin)
more info ...
Related Pseudogenes: Pomc-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl123,954,951 - 3,960,642 (+)Ensembl
GRCm38123,954,945 - 3,960,643 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37123,954,951 - 3,960,618 (+)NCBIGRCm37mm9NCBIm37
MGSCv36123,954,967 - 3,960,634 (+)NCBImm8
Celera123,882,688 - 3,888,382 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pomc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1331975
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.