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Gene: Ank (progressive ankylosis) Mus musculus
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Symbol: Ank
Name: progressive ankylosis
Description: Exhibits inorganic diphosphate transmembrane transporter activity. Involved in regulation of bone mineralization. Localizes to the integral component of plasma membrane. Used to study craniometaphyseal dysplasia. Human ortholog(s) of this gene implicated in chondrocalcinosis. Is expressed in several structures, including bone; connective tissue; olfactory epithelium; telencephalon; and vibrissa follicle. Orthologous to human ANKH (ANKH inorganic pyrophosphate transport regulator); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ankh; D15Ertd221e; fn54 protein; mKIAA1581; progressive ankylosis protein
Orthologs:
Homo sapiens (human) : ANKH (ANKH inorganic pyrophosphate transport regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ankh (ANKH inorganic pyrophosphate transport regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ankh (ANKH inorganic pyrophosphate transport regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : ANKH (ANKH inorganic pyrophosphate transport regulator)
Canis lupus familiaris (dog) : ANKH (ANKH inorganic pyrophosphate transport regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ankh (ANKH inorganic pyrophosphate transport regulator)
Sus scrofa (pig) : ANKH (ANKH inorganic pyrophosphate transport regulator)
Chlorocebus sabaeus (green monkey) : ANKH (ANKH inorganic pyrophosphate transport regulator)
Heterocephalus glaber (naked mole-rat) : Ankh (ANKH inorganic pyrophosphate transport regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1527,466,677 - 27,594,909 (+)Ensembl
GRCm381527,466,677 - 27,594,909 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371527,396,432 - 27,524,664 (+)NCBIGRCm37mm9NCBIm37
MGSCv361527,411,402 - 27,539,630 (+)NCBImm8
Celera1528,214,608 - 28,342,822 (+)NCBICelera
Cytogenetic Map15 B1NCBI
cM Map1510.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ank
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734406
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.