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Gene: Anpep (alanyl (membrane) aminopeptidase) Mus musculus
Symbol: Anpep
Name: alanyl (membrane) aminopeptidase
Description: Predicted to have metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of renal sodium excretion; peptide catabolic process; and proteolysis. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and sensory organ. Orthologous to human ANPEP (alanyl aminopeptidase, membrane); PARTICIPATES IN angiotensin IV signaling pathway; glutathione metabolic pathway; glutathione synthase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alanyl aminopeptidase; aminopeptidase M; aminopeptidase N; aminopeptidase N/CD13; AP-M; AP-N; Apn; Cd13; Lap-1; Lap1; leucine arylaminopeptidase 1, intestinal; mAPN; membrane protein p161; microsomal aminopeptidase; P150
Homo sapiens (human) : ANPEP (alanyl aminopeptidase, membrane)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Anpep (alanyl aminopeptidase, membrane)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anpep (alanyl aminopeptidase, membrane)
Pan paniscus (bonobo/pygmy chimpanzee) : ANPEP (alanyl aminopeptidase, membrane)
Canis lupus familiaris (dog) : ANPEP (alanyl aminopeptidase, membrane)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anpep (alanyl aminopeptidase, membrane)
Sus scrofa (pig) : ANPEP (alanyl aminopeptidase, membrane)
Chlorocebus sabaeus (African green monkey) : ANPEP (alanyl aminopeptidase, membrane)
Heterocephalus glaber (naked mole-rat) : Anpep (alanyl aminopeptidase, membrane)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl779,821,803 - 79,861,059 (-)EnsemblGRCm38mm10GRCm38
GRCm38779,821,803 - 79,848,210 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37786,966,689 - 86,987,238 (-)NCBIGRCm37mm9NCBIm37
MGSCv36779,695,316 - 79,715,797 (-)NCBImm8
Celera777,221,100 - 77,243,027 (-)NCBICelera
Cytogenetic Map7D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Anpep
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10858
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.