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Gene: Fgf1 (fibroblast growth factor 1) Mus musculus
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Symbol: Fgf1
Name: fibroblast growth factor 1
RGD ID: 10577
Description: Predicted to have several functions, including Hsp70 protein binding activity; S100 protein binding activity; and signaling receptor binding activity. Involved in several processes, including organ induction; positive regulation of epithelial cell proliferation; and positive regulation of nitrogen compound metabolic process. Localizes to extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Orthologous to human FGF1 (fibroblast growth factor 1); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acidic fibroblast growth factor; aFGF; Dffrx; Fam; Fgf; Fgf-1; Fgfa; fibroblast growth factor 1 (acidic); HBGF-1; heparin-binding growth factor 1
Orthologs:
Homo sapiens (human) : FGF1 (fibroblast growth factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgf1 (fibroblast growth factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf1 (fibroblast growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF1 (fibroblast growth factor 1)
Canis lupus familiaris (dog) : FGF1 (fibroblast growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf1 (fibroblast growth factor 1)
Sus scrofa (pig) : FGF1 (fibroblast growth factor 1)
Chlorocebus sabaeus (African green monkey) : FGF1 (fibroblast growth factor 1)
Heterocephalus glaber (naked mole-rat) : Fgf1 (fibroblast growth factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,971,725 - 39,062,532 (-)NCBI
GRCm381838,838,672 - 38,929,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1838,838,673 - 38,929,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,998,327 - 39,078,353 (-)NCBIGRCm37mm9NCBIm37
MGSCv361838,965,154 - 39,044,673 (-)NCBImm8
Celera1840,186,840 - 40,265,902 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1820.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fgf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10577
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.