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Gene: Fgf1 (fibroblast growth factor 1) Mus musculus
Symbol: Fgf1
Name: fibroblast growth factor 1
RGD ID: 10577
Description: Predicted to have several functions, including Hsp70 protein binding activity; S100 protein binding activity; and signaling receptor binding activity. Involved in several processes, including organ induction; positive regulation of epithelial cell proliferation; and positive regulation of nitrogen compound metabolic process. Localizes to extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Orthologous to human FGF1 (fibroblast growth factor 1); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acidic fibroblast growth factor; aFGF; Dffrx; Fam; Fgf; Fgf-1; Fgfa; fibroblast growth factor 1 (acidic); HBGF-1; heparin-binding growth factor 1
Homo sapiens (human) : FGF1 (fibroblast growth factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgf1 (fibroblast growth factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf1 (fibroblast growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF1 (fibroblast growth factor 1)
Canis lupus familiaris (dog) : FGF1 (fibroblast growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf1 (fibroblast growth factor 1)
Sus scrofa (pig) : FGF1 (fibroblast growth factor 1)
Chlorocebus sabaeus (African green monkey) : FGF1 (fibroblast growth factor 1)
Heterocephalus glaber (naked mole-rat) : Fgf1 (fibroblast growth factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391838,971,725 - 39,062,532 (-)NCBI
GRCm381838,838,672 - 38,929,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1838,838,673 - 38,929,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,998,327 - 39,078,353 (-)NCBIGRCm37mm9NCBIm37
MGSCv361838,965,154 - 39,044,673 (-)NCBImm8
Celera1840,186,840 - 40,265,902 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1820.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fgf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10577
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.