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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736867
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc3
Name: ATP-binding cassette, sub-family C member 3
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3increases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNAPMID:15833929 PMID:23994337
Abcc3multiple interactionsEXP 6480464CTD[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNAPMID:15833929
Abcc3increases expressionISOAbcc3 (Rattus norvegicus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNAPMID:20959002
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