Il11 (interleukin 11) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Il11 (interleukin 11) Mus musculus
Analyze
Symbol: Il11
Name: interleukin 11
RGD ID: 732129
MGI Page MGI
Description: Enables cytokine activity and interleukin-11 receptor binding activity. Acts upstream of or within positive regulation of cell population proliferation. Located in cytoplasm. Is expressed in liver. Orthologous to human IL11 (interleukin 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IL-; IL-11; interleukin-11
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,775,372 - 4,785,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,775,372 - 4,785,858 (-)EnsemblGRCm39 Ensembl
GRCm3874,772,373 - 4,782,907 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,772,373 - 4,782,859 (-)EnsemblGRCm38mm10GRCm38
MGSCv3774,724,657 - 4,729,743 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,376,142 - 4,381,118 (-)NCBIMGSCv36mm8
Celera74,502,811 - 4,507,897 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
aspartame  (ISO)
astaxanthin  (EXP)
azathioprine  (ISO)
Azoxymethane  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Brevianamide A  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
DDE  (ISO)
deoxynivalenol  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diallyl disulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ferulic acid  (EXP)
flurbiprofen  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (ISO)
graphene oxide  (EXP)
GW 4064  (EXP)
hydrogen peroxide  (ISO)
imiquimod  (EXP)
indometacin  (EXP,ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
malathion  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP)
menadione  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
mycophenolic acid  (EXP)
naphthalene  (EXP)
nickel sulfate  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paricalcitol  (ISO)
pemetrexed  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
Primycin  (ISO)
progesterone  (ISO)
propanal  (ISO)
prostaglandin E2  (EXP)
PX-866  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
riddelliine  (ISO)
Ro 31-8220  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sterigmatocystin  (EXP)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
TMC-120A  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
extracellular space  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning of rat interleukin 11 and interleukin 11 receptor alpha chain and analysis of their expression in rat uterus in the peri-implantation period. Li R, etal., Reproduction 2001 Oct;122(4):593-600.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1375116   PMID:1381512   PMID:2145578   PMID:7499280   PMID:7508917   PMID:7536685   PMID:7540890   PMID:7690439   PMID:7957045   PMID:8401258   PMID:8683938   PMID:8707872  
PMID:8812484   PMID:8913282   PMID:9090788   PMID:9124575   PMID:9166826   PMID:9488033   PMID:9500603   PMID:9528935   PMID:9548510   PMID:9558377   PMID:9679067   PMID:10349636  
PMID:11042159   PMID:11076861   PMID:11154224   PMID:11217851   PMID:11737071   PMID:12110441   PMID:12384500   PMID:12477932   PMID:12527946   PMID:12730876   PMID:12791389   PMID:12842083  
PMID:12929935   PMID:14610273   PMID:15499555   PMID:16141072   PMID:16141073   PMID:16143138   PMID:16720575   PMID:16959875   PMID:17082315   PMID:17332478   PMID:17881769   PMID:18214944  
PMID:18431520   PMID:18617680   PMID:19121317   PMID:19665600   PMID:19734214   PMID:20100971   PMID:20600022   PMID:20927330   PMID:20980401   PMID:21135503   PMID:21267068   PMID:21664343  
PMID:21688123   PMID:21789190   PMID:21873635   PMID:22180059   PMID:22253262   PMID:22523320   PMID:22682244   PMID:22715999   PMID:23852503   PMID:24223168   PMID:24297922   PMID:24519625  
PMID:25528766   PMID:25946003   PMID:25997509   PMID:26655736   PMID:28160627   PMID:28487027   PMID:28864002   PMID:29217821   PMID:29596938   PMID:30268501   PMID:30520693   PMID:31132747  
PMID:31415618   PMID:32656894   PMID:33082445   PMID:33462828   PMID:33863879   PMID:34108253   PMID:34239012   PMID:34350769   PMID:35408908   PMID:35803228   PMID:35906886   PMID:36154781  
PMID:36424386   PMID:36470928   PMID:36503802   PMID:36685040   PMID:36924234   PMID:37153732   PMID:37292200   PMID:37495078   PMID:37629170   PMID:37853428   PMID:37910094   PMID:38443404  
PMID:38679415   PMID:38758184   PMID:39020175   PMID:39128004   PMID:39294742   PMID:39358385  


Genomics

Comparative Map Data
Il11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,775,372 - 4,785,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,775,372 - 4,785,858 (-)EnsemblGRCm39 Ensembl
GRCm3874,772,373 - 4,782,907 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,772,373 - 4,782,859 (-)EnsemblGRCm38mm10GRCm38
MGSCv3774,724,657 - 4,729,743 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,376,142 - 4,381,118 (-)NCBIMGSCv36mm8
Celera74,502,811 - 4,507,897 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.76NCBI
IL11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,364,382 - 55,370,463 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,364,382 - 55,370,463 (-)EnsemblGRCh38hg38GRCh38
GRCh371955,875,750 - 55,881,831 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,567,569 - 60,573,626 (-)NCBINCBI36Build 36hg18NCBI36
Build 341960,567,568 - 60,573,626NCBI
Celera1952,916,561 - 52,922,599 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,197,803 - 52,203,675 (-)NCBIHuRef
CHM1_11955,869,294 - 55,875,375 (-)NCBICHM1_1
T2T-CHM13v2.01958,459,867 - 58,465,950 (-)NCBIT2T-CHM13v2.0
Il11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,098,622 - 78,104,915 (+)NCBIGRCr8
mRatBN7.2169,069,829 - 69,076,129 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,068,137 - 69,076,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,414,863 - 74,421,166 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,979,176 - 82,985,471 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,127,995 - 76,134,275 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,636,959 - 72,643,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,635,267 - 72,643,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,891,524 - 75,902,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,784,584 - 67,795,141 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,862,694 - 68,157,244 (+)NCBI
Celera168,048,383 - 68,054,698 (-)NCBICelera
Cytogenetic Map1q12NCBI
Il11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567871,489 - 883,563 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955567868,272 - 883,563 (+)NCBIChiLan1.0ChiLan1.0
IL11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,501,839 - 61,516,036 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,230,892 - 63,244,968 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,407,730 - 52,426,445 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,095,104 - 61,101,843 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,096,275 - 61,101,837 (-)Ensemblpanpan1.1panPan2
IL11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,311,960 - 102,319,102 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,316,105 - 102,318,653 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,368,701 - 102,375,810 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,965,197 - 102,972,306 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,965,691 - 102,972,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,602,478 - 102,609,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,314,584 - 102,321,607 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,077,747 - 103,084,856 (+)NCBIUU_Cfam_GSD_1.0
Il11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,937,446 - 1,941,716 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886618,419 - 621,772 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886617,531 - 620,661 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,541,213 - 59,544,896 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,540,482 - 59,544,909 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IL11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,967,245 - 47,972,557 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,967,680 - 47,971,316 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045601,368 - 607,368 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,933,179 - 1,935,971 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,932,959 - 1,936,937 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il11
490 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:252
Count of miRNA genes:155
Interacting mature miRNAs:161
Transcripts:ENSMUST00000094892, ENSMUST00000163481
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
25394570Skmw58_mskeletal muscle weight 58, TA (mouse)735524286281481Mouse
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
25394569Skmw57_mskeletal muscle weight 57, gastroc (mouse)7458046916687861Mouse
1302115Abhr3_mallergen-induced bronchial hyperresponsiveness 3 (mouse)Not determined7331599616637423Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse

Markers in Region
U03421  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3874,773,290 - 4,773,404UniSTSGRCm38
MGSCv3774,724,892 - 4,725,006UniSTSGRCm37
Celera74,503,046 - 4,503,160UniSTS
Cytogenetic Map7A1UniSTS
cM Map72.0UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Il11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A1UniSTS
cM Map72.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000094892   ⟹   ENSMUSP00000092492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl74,775,372 - 4,781,140 (-)Ensembl
GRCm38.p6 Ensembl74,772,373 - 4,778,141 (-)Ensembl
Ensembl Acc Id: ENSMUST00000163481   ⟹   ENSMUSP00000131168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl74,776,232 - 4,785,856 (-)Ensembl
GRCm38.p6 Ensembl74,773,233 - 4,782,857 (-)Ensembl
Ensembl Acc Id: ENSMUST00000234277   ⟹   ENSMUSP00000157240
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl74,776,232 - 4,785,858 (-)Ensembl
GRCm38.p6 Ensembl74,773,233 - 4,782,859 (-)Ensembl
RefSeq Acc Id: NM_001290423   ⟹   NP_001277352
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,785,858 (-)NCBI
GRCm3874,772,378 - 4,782,857 (-)NCBI
Celera74,502,134 - 4,512,614 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001412482   ⟹   NP_001399411
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,785,858 (-)NCBI
RefSeq Acc Id: NM_001412483   ⟹   NP_001399412
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,780,359 (-)NCBI
RefSeq Acc Id: NM_001412484   ⟹   NP_001399413
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,780,007 (-)NCBI
RefSeq Acc Id: NM_008350   ⟹   NP_032376
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,781,142 (-)NCBI
GRCm3874,772,378 - 4,778,141 (-)NCBI
MGSCv3774,724,657 - 4,729,743 (-)RGD
Celera74,502,134 - 4,512,614 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321988   ⟹   XP_017177477
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,776,051 - 4,785,877 (-)NCBI
GRCm3874,772,373 - 4,782,878 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152699   ⟹   XP_036008592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3974,775,372 - 4,785,382 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032376   ⟸   NM_008350
- Peptide Label: isoform 1 precursor
- UniProtKB: P47873 (UniProtKB/Swiss-Prot),   A3KPB8 (UniProtKB/TrEMBL),   Q3V0U3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277352   ⟸   NM_001290423
- Peptide Label: isoform 2
- UniProtKB: F7A7F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177477   ⟸   XM_017321988
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSMUSP00000131168   ⟸   ENSMUST00000163481
Ensembl Acc Id: ENSMUSP00000092492   ⟸   ENSMUST00000094892
Ensembl Acc Id: ENSMUSP00000157240   ⟸   ENSMUST00000234277
RefSeq Acc Id: XP_036008592   ⟸   XM_036152699
- Peptide Label: isoform X1
- UniProtKB: F7A7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399411   ⟸   NM_001412482
- Peptide Label: isoform 2
- UniProtKB: F7A7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399412   ⟸   NM_001412483
- Peptide Label: isoform 2
- UniProtKB: F7A7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399413   ⟸   NM_001412484
- Peptide Label: isoform 2
- UniProtKB: F7A7F2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47873-F1-model_v2 AlphaFold P47873 1-199 view protein structure

Promoters
RGD ID:6841323
Promoter ID:MM_KWN:48474
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:ENSMUST00000094892
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3674,728,981 - 4,729,481 (-)MPROMDB
RGD ID:6891712
Promoter ID:EPDNEW_M9307
Type:single initiation site
Name:Il11_1
Description:Mus musculus interleukin 11 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3874,778,143 - 4,778,203EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107613 AgrOrtholog
Ensembl Genes ENSMUSG00000004371 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000094892 ENTREZGENE
  ENSMUST00000094892.12 UniProtKB/Swiss-Prot
  ENSMUST00000163481 ENTREZGENE
  ENSMUST00000163481.3 UniProtKB/TrEMBL
  ENSMUST00000234277 ENTREZGENE
  ENSMUST00000234277.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-11_mml UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107613 ENTREZGENE
NCBI Gene 16156 ENTREZGENE
PANTHER INTERLEUKIN-11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16922 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il11 PhenoGen
PRINTS INTLKN11MAML UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKIN11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A3KPB8 ENTREZGENE, UniProtKB/TrEMBL
  F7A7F2 ENTREZGENE, UniProtKB/TrEMBL
  IL11_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V0U3 ENTREZGENE, UniProtKB/TrEMBL