Bach2 (BTB and CNC homology, basic leucine zipper transcription factor 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Bach2 (BTB and CNC homology, basic leucine zipper transcription factor 2) Mus musculus
Analyze
Symbol: Bach2
Name: BTB and CNC homology, basic leucine zipper transcription factor 2
RGD ID: 1621642
MGI Page MGI
Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in import into nucleus and negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including ganglia; limb bud; reproductive system; telencephalon; and urinary system. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BTB and CNC homolog 2; BTB and CNC homology 2; E030004N02Rik; MGC117590; RIKEN cDNA E030004N02 gene; transcription regulator protein BACH2; Transcription regulator protein BACH2 (BTB and CNC homolog 2)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,238,413 - 32,586,109 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm39 Ensembl
GRCm38432,238,413 - 32,586,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,504,410 - 32,673,083 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,567,563 - 32,909,812 (+)NCBIMGSCv36mm8
Celera432,164,289 - 32,333,354 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (ISO)
1,1-dichloroethene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-Zearalanol  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
buta-1,3-diene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
choline  (EXP)
chromium(3+) trichloride  (EXP)
clobetasol  (EXP)
cocaine  (EXP)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloromethane  (EXP)
Diisodecyl phthalate  (EXP)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
folic acid  (EXP)
gentamycin  (ISO)
ionomycin  (ISO)
isoflurane  (EXP)
L-methionine  (EXP)
lipopolysaccharide  (EXP)
methamphetamine  (EXP)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
ozone  (EXP)
paracetamol  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sotorasib  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (ISO)
thiram  (ISO)
trametinib  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell differentiation  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal bone structure  (IEA)
abnormal class switch recombination  (IAGP)
abnormal optic disk morphology  (IEA)
abnormal somatic hypermutation frequency  (IAGP)
absent germinal center B cells  (IAGP)
decreased B cell number  (IAGP)
decreased B-1a cell number  (IEA)
decreased B-2 B cell number  (IEA)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased CD11b-high dendritic cell number  (IEA)
decreased CD4-negative NK T cell number  (IEA)
decreased CD4-positive, alpha-beta T cell number  (IEA)
decreased CD8-positive, naive alpha-beta T cell number  (IEA)
decreased circulating creatinine level  (IEA)
decreased circulating glucose level  (IEA)
decreased effector memory CD8-positive, alpha-beta T cell number  (IEA)
decreased exploration in new environment  (IEA)
decreased follicular B cell number  (IEA)
decreased food intake  (IEA)
decreased IgA level  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IAGP)
decreased IgG2b level  (IAGP)
decreased IgG3 level  (IAGP)
decreased Ly6C-positive immature NK cell number  (IEA)
decreased Ly6C-positive mature NK cell number  (IEA)
decreased marginal zone B cell number  (IEA)
decreased mature B cell number  (IAGP)
decreased memory-marker CD4-negative NK T cell number  (IEA)
decreased memory-marker NK cell number  (IEA)
decreased NK T cell number  (IEA)
decreased prepulse inhibition  (IEA)
decreased regulatory T cell number  (IEA)
decreased respiratory quotient  (IEA)
decreased transitional stage B cell number  (IEA)
decreased vertical activity  (IEA)
hyperactivity  (IEA)
immune system phenotype  (IEA)
increased B-1 B cell number  (IEA)
increased CD103-positive CD11b-low dendritic cell number  (IEA)
increased CD11b-low dendritic cell number  (IEA)
increased CD4-positive, alpha-beta memory T cell number  (IEA)
increased CD8-positive, alpha-beta memory T cell number  (IEA)
increased circulating alkaline phosphatase level  (IEA)
increased circulating amylase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating iron level  (IEA)
increased circulating unsaturated transferrin level  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased effector memory T-helper cell number  (IEA)
increased eosinophil cell number  (IEA)
increased granulocyte number  (IEA)
increased grip strength  (IEA)
increased IgM level  (IAGP)
increased immature B cell number  (IEA)
increased KLRG1+ CD4 alpha-beta T cell number  (IEA)
increased KLRG1+ CD8 alpha-beta T cell number  (IEA)
increased KLRG1-positive CD4-negative NK T cell number  (IEA)
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased KLRG1-positive gamma-delta T cell number  (IEA)
increased KLRG1-positive NK cell number  (IEA)
increased Ly6C high monocyte number  (IEA)
increased Ly6C low monocyte number  (IEA)
increased macrophage cell number  (IEA)
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased memory-marker CD4-negative NK T cell number  (IEA)
increased memory-marker NK cell number  (IEA)
increased monocyte cell number  (IEA)
increased neutrophil cell number  (IEA)
increased NK cell number  (IEA)
increased NK T cell number  (IEA)
increased pulmonary respiratory rate  (IEA)
limb grasping  (IEA)
myeloid hyperplasia  (IEA)
short tibia  (IEA)
spleen hypoplasia  (IAGP)
thrombocytosis  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8887638   PMID:10349636   PMID:10669750   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11923289   PMID:12204112   PMID:12466851   PMID:12477932   PMID:12556477   PMID:15060166  
PMID:15152264   PMID:15618518   PMID:16141072   PMID:16141073   PMID:16331266   PMID:16631738   PMID:17046816   PMID:18287559   PMID:18799693   PMID:19159451   PMID:19170764   PMID:20412781  
PMID:20953163   PMID:21267068   PMID:21444915   PMID:21677750   PMID:21873635   PMID:22988430   PMID:23728300   PMID:23754397   PMID:23850379   PMID:23852341   PMID:24075570   PMID:24127487  
PMID:24200680   PMID:24277074   PMID:24316575   PMID:24367030   PMID:24694524   PMID:24952961   PMID:25043184   PMID:25344725   PMID:25444856   PMID:25857523   PMID:25998054   PMID:26021350  
PMID:26522720   PMID:26590946   PMID:26620562   PMID:26731475   PMID:26786103   PMID:27158840   PMID:27158841   PMID:27387751   PMID:27480124   PMID:27581382   PMID:27899360   PMID:28213137  
PMID:28216546   PMID:28273455   PMID:28530713   PMID:28592433   PMID:28855027   PMID:28916727   PMID:28993481   PMID:29514092   PMID:29540581   PMID:29625895   PMID:30089837   PMID:30250186  
PMID:30459773   PMID:30833348   PMID:30971440   PMID:30973865   PMID:31451674   PMID:31552021   PMID:31819031   PMID:31937752   PMID:32245826   PMID:32325033   PMID:32515782   PMID:33382975  
PMID:33574619   PMID:33979619   PMID:34321999   PMID:34389622   PMID:34474245   PMID:35513721   PMID:35716600   PMID:35793628   PMID:36033397   PMID:36086884   PMID:36105283   PMID:36178457  
PMID:36190189   PMID:36542062   PMID:36577384   PMID:37858463   PMID:37888952   PMID:38355793   PMID:38605225  


Genomics

Comparative Map Data
Bach2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,238,413 - 32,586,109 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm39 Ensembl
GRCm38432,238,413 - 32,586,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,504,410 - 32,673,083 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,567,563 - 32,909,812 (+)NCBIMGSCv36mm8
Celera432,164,289 - 32,333,354 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.02NCBI
BACH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,926,528 - 90,296,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,926,528 - 90,296,843 (-)EnsemblGRCh38hg38GRCh38
GRCh37690,636,247 - 91,006,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,692,969 - 91,063,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 34690,692,968 - 91,063,182NCBI
Celera691,056,791 - 91,427,144 (-)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,855,580 - 88,225,476 (-)NCBIHuRef
CHM1_1690,733,911 - 91,104,124 (-)NCBICHM1_1
T2T-CHM13v2.0691,138,217 - 91,508,429 (-)NCBIT2T-CHM13v2.0
Bach2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,428,802 - 51,779,030 (+)NCBIGRCr8
mRatBN7.2546,632,338 - 46,982,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl546,638,317 - 46,977,877 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx548,859,726 - 49,119,822 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,458,890 - 50,718,988 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,402,412 - 50,664,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,458,891 - 47,807,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,546,014 - 47,807,166 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,073,295 - 52,410,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,611,805 - 48,881,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera545,479,904 - 45,738,863 (+)NCBICelera
Cytogenetic Map5q21NCBI
Bach2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541116,613,397 - 16,877,834 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541116,607,546 - 16,947,359 (-)NCBIChiLan1.0ChiLan1.0
BACH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25110,011,721 - 110,381,491 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,912,858 - 108,282,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,806,188 - 88,175,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1691,081,381 - 91,212,497 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl691,083,533 - 91,160,552 (-)Ensemblpanpan1.1panPan2
BACH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,101,621 - 49,375,415 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,106,523 - 49,460,286 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,908,403 - 49,267,597 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,910,921 - 50,270,587 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,916,822 - 50,270,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,225,818 - 49,503,613 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,126,581 - 49,485,448 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,318,946 - 49,677,611 (-)NCBIUU_Cfam_GSD_1.0
Bach2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,094,552 - 84,429,900 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,299,831 - 2,371,544 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,041,004 - 2,375,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BACH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,899,808 - 58,281,430 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,881,203 - 58,281,740 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,904,041 - 65,200,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BACH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,681,323 - 15,049,690 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,687,188 - 14,763,706 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040191,077,385 - 191,445,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bach2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247993,984,546 - 4,256,898 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247993,893,548 - 4,262,344 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bach2
11321 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5762
Count of miRNA genes:908
Interacting mature miRNAs:1251
Transcripts:ENSMUST00000037416, ENSMUST00000108180, ENSMUST00000125263, ENSMUST00000146748, ENSMUST00000149201, ENSMUST00000156430, ENSMUST00000171600
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
12903995Opfaq2_mopen field activity QTL 2 (mouse)43034341933824057Mouse

Markers in Region
MTH2266  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38432,287,965 - 32,288,075UniSTSGRCm38
MGSCv37432,374,940 - 32,375,050UniSTSGRCm37
Celera432,033,280 - 32,033,390UniSTS
Whitehead_YAC4 UniSTS
D4Mit267  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38432,282,644 - 32,282,758UniSTSGRCm38
MGSCv37432,369,619 - 32,369,733UniSTSGRCm37
Celera432,027,979 - 32,028,093UniSTS
cM Map47.5UniSTS
Whitehead Genetic412.0UniSTS
Whitehead/MRC_RH4538.79UniSTS
Whitehead_YAC4 UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK047850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ092609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX200493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY467972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000037416   ⟹   ENSMUSP00000043693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,238,950 - 32,581,199 (+)Ensembl
GRCm38.p6 Ensembl432,238,950 - 32,581,199 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108180   ⟹   ENSMUSP00000103815
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,238,804 - 32,586,104 (+)Ensembl
GRCm38.p6 Ensembl432,238,804 - 32,586,104 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125263
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,574,931 - 32,579,838 (+)Ensembl
GRCm38.p6 Ensembl432,574,931 - 32,579,838 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,501,505 - 32,502,626 (+)Ensembl
GRCm38.p6 Ensembl432,501,505 - 32,502,626 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149201
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,239,077 - 32,501,636 (+)Ensembl
GRCm38.p6 Ensembl432,239,077 - 32,501,636 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,247,764 - 32,317,229 (+)Ensembl
GRCm38.p6 Ensembl432,247,764 - 32,317,229 (+)Ensembl
Ensembl Acc Id: ENSMUST00000171600   ⟹   ENSMUSP00000131592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,417,435 - 32,586,108 (+)Ensembl
GRCm38.p6 Ensembl432,417,435 - 32,586,108 (+)Ensembl
RefSeq Acc Id: NM_001109661   ⟹   NP_001103131
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,417,435 - 32,586,108 (+)NCBI
GRCm38432,417,435 - 32,586,108 (+)NCBI
MGSCv37432,504,410 - 32,673,083 (+)RGD
Celera432,164,289 - 32,333,354 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006537566   ⟹   XP_006537629
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,574 - 32,586,109 (+)NCBI
GRCm38432,238,441 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006537567   ⟹   XP_006537630
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,417,610 - 32,586,109 (+)NCBI
GRCm38432,417,608 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249908   ⟹   XP_011248210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,539 - 32,586,109 (+)NCBI
GRCm38432,238,441 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249909   ⟹   XP_011248211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,413 - 32,586,109 (+)NCBI
GRCm38432,238,413 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249910   ⟹   XP_011248212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,561,420 - 32,586,109 (+)NCBI
GRCm38432,561,425 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030253109   ⟹   XP_030108969
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,574 - 32,586,109 (+)NCBI
GRCm38432,238,441 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030253112   ⟹   XP_030108972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,480 - 32,586,109 (+)NCBI
GRCm38432,238,441 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163607   ⟹   XP_036019500
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,574 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163608   ⟹   XP_036019501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,238,574 - 32,586,109 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001103131   ⟸   NM_001109661
- UniProtKB: A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot),   P97303 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006537629   ⟸   XM_006537566
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006537630   ⟸   XM_006537567
- Peptide Label: isoform X2
- UniProtKB: A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot),   P97303 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011248211   ⟸   XM_011249909
- Peptide Label: isoform X2
- UniProtKB: A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot),   P97303 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011248210   ⟸   XM_011249908
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011248212   ⟸   XM_011249910
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_030108972   ⟸   XM_030253112
- Peptide Label: isoform X2
- UniProtKB: P97303 (UniProtKB/Swiss-Prot),   A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030108969   ⟸   XM_030253109
- Peptide Label: isoform X1
Ensembl Acc Id: ENSMUSP00000103815   ⟸   ENSMUST00000108180
Ensembl Acc Id: ENSMUSP00000131592   ⟸   ENSMUST00000171600
Ensembl Acc Id: ENSMUSP00000043693   ⟸   ENSMUST00000037416
RefSeq Acc Id: XP_036019500   ⟸   XM_036163607
- Peptide Label: isoform X2
- UniProtKB: P97303 (UniProtKB/Swiss-Prot),   A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036019501   ⟸   XM_036163608
- Peptide Label: isoform X2
- UniProtKB: P97303 (UniProtKB/Swiss-Prot),   A2ANU9 (UniProtKB/Swiss-Prot),   A2ANU8 (UniProtKB/Swiss-Prot),   A2RRI0 (UniProtKB/Swiss-Prot)
Protein Domains
BTB   bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97303-F1-model_v2 AlphaFold P97303 1-839 view protein structure

Promoters
RGD ID:6882958
Promoter ID:EPDNEW_M4930
Type:initiation region
Name:Bach2_1
Description:Mus musculus BTB and CNC homology, basic leucine zipper transcriptionfactor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4931  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38432,238,897 - 32,238,957EPDNEW
RGD ID:6834936
Promoter ID:MM_KWN:36955
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung
Transcripts:ENSMUST00000037416,   NM_007521,   OTTMUST00000010964,   OTTMUST00000010966
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36432,325,591 - 32,326,242 (+)MPROMDB
RGD ID:6834937
Promoter ID:MM_KWN:36957
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:OTTMUST00000010967
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36432,333,911 - 32,334,411 (+)MPROMDB
RGD ID:6882960
Promoter ID:EPDNEW_M4931
Type:single initiation site
Name:Bach2_2
Description:Mus musculus BTB and CNC homology, basic leucine zipper transcriptionfactor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4930  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38432,463,649 - 32,463,709EPDNEW
RGD ID:6834935
Promoter ID:MM_KWN:36964
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:AK086854_E030004N02RIK
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36432,672,251 - 32,672,751 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:894679 AgrOrtholog
Ensembl Genes ENSMUSG00000040270 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037416.13 UniProtKB/Swiss-Prot
  ENSMUST00000108180 ENTREZGENE
  ENSMUST00000108180.9 UniProtKB/Swiss-Prot
  ENSMUST00000171600 ENTREZGENE
  ENSMUST00000171600.2 UniProtKB/Swiss-Prot
Gene3D-CATH Transcription factor, Skn-1-like, DNA-binding domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_BACH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnFinger_BTB_dom_contain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12014 UniProtKB/Swiss-Prot
MGD MGI:894679 ENTREZGENE
NCBI Gene 12014 ENTREZGENE
PANTHER AGAP004733-PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION REGULATOR PROTEIN BACH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bach2 PhenoGen
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ANU8 ENTREZGENE
  A2ANU9 ENTREZGENE
  A2RRI0 ENTREZGENE
  BACH2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TSF4_MOUSE UniProtKB/TrEMBL
  Q4KL56_MOUSE UniProtKB/TrEMBL
  Q80WG0_MOUSE UniProtKB/TrEMBL
UniProt Secondary A2ANU8 UniProtKB/Swiss-Prot
  A2ANU9 UniProtKB/Swiss-Prot
  A2RRI0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Bach2  BTB and CNC homology, basic leucine zipper transcription factor 2  E030004N02Rik  RIKEN cDNA E030004N02 gene  Data merged from RGD:1612834 737654 PROVISIONAL
2015-12-22 Bach2  BTB and CNC homology, basic leucine zipper transcription factor 2    BTB and CNC homology 2  Symbol and/or name change 5135510 APPROVED