Nox4 (NADPH oxidase 4) - Rat Genome Database

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Gene: Nox4 (NADPH oxidase 4) Mus musculus
Analyze
Symbol: Nox4
Name: NADPH oxidase 4
RGD ID: 731543
MGI Page MGI
Description: Enables protein tyrosine kinase binding activity and superoxide-generating NAD(P)H oxidase activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of intracellular signal transduction; and superoxide anion generation. Acts upstream of or within bone resorption and cardiac muscle cell differentiation. Located in cell periphery; mitochondrion; and perinuclear region of cytoplasm. Is expressed in embryo; heart; metanephros; renal cortex; and ventricle compact myocardium. Orthologous to human NOX4 (NADPH oxidase 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI648021; kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX-1; renal NAD(P)H-oxidase; superoxide-generating NADPH oxidase 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39786,893,638 - 87,047,918 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl786,895,304 - 87,047,918 (+)EnsemblGRCm39 Ensembl
GRCm38787,244,430 - 87,398,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl787,246,096 - 87,398,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv37794,395,305 - 94,547,116 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36787,122,556 - 87,274,367 (+)NCBIMGSCv36mm8
Celera784,613,741 - 84,757,901 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R)-lipoic acid  (EXP,ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
1,4-bis(2-ethylhexyl) sulfosuccinate  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
agomelatine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-D-galactose  (ISO)
amitrole  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
amsacrine  (ISO)
angiotensin II  (EXP,ISO)
antirheumatic drug  (ISO)
apocynin  (ISO)
aristolochic acid A  (EXP,ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (ISO)
atorvastatin calcium  (ISO)
aucubin  (EXP,ISO)
bellidifolin  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bezafibrate  (EXP,ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
bosentan  (ISO)
bromobenzene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium oxalate  (ISO)
candesartan  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carteolol  (ISO)
carvacrol  (ISO)
CGP-42112A  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium atom  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
colistin  (EXP,ISO)
corosolic acid  (EXP)
crocidolite asbestos  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (EXP)
cytarabine  (ISO)
D-glucose  (ISO)
dapsone  (EXP,ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
Deoxycorticosterone acetate  (EXP)
dexamethasone  (EXP)
dextran sulfate  (EXP)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenziodolium  (ISO)
dichloroacetic acid  (EXP)
dihydrogen  (EXP)
dioxygen  (EXP,ISO)
diprotium  (EXP)
doxorubicin  (EXP,ISO)
doxycycline  (EXP)
elemental selenium  (EXP)
endosulfan  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (ISO)
farrerol  (ISO)
fenthion  (EXP)
ferric oxide  (EXP)
fisetin  (ISO)
flavonoids  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fructose  (ISO)
furan  (ISO)
galactose  (ISO)
ginkgolide B  (EXP)
glucose  (ISO)
glutathione  (EXP)
glyoxylic acid  (ISO)
GW 6471  (ISO)
hesperetin  (EXP,ISO)
homocysteine  (ISO)
hydrazine  (EXP)
hydrochlorothiazide  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroxylamine  (ISO)
Ile(5)-angiotensin II  (EXP,ISO)
indoxyl sulfate  (ISO)
inulin  (EXP)
isoprenaline  (EXP,ISO)
kaempferol  (ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (EXP)
lanthanum trichloride  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(II) chloride  (ISO)
Leonurine  (EXP,ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
liraglutide  (EXP)
loganin  (EXP)
lutein  (EXP)
LY294002  (ISO)
mancozeb  (EXP)
manidipine  (ISO)
melatonin  (ISO)
menadione  (EXP)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methyl vanillate  (ISO)
microcystin-LR  (EXP,ISO)
mitogen  (ISO)
monocrotaline  (ISO)
Morroniside  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naringin  (ISO)
nicotinamide  (ISO)
nicotine  (EXP)
nicotinic acid  (ISO)
nitroglycerin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PD123319  (EXP)
perfluorohexanesulfonic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
phosphatidylcholine  (ISO)
pioglitazone  (ISO)
pirfenidone  (EXP)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium iodide  (ISO)
probenecid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
salubrinal  (EXP)
saxagliptin  (ISO)
SB 203580  (ISO)
selenium atom  (EXP)
sevoflurane  (ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sirtinol  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
superoxide  (ISO)
telmisartan  (ISO)
teprenone  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thioacetamide  (ISO)
thymoquinone  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trans-piceid  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
troglitazone  (EXP)
tyrphostin AG 1478  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
venetoclax  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Cowley AW Jr, etal., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.
2. The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. Gojo A, etal., Eur J Pharmacol. 2007 Jul 30;568(1-3):242-7. Epub 2007 Apr 20.
3. Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. Gorin Y, etal., J Biol Chem. 2005 Nov 25;280(47):39616-26. Epub 2005 Aug 31.
4. Spinal Cord Injury Leads to Hyperoxidation and Nitrosylation of Skeletal Muscle Ryanodine Receptor-1 Associated with Upregulation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4. Liu XH, etal., J Neurotrauma. 2017 Jun 15;34(12):2069-2074. doi: 10.1089/neu.2016.4763. Epub 2017 Feb 27.
5. Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. Matsunami T, etal., Int J Clin Exp Pathol. 2010 May 22;3(5):472-81.
6. Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats. McCann SK, etal., J Neurosci Res. 2008 Aug 15;86(11):2524-34.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats. Nakamura M, etal., J Toxicol Sci. 2018;43(10):611-621. doi: 10.2131/jts.43.611.
9. The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice. Nisbet RE, etal., Am J Respir Cell Mol Biol. 2009 May;40(5):601-9. Epub 2008 Oct 23.
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats. Saha S, etal., Can J Physiol Pharmacol. 2008 Apr;86(4):190-8.
16. Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats. Tada Y, etal., Hypertension. 2009 Sep;54(3):552-7. Epub 2009 Jul 20.
17. Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia. Vallet P, etal., Neuroscience. 2005;132(2):233-8.
18. Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin. Wang C, etal., Eur J Pharmacol. 2009 Oct 12;620(1-3):131-7. Epub 2009 Aug 15.
19. Upregulation of Nox4 promotes angiotensin II-induced epidermal growth factor receptor activation and subsequent cardiac hypertrophy by increasing ADAM17 expression. Zeng SY, etal., Can J Cardiol. 2013 Oct;29(10):1310-9. doi: 10.1016/j.cjca.2013.04.026. Epub 2013 Jul 11.
Additional References at PubMed
PMID:10349636   PMID:10869423   PMID:11032835   PMID:11042159   PMID:11050424   PMID:11076861   PMID:11098048   PMID:11217851   PMID:12477932   PMID:12855428   PMID:14551238   PMID:15016652  
PMID:15108351   PMID:15489334   PMID:15638999   PMID:16141072   PMID:16141073   PMID:16537572   PMID:16775014   PMID:17292348   PMID:17443690   PMID:17553579   PMID:17568784   PMID:17585072  
PMID:17942966   PMID:18417717   PMID:18431508   PMID:18440230   PMID:18467643   PMID:18554521   PMID:19005069   PMID:19036941   PMID:19057021   PMID:19204183   PMID:19471020   PMID:19542021  
PMID:19701206   PMID:19817625   PMID:19925862   PMID:20185797   PMID:20224597   PMID:20228065   PMID:20300111   PMID:20363222   PMID:20413786   PMID:20427574   PMID:20493939   PMID:20606471  
PMID:20630933   PMID:20686447   PMID:20713697   PMID:20861022   PMID:20877473   PMID:20877715   PMID:20921387   PMID:20952384   PMID:21029048   PMID:21212270   PMID:21217672   PMID:21267068  
PMID:21343298   PMID:21391892   PMID:21415386   PMID:21513813   PMID:21554947   PMID:21788590   PMID:21873635   PMID:21896730   PMID:21935366   PMID:22031853   PMID:22095986   PMID:22328777  
PMID:22337127   PMID:22401855   PMID:22456182   PMID:22618020   PMID:22749956   PMID:22824863   PMID:22836249   PMID:22844079   PMID:22875785   PMID:22896039   PMID:22920224   PMID:22933115  
PMID:23049784   PMID:23100220   PMID:23152062   PMID:23216904   PMID:23261430   PMID:23271793   PMID:23329835   PMID:23393389   PMID:23413427   PMID:23476056   PMID:23503725   PMID:23564668  
PMID:23589292   PMID:23612968   PMID:23624625   PMID:23678045   PMID:23749776   PMID:23751520   PMID:23825363   PMID:23832701   PMID:23839498   PMID:23863470   PMID:23884197   PMID:23933064  
PMID:24051369   PMID:24081881   PMID:24205282   PMID:24213612   PMID:24216508   PMID:24259511   PMID:24285500   PMID:24324142   PMID:24371139   PMID:24432311   PMID:24466344   PMID:24482376  
PMID:24497637   PMID:24511132   PMID:24657416   PMID:24718857   PMID:24936437   PMID:24947524   PMID:25038307   PMID:25116588   PMID:25152242   PMID:25229402   PMID:25315297   PMID:25336743  
PMID:25410908   PMID:25450615   PMID:25534702   PMID:25589557   PMID:25646414   PMID:25652847   PMID:25701705   PMID:25866826   PMID:25982278   PMID:26036345   PMID:26054376   PMID:26083642  
PMID:26196532   PMID:26222337   PMID:26231202   PMID:26237157   PMID:26297224   PMID:26408539   PMID:26412187   PMID:26445208   PMID:26508318   PMID:26513738   PMID:26565025   PMID:26572549  
PMID:26582463   PMID:26661159   PMID:26689330   PMID:26715682   PMID:26731985   PMID:26742780   PMID:26812119   PMID:26861875   PMID:26908870   PMID:26945079   PMID:26952102   PMID:27140231  
PMID:27190136   PMID:27212017   PMID:27221536   PMID:27399878   PMID:27445103   PMID:27525436   PMID:27556956   PMID:27576730   PMID:27729244   PMID:27797149   PMID:27835780   PMID:27856286  
PMID:27912196   PMID:27924932   PMID:27941951   PMID:27986445   PMID:27989748   PMID:28038425   PMID:28049732   PMID:28062482   PMID:28062496   PMID:28062507   PMID:28152080   PMID:28165467  
PMID:28167773   PMID:28185955   PMID:28188286   PMID:28249219   PMID:28383062   PMID:28389561   PMID:28515175   PMID:28743960   PMID:28751569   PMID:28890346   PMID:28917508   PMID:29040462  
PMID:29085012   PMID:29087944   PMID:29106395   PMID:29113787   PMID:29391196   PMID:29471108   PMID:29540651   PMID:29561836   PMID:29587244   PMID:29653963   PMID:29674975   PMID:29675997  
PMID:29734661   PMID:29793963   PMID:29851084   PMID:29854821   PMID:29875323   PMID:30055798   PMID:30361098   PMID:30450923   PMID:30452880   PMID:30464227   PMID:30470772   PMID:30504729  
PMID:30528855   PMID:30578820   PMID:30589411   PMID:30610956   PMID:30707921   PMID:30726115   PMID:30755476   PMID:30816428   PMID:30938680   PMID:30967259   PMID:31037153   PMID:31117291  
PMID:31178956   PMID:31247506   PMID:31292433   PMID:31308397   PMID:31419440   PMID:31419754   PMID:31465542   PMID:31491600   PMID:31664454   PMID:31800011   PMID:31821410   PMID:31882567  
PMID:31898747   PMID:31919083   PMID:32000567   PMID:32051831   PMID:32083022   PMID:32143149   PMID:32213546   PMID:32245800   PMID:32325033   PMID:32329577   PMID:32438638   PMID:32441762  
PMID:32483169   PMID:32506037   PMID:32544088   PMID:32555397   PMID:32662486   PMID:32803108   PMID:32863203   PMID:32936698   PMID:33001475   PMID:33010578   PMID:33052238   PMID:33059312  
PMID:33079994   PMID:33086058   PMID:33201372   PMID:33267663   PMID:33278514   PMID:33279617   PMID:33376577   PMID:33400973   PMID:33418110   PMID:33493901   PMID:33504419   PMID:33511759  
PMID:33513310   PMID:33537085   PMID:33744854   PMID:33774476   PMID:33789124   PMID:33836590   PMID:34023385   PMID:34072916   PMID:34198827   PMID:34218201   PMID:34298093   PMID:34416105  
PMID:34523690   PMID:34530693   PMID:34656824   PMID:34910515   PMID:34922273   PMID:34930338   PMID:34949550   PMID:35346198   PMID:35348887   PMID:35378363   PMID:35504386   PMID:35601109  
PMID:35617030   PMID:35701603   PMID:35775122   PMID:35832027   PMID:35836253   PMID:35920301   PMID:36072988   PMID:36278481   PMID:36321558   PMID:36321974   PMID:36336227   PMID:36436728  
PMID:36708644   PMID:36709665   PMID:36732747   PMID:36738798   PMID:36762617   PMID:36810185   PMID:36950748   PMID:37002575   PMID:37044213   PMID:37058998   PMID:37159852   PMID:37207801  
PMID:37272080   PMID:37608820   PMID:37666363   PMID:37807310   PMID:37871532   PMID:37875930   PMID:38060313   PMID:38086768   PMID:38104863   PMID:38281712   PMID:38318360   PMID:38355793  
PMID:38690939   PMID:38748682   PMID:38776855   PMID:38910308   PMID:38920138  


Genomics

Comparative Map Data
Nox4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39786,893,638 - 87,047,918 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl786,895,304 - 87,047,918 (+)EnsemblGRCm39 Ensembl
GRCm38787,244,430 - 87,398,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl787,246,096 - 87,398,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv37794,395,305 - 94,547,116 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36787,122,556 - 87,274,367 (+)NCBIMGSCv36mm8
Celera784,613,741 - 84,757,901 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.96NCBI
NOX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,324,353 - 89,589,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,324,353 - 89,498,187 (-)EnsemblGRCh38hg38GRCh38
GRCh371189,057,521 - 89,322,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361188,699,160 - 88,864,301 (-)NCBINCBI36Build 36hg18NCBI36
Build 341188,699,159 - 88,864,301NCBI
Celera1185,399,612 - 85,574,418 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBIHuRef
CHM1_11188,940,465 - 89,205,767 (-)NCBICHM1_1
T2T-CHM13v2.01189,244,014 - 89,509,286 (-)NCBIT2T-CHM13v2.0
Nox4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,313,736 - 150,491,480 (+)NCBIGRCr8
mRatBN7.21140,900,886 - 141,078,844 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1140,901,097 - 141,077,406 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1148,877,339 - 149,042,590 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01156,047,993 - 156,213,233 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01148,921,890 - 149,087,126 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01150,796,359 - 150,976,186 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1150,797,084 - 150,976,194 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01157,106,652 - 157,196,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01157,246,099 - 157,285,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41143,415,816 - 143,603,554 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11143,494,221 - 143,681,960 (+)NCBI
Celera1139,242,883 - 139,407,667 (+)NCBICelera
Cytogenetic Map1q32NCBI
Nox4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554144,062,081 - 4,212,746 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554144,062,337 - 4,220,032 (+)NCBIChiLan1.0ChiLan1.0
NOX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,148,233 - 90,362,455 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11191,239,494 - 91,406,480 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01184,330,362 - 84,496,755 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11187,911,335 - 88,171,535 (-)NCBIpanpan1.1PanPan1.1panPan2
NOX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,615,153 - 10,782,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2110,615,970 - 10,775,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2110,465,855 - 10,632,710 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02110,796,288 - 10,963,304 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2110,795,550 - 10,960,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12110,584,756 - 10,745,644 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,643,276 - 10,811,261 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,699,999 - 10,861,437 (+)NCBIUU_Cfam_GSD_1.0
Nox4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494774,947,435 - 75,112,097 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936736230,476 - 396,708 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936736230,465 - 394,859 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl922,624,212 - 22,776,534 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1922,622,105 - 22,776,691 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2925,234,530 - 25,427,884 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1180,470,418 - 80,642,513 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl180,470,826 - 80,642,722 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604345,091,781 - 45,259,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nox4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624845669,902 - 827,834 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624845669,880 - 829,471 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nox4
6263 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2442
Count of miRNA genes:617
Interacting mature miRNAs:727
Transcripts:ENSMUST00000032781, ENSMUST00000068829, ENSMUST00000124057, ENSMUST00000124269, ENSMUST00000126887, ENSMUST00000127138, ENSMUST00000136577, ENSMUST00000144267
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226792Feml7_mfemur length 7, 5 week (mouse)78614920898949207Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse

Markers in Region
AI648021  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38787,398,210 - 87,398,319UniSTSGRCm38
MGSCv37794,546,720 - 94,546,829UniSTSGRCm37
Celera784,757,505 - 84,757,614UniSTS
Cytogenetic Map7D3UniSTS
Whitehead/MRC_RH7920.26UniSTS
g6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7D3UniSTS
Nox4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7D3UniSTS
cM Map7 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001285833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB041034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB042745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC141329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF218723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF261944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF276957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY001994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ227847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU861989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032781   ⟹   ENSMUSP00000032781
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,895,857 - 87,047,918 (+)Ensembl
GRCm38.p6 Ensembl787,246,649 - 87,398,710 (+)Ensembl
Ensembl Acc Id: ENSMUST00000068829   ⟹   ENSMUSP00000070039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,896,003 - 87,045,071 (+)Ensembl
GRCm38.p6 Ensembl787,246,795 - 87,395,863 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124057   ⟹   ENSMUSP00000119365
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,895,304 - 86,954,074 (+)Ensembl
GRCm38.p6 Ensembl787,246,096 - 87,304,866 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124269
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,895,857 - 86,937,189 (+)Ensembl
GRCm38.p6 Ensembl787,246,649 - 87,287,981 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126887   ⟹   ENSMUSP00000138336
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,895,857 - 87,047,918 (+)Ensembl
GRCm38.p6 Ensembl787,246,649 - 87,398,710 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127138
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,895,857 - 86,957,420 (+)Ensembl
GRCm38.p6 Ensembl787,246,649 - 87,308,212 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136577   ⟹   ENSMUSP00000138274
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,896,003 - 87,041,562 (+)Ensembl
GRCm38.p6 Ensembl787,246,795 - 87,392,354 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144267   ⟹   ENSMUSP00000138143
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl786,896,020 - 87,047,548 (+)Ensembl
GRCm38.p6 Ensembl787,246,812 - 87,398,340 (+)Ensembl
RefSeq Acc Id: NM_001285833   ⟹   NP_001272762
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,895,857 - 87,047,918 (+)NCBI
GRCm38787,246,649 - 87,398,710 (+)NCBI
Celera784,613,595 - 84,758,005 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001285835   ⟹   NP_001272764
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,895,857 - 87,047,918 (+)NCBI
GRCm38787,246,649 - 87,398,710 (+)NCBI
Celera784,613,595 - 84,758,005 (+)NCBI
Sequence:
RefSeq Acc Id: NM_015760   ⟹   NP_056575
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,895,857 - 87,047,918 (+)NCBI
GRCm38787,246,649 - 87,398,710 (+)NCBI
MGSCv37794,395,305 - 94,547,116 (+)RGD
Celera784,613,595 - 84,758,005 (+)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006508010   ⟹   XP_006508073
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,896,428 - 87,047,918 (+)NCBI
GRCm38787,246,909 - 87,398,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508011   ⟹   XP_006508074
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,893,638 - 86,980,948 (+)NCBI
GRCm38787,244,430 - 87,331,740 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508012   ⟹   XP_006508075
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,893,638 - 87,047,918 (+)NCBI
GRCm38787,244,430 - 87,398,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322347   ⟹   XP_017177836
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,893,638 - 87,047,918 (+)NCBI
GRCm38787,244,430 - 87,398,710 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934139
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39786,893,638 - 87,047,918 (+)NCBI
Sequence:
RefSeq Acc Id: NP_056575   ⟸   NM_015760
- Peptide Label: isoform 1
- UniProtKB: Q8C3M1 (UniProtKB/Swiss-Prot),   Q3TF39 (UniProtKB/Swiss-Prot),   Q8VCA3 (UniProtKB/Swiss-Prot),   Q9JHI8 (UniProtKB/Swiss-Prot),   B2RSM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272762   ⟸   NM_001285833
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_001272764   ⟸   NM_001285835
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: XP_006508075   ⟸   XM_006508012
- Peptide Label: isoform X4
- UniProtKB: Q9JHI8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006508074   ⟸   XM_006508011
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006508073   ⟸   XM_006508010
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017177836   ⟸   XM_017322347
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000032781   ⟸   ENSMUST00000032781
Ensembl Acc Id: ENSMUSP00000119365   ⟸   ENSMUST00000124057
Ensembl Acc Id: ENSMUSP00000138143   ⟸   ENSMUST00000144267
Ensembl Acc Id: ENSMUSP00000070039   ⟸   ENSMUST00000068829
Ensembl Acc Id: ENSMUSP00000138336   ⟸   ENSMUST00000126887
Ensembl Acc Id: ENSMUSP00000138274   ⟸   ENSMUST00000136577
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHI8-F1-model_v2 AlphaFold Q9JHI8 1-578 view protein structure

Promoters
RGD ID:8664701
Promoter ID:EPDNEW_M10382
Type:initiation region
Name:Nox4_2
Description:Mus musculus NADPH oxidase 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10383  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38787,246,659 - 87,246,719EPDNEW
RGD ID:8664703
Promoter ID:EPDNEW_M10383
Type:multiple initiation site
Name:Nox4_1
Description:Mus musculus NADPH oxidase 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10382  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38787,246,795 - 87,246,855EPDNEW
RGD ID:6841687
Promoter ID:MM_KWN:51464
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   ES_Cell,   Kidney,   MEF_B4
Transcripts:ENSMUST00000043406,   OTTMUST00000050047,   OTTMUST00000050048,   OTTMUST00000050049,   OTTMUST00000050050,   OTTMUST00000050051,   OTTMUST00000050052,   OTTMUST00000050053,   UC009IFM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36794,394,991 - 94,395,491 (+)MPROMDB
RGD ID:6849230
Promoter ID:MM_XEF:6661
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_001131440,   NM_001143837
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36794,395,201 - 94,395,701 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354184 AgrOrtholog
Ensembl Genes ENSMUSG00000030562 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032781 ENTREZGENE
  ENSMUST00000032781.14 UniProtKB/Swiss-Prot
  ENSMUST00000068829.13 UniProtKB/Swiss-Prot
  ENSMUST00000124057.8 UniProtKB/TrEMBL
  ENSMUST00000126887.8 UniProtKB/TrEMBL
  ENSMUST00000136577.9 UniProtKB/TrEMBL
  ENSMUST00000144267.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_b245_heavy_chain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fe3_Rdtase_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fe_red_NAD-bd_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBOH/FRE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1354184 ENTREZGENE
NCBI Gene 50490 ENTREZGENE
PANTHER NADPH OXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADPH OXIDASE 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAD_binding_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferric_reduct UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nox4 PhenoGen
PRINTS GP91PHOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RSM1 ENTREZGENE, UniProtKB/TrEMBL
  B5AN18_MOUSE UniProtKB/TrEMBL
  D3Z2E1_MOUSE UniProtKB/TrEMBL
  NOX4_MOUSE UniProtKB/Swiss-Prot
  Q3TF39 ENTREZGENE
  Q8C3M1 ENTREZGENE
  Q8VCA3 ENTREZGENE
  Q9JHI8 ENTREZGENE
  S4R1R3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TF39 UniProtKB/Swiss-Prot
  Q8C3M1 UniProtKB/Swiss-Prot
  Q8VCA3 UniProtKB/Swiss-Prot