Tlr4 (toll-like receptor 4) - Rat Genome Database

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Gene: Tlr4 (toll-like receptor 4) Mus musculus
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Symbol: Tlr4
Name: toll-like receptor 4
RGD ID: 737014
MGI Page MGI
Description: Enables lipopolysaccharide immune receptor activity. Involved in several processes, including regulation of cytokine production; response to lipopolysaccharide; and toll-like receptor signaling pathway. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; regulation of cytokine production; and response to bacterium. Located in plasma membrane. Part of receptor complex. Is expressed in brain; early embryo; genitourinary system; inner cell mass; and intestine. Used to study pulmonary emphysema. Human ortholog(s) of this gene implicated in several diseases, including allergic contact dermatitis (multiple); artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Orthologous to human TLR4 (toll like receptor 4).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: lipopolysaccharide response; Lps; Ly87; Ran/M1; Ras; Rasl2-8; Toll like receptor 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39466,745,788 - 66,765,338 (+)NCBIGRCm39mm39
GRCm39 Ensembl466,745,821 - 66,848,521 (+)Ensembl
GRCm38466,827,551 - 66,846,581 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl466,827,584 - 66,930,284 (+)EnsemblGRCm38mm10GRCm38
MGSCv37466,488,845 - 66,503,831 (+)NCBIGRCm37mm9NCBIm37
MGSCv36466,314,172 - 66,329,158 (+)NCBImm8
Celera465,431,141 - 65,446,127 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acanthamoeba Keratitis  (ISO)
acne  (ISO)
Acne Conglobata  (ISO)
Acute Coronary Syndrome  (ISO)
acute kidney failure  (IEP,IMP,ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
acute necrotizing pancreatitis  (ISO)
acute pancreatitis  (IEP)
Acute Tubulointerstitial Nephritis  (IMP)
Acute-On-Chronic Liver Failure  (ISO)
age related macular degeneration 10  (ISO)
Alcoholic Fatty Liver  (IMP)
allergic conjunctivitis  (IMP,ISO)
allergic contact dermatitis  (IMP,ISO)
allergic rhinitis  (ISO)
Alzheimer's disease  (ISO)
Angina, Stable  (ISO)
ankylosing spondylitis  (ISO)
anogenital venereal wart  (ISO)
anterior uveitis  (IMP,ISO)
arteriosclerosis  (ISO)
arthritis  (ISO)
asthma  (IDA,IMP,ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
Bacteremia  (ISO)
Bacterial Keratitis  (IMP)
bacterial pneumonia  (IMP)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Bronchial Hyperreactivity  (IMP)
carcinoma  (ISO)
carotid artery disease  (ISO)
carotid stenosis  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Pain  (ISO)
Chronic Periodontitis  (ISO)
colitis  (IMP,ISO)
Colorectal Neoplasms  (ISO)
contact dermatitis  (ISO)
coronary artery disease  (ISO)
Crohn's disease  (ISO)
cutaneous leishmaniasis  (ISO)
cystic echinococcosis  (ISO)
cystic fibrosis  (IMP,ISO)
dermatomyositis  (ISO)
diabetes mellitus  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (IMP)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
dry eye syndrome  (IEP,ISO)
end stage renal disease  (ISO)
Endotoxemia  (IEP,IMP,ISO)
Entamoebiasis  (IMP)
Eosinophilia  (ISO)
esophagus adenocarcinoma  (ISO)
eumycotic mycetoma  (IEP)
exfoliation syndrome  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Autoimmune Uveitis  (IMP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (IEP,ISO)
extrahepatic cholestasis  (ISO)
eye disease  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Fibrosis  (ISO)
Fungal Eye Infections  (ISO)
Fungal Keratitis  (IMP)
glomerulonephritis  (IDA,IMP)
Hearing Loss  (ISO)
Hemorrhagic Shock  (IMP)
hepatocellular carcinoma  (ISO)
hepatorenal syndrome  (ISO)
Herpes Simplex Encephalitis  (ISO)
herpes simplex virus keratitis  (IMP,ISO)
Hyperalgesia  (IMP,ISO)
hypertension  (ISO)
ileitis  (IMP,ISO)
Inflammation  (ISO)
Insulin Resistance  (IAGP,ISO)
invasive aspergillosis  (ISO)
Kawasaki disease  (ISO)
keratitis  (IEP,IMP,ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (IEP,IMP,ISO)
learning disability  (ISO)
leptospirosis  (IMP)
liver cirrhosis  (ISO)
Liver Injury  (IMP)
Liver Reperfusion Injury  (IEP,IMP,ISO)
low tension glaucoma  (ISO)
lung disease  (IEP,IMP,ISO)
Lung Injury  (ISO)
Lung Neoplasms  (ISO)
Lung Reperfusion Injury  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
mastitis  (ISO)
mastoiditis  (ISO)
melanoma  (ISO)
membranoproliferative glomerulonephritis  (IEP)
Meningitis, Escherichia Coli  (IEP)
meningococcal meningitis  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neuralgia  (ISO)
non-alcoholic fatty liver disease  (IMP,ISO)
obesity  (IAGP,ISO)
Onchocerciasis, Ocular  (IMP)
Optic Nerve Injuries  (IEP)
Oral Lichen Planus  (ISO)
otitis media  (IMP,ISO)
Otitis Media with Effusion  (IMP)
Ovarian Neoplasms  (ISO)
Pain  (ISO)
Painful Neuropathy  (IMP)
pancreatitis  (IMP,ISO)
perinatal necrotizing enterocolitis  (ISO)
Plaque, Atherosclerotic  (ISO)
pleural tuberculosis  (ISO)
Pneumococcal Meningitis  (IEP)
pneumonia  (IMP,ISO)
pre-eclampsia  (ISO)
primary open angle glaucoma  (ISO)
Prostatic Neoplasms  (ISO)
Pseudomonas Aeruginosa Keratitis  (IMP,ISO)
psoriasis  (ISO)
pulmonary edema  (IMP)
pulmonary emphysema  (IEA,IMP)
pulmonary fibrosis  (IMP)
pulmonary hypertension  (IMP)
pulmonary tuberculosis  (ISO)
pulpitis  (ISO)
renal fibrosis  (ISO)
Reperfusion Injury  (IMP,ISO)
respiratory allergy  (ISO)
Respiratory Sounds  (ISO)
respiratory syncytial virus infectious disease  (IMP,ISO)
Retina Reperfusion Injury  (IMP)
Rhinosinusitis  (ISO)
sciatic neuropathy  (IEP,ISO)
Seasonal Allergic Rhinitis  (ISO)
Sepsis  (ISO)
sinusitis  (IMP,ISO)
Spinal Cord Injuries  (IMP)
Spinal Cord Reperfusion Injury  (ISO)
sporotrichosis  (IMP)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
suppurative otitis media  (ISO)
systemic lupus erythematosus  (IMP)
temporal arteritis  (ISO)
Transplant Rejection  (IMP)
tuberculosis  (IMP)
tympanosclerosis  (ISO)
type 1 diabetes mellitus  (IEP,ISO)
type 2 diabetes mellitus  (IEP,ISO)
urinary bladder cancer  (IMP)
urinary tract infection  (ISO)
uveitis  (ISO)
Ventricular Dysfunction, Left  (ISO)
Viral Bronchiolitis  (ISO)
viral meningitis  (IEP)
vitiligo  (ISO)
Wallerian Degeneration  (IAGP)
Weight Loss  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-pilocarpine  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(24S)-24-hydroxycholesterol  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,4-dithiothreitol  (EXP)
1,4-phenylenediamine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP)
26-hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
7alpha-hydroxycholesterol  (ISO)
acetamide  (ISO)
acetate ester  (ISO)
acetic acid  (EXP)
acrolein  (ISO)
adenosine  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha-D-galactose  (EXP)
alpha-pinene  (ISO)
aluminium hydroxide  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
artesunate  (ISO)
aspalathin  (ISO)
atorvastatin calcium  (ISO)
auranofin  (EXP)
azathioprine  (EXP)
baicalin  (ISO)
benazepril  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP)
benzylpenicillin  (EXP)
berberine  (EXP)
Besigomsin  (EXP)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol F  (EXP,ISO)
bortezomib  (ISO)
butyric acid  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
casticin  (ISO)
catalpol  (EXP)
cerium trichloride  (EXP)
chaetoglobosin A  (EXP)
chitosan  (ISO)
chlorogenic acid  (EXP,ISO)
chloroquine  (EXP)
chlorothalonil  (ISO)
chlorpyrifos  (ISO)
cholesterol  (ISO)
choline  (EXP)
chromium atom  (ISO)
chrysin  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
cortisol  (ISO)
crocin-1  (ISO)
cudratricusxanthone A  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP)
cyclosporin A  (EXP)
D-glucose  (EXP,ISO)
DAPT  (ISO)
daunorubicin  (EXP)
dehydroepiandrosterone  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
diazinon  (EXP)
dienogest  (ISO)
dihydrogen  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
diprotium  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
enalapril  (ISO)
enalaprilat dihydrate  (ISO)
erythromycin A  (EXP)
esculetin  (EXP)
ethanol  (EXP,ISO)
ethion  (EXP)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
ferulic acid  (EXP)
fisetin  (EXP)
flavonoids  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fructose  (EXP,ISO)
furan  (ISO)
gadolinium trichloride  (ISO)
galactose  (EXP)
gallocatechin  (ISO)
ganglioside GM1  (ISO)
Gastrodin  (ISO)
geldanamycin  (ISO)
genistein  (EXP)
geraniol  (EXP)
Ginkgolide A  (EXP)
ginsenoside Re  (EXP)
glucose  (EXP,ISO)
glutathione  (ISO)
glycyrrhetinate  (EXP)
glycyrrhetinic acid  (EXP)
halothane  (EXP)
helenalin  (EXP)
hexadecanoic acid  (EXP)
hyaluronic acid  (EXP,ISO)
hydroquinone  (EXP)
ifosfamide  (ISO)
indometacin  (EXP,ISO)
irinotecan  (EXP)
iron(2+) sulfate (anhydrous)  (EXP)
isoamylol  (EXP)
isoprenaline  (EXP,ISO)
ivermectin  (ISO)
kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside  (ISO)
ketamine  (EXP)
L-1,4-dithiothreitol  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lactulose  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
linsidomine  (EXP)
lipophosphoglycan  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
liquiritigenin  (ISO)
liquiritin  (ISO)
lithium chloride  (ISO)
LY294002  (EXP)
lycopene  (ISO)
magnesium dihydroxide  (EXP)
malathion  (EXP)
melatonin  (ISO)
melittin  (EXP)
melphalan  (ISO)
metformin  (ISO)
methadone  (ISO)
methamphetamine  (EXP,ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
Methylthiouracil  (ISO)
monocrotaline  (EXP,ISO)
monodansylcadaverine  (EXP)
morphine  (EXP,ISO)
Morphine-3-glucuronide  (ISO)
muramyl dipeptide  (EXP,ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
naloxone  (ISO)
naproxen  (ISO)
nerolidol  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicorandil  (ISO)
nicotine  (ISO)
nitric oxide  (EXP)
Nonidet P-40  (ISO)
Nonylphenol  (EXP,ISO)
o-anisidine  (ISO)
omeprazole  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PD 0325901  (ISO)
pelargonidin  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidylinositol dimannoside  (EXP)
phosphoramide mustard  (ISO)
picropodophyllotoxin  (EXP)
pipoxolan  (EXP)
pirinixic acid  (EXP)
platycodin D  (ISO)
polymyxin B2  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
probenecid  (EXP)
progesterone  (ISO)
propofol  (EXP)
puerarin  (EXP)
Pyridostigmine bromide  (EXP)
quercetin  (EXP,ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
rosmarinic acid  (ISO)
S-allylcysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
Salvianolic acid A  (EXP)
salvianolic acid B  (ISO)
SB 431542  (ISO)
Scoparone  (EXP)
scopoletin  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium cholate  (ISO)
streptozocin  (EXP,ISO)
succimer  (EXP)
sulfasalazine  (EXP)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
sumatriptan  (ISO)
telmisartan  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetrachloropalladate(2-)  (ISO)
thioacetamide  (ISO)
thymoquinone  (ISO)
titanium atom  (EXP,ISO)
titanium dioxide  (EXP)
toluene  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin D  (EXP,ISO)
zinc atom  (ISO)
zinc oxide  (EXP)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)
zingerone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (IMP)
activation of NF-kappaB-inducing kinase activity  (NAS)
astrocyte development  (IMP)
B cell proliferation involved in immune response  (IMP)
cellular response to amyloid-beta  (ISO)
cellular response to interferon-gamma  (ISO)
cellular response to lipopolysaccharide  (IDA,IMP,ISO,TAS)
cellular response to lipoteichoic acid  (IMP)
cellular response to mechanical stimulus  (ISO)
cellular response to oxidised low-density lipoprotein particle stimulus  (IGI)
cellular response to platelet-derived growth factor stimulus  (IMP)
cellular response to retinoic acid  (ISO)
defense response to bacterium  (ISO)
defense response to Gram-negative bacterium  (IBA,IMP)
detection of lipopolysaccharide  (IDA,ISO,TAS)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
I-kappaB phosphorylation  (IMP,ISO)
immune response  (IEA)
immune system process  (IEA)
immunoglobulin mediated immune response  (ISO)
inflammatory response  (IBA,IMP,ISO)
innate immune response  (TAS)
innate immune response-activating signal transduction  (ISO)
intestinal epithelial structure maintenance  (IMP)
leukotriene metabolic process  (ISO)
lipopolysaccharide-mediated signaling pathway  (IDA,IGI,ISO)
macrophage activation  (ISO,ISS,TAS)
mast cell activation  (NAS)
microglial cell activation  (ISO)
MyD88-dependent toll-like receptor signaling pathway  (IGI)
negative regulation of cold-induced thermogenesis  (IMP)
negative regulation of ERK1 and ERK2 cascade  (IMP)
negative regulation of interferon-gamma production  (IMP)
negative regulation of interleukin-17 production  (IMP)
negative regulation of interleukin-23 production  (IMP)
negative regulation of interleukin-6 production  (IMP)
negative regulation of tumor necrosis factor production  (IMP)
nitric oxide production involved in inflammatory response  (IMP)
phagocytosis  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of B cell proliferation  (IMP)
positive regulation of cellular response to macrophage colony-stimulating factor stimulus  (ISO)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of chemokine production  (IDA,ISO)
positive regulation of cytokine production involved in inflammatory response  (IGI,ISO)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of gene expression  (IGI,IMP,ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IDA)
positive regulation of inflammatory response  (IGI,ISO)
positive regulation of interferon-alpha production  (IDA)
positive regulation of interferon-beta production  (IDA,IMP)
positive regulation of interferon-gamma production  (IMP)
positive regulation of interleukin-1 beta production  (IDA,ISO)
positive regulation of interleukin-1 production  (IDA,NAS)
positive regulation of interleukin-10 production  (IDA)
positive regulation of interleukin-12 production  (IDA,ISO)
positive regulation of interleukin-13 production  (NAS)
positive regulation of interleukin-6 production  (IDA,IMP,ISO,NAS)
positive regulation of interleukin-8 production  (ISO)
positive regulation of JNK cascade  (IDA,IGI)
positive regulation of lymphocyte proliferation  (IMP)
positive regulation of macrophage activation  (IGI)
positive regulation of macrophage cytokine production  (IMP)
positive regulation of MAP kinase activity  (IMP)
positive regulation of matrix metallopeptidase secretion  (ISO)
positive regulation of MHC class II biosynthetic process  (IMP)
positive regulation of NF-kappaB transcription factor activity  (IMP,ISO)
positive regulation of NIK/NF-kappaB signaling  (ISO)
positive regulation of nitric oxide biosynthetic process  (IGI,IMP)
positive regulation of nitric-oxide synthase biosynthetic process  (IDA)
positive regulation of NLRP3 inflammasome complex assembly  (IDA)
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway  (IDA)
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway  (IDA)
positive regulation of oxidative stress-induced neuron death  (IGI)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of platelet activation  (IMP)
positive regulation of reactive oxygen species biosynthetic process  (IMP)
positive regulation of smooth muscle cell migration  (IMP)
positive regulation of smooth muscle cell proliferation  (IMP)
positive regulation of stress-activated MAPK cascade  (IDA)
positive regulation of transcription by RNA polymerase II  (IDA)
positive regulation of tumor necrosis factor production  (IDA,IMP,ISO)
regulation of dendritic cell cytokine production  (IDA)
regulation of inflammatory response  (IMP)
regulation of sensory perception of pain  (ISO)
regulation of tumor necrosis factor production  (ISO)
response to activity  (ISO)
response to bacterium  (IMP)
response to ethanol  (ISO)
response to fatty acid  (ISO)
response to glucocorticoid  (ISO)
response to gold nanoparticle  (ISO)
response to hypoxia  (ISO)
response to insulin  (ISO)
response to lipopolysaccharide  (IGI,IMP,ISO)
response to morphine  (ISO)
response to oxidative stress  (ISO)
response to progesterone  (ISO)
response to retinoic acid  (ISO)
response to toxic substance  (ISO)
signal transduction  (IEA)
skeletal muscle contraction  (ISO)
toll-like receptor 4 signaling pathway  (IDA)
toll-like receptor signaling pathway  (IBA,ISO)
TRIF-dependent toll-like receptor signaling pathway  (IGI)
wound healing involved in inflammatory response  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acute inflammation  (IAGP)
abnormal airway responsiveness  (IAGP)
abnormal artery morphology  (IAGP)
abnormal bile salt level  (IAGP)
abnormal bone structure  (IAGP)
abnormal cecum morphology  (IEA)
abnormal chemokine secretion  (IAGP)
abnormal circulating enzyme level  (IAGP)
abnormal circulating glucose level  (IAGP)
abnormal circulating leptin level  (IAGP)
abnormal colon morphology  (IAGP)
abnormal cytokine level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal enterocyte differentiation  (IAGP)
abnormal enterocyte proliferation  (IAGP)
abnormal fatty acids level  (IAGP)
abnormal fibroblast proliferation  (IAGP)
abnormal gas homeostasis  (IAGP)
abnormal glial cell apoptosis  (IAGP)
abnormal glial cell physiology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal granulocyte physiology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal immune cell physiology  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal interleukin level  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal level of surface class II molecules  (IAGP)
abnormal lipid level  (IAGP)
abnormal liver physiology  (IAGP)
abnormal locomotor behavior  (IAGP)
abnormal lung interstitium morphology  (IAGP)
abnormal macrophage chemotaxis  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal microglial cell physiology  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal muscle cell glucose uptake  (IAGP)
abnormal myelin sheath morphology  (IAGP)
abnormal nephron morphology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal NK cell physiology  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal phagocyte morphology  (IAGP)
abnormal proximal convoluted tubule brush border morphology  (IAGP)
abnormal pulmonary alveolar duct morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal pulmonary elastic fiber morphology  (IAGP)
abnormal renal tubule epithelium morphology  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal respiratory system morphology  (IAGP)
abnormal respiratory system physiology  (IAGP)
abnormal retinal layer morphology  (IAGP)
abnormal retinal pigment epithelium morphology  (IAGP)
abnormal retinal progenitor cell morphology  (IAGP)
abnormal retinal rod bipolar cell morphology  (IAGP)
abnormal retinal rod cell morphology  (IAGP)
abnormal spleen weight  (IAGP)
abnormal susceptibility to atherosclerosis  (IAGP)
abnormal susceptibility to infection  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
abnormal uterus morphology  (IEA)
abnormal vascular wound healing  (IAGP)
atherosclerotic lesions  (IAGP)
brain ischemia  (IAGP)
cellular necrosis  (IEA)
colitis  (IAGP)
decreased acute inflammation  (IAGP)
decreased angiogenesis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased body size  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased cerebral infarct size  (IAGP)
decreased circulating alanine transaminase level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating interleukin-6 level  (IAGP)
decreased colon length  (IAGP)
decreased epididymal fat pad weight  (IAGP)
decreased eye pigmentation  (IEA)
decreased fat cell size  (IAGP)
decreased heart weight  (IEA)
decreased hemoglobin content  (IAGP)
decreased hepatocyte apoptosis  (IAGP)
decreased IgG3 level  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased interferon-beta secretion  (IEA)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-1 beta secretion  (IEA)
decreased interleukin-10 secretion  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased macrophage apoptosis  (IEA)
decreased macrophage cytokine production  (IEA)
decreased memory B cell number  (IEA)
decreased neuron apoptosis  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased respiratory quotient  (IAGP)
decreased response of heart to induced stress  (IAGP)
decreased sensitivity to induced morbidity/mortality  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to bone fracture  (IAGP)
decreased susceptibility to endotoxin shock  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased susceptibility to injury  (IAGP)
decreased susceptibility to ischemic brain injury  (IAGP)
decreased susceptibility to kidney reperfusion injury  (IAGP)
decreased susceptibility to Orthomyxoviridae infection  (IAGP)
decreased susceptibility to weight loss  (IAGP)
decreased tail pigmentation  (IEA)
decreased tumor necrosis factor secretion  (IAGP)
dilated pulmonary alveolar ducts  (IAGP)
dilated renal tubules  (IAGP)
diluted coat color  (IEA)
enlarged cecum  (IEA)
enlarged lung  (IAGP)
enlarged mesenteric lymph nodes  (IAGP)
enlarged uterus  (IEA)
focal hepatic necrosis  (IAGP)
hyperoxia  (IAGP)
hyporesponsive to tactile stimuli  (IAGP)
impaired neutrophil chemotaxis  (IAGP)
improved glucose tolerance  (IAGP)
increased adiponectin level  (IAGP)
increased apoptosis  (IAGP)
increased B-1 B cell number  (IAGP)
increased bone mass  (IAGP)
increased bone mineral content  (IAGP)
increased bone mineral density  (IAGP)
increased cell death  (IEA)
increased circulating interleukin-6 level  (IAGP)
increased interleukin-4 secretion  (IAGP)
increased lung compliance  (IAGP)
increased oxygen consumption  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to induced arthritis  (IAGP)
increased susceptibility to Poxviridae infection induced morbidity/mortality  (IAGP)
increased thermal nociceptive threshold  (IAGP)
increased total body fat amount  (IEA)
large intestinal inflammation  (IAGP)
liver inflammation  (IAGP)
lung inflammation  (IAGP)
no abnormal phenotype detected  (IEA)
polyphagia  (IAGP)
pulmonary edema  (IAGP)
rectal hemorrhage  (IAGP)
renal cast  (IAGP)
renal tubular necrosis  (IAGP)
References

References - curated
1. Abel B, etal., J Immunol. 2002 Sep 15;169(6):3155-62.
2. Akbal E, etal., Viral Immunol. 2017 May;30(4):278-282. doi: 10.1089/vim.2016.0131. Epub 2017 Apr 17.
3. Algandaby MM, etal., Naunyn Schmiedebergs Arch Pharmacol. 2016 Apr;389(4):419-28. doi: 10.1007/s00210-016-1210-1. Epub 2016 Jan 26.
4. Ali I, etal., Ann Thorac Surg. 2012 Jan;93(1):282-8. doi: 10.1016/j.athoracsur.2011.08.074. Epub 2011 Nov 23.
5. Alpay HC, etal., Auris Nasus Larynx. 2010 Feb;37(1):29-32. doi: 10.1016/j.anl.2009.03.001. Epub 2009 Apr 26.
6. Alvarez-Rodriguez L, etal., Rheumatology (Oxford). 2011 Sep;50(9):1562-8. doi: 10.1093/rheumatology/ker168. Epub 2011 May 17.
7. Andersson A, etal., J Leukoc Biol. 2008 Nov;84(5):1248-55. Epub 2008 Jul 21.
8. Assassi S, etal., J Rheumatol. 2011 Jan;38(1):87-98. doi: 10.3899/jrheum.100469. Epub 2010 Oct 15.
9. Aumeunier A, etal., PLoS One. 2010 Jul 7;5(7):e11484.
10. Awomoyi AA, etal., J Immunol. 2007 Sep 1;179(5):3171-7.
11. Bagarolli RA, etal., J Diabetes Complications. 2009 Apr 21.
12. Banas MC, etal., J Am Soc Nephrol. 2008 Apr;19(4):704-13. doi: 10.1681/ASN.2007040395. Epub 2008 Feb 6.
13. Ben Dhifallah I, etal., Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S58-62.
14. Ben-Ari Z, etal., Cell Physiol Biochem. 2012;30(2):489-98. doi: 10.1159/000341432. Epub 2012 Jul 13.
15. Bereczky-Veress B, etal., PLoS One. 2010 Aug 27;5(8):e12350.
16. Bettoni I, etal., Glia. 2008 Sep;56(12):1312-9. doi: 10.1002/glia.20699.
17. Boivin A, etal., J Neurosci. 2007 Nov 14;27(46):12565-76.
18. Bonini S, etal., Ophthalmology. 2005 Sep;112(9):1528; discussion 1548-9.
19. Bottcher T, etal., Neurosci Lett. 2003 Jun 19;344(1):17-20.
20. Braga TT, etal., Mol Med. 2012 Oct 24;18:1231-9. doi: 10.2119/molmed.2012.00131.
21. Brown HJ, etal., J Immunol. 2006 Aug 1;177(3):1925-31.
22. Buraczynska M, etal., Hum Immunol. 2009 Feb;70(2):121-4. Epub 2009 Jan 7.
23. Canale-Zambrano JC, etal., Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G381-90. Epub 2010 Jun 3.
24. Carvalho A, etal., J Infect Dis. 2008 Feb 15;197(4):618-21.
25. Casale TB, etal., Ann Allergy Asthma Immunol. 2006 Oct;97(4):454-6.
26. Castoldi A, etal., PLoS One. 2012;7(5):e37584. doi: 10.1371/journal.pone.0037584. Epub 2012 May 24.
27. Chang JH, etal., Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1711-7.
28. Chassin C, etal., J Immunol. 2009 Aug 15;183(4):2669-77. doi: 10.4049/jimmunol.0900506. Epub 2009 Jul 27.
29. Chen C, etal., Shock. 2009 May;31(5):486-92.
30. Chen G, etal., Ann Clin Lab Sci. 2008 Winter;38(1):65-74.
31. Chen W, etal., Mol Vis. 2009;15:619-28. Epub 2009 Mar 30.
32. Chen X, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2014 Nov;34(11):1584-8.
33. Cho HJ, etal., Ann Allergy Asthma Immunol. 2011 Jul;107(1):57-64. doi: 10.1016/j.anai.2011.04.003. Epub 2011 May 19.
34. Cho Y, etal., Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5614-8. doi: 10.1167/iovs.09-3688. Epub 2009 Jul 23.
35. Chung SH, etal., Clin Exp Immunol. 2011 May;164(2):275-81. doi: 10.1111/j.1365-2249.2011.04368.x. Epub 2011 Mar 10.
36. Correa-Costa M, etal., PLoS One. 2011;6(12):e29004. doi: 10.1371/journal.pone.0029004. Epub 2011 Dec 14.
37. Cundy T, etal., Hum Mol Genet. 2002 Sep 1;11(18):2119-27.
38. Deng YN and Zhou WB, Neuroimmunomodulation. 2007;14(6):337-43. Epub 2008 Apr 23.
39. Deng ZB, etal., Diabetes. 2009 Aug 12.
40. Despriet DD, etal., Invest Ophthalmol Vis Sci. 2008 Jan;49(1):364-71. doi: 10.1167/iovs.07-0656.
41. Devaraj S, etal., J Clin Endocrinol Metab. 2008 Feb;93(2):578-83. Epub 2007 Nov 20.
42. Ding N, etal., Circ Cardiovasc Genet. 2014 Oct;7(5):615-24. doi: 10.1161/CIRCGENETICS.113.000398. Epub 2014 Jul 21.
43. Du T, etal., Clin Chim Acta. 2009 Apr;402(1-2):133-8. Epub 2009 Jan 11.
44. Du T, etal., Diabetes Res Clin Pract. 2009 Feb;83(2):208-14. Epub 2008 Nov 17.
45. Dvoriantchikova G, etal., Mol Vis. 2010 Sep 30;16:1907-12.
46. Ehsan N, etal., Tumour Biol. 2013 Apr;34(2):1053-9. doi: 10.1007/s13277-013-0645-y. Epub 2013 Jan 22.
47. Ekman AK, etal., Int Arch Allergy Immunol. 2012;159(1):6-14. doi: 10.1159/000335196. Epub 2012 Apr 27.
48. Enquobahrie DA, etal., Am J Cardiol. 2008 Jun 15;101(12):1683-8. Epub 2008 Apr 9.
49. Etokebe GE, etal., Genet Test Mol Biomarkers. 2009 Dec;13(6):729-34. doi: 10.1089/gtmb.2009.0045.
50. Fageras Bottcher M, etal., J Allergy Clin Immunol. 2004 Sep;114(3):561-7.
51. Forte A, etal., Cardiovasc Drugs Ther. 2012 Feb;26(1):9-21. doi: 10.1007/s10557-011-6359-8.
52. Fransson M, etal., Respir Res. 2005 Sep 7;6:100.
53. Froy O, etal., Mol Immunol. 2007 Feb;44(5):796-802. Epub 2006 Jun 5.
54. Fuertes E, etal., J Allergy Clin Immunol. 2013 Aug;132(2):342-52.e2. doi: 10.1016/j.jaci.2013.03.007. Epub 2013 Apr 30.
55. Gagro A, etal., Clin Exp Immunol. 2004 Feb;135(2):267-72.
56. Gao Q, etal., Am J Transplant. 2010 Jul;10(7):1588-96. doi: 10.1111/j.1600-6143.2010.03151.x.
57. Gao Y and Guo ZP, Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Jul;40(4):655-7.
58. Garantziotis S, etal., Am J Respir Crit Care Med. 2010 Apr 1;181(7):666-75. Epub 2009 Dec 10.
59. Garcia-Rodriguez S, etal., J Eur Acad Dermatol Venereol. 2013 Feb;27(2):242-50.
60. Genuneit J, etal., Clin Exp Allergy. 2009 Dec;39(12):1875-88.
61. Grech I, etal., J Eur Acad Dermatol Venereol. 2012 Dec;26(12):1538-43. doi: 10.1111/j.1468-3083.2011.04338.x. Epub 2011 Nov 16.
62. Guo LH, etal., Biochem Biophys Res Commun. 2006 Oct 27;349(3):1156-62. Epub 2006 Sep 1.
63. Halfhide CP, etal., Thorax. 2009 Sep;64(9):798-805. Epub 2009 Jun 3.
64. Hammad H, etal., Nat Med. 2009 Apr;15(4):410-6. Epub 2009 Mar 29.
65. Hawn TR, etal., PLoS One. 2009 Jun 22;4(6):e5990. doi: 10.1371/journal.pone.0005990.
66. He D, etal., Int Immunopharmacol. 2016 Jun;35:201-209. doi: 10.1016/j.intimp.2016.03.032. Epub 2016 Apr 16.
67. He Z, etal., Respir Res. 2009 Dec 18;10:126.
68. Heimesaat MM, etal., Gut. 2007 Jul;56(7):941-8. Epub 2007 Jan 25.
69. Hirai H, etal., Int J Pediatr Otorhinolaryngol. 2013 May;77(5):674-6. doi: 10.1016/j.ijporl.2013.01.010. Epub 2013 Feb 4.
70. Hochhauser E, etal., PLoS One. 2013 Aug 15;8(8):e73041. doi: 10.1371/journal.pone.0073041. eCollection 2013.
71. Holloway JW, etal., Pharmacogenet Genomics. 2005 Jan;15(1):15-21.
72. Horie Y, etal., Rheumatology (Oxford). 2009 Jun;48(6):638-42. doi: 10.1093/rheumatology/kep077. Epub 2009 Apr 24.
73. Hsieh YY, etal., Int J Biol Sci. 2009;5(1):74-81. Epub 2009 Jan 9.
74. Hu J, etal., Invest Ophthalmol Vis Sci. 2009 May;50(5):2087-94. doi: 10.1167/iovs.07-1237. Epub 2008 Dec 13.
75. Hua J, etal., J Gastroenterol Hepatol. 2007 Jun;22(6):862-9. doi: 10.1111/j.1440-1746.2007.04896.x. Epub 2007 May 17.
76. Huang D, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2009 Nov;21(11):644-7.
77. Huang X, etal., Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4910-6.
78. Hussein YM, etal., Cell Immunol. 2012;274(1-2):34-8. doi: 10.1016/j.cellimm.2012.02.006. Epub 2012 Feb 17.
79. Hutchinson MR, etal., Eur J Neurosci. 2008 Jul;28(1):20-9.
80. Illig T, etal., Diabetes. 2003 Nov;52(11):2861-4.
81. Impellizzeri D, etal., Immunobiology. 2015 Sep;220(9):1039-49. doi: 10.1016/j.imbio.2015.05.013. Epub 2015 May 11.
82. Inokuchi S, etal., Alcohol Clin Exp Res. 2011 Aug;35(8):1509-18. doi: 10.1111/j.1530-0277.2011.01487.x. Epub 2011 Apr 4.
83. Jesic S, etal., Ann Otol Rhinol Laryngol. 2014 Apr 1.
84. Jeyaseelan S, etal., Infect Immun. 2005 Mar;73(3):1754-63.
85. Jia L, etal., Mol Metab. 2018 Aug;14:121-129. doi: 10.1016/j.molmet.2018.05.015. Epub 2018 May 23.
86. Jiang W, etal., Transplant Proc. 2011 Jun;43(5):1462-7.
87. Jiang ZC, etal., Tumour Biol. 2014 Dec;35(12):12345-52. doi: 10.1007/s13277-014-2547-z. Epub 2014 Sep 2.
88. Jie Zhao, etal., Innate Immun. 2009 Jun;15(3):155-68.
89. Jin X, etal., Cornea. 2007 Aug;26(7):847-52.
90. Jin X, etal., Curr Eye Res. 2008 Apr;33(4):319-24. doi: 10.1080/02713680802008238.
91. Jin X, etal., Eur J Clin Microbiol Infect Dis. 2010 Feb;29(2):231-8. doi: 10.1007/s10096-009-0844-z. Epub 2009 Dec 13.
92. Jing K and Sun M, Zhongguo Dang Dai Er Ke Za Zhi. 2011 Dec;13(12):985-8.
93. Kang I, etal., Eur Arch Otorhinolaryngol. 2010 Mar;267(3):385-9. Epub 2009 Sep 18.
94. Karaca N, etal., J Eur Acad Dermatol Venereol. 2013 Jan;27(1):e85-90. doi: 10.1111/j.1468-3083.2012.04514.x. Epub 2012 Mar 16.
95. Katsargyris A, etal., Expert Opin Ther Targets. 2010 Jan;14(1):1-10. doi: 10.1517/14728220903401294.
96. Kerkhof M, etal., Thorax. 2010 Aug;65(8):690-7.
97. Kim GT, etal., Clin Rheumatol. 2010 Mar;29(3):273-9. doi: 10.1007/s10067-009-1316-7. Epub 2009 Dec 2.
98. Kim K, etal., Clin Nutr. 2013 Oct;32(5):855-62. doi: 10.1016/j.clnu.2012.11.026. Epub 2013 Jan 23.
99. Kim YM, etal., Am J Obstet Gynecol. 2005 Sep;193(3 Pt 2):921-7.
100. Kirino Y, etal., Arthritis Res Ther. 2008;10(1):R16. doi: 10.1186/ar2367. Epub 2008 Jan 31.
101. Kitazawa T, etal., J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e494-8. Epub 2007 Dec 7.
102. Kitazawa T, etal., J Gastroenterol Hepatol. 2010 May;25(5):1009-12. doi: 10.1111/j.1440-1746.2009.06145.x.
103. Knapp S, etal., Am J Respir Crit Care Med. 2006 Jan 1;173(1):122-9. Epub 2005 Oct 6.
104. Koc M, etal., Nephrol Dial Transplant. 2011 Mar;26(3):955-63. doi: 10.1093/ndt/gfq500. Epub 2010 Aug 20.
105. Kolek MJ, etal., Am Heart J. 2004 Dec;148(6):1034-40.
106. Koreck A, etal., Dermatology. 2006;213(3):267-9.
107. Kuang X, etal., Eur J Pharmacol. 2012 Feb 15;676(1-3):51-6. doi: 10.1016/j.ejphar.2011.11.037. Epub 2011 Dec 7.
108. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
109. Kwok YH, etal., PLoS One. 2013 Oct 30;8(10):e77799. doi: 10.1371/journal.pone.0077799. eCollection 2013.
110. Lartigue A, etal., J Immunol. 2009 Nov 15;183(10):6207-16. doi: 10.4049/jimmunol.0803219. Epub 2009 Oct 19.
111. Lauriello M, etal., Int J Otolaryngol. 2012;2012:925164. doi: 10.1155/2012/925164. Epub 2012 Apr 10.
112. Leal SM Jr, etal., PLoS Pathog. 2010 Jul 1;6:e1000976. doi: 10.1371/journal.ppat.1000976.
113. Leichtle A, etal., Innate Immun. 2009 Aug;15(4):205-15. doi: 10.1177/1753425909103170. Epub 2009 Jul 8.
114. Levchenko LIu, etal., Tsitol Genet. 2013 May-Jun;47(3):46-53.
115. Li C, etal., Cardiovasc Res 2004 Feb 15;61(3):538-47.
116. Li DQ, etal., J Allergy Clin Immunol. 2011 Dec;128(6):1318-1325.e2. doi: 10.1016/j.jaci.2011.06.041. Epub 2011 Aug 6.
117. Li H, etal., Anesthesiology. 2010 Sep;113(3):619-29.
118. Li SL, etal., Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Dec;46(12):1009-18.
119. Li X, etal., Inflamm Res. 2013 Jul;62(7):703-9. doi: 10.1007/s00011-013-0624-1. Epub 2013 Apr 17.
120. Li X, etal., Toxicol Lett. 2016 Nov 2;261:1-12. doi: 10.1016/j.toxlet.2016.09.002. Epub 2016 Sep 4.
121. Li XQ, etal., PLoS One. 2016 Oct 19;11(10):e0163807. doi: 10.1371/journal.pone.0163807. eCollection 2016.
122. Lim SW, etal., Transplantation. 2005 Sep 15;80(5):691-9.
123. Lin M, etal., J Am Soc Nephrol. 2012 Jan;23(1):86-102. doi: 10.1681/ASN.2010111210. Epub 2011 Oct 21.
124. Liu A, etal., Histochem Cell Biol. 2011 May;135(5):443-52. doi: 10.1007/s00418-011-0802-6. Epub 2011 Mar 24.
125. Liu L, etal., Clin Res Hepatol Gastroenterol. 2016 Nov;40(5):575-583. doi: 10.1016/j.clinre.2016.02.008. Epub 2016 Apr 6.
126. Liu Y, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G442-50. Epub 2009 Jul 16.
127. Lu ZQ, etal., Zhonghua Yi Xue Za Zhi. 2009 Jan 13;89(2):138-41.
128. Lubbad A, etal., Mol Cell Biochem. 2009 Feb;322(1-2):127-35. Epub 2008 Nov 11.
129. Lun SW, etal., J Clin Immunol. 2009 May;29(3):330-42. Epub 2008 Dec 6.
130. Luxameechanporn T, etal., Arch Otolaryngol Head Neck Surg. 2005 Nov;131(11):1001-6.
131. Ma CX, etal., Chin Med J (Engl). 2009 Jul 5;122(13):1575-81.
132. Maldonado-Bernal C, etal., Parasite Immunol. 2005 Apr;27(4):127-37.
133. Mano SS, etal., Int J Mol Sci. 2013 Jun 26;14(7):13154-70. doi: 10.3390/ijms140713154.
134. Martin SF, etal., J Exp Med. 2008 Sep 1;205(9):2151-62. doi: 10.1084/jem.20070509. Epub 2008 Aug 25.
135. Meguro A, etal., Ann Rheum Dis. 2008 May;67(5):725-7. doi: 10.1136/ard.2007.079871.
136. Methe H, etal., Circulation. 2005 May 24;111(20):2654-61. Epub 2005 May 9.
137. MGD and Homologene mouse data transfer
138. MGD data from the GO Consortium
139. MGD IEA
140. Milanski M, etal., J Neurosci. 2009 Jan 14;29(2):359-70.
141. Millan-Chiu BE, etal., FEMS Immunol Med Microbiol. 2011 Apr;61(3):278-87. doi: 10.1111/j.1574-695X.2010.00775.x. Epub 2011 Jan 31.
142. Minmin S, etal., PLoS One. 2011 Apr 29;6(4):e19466. doi: 10.1371/journal.pone.0019466.
143. Minoretti P, etal., Neurosci Lett. 2006 Jan 2;391(3):147-9. Epub 2005 Sep 12.
144. Mohammad MK, etal., Int Immunol. 2006 Jul;18(7):1101-13. Epub 2006 May 25.
145. Murawski MR, etal., J Virol. 2009 Feb;83(3):1492-500. Epub 2008 Nov 19.
146. Najmi N, etal., Tissue Antigens. 2010 Aug;76(2):102-9. Epub 2010 Apr 8.
147. Nara K, etal., Clin Exp Immunol. 2008 May;152(2):245-51. doi: 10.1111/j.1365-2249.2008.03626.x. Epub 2008 Mar 10.
148. Ohara K, etal., J Neuroinflammation. 2013 Nov 23;10:139. doi: 10.1186/1742-2094-10-139.
149. OMIM Disease Annotation Pipeline
150. Palomino-Morales R, etal., J Rheumatol. 2009 Jul;36(7):1501-6. doi: 10.3899/jrheum.081286. Epub 2009 Jun 16.
151. Pan MM, etal., Zhonghua Yi Xue Za Zhi. 2008 Aug 5;88(30):2103-7.
152. Park SH, etal., Pharmacol Ther. 2012 Mar;133(3):291-8. doi: 10.1016/j.pharmthera.2011.11.001. Epub 2011 Nov 19.
153. Pasternak BA, etal., Inflamm Bowel Dis. 2010 May;16(5):856-69. doi: 10.1002/ibd.21132.
154. Paulus SC, etal., Clin Immunol. 2007 Jun;123(3):252-7. Epub 2007 Apr 20.
155. Paun A, etal., Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1198-205.
156. Peng Y, etal., Surgery. 2008 May;143(5):679-85. doi: 10.1016/j.surg.2008.01.005.
157. Pipeline to import KEGG annotations from KEGG into RGD
158. Poggi M, etal., Diabetologia. 2007 Apr 11;.
159. Prabha C, etal., Immunol Lett. 2008 Apr 15;117(1):26-34. Epub 2007 Dec 3.
160. Puthothu B, etal., Dis Markers. 2006;22(5-6):303-8.
161. Redfern RL, etal., Invest Ophthalmol Vis Sci. 2013 Feb 28;54(2):1554-63. doi: 10.1167/iovs.12-10739.
162. Reismann P, etal., J Neurol. 2004 Jul;251(7):853-8.
163. Ren MY and Wu XY, Parasite Immunol. 2011 Jan;33(1):25-33. doi: 10.1111/j.1365-3024.2010.01247.x.
164. Reyna SM, etal., Diabetes. 2008 Oct;57(10):2595-602. Epub 2008 Jul 15.
165. RGD automated import pipeline
166. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
167. RGD automated import pipeline for gene-chemical interactions
168. Rojo-Botello NR, etal., J Periodontal Res. 2012 Feb;47(1):62-73. doi: 10.1111/j.1600-0765.2011.01405.x. Epub 2011 Aug 17.
169. Rosas-Taraco AG, etal., J Infect Dis. 2007 Dec 1;196(11):1698-706. Epub 2007 Oct 25.
170. Rudofsky G Jr, etal., Diabetes Care. 2004 Jan;27(1):179-83.
171. Rusai K, etal., Pediatr Nephrol. 2010 May;25(5):853-60. doi: 10.1007/s00467-009-1422-4. Epub 2010 Feb 4.
172. Sackesen C, etal., Allergy. 2005 Dec;60(12):1485-92.
173. Sadik NA, etal., Arch Virol. 2015 Sep;160(9):2181-95. doi: 10.1007/s00705-015-2493-0. Epub 2015 Jun 23.
174. Saint Andre Av, etal., Science. 2002 Mar 8;295(5561):1892-5.
175. Sarangi PP, etal., J Virol. 2007 Oct;81(20):11128-38. Epub 2007 Aug 8.
176. Saraswathy S, etal., Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3680-6. doi: 10.1167/iovs.09-4575. Epub 2010 Mar 5.
177. Sassa MF, etal., Immunology. 2009 Oct;128(2):301-9. doi: 10.1111/j.1365-2567.2009.03118.x.
178. Sawa H, etal., Hepatogastroenterology. 2008 Nov-Dec;55(88):2247-51.
179. Schmidt M, etal., Nat Immunol. 2010 Sep;11(9):814-9. doi: 10.1038/ni.1919. Epub 2010 Aug 15.
180. Senthilselvan A, etal., Ann Allergy Asthma Immunol. 2008 May;100(5):463-8.
181. Shah N, etal., J Hepatol. 2012 May;56(5):1047-53. Epub 2012 Jan 17.
182. Shan JY, etal., Parasite Immunol. 2011 Dec;33(12):692-6. doi: 10.1111/j.1365-3024.2011.01335.x.
183. Sharif R, etal., Gut. 2009 Jun;58(6):813-9. Epub 2009 Feb 6.
184. Shi H, etal., J Clin Invest. 2006 Nov;116(11):3015-25. Epub 2006 Oct 19.
185. Shi YJ, etal., Mol Med Rep. 2013 Aug;8(2):480-6. doi: 10.3892/mmr.2013.1511. Epub 2013 Jun 6.
186. Shimamoto A, etal., Ann Thorac Surg. 2006 Dec;82(6):2017-23.
187. Shirai Y, etal., J Gastroenterol Hepatol. 2013 Apr;28(4):723-30. doi: 10.1111/jgh.12112.
188. Si Y, etal., Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 May;47(5):388-93.
189. Silva MA, etal., Inflamm Bowel Dis. 2008 May;14(5):632-44.
190. Singh K, etal., Biomed Res Int. 2013;2013:318686. doi: 10.1155/2013/318686. Epub 2013 Jul 11.
191. Siponen M, etal., J Oral Pathol Med. 2012 Nov;41(10):741-7. doi: 10.1111/j.1600-0714.2012.01169.x. Epub 2012 Jun 5.
192. Speletas M, etal., Clin Dev Immunol. 2009;2009:260286. Epub 2010 Feb 15.
193. Speletas M, etal., Hum Immunol. 2009 Sep;70(9):750-3. doi: 10.1016/j.humimm.2009.05.004. Epub 2009 May 13.
194. Sturges NC, etal., Pediatr Pulmonol. 2010 Sep;45(9):883-9.
195. Suh W, etal., Mol Vis. 2011;17:2343-8. Epub 2011 Aug 31.
196. Summers SA, etal., Kidney Int. 2010 Sep 15.
197. Sun Y, etal., Am J Rhinol Allergy. 2012 Mar-Apr;26(2):104-9. doi: 10.2500/ajra.2012.26.3718. Epub 2011 Dec 16.
198. Sun Y, etal., Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1511-6. doi: 10.1167/iovs.09-4237. Epub 2009 Oct 29.
199. Takano Y, etal., Am J Ophthalmol. 2012 Nov;154(5):825-832.e1. doi: 10.1016/j.ajo.2012.03.050. Epub 2012 Jul 24.
200. Takeuchi A, etal., Int Immunopharmacol. 2009 Dec;9(13-14):1562-7. doi: 10.1016/j.intimp.2009.09.012. Epub 2009 Sep 27.
201. Tanga FY, etal., Neurochem Int 2004 Jul-Aug;45(2-3):397-407.
202. Tanga FY, etal., Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5856-61. Epub 2005 Apr 4.
203. Testro AG, etal., J Hepatol. 2010 Feb;52(2):199-205. doi: 10.1016/j.jhep.2009.11.006. Epub 2009 Dec 16.
204. Theodoropoulos GE, etal., Breast. 2012 Aug;21(4):534-8. doi: 10.1016/j.breast.2012.04.001. Epub 2012 May 2.
205. Tittarelli A, etal., Cancer Immunol Immunother. 2012 Nov;61(11):2067-77. doi: 10.1007/s00262-012-1268-7. Epub 2012 May 3.
206. Tu CT, etal., Food Chem Toxicol. 2012 Sep;50(9):3343-51. doi: 10.1016/j.fct.2012.05.050. Epub 2012 Jun 7.
207. Tullos NA, etal., Curr Eye Res. 2013 Oct;38(10):1036-48. doi: 10.3109/02713683.2013.804094. Epub 2013 Jul 10.
208. Tuon FF, etal., J Dermatol Sci. 2010 Jul;59(1):55-7. doi: 10.1016/j.jdermsci.2010.04.009. Epub 2010 May 20.
209. Vainas T, etal., J Vasc Surg. 2006 Aug;44(2):326-32.
210. van Well GT, etal., PLoS One. 2012;7(5):e35837. doi: 10.1371/journal.pone.0035837. Epub 2012 May 25.
211. van Well GT, etal., PLoS One. 2013 May 14;8(5):e64252. doi: 10.1371/journal.pone.0064252. Print 2013.
212. Velez DR, etal., Hum Genet. 2009 Nov;126(5):643-53. Epub 2009 Jul 3.
213. Viriyakosol S, etal., Infect Immun. 2006 Feb;74(2):887-95.
214. Wang CS and Dong Z, Zhonghua Er Bi Yan Hou Ke Za Zhi. 2003 Aug;38(4):243-6.
215. Wang GB, etal., Zhonghua Er Ke Za Zhi. 2008 Jan;46(1):49-54.
216. Wang J, etal., Mol Vis. 2011 Jan 18;17:170-6.
217. Wang N, etal., Curr Eye Res. 2014 Jan;39(1):47-52. doi: 10.3109/02713683.2013.827212. Epub 2013 Sep 27.
218. Wang S, etal., Dis Model Mech. 2010 Jan-Feb;3(1-2):92-103. doi: 10.1242/dmm.003533. Epub 2009 Dec 28.
219. Wieland CW, etal., Eur Respir J. 2010 Jul 22.
220. Wolfs TG, etal., J Immunol. 2002 Feb 1;168(3):1286-93.
221. Wu FX, etal., Int J Med Sci. 2010 Aug 2;7(5):251-9.
222. Wu HS, etal., Hepatobiliary Pancreat Dis Int. 2005 Nov;4(4):609-13.
223. Wu YW, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2009 Feb;32(2):111-4.
224. Xu J, etal., J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):140-6.
225. Yan CG, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007 Dec;19(12):731-4.
226. Yan JE, etal., Neurosci Lett. 2012 Sep 20;526(1):54-8. doi: 10.1016/j.neulet.2012.08.012. Epub 2012 Aug 15.
227. Yang CX, etal., Tissue Antigens. 2013 Apr;81(4):221-6. doi: 10.1111/tan.12096.
228. Yang IA, etal., Atherosclerosis. 2003 Sep;170(1):187-90.
229. Yao XM, etal., Hepatol Res. 2009 Mar 10.
230. Yao YM, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2003 Nov;15(11):646-50.
231. Ye D, etal., Gut. 2012 Jul;61(7):1058-67. doi: 10.1136/gutjnl-2011-300269. Epub 2012 Jan 17.
232. Yin Y, etal., Cell Physiol Biochem. 2017;42(2):469-479. doi: 10.1159/000477594. Epub 2017 Jun 5.
233. Young KC, etal., Exp Lung Res. 2010 Mar;36(2):111-9.
234. Yuan FF, etal., Immunol Cell Biol. 2008 Mar-Apr;86(3):268-70. Epub 2008 Jan 8.
235. Zager RA, etal., Am J Physiol Renal Physiol. 2006 Sep;291(3):F546-56. Epub 2006 Apr 25.
236. Zanotti G, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L52-63. Epub 2009 Apr 17.
237. Zareparsi S, etal., Hum Mol Genet. 2005 Jun 1;14(11):1449-55. Epub 2005 Apr 13.
238. Zee RY, etal., Stroke. 2005 Jan;36(1):154-7. Epub 2004 Dec 2.
239. Zhang L, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2006 Mar;18(3):161-4.
240. Zhang Q, etal., Acta Otolaryngol. 2013 Feb;133(2):165-73. doi: 10.3109/00016489.2012.717713. Epub 2012 Nov 19.
241. Zhang X, etal., J Clin Invest. 2006 Nov;116(11):3050-9. Epub 2006 Oct 19.
242. Zhao H, etal., J Immunol. 2010 May 1;184(9):5308-14. Epub 2010 Mar 31.
243. Zheng XY, etal., Chin J Integr Med. 2012 Dec;18(12):918-24. doi: 10.1007/s11655-012-1295-1. Epub 2012 Dec 13.
244. Zheng Z, etal., Brain Res. 2012 Dec 13;1489:90-7. doi: 10.1016/j.brainres.2012.10.014. Epub 2012 Oct 24.
245. Zhou R, etal., Invest Ophthalmol Vis Sci. 2012 Oct 25;53(11):7382-8. doi: 10.1167/iovs.12-10238.
246. Zhu W, etal., Inflamm Res. 2011 Oct;60(10):937-45. doi: 10.1007/s00011-011-0354-1. Epub 2011 Jun 21.
Additional References at PubMed
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PMID:101590   PMID:123543   PMID:202651   PMID:202969   PMID:325138   PMID:326565   PMID:326955   PMID:333293   PMID:342603   PMID:342667   PMID:359704   PMID:368244  
PMID:478638   PMID:501093   PMID:627714   PMID:681749   PMID:792337   PMID:915285   PMID:1086804   PMID:1097575   PMID:1244416   PMID:1373998   PMID:1376353   PMID:1541912  
PMID:1555775   PMID:1579857   PMID:1752882   PMID:1815711   PMID:2272660   PMID:2277589   PMID:2509612   PMID:2572648   PMID:2631797   PMID:2788176   PMID:2848174   PMID:2998065  
PMID:3397181   PMID:3884708   PMID:3886795   PMID:4877918   PMID:6491291   PMID:6985638   PMID:7365261   PMID:7521367   PMID:7622247   PMID:7650365   PMID:7822029   PMID:7829969  
PMID:7849398   PMID:7927709   PMID:8037746   PMID:8330899   PMID:8335946   PMID:8428530   PMID:8606102   PMID:8654505   PMID:8765479   PMID:8838309   PMID:8890215   PMID:8921956  
PMID:8982246   PMID:9043949   PMID:9108410   PMID:9177560   PMID:9321479   PMID:9403730   PMID:9403834   PMID:9596750   PMID:9851930   PMID:9989976   PMID:10047546   PMID:10047547  
PMID:10087992   PMID:10201887   PMID:10229796   PMID:10349636   PMID:10358184   PMID:10431187   PMID:10452977   PMID:10500213   PMID:10548109   PMID:10549626   PMID:10607756   PMID:10623794  
PMID:10630301   PMID:10663571   PMID:10669111   PMID:10679411   PMID:10725698   PMID:10734131   PMID:10770809   PMID:10783135   PMID:10835634   PMID:10880523   PMID:10952994   PMID:11042159  
PMID:11061032   PMID:11062499   PMID:11067888   PMID:11069716   PMID:11076861   PMID:11081518   PMID:11104518   PMID:11123338   PMID:11123339   PMID:11145687   PMID:11145696   PMID:11159012  
PMID:11160328   PMID:11171016   PMID:11217851   PMID:11254600   PMID:11261784   PMID:11286707   PMID:11294571   PMID:11310845   PMID:11313410   PMID:11343210   PMID:11349049   PMID:11489994  
PMID:11490012   PMID:11500829   PMID:11544199   PMID:11686851   PMID:11739561   PMID:11748204   PMID:11777976   PMID:11778656   PMID:11801671   PMID:11854525   PMID:11884465   PMID:11912201  
PMID:11923412   PMID:11962736   PMID:11970998   PMID:11992285   PMID:11994480   PMID:12003842   PMID:12020131   PMID:12021251   PMID:12055204   PMID:12055206   PMID:12055258   PMID:12069074  
PMID:12072368   PMID:12117914   PMID:12133979   PMID:12165539   PMID:12183533   PMID:12195388   PMID:12196527   PMID:12218091   PMID:12234819   PMID:12244136   PMID:12244183   PMID:12244198  
PMID:12354379   PMID:12355432   PMID:12356687   PMID:12370224   PMID:12402188   PMID:12411706   PMID:12421970   PMID:12424240   PMID:12447441   PMID:12466142   PMID:12466851   PMID:12477932  
PMID:12486107   PMID:12496429   PMID:12515817   PMID:12532024   PMID:12569171   PMID:12592402   PMID:12616480   PMID:12616500   PMID:12625509   PMID:12640135   PMID:12655047   PMID:12663667  
PMID:12665857   PMID:12671050   PMID:12672079   PMID:12682225   PMID:12686553   PMID:12707317   PMID:12707353   PMID:12727921   PMID:12730691   PMID:12777373   PMID:12782711   PMID:12794144  
PMID:12794153   PMID:12824464   PMID:12825186   PMID:12854089   PMID:12855817   PMID:12864815   PMID:12865424   PMID:12875990   PMID:12888452   PMID:12890349   PMID:12890428   PMID:12904319  
PMID:12917260   PMID:12918124   PMID:12927920   PMID:12941697   PMID:12960264   PMID:12960338   PMID:12960345   PMID:14500530   PMID:14517278   PMID:14517279   PMID:14530354   PMID:14551216  
PMID:14556004   PMID:14561708   PMID:14568952   PMID:14573621   PMID:14579265   PMID:14617520   PMID:14623167   PMID:14633605   PMID:14634059   PMID:14634093   PMID:14634130   PMID:14634135  
PMID:14636418   PMID:14644093   PMID:14657211   PMID:14660645   PMID:14688095   PMID:14688304   PMID:14691481   PMID:14699006   PMID:14734763   PMID:14739339   PMID:14742522   PMID:14742577  
PMID:14744795   PMID:14749364   PMID:14752288   PMID:14764599   PMID:14764668   PMID:14764737   PMID:14966433   PMID:14970116   PMID:14976262   PMID:14976600   PMID:14978024   PMID:14978090  
PMID:14978111   PMID:15004173   PMID:15004187   PMID:15004557   PMID:15029200   PMID:15034058   PMID:15034062   PMID:15034070   PMID:15039311   PMID:15039466   PMID:15048726   PMID:15072965  
PMID:15086422   PMID:15100369   PMID:15128808   PMID:15128825   PMID:15132988   PMID:15137944   PMID:15138173   PMID:15143282   PMID:15163536   PMID:15178705   PMID:15208271   PMID:15213237  
PMID:15214027   PMID:15240691   PMID:15240706   PMID:15240744   PMID:15249654   PMID:15260992   PMID:15265925   PMID:15271679   PMID:15271901   PMID:15280422   PMID:15282190   PMID:15321997  
PMID:15322195   PMID:15322203   PMID:15331330   PMID:15337750   PMID:15353553   PMID:15356140   PMID:15358664   PMID:15368304   PMID:15369778   PMID:15375173   PMID:15381113   PMID:15458779  
PMID:15458952   PMID:15464243   PMID:15475494   PMID:15485838   PMID:15494520   PMID:15501775   PMID:15501798   PMID:15509550   PMID:15514106   PMID:15522205   PMID:15528333   PMID:15530921  
PMID:15537384   PMID:15538945   PMID:15539158   PMID:15557205   PMID:15557622   PMID:15563689   PMID:15585830   PMID:15585866   PMID:15611251   PMID:15614130   PMID:15618172   PMID:15618193  
PMID:15630134   PMID:15634894   PMID:15638128   PMID:15650774   PMID:15654341   PMID:15659328   PMID:15661922   PMID:15664935   PMID:15671286   PMID:15684036   PMID:15695506   PMID:15699133  
PMID:15701712   PMID:15716415   PMID:15718365   PMID:15718493   PMID:15731053   PMID:15731086   PMID:15737196   PMID:15738005   PMID:15755814   PMID:15773898   PMID:15778388   PMID:15778492  
PMID:15781585   PMID:15784548   PMID:15784698   PMID:15795240   PMID:15814731   PMID:15826931   PMID:15845500   PMID:15849871   PMID:15852007   PMID:15860593   PMID:15864310   PMID:15879150  
PMID:15896296   PMID:15902499   PMID:15905502   PMID:15905547   PMID:15905587   PMID:15919369   PMID:15919371   PMID:15920727   PMID:15944297   PMID:15961512   PMID:15964841   PMID:15967420  
PMID:15972657   PMID:15972679   PMID:15972684   PMID:15994412   PMID:15996225   PMID:16001129   PMID:16002681   PMID:16002687   PMID:16002720   PMID:16024722   PMID:16025156   PMID:16034104  
PMID:16040976   PMID:16041030   PMID:16045730   PMID:16052598   PMID:16081822   PMID:16093364   PMID:16113279   PMID:16113324   PMID:16113340   PMID:16116197   PMID:16116224   PMID:16118350  
PMID:16141072   PMID:16141073   PMID:16142239   PMID:16143103   PMID:16148103   PMID:16148139   PMID:16148141   PMID:16154177   PMID:16163057   PMID:16174756   PMID:16177320   PMID:16179373  
PMID:16186163   PMID:16210584   PMID:16236128   PMID:16237097   PMID:16237099   PMID:16239544   PMID:16239556   PMID:16239576   PMID:16244651   PMID:16254214   PMID:16260493   PMID:16272176  
PMID:16272281   PMID:16272291   PMID:16272328   PMID:16272344   PMID:16283355   PMID:16284190   PMID:16284241   PMID:16291660   PMID:16292312   PMID:16293680   PMID:16299309   PMID:16299326  
PMID:16301658   PMID:16301676   PMID:16309564   PMID:16316333   PMID:16322526   PMID:16323245   PMID:16325814   PMID:16333033   PMID:16338228   PMID:16339563   PMID:16344599   PMID:16369019  
PMID:16391018   PMID:16393954   PMID:16394008   PMID:16403908   PMID:16413386   PMID:16413499   PMID:16413927   PMID:16424940   PMID:16425356   PMID:16439473   PMID:16455798   PMID:16455994  
PMID:16456012   PMID:16456013   PMID:16460678   PMID:16461338   PMID:16461458   PMID:16467877   PMID:16469054   PMID:16473828   PMID:16481293   PMID:16481302   PMID:16489357   PMID:16493066  
PMID:16493068   PMID:16500244   PMID:16506285   PMID:16507888   PMID:16514062   PMID:16517740   PMID:16518342   PMID:16523497   PMID:16537813   PMID:16547261   PMID:16547265   PMID:16574244  
PMID:16585574   PMID:16602821   PMID:16603631   PMID:16606831   PMID:16609927   PMID:16611887   PMID:16622187   PMID:16622195   PMID:16622218   PMID:16628628   PMID:16648192   PMID:16651610  
PMID:16670292   PMID:16670307   PMID:16670325   PMID:16670331   PMID:16675600   PMID:16675630   PMID:16688168   PMID:16703567   PMID:16706798   PMID:16709832   PMID:16709864   PMID:16709871  
PMID:16714560   PMID:16717116   PMID:16733795   PMID:16738669   PMID:16751103   PMID:16754684   PMID:16757566   PMID:16766576   PMID:16781673   PMID:16782847   PMID:16785556   PMID:16790781  
PMID:16809643   PMID:16814255   PMID:16818783   PMID:16820585   PMID:16829963   PMID:16831874   PMID:16836770   PMID:16847070   PMID:16849485   PMID:16849487   PMID:16861639   PMID:16863919  
PMID:16877769   PMID:16879256   PMID:16886064   PMID:16888154   PMID:16891416   PMID:16895974   PMID:16912041   PMID:16916914   PMID:16920916   PMID:16920968   PMID:16926427   PMID:16936244  
PMID:16943680   PMID:16946018   PMID:16951362   PMID:16954198   PMID:16954393   PMID:16963319   PMID:16980981   PMID:16982918   PMID:16983331   PMID:16984919   PMID:17000122   PMID:17000866  
PMID:17004992   PMID:17010424   PMID:17026481   PMID:17034585   PMID:17034761   PMID:17034774   PMID:17035347   PMID:17038589   PMID:17049055   PMID:17056563   PMID:17060475   PMID:17062605  
PMID:17071719   PMID:17074859   PMID:17082484   PMID:17082602   PMID:17114424   PMID:17114485   PMID:17114491   PMID:17117477   PMID:17118979   PMID:17123997   PMID:17135446   PMID:17142724  
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