Tlr4 (toll-like receptor 4) - Rat Genome Database

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Gene: Tlr4 (toll-like receptor 4) Mus musculus
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Symbol: Tlr4
Name: toll-like receptor 4
RGD ID: 737014
MGI Page MGI
Description: Enables lipopolysaccharide immune receptor activity. Involved in several processes, including positive regulation of defense response; regulation of cytokine production; and response to lipopolysaccharide. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; regulation of cytokine production involved in immune response; and response to bacterium. Located in plasma membrane. Part of receptor complex. Is expressed in several structures, including early embryo; genitourinary system; inner cell mass; intestine; and skin. Used to study pulmonary emphysema. Human ortholog(s) of this gene implicated in several diseases, including allergic contact dermatitis (multiple); artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Orthologous to human TLR4 (toll like receptor 4).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: lipopolysaccharide response; Lps; Ly87; Ran/M1; Ras; Rasl2-8; Toll like receptor 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39466,745,788 - 66,765,338 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl466,745,821 - 66,848,521 (+)EnsemblGRCm39 Ensembl
GRCm38466,827,551 - 66,846,581 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl466,827,584 - 66,930,284 (+)EnsemblGRCm38mm10GRCm38
MGSCv37466,488,845 - 66,503,831 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36466,314,172 - 66,329,158 (+)NCBIMGSCv36mm8
Celera465,431,141 - 65,446,127 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model