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Gene: Pdk4 (pyruvate dehydrogenase kinase, isoenzyme 4) Mus musculus
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Symbol: Pdk4
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Description: Predicted to have ATP binding activity; protein serine/threonine kinase activity; and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including insulin receptor signaling pathway; regulation of bone resorption; and regulation of fatty acid metabolic process. Localizes to mitochondrial inner membrane. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and skin. Orthologous to human PDK4 (pyruvate dehydrogenase kinase 4); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AV005916; pyruvate dehydrogenase kinase 4; pyruvate dehydrogenase kinase, isozyme 4
Orthologs:
Homo sapiens (human) : PDK4 (pyruvate dehydrogenase kinase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdk4 (pyruvate dehydrogenase kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdk4 (pyruvate dehydrogenase kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDK4 (pyruvate dehydrogenase kinase 4)
Canis lupus familiaris (dog) : PDK4 (pyruvate dehydrogenase kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdk4 (pyruvate dehydrogenase kinase 4)
Sus scrofa (pig) : PDK4 (pyruvate dehydrogenase kinase 4)
Chlorocebus sabaeus (African green monkey) : PDK4 (pyruvate dehydrogenase kinase 4)
Heterocephalus glaber (naked mole-rat) : Pdk4 (pyruvate dehydrogenase kinase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl65,483,351 - 5,496,309 (-)EnsemblGRCm38mm10GRCm38
GRCm3865,483,351 - 5,496,278 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3765,433,351 - 5,446,278 (-)NCBIGRCm37mm9NCBIm37
MGSCv3665,433,351 - 5,446,278 (-)NCBImm8
Celera65,632,922 - 5,645,841 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map62.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdk4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69114
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.